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Book review: Where'd You Go, Bernadette by Maria Semple
April 24, 2016 September 3, 2018 Leave a comment
Where'd You Go, Bernadette by Maria Semple
Rating: ★★☆☆☆
Links: Amazon • Goodreads
Source: Borrowed
A compulsively readable and touching novel about misplaced genius and a mother and daughter's role in an absurd world.
Bernadette Fox is notorious. To her Microsoft-guru husband, she's a fearlessly opinionated partner; to fellow private-school mothers in Seattle, she's a disgrace; to design mavens, she's a revolutionary architect, and to 15-year-old Bee, she is a best friend and, simply, Mom.
Then Bernadette disappears. It began when Bee aced her report card and claimed her promised reward: a family trip to Antarctica. But Bernadette's intensifying allergy to Seattle – and people in general – has made her so agoraphobic that a virtual assistant in India now runs her most basic errands. A trip to the end of the earth is problematic.
To find her mother, Bee compiles email messages, official documents, secret correspondence – creating a compulsively readable and touching novel about misplaced genius and a mother and daughter's role in an absurd world.
I read this book because supposedly it is considered satire, and my reading challenge stipulates that I must read a satirical book this year. Having finished this book, I am not 100% convinced that it's satire. I think it may just be a book about awful adults and their daughter who has miraculously turned out to be a productive member of society.
Bernadette Fox was once a revolutionary architect, so talented that she won a MacArthur grant for her work. Then, after disaster struck one of her projects, she never so much as drew another floor plan. These days, Bernadette is an antisocial recluse who outsources even her grocery shopping to Manjula, her Indian virtual assistant. Bernadette's husband, Elgie, is a famous employee of Microsoft. His TED Talk is the #4 viewed of all time, and his work could change the world.
These two intelligent, Ivy League-educated parents manage to screw up their daughter's life in just about every way possible, and yet somehow, Bee is a clever, well-adjusted young woman. All the ways in which these parents screw up Bee's life is basically the premise of this book.
I couldn't figure out how I was supposed to react to this. It was written in such a way that I think I was supposed to find it funny, or maybe I was just supposed to see Bernadette and Elgie as these unpredictable, eccentric people? But I didn't. I thought they were irresponsible, their relationship was unhealthy, and the way that they acted with blatant disregard for their daughter was just too much.
The premise of this book, of course, is that Bernadette disappears. (That much is clear from the title.) Her frustration is understandable: her little quirks have been blown out of proportion by a neighbor that she doesn't get along with. Rather than stay to defend herself, though, she falls off the face of the earth.
My first problem with this is that it doesn't fit at all with the Bernadette we'd met earlier in the book. Bernadette is quirky, yes. She doesn't like to leave the house except to take her daughter to and from school. She hires Manjula to make phone calls for her. Her home is in such a state of disrepair that a gardener comes to weed-whack… indoors. She has blackberry bushes growing out of control in her basement. Yet, though all of that, it's clear that she loves her daughter. Bernadette and Bee are best friends. They stand up for each other. They have a special bond. So the fact that Bernadette would just disappear without giving Bee a heads up doesn't fit with her character at all.
My second problem with this is that Elgie doesn't really care. Again, this doesn't seem to fit with his character. Sure, he's focused on his work. His job takes up a good portion of his life, especially since he's the head of a huge project and has a large team to supervise. But we never get the impression that he doesn't care about Bernadette. Actually, at the beginning of the book, it would seem that, despite Elgie's annoyance at some of Bernadette's antics (he's not a huge fan of Manjula), the two are still very much in love. That's why a lot of what happens toward the end of this book is utter nonsense.
I think I'm actually in the minority, having actually enjoyed the writing style. It's almost like a scrapbook, almost, with emails, faxes, letters, and articles interspersed with Bee's observations. It reminded me of some books that I really liked when I was younger.
Overall, I guess this really depends on the reader. (But don't all books?) For me, it was just too much and too unbelievable. For someone else, it might be engaging and dramatic and hilarious.
For my 2016 reading challenge, I'm crossing off #38: a satirical book.


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2-for-1 Passes
All Cappers
VMI vs. East Tennessee State - 2/15/20 College Basketball Pick, Odds, and Prediction
Photo by Michael Thomas Shroyer-USA TODAY Sports
Shane Mickle February 14, 2020 8:29 pm
East Tennessee State (22-4) at VMI Keydets (7-19)
College Basketball: Saturday, February 15, 2020 at 1:00 pm (Cameron Hall)
The Line: VMI +12 -- Over/Under: 139 Click Here for the Latest Odds
Where to Watch: ESPN3 Stream College Basketball all season on ESPN+. Sign up now!
The East Tennessee State Buccaneers (22-4, CONF 11-2) and VMI Keydets (7-19, CONF 2-11) face off in a Southern Conference showdown at Cameron Hall. These teams faced off in early January, and the Keydets shocked everyone by keeping it close against ETSU.
The Buccaneers come into this game hot having won nine of the last ten games, but even they aren't immune to a bad loss. Late in January against Mercer as 14 point favorites the Buccaneers lost 71-55.
None of the stats for the Buccaneers are really eye-popping, but they are just solid. ETSU is averaging 74.2 points while giving up 64.7 points per game.
Get Our Experts BEST BETS For All Of The Games CLICK HERE
The Buccaneers don't really have a star, but they have a lot of good solid players. East Tennessee State has four players averaging at least ten points, and eight players averaging at least five.
As good as the Buccaneers have been, the Keydets have been about that bad. VMI comes into this game having lost eight of the last ten games and only covered five.
The Keydets offense has been fine, but their defense has been an issue giving up 74.7 points per game overall.
VMI is led by Travis Evee who is averaging 12 points per game, but he hasn't been as productive as of late, not reaching his average in any of the last five games.
In VMI"s last game against Chattanooga, they gave up 86 points, with 47 of those coming in the second half.
The Keydets are 3-7 ATS in their last ten home games. The over is 6-2 in Buccaneers' last eight games overall. The over is 8-1 in VMI's last nine home games. The under is 7-3 in the last ten meetings played between the Buccaneers and Keydets.
The Buccaneers had that one slip up in the last ten games, but there won't be any slip-ups in this game. The Keydets struggles to play defense is going to lead to a lot of scoring by the Buccaneers, and a cover by the visiting team.
See Who Our Experts Picked To Win
Shane's Pick East Tennessee State -12
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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.
UMass vs. Dayton - 2/15/20 College Basketball Pick, Odds, and Prediction
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AUTHOR: Shane Mickle
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redpajama_set_name: RedPajamaCommonCrawl


Jane Carton, Tash Duff and Lee Tabas pose in front of one of their beautiful creations at the Haverford Train Station.
Haverford Civic Association Board member, Lee Tabas, and veteran supporters and past Board Members Jane Carton and Tash Duff did it again!
The planters never looked better.
Haverford Civic Association Board member, Lee Tabas, recently spruced (no pun intended) up the two planters we maintain at the Haverford Train Station. Taking over for Jane Carton, who had done this for years, Lee planted some new cacti and trimmed the small evergreen tree found in one of the planters.


Would you buy a D700 today and at what price?
Re: Would you buy a D700 today and at what price?
I would not spend more than retail on the D700 of $2199. If you are going to spend up to $2800 max why wouldnt you buy a d800 for $200 more?
I'd pay $1300 for it, tops.
10 Is D850 compatible with AF at f8 for teleconverter?


Feliny has been working with the aquaculture team since November 2014. She is a sea cucumber technician working in the Velondriake LMMA. She comes from Andavadoaka and as a vezo has always been passionate by everything related to the sea. She is building her experience with communities in order to provide them with a more sustainable livelihood.


Pantoprazole and Domperidone Sustained Release Capsules are a combination formulation for patients having acidity along with gastric acid reflux. PD-SR offers sustained symptomatic relief over 24hours for patients troubled with hyperacidity and dysmotility disorders. Pantoprazole provides rapid relief from acidity whereas Domperidone works towards preventing nausea, vomiting and acid reflux associated with heartburn.
Pantoprazole is a proton pump inhibitor, which accumulates in the acidic compartment of parietal cells and is converted to the active form. The active form inhibits the final step in the secretion of hydrochloric acid in the stomach by specific blockade of the H+/K+ATPase enzyme, the proton pumps of the parietal cells. The inhibition of proton pumps is dose-dependent and affects both basal and stimulated acid secretion.
It is rapidly absorbed after oral administration and maximal plasma concentration is achieved even after one single 40 mg oral dose with onset of action 2-4 hours. Oral bioavailability is 77%. Food has no influence on the bioavailability. For pantoprazole renal elimination is the major route of excretion (about 80%). Rest undergoes low first pass hepatic excretion.
Domperidone exerts gastroprokinetic effect due to its antagonist action on dopamine receptors D2 (D2R). Inhibition of these receptors increases motility of GI tract that fastens gastric emptying and prevents nausea and vomiting. Antagonist effect at D2 receptors increases the pressure at lower esophageal sphincter so that reflux of stomach contents into esophagus is prevented. It also has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which regulates nausea and vomiting.
Peak plasma levels of domperidone occur within 30 minutes after oral administration on empty stomach. When taken after a meal, domperidone's bioavailability is enhanced. However, patients with gastrointestinal complaints should take domperidone 15-30 minutes before a meal. Plasma half-life after a single oral dose is 7-9 hours in healthy subjects. Urinary and faecal excretions of domperidone amount to 31% and 66% of the oral dose, respectively.
Recommended to be prescribed when on NSAID therapies and other drug therapies where side effects are gastritis and heartburn.
The recommended dose of PD-SR capsules is one capsule daily before breakfast.
In patients with a known hypersensitivity to pantoprazole or domperidone or any other inactive ingredients of the capsules.
In conditions where stimulation of the gastric motility could be harmful: gastrointestinal haemorrhage, mechanical obstruction or perforation.
Diarrhoea, skin rash, dizziness, pruritus, galactorrhea, gynecomastia.
Advice the patients to stop taking the medication and report to their physician if they observe any uncommon side effects.
Symptomatic relief from gastritis due to pantoprazole therapy does not preclude the presence of gastric malignancy.
Achlorhydria/hypochlorhydria due to long term treatment with acid suppressing medications may lead to mal absorption of VitaminB12.
Patients on high dose/multiple dose/Long term PPI (proton pump inhibitor) therapy have been reported to have an increased risk for osteoporosis-related fractures of the hip, wrist or spine. Therefore patients who have or are at risk of osteoporosis should be given PPI treatments following proper guidelines.
There have been rare reports of hypomagnesaemia in patients treated with PPIs for at least 3 months. It is manifested with tetany, arrhythmias and seizures mostly after a year of therapy.
Magnesium levels are to be monitored in patients who are on concomitant treatment with digoxin or drugs that may cause hypomagnesaemia (e.g., diuretics).
In long-term treatment, especially when exceeding a treatment period of 1 year, patients should be regularly monitored.
Treatment with proton pump inhibitors may lead to a slightly increased risk of gastrointestinal infections caused by bacteria such as Salmonella and Campylobacter.
Notify the patients to consult their physicians if the post-prandial symptoms persist for more than 2 weeks even after being on therapy. Also when nausea and vomiting persists for more than 48hours.
Domperidone is not recommended for the treatment of motion sickness.
Cardiac risk may be higher in patients older than 60 years and at daily doses of more than 30 mg.
In patients who have existing prolongation of cardiac conduction intervals, particularly the QTc, and in patients with significant electrolyte disturbances or underlying cardiac diseases such as congestive heart failure, caution should be exercised while using domperidone and/or co-administration with oral ketoconazole, erythromycin or other potent CYP3A4 inhibitors that prolong the QTc intervals.
Patients on concomitant treatment with PPIs and warfarin should be monitored for increase in INR and prothrombin time.
Anti cholinergics, antimuscarinic agents antagonize the activity of domperidone.
PD-SR should be used in pregnancy if its use is justified by the anticipated therapeutic benefit.
Pantoprazole and Domperidone are excreted into the breast milk. PD-SR should not be prescribed for lactating mothers. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the benefit of the drug to the mother.
Information provided above is for reference purpose only and has been compiled for use by healthcare practitioners. Please consult your physician to understand how the product affects you, its dosages, side-effects and further information.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indications prescribed by your physician.
Every effort has been made to ensure that the information provided by Pharma Synth Formulations Ltd. ('PSFL') is accurate, up-to-date, and complete, but no guarantee is made to that effect. PSFL does not endorse drugs, diagnose patients or recommend therapy and is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. PSFL does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.


Mary was born on March 19, 1931 and passed away on Thursday, February 7, 2019.
Funeral Services will be Monday, February 11, 2019 at R.E. Shearwood Memorial Chapel with Reverend Dorothy French officiating. Burial will follow to West Liberty Cemetery under the direction of King & Shearwood Funeral Home of Stigler.


text:
@interface ReachabilityManager : NSObject <ReachabilityManagerProtocol>

@end

redpajama_set_name: RedPajamaGithub


Kia Motors (UK) Limited has announced a range of offers for the second quarter of 2019 available at the 191-strong dealership network.
The best-selling New Kia Sportage and Venga are now available on the Kia Scrappage scheme with a £2,500 saving when you scrap an old car of seven years or more. The Stonic and Picanto are also available on the scheme with savings of £2,500 and £2,000 respectively. Like all Kia models, those included in the scrappage scheme offer the brand's industry-leading seven-year/100,000 mile warranty.
A number of models benefit from an attractive 2.9 per cent Personal Contract Purchase rate: the All-New Ceed (hatchback and Sportswagon), All-New ProCeed, New Sportage and – new to this quarter's offers – Sorento.
Kia's seven-seater SUV, the Kia Sorento, comes 2.9 per cent PCP with up to £3,000 deposit contribution. With this offer, the Sorento 'GT-Line' 2.2 CRDi auto is available at £319 per month*. 'GT-Line' comes with sports-inspired detailing, leather upholstery, sat nav, smart key, engine start button and heated steering wheel as standard.
The award-winning Kia Stinger is available from £29,995 or £329 per month** in its 'GT-Line' 2.0 T-GDi 242bhp automatic variant. Other derivatives in the Stinger range come with a PCP deposit allowance of £2,500 and 5.9 per cent APR, including the range-topping 'GT S' 3.3 T-GDi 361bhp derivative.
All offers are available from 1st April 2019 to 30th June 2019.
Kia Scrappage Scheme: Requires the old vehicle to have been registered before 30th June 2012 and owned by the customer for more than three months. The Kia dealer will complete all the paperwork and arrange for the old vehicle to be destroyed through regulated and established channels. There is no additional trade-in value of the car to be scrapped. The Kia Scrappage Scheme and the 2.9 per cent APR cannot be used in conjunction with any other offer or promotion.
*Price for a Sorento 'GT-Line' 2.2 CRDi auto with standard paint and based on a customer deposit of £9,077.99 with a finance deposit contribution of £3,000 on a 36-month/10,000 mile-per annum Personal Contract Purchase agreement at 2.9 per cent APR. Kia Finance, RH2 9AQ. T&Cs apply. Subject to status. 18s or over. Guarantee may be required.
** Price of a Stinger 'GT-Line' 2.0 T-GDi auto with standard paint and based on a customer deposit of £7,694.73 with a customer saving of £2,480 customer saving on 36-month/10,000 mile-per-annum Personal Contract Purchase agreement at 5.9 per cent APR. Kia Finance, RH2 9AQ. T&Cs apply. Subject to status. 18s or over. Guarantee may be required.


Piel C.P. 500 tandem twin-engine light aircraft.
There are occasions when a target, though moving, does not produce a Doppler shift. An aircraft moving tangentially to the radar beam has no radial component to the radar, hence no Doppler shift. This condition is referred to as tangential fade. This condition exists only for a short period because, as the target continues moving, it will have a Doppler component away from radar and will reappear.
A condition in which a target does not appear on the radar screen when it is moving tangentially to the radar while using a moving target indicator (MTI). This phenomenon is temporary and can be overcome by canceling the MTI.


Chelsea manager Antonio Conte has expressed his belief that Arsenal are a "potential rival" for his side this season because of the experience of coach Arsene Wenger.
The two sides meet in the Community shield at Wembley on Sunday, ahead of the start of the Premier League campaign next weekend.
And Conte has stressed that overcoming a side of Arsenal's quality will be a difficult challenge throughout the season.
"Arsenal is a potential rival this season because I consider Arsenal one of six teams ready to fight to win the title and I consider Arsene Wenger to be one of the best coaches," the Italian coach told Chelsea's official website.
"He is a very good coach and he has had a lot of time to build his team and his squad, and I think he is the right choice for them. I'm not surprised he stayed because he is one of the best in the world and Arsenal is one of the best teams."
Turning his attention to the season ahead, Conte has admitted that repeating last season's success will not be easy.
"To be coach for a great team in England is great, but also gives you a lot of responsibility," he added. "You know that when you arrive in England, you must be ready to fight with big teams, with big players against big coaches. This league has made me better than before, I am sure about this.
"In England, you win the title and the next season the teams prepare to fight you with all their strength. They go to the transfer market, they try to improve and it is very difficult to repeat the success of the season before."


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text:
American flag & Americana
Anti-Federalist Papers
Election stories
Manifest Destiny & Pioneers
Religion & Government
Remember the Ladies
Signers of Declaration
Spies & Traitors
U.S. First Ladies
U.S. History (1783--99)
U.S. History (1800s)
U.S. History (aviation)
U.S. History (general military)
U.S. History (holidays)
U.S. history (naval)
U.S. History (sports)
This Day in History: Nathan Hale, spy for George Washington
On this day in 1776, an American Patriot is executed by the British. Nathan Hale's reported final words were brave and memorable. Maybe you've heard them? Hale declared: "I only regret that I have but one life to lose for my country."
Awesome! Brave.
Hale was attempting to help George Washington's army, then fighting a series of battles in and around New York. Americans had lost the Battle of Long Island in August 1776, but then they'd made a miraculous middle-of-the-night escape across the East River. A few weeks later, they were driven from New York. Fortunately, they won a much-needed victory at Harlem Heights not too long after that.
Washington was desperate for information about the British. He asked Lt. Colonel Thomas Knowlton to help him recruit volunteers. He needed spies! Knowlton turned to his Rangers for help. Only one person stepped forward: a young Captain under Knowlton's command, Nathan Hale.
Hale was a graduate from Yale who had been teaching when the American Revolution first began. He soon joined the army and obtained the rank of captain; he was a member of Knowlton's Rangers, a special corps that acted as a special scouting arm of the army. The Rangers were to take on tasks that involved a "special, delicate, and hazardous duty."
Interesting that, even among all those tough guys, Hale was the only one who wanted to volunteer to be a spy. Unfortunately, Hale's experience in spying did not match his enthusiasm.
Hale was supposed to enter enemy territory, posing as a school teacher. He was to gather any information that he could on the size, strength and location of the British and their fortifications. Unfortunately, Hale did not know how to write in code. Nor did he have invisible ink. If he was caught with his notes, it would be very obvious what he was doing.
Details about Hale's time behind enemy lines are sketchy. It appears that he did gather some information about the British troops and their arms, but stories vary about how he was actually captured. Perhaps he was betrayed by a Tory cousin. Or maybe he was simply tricked into revealing himself. Either way, he was brought before Lord William Howe on September 21. He did not deny what he was doing, and he was sentenced without a trial.
Reportedly, Hale was denied both a Bible and a minister before he was executed on September 22. He was nevertheless described as "calm." He "bore himself with gentle dignity, in the consciousness of rectitude and high intentions…" Another British soldier gave a similar description of Hale's final moments. Frederick Mackenzie said that Hale "behaved with great composure and resolution, saying he thought it the duty of every good officer to obey any orders given him by his Commander in Chief; and desired the spectators to be at all times prepared to meet death in whatever shape it might appear."
A British soldier was sent to report Hale's death to Washington. American Captain William Hull was present at that meeting and remembered the report of Hale's dying words: "I only regret that I have but one life to lose for my country."
To be fair, it should be noted that Hull was a good friend of Hale's. Some historians wonder if he could have created the famous last words on behalf of his friend, allowing "his friend the posthumous privilege of uttering" such a brave phrase.
Either way, Hale was yet another Patriot who gave his all so that we might have freedom.
Primary Sources & Further Reading:
Central Intelligence Agency, A Look Back . . . The Story of Nathan Hale
Glenn Peter Hastedt, Spies, Wiretaps, and Secret Operations: An Encyclopedia of American Espionage (2010)
M. William Phelps, Nathan Hale: The Life and Death of America's First Spy (2008)
Robert L. Tonsetic, Special Operations in the American Revolution (2013)
Samuel Clarke Clarke, Memoir of Gen. William Hull (1893)
Steve Sheinkin, King George: What Was His Problem?: Everything Your Schoolbooks Didn't Tell You About the American Revolution (2015)
please contact Colonial Press
info at colonialpressonline dot com
from Tara Ross
Thanks for loving history with me!
© Copyright 2020 by Tara Ross.


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ORACS
    0.8

Meta-heuristic for solving VRP problems.

Public Member Functions |
Private Member Functions |
Private Attributes |
List of all members

Init Class Reference

#include <init.h>

Public Member Functions

 	Init (std::string &file)

void 	showVehicleMatrix ()

 	Show the vehicle matrix.

void 	showDepotMatrix ()

 	Show the depot matrix.

void 	showCustomerMatrix ()

 	Show the customer matrix.

void 	showDistanceMatrix ()

 	Show the distance matrix.

void 	show ()

int 	getNoOfDepots () const

int 	getNoOfVehicleTypes () const

int 	getNoOfCustomers () const

const std::vector< std::vector< double > > & 	getVehicleMatrix () const

const std::vector< std::vector< double > > & 	getDepotMatrix () const

const std::vector< std::vector< double > > & 	getCustomerMatrix () const

const std::vector< std::vector< double > > & 	getDistanceMatrix () const

Private Member Functions

void 	showMatrix (std::vector< std::vector< double >> matrix)

void 	createDistanceMatrix ()

 	Create distance matrix based on the coordinates of all locations.

double 	distance (double x1, double y1, double x2, double y2)

 	Return distance of two (x,y) coordinates.  More...

Private Attributes

int 	d_noOfDepots

int 	d_noOfVehicleTypes

int 	d_noOfCustomers

std::vector< std::vector< double > > 	d_vehicleMatrix

std::vector< std::vector< double > > 	d_depotMatrix

std::vector< std::vector< double > > 	d_customerMatrix

std::vector< std::vector< double > > 	d_distanceMatrix

Detailed Description

Init class reads the data from the input file, and puts it in the approriate data members.

Definition at line 14 of file init.h.

Member Function Documentation

◆ distance()

          double Init::distance
          (
          double
          x1,

          double
          y1,

          double
          x2,

          double
          y2

          )

private

Return distance of two (x,y) coordinates.

Parameters

[in]	x1	x coordinate of the first point

[in]	y1	y coordinate of the first point

[in]	x2	x coordinate of the second point

[in]	y2	y coordinate of the second point

Returns

The distance between the two points

Definition at line 18 of file distance.cpp.

◆ getCustomerMatrix()

          const std::vector< std::vector< double > > & Init::getCustomerMatrix
          (
          	)
           const

inline

Find the matrix of all customers. Each row corresponds to one customer.

Returns

Matrix of all customers. Each row corresponds to one customer.

Definition at line 108 of file init.h.

◆ getDepotMatrix()

          const std::vector< std::vector< double > > & Init::getDepotMatrix
          (
          	)
           const

inline

Find the matrix of all depots. Each row corresponds to one depot.

Returns

Matrix of all depots. Each row corresponds to one depot.

Definition at line 99 of file init.h.

◆ getDistanceMatrix()

          const std::vector< std::vector< double > > & Init::getDistanceMatrix
          (
          	)
           const

inline

Find the matrix with all distances between each instance in the problem.

Returns

Matrix with all distances between every instance (Depots and Customers)

Definition at line 117 of file init.h.

◆ getNoOfCustomers()

          int Init::getNoOfCustomers
          (
          	)
           const

inline

Find the number of customers in the problem

Returns

Number of customers

Definition at line 81 of file init.h.

◆ getNoOfDepots()

          int Init::getNoOfDepots
          (
          	)
           const

inline

Find the number of depots in the problem.

Returns

Number of depots

Definition at line 63 of file init.h.

◆ getNoOfVehicleTypes()

          int Init::getNoOfVehicleTypes
          (
          	)
           const

inline

Find the number of vehicle types in the problem

Returns

Number of vehicle types

Definition at line 72 of file init.h.

◆ getVehicleMatrix()

          const std::vector< std::vector< double > > & Init::getVehicleMatrix
          (
          	)
           const

inline

Find the matrix of all vehicles. Each row corresponds to one vehicle.

Returns

Matrix of all vehicles. Each row corresponds to one vehicle.

Definition at line 90 of file init.h.

◆ show()

          void Init::show
          (
          	)

inline

Shows the vehicles, depots, customers, and the distance matrix.

Definition at line 51 of file init.h.

Member Data Documentation

◆ d_customerMatrix

          std::vector<std::vector<double> > Init::d_customerMatrix

private

List of all customers, and its attributes

Definition at line 21 of file init.h.

◆ d_depotMatrix

          std::vector<std::vector<double> > Init::d_depotMatrix

private

List of all depots, and its attributes

Definition at line 20 of file init.h.

◆ d_distanceMatrix

          std::vector<std::vector<double> > Init::d_distanceMatrix

private

Distance matrix for all instances of the problem

Definition at line 22 of file init.h.

◆ d_noOfCustomers

          int Init::d_noOfCustomers

private

Number of customers

Definition at line 18 of file init.h.

◆ d_noOfDepots

          int Init::d_noOfDepots

private

Number of depots

Definition at line 16 of file init.h.

◆ d_noOfVehicleTypes

          int Init::d_noOfVehicleTypes

private

Number of vehicle types

Definition at line 17 of file init.h.

◆ d_vehicleMatrix

          std::vector<std::vector<double> > Init::d_vehicleMatrix

private

List of all vehicles, and its attributes

Definition at line 19 of file init.h.

The documentation for this class was generated from the following files:

inc/init.h

src/init/createdistancematrix.cpp

src/init/distance.cpp

src/init/init.cpp

src/init/showcustomermatrix.cpp

src/init/showdepotmatrix.cpp

src/init/showdistancematrix.cpp

src/init/showmatrix.cpp

src/init/showvehiclematrix.cpp

<address class="footer">
Generated by

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text:
Karaism
Lasker introduces Karaism
An Introduction to the Oldest Surviving Alternative Judaism
Lasker, Daniel J.
Judaism: branches and groups
Judaism: life and practice
Jewish pluralism
alternative Judaism
Jewish sectarianism
I thought you would find this interesting: Karaism An Introduction to the Oldest Surviving Alternative Judaism Lasker, Daniel J. The Littman Library of Jewish Civilization (2022)
9781802070705 (eBook)
Karaite Judaism emerged in the ninth century in the Islamic Middle East as an alternative to the rabbinic Judaism of the Jewish majority. Karaites reject the underlying assumption of rabbinic Judaism, namely, that Jewish practice is to be based on two divinely revealed Torahs, a written one, embodied in the Five Books of Moses, and an oral one, eventually written down in rabbinic literature. Karaites accept as authoritative only the Written Torah, as they understand it, and their form of Judaism therefore differs greatly from that of most Jews. Despite its permanent minority status, Karaism has been an integral part of the Jewish people continuously for twelve centuries. It has contributed greatly to Jewish cultural achievements, while providing a powerful intellectual challenge to the majority form of Judaism. This book is the first to present a comprehensive overview of the entire story of Karaite Judaism: its unclear origins; a Golden Age of Karaism in the Land of Israel; migrations through the centuries; Karaites in the Holocaust; unique Jewish religious practices, beliefs, and philosophy; biblical exegesis and literary accomplishments; polemics and historiography; and the present-day revival of the Karaite community in the State of Israel.
'Daniel Lasker is an exemplary scholar with thorough command of the literature and an ability to convey the most foundational and fascinating elements of Karaism to a general readership.' Jessica Andruss, University of Virginia
'A true eminence in the field, Professor Lasker commands wide respect and recognition. His very fine, reliable introduction to Karaite Judaism will also engage an audience interested in larger questions, such as pluralism and self-definition.' Daniel Frank, Ohio State University
https://global.oup.com/academic/product/9781800855960?cc=us
Daniel J. Lasker is Norbert Blechner Professor of Jewish Values (Emeritus) at Ben-Gurion University of the Negev. In addition he has taught at many institutions of higher learning, including Yale, Princeton, the University of Toronto, Ohio State University, the University of Texas, and the University of Washington. His publications include Jewish Philosophical Polemics against Christianity in the Middle Ages (2nd edn., Littman Library, 2007) and From Judah Hadassi to Elijah Bashyatchi: Studies in Late Medieval Karaite Philosophy (2008).
1. Karaite Origins2. The Golden Age in the Land of Israel3. In Byzantium and Beyond4. Eastern European Karaites5. The Return to Israel6. Karaite Law and Religious Practices7. Principles of Karaism8.Theology9. Exegesis10. Polemics and Historiography11. Language and Literature12. The Future of KaraismBibliographyIndex


Julie Park, viola has graduated with a Bachelor of Music in Viola Performance with First Class Honours at the University of Auckland under the tutelage of Stephen Larsen. She has recently been offered the prestigious ABRSM Scholarship which covers full tuition and living cost to study her Master's degree at the Royal Academy of Music in London, 2018.
As a soloist, Julie has gained 'First in course Award' for solo performance in her first and second years studying at the University of Auckland. She was accepted into the 2014 Carl Flesch Akademie International Master Class in Germany to receive lessons from Professor Hartmut Rohde and was nominated to perform the J.C Bach Viola Concerto with the Baden Baden Philharmonia Orchestra. Additionally, she received the 'Ruth-Flesch-Gedachtnispreis' award/ scholarship selected by the conductor and judges. Being the grand winner of the 2016 Viva La Viola competition and the Auckland Philharmonia Orchestra's Young Soloist of the year, she performed the Forsyth Viola Concerto with the Auckland Philharmonia Orchestra in the Auckland Town Hall. She was selected as one of the three finalists to compete in the 2017 University of Auckland Graduation Gala Competition; being the first ever violist to be placed in the competition. She performed with the University of Auckland Symphony Orchestra and was awarded 2nd place in conjunction with the Graduation Gala Development Prize worth $2000. Julie was a semi-finalist and recipient of the inaugural Ian Dunsmore Memorial Juror's prize at the 2016 Gisborne International Music Competition and a semi-finalist of the Cecil Aronowitz International Viola Competition. She is also a recipient of numerous scholarships such as the Winifred Stiles Viola Prize, Spring Prize for String Player, Sagar-Vandewart Scholarship for String Players, Auckland Centennial Music Festival Scholarship, Winifred Stiles Viola Scholarship, Constance Herbert Memorial Scholarship, the 2017 Kate Edger Educational Charitable Trust Vinka Marinovich Awards in Music and the Rachel Bennett Arts Foundation Award.
As a chamber musician, Julie received 'First in course Award' in Chamber Music Performance three years in a row (2015, 2016 and 2017) whilst her study at the University of Auckland. Julie was nominated to attend the 2nd Summit of the Pacific Alliance of Music School (PAMS) in Beijing with her chamber group 'Mazzoli Trio' formed by the Head of Music Allan Badley and Artistic Director of the Pettman National Junior Academy of Music Edith Salzmann to showcase and represent The University of Auckland in 2015. Mazzoli Trio were the grand winners of the 2016 Auckland Chamber Music Society Prize Competition and 2nd place winners of the SALUT International Performing Arts Competition. They are also recipients of the 2016 Carl and Alberta Rosenfeldt Prize in Chamber Music and have been selected for the Chamber Music New Zealand Encompass tour to give concerts all around New Zealand in 2018. Julie has been invited to perform at various prestigious events such as the coronation of King Tupou VI of Tonga in 2015 as a New Zealand representative as well as recorded for the Atoll Label with her ensemble; Strata Quartet. She has collaborated and performed with numerous internationally renowned artists such as Clio Gould, Jonathan Morton, Stephen De Pledge, Amalia Hall, Ramon Jaffé and Alvin Wong. Julie was part of the winning chamber group in the Auckland Chamber Music Society Prize Competition two years in a row (2015, 2016) and a finalist of the Royal Over-Seas League Competition in 2015. She has also toured nationally as part of the Chamber Music New Zealand Tour with her Quintet; Pettman Players in 2016 and in 2017, she went on an ensemble tour to the UK collaborating with Clio Gould, Stephen De Pledge, Edith Salzmann and Benedict Lim as a part of the Pettman Ensemble.
As an orchestral musician, she has been Principal Viola of the Westlake Orchestras, Auckland Youth Orchestra, University of Auckland Symphony Orchestra, University of Auckland Chamber Orchestra and the NZSO National Youth Orchestra as a recipient of the 2016 Norbert Heuser Viola Award. Julie was selected to take part in the 2016 New Zealand Symphony Orchestra Fellowship Programme and was the winner of the inaugural 2016 Michael Monaghan Award from the NZSO Alex Lindsay Award Trust. She was chosen both as an Auckland Philharmonia Orchestra Orchestral Internship and the APO Young Soloist in the same year and currently working as a casual member of the New Zealand Symphony Orchestra and the Auckland Philharmonia Orchestra.


Home Theater Review reflects back on all of the products they've reviewed in 2015 and selects the ones that they feel are the best of the best--those that deserve a nod for pure performance, excellent value, or both. "The original SuperCinema 3D Array passive L/C/R soundbar earned a spot on our Best of 2013 list. GoldenEar has now introduced two new models with upgraded crossover technology, including the larger 3D Array XL that Brian Kahn recently reviewed. He called it 'the best-sounding soundbar I have heard' ." GoldenEar's SuperCinema 3D Array XL Soundbar is a Home Theater Best of 2015.


text:
Proadrenomedullin and copeptin in pediatric pneumonia: a prospective diagnostic accuracy study
Gabriel Alcoba1,2,
Sergio Manzano1,
Laurence Lacroix1,
Annick Galetto-Lacour1 &
Alain Gervaix1
Community-acquired-pneumonia is the leading cause of child mortality worldwide. Very few studies have explored the predictive value of Proadrenomedullin and Copeptin in pediatric severe pneumonia and bacteremia.
Proadrenomedullin and Copeptin were assessed as predictors for complicated community-acquired pneumonia (bacteremia, empyema) in 88 children aged 0 to 16 years presenting to the pediatric emergency department, using B.R.A.H.M.S. Kryptor Compact pro-ADM and Copeptin with the TRACE technology (time-resolved amplified cryptase emission). STARD standard reporting was used.
A complicated community-acquired pneumonia was found in 11 out of 88 children (12.5 %). Proadrenomedullin median values increased more than twofold, in complicated vs. uncomplicated (0.18 vs. 0.08 nmol/L, p = 0.039), and fivefold in bacteremic vs. non-bacteremic pneumonia (0.40 vs. 0.08 nmol/L, p = 0.02). Proadrenomedullin > 0.16 nmol/L showed 100 % sensitivity (95 % CI 39.8 – 100.0) and 70 % (95 % CI 58.7 – 79.7) specificity for bacteremia. Copeptin showed no added-value.
Proadrenomedullin seems a reliable and available predictor for complicated CAP, and could therefore help the physician with the decision to hospitalize, and choose the antibiotics administration route. Larger studies are needed.
Community-acquired-pneumonia (CAP) is the leading cause of child mortality worldwide [1]. The decision to treat with intravenous antibiotics and to hospitalize will depend on the severity of the disease and the risk of complications such as sepsis, empyema or abscess. Proadrenomedullin (ProADM) and copeptin (CoPEP) are peptides co-synthesized together with adrenomedullin and vasopressin in endothelial cells and pituitary gland respectively. These peptides have vaso-active, immune modulating, and metabolic properties. They are increased in sepsis, but they have a short half-life. ProADM and CoPEP are more stable and easier to measure than the active hormones [2, 3].
Performance of proadrenomedullin, C-reactive protein, and white blood cell count, for predicting bacteremic pneumonia. ROC area: Receiver-Operator Characteristic area under the curve for sensitivity and 1-specificity to predict bacteremic pneumonia; CRP: C-reactive protein; WBC: white blood cell; ProADM: proadrenomedullin
These novel biomarkers seem useful in predicting severity and complications in severe pneumonia in adults [4–6], but very few studies have explored the predictive value of these markers in children [7, 8].
Our objective was to assess ProADM and CoPEP's diagnostic accuracy for predicting complications in a cohort of children with community-acquired pneumonia (CAP).
Population and setting
We performed a secondary analysis of a prospective cohort study on biomarkers of pediatric pneumonia [9], including children aged 0 to 16 years presenting to the pediatric emergency department of three tertiary hospitals (Geneva, Lausanne, and Sion) with CAP, defined as fever (>38 °C), cough, tachypnea, and a radiographic lung infiltrate. Children with chronic heart, lung, or neurological diseases were excluded. A venous blood sample was drawn from each child for white blood cell count, C-reactive protein, blood culture (one sample), and subsequently from those with a clear-cut diagnosis of complicated or uncomplicated CAP, we also measured ProADM and CoPEP. Every child had a chest X-ray and, if a pleural effusion was present, a pleural liquid sample was drawn and sent for culture. We defined the diagnosis of "complicated CAP" as CAP with bacteremia (positive blood culture) or empyema (positive pleural culture). CAP with simple pleural effusions without empyema, was considered as "uncomplicated CAP". The three hospitals ethics committees approved this sub-study within the main pneumonia study [9], (Geneva, Vaud, and Valais states' Human Research Ethics Committees http://www.swissethics.ch/eks_e.html) and participants' parents or teenage patients provided informed written consent
Serum samples were immediately stored at −80 °C. ProADM and CoPEP values were determined using TRACE (time-resolved amplified cryptase emission) technology with the B.R.A.H.M.S. Kryptor Compact pro-ADM and Copeptin® (Brahms, Hennigsdorf, Germany). White blood cell counts (WBC) with differential (Band neutrophil percentage) and C-reactive protein (CRP) had already been performed in all children. The laboratory team who performed ProADM and CoPEP was blinded to the clinical data.
Using STATA 11.0 (Texas, USA) we analyzed baseline demographic and clinical characteristics expressed as percentages for categorical data, and median with interquartile ranges (IQR) for continuous data due to their non-normal distribution. Statistical associations were assessed using a chi-square test or Fisher exact test for categorical data, and a student's t-test or Wilcoxon-Mann–Whitney rank-sum test for continuous data; and multiple logistic regression using odds-ratios (adjusting for age, sex, previous medication and pneumococcal vaccination) was used to identify variables (ProADM, CoPEP, etc.) independently associated with the outcome variable, namely the cases of complicated CAP. Diagnostic performance was expressed through sensitivity, specificity, positive and negative predictive values (PPV and NPV), positive and negative likelihood ratios (LR+ and LR-) with 95 % Confidence Intervals (95 % CI), and receiver-operator characteristic with area under the curve (AUC). STARD, the Standard Reporting for Diagnostic studies was used, and its checklist is provided in Additional file 1.
We analyzed 88 samples from children meeting the inclusion criteria for CAP. These children were included from January 2008 to September 2010. Among these 88 children with CAP, eleven (12.5 %) presented with complicated CAP, (9 empyema, 4 bacteremia, and 2 with both complications). The pathogens isolated in blood and empyema cultures were all S.pneumoniae. The comparison between the two groups (complicated vs. uncomplicated CAP) showed no significant differences for baseline characteristics: age (median 3.1 years, IQR 1.81 – 5.76), sex, daycare attendance, passive tobacco exposure, and pneumococcal vaccination (p > 0.05).
Regarding the main objective, children with bacteremic pneumonia (n = 4) or empyema (n = 9) showed a general statistical association with ProADM (logistic regression p = 0.007 and 0.036 respectively), but not with CoPEP (p > 0.05). We found a significant difference in ProADM median values in complicated cases: complicated vs. uncomplicated (0.18 vs. 0.08 nmol/L, p = 0.039) and bacteremia vs. no-bacteremia (0.40 vs. 0.08 nmol/L, p = 0.02), as shown in the boxplot of Additional file 2.
This shows a twofold increase for complicated and a fivefold increase for bacteremic pneumonia. On the contrary, CoPEP did not distinguish complicated from uncomplicated CAP (p = 0.95).
The diagnostic accuracy of these biomarkers in predicting complicated CAP was analyzed and compared with classical biomarkers (WBC, band neutrophils, CRP). We found an optimal cut-off at 0.16 nmol/L for ProADM with 100 % sensitivity (95 % CI 39.8 – 100.0) and 70 % (95 % CI 58.7 – 79.7) and 10 pmol/L for CoPEP with a specificity of 67.5 % (95 % CI 56.1–77.6 %), but a low sensitivity 50 % (6.8–93.2 %). Table 1 shows that ProADM with a 0.16 nmol/L cut-off was very efficient to rule out bacteremia (sensitivity and NPV = 100 %, LR- 0.14 [0.01–2.00]), as accurate as CRP (>100 mg/L) and better than band neutrophils (>1.5 G/L) or leukocytosis (>15 G/L). ProADM >0.16 nmo/L, with a specificity of 70 % for bacteremia, was as accurate as band neutrophils, or CRP and better than leukocytosis to rule it in. With an overall ROC AUC of 0.85, the accuracy of ProADM was comparable to CRP for the diagnosis of bacteremia, as shown in Fig. 1. In contrast, CoPEP did not perform as well to exclude or confirm complicated CAP.
Table 1 Performance of proadrenomedullin, copeptin, C-reactive protein, white blood cell and band neutrophils (band cells) counts, for predicting "complicated" (with empyema or bacteremia) and "bacteremic"community-acquired pneumonia
This secondary analysis of 88 children with CAP supported the hypothesis that ProADM strongly predicts serious complications of pediatric community-acquired pneumonia (CAP), such as bacteremia and empyema. CoPEP on the contrary did not show such performances for predicting complicated CAP in our small population, but should be retested in larger samples.
Diagnostic performances of ProADM seem excellent, especially to rule-out bacteremia (sensitivity 100 %), and as accurate as classical markers (WBC, Band neutrophils, and CRP) with regards to specificity. Only true complications, such as bacteremia or empyema, seem to cause a significant elevation of ProADM above 0.16 nmol/L.
Compared to similar studies, Renaud et al. [6] showed that ProADM in elderly patients improved the prediction of early admission to ICU for severe CAP. In their study, ProADM showed a sensitivity of 95.0 % at a cut-off value of 0.75 nmol/L, and a specificity of 81.0 % at a cut-off value of 2.0 nmol/L.
One pediatric study by Sardà Sanchez et al. [8] showed that ProADM could predict simple pneumonia versus pneumonia with complications (2.32 vs. 1.18 nmol/L, p = 0.014) or pleural effusion (2.94 vs. 1.14, p < 0.001), but only fifty patients were included in this study, including ten with complications, of which seven with pleural effusions. Another pediatric study by Michels et al. [7] concluded that ProADM also predicts capillary damage, leakage and risk of shock in hemorrhagic dengue and dengue shock, showing that these lesions similar to sepsis can be predicted by this marker in non-bacterial sepsis-like syndromes.
Initially a marker of severity in non-infectious diseases such as stroke, CoPEP also seemed promising as a prognostic marker in CAP. This was suggested by Katan et al.'s review on adults with ventilator-associated pneumonia [5], and in a Swiss study on lower respiratory tract infections by Müller B et al. [10]. In the latter, CoPEP levels were significantly lower in survivors. However, in our study CoPEP did not show any added value as a predictor for complicated pediatric CAP, but the sample size may limit such conclusions. This could also be due to the low prevalence of severe CAP in our population compared to that of intensive care units in these studies, and the absence of mortality, even in cases with bacteremia and empyema. This hypothesis should be tested in future studies among children with ventilator associated pneumonia or sepsis.
A few limitations need to be stated: the design of this study was a secondary analysis of a larger study focused on the etiology of childhood CAP, with selection of samples with typical characteristics rather than random selection, implying a slight risk of selection bias. Although most statistical analyses seem coherent and logical compared to other studies, the design of this study did not include a sample size calculation, so that the significance levels could be inaccurate in small groups. The laboratory team who performed ProADM and CoPEP was blinded to the clinical data, reducing the risk of bias.
In conclusion, we found that ProADM, in contrast to CoPEP, seems to be an interesting marker of complicated CAP, very similar to CRP in sensitivity and specificity. It could therefore help the physician with the decision to hospitalize and choose the antibiotics administration route. Larger studies should assess the promising performances of ProADM in pneumonia and other serious pediatric infections, as well as further comparisons with CRP and Procalcitonin.
Black RE, Cousens S, Johnson HL, Lawn JE, Rudan I, Bassani DG, et al. Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet. 2010;375(9730):1969–87.
Morgenthaler NG, Struck J, Alonso C, Bergmann A. Measurement of midregional proadrenomedullin in plasma with an immunoluminometric assay. Clin Chem. 2005;51(10):1823–9.
Morgenthaler NG, Struck J, Alonso C, Bergmann A. Assay for the measurement of copeptin, a stable peptide derived from the precursor of vasopressin. Clin Chem. 2006;52(1):112–9.
Christ-Crain M, Morgenthaler NG, Stolz D, Müller C, Bingisser R, Harbarth S, et al. Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia [ISRCTN04176397]. Crit Care. 2006;10(3):R96.
Katan M, Muller B, Christ-Crain M. Copeptin: a new and promising diagnostic and prognostic marker. Crit Care. 2008;12(2):117.
Renaud B, Schuetz P, Claessens YE, Labarere J, Albrich W, Mueller B. Proadrenomedullin improves Risk of Early Admission to ICU score for predicting early severe community-acquired pneumonia. Chest. 2012;142(6):1447–54.
Michels M, Djamiatun K, Faradz SM, Koenders MM, de Mast Q, van der Ven AJ. High plasma mid-regional pro-adrenomedullin levels in children with severe dengue virus infections. J Clin Virol. 2011;50(1):8–12.
Sarda Sanchez M, Hernandez JC, Hernandez-Bou S, Teruel GC, Rodriguez JV, Cubells CL. Pro-adrenomedullin usefulness in the management of children with community-acquired pneumonia, a preliminar prospective observational study. BMC Res Notes. 2012;5:363.
Chappuy H, Keitel K, Gehri M, Tabin R, Robitaille L, Raymond F, et al. Nasopharyngeal carriage of individual Streptococcus pneumoniae serotypes during pediatric radiologically confirmed community acquired pneumonia following PCV7 introduction in Switzerland. BMC Infect Dis. 2013;13:357.
Muller B, Morgenthaler N, Stolz D, Schuetz P, Müller C, Bingisser R, et al. Circulating levels of copeptin, a novel biomarker, in lower respiratory tract infections. Eur J Clin Investig. 2007;37(2):145–52.
We wish to thank Florence Hugon, for her contributions as data manager, research nurse, for patient and samples follow-up and very accurate coordination of the whole process. We wish to thank Kristina Keitel, MD MPH, and Veronica Maspoli, MD, for their contributions in the initial cohort design, data collection and sample acquisition, and Lynda Vandertuin, MD, for her contribution with patient clinical follow-up.
Pediatric Emergency Division, Geneva University Hospitals (HUG), Rue Gabrielle Perret-Gentil 6, 1211, Geneva 14, Switzerland
Gabriel Alcoba, Sergio Manzano, Laurence Lacroix, Annick Galetto-Lacour & Alain Gervaix
Tropical & Humanitarian Medicine Division, Geneva University Hospitals (HUG), Rue Gabrielle Perret-Gentil 6, 1211, Geneva 14, Switzerland
Gabriel Alcoba
Sergio Manzano
Laurence Lacroix
Annick Galetto-Lacour
Alain Gervaix
Correspondence to Gabriel Alcoba.
The following author contributed as follows: GA data acquisition, statistical analysis and interpretation, manuscript writing and review coordination; GA and SM equally for study interpretation and manuscript reviews (first co-authorship); LL and AGL result interpretation, manuscript review; AG: study conception, coordination, design, interpretation, manuscript review. All authors read and approved the final manuscript.
Gabriel Alcoba and Sergio Manzano contributed equally to this work.
STARDchecklist_wordversion. (DOC 48 kb)
Box plot. (PPTX 56 kb)
Alcoba, G., Manzano, S., Lacroix, L. et al. Proadrenomedullin and copeptin in pediatric pneumonia: a prospective diagnostic accuracy study. BMC Infect Dis 15, 347 (2015). https://doi.org/10.1186/s12879-015-1095-5
Pediatric Emergency Department
Band Neutrophil


text:
Espantos de agosto, escrito originalmente en 1980, es el sexto del compendio de doce cuentos escritos y redactados por Gabriel García Márquez a lo largo de dieciocho años, que conforman el libro llamado Doce cuentos peregrinos.

Resumen
Una familia decide viajar a una región de Italia para visitar a un escritor. Cuando llegan al pueblo, se les hace difícil encontrar la casa y les preguntan a varias personas, hasta que una señora  les indica dónde se halla, y esta les advirtió que en ese castillo asustaban. Como no creían en los fantasmas se lo tomaron como una broma, incluso se rieron de las palabras de la lugareña por su credulidad. Sin embargo los dos niños de la familia se entusiasman ante la idea de conocer a un fantasma en cuerpo y alma. Finalmente llegan a la casa que es un Castillo, donde los estaba aguardando su amigo escritor para el almuerzo. Les cuenta la historia del hombre que construyó el castillo en la época del Renacimiento, quien sacrifico a su mujer. El anfitrión les afirma y advierte que el espíritu aún vaga por el castillo a medianoche. Después de la comida, se dedican a explorar el castillo, llegando a la habitación de Ludovico, que atrajo especialmente su atención ya que esta habitación estuvo intacta desde hace siglos. Después van a la plaza de la aldea y más tarde, tras volver al castillo y cenar, deciden quedarse a pasar la noche. Se duermen tranquilos en sus habitaciones, pero en la mañana se despierta el marido junto a su mujer en la habitación del fantasma Ludovico , que no era la que les habían asignado la noche anterior.

Referencias
 García Márquez, Gabriel (1996). Cuentos: 1947-1992. Norma. ISBN 9580429391.
 García Márquez, Gabriel (1992). Doce cuentos peregrinos. Sudamericana. ISBN 9500707756.

Cuentos de Gabriel García Márquez

redpajama_set_name: RedPajamaWikipedia


Arag seletron 5 way nozzle body. Available from 1/2" through to 3/4". Sold with VITON or TEFLON seal pack.
IMPORTANT - TEFLON are better for agricultural chemicals and fertilizers. When fitting the seletron motor to the body, it MUST be set to a torque of 4nm exactly. It is advised to buy a torque tool to reset motor to body if replacing seals.


text:
The evolution of the culture of risk linked to an uncertain future
An important question raised by the cultural theory of risk is the idea of a fundamental continuity between our present culture of risk and earlier periods of (pre)modernity (Wilkinson, 2001). While theorists of risk society (Beck, 1986/1992), as was mentioned, emphasize the novelty of our situation related to contemporary technological hazards, the cultural theory states that humanity has always been faced with risks of uncertain future, even annihilation. Risk taking and risk aversion ("shared confidence and shared fears") are part of a narrative about organizing human social relations (Douglas & Wildavsky, 1982, p. 8). Humans choose their risks together with their social institutions, which are commonly used to order their universes. Cultural theory explains the selection of dangers among traditional and modern people within the same framework.
Note: See source document for full reference.
Cultural Factors: Social networks
Types of Actors Concerned: Non-active citizens, National civil protection body, Local authorities, Active citizens, Entrepreneurs, Media, Government, National research bodies, Red Cross, NGOs, Military, Law enforcement agencies, Healthcare and emergency services, European Civil Protection Mechanism, UN and other international organisations, All types of actors
Develop risk assessments methodologies, which consider cultural factors, the manner in which people cognitively process information and which employ a gender perspective
Deliverable D4.1 "Mapping risk perception concepts in the context of disasters" (page 35)


text:
Israeli Entrepreneurs To Host Hackathon For Benefit Of Holocaust Survivors
By NoCamels Team April 08, 2018
April 8, 2018 | Israeli entrepreneurs are set to host a hackathon next month for the benefit of Holocaust survivors in Israel and across the world. The 36-hour event, slated for May 10 and 11, is hosted by TLV Starters, the organization behind the book "Startup Guide Tel Aviv." The group said the event, dubbed "Spark Hackathon," is aimed at harnessing "the power of [the] 'Startup Nation' to make an impact and create applicable and feasible solutions for the benefit of Holocaust-related issues." Holocaust survivors, the group says, face a number of daily challenges, including financial, psychological, health, social, and others." In Israel, some 50,000 Holocaust survivors live below the poverty line, relying on donations and aid organizations to survive. In the US, a third of the remaining 100,000 survivors live in poverty with a majority living on less than $23,000 a year. Noting a "very concerning wave of Holocaust and related denial of historical events," TLV Starters says the Israeli high-tech sector "holds incredible resources of manpower and know-how" and "can do so much more to support this unique Israeli and Jewish challenge." The hackathon will aim to "find and create feasible solutions for challenges in education, remembrance, and quality of life of Holocaust survivors," as well as establish a platform that will enable collaboration and partnerships between companies and organizations." TLV Starters, founded by Erez Gavish and Natan Leibzon, promises thousands of shekels in prizes for the winner. The initiative is led Gavish, Leibzon, Anat Greemland and Alon Rapaport and has the support of leading Israeli venture capitalists and entrepreneurs, as well as the Foundation for the Benefit of Holocaust Victims in Israel, Tel Aviv University, the Tel Aviv Stock Exchange, and tech giant Microsoft. Israel marks Holocaust Memorial Day, or Yom Hashoah, on April 12 this year.


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A management buyout (MBO) is a form of acquisition in which a company's existing managers acquire a large part, or all, of the company, whether from a parent company or individual. Management-, and/or leveraged buyout  became noted phenomena of 1980s business economics. These so-called MBOs originated in the US, spreading first to the UK and then throughout the rest of Europe. The venture capital industry has played a crucial role in the development of buyouts in Europe, especially in smaller deals in the UK, the Netherlands, and France.

Overview
Management buyouts are similar in all major legal aspects to any other acquisition of a company. The particular nature of the MBO lies in the position of the buyers as managers of the company and the practical consequences that follow from that. In particular, the due diligence process is likely to be limited as the buyers already have full knowledge of the company available to them. The seller is also unlikely to give any but the most basic warranties to the management, on the basis that the management know more about the company than the sellers do and therefore the sellers should not have to warrant the state of the company.

Some concerns about management buyouts are that the asymmetric information
possessed by management may offer them unfair advantage relative to current owners. The impending possibility of an MBO may lead to principal–agent problems, moral hazard, and perhaps even the subtle downward manipulation of the stock price prior to sale via adverse information disclosure, including accelerated and aggressive loss recognition, public launching of questionable projects, and adverse earning surprises. These issues make recovery by shareholders who bring suit challenging the MBO more likely than challenges to other kinds of mergers and acquisitions.
Naturally, these corporate governance concerns also exist whenever current senior management is able to benefit personally from the sale of their company or its assets. This would include, for example, large parting bonuses for CEOs after a takeover or management buyout.

Since corporate valuation is often subject to considerable uncertainty and ambiguity, and since it can be heavily influenced by asymmetric or inside information, some question the validity of MBOs and consider them to potentially represent a form of insider trading.

The mere possibility of an MBO or a substantial parting bonus on sale may create perverse incentives that can reduce the efficiency of a wide range of firms—even if they remain as public companies. This represents a substantial potential negative externality. The managers of the target company may at times also set up a holding company for the purpose of purchasing the shares of the target company.

Purpose

Management buyouts are conducted by management teams as they want to get the financial reward for the future development of the company more directly than they would do as employees only. A management buyout can also be attractive for the seller as they can be assured that the future stand-alone company will have a dedicated management team thus providing a substantial downside protection against failure and hence negative press. Additionally, in the case the management buyout is supported by a private equity fund (see below), the private equity will, given that there is a dedicated management team in place, likely pay an attractive price for the asset.

Financing

Debt financing
The management of a company will not usually have the money available to buy the company outright themselves. They would first seek to borrow from a bank, provided the bank was willing to accept the risk. Management buyouts are frequently seen as too risky for a bank to finance the purchase through a loan.  Management teams are typically asked to invest an amount of capital that is significant to them personally, depending on the funding source/banks determination of the personal wealth of the management team.  The bank then loans the company the remaining portion of the amount paid to the owner.  Companies that proactively shop aggressive funding sources should qualify for total debt financing of at least four times (4X)  cash flow.

Private equity financing
If a bank is unwilling to lend, the management will commonly look to private equity investors to fund the majority of buyout. A high proportion of management buyouts are financed in this way. The private equity investors will invest money in return for a proportion of the shares in the company, though they may also grant a loan to the management. The exact financial structuring will depend on the backer's desire to balance the risk with its return, with debt being less risky but less profitable than capital investment.

Although the management may not have resources to buy the company, private equity houses will require that the managers each make as large an investment as they can afford in order to ensure that the management are locked in by an overwhelming vested interest in the success of the company. It is common for the management to re-mortgage their houses in order to acquire a small percentage of the company.

Private equity backers are likely to have somewhat different goals to the management. They generally aim to maximise their return and make an exit after 3–5 years while minimising risk to themselves, whereas the management rarely look beyond their careers at the company and will take a long-term view.

While certain aims do coincide—in particular the primary aim of profitability—certain tensions can arise. The backers will invariably impose the same warranties on the management in relation to the company that the sellers will have refused to give the management. This "warranty gap" means that the management will bear all the risk of any defects in the company that affect its value.

As a condition of their investment, the backers will also impose numerous terms on the management concerning the way that the company is run. The purpose is to ensure that the management run the company in a way that will maximise the returns during the term of the backers' investment, whereas the management might have hoped to build the company for long-term gains. Though the two aims are not always incompatible, the management may feel restricted.

The European buyout market was worth €43.9bn in 2008, a 60% fall on the €108.2bn of deals in 2007. The last time the buyout market was at this level was in 2001 when it reached just €34bn.

Seller financing
In certain circumstances, it may be possible for the management and the original owner of the company to agree a deal whereby the seller finances the buyout. The price paid at the time of sale will be nominal, with the real price being paid over the following years out of the profits of the company. The timescale for the payment is typically 3–7 years.

This represents a disadvantage for the selling party, which must wait to receive its money after it has lost control of the company. It is also dependent, if an earn-out is used,  on the returned profits being increased significantly following the acquisition, in order for the deal to represent a gain to the seller in comparison to the situation pre-sale. This will usually only happen in very particular circumstances. The optimum structure would be to convert the earn-out to contracted deferred consideration which has compelling benefits for the seller as it legally fixes the total future amount paid to them. It's paid like a quarterly annuity, and then the seller needs to secure the annuity by taking out a deferred consideration surety guarantee from an independent surety institution. The direct beneficiary of the surety is the seller and should the sold firm become insolvent, following its sale, with any outstanding deferred payments due the seller, then the surety will pay the money to the vendor on the purchaser's behalf.

The vendor agrees to vendor financing for tax reasons, as the consideration will be classified as capital gain rather than as income. It may also receive some other benefit such as a higher overall purchase price than would be obtained by a normal purchase.

The advantage for the management is that they do not need to become involved with private equity or a bank and will be left in control of the company once the consideration has been paid.

Examples
A classic example of an MBO involved Springfield Remanufacturing Corporation, a former plant in Springfield, Missouri, owned by Navistar (at that time, International Harvester) which was in danger of being closed or sold to outside parties until its managers purchased the company.

In the UK, New Look was the subject of a management buyout in 2004 by Tom Singh, the founder of the company who had floated it in 1998. He was backed by private equity houses Apax and Permira, who now own 60% of the company. An earlier example of this in the UK was the management buyout of Virgin Interactive from Viacom which was led by Mark Dyne.

The Virgin Group has undergone several management buyouts in recent years. On September 17, 2007, Richard Branson announced that the UK arm of Virgin Megastores was to be sold off as part of a management buyout, and from November 2007, will be known by a new name, Zavvi. On September 24, 2008, another part of the Virgin group, Virgin Comics underwent a management buyout and changed its name to Liquid Comics. In the UK, Virgin Radio also underwent a similar process and became Absolute Radio.

In Australia, another group of music and entertainment stores were subject to a management buyout in September 2009, when Sanity's owner and founder, Brett Blundy, sold BB Retail Capital's Entertainment Division (including Sanity, and the Australian franchises of Virgin Entertainment and HMV) to the company's Head of Entertainment, Ray Itaoui. This was for an undisclosed sum, leaving Sanity Entertainment to become a private company in its own right.Hitman is a stealth video game series developed by the Danish company IO Interactive, which was previously published by Eidos Interactive and Square Enix. IO Interactive remained a subsidiary of Square Enix until 2017, when Square Enix started seeking sellers for the studio, IO Interactive completed a management buyout, regaining their independent status and retaining the rights for Hitman'', in June 2017.

See also
 Takeover
 Management buy-in
 Leveraged buyout - includes secondary buyout
 Envy ratio

References

External links
 Definition of management buyout
 Definition of buy-in management buyout

Corporate finance
Management
Private equity


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Tesla : Jeff Keith Interview – Jan 13, 2005
January 15, 2005 by Jarrod Vrazel
ZRock exclusive! Tesla : Jeff Keith Interview
by Jarrod Vrazel : zrock.com
Photo by Lynda Niemeier
ARF founders Tony and Elaine La Russa with Tesla
and a few four-legged friends at ARF Rocks!
Tesla headlined an evening of rock and roll at Tony La Russa's Animal Rescue Foundation's (ARF) ARF Rocks! fundraiser on Friday, January 7, 2005 at the Dean Lesher Regional Center in Walnut Creek, California. You can help this wonderful cause by donating online
I spoke with Jeff yesterday and discussed ARF Rocks! and Tesla's upcoming Tesla : Five Man Acoustical Jam 2005 Tour .
ZRock: Hi Jeff, I'd like to get some comments regarding Tony La Russa's Animal Rescue Foundation (ARF) and your ARF Rocks! show last week. Maria Brunner from Insight Management sent us a few wonderul photos of the band with Tony and Elaine La Russa and some of the pups. I wanted to get a little feedback from you about the event and how you got involved with ARF Rocks!
Jeff: The way we got involved is through someone we are acquainted with, Tony Lopez. He had gotten involved with ARF and Tony La Russa, and he knew the story about me finding the dog. In November 2003, I went down to a Raiders game – I never made it into the game, but I came home with an awesome friend. His name is Okie – he was just some mutt down there as I was walking to get in line. So Tony Lopez told Tony La Russa the story and says, Man, if you're looking for some people to play in your benefit show, Jeff Keith and the guys in Tesla are right up your alley. He told him the Okie story, and that's how we got involved. Tony La Russa and his wife, Elaine, are awesome people. I can't believe the quality of these people. they're just great people and they care about animals. I'm a big animal lover, as well as all of us in the band – we're big animal lovers.
ZRock: Maria told me that she met Okie at the show. Did you have some pictures taken with him as well?
Jeff: Yes, we had some pictures taken with Tony and everybody. Okie's a star now! He's right here on the floor listening to me do this interview right now. He's a big star and he doesn't even know it.
ZRock: I believe I've got Okie on the ZRock home page with the band and Tony and Elaine La Russa – is he goldish with a blue collar?
Jeff: Yes, he is. I ll have to check that out – ZRock.com – I'm gonna check that out.
ZRock: Okie's got a big smile on his face. Brian's face is covered up a little bit – he's holding up two pups.
Jeff: Those are Brian's dogs – Jack Russell Terriers.
ZRock: Troy is holding a little child wearing a red shirt.
Jeff: That's his stepdaughter. He just got married last year. She's a little cutie – Skylar is her name. Elaine La Russa also had a little silver dog there. She had this little puppy that they rescued that was going to get put to sleep. It was this little bitty tiny silver mutt – I don't even know what kind of dog it is. When I say mutt – mutts are my favorite dogs – so I'm not saying in a bad way. It was a little silver mutt, and it was so precious. It was so tiny that you may not be able to see it in the picture.
ZRock: Do you take Okie out on the road with you?
Jeff: I don't take Okie on the road. I have a house sitter – I have quite a few animals. I've got a one eyed pony, a couple goats, a bunch of cats, and a couple other dogs. I've got a lot of animals and a lot to take care of, so I have someone take care of them for me. He's too big to be on the bus anyway. On the last leg with the Scorpions, Brian brought his dogs for quite a well. It was fun walking them three or four times a day. I get off on walking dogs. I know it sounds funny, but I love to see them relieve themselves and just smell all the scents. I really get a kick out of it. It was fun walking the dogs. I'd love to take Okie out there, but he's too much of a high-strung dog to be keeping him penned up on the bus.
When we went out on tour with Poison years ago, Brett Michaels had this big dog – like the ones that pull the Eskimos on their sleds. This poor dog – I felt so sorry for him – sometimes he had to use the bathroom on the bus. I would ask Brett permission to go walk his dog for him – I knew he wanted to get out of there. It made me realize that I should never bring my dog out on the road. Especially a big dog – Okie's a pretty big boy. With Brian's smaller dogs, it's easier – they can sit on somebody's lap when people are sitting in the bus. With big dogs it's a lot tougher. Plus, they're around surroundings where they're getting too many handouts – you can't keep an eye on them. Everybody wants to slip them a little piece of something, and next thing you know, they're sick. Brian had a problem with that a couple of times. His dogs would be sick, and he really didn't know from what.
ZRock: Plus, if you keep them in their home environment, you know they're safe and sound.
Jeff: Exactly! They love taking care of the ranch.
ZRock: From what I've heard, it sounds like you had a great time with Pat Travers and some of the other guys at ARF Rocks!
Jeff: Oh, yes. That was awesome! We jammed a Stones song at the end. And Carmine Appice – we got it official from Carmine – we've always wondered: Is it Carmine App-a-see or Carmine A-peace? He said his brother, Vinnie, goes by Vinnie App-a-see and he goes by Carmine A-peace. It was fun jamming with him, Pat Travers and his band, and Brad Gillis from Night Ranger. We were just rockin out for a great cause. Everybody's faces were full of smiles. It was just awesome. It was the first time I've really got to do something like that – a benefit show for animals. I was so thrilled, and I ll be thrilled to do it again.
We've got another benefit coming up – for people – the people that caught in the Station club fire in Rhode Island.
ZRock: It's great that you ll be helping out the Station Family Fund. Great White has done a lot of shows to help out that cause. I saw Tesla with Great White back in 89 on the Double Header Tour at City Coliseum in Austin. It was a great show back then – it's great to see you still out on the road.
Jeff: It's awesome to be out on the road. We are so grateful to be back together – we had split up for six or seven years. And to have a new record out that we're all happy with and it's doing well. It's a great thing – we're very grateful.
ZRock: I know that Tesla was missed when you weren't playing. Some of the Sofa King and other shows kind of filled in a little, but they weren't quite the same.
Jeff: Sofa King and Bar 7 for me and Tommy were just holding up because we didn't have Tesla. I didn't want to be involved with music, I thought, after Tesla broke up. If I couldn't do it with the guys, I didn't want to do it anymore. But I really had a passion for it and was just kinda throwing it aside for the time being. And then Tommy approached me after a few years and said, Hey, I want to write music with you again. So we did that because there was no Tesla. As a matter of fact, we played the Station in Providence three times. We've been to the place, and we're very familiar with it. Bar 7 was cool, but it was just a filler. It's great to be back with the guys and to be playing with them. I like the pictures you have – they're all smiles.
ZRock: Even the animals are smiling, which is really cool.
Jeff: That's awesome. You know, I have a broken wrist in those pictures. On Christmas Day, we successfully threw a surprise birthday party for a buddy of mine who was born on Christmas. He never gets a birthday party. When he told me that last year, I knew we had to throw this guy a surprise party. We usually go dirt bike riding and stuff, and we should've done that. But we went snow boarding – I've done it once before and didn't do too bad. But we went on this man-made snow and ice and I went down and broke my wrist hard. I'm sitting thinking, Oh God, I've got to play this gig for Tony La Russa. I'm looking so forward to it. So I had surgery on that Monday and we played on Friday. Monday and Tuesday were painful, but once we got to Wednesday, I knew I was gonna be able to do this gig. I was so glad to. Like I said, it's for animals, and I just love doing things for animals. I'm the kind of guy that my eyes are always peeled – I'm looking for the helpless animals. I ll bring them home sometimes and I ll nurse them. I've gone as far as getting them fixed and getting them all their shots, and then finding a home for them.
ZRock: It seems that some people dump off animals and let someone else worry about them. If no one else worries about them, they're gone.
Jeff: I know. So I'm the guy who goes, Well, I'm here to worry about them. I'm glad to be a part of it. It was really good for the soul. I'm looking forward to doing it again. I told Tony and Elaine that next year we want to do it again.
ZRock: Tesla have just announced the Five Man Acoustical Jam 2005 tour. Are you ready for that?
Jeff: Yes, we're looking forward to that. That acoustic record was so successful for us, and we only played five acoustic shows – Philadelphia was the one we recorded – back in 1990 when we were on tour with Motley Crue. That was really succesful for us – it was our most successful record. We're looking forward to going and hitting a bunch of cities that never got to see that live. When we got back together after our reunion show, we did some West Coast dates – Vegas, LA, Anaheim and a few places like that. We still haven't got to go across the country with it, so we're really looking forward to that and we hope the people are, too.
ZRock: I'm pretty sure they will be. I saw you play in Austin with the Scorpions and at Verizon Wireless in Houston earlier last year and several tours before that. It was a nice treat when there were acoustic sets in the middle of the show. I know that people in Texas haven't had the benefit of the full acoustic show unless they watch the DVD.
Jeff: We plan on bringing it to them, man. We're looking forward to it.
ZRock: I appreciate everything you've done for the Animal Rescue Foundation and for helping out on the ARF Rocks! benefit. Whenever you get on stage, there's still work to be done, and it's nice when you can have your work go towards the benefit of this great cause.
Jeff: I appreciate that, Jarrod. Thanks, man. Like I said, it's a great feeling and I look forward to doing it again.
ZRock: Best wishes on the rest of the year. We do all we can do help spread the Tesla word. ZRock was the first to have the Into the Now artwork, and people were really excited to see something new. It's nice to see the true musicians still making music out there.
Jeff: Right on. Thanks, Jarrod, I appreciate that very much. That means a lot coming from you.
ZRock: We ll also being working with Tony and ARF to try to get some online donations going for the cause from the people who aren't able to attend ARF Rocks! in person.
Jeff: Right on – I'd like to give to that, too. I ll be looking forward to that.
ZRock:Thanks for your time – we ll see you on the road.
Funds raised from this fantastic fundraiser will used by ARF's Adoption and Education Center to save the lives of loving dogs and cats who have run out of time at public shelters. ARF gives another chance at life to dogs and cats who would have otherwise be killed. ARF provides the care and attention they need, including spay or neuter surgery, until ARF finds them a new home of their own.
ARF's People Connect programs strengthen the human animal bond for the elderly; residents of assisted living centers, teens at juvenile hall, high school students, grade school students and young children through programs that are national models of excellence. ARF programs allow people to experience the unconditional love and acceptance of dogs and cats. People rescuing animals… animals rescuing people.
: : : : :
Tesla ARF Rocks! concert photos
Animal Resue Foundation
Donate online to ARF
Tesla official site
Tesla : Five Man Acoustical Jam 2005
Tesla Houston concert photos – June 14, 2004
Tesla bio
listen to Tesla free samples / download from iTunes
Buy Tesla now from Amazon
Filed Under: Interviews, Tesla
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