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Posted by: calloftheandes | July 19, 2013
Not One Tear Wasted for Woman Recalling Hardships as Missionary Kid in Ecuador
Story by Ruth Pike and Ralph Kurtenbach
Record my misery;
list my tears on your scroll—
are they not in your record?
—Psalm 56:8 (NIV)
Robbyn Booker
Returning to Ecuador after 40 years, Robbyn Booker has been thrilled by the "blessing of being able to come here and see what the Lord did with those tears that I shed." A child of evangelical missionaries, she grew up in the South American country during the 1960s.
Her former church in Quito, Iglesia Evangélica Iñaquito, has grown 20-fold and is still growing. The church, whose name translates as Iñaquito Evangelical Church, is now led by Ecuadorians rather than North American missionaries. Offering five services every Sunday, the congregation meets across from Radio Station HCJB's campus in Quito where her parents, Leonard and Imogene Booker, served in English-language broadcasting. The church is now sending workers around the world, including countries often closed to North American missionaries.
For Booker, the hardships of growing up as a foreigner in another country were definitely worthwhile. Originally from California, she arrived in Quito with her family in 1962 just prior to her 11th birthday. Producing programs for listeners around the world via international shortwave radio, her parents also responded to listeners who wrote to the station.
Typical programming included news and cultural shows followed by a short Bible message. Every Thursday after school, the children of the radio producers would sing Sunday school songs and perform skits for live radio and television, including a popular children's radio program called "Gospel Bells."
Booker also used to play the piano for church services at the Iñaquito church, whose congregation began decades ago in the home of Dr. Paul Roberts, founder of the mission's Hospital Vozandes-Quito. His wife, Barbara, who served as a nurse, held Bible studies known as "kids' clubs" in the couple's backyard.
Archive photo from an HCJB Global prayer album, circa mid 1960s.
For her family, the transition to life in Ecuador held its fair share of challenges—communicating with relatives for a start. During the 1960s, Radio Station HCJB aired Party Line which originally featured missionary families sending monthly greetings to their homelands where their loved ones could listen on shortwave. Some missionaries—but not the Bookers—used amateur band (ham) radio to keep in touch with home.
Daily life was an adjustment too. Shops were few and far between, prompting difficulties in buying even common conveniences, including shampoo.
Booker said that for the first four years, "every night I cried myself to sleep." However, a trip to the U.S. on home ministry assignment in 1965 involving visits to donors and family enabled her to see Ecuador as home and gave her a greater excitement for the work there.
In 1969 she began living in the U.S. In the ensuing decades, in spite of developing a successful career in banking, she declares, "I've always prayed, 'Please don't let this be my life.'" Then in 2006 a short-term voluntary trip to Ukraine reignited a longstanding interest in serving God overseas.
Robbyn Booker at Pan de Vida (Bread of Life) in Quito
However, the real push came in September 2012 when she was unexpectedly laid off. This news came as a shock for Booker, but not to her daughter who confessed, "I was praying for you to lose your job!" As she came to terms with this, she asked God, "Are you freeing me up?"
A few months later, she is now serving in Quito, Ecuador, as a working visitor in HCJB Global's human resources department. She speaks enthusiastically of the opportunity "to encourage the people … doing the work." She also volunteers at Pan de Vida (Bread of Life), a ministry begun in 2001 when a local businessman, Oscar Aguirre, shared God's Word and a breakfast with 20 people who had gathered in the carport of former HCJB Global missionaries David and Marilyn Tippett.
Life is never without its challenges, and unexpected health problems greeted her in Quito. Yet she is still able to declare confidently that "the Lord is in control and He has a purpose."
"I'm feeling so blessed to be here," she relates. "This makes it like the full circle." Seeing the growth of her former church and the continuing work of HCJB Global has given Booker a fresh perspective on the trials she experienced growing up in a different culture. Looking back on her childhood in Ecuador, she can genuinely say that "not one tear was wasted."
Have a half hour? Listen to "Christmas With The Bookers"
Archive photo shows the Bookers in the early to mid 1960s.
Posted in The Voice of Jesus in Our World | Tags: DX Partyline, expat living in the 1960s, Gospel Bells on HCJB, HCJB Global, HCJB Global Voice, Hospital Vozandes-Quito, missionary Barbara Roberts in Ecuador, missionary radio, MK or missionary kid, Pan de Vida in Quito, Psalm 56:8 (NIV), Radio Station HCJB
« Ecuadorian Beneficiaries of Clean Water System Now Training Haitians
Desperate Mountaintop Prayer Answered When Lost Tourist Is Rescued »
[…] Springs to be closer to family, including their son Gary who works at Focus on the Family and their daughter, Robbyn, who has served as a missionary to Spain and recently joined Reach Beyond as a […]
By: Veteran Broadcaster Leonard Booker Remembered for His Voice, Humor | Calloftheandes Weblog on February 12, 2016


June and moon pair perfectly to bring in the ideal romance with warm days and clear nights, just like Juniper and its essential oil, known as 'the mover of fluids' work wholly to get rid of the toxic remains and excess fluid in your system, so that you fall in love with yourself again and again.
Boasted as the best diuretics in Western Herbal Medicine and in Traditional Herbalism, Juniper berries and its essential oil are looked upon for treating various fluid retention diseases like congestion, sciatica, rheumatism, edema, swollen joints, urinary tract infections, lumbago, cystitis, obesity and respiratory conditions.
Hapusha is the Ayurvedic name of Juniper and is scientifically known as Juniperus communis. Juniper is held high in Ayurveda as one among the best detoxifying natural agent with its diuretic and diaphoretic properties for eliminating excess water deposits, toxic remains, uric acid, salt and fat deposits by promoting the frequency and quantity of sweating and urination.
Juniper berries are not real berries but are the female seed cones produced by many species of Junipers. It is an evergreen shrub that is found growing in the wild and can grow up to a height of 30 feet. Juniper is a native of the European Province, Asian subcontinent and few North American countries including Oregon and Texas.
Juniper was the notable symbol of Ashera, the Goddess of Fertility of the Canaanites. The mystical fragrance of Juniper was used as incense by the Scottish and Tibetans to keep away from demons and evil spirits. The first historical use of Juniper berries dates back to the Egyptian Papyrus from 1500 B.C.
The berries of the Juniperus communis species are used as a popular spice in the European cuisine for its unique flavor. It has been used in the treatment of leucorrhoea, scrofula and chest conditions in the traditional French medicine.
It was in ancient Greek medicine, Juniper berries were recorded for their medicinal uses before being stated as a culinary item. The aboriginal Americans used these berries for suppressing the appetite when they were hungry. Certain tribal populace used Juniper berries as female contraceptive agents.
Juniper berries were used as a substitute for long pepper and black pepper varieties by the primordial Romans. It was believed that Juniper berries enhanced physical endurance and vigor in athletes, for which it was used during many of the Olympic events by the people of Greece.
For its power to prevent infections and its antiseptic values, Juniper berries were used as a precautionary medicine during the Bubonic plague. These spicy little berries were used as a folklore remedy for treating urinary infection, chest congestion, stomach upset and warts. Juniper berries are also used as a flavoring agent in gin and other traditional food items.
The notable therapeutic properties of Juniper berry oil are diuretic, energizer, disinfectant, antiseptic, analgesic, carminative, diaphoretic, antibacterial, astringent, anti-rheumatic, antispasmodic, depurative, sudorific, vulnerary, tonic, rubefacient, calmative and stimulant.
The chemical components contributing to its varied remedial values are sabinene, a-pinene, b-pinene, camphene, myrcene, a-terpinene, a-phellandrene, y-terpinene, b-phellandrene, 1,4-cineole, p-cymene, bornyl acetate, terpinen-4-ol, caryophyllene along with a hint of borneol, limonene, linalool, nerol, linalyl acetate and camphor.
Ayurveda is unquestionably the Master and the Mother of the world of medicine and has given birth to various remedial sciences including Siddha, Unani, The Traditional Chinese Medicine, Homeopathy, Naturopathy, Allopathic, Chiropractic, Acupressure and much more.
The secret behind its majestic stand for about 5000 years is its holistic healing approach that aims in tracing and treating the root cause of an illness rather than its occasional symptoms. Ayurveda completely relies on natural remedies and Ayurvedic techniques for the treatment and the prevention of diseases to pave way for longevity.
The Indian mythology records the birth of Ayurveda as gift of Lord Brahma, the God of Creation to Acharya Dhanvantari, the Lord of Ayurvedic medicine and he was also adored as the Physician of Gods. Ayurveda is a prominent part of Atharvaveda, one of the 4 sacred books of the Hindu tradition of India.
Acharya Charaka and Sushruta added glory to Ayurveda with their greatest works namely Charaka Samhita and Sushruta Samhita, the renowned Ayurvedic encyclopedias. These noble books cover every medical practice from a C-section delivery to Plastic surgery. Everything aims at attaining holistic health, which is a combination of physical, psychological and spiritual wellness.
Ayurveda recommends a disciplined life for retaining absolute balance with nature. Ayurvedic philosophy states that everything in this universe is made up of five elements of nature viz., earth, water, air, fire and space.
Water represents blood and other fluids in the system, earth denotes bones and the muscular built up, air assists in the breathing mechanism, space is the soul/the spirit that dwells in and fire is in charge for body temperature and all other metabolic functions.
All the individuals on earth are created in a distinctive manner with a unique physical, mental and spiritual setup, determined by the individual constitution known as doshas. These dynamic energies are an array of the five fundamental elements of nature.
Vata dosha (air and space) is responsible for the functions of the nervous system, respiratory system and the circulatory system. Pitta dosha (fire and water) takes care of body temperature and metabolism. Kapha dosha (water and earth) and is in charge of the physique, reproductive health and sustenance.
Every person has a prevalence of any one dosha that determines one's persona, traits and behavioral patterns. Absolute balance between these doshas as per the Law of nature indicates health and imbalance of doshas leads to sickness.
Ayurveda recommends natural remedies including plant essential oils, herbal medications, yogasanas, meditation, prayers, simple physical exercises, Ayurvedic routine, Pranayama (yogic breathing practice), Panchakarma (five detoxification therapies), and certain other Ayurvedic treatments for nurturing natural balance between doshas.
It's time to take a look at the varied health benefits of Juniper berry oil in terms of physical, emotional and spiritual attributes.
Physical benefits: 'Face is the index of the mind' is a popular saying. In a much similar way, the human body showcases the sickness of the mind and the soul. Traditional healthcare experts say that every illness has certain underlying emotional and hereditary (tarpana) reasons behind to deal with. Talking with the patient about everything including their medical history, family, daily routine, lifestyle practices, behavioral patterns and every little thing that has an impact in their daily lives, can help in identifying the root cause of their sickness and in bringing a permanent solution to their health problem.
Juniper berry oil to the skin: Human skin is the highly structured security mechanism that guards us from the harmful effects of virus, bacteria, fungi and many other harmful micro-organisms. Treating it with ordinary alkaline soaps might spoil the protective layer of the skin formed by sebum (oily and acidic mantel produced by the sebaceous glands).
Ayurveda prescribes Abhyanga or the art of Ayurvedic massaging with the use of essential oils aiding in toning the muscles, relieving muscular tension, protecting the skin and for creating a natural barrier that can protect the skin from the outside forces.
Juniper berry oil has excellent moisturizing properties that help in treating various skin problems like acne, dermatitis and eczema. Skin problems are often associated with the vitiation of vata dosha. Juniper berry oil has the power to pacify excess of vata dosha and helps in the treatment of dandruff and psoriasis.
Three drops of Juniper berry oil blended with 2 drops of Lavender oil, 2 drops of Grapefruit oil added to your mild skin care creams and lotions can help in controlling the excess secretion of sebum, responsible for pimples, blackheads and redness of the skin cells.
A 2003 study on "Antibacterial and Antifungal activity of Juniper berry oil and its selected components" published in Phytotherapy research concludes that Juniper berry oil possesses antibacterial and antifungal activity.
A 2010 study published in "Pharmacognosy Research" by the Shiraz University of Medical Sciences in Iran, has confirmed that juniper berries' essential oil contains excellent antioxidant effects and the capacity to combat destructive free radicals.
Juniper berry oil also has circulatory and tonic properties that nourish the skin cells from within. Massaging the affected parts with 2 drops of Juniper berry oil, 2 drops of Rosemary oil and 2 drops of Geranium oil along with 3 ml of Sweet Almond oil can assist in the treatment of scaly, itchy scalp in dandruff, psoriasis, eczema and inflammatory skin conditions.
You can compliment this massaging with a warm compress for letting the remedial properties of the essential oils to penetrate the skin deeply.
Juniper berry oil to the joints, kidneys, digestive system and liver: Stagnation of water deposits, uric acid, salt and toxic remains in the system lead to chronic health conditions like rheumatism, arthritis, edema, swollen joints, dropsy, cystitis, renal calculi or kidney stones and urinary infections.
People with kapha imbalance can benefit highly from Swedhana (Panchakarma treatment for elimination of toxic remains through sweat). Massaging the affected region, especially the knees and joints in case of arthritis and rheumatism with 5 drops of Juniper berry oil, 4 drops of Cinnamon oil, 5 drops of Rose Geranium oil, 5 drops of Eucalyptus oil and 5 drops of Orange oil with 4 ounces of Sesame oil can help in promoting blood circulation in the painful area, reduces pain by causing numbness.
You can reduce inflammation, swelling, redness and soreness of the muscles by using a hot compress. This aids in discarding the toxic remains in the system through sweat and urine by enhancing its quantity and frequency.
Light Miller, in her book "Ayurvedic Remedies: For The Whole Family" has mentioned Juniper berry in numerous healing blends. The most significant among them are listed below for your reference.
Obesity or Weight loss blend: Massaging with 10 drops of Juniper berries oil, 10 drops of Grapefruit oil, 10 drops of Orange oil, 5 drops of Birch oil, 5 drops of Black pepper oil, 5 drops of Ginger oil with 4 ounces of Almond oil can assist in treating obesity by eliminating the excess fluids, toxic remains and fat deposits in the system by promoting frequent urination and sweating.
Gout: Gently massaging your abdomen with 5 drops of Juniper berry oil, 5 drops of Thyme oil, 5 drops of Cypress oil, 5 drops of Lemon oil, 5 drops of Basil oil, 5 drops of Myrtle oil along with 4 ounces of Coconut oil can help significantly in the treatment of renal calculi, cystitis, and gout.
Varicose veins: Varicose vein is a vata disorder caused due to lack of blood circulation, prolonged standing and sedentary lifestyle. Massaging with 5 drops of Juniper berry oil, 5 drops of Cypress oil, 5 drops of Lemon Grass oil and 2 ounce of Olive oil can help in stimulating blood circulation, relaxing the nerves, soothing the tensed muscles and alleviating pain associated with varicose vein condition, lumbago and sciatica.
Supports the digestive functions: Juniper berry oil has pitta or digestive fire enhancing attributes with its carminative, stomachic and warming properties. 5 drops of Juniper berry oil along with 2 drops of Ginger oil and 1 drop of Fennel oil to warm bathing water can assist in stimulating the secretion of bile, hydrochloric acid and digestive acids for treating sluggish digestion, relieving intestinal gas and colic pain.
Emotional benefits: Emotions play a vital role in all our lives, without which thoughts are of, nil value. These emotions are often the sound of the soul. The therapeutic and soothing aroma of Ayurvedic essential oils fortifies your energy centers and protects one from being deviated from your life's purpose.
Juniper berry essential oil has warm, appeasing, woody, earthy, engaging, sweet and energizing fragrance that pacifies the mind and sows the seeds of optimism in the limbic system of the brain. It is the brain's center of control and is in charge of transmitting commands to the entire body on thoughts, emotions and behavioral patterns.
Mental mayhems are often an output of stressful conditions. Stress can at times work quicker than cyanide in killing the potential of the mind and the brain. It occurs when the mind is occupied or forced with loads of chores than its bearing capacity. As a result, one's true efficiency and the normal functioning of the brain get disrupted.
Rage, resentment, fear, fatigue, anxiety, tension, lack of concentration and memory loss are few branches of the stress tree.
Inhaling the magical aroma of Juniper berry essential oil by adding 3 drops of Juniper berry oil with 2 drops of Neroli oil to your air freshener or diffuser, especially during the feeling of loneliness or before going to bed or during meditation, can help in bringing back the energy of self-confidence by augmenting your self-esteem.
This blend can also heighten the quality of your thoughts by boosting your creative quotient. 5 drops of Juniper berry oil and 2 drops of Bergamot oil added to your warm bathing water before your bedtime can relax your nervous system, soothe your muscles and induce peaceful sleep at night. Then, what else would stop you from starting a fresh and prolific day?!
Juniper berry oil has a pleasant and elevating aroma that instills a feeling of absolute peace and tranquility. Inhaling the sacred aroma of this oil helps in discharging the negative feelings, loneliness, suppressive thoughts and assist in developing intense inner consciousness.
2 drops of Juniper berry oil with 1 drop of Sandalwood oil, 1 drop of Vetiver oil and 1drop of Patchouli oil added to your vaporizer, diffuser, aromatic candles or room freshener during meditation and prayers can be a great soulful remedy.
It can help one to quit addiction, vent out negative feelings, disregard the pain of being abused, alleviate the trepidation of being neglected, deepen your level of thinking, build your bonding with the divine power and augment the connectivity of your soul with the universe.
Disclaimer: This article is meant only for educational purposes and is not recommended to treat or prevent any health condition or to replace any prescription medicines or the medical advice of your healthcare practitioner. We are not healthcare professionals and this information is shared only with the genuine thought of spreading the fragrance of Ayurvedic healing, world's oldest and the pioneer of all medical sciences on earth.
Use essential oils only for topical application in a diluted form, as organic and pure essential oils are highly concentrated substances and may cause allergic reactions, if used directly on the skin. Never ingest essential oils. Keep out of reach of children.
Juniper berry oil is not recommended for use during pregnancy as it has the potent to induce menstruation. Care should be taken in using this oil under the supervision of a healthcare expert, if you have inflammatory kidney disorders.
This entry was posted in Essential Oils - Learn About and Purchase and tagged Ayurvedic oils for anxiety disorders, Ayurvedic oils for concentration, Ayurvedic oils for edema, Ayurvedic oils for fatigue, Ayurvedic oils for gout, Ayurvedic oils for inner consciousness, Ayurvedic oils for obesity, Ayurvedic oils for renal calculi, Ayurvedic oils for rheumatism, Ayurvedic oils for spiritual enlightenment, Ayurvedic oils for stress, Ayurvedic oils for urinary infections, Ayurvedic oils for varicose veins, Ayurvedic oils for weight loss, Ayurvedic remedies for arthritis, Ayurvedic remedies for digestive problems, Ayurvedic uses of Juniper berry oil, Divine Ayurvedic oils, Health benefits of Juniper berry oil, Juniper berry essential oil and uses, Juniper oil in Ayurveda, Juniperus communis by AyurvedicOils. Bookmark the permalink.


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Auckland's new Fish Market is where you'll want to be all summer long
Words Madeline Saxton-Beer | 17 Dec 2018
At the heart of every great city, there is a fish market. Or at least, there should be. Which is why it should come as no surprise that Auckland, a global destination in the throes of doing some serious growing up, has just seen one emerge in the waterside precinct of Wynyard Quarter. Spearheaded by Sanford — New Zealand's oldest and largest fishing company — whose primary vision is to feed premium local seafood to local residents, the new Fish Market, open today, will enshrine ethical awareness and celebrate the intrinsic relationship New Zealanders have with their kai moana.
At the centre of the vast space, brought to life by Izzard Design and situated alongside Sanford's headquarters at the corner of Jellicoe and Daldy Streets, is the principle fishmonger, whose daily catch arrives on the nearby Halsey Wharf. It is here that the crux of the concept comes to life with piscine experts on hand to enlighten shoppers about various species, preparation, and methods of cooking. One of Sanford's main goals is to encourage visitors to try fish other than the main five (snapper, tarakihi, salmon, gurnard and hoki) and in doing so, promote the sustainable consumption of seafood.
Furthermore, an array of food vendors — some of them seafood-driven and others not — have culminated in the creation of a fully fledged food market offering, whereby visitors are able to purchase from the stall of their choice and enjoy a delicious feast in the common seating areas which have space for up to 400 diners. From the poke bowls of Hawaiian- and Pacific-inspired Ika Bowl and an offering from beloved Peruvian- Japanese restaurant Azabu, through to the wood-fired 'Super Pizzas' and a tasty Thai joint from Ex-Tok Tok chef Cameron Knox, the newly forged Fish Market is bound to have something for everyone.
Here's what to expect from the multitude of food purveyors on site:
Sanford & Sons
There's something for everyone at the market's central fishmonger, with a daily bounty of the freshest catch available to take home or eat tout de suite.
Sanford & Sons. Fishmonger
Azabu Light
The beloved Ponsonby restaurant will be delivering a taste of its famous Peruvian- Japanese fare including their famed tostadas and more.
Mar & Tierra
Offering a taste of Argentina and beyond, this South American grill will play host to a flame-grilled feast from 'sea and land'.
Billypot
Serving the classic pairing of mussels and fries, you'll be able to fill your boots at this promising new address.
Moules-fried from Billypot
Market Galley
With acclaimed chef Cobus Klopper (formerly of Ostro) at the helm, this eatery will herald sophisticated seafood dishes.
Super Pizza
Here you'll be able to source crowd-pleasing wood-fired pizzas where the range of toppings will cover every type of palate.
Serving as the fish market's resident watering hole, The Wreck is where palates will be wetted with beer, cocktails and non-alcoholic tonics.
Left: wood-fired pizza from Super Pizza
If you're venturing down for an early morning auction, you'll want to pick up a cup of Joe and a sweet treat from Karma Coffee first. Not to mention, the tempting freezer of Little Lato's premium quality gelato.
Tiki Thai
Ex-Tok Tok chef Cameron Knox will take the market's freshest ingredients and mix them into his Southeast Asian dishes.
Ika Bowl
The poke experts will be dicing up fresh fish and serving it in their Hawaiian- and Pacific-inspired rice bowls.
www.afm.co.nz
Wynyard Quarter
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redpajama_set_name: RedPajamaCommonCrawl


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Q: JMeter BackendListenerClient sends SampleResults too slow We wrote a custom BackendListenerClient which extends AbstractBackendListenerClient.  It sends data to our backend api, but we should wait 20-30s to get the first set of samples. Is there any way to improve performance?
Here is log:
1 2019-01-15 11:32:49,117 INFO o.a.j.u.JMeterUtils: Setting Locale to en_EN
...
92 2019-01-15 11:32:57,513 INFO c.c.p.MyBackendListener: start sending metrics(Empty)
...
2019-01-15 11:33:15,534 INFO c.c.p.MyBackendListener: start sending metrics(100 samples)

Any ideas?

Thanks

A: If you "wrote" it - my expectation is that you should know how to amend the interval.
For JMeter built-in listeners it's configurable via the following properties:

*

*backend_graphite.send_interval - for the GraphiteBackendListenerClient

*backend_influxdb.send_interval - for the InfluxdbBackendListenerClient
So if you copied and pasted existing JMeter code - it might be the case the listener you "wrote" respects this or that property. The properties can be defined either via user.properties file or passed via -J command-line argument

redpajama_set_name: RedPajamaStackExchange


Per-butanoylated efficacy, the expectation was that Bu4ManNAc had a need to show clearly excellent leads to cell culture exams in comparison to Bu5Man (that was just moderately effective of HDACi responses and glycosylation results derived from one regulatory mechanism alone, didn't adequately explain the impact of Bu4ManNAc in gene expression. area in its promoter area27,28 and conversely, MUC1 can modulate constitutive NF-B signaling within cancer tumor SB-715992 cells.27 This crosstalk led us to take a position that the hyperlink between reduced invasion (Body 3, Panels B and C) as well as the transcription of MUC1 (Body 5, Panel D) in cells incubated with Bu4ManNAc plausibly involved NF-B. NF-B activity in cells subjected to Bu4ManNAc or Bu5Guy was examined in two methods. Initial, a reporter gene assay was utilized to measure transcriptional activity powered by an NF-B consensus series upstream from the luciferase gene. Within this assay, a luciferase reporter plasmid was co-transfected with another plasmid encoding -galactosidase powered by an SV promoter and comparative distinctions in luciferase to -galactosidase signaled adjustments in NF-B transcriptional activity. TIE1 The MDA-MB-231 collection utilized throughout this research proved hard to transfect by regular lipofectamine protocols; as a result, these assays had been 1st performed in the human being HEK Advertisement293 collection where transfection efficiencies of 90% could possibly be obtained regularly. In these cells, the NF-B activator TPA and inhibitor EPO experienced the expected results (see Number S1 in the Assisting Information) therefore validating the assay inside our hands; it really is noteworthy a relatively higher level of NF-B transcriptional activity was within unstimulated cells, most likely reflecting high basal degrees of NF-B activity from the cancerous phenotype.27 In subsequent analog screening, Bu4ManNAc decreased NF-B transcriptional activity inside a dose-dependent way, while Bu5Man had negligible impact (Number 10, -panel A). Open up in another window Number 10 Evaluation of NF-B in HEK Advertisement293 and MDA-MB-231 cells treated with Bu4ManNAc, Bu5Guy, and settings(A) HEK Advertisement293 cells which were transfected with reporter gene plasmids and incubated with either Bu4ManNAc or Bu5Guy; Bu5Guy had no influence on NF-B activity in the reporter gene assay while Bu4ManNAc offered substantial inhibition with this cell collection. (B) Similar outcomes were noticed for Bu4ManNAc and Bu5Guy in the reporter gene assay in electroporated MDA-MB-231 cells. Mistake pubs for the transcription element reporter assays in Sections A and B symbolize SEM for self-employed experiments carried out in triplicate. (C) Incubation with either analog for 3 SB-715992 times didn't alter proteasome activity in MDA-MB-231 cells, whereas a 6 h treatment with epoxomicin created powerful inhibition; SEM was 4% for those data factors (and error pubs were not consist of because these were generally smaller sized compared to the data icons). (D) Endogenous NFKB1 (p105) mRNA amounts were decreased by Bu4ManNAc however, not by Bu5Guy in MDA-MB-231 cells; mistake calculated predicated on the coefficient of variance (CV) for routine quantity of quadruplicate replicates was 2% (not really demonstrated). Having discovered that NF-B activity in analog-treated HEK cells shown the effect of Bu4ManNAc and Bu5Guy on invasion in MDA-MB-231 SB-715992 cells (i.e., Bu4ManNAc was inhibitory and Bu5Man hade no impact), we following examined NF-B activity in the breasts cancer collection through the use of electroporation (that was far better than lipid-based transfection in MDA-MB-231 cells). The reporter assay demonstrated similar outcomes in the MDA-MB-231 cells (Number 10, -panel B) as acquired in the HEK cells (Number 10, -panel A) other than Bu5Man demonstrated a development towards being somewhat activating (rather than having an negligible effect on activity). In both lines, nevertheless, it had SB-715992 been unambiguous that Bu4ManNAc significantly inhibited NF-B within a dose-dependent way, producing a 75% decrease at 125 M. It really is worthy of noting that because NF-B activity was normalized to an interior control (a co-transfected plasmid using the -galactosidase gene powered by an SV promoter), the noticed reduction in pathway activity had not been an artifact of nonspecific suppression of transcription or translation because of nonspecific cytotoxicity. Bu4ManNAc Inhibits the Endogeneous NF-B Pathway Having showed that Bu4ManNAc inhibited NF-B activity in reporter gene assays, we following verified that substance had an identical effect on the endogenous NF-B pathway. Reduced amount of proteasome SB-715992 activity, a common but in no way ubiquitous quality of little molecule NF-b inhibitors, was examined being a potential system root the suppressive ramifications of Bu4ManNAc on NF-B. The proteasome inhibitor epoxomicin (EPO), which blocks degradation of ubiquinated IB by sequestering NF-B in the cytoplasm, was utilized being a positive control within this assay; unlike this substance, nevertheless,.
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A Darling Kind of Life: It's My Birthday!
There's something on my heart that I want to share with you-but mostly putting it on here so I'll have it written out.
When I posted that quote I didn't have a specific idea of what that may be that He's asking of me this year- but whatever its going to be, I want my answer to be yes.
We have been going through a period that has been super challenging with Cale. It's every day and I fully rejoice we have Jesus. We claim victory and we know we'll make it to the other side but this middle part right now is haaaaaard.
To make this story short, Mama made a yummy dinner, one she makes every New Years day. I didn't help at all, I played with the kiddos :) Nora helped me set the table extra special though.
Cale ended up having a moment. I won't give details but it ended with frustration and tears for me.
We ate dinner while he stayed upstairs and then one of our friends came to pick him up and get him out of the house for a little bit- I am so grateful.
After dinner I cleaned up the kitchen and while washing there were a lot more tears. Outside of these moments, I know it's brain injury. I am able to reason with myself but it definitely feels like I'm fighting a battle up stream and I just struggle sometimes to know what the next step needs to be-and many days we just take one step at a time.
This sign was a little bit of a splurge and now I know it was money well spent. As I read it I quickly started to add, "my answer is yes."
I will be a woman who is humble and gentle.
I will make allowance for others faults.
Sometimes, God does have callings into a ministry, or getting married or a move or whatever else- but sometimes we just need to say yes to loving him and loving people more. Maybe as we walk through our days, we need to remember to make allowance for others faults because we all mess up.
We will continue to have hard days. We know that and it would be so whether we lived with brain injury or not. It's just going to be that way in a sinful world.
I am SOOO glad you posted. I check every day and am blessed when you write. Thank you.
What a WONDERFUL verse. I'm going to find a way to mount it on my wall. I NEED to remember it. Father has been working on gentleness with me, loving in spite of faults and EVERYTHING that verse holds. I, too, want to be a "yes" daughter. Sometimes, I have to back that up a bit though, and say I want to want to. '~' Father has us on different paths, yet we both fill Father's bottles with our tears. He says He keeps them, you know. It'll be way cool to see what He's done with them when we get to New Earth.
YES! It is one that needs to be up in our view to see daily!
Thank you so much for posting. Sometimes it is so hard to be understanding of others and their reasoning, no doubt especially so with 2 youngsters! I'm amazed at how you make it all work on top of your dedication and support for your husband. I suppose sometimes it's tough as you understand why Cale is struggling but also feel overwhelmed with all the pressures in your life. No doubt though your children will grow up to be strong, courageous, empathetic warriors in Gods name. The challenges we endure move us closer to God!
It WAS your Birthday, and I blew it and missed it! Urgh! Sorry.... but I wanted to take this moment to send belated wishes, to pray for you, to send our love, and to acknowledge that we all have struggles and your words and plaque is perfect! May we all remember, and be blessed by them, and be willing to say yes!


Often when I am meeting with a church's leadership for the first time to discuss a fund-raising campaign I am asked the following questions, "Our congregation has not been able to meet the budget for several years now. If we could get our members to give more, we could meet our budget. How can we get them to give more?" or "We really need our members to give much more generously if we are to raise the funds that are necessary to renovate our facilities. How can we persuade them to give more?" I am always alerted when I hear the word "them" because it means that the church leaders don't see themselves as part of the problem. The questions are usually asked with a tone that suggests that if those other members would do their part the congregation could reach its fund-raising goal.
In reality a congregation or non-profit organization will not dramatically increase its giving unless its leadership is willing to lead by example, by increasing its own giving. If those who are in leadership do not give generously in proportion to their blessings, there is no example of sacrificial giving, and the general membership will reflect the level of commitment of the leaders. We really can't ask others to do something that we are not willing to do ourselves. But often Church or Board leaders seem to mentally set themselves apart from the rest of the congregation or organization, and feel that it's the "others" who are not doing their part. "If we could get them to take their responsibility and to do their part, we could reach our goal." This kind of thinking reflects an attitude that giving is a duty, and if the members would give dutifully their organization would reach its goal.
But the fact is that "dutiful giving" is seldom "cheerful giving" and consequently it is not generous giving. In these times we have many options about where to spend our money or to give our money. The church no longer has the corner on the market for members to feel obliged to give dutifully. In these times, members generally do not respond because they are told to give, or are pressured to give more. If individuals give because they want to, rather than because they are pressured to give, they always give more, and often they will give wholeheartedly, joyfully, and generously, sometimes much more than they have ever given before.
So how do you get members to give more wholeheartedly, if you don't want to try to persuade them or pressure them to give dutifully? A faith-raising perspective generates a straightforward answer. If we want to get our congregations or non-profit organizations to give up to their potential, we must inspire the members to be more generous. Remember that the word in-spire means to be filled with the spirit. It means that we are inspired by what God is doing through us, rather than taking credit for what we are doing. When leaders lead by example and exhibit joy in generosity, it is inspiring and it can be contagious. Others will pick up our spirit and will be inspired to give more generously.
How do leaders overcome their own fears about dramatically increasing their own giving, so that they can lead by example? The first step is to put our faith in God's abundant providing in front of our fear, and step out with courage. Change how we think about and relate to giving. Start out by deciding to give first, as a pacesetter. In other words think in terms of "first fruits," and make a commitment to decide how much you are going to give. Then budget accordingly. Many people give from what they have left over after all the things they spend on, which is often token giving. When we buy a new car or home, we find ways to make those monthly payments. Giving works the same way. When we change our habits, by giving first as a your top priority, we discover that God provides abundantly of everything we really need.
The second thing we can do if we want to overcome fears about giving is to surround ourselves with generous people. If our friends and associates are not generous it will be hard for us to maintain a generous spirit. Find ways to interact with those who are most generous in your church or community. Ask them how they think about giving, how they have the faith to step out with courage, and how they manage to give both sacrificially and generously. They often will tell us that generosity provides great benefits to the giver, and that it is a privilege to give, to be able to make a significant difference in the world.
Lastly, make it a habit to give generously every month. The more regularly we give, the more comfortable we are with generosity, the more we will find that giving does indeed bless the giver. We experience the joy and satisfaction that comes when we are regularly making a lasting, important improvement in the lives of others.
When church leaders or organizational leaders are inspired to give more generously than ever before, because they see that their giving can make an important difference in the world and help more people, they are inspired to give more and they often express that inspiration with enthusiasm, and that enthusiasm can be contagious. So rather than trying to push or persuade or pressure members to give more, focus on inspiring them to give more by leading by example. Before focusing on what others ought to do, think first about how much more we can give if we truly give in proportion to our gifts.


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Landmark global strategy on oral health adopted at World Health … – World Health Organization
Member States agreed to adopt a global strategy on oral health, which will inform the development of a new global action plan, including a framework for tracking progress with targets to be achieved by 2030.
Oral diseases are among the most common noncommunicable diseases (NCDs) worldwide. While largely preventable, there were estimated to be more than 3.5 billion cases of oral diseases and other oral conditions globally in 2019. Oral health varies over the life course from early life to old age, is integral to general health and supports individuals in participating in society and achieving their potential.
The global strategy sets the bold vision of universal health coverage (UHC) for oral health, reaching all individuals and communities by 2030. This enables people to enjoy the highest attainable state of oral health and live healthy and productive lives, including by tackling social and commercial determinants and risk factors of oral diseases and conditions.
The global strategy is the first concrete step towards the full implementation of last year's WHA74.5 resolution on oral health. With actions for WHO Member States, international partners, civil society and the private sector, the strategy sets four overarching goals to guide Member States, to:
These goals will require following a set of guiding principles: taking a public health approach; integrating oral health with primary health care; and adopting innovative workforce models to respond to population needs. Placing people at the heart of oral health services is critical, including through tailored interventions across the lifecourse, and optimizing digital technologies.
In addition, the strategy includes six strategic objectives, on oral health governance, oral health promotion and oral disease prevention the health workforce, oral health care, oral health information systems, and oral health research agendas.
Milestones for the WHO Secretariat are also established. By 2023, WHO will translate the strategy into an action plan for public oral health. This will include a monitoring framework for tracking progress, with measurable targets to be achieved by 2030. By 2024, WHO will recommend cost-effective, evidence-based oral health interventions as part of the updated Appendix 3 (also known as the 'best buys') to the NCD Global Action Plan for the Prevention and Control of NCDs, and the WHO UHC Compendium.
WHO will also continue to update technical guidance to ensure safe and uninterrupted dental care. This includes scaling and sustaining innovative practices using digital technologies and supporting Member States' effort to include Noma in a planned WHO review process to consider the classification of additional diseases within the road map for neglected tropical diseases 2021-30.
Work will also focus on strengthening oral health information systems. This includes creating a new oral health data platform, developing standardized data-gathering technologies and methods, and creating oral health indicators for population health surveys. Together, these action will monitor the progress of implementation of work on oral health, while also providing timely and relevant feedback to decision-makers at the national level.
"Oral health is a fundamental right. It is very concerning that despite burdening billions of people around the world, many oral diseases which could be prevented or treated with simple, evidence-based and cost-effective interventions. People continue to experience pain and suffering, alongside severe financial pressures on families and communities.
The impact of poor oral health around the world is enormous and action is urgently needed to benefit all, young and old, across the lifecourse" said Dr Bente Mikkelsen, Director for Noncommunicable Diseases, World Health Organization.
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Each year the Honeynet Project's annual workshop brings together top information security experts from around the globe to present their latest research efforts and discuss insights and strategies to combat new threats. The workshop provides participants and sponsors with significant exposure to world-class professionals and a diverse range of information security topics. We invite you to be part of our workshop in 2017 through various sponsorship opportunities.
Who will attend the workshop?
Top information security experts from around the world will gather in Canberra to present their latest research efforts and discuss insights and strategies to combat new threats. With the growing interest in developing Australia's cyber security capacity, the Workshop will be very attractive for Australians to attend and be shown the latest developments.
What are the benefits of the sponsorship or exhibition?
The project workshop provides participants and sponsors with significant exposure to world-class professionals and a diverse range of information security topics. This is the first time the workshop is coming to Australia, with previous workshops being held in San Antonio (2016), Stavanger (2015), Warsaw (2014), Dubai (2013), San Francisco (2012), Paris (2011) (First public event), Mexico City (2010) and Kuala Lumpur (2009). This is a unique opportunity to reach an audience that is not often available to Australian companies. The workshop is expected to attract 40 Honeynet Project members and 200 participants from all over the world.
This is the summary of the available sponsorship opportunities. Full details are described in the sponsorship document.


text:
Prudhomme back on Tour de France after week of COVID-19 isolation
By Cyclingnews
French Prime Minister who drove in lead car with race director also back to work
Tour de France director Christian Prudhomme on stage 4 (Image credit: Bettini Photo)
Tour de France director Christian Prudhomme returned to the race on Monday one week after testing positive for COVID-19 and having to self-isolate. According to Reuters and Le Parisien, Prudhomme was asymptomatic for the virus which has swept across the globe causing almost a million deaths and has subsequently tested negative, according to Lesoir.
Prudhomme left the race on the first rest day in La Rochelle after testing positive for the coronavirus. His lead car driver Gilles Maignan, considered to be in close contact with Prudhomme, was also forced to isolate, as did the French Prime Minister Jean Castex, who rode in the car with both men on the day before the positive test.
At the time, Castex praised the Tour for its security measures to protect against spreading the virus after celebrating the victory of Frenchman Nans Peters (AG2R La Mondiale) after stage 8.
On that stage, large crowds assembled on the Col de Peyresourde, most masked, but since then the race has banned spectators at the stage finishes making for a strangely quiet finale on the Grand Colombier on Sunday.
Tour de France director Christian Prudhomme positive for coronavirus
Ineos Grenadiers, Mitchelton, Cofidis and AG2R staff test positive for coronavirus at Tour de France
Tour de France COVID-19 counter to be reset for second rest day tests
Fans banned from Tour de France starts and finishes in coronavirus red zones
After being informed he was considered a close contact of a confirmed COVID-19 case (Prudhomme), Castex underwent a test that came back negative, but remained isolated for the week.
Castex announced on Friday that the country would no longer force positive individuals to isolate for 14 days, cutting the required quarantine period in half to seven days for asymptomatic individuals, reasoning that most people were not isolating for two weeks and that the shorter period might be met with a higher compliance level.
"We are most contagious in the first five days either after the first symptoms or after testing positive. After that, the level of contagiousness decreases significantly," French Health Minister Olivier Véran told France Inter.
Antoine Flahault, professor of public health and director of the Institute of Global Health at the University of Geneva, said on Twitter that less than 10 per cent of asymptomatic individuals are still contagious after five days.
Castex announced the new requirements even as the number of cases has spiked in France, in particular around Marseille, Bordeaux and greater Paris, bringing the average cases to 72 per 100,000. The percentage of positive tests has also gone up but the French government is still working to counteract the economic damage caused by widespread stay-at-home orders in the spring and wants to avoid another period of prolonged confinement.
Prudhomme and Maignan returned on Monday just as the Tour de France team bubble underwent its third round of COVID-19 testing, the results of which will be expected on Tuesday. Race leader Primoz Roglic assured that his team had tested negative even as the Jumbo-Visma team clarified they had not yet received their results.
Any rider testing positive will have an immediate second test to rule out a false positive, while any team with two confirmed positives will be required to exit the race.
So like that, Prudhomme will take over from temporary replacement François Lemarchand and be back waving the flag from the sunroof of the red lead vehicle when the Tour de France resumes with stage 16 at La Tour-du-Pin (Isère).
Cyclingnews is the world's leader in English-language coverage of professional cycling. Started in 1995 by University of Newcastle professor Bill Mitchell, the site was one of the first to provide breaking news and results over the internet in English. The site was purchased by Knapp Communications in 1999, and owner Gerard Knapp built it into the definitive voice of pro cycling. Since then, major publishing house Future PLC has owned the site and expanded it to include top features, news, results, photos and tech reporting. The site continues to be the most comprehensive and authoritative English voice in professional cycling.


text:
Daily almanac
Today is Saturday, May 23, the 143rd day of 2009. There are 222 days left in the year.
HIGHLIGHTS IN HISTORY
� On May 23, 1934, bank robbers Clyde Barrow and Bonnie Parker were shot to death in a police ambush in Louisiana.
� In 1430, Joan of Arc was captured by the Burgundians, who sold her to the English.
� In 1533, the marriage of King Henry VIII to Catherine of Aragon was declared null and void.
� In 1701, William Kidd was hanged in London after he was convicted of piracy and murder.
� In 1939, the submarine USS Squalus sank during a test dive off the New England coast. Thirty-two crewmen and one civilian were rescued, but 26 others died.
� In 1944, Allied forces bogged down in Anzio, Italy, began a major breakout offensive.
� In 1949, the Federal Republic of Germany (West Germany) was established.
� In 1984, Surgeon General C. Everett Koop issued a report saying there was "very solid" evidence linking cigarette smoke to lung disease in nonsmokers.
� Ten years ago: Pro wrestler Owen Hart, "The Blue Blazer," died when he fell 78 feet as he was being lowered into the ring at a World Wrestling Federation show in Kansas City, Mo.
� Five years ago: A large section of roof of a new passenger terminal at Paris' Charles de Gaulle airport collapsed, killing four.
� One year ago: Hillary Rodham Clinton apologized after citing the 1968 assassination of Robert F. Kennedy as a reason to remain in the race for the Democratic presidential nomination.
"He who cannot rest, cannot work; he who cannot let go, cannot hold on; he who cannot find footing, cannot go forward." -- Henry Emerson Fosdick, American clergyman (1878-1969)


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, também escrito como 2001 QH298, é um objeto transnetuniano (TNO) que está localizado no cinturão de Kuiper, uma região do Sistema Solar. Este corpo celeste é classificado como um plutino, pois, o mesmo está em uma ressonância orbital de 2:3 com o planeta Netuno. O mesmo possui uma magnitude absoluta de 7,7 e tem um diâmetro com cerca de 127 km.

Descoberta
 foi descoberto no dia 19 de agosto de 2001 pelo astrônomo Marc W. Buie.

Órbita
A órbita de  tem uma excentricidade de 0,107 e possui um semieixo maior de 39,250 UA. O seu periélio leva o mesmo a uma distância de 35,067 UA em relação ao Sol e seu afélio a 43,432 UA.

Plutinos
Objetos do cinturão de Kuiper
Objetos transnetunianos
Objetos astronômicos descobertos em 2001

redpajama_set_name: RedPajamaWikipedia


Is there a way to get the true values of FTOTINC INCTOT or HHINCOME from the census bureau?
We are working on an analysis of inequality from 1970 to 2010 and the above mentioned top coded variables are skewing our "top 1%" income earners variable. Is there a way to get true values or as close to them as possible (especially from the 1970 and 1980 censuses) so that our research reflects income inequality more realistically? Thanks!
You need to request access to the Census Research Data Center. UMN obviously has one – see http://www.census.gov/about/adrm/fsrdc/locations/minnesota.html.
Thank you! I was wondering if you mind expanding on the comment about the impossibility of calculating correct standard errors in Gini in survey data, I have used Stata's svylorenz command. Should I be careful with these standard errors? I know this is off-topic and unrelated to IPUMS but thought I would ask anyway.
A few years back, I did my own research into estimation of Gini indices and their standard errors with complex survey data. (I wrote -epctile- and -gconc- back then.) First off, there are probably five or so different definitions of Gini index for i.i.d. data, and they all have different generalizations for weighted data. So it gets difficult right there. Second, I found that none of the four or so variance estimation methods I was comparing was totally bullet-proof. It is technically a difficult exercise: different twists of the complex sampling designs affect the different variance estimation methods differently. The paper has never been published.
Other than that, Stephen Jenkins is definitely one of the top methodologists as far as income inequality is concerned. In -svylorenz-, he implements *a* method for weighted Gini, and *a* method for standard errors that are both defensible.
Thank you for your response! It would be a great contribution to the community if your paper gets published, I hope it does! I can imagine how complex estimating variance for complex survey design data can be. I'm stuck trying to model heteroskedasticity in a GLM using ML to correct for inefficiency and have acceptable variance estimates. Thanks again for your help! I will talk with my advisor to see if it is worth sending a proposal for the non-public census data.


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Two more countries have taken a bold stand against genetically-modified organisms (GMOs), according to new reports. The South American nation of Venezuela is currently in the process of crafting legislation to bar transgenic seeds and crops from entering the country, while biotechnology giant Monsanto has completely withdrawn all of its business efforts from the European nation of Denmark, where food companies and the genera public have wholly rejected GMOs.
As reported by Venezuela's Prensa Latina, the nation's leaders recognize the dangers inherent in adopting transgenic agricultural technologies, particularly with regards to plant diversity and food sovereignty. In order to sustain its rich agricultural heritage, in other words, Venezuela knows that it must place strict limits on its seed market, and support the efforts of small farmers who are the bread and butter of its clean food supply.
"The new legislation would protect small and medium producers, favor the use of seeds for the environment and human health, and the creation of an institution working on the topic," explained Venezuela's Socialist Deputy Alfredo Urena about the changes. He went on to add that laws regulating against transgenic seeds and technological packages are needed to protect both the food supply and human.
In similar news, Denmark has all but completely phased out GMOs as well. Though not technically illegal there, GMOs have never really been accepted by either the public or food companies in Denmark. Even Monsanto, which is known for using sleight of hand to force public acceptance of GMOs in countries like the U.S., has been unsuccessful in maintaining any sort of business presence in the European country.
"It is not really very surprising when you consider that chemistry company BASF stopped their biotech experiments in Europe in 2012 and that agro company Syngenta moved their studies several years earlier," says Klaus Sall, a GMO industry expert, in reference to Monsanto's quiet decision to withdraw from Denmark. "This will have an impact on the international dissemination of genetically modified crops on a global scale."


Tonight, we resume our look at the genome, the science of D-N-A, the genetic code for life as we know it. We'll look at recent advances — and setbacks — for the once promising field of genetic-based personal medicine, including the FDA's decision to shut down medical predictions by 23-and-me, a well-known consumer genetic company.
12 years of "No Crap On Tap"


"Simon Cordova at Speck Studios was the whole reason the video turned out so good. He heard the album before it came out and really gave it it's own world. We seemed to be striving for the same thing. So that made it really easy when we got to the storyboard stage."
173 queries in 2.339 seconds.


G&A Partners specializes in helping companies like yours grow their businesses and take better care of their employees by providing them with the people, processes and technology they need to streamline their administrative HR functions.
© 2017 G&A Partners. All rights reserved.


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Public relations director Erica leads her team in content creation, media relations, and influencer marketing efforts. When she isn't working, you can find her chasing after her two growing kiddos. Chat with her about all things PR or Orangetheory Fitness at ericat@2rm.com.


The goal of the attacker performing cryptanalysis will depend on the specific needs of the attacker in a given attack context. In most cases, if cryptanalysis is successful at all, an attacker will not be able to go past being able to deduce some information about the plaintext (goal 3). However, that may be sufficient for an attacker, depending on the context.
High level: Cryptanalysis generally requires a very significant level of understanding of mathematics and computation.
The target software utilizes some sort of cryptographic algorithm.
An underlying weaknesses exists either in the cryptographic algorithm used or in the way that it was applied to a particular chunk of plaintext.
The encryption algorithm is known to the attacker.
An attacker has access to the ciphertext.
Computing resource requirements will vary based on the complexity of a given cryptanalysis technique. Access to the encryption/decryption routines of the algorithm is also required.
An attacker discovers a weakness in the cryptographic algorithm or a weakness in how it was applied to a particular chunk of plaintext..
An attacker leverages the discovered weakness to decrypt, partially decrypt or infer some information about the contents of the encrypted message. All of that is done without knowing the secret key..
Use proven cryptographic algorithms with recommended key sizes.


Lead generation continues to be one of the most popular online marketing tools. It's easy to see why. When executed well, lead gen campaigns can provide high-quality prospects in real time and deliver substantial returns on investment. However, managing a lead generation opportunity efficiently and ensuring you're getting it right is pretty much impossible without a reputable high-end technology platform.
Some companies still think about lead generation in terms of the sheer volume of leads delivered. Having a large number of leads to work with can be a good thing. However, unless these prospects are delivered instantly and are highly relevant, then you're pretty much working with useless data and conversion rates will be low. More leads, therefore, don't always equal more conversions.
So how confident are you that your campaign is generating highly relevant prospects and delivering the best results? Let's look at some key areas you should consider to ensure your campaign's success.
We all know how important data security is. So, before you embark on a new campaign, choose a technology platform that easily passes the most stringent data security tests.
With lead generation, timing is of key importance. The speed at which data can be received, processed and distributed for conversion is crucial. The ideal, of course, is in no time! Real-time scoring, pricing, validating, transferring and analysing of leads and performance will vastly improve your campaign's results.
Ensure your provider can grow (or shrink) with you and enables you to deploy campaigns of any size with robust, reliable and scalable technology. Cloud-based platforms offer a versatile option, as they will let you easily add or remove capacity as required. Scale works both ways though, so use cap management features to make sure you are getting the right volume of results. Technology can also help you manage both suppliers and sources with fast and easy set-up, adaptation and removal of budget allocations and caps, creatives, channels and formats.
The level of insight is only as good as the output of your analytics tool. Without decent validation, data collection and campaign management, you're essentially working with incorrect data. Ensure solid reporting metrics are available 24/7. That way you can identify under or over performers and you will be alerted instantly when issues arise.
Your technology platform should digest the mountains of data into a usable format in real-time. Whether internal or third-party feeds, small or big data, advertiser or supplier perspectives, there are hundreds of ways to slice, dice, customise and pivot it. The data you are presented with should perfectly fit your needs and those of the different people logging in to view it.
Success means different things to different companies, so whatever it means to you, ensure the platform you choose can identify and optimise it. The easiest way is by creating customisable Key Performance Indicators (KPIs). Multiple KPIs for measuring early, mid and long-term performance will help you properly apportion campaign budgets and enable you to make the most of your media spend.
There really is a lot more to lead generation than sheer volume. Even so, it's pretty straightforward and with the right technology, campaigns can prove very lucrative.
So how can we help? Well, Lead Intelligence is the most technologically advanced lead management platform available. It streamlines all lead buying and management process for agencies and advertisers, providing insight and reliability.
Lead Intelligence helps you through every stage of your marketing campaign including planning, campaign set-up and management, validation and optimisation, budgeting and billing, fulfilment and conversion plus reporting and analysis.
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text:
Constantijn J. Hering (Oschatz, 1 de enero 1800 - Filadelfia, 23 de julio de 1880) fue un médico homeópata, botánico, alemán. Pionero de la homeopatía de EE. UU.

Biografía
Era originario de Oschatz, estudiando medicina en la Universidad de Leipzig donde comenzó su interés por la homeopatía. Había sido contratado para escribir un libro refutador de la homeopatía, pero tras la lectura de la obra de Samuel Hahnemann e investigando reclamos clínicos de la homeopatía, se convenció de su eficacia, buscó el autor, y se convirtió en su amigo personal. Comenzaron correspondencia en 1824. Más tarde, Hering fue tratado por una herida de disección con el remedio homeopático Arsenicum album (arsénico blanco o trióxido arsenical) y el dedo se salvó, provocando aún más su interés.

Fue por un tiempo instructor en matemática e historia natural en el Instituto Blochmann, Dresde. En 1826, tras graduarse por la Universidad de Wurzburgo, recibió una comisión del Rey de Sajonia para llegar a Surinam en una expedición de historia natural. Se instaló allí por un número de años y comenzó la práctica, antes de emigrar a Pensilvania en enero de 1833.

Fue uno de los pioneros de la homeopatía en EE. UU. y ayudó a difundir la homeopatía allí. Fundó una escuela homeopática, la primera de su tipo en cualquier país. De 1845 a 1869 cubrió las sillas de los institutos de medicina y materia médica en el Colegio de Homeopatía de Filadelfia. Dedicó mucho estudio a curas para las mordeduras de serpientes venenosas y de hidrofobia, y desarrolló muchas de las teorías de Hahnemann.

Introdujo una serie de remedios homeopáticos para la materia médica, como Lachesis, Psorinum, Glonoinum.

Familia
Su padre era el compositor germano Carl Gottlieb Hering. Su sobrino era el fisiólogo Ewald Hering.
Uno de sus hijos era Walter E. Hering, el fundador de Globe Ticket Co. la empresa de entradas más antigua de Estados Unidos. Otro de sus hijos fue Hermann S. Hering, que, por un momento, dio clases e investigó en la Universidad Johns Hopkins, y más tarde se convirtió en una figura prominente en la iglesia Ciencia cristiana, siendo allí médico, profesor y conferenciante. Sirvió un mandato de presidente de la iglesia y como primer lector nombrado en la Primera Iglesia de Cristo, Científica, en Boston, y más tarde en la Iglesia de Ciencia Cristiana en Concord, NH.

Algunas publicaciones
Fue autor de una serie de obras homeopáticos importantes, incluyendo los diez volúmenes de Guiding Symptoms, que no llegó a completar. Fue editor conjunto de la Medical Correspondent (Allentown, 1835-1836) de la Miscellanies of Homeopathy (Filadelfia, 1839), de North American Homœopathic Quarterly (New York, 1851-1852) y el Homœopathic News (1854), y fundó y editó American Journal of Homœopathic Materia Medica.

Publicó muchos libros en alemán y en inglés, incluyendo:
 Rise and Progress of Homoeopathy. Filadelfia, 1834, traducido a varios idiomas.
 The homoeopathist (1835-1838) (ed. germana] 217 p. University and State Library Düsseldorf)
 Organon of homœopathic medicine. Con Samuel Hahnemann. Ed. Academical Bookstore, 212 p. 1836
 Condensed Materia Medica (1837) reimpreso de B. Jain Publishers, 968 p. 2001 ISBN 817021288X, ISBN 9788170212881
 Effects of Snake Poison 1837 / Wirkungen des Schlangengiftes . Blumer, Allentaun [Pa.] 1837
 Guiding Symptoms and Analytical Therapeutics 1850, reimpreso como Herings Guiding Symptoms of Our Materia Medica] 5 v. de B. Jain Publishers, 4700 p. 2003 ISBN 8180563162, ISBN 9788180563164
 Domestic Physician 1851
 American Drug Provings (v. i. Leipsic, 1853)
 Materia Medica: With a Pathological Index... V. 1 de C. Herring's Materia Medica with a Pathological Index. Ed. Boericke & Tafel, 1873

Reconocimientos

Membresías
 Academia Nacional de Ciencias (Estados Unidos)

Referencias

Enlaces externos

Botánicos de Estados Unidos
Médicos de Alemania del siglo XIX
Homeópatas de Estados Unidos
Alumnado de la Universidad de Leipzig
Alumnado de la Universidad de Wurzburgo
Miembros de la Academia Nacional de Ciencias de Estados Unidos
Escritores en inglés del siglo XIX
Escritores en alemán del siglo XIX
Emigrantes alemanes hacia Estados Unidos
Fallecidos en Filadelfia


text:
Q: Conditionally color pandas column My dataframe looks like this:
Week    Item    Buyer   11  12  13
0   clothes buyerID1    2   3   4
1   food    buyerID2    2   1   1
2   water   buyerID     7   5   1

11, 12, 13 are the weeks. I am trying to conditionally color the rows of the last column to depict a change in items purchased week over week. I am using an adaptation of another answer here to do so, but I am running into an IndexingError: Too many indexers error.
Below is my modified code:
def highlight3(x):
#if increase
c1 = 'background-color: green'

#if decrease
c2 = 'background-color: red'

c3 = ''

#last row greater than value in second to last row
m1 = x.iloc[:, -1] > x.iloc[:, -2]

#last row lesser than value in second to last row
m2 = x.iloc[:, -1] < x.iloc[:, -2]

out = np.select([m1, m2], [c1, c2], default=c3)
return pd.DataFrame(out, index=x.index, columns=x.columns)

And then I apply it to my df using: df.apply(highlight3, axis=None)

A: Here's a solution:
data = """Week    Item    Buyer   11  12  13
0   clothes buyerID1    2   3   4
1   food    buyerID2    2   1   1
2   water   buyerID     7   5   1   """
df = pd.read_csv(StringIO(data), sep="\s+")

green = 'background-color: green'
red = 'background-color: red'

def style_last_week(x):
    s = pd.Series([""] * x.size)
    if x[-1] > x[-2]:
        s[x.size -1 ] = green

    if x[-2] > x[-1]:
        s[x.size -1 ] = red

    return s

df.style.apply(style_last_week, axis=1)

The result is:


Country Club Hills, in North Arlington, is grand with nice homes on big lots, but it's still a tight, warm neighborhood.
Who lives here: Young and middle-aged families, though some retirees are longtime locals.
The vibe: Kids take over cul-de-sacs for lacrosse and soccer. "It's still the kind of neighborhood where if someone gets sick, the neighbors take cookies and casseroles over," says Sharon Chamberlin, who has lived here for 47 years.
Homefront: This began as a small neighborhood of 1940s-style summer homes built into the Arlington hills and around the Washington Golf and Country Club. It's now a mix of some 500 ramblers, Tudors, and Colonials, which have retained a traditional look despite renovations.
When Rose DiNapoli, an interior designer who has lived in the neighborhood since 1994, and her husband bought their rambler, they added two floors from which they can see the National Cathedral.
For sale: Recent listings included seven homes ranging from just under $1 million to more than $2 million. A five-bedroom, Arts-and-Crafts-style house near Gulf Branch park was priced at $1.9 million. Older homes often become teardown fodder, but land can be worth $900,000 and more.
Meet you at the club: The 113-year-old Washington Golf and Country Club is the centerpiece of the social scene. Initiation costs $70,000, and you're likely to spend four years on the waiting list. On the Fourth of July, members and nonmembers spread blankets on the edge of the golf course to watch the club's fireworks.
Dog dip: Residents walk their dogs to the nature trails and native-plant garden around Gulf Branch Nature Center and down to the Potomac for a swim.
Biggest draw: Yorktown High, considered one of the best schools in Washington. Last year, the Siemens Foundation rated its Advanced Placement program tops in Virginia.
Drawback: Noise and inconvenience from constant home renovations. "People never leave; they add on," says real-estate agent Caroline Rocco.
Wine and Food: Country Club Hills is bookended by shopping centers. Lee Heights has several independently owned shops, including Pastries by Randolph and Arrowine, home to weekend winetastings. The second, farther west on Lee Highway, boasts a Starbucks, Baskin-Robbins, Harris Teeter, and a few small shops and restaurants, including Taqueria Poblano.
Why it beats AU Park: Lots are as big as an acre. "It's a neighborhood where there's room to breathe," DiNapoli says.
On the Web: Yorktown High School (yhspatriot.yorktown.arlington.k12.va.us); Jamestown Elementary (www.arlington.k12.va.us/schools/jamestown); Arrowine (arrowine.com).


A will cannot dispose of any of the decedent's property until it is admitted to probate.
Lost or destroyed will? In order for a will to be admitted to probate, it must be executed in accordance with the formalities required by Florida law. The testator must sign his will at the end in the presence of two attesting witnesses. The attesting witnesses must sign in the presence of each other and in the presence of the testator. If the testator attaches a self-proof of will, the will may be admitted to probate without further proof. Without a self-proof of will, an oath of one of the attesting witnesses may be required before the will is admitted to probate.
Upon the testator's death, if a will, executed by the testator and kept in their possession, cannot be found, there is a presumption, absent other evidence, that it was destroyed with the intention of revoking it. However, this presumption may be overcome and the will may be admitted to probate if an interested person is able to establish the full and precise terms of the lost or destroyed will. The content of the lost or destroyed will be proven with a correct copy of the will and the testimony of one disinterested witness. Without a correct copy, the content may be established through the testimony of two disinterested witnesses.


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We all love our pets. What better way to honor them than with a beautiful painting? In this three week workshop taught by Lukas Phelan, we will provide the materials and know-how to create a one of a kind acrylic painting of a pet that is special to you or a loved one. Learn the fundamentals of acrylic painting and pick up some new tricks. Please come prepared with printed images of the pet you would like to immortalize (or send them to lukas@zootownarts.org to be printed here). The ZACC is also a pet friendly location, so if you think your animal can play well with others and let you focus on your painting, feel free to bring them along.
This group will meet every Tuesday starting April 23rd going through May 7th.


Outlook: With the return of 13 of 18 runners and a strong group of newcomers and transfers, Haggins has his sight set on winning the county and district this year. Senior Shalaneya Bryant qualified for state in two events last year and Haggins believes she may be able to make a return trip. Ashley Linderman will have to lead a group of inexperienced distance runners. Coach Haggins said distance has been the team's primary downfall over the past few years, but the addition of soccer players to the team might give the Red Devils an additional edge.


text:
ALCS Game 4: Yankees Need Big Game From A.J. Burnett
By Ed Valentine@Valentine_Ed Oct 19, 2010, 4:48pm EDT
Share All sharing options for: ALCS Game 4: Yankees Need Big Game From A.J. Burnett
(Sports Network) - A.J. Burnett hopes to put a miserable regular season behind him this evening when he takes the ball in Game 4 of the American League Championship Series trying to draw the New York Yankees even in the best-of-seven set against the Texas Rangers at Yankee Stadium.
Burnett went into last year's playoffs as the team's No. 2 starter, but he has yet to pitch this postseason following an awful year that saw the righty go 10-15 with a 5.26 earned run average.
"I mean, I'm not taking anything away [from this season] -- I'm not trying to ignore the year and say it wasn't a big deal," Burnett said of his career-high 15 losses. "It was a big deal."
He hasn't pitched since October 2 and was a miserable 1-7 with a 6.61 ERA in his final 12 starts.
"I haven't pitched in a long time, so I haven't struggled in a long time," Burnett said. "I feel like I'm where I need to be. It's been a long time since I've been on the mound, but I'm sharp and I expect things to go as 'normal A.J.'"
Burnett was 1-1 with a 5.27 ERA in five postseason starts for the Yankees last year, but pitched to a 1.86 ERA in his three outings in the Bronx.
"If you can understand it and really look at it and be honest with yourself, [you can learn from it]," Burnett said of his rocky season. "I don't ponder too much about what happened, but I've got a pretty good idea why. The thing is, it's the playoffs. It's October. So it brings the best and the worst out."
Burnett actually had some success against the Rangers this season, as he was 1-0 with a 2.50 ERA in three starts against them. For his career against Texas he is 4-3 with a 3.66 ERA in 12 games (11 starts).
No matter how Burnett pitches, though, New York's bats are going to have to be better than they were against Cliff Lee in Game 3 on Monday. Lee added to his spotless playoff resume and continued his mastery of the Yankees by outdueling postseason stalwart Andy Pettitte in Texas' 8-0 Game 3 victory.
Josh Hamilton's two-run homer in the first inning spotted Lee (3-0) with an early lead, and that was all the left-hander needed, as he tied a career-high with 13 strikeouts and allowed only two hits and one walk over eight innings for the Rangers, losers of 10 straight postseason games to New York before a Game 2 victory on Saturday.
The Rangers have homered in all eight postseason games, longer than any streak they had during the regular season.
"Any time you can get that deep in the game and not give up any runs in the postseason, that's huge," Lee said. "Josh hitting that home run in the first made things a lot easier, that's for sure."
Over the past two seasons, Lee has quickly established himself as the standard for pitching prowess in the playoffs. Texas' midseason acquisition became the third pitcher in MLB history to win his first seven playoff decisions and is the first pitcher with three games of 10-plus punchouts in one postseason.
Hamilton added a double in the ninth to jump-start a six-run inning that turned a two-run game into a lopsided rout.
Pettitte (1-1), unbeaten in his previous nine postseason starts, was sharp despite a 10-day rest between outings, yielding only five hits with no walks in seven innings for New York, which has dropped only two games at home the last two postseasons. Lee was the winning pitcher in both, with the other coming in Game 1 of the World Series while he was with the Phillies.
"We've played three great games and we can't wait to get the next game going," Rangers catcher Bengie Molina said. "It's a great feeling knowing [Lee's] going to spot the ball where you ask him. He's a dream come true for catchers. He's an amazing pitcher."
The Yankees have managed to hit just .194 so far in the ALCS and have struck out 30 times through the first three games.
Hoping to give the Rangers a two-game advantage this evening will be righty Tommy Hunter, who will be making his first-ever Yankee Stadium start.
"It's probably going to be loud," Hunter said. "I would expect it to be. You know, it's a baseball game. That's what these other guys keep telling you; all of us young guys. We probably have the youngest bullpen ever in the ALCS. I mean, probably. You know, just being out there with those guys, being out there with [Darren] Oliver, he pretty much says, 'It's just another game.'"
Hunter was 13-4 in the regular season, but was charged with the loss in Game 4 of the ALDS against Tampa Bay, as he allowed three runs (two earned) and six hits in four innings.
Hunter has faced the Yankees twice and is 0-1 against them with a 6.75 ERA.
"I mean, you know, there's a lot of tradition. Everybody knows that," Hunter said. "There's 20-some-odd world championships that have been won here. Everybody knows that. We would like to win our first. So you've got to go out there and you've got to play baseball, and as soon as you step in between the lines, it's still a game. You've just got to block it out."
ALCS Game 4: Rangers Rout Yankees, 10-3, Take 3-1 ALCS Lead
ALCS Game 4 Reactions: The Search For Answers


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text:
Q: Swap columns with text and photos (html, css and php) I am making a website that shows a grid of photos with a little description on the left or right side of the photo. I want that the side that the text appears every time changed, so when you have Photo1 the text is on the left and Photo2 has the text on the right. Now is the case that it need to read out the images, and the text files from a folder, so I used php to get here. Now is my question, how do I get the php right, so it shows what I want it shows?
My code right now (its a little messed up):

<?php
$dirname1 = "../images/text/";
    $text = scandir($dirname1);
    $dirname = "../images/images/";
    $images = scandir($dirname);
    $ignore = array(".", "..");
    foreach($images as $curimg){

        if(!in_array($curimg, $curtext, $ignore)) {

    echo "

";
        }
    }

?>

And here is the codepen I found, that swaps the divs:
Codepen
Someone who knows a way to achieve this or make my code work, thank you already!!
(and thanks for your time)
EDIT:
i want something like this:
    <?php
  $dirname = "images-9/images/images/";
  $dirname1 = "images-9/images/text/";
  $text = scandir($dirname1);
  $images = scandir($dirname);
  $ignore = array(".", "..");
  foreach($images as $curimg)($text as $curtext){
          if(!in_array($curimg, $curtext, $ignore)) {
      echo "

            <img src='".$dirname.$curimg."'

but I know that this code won't work. Is there a way to get this working?

A: Use the ordering built into bootstrap, all you need to do is toggle between the 2 class names.

<link rel="stylesheet" href="https://cdn.jsdelivr.net/npm/bootstrap@4.6.0/dist/css/bootstrap.min.css" integrity="sha384-B0vP5xmATw1+K9KRQjQERJvTumQW0nPEzvF6L/Z6nronJ3oUOFUFpCjEUQouq2+l" crossorigin="anonymous">

      1

      text

      2

      text

      3

      text