text:
July 31, 2003 Columns » Letters
I just finished reading Cara DeGette's Public Eye titled "Keeping Score" from the July 17-23 Independent. I just wanted to say how wonderfully written I thought it was. It shows the stupidity of Focus on the Family (and people such as Focus executives Mike Haley and Bill Maier) in a humorous way, while still giving us the factual play-by-play of the closed mindedness of Focus on the Family. I enjoyed it thoroughly, and don't plan on missing future pieces from DeGette, or the Independent. Great job!
-- Blake Suboticki
I enjoyed the article of your cover story "Anxious for the Apocalypse" [July 17-23]. It amazed me that some of the evangelical Christian groups have the end of the world coming again. In the year 2000 the end was here, did we all forget that! Before this, different dates throughout the 1900s were the end of time! It is like these people pick out a date and when nothing happens (they were wrong) run to Kinko's for a new sign with a new date printed on it. Fear is a powerful tool.
When did the war that the United States and England wage become a religious war? We tell other countries that there is no such thing as a religious war. But since we are Christian, we are better than any other faith and a religious war is OK. Nice to have dual standards on your side, isn't it?
I am sad to see part of the Christian community wanting a war based on religion ... wanting the end of all time to come. Maybe some of these groups need to read the Bible again in its true form.
It has to be a sad day when the angels have to look down upon us and see humanity, an angelic creation itself, wanting to kill one another over a difference of opinion, because of a religious belief.
-- Rev. Gary Fearn, D.D.
Truth is dangerous
Thanks for publishing the article "The FB-eye may be watching" by Marc Schultz (July 24-30).
In a more perfect union, everyone who read the article would have gone to the Web site that Marc mentioned, http://charlotte.creativeloafing.com/newsstand/2003-06-04/news_cover.html.
It is news like this that warms the oddly named "cockles" of my heart. It is also one of the sites I try to avoid. Not because it isn't true, but more because "I can't take the truth," to paraphrase a line from a recent movie.
And truth like that is dangerous. No wonder the FBI came a- callin'. Someone out there is getting away with telling the people what is really going on in our government. They must be stopped. Or at least intimidated, bullied or threatened.
In my case, the pent-up fury at our government makes my blood boil and my bile rise. This aggravates my ulcer, I aggravate my spouse and someone ends up punishing the dog for making a mistake on the carpet from all the shouting.
Just remember, on the one hand, I, like many loyal Americans, have been sticking my head in the sand for too long.
On the other hand, isn't that better than sticking it up George W.'s pathetic posterior?
-- W. Dean Morgan
Making gun nuts happy
Let's be thankful we have a city council that sees to it the paranoid mentally ill and fanatic gun nuts feel comfortable and included in our community. Their policy of allowing lethal weapons of all types, unconcealed, concealed and partially hidden, in their own meetings, our public buildings, city parks, etc. ensures these sometimes marginalized groups can feel reassured packing heat everywhere.
Unfortunately some people are bothered by this progressive policy. Of course, whining is being heard from the usual enemies of freedom -- citizens attending City Council meetings regarding zoning changes, teachers wanting to take their students on field trips to city hall, golfers at city courses, parents with their kids at public pools and old people using our parks.
These wimps think that some of our armed citizens may get pissy and actually start firing some of their weapons, maybe blowing away innocent bystanders. This is not New York City. Thank goodness our City Council is brave enough to stand up to these pressure groups even though it might make it difficult for some people to vote for them next election.
-- Mike Maday
My wife and I visited Colorado Springs this past Saturday. Just before taking off on Saturday night, after numerous delays caused by a thunderstorm, my wife hit the restroom and came out with a lovely gold bracelet she had found on the floor. The airport was empty but for the handful of people on our flight. There was no authority around to give the bracelet to so we took it with us and committed to calling the airport police upon our return home. We did so and were told by your airport's finest that there was no point in reporting the found bracelet as several days had passed and no one would claim it by now. Wrong answer. We want to get this lovely piece of jewelry back to its owner. Would you please publish this note and invite its owner to e-mail us with a description? We'll take care of the rest. As for the airport security guy, find a job that does not require you to care about people.
-- Jeff Munks
Monterey, Calif.
jjmunks@attbi.com
I had the pleasure of visit in your fair city and Southern Colorado in early June. I recently received a copy of your paper containing the Ludlow story ["Almost like they massacred them again," June 26-July 2]. This was a great piece and I applaud you for it. I visited Walsenburg, Ludlow and Trinidad.
I am a member of the cemetery board for the Union Miners Cemetery in Mt. Olive, Ill. It is the only union-owned cemetery in the United States. It is also the grave site of and monument to "Mother" Jones. It was her request to be buried with "her boys," the slain miners of Mt. Olive [cemetery] at the Virden Coal Mine Riot of 1898.
-- Nelson Grman
Staunton, Ill.
Lynch mob mentality
Patrick Henry is attributed with saying, "I disagree with everything the man says, but will defend to the death his right to say it." I strongly admire his stance and his succinct example of free speech. Personally, I am too much of a wimp to be a defender of a member of the Ku Klux Klan -- a position that haunts me little -- my heritage as a bleeding heart social worker -- a mere cork bobbing in a sea of conservatives.
I speak for myself and thousands of Iraq war protesters of the bruising when we are called unpatriotic (or even worse, traitors!) by many from the right. We love this country and the rights with which we are blessed to speak our minds, and actively debate the different sides of complex issues and facets exceeding the boundaries of our labels.
Having recently viewed documentaries of the growth of the Third Reich, it was easy to see the progress of tyranny in which German rights atrophied until a dissenting opinion was met with imprisonment or a firing squad. I have concern that the tragedy of 9/11 has sown the poisonous fruit that Benjamin Franklin pondered with his alarm over the vulnerability of the Bill of Rights "if we can keep them."
My alarm bell goes when Dr. Hanan Ashrawi, a Palestinian spokeswoman, is greeted with a lynch-mob mentality, Arab-Muslims are detained without probable cause and jailed for months without charges, or a commencement speaker is threatened with physical violence for opposing the latest war. We now have a government with its so-called PATRIOT Act and a small-minded president who has sold himself to corporations (as Jim Hightower said, "He'll leave no millionaire behind"). We have much more to lose domestically from our passivity, unquestioning and silence than Saddam Hussein's myth of mass destructions.
-- Jim Sears
I think the vast difference in compensation between the victims of 9/11 and those who die serving their country in uniform are profound.
No one is talking about it, as you don't criticize anything to do with 9/11.
I can't let the numbers pass, as they say something disturbing about the entitlement mentality of this country.
If you lost a family member in the 9/11 attacks, you are going to get an average of $1,185,000. There is a guaranteed minimum of $250,000, [and the amount goes] all the way up to $4.7 million.
If you are a surviving member of a soldier killed in action you first receive a death benefit check for $6,000 (half of which is taxable). Next you get $1,750 for burial costs. If you are a surviving spouse, you will get $833 a month until you remarry. Then there's a monthly payment of $211 for each child under 18 years. This stops when the child reaches 18.
Meanwhile -- some people getting that $1 million to $4 million are complaining that it's not enough.
Some of the victims of the Oklahoma bombing are starting an organization to get the same deal the 9/11 families are getting.
Some families of persons in the bombed embassies are now asking for compensation also.
You see where this is going? It's just really sad.
By the way, the highest civilian medal is solid gold but the Medal of Honor is only gold-covered bronze. For shame.
-- Bob Steiner
Workers take a hit
On June 30, Democratic senators and House members urged President Bush to withdraw his proposal that would eliminate overtime pay for millions of workers. Overtime pay cuts being pushed by Bush and congressional Republicans are slated to go into effect for millions of workers as early as September.
Under the guise of helping workers have extra hours with their families, Bush and Republicans are trying to strip away workers' guaranteed rights to cash overtime pay, and [it] is just another example of George Bush working to help Big Business at the expense of working families.
Nearly 80 percent of all workers are in jobs that qualify them for overtime pay, which is time-and-a-half for each hour that is worked beyond the 40-hour week. Under the Bush scheme, millions of salaried workers making between $22,101 and $65,000 who now are eligible to receive overtime pay could be reclassified as executives or administrative employees and would no longer qualify for that type of payment. You would think that an administration that has presided over the loss of millions of jobs might want to strengthen the protections of workers fortunate enough to still be employed. But that's not what the Bush administration is about.
In addition to Bush's attacks, Republican Senator Judd Gregg's Senate Bill 317 would allow employers, under certain circumstances, to pay overtime only after an employee works 80 hours over a two-week work period. Workers who work 50 hours in one week for example, would not receive any overtime pay if they worked no more than 30 hours the following week.
The quickest way to determine whom Bush's proposal really helps is to note who is supporting it. Groups that represent business such as the U.S. Chamber of Commerce, the National Federation of Independent Business, the National Retail Federation and the National Council of Chain Restaurants applaud the proposed changes while groups that represent workers are opposing them.
Call Bush and tell him to leave your overtime pay alone.
-- Steve Plutt
Reader: The short and long of renting


android / platform / frameworks / base / 699b977^! / .
Revert "Update layoutlib following Change Id10ca97f on FontFamily"
Reason: The changes that this CL depends on, had to be reverted.
// TODO: support lang. This is required for japanese locale.
// variant can be 0, 1 or 2.
// collection. Typeface_Delegate may still hold a reference for it.


text:
/**
 * @file	stack.c
 * @author	Sunil Beta Baskar <betasam@gmail.com>
 * @date	2010-2012
 * @brief	A simple stack implementation.
 * @details
 *		This is a over-documented stack implementation.
 *		A lot of checks are in place to avoid
 *		memory errors.
 *
 */

#include <bkconfig.h>
#ifdef CONFIG_BK_DS_STACK

/* @remark betakit includes */
#include <memory.h>
#include <berror.h>
#include <btypes.h>

#include <stack.h>

/**
 * \verbatim
 * Incremental Stack / Design
 *
 * /------------\
 * | STACK_BASE | X
 * |------------|
 * | data ptr   | X  + PTR_SIZE
 * |------------|
 * | data ptr   | ...+ PTR_SIZE
 * |------------|
 * | data ptr   |
 * |------------|
 * | STACK_TOP  |
 * \------------/
 *
 * \endverbatim
 */

/**
 * @fn	stack_init *stack_init( t_u32 depth )
 * @brief initializes a stack
 * @param depth		maximum depth of the stack
 * @return pointer to stack on success or NULL on failure
 */
t_stack *stack_init( t_u32 depth )
{
  t_stack *stack_ptr = NULL;

  if( ZERO == depth )
    {
      return( stack_ptr );
    }

  stack_ptr = mem_alloc( sizeof( t_stack ) );

  if( NULL == stack_ptr )
    {
      return( stack_ptr );
    }
  stack_ptr->stack_status = STACK_UNKNOWN;
  stack_ptr->stack_depth  = depth + 1;
  /* @remark created stack but not ready */

  stack_ptr->stack_base = (t_ptr) mem_alloc( sizeof( t_ptr ) * (stack_ptr->stack_depth) );

  if( NULL == stack_ptr->stack_base )
    {
      stack_ptr->stack_status = STACK_ERROR;
      /* @remark cannot allocate memory for stack */
      return( stack_ptr );
    }

  stack_ptr->stack_top  = stack_ptr->stack_base;

  stack_ptr->stack_status = STACK_EMPTY; /* @remark stack is empty and ready */

  return( stack_ptr );
}

/**
 * @fn stack_depth( t_stack *stack_ptr )
 * @brief gets the maximum depth of the stack
 * @return ZERO on error, depth on success.
 */
t_s32 stack_current_depth( t_stack *stack_ptr )
{
  t_s32 retval = ZERO;

  if( NULL == stack_ptr )
    {
      return(retval);
    }

  return( retval = (stack_ptr->stack_top - stack_ptr->stack_base) );
}

/**
 * @fn stack_clean( t_stack *stack_ptr )
 * @brief cleans up a stack
 * @WARNING will clean up a stack even if it contains data
 * @return none (void)
 */
void stack_clean( t_stack *stack_ptr )
{

  if( NULL == stack_ptr ) return;

  mem_free( stack_ptr->stack_base );
  stack_ptr->stack_status = STACK_UNKNOWN;
  stack_ptr->stack_top   = (t_ptr)0; /* @WARNING DANGER! NULL Pointer */
  stack_ptr->stack_base  = stack_ptr->stack_top;

  return;
}

/**
 * @fn stack_push( t_stack *stack_ptr, t_ptr dataptr )
 * @brief adds an item to the stack
 * @param stack_ptr pointer to type t_stack
 * @param dataptr pointer to data pushed into stack
 * @return 0 on success and -ve on failure @see berror.h
 */
t_s32 stack_push( t_stack *stack_ptr, t_ptr dataptr)
{
  t_s32 retval = 0;

  if( NULL == stack_ptr ) return( retval = -(BERR_NOMEM|BERR_NORMAL) );

  if( STACK_FULL  == stack_ptr->stack_status ) return( retval = -(BERR_NOSPACE) );
  if( STACK_ERROR == stack_ptr->stack_status ) return( retval = -(BERR_CRASH) );

  if( (stack_ptr->stack_top - stack_ptr->stack_base) <= stack_ptr->stack_depth )
    {
      if( STACK_EMPTY != stack_ptr->stack_status )
	{
	  stack_ptr->stack_top++; /* @WARNING Pointer arithmetic */
	}

      *(stack_ptr->stack_top) = dataptr;

      if( (stack_ptr->stack_top - stack_ptr->stack_base) <= stack_ptr->stack_depth )
	{
	  stack_ptr->stack_status = STACK_READY; /* @remark STACK is ready */
	}
      else
	{
	  stack_ptr->stack_status = STACK_FULL; /* @remark STACK is full */
	}
    }

  return( retval );
}

/**
 * @fn stack_pop( t_stack *stack_ptr )
 * @brief pops an item out of the stack
 * @param stack_ptr pionter to type t_stack
 * @return pointer to data popped off the stack on success
 *	   NULL on failure.
 */
t_ptr stack_pop( t_stack *stack_ptr )
{
  t_ptr retval = NULL;

  if( (STACK_FULL  == stack_ptr->stack_status) ||
      (STACK_READY == stack_ptr->stack_status) )
    {

      retval = (t_ptr)(*(stack_ptr->stack_top));

      if( (stack_ptr->stack_top - stack_ptr->stack_base) <= stack_ptr->stack_depth )
	{
	  stack_ptr->stack_top--; /* @WARNING Pointer arithmetic */
	}
      else
	{
	  *(stack_ptr->stack_top) = NULL;
	  stack_ptr->stack_status = STACK_EMPTY;
	  return( retval );
	}

      if( (stack_ptr->stack_top - stack_ptr->stack_base) <= stack_ptr->stack_depth )
	{
	  stack_ptr->stack_status = STACK_READY; /* @remark STACK is not full */
	}
    }

  return( retval );
}

#endif	/* CONFIG_BK_DS_STACK */
/* @remark end of file "stack.c" */

redpajama_set_name: RedPajamaGithub


text:
Haani is a 2013 Indian Punjabi-language romantic drama film directed by Amitoje Mann and stars Harbhajan Mann, Mehreen Kaleka, Sarbjit Cheema, Anuj Sachdeva, Sonia Mann and Rupan Bal. The film consists of two story lines set in the years 1964 and 2013. The two story lines are told non-linearly and are interwoven with use of match cuts and reflect the themes of love and commitment.

Plot
Haani is a story of love and commitment. Moving between 1964 and 2013, Haani is the story of the Jatts who are defined by their simplicity, honesty, courage, good looks and above all – for honoring their commitments lifelong, be it for love, friendship or even enmity. Canadian born and bred Harman comes to Punjab with his best friend Tony and to his shock realizes that he can see and talk to the spirit of his grandfather Ranjit who has not been visible to anyone since his death 50 years ago. Ranjit's spirit is still here in this world due to his promise to his lover, Sukhaan, that they would leave this world together. As the story unravels, we see that in the year 1964 Ranjit is a farmer and his best friend is Jagir. Ranjit is a widower with a 2 yr old son being taken care of by his maternal grandparents. Ranjit and Sukhaan meet and fall in love with each other. But those were conservative times and love marriages were taboo. A series of incidents later, Ranjit is killed and Sukhaan is forced to marry an army officer by her family and is widowed later. Destiny makes Harman fall in love with Preet – Sukhaan's granddaughter. They, too, face the same problems. But they have a happy ending helped by Ranjit's spirit and Sukhaan. Haani narrates the story of Ranjit and Sukhaan whose love reaches beyond the boundaries of death and how their incomplete love story is concluded by their grandchildren - Harman and Preet. A romantic saga spanning two generations, Haani tells the story of love, friendship and honor immortalized by commitment.

Cast
 Harbhajan Mann as Ranjit  Singh
 Anuj Sachdeva as Harman
 Sarbjit Cheema as Jagir Singh
 Rupan Bal as Tony
 Mehreen Kaleka as Sukhaan Kaur
 Sonia Mann as Preet
 Ashish Duggal as Gurjant Singh
 Gurdev Dhillon as Ramu Ghaint
 Sardar Sohi as Rashpal Singh
 Gursharan Mann as Harinder Singh

Soundtrack

The film's score and soundtrack were composed by Jaidev Kumar and was released by Saga Music in 2013. All lyrics were penned by Babu Singh Mann.

Accolades
The annual PTC Punjabi Film Awards 2014 for excellence in Punjabi cinema was held on 3 March 2014. Haani was nominated in 11 categories and won 5 awards i: One of the Best Films of 2013, Best Story - Amitoj Mann, Best Lyrics - Babu Singh Maan, Original Background Score - Jaidev Kumar and Best Actor in a negative Role - Ashish Duggal, Best Technical Award.

References

2013 films
Punjabi-language Indian films
2010s Punjabi-language films
Films set in 1964
Films set in 2013

redpajama_set_name: RedPajamaWikipedia


text:
The Adrenaline Rush Of CircusTrix
We have a unique way that we lay these parks out, marked by openness and a real heavy emphasis on the details, on the aesthetics of the park. So when people walk in, they feel like they are somewhere special. That's been our calling card in the industry.
Why do we crave adrenaline? Think of all the dumb things people do to feed that burning desire to feel adrenaline course through their veins, a river of white-hot electricity taking them higher than any drug or drink. We jump out of airplanes with nylon parachutes attached to our backs, trusting that they will deploy and allow a graceful descent to the ground far below. We buy motorcycles and drive them haphazardly at breakneck speeds, judging that the feeling of screaming down a highway at 120 mph outweighs the risks involved. We longboard down narrow canyons, ski down steep mountains, and raft down monster rapids — adrenaline drives our behavior because once you taste its sweetness on your lips, very few things can compare.
So where do adrenaline junkies turn for their fix in 2016? There are obviously plenty of options, but one option in particular has been making waves in recent years — extreme recreation parks, where one can jump, zip, and fly to their heart's content, basking in the super-charged experience of an adrenaline rush.
Case Lawrence, founder of CircusTrix, used to work in real estate. After deciding he wanted to work in anything but real estate, Lawrence visited a trampoline park in San Francisco (one of the first parks in the world) and realized the vast opportunity available within the industry. Trampoline parks are a far cry from real estate so Lawrence willingly accepted the challenge, moved to Utah, formed a team, and in 2011 created the first official CircusTrix park, Skywalk in Fresno, CA.
"That's how the whole industry was at the time, a really fragmented mom-and-pop type environment," Lawrence said. "Entrepreneurs were just making stuff up. There were a couple manufacturers, but you had to really dig down to find them, making trampolines on this scale for an indoor trampoline park environment. All the vendors were new and haphazard. The whole landscape was like the Wild West, just raw and rough and you really had to get your hands dirty to figure things out. It was tough but it was a lot of fun."
CircusTrix opened their second location in early-2012 — Defy Gravity in Durham, NC — and buoyed by the success, Lawrence and his team began concentrating on building more and more parks. Each park is built based on a specific vision, one that is exclusive to each location — each has an original name, each contains original artwork and color scheme, each has a layout personalized to that location.
Like a sculpture whose work is shaped by their materials, CircusTrix also customizes each park based upon various factors, working closely with architects, muralists, and trampoline manufacturers to design the best experience possible.
"For these parks, we start with an existing building 90% of the time," Lawrence said. "So you're working with what you have, trying to transform this building that used to be a grocery store or ice skating rink. So we're trying to take what we have and work with it to make the best park we can. It's creativity in its ultimate manifestation. We found that we have a lot more to work with if we have a fresh brand for every one of these parks in each regional location. We've got a whole stable of brands and names for each of these parks and they're unique to that location. This really helps us to put up a fence and create a local following on social media for that park."
In the beginning, these indoor locations were run strictly as trampoline parks, large buildings filled with trampolines where a person could bounce and leap for days on end. As demand has risen for more ways to grab that adrenaline rush, CircusTrix has shifted to an extreme recreation park approach, exploring new tactics to corner the thrill-seeker market.
"When we first started doing these, they were 100% trampolines," Lawrence said. "Now, our latest and greatest park is about 50% trampolines and 50% other attractions. We were actually the first one in America to roll out the Ninja Warrior obstacle courses and come up with an application in these trampoline park settings."
We all have that friend who watches Ninja Warrior and says they could complete each obstacle course, usually to the scepticism of anybody who knows them. Now that doesn't have to be speculation — take him/her to one of CircusTrix's recreation parks, then hope they fail miserably so you can make fun of them and constantly remind everyone of their inadequacies.
When you're done with the Ninja Warrior course, other options await. Who among us doesn't want to zip across slacklines suspended over foam pits? Who among us doesn't want to test our skills on the flying trapeze, or try to match the acrobatics of Cirque du Soleil performers using aerial silks and trampoline walls?
"We have a unique way that we lay these parks out, marked by openness and a real heavy emphasis on the details, on the aesthetics of the park," Lawrence said. "So when people walk in, they feel like they are somewhere special. That's been our calling card in the industry."
With 30 current locations and 12 more set to open in 2016, CircusTrix is now the largest owner and operator of recreation parks in the world. Lawrence plans on continuing this growth, stimulated by constant innovation and personalized parks, while still honoring that element of extreme recreation providing every adrenaline junkie with exactly what they need.
"The industry has grown like crazy and trampoline parks have driven this recreation renaissance in America," Lawrence said. "Miniature golf, arcades, outdoor go-cart tracks, that was kind of the old paradigm and in the last five years, this trampoline park industry that has emerged is driving a whole new paradigm. The landscape has changed so rapidly."
JF Capital Collaborates With Partner Fusion To Launch Brixio
They know tech, we know commercial real estate and we both want to do more than solve a problem, we want to create the future. We believe that future is Brixio. In most
Jane.com And Musana Join Together For #StrongLikeYou Campaign
Women around the world — but more specifically with this campaign, women in Uganda and women here in the States — they all want the best for their families. I am a pessimist. I wasn'

redpajama_set_name: RedPajamaCommonCrawl


text:
Endovascular Therapy Benefited Patients vs. Alteplase Alone in EXTEND-IA
Stan Grossman
The trial was stopped early for efficacy.
NASHVILLE — Among certain patients with ischemic stroke, endovascular therapy with the Solitaire Flow Restoration (FR) stent retriever led to improved reperfusion, early neurologic recovery, and better functional outcome compared with those who received alteplase alone, according to late-breaking trial data.
The EXTEND-IA trial was presented at the International Stroke Conference 2015. In the trial, Bruce C.V. Campbell, MBBS, BMedSc, PhD, FRACP, of the Royal Melbourne Hospital in Australia, and colleagues enrolled patients who were receiving 0.9 mg of alteplase per kilogram of body weight less than 4.5 hours after the onset of ischemic stroke.
According to study methodology, patients had occlusion of the internal carotid or middle cerebral artery and computed tomographic (CT) perfusion imaging indicated salvageable brain tissue and ischemic core of less <70 mL. Patients were randomly assigned to receive either endovascular thrombectomy with the Solitaire FR stent retriever (n=35) or to continue with alteplase alone (n=35).
Reperfusion at 24 hours and early neurologic improvement — defined as at least an 8-point reduction on the National Institutes of Health Stroke Scale or a score of 0 or 1 at day three — were the coprimary endpoints. Ninety-day modified Rankin functional score was a secondary endpoint.
After randomization of 75 patients, the trial was stopped prematurely due to efficacy.
Campbell and colleagues reported a higher rate of ischemic territory that underwent reperfusion at 24 hours in the endovascular therapy group (median, 100% vs. 37%; P<.0001).
Rates of early neurologic improvement at three days were also higher with endovascular therapy (80% vs. 37%; P=.002), which was initiated at a median of 210 minutes after stroke onset. Additionally, the rates of functional outcome at 90 days were increased in the endovascular therapy arm, with more patients achieving functional independence, which was defined as modified Rankin scale score of 0 to 2 (71% vs. 40%; P=.01).
Rates of death (endovascular, 9% vs. alteplase, 20%; P=.18) and symptomatic intracerebral hemorrhage (endovascular, 0% vs. alteplase, 6%; P=.49) did not significantly differ between groups.
In an interview with Neurology Advisor, Albert Favate, MD, chief of vascular neurology and assistant professor of neurology at NYU Langone Medical Center in New York, said the EXTEND-IA trial confirms that thrombus extraction with the Solitaire device is beneficial over tPA alone.
"However, the concurrent use of tPA may also limit any thrombus formation in collateral supply," he said. "The limiting factor in use of tPA is that once clot size approaches 8 mm, immediately tPA will only work 1% for clot dissolution. EXTEND-IA supports the need for use of thrombolytic and mechanical extraction with the Solitaire."
Favate added that the number needed to treat (NNT) in the EXTEND-IA and MR. CLEAN trials to have a positive effect was 3 patients. "The NNT for IV tPA alone in the first hour of arrival with treatment is 6.5 patients, so, by comparison, combined treatment with tPA and intra-arterial clot extraction is far superior as demonstrated in the NNT [analysis]."
For more coverage of the International Stroke Conference 2015, go here.
Campbell BCV et al. Late-Breaking Trial #2. Presented at: International Stroke Conference 2015; Feb. 11-13, 2015; Nashville, Tennessee.
Campbell BCV et al. N Engl J Med. 2015; doi:10.1056/nejmoa1414792.
Close more info about Endovascular Therapy Benefited Patients vs. Alteplase Alone in EXTEND-IA