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Sponge's Vinnie Dombroski
Detroit's comeback kid plows ahead
by Brian McKinny, senior editor
Vinnie Dombroski is very important to the history of rock and roll in Detroit, Mich. As the front man of no less than three working bands — Sponge, Crud and the Orbitsuns — his vocal talents and force of personality seemingly know no bounds. Unlike the city from which he hails, Dombroski is accustomed to making strong comebacks.
by Steve Sergent
He's an original member of Sponge, which realized almost instant success with the 1994 debut of "Rotting Piñata," a must-have album for any aficionado of early '90s alternative rock. Catchy songs such as "Plowed" and "Molly (16 Candles Down the Drain)" boosted the album — that had heavy rotation on MTV and flooded the alt-rock radio airwaves — to Recording Industry Association of America Gold status.
After a lengthy hiatus, Sponge is back with the new "Stop the Bleeding" album, a new tour and a lot of the same old attitude. Based on the album title, you might think Sponge has suffered some great defeat or injury, but nothing could be further from the truth.
Recently, I was fortunate enough to sit down and talk with Dombroski, the sole remaining original member of the band, about everything from his humble beginnings as the son of a gigging guitar player and guitar teacher in Detroit, to his thoughts on the state of the music industry today. We discussed his touring with Sponge in support of their latest release and one of his favorite side gigs as singer and guitarist with the Orbitsuns, an eclectic and entertaining amalgamation of country and rockabilly with a modern-day twist.
McKinny: How old were you when you got into music? Was guitar your first instrument?
Dombroski: Yeah, guitar was my first instrument. Then I switched to drums, which I stuck with, and it eventually led, in a roundabout way, to my singing with Sponge. My dad taught guitar. He was a gigging musician, so there was always a guitar around the house, but it wasn't like I took lessons from my old man or anything like that. At 12 years old, I was writing my own songs and playing my own music.
Later on, when I was out there gigging, playing drums, I had a band called Loud House. I played the drums, and I did a lot of the songwriting, and because I wrote most of our songs, that morphed into playing guitar and singing with Sponge.
McKinny: Growing up in Detroit when you did, you must have been exposed to the punk and glam scene at the time — Iggy Pop and The Stooges, MC5, The Meatmen. Who were some of your earliest influences?
Dombroski: The old Motown R&B music was ingrained in my brain. The Galaxy 500 with the AM radio blasting the Motown stuff — and that's good stuff to have ingrained into you. That's what I remember being my earliest exposure to music.
McKinny: You mentioned playing drums in your previous band, Loud House. How did you end up singing and transforming the band into what is now Sponge?
Dombroski: I had come off the road with another band, I was back in town, and a bass player and a guitar player were looking for a drummer. It looked like the singer wouldn't be around much longer, so when I jumped on board, they were ready to audition a singer. When that singer came down and auditioned, we knew we had something good going on, which turned out to be the beginning of the Loud House thing.
We ended up doing a record on Virgin, and in the process of trying to make a second record, the singer quit. Since we all had participated in the writing, we decided that we'd look for a singer but record a demo at the same time, and I ended up singing on the demo. After recording the demo, we decided that we had enough strong songs that instead of finding a singer, we should just look for a new drummer. So by default, I ended up being the singer of what became Sponge.
McKinny: What was it like for you to make the move from being behind the drums to being out in front of the band? Was that a difficult transition for you or was it a natural progression?
Dombroski: I can't recall a real problem with making the transition. It was more of a means to an end. We had these songs, they sounded damn good, and somebody had to sing this shit. So yeah, man! Let's go! Also, it was kind of hard for us to find a singer that we would have collectively been happy with, because the original singer was a special kind of guy, and it just would have been very difficult to move on with something like Loud House. So with Sponge — the new songs, the new direction, and me jumping out front to sing the new stuff — we didn't miss much of a beat.
McKinny: Once Loud House ended its run, how did you come up with Sponge as the band's name?
Dombroski: That was a name on a list of many names at the time, and we had whittled it down to two names right before a show we were doing just outside of Detroit. The show's promoter came up to us and said, "What name am I putting up on the marquee? What are you guys calling yourselves?" We said, "Well, some of us like the name The Electric Cattle Gods." You know, because that was cool! The other name we had was Sponge. The promoter said he didn't have enough letters to put The Electric Cattle Gods on the marquee, so we told him to put Sponge up there … From that point on, our name was Sponge.
McKinny: What was it like to have such quick success with Sponge after working so hard to find success with your previous groups? How did you deal with the sudden change of fortune?
Dombroski: The only thought that comes to mind from back then was "go." Keep moving forward, roll with the punches, don't look back, don't be apprehensive. We knew we had some pretty strong songs, and I think we felt that it was just a natural progression that we would have success, not only on MTV, but on the radio as well. Radio was changing like crazy back then, and based on the strength of a song like "Plowed," we thought that it was a slam-dunk!
However, when the song was first written and recorded, it wasn't as if we sat there going, "Oh, man. This is gonna be a radio smash!" But with the alternative format emerging the way it did, we were of the mind that, "Hmm, this is working, and this will continue to work!" So yeah, you could say that we were fired up and ready to go at that point.
McKinny: Where did you record your album, "Rotting Piñata?" Was it there in Detroit or somewhere like LA or NYC?
Dombroski: That record was already halfway in the can before Sony signed us and got involved. We were well on our way to getting it done. We recorded it in Saline, just outside Ann Arbor, Michigan, on our own dime. Sometimes, it's the best way to do it, and that's how we're doing it today. You reap more benefits, but you take all of the risk, too. There's always risk.
McKinny: "Have You Seen Mary?" a track from your album, "Wax Ecstatic," was included in the soundtrack of Kevin Smith's movie "Chasing Amy." Before that, "Seventeen" was included on the "Mallrats" soundtrack. What was your relationship with Kevin Smith, and how did that come about?
Dombroski: From what we understood, Kevin was a big fan of the band, and we were happy to provide the music because we were fans of Kevin Smith! I met him at the "Mallrats" premier, many years ago.
McKinny: Have you licensed music from Sponge or any of your other bands for use in commercials, TV or movie projects?
Dombroski: I have another group I play with here in Detroit, called Crud. Crud's music is sought after for TV shows like "CSI," and we've been approached by many TV and movie people interested in licensing our music from the two albums that Crud released. We've been very lucky with that. Early on, it seemed like there was a lot of money in music licensing. Today, the work doesn't seem as plentiful as it used to be, because these days, everybody wants to license music for movies, TV, commercials, whatever. There's a ton of bands out there who own their own masters, because there aren't as many bands involved with major labels anymore. There's a lot more competition in the music licensing market today than 10 or 15 years ago. However, if you own your own masters, and you own the publishing (rights), it can be pretty sweet.
McKinny: How do you deal with publishing and copyright issues? Have you maintained the rights to all of the music you've written over the course of your career?
Dombroski: Sponge is the most complicated group to license. Fortunately, for us, even though guys who used to play in the band and aren't in the band anymore have ownership in the publishing, we all still speak to each other and are on good terms. So as long as we're all still speaking, and we can get people to sign off on things, it's a relatively simple process. The easiest stuff is if there are no other co-writers or people with publishing interests to license something from a band like Crud or the Orbitsuns, where I write the majority of stuff. There may be other co-writers on some of the tracks, but because it's so streamlined with one writer who owns the publishing, it's a very simple process.
McKinny: Sponge has experienced several lineup changes over the years, and you are the sole, remaining original member of the band. How have those personnel changes affected the sound of the band and the music you write?
Dombroski: Yeah, I'm that last guy standing! Although, the guys currently in the group have been with the band for about a dozen years now, so a lot longer than the original lineup stayed together. We've managed to keep the sound of the band while trying out different things over the many albums that we've recorded.
As for writing music, the process … Back when the band first started, there was a group of guys in a rehearsal studio — it was really just an empty storefront with a PA system. It was all about ideas. The best ideas, of course, are the ones that get the most attention. We would know very soon whether an idea would work or not, and if something didn't work, we'd move onto something else quickly. So, that process made a lot of sense.
Then, it began to change, even with the original members, as they began to give me tons of cassette tapes with snippets of guitar riffs or whatever, and I'd go through everything. It kind of morphed into just three of us getting into a room and working on material and listening to tapes; eventually it got down to just two of us original guys (laughing), and it was the two of us in a room, working on stuff. Then, the responsibility fell onto my shoulders.
When I get together with the group now, I'll have something that I've been fleshing out — a good idea of what I want to do when we get into the rehearsal studio — and then we'll work on it, refine it and get it done. When we're ready, we'll record it. But where I think it's changed the most is that it used to be a group of guys in a room, and now I'm working out of the house and then taking the music into the rehearsal studio.
McKinny: Do you write when you're on the road?
Dombroski: The ideas always come, you know. I'll get some good ideas for lyrics out there, and I'll write them down. And most likely, a melody goes with it, so I get pieces, bits and pieces of ideas that I'm always jotting down. But that can happen anywhere; it can happen on a drive, a walk or cutting the grass. It happens all the time. You just have to be available for it. Writing on the road happens. But writing happens everywhere. It's not as if we get too many quiet opportunities these days; you really have to find the time or make the time, especially when you have all these external distractions. You have a smart phone in your hand or an iPad. It's a challenge to block out all those things.
McKinny: It's a big responsibility to be the writer of most of the material for a signed, working band. Do you ever get to the point where you just need to get away, blow off some steam? Maybe go off to some secluded place and just write?
Dombroski: Oh, man! That would be great to do stuff like that. I think the last time I tried to do something like that was in Tucson, Arizona, at a place called Club Congress back in the 90s. I thought, "I'll get something done here!" But the problem was the place had a bar downstairs, so you think you'll write some great stuff, but after you go back over the stuff you did, you see it wasn't quite as good as you remembered it … Let's just say that I can't recall writing a big hit song when I was bombed.
And you know, I do get help. Our bass player, who's produced three, four of our records — Tim Patalan — he's not just a bass player; he also owns the Loft Studio in Saline. He's been a big ally, getting together and fleshing out the big ideas in the studio, so help is at hand.
McKinny: You're married with children. How do you handle that and a life on the road?
Dombroski: Oh yeah, married again, yes sir. Five kids total. I have a good wife, and I can lean on her to maintain, keep things on the level here at the house. It's all time management and trying not to forget about happy hour occasionally, you know (chuckles)?
McKinny: How has getting back into the swing of things with Sponge — a new album, touring — affected your commitments to your other bands, Crud and the Orbitsuns? How do you coordinate things like gigs, studio time, rehearsals and everything else that goes on between the three bands?
Dombroski: Crud plays just a handful of gigs a year. The Orbitsuns have been very busy up until the time the Summerland Tour started, have been over to the UK, did a whole tour there a couple of years back. That band can play anywhere, anytime — we don't need a lot of production. It's a lot of fun, and we play a lot of places. But right now, it's a priority thing. I think that Sponge deserves my focus right now, and there's a lot of good stuff going on, so I'm hunkering down, really trying to focus on Sponge stuff. I love to do the Orbitsuns dates — squeeze them in between. But there will be a time here, probably early next year, when we'll focus on a brand new Orbitsuns record.
McKinny: Regarding the Orbitsuns, what made you decide to start writing country songs? It seems quite the contrast from Sponge, and your industrial band, Crud.
Dombroski: That started probably around the time we did "Wax Ecstatic," with the song, "Drag Queens of Memphis." Prior to 1996, all these huge bands — Hank Williams, Jr., my first wife who was from Georgia played bluegrass music, so having the great country music around and understanding the greatness of it, the fans revering it — I couldn't help but write the stuff. And I think that if you write songs, you just can't pigeonhole yourself. For example, I wouldn't take an Orbitsuns' song and put it on a Sponge record, nor would I put a Crud song on a Sponge record. The songs always keep flowing and to not mix up the entities, I've recorded the stuff. I won't put it on a Sponge record, but I still want to record them — they're good songs. Four records down the road with the Orbitsuns and a lot of songs, a lot of gigs under our belt, it's been a great time, it's been a great ride with that group, and it's been an awesome and very natural thing to do.
However, these days with country music sounding like rock music, it just seems like the next place to go with it would be to do a stomping rock/country record, and who better to do it but some rock dudes from Detroit? Why not? Jack White's doing his country thing, and there's Kid Rock doing his thing, Hank Williams the Third, so why not some Detroit guys?
I think it's one of those things that we're all faced with these days, a lot of us just love the traditional-style country music. There's some kind of connection between the old-school style country music and the rock attitude; although, the instrumentation of it might be different. I think that's why so many of us can relate to the country. We can relate to the rock. I mean, you take out the pedal steel and the fiddle, but lyrically speaking there's a lot of things that are very similar. It's no wonder why a lot of us guys do both.
McKinny: Aside from the genre differences, what are some of the major differences, such as the performance dynamic, between Sponge and the Orbitsuns?
Dombroski: I think the Orbitsuns can be more unscripted than Sponge. When you have a group like Sponge and go out and play "Plowed," people want to hear the version on the radio. I'm relatively comfortable playing those songs the way they are, night after night, after night.
With the Orbitsuns, it's just a wild card! The gigs can last three hours, easy. And we can field requests from people, so the show isn't scripted at all. We've got a basic outline, but it's always different. Tempos can be different, instrumentation is different, but at the end of the day, no matter how we present it, it's still all good because of the strength of the songs. I think the freer the performance is, the more the audience appreciates it. It can't be phoned in, and that's one thing that won't work with us, because it's just phony. We can't be that way. We just came off a nine-week tour with the Summerland dates, and even though we were tired, people paid to see us, and we'd make sure they got their money's worth! So why rip off anyone by giving our audience a phoned-in show?
McKinny: I've been wanting to see your band, the Orbitsuns play live. Have the Orbitsuns ever done a national tour, or do you just do regional shows and European dates? What are some of the obstacles to doing a U.S. tour?
Dombroski: I think it's just based on having a record out there. We have some friends, the Deadstring Brothers and Whitey Morgan and the 78's, both bands from Detroit signed to Bloodshot Records, and they keep real busy. So we know we have the keys to the highway when we need it. But Sponge is certainly the priority. But who knows with the Orbitsuns; the songs take you to the craziest damn places, so we'll make the record and go where the songs lead us.
McKinny: Are you endorsing any company's products? What's your equipment poison?
Dombroski: (Laughing) I'm one of those guys that has never been able to take advantage of the whole endorsement thing. I think the last endorsement people put in my hands was American Guitar Company, who were bought out by Gibson. But I've played the same damn amp since '96, which is a silver-faced 1972 Fender Twin Reverb without the master volume that turned white many years ago. That amp was smashed on a video shoot, and I got it running again. It's just a great sounding amplifier. My guitar is a Fender Esquire (a variant of the popular Fender Telecaster model) that was kind of hot-rodded out by Joey Mazzola from the old Sponge band. I acquired it after he smashed it back in the '90s, so between that guitar and amp, that's pretty much my stuff.
McKinny: What about effects?
Dombroski: Nothing but straight in, man! Nothing but the cord between my guitar and my amp. And when you turn that thing on with that hot little pickup in there, it just sounds like hell on earth. It sounds great, man! You know, what I heard when Steve Jones recorded with the (Sex) Pistols, was that he was using a Les Paul into a Fender Twin. I kind of believe that, because of the hot little pickup in that Fender of mine — I guess it had a Humbucker pickup in there originally, but when you plug that into a Fender Twin Reverb, it sounds badass.
Still, most of your sound is in your hands. When I look at guys who use a ton of effects to get their sound, to me it just seems like a crutch. I just prefer things simple; I know a lot of guys don't like that. I think the more wiring you have in between your guitar and your amp chokes your signal.
McKinny: Have you experimented with your sound over the years, or did you just find a combination that works for you and stick with that?
Dombroski: Oh yeah, I took the original speakers out of my cabinet and put in a pair of Celestion speakers to give it a little more distortion, but the amp wouldn't go up loud enough, and it was too distorted. Then I pushed over and started using the Epiphone with the master volume on it, but that didn't bite enough — it was too warm-toned — so I reverted to the Fender Twin Reverb with the hot-rodded Esquire.
McKinny: How do you mike your rig when you're recording?
Dombroski: All we've really ever done is take an SM-57 microphone and drop it in on the center of the cone. Sometimes we'll try a room mike, just to see what the room mike will do, but that's about the extent of any crazy miking with my rig. I prefer to keep things simple.
McKinny: What are your thoughts on the music business today? With the advent of social media, YouTube viral videos and the like, where do you see the industry headed? How have you adapted to the many changes the industry has undergone these last several years?
Dombroski: Going back to the heyday of MTV and modern rock radio, if you look at those two factors, they were simple, they were powerful, and they worked. These days, the equation is not as simple. People get their media through so many different channels in their respective toolboxes now, so they aren't exclusive to the record labels anymore. I think there's an upside to that. You can go to CD Baby or get your record out on iTunes, but the big trick is getting people to be aware of your music.
A lot of groups go out on the road, and the big challenge is that gas ain't cheap, hotels ain't cheap, and the club business has always been hard. I think it's more difficult than it's ever been, but bands have Facebook, Twitter and all these ways to communicate that we didn't have back when we were starting to gig out. We'd pull into Columbus, Ohio and be on the lookout for the nearest Kinko's before hitting the club to print out fliers to put on everybody's car windshields before the gig – that's what we would do.
Nowadays, with Facebook, you can be just as powerful as a radio station. Ask people at a club today, "How did you hear about the show?" They'll tell you, "Facebook!" They weren't even aware of the fact that a radio station had been pumping ads for the gig all week. So the biggest change to the industry in the last several years has been social media; how bands are using it to get their product out and people to their shows.
McKinny: On a related subject, has your profit margin changed for the better or for the worse since the record companies aren't as involved as they once were? Are you seeing more money come your way since you're doing more on your own?
Dombroski: We've learned how to do it, despite the fact that we're not with a major label. Back in the day, when we were with a major label, I didn't make a dime on the road. I mean, we were paying for all our crew, the buses, hotels — paying for everything and not putting anything in our pockets at the end of the day. Your agent takes a cut, your business manager takes a cut, and everybody takes a cut. Plus, back then, everybody needed to be in their own hotel rooms, all the comforts of home on the road, to stay out there on the road for a long time, and maybe it's understandable.
Instead of getting the bus loaded up, now we'll take the van and share hotel rooms again. People don't want to do that kind of shit, and I can't blame them, but if you want to keep playing, you have to learn how to streamline and do the best you can with what you have. We've learned how to make it all work for us over the years, and we've had to adapt quickly. Those who don't adapt to the changes in the industry starve and die. You couldn't survive, and we did what was necessary. We're always adapting to the power shift, more so now than ever. Whether it means we're using backlines from an opening band because it costs too much to pull a trailer around the country, or maybe we'll just bring a snare drum. I mean we're using the trailer a lot less because it doubles the cost of our gas. So that's what we do.
McKinny: Bands usually either love or hate the road. Regardless of how you may feel, touring is a business necessity, more so now than ever before. Do you still enjoy touring, or has it become something of a necessary evil that you have to endure?
Dombroski: Nah, I enjoy it, I definitely enjoy it. I enjoy it when I'm able to, as stupid as this may sound — we were on a bus for nine weeks, which is OK, but the bus travels at night, and I never sleep well in a moving vehicle. NEVER. Never have, never will. So my idea about going out on the Summerland Tour was to get in a sprinter bus/van and drive. I like to drive; I love to be able to enjoy the scenery — that's when I enjoy touring, when we can stop wherever we want, when we want.
But on this particular tour, it was tough to sleep in the bus, and we weren't able to see a lot. My idea was to get hotel rooms, sleep at night, and travel during the day. That's what I hoped to do, but what happened was I'd get tired, you know? Tired from not sleeping for nine weeks. Yeah, go figure, right? But I had a blast, a great band, a great situation, people treated us very well, but you just get tired. What the fans don't see on stage and what they may not appreciate fully is all the work and preparation that goes into putting on shows. They may not realize that because when we hit the stage, it's all about putting on the best damn show we can, no matter how tired or sleep-deprived we may be from the road, and that's our job, our commitment to them.
McKinny: Once your current tour with Sponge is complete, what do you have in store, and what are some of the things you'll do that you're looking forward to the most?
Dombroski: Well, I've just been focusing so much on the Sponge stuff and trying to ramp up the record, so I've been very preoccupied with all of that. But really, I'd like to co-write some music with some folks — get out there maybe next year in the spring and begin to write with people, some country music folks like Jamie Johnson, who've worked with people like George Strait, Willie Nelson. That's about as ambitious as I am right now.
You can find Sponge's latest album, "Stop the Bleeding" on iTunes
For the latest news and tour dates for Sponge, click HERE


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Q: JSoup extract href of a tag that has rel attribute I want to extract a href attribute of   tag that has rel tag also.
This is the div portion that I work on it.

I tried with the following code but it didn't give me output I want :-
Elements itemimg = doc.select("article").select("div.post-thumbnail");

Elements rel = itemimg.select("a[rel~=bookmark]");

//System.out.println(itemimg);
System.out.println("It 's"+rel);

}

This is the output sample (I want the hyperref:/....... only).

If I use the following code , I will get the first hyperlink only and I want  all hyperlinks.
http://www.sfqat.com/deals-12153-%d8%b9%d8%b1%d9%88%d8%b6-%d8%a8%d9%8a%d8%aa%d8%b2%d8%a7-%d9%87%d8%aa-%d8%ba%d8%af%d8%a7%d9%83%d9%85-%d9%86%d8%b5%d9%87-%d8%b9%d9%84%d9%8a%d9%86%d8%a7/
Document doc = Jsoup.connect("http://www.sfqat.com/deals-9580-%d8%a7%d9%84%d8%b7%d8%b9%d9%85-%d8%a7%d9%84%d9%84%d8%a8%d9%86%d8%a7%d9%86%d9%8a-%d8%a7%d9%84%d8%a3%d8%b5%d9%8a%d9%84-%d9%8a%d8%b5%d9%84-%d8%a5%d9%84%d9%8a%d9%83-%d8%a3%d9%8a%d9%86%d9%85%d8%a7-%d9%83/").get();

Elements art =doc.select("article").select("div.lop").select("span.lop1 a[href]");
Elements itemimg = doc.select("article").select("div.post-thumbnail");

Elements rel = itemimg.select("a[rel~=bookmark]");
System.out.println("It 's"+rel.attr("href"));

A: Use it:
Elements rel = itemimg.select("a[rel~=bookmark]").attr("href");

A: Try this instead:
Document doc = Jsoup.connect("http://www.sfqat.com/deals-9580-%d8%a7%d9%84%d8%b7%d8%b9%d9%85-%d8%a7%d9%84%d9%84%d8%a8%d9%86%d8%a7%d9%86%d9%8a-%d8%a7%d9%84%d8%a3%d8%b5%d9%8a%d9%84-%d9%8a%d8%b5%d9%84-%d8%a5%d9%84%d9%8a%d9%83-%d8%a3%d9%8a%d9%86%d9%85%d8%a7-%d9%83/").get();

// Extract links
Elements links = doc.select("article div.post-thumbnail a[rel=bookmark]");
for(Element link : links) {
   System.out.println(link.attr("abs:href"));
}

// Extract images
Elements imgs = doc.select("article div.post-thumbnail a[rel=bookmark] img");
for(Element img : imgs) {
   System.out.println(img.attr("abs:src"));
}

//Extracting Hrefs and images adjacently.
Elements links = doc.select("article div.post-thumbnail  a[rel=bookmark]");
Elements links2 = doc.select("article div.post-thumbnail img");
for(Element link : links) {
   for(Element link3 :links2) {
      System.out.println(link+"\t"+link3.attr("abs:src")+"\t"+link.attr("abs:href"));
   }
}

Instead of calling multiple times the select method, the method is called one time only with a single selector expression: article div.post-thumbnail a[rel=bookmark].
You can test your selector expressions here: http://try.jsoup.org.
You can even fetch directly any url.
For details, the documentation for selector expression is here: http://jsoup.org/apidocs/org/jsoup/select/Selector.html

redpajama_set_name: RedPajamaStackExchange


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EHR series slurry pumps are similar to those within the EHM series in structure. What differentiates the EHR from the EHM is the material of wet parts, which is either a natural rubber, chloroprene rubber or another wear-resistant rubber. EHR slurry pumps are more suitable in delivering strong corrosive or abrasive slurries of small particle size without sharp edges.
Both the frame plate and cover plate has an outer casing made of either grey cast iron or ductile cast iron, depending on the working pressure. A split structure and bolts connected ensures security and easy replacement of the wet parts.
Interchangeable anti-corrosive wet parts are made of natural rubber or other customized elastomer materials.
There are various drive types: DC (direct connection), V-belt drive, gear box reducer, hydraulic couplings, VFD, SCR control, etc.
The shaft seal uses the packing seal, expeller seal and mechanical seal.


text:
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StartUp Health Insights, the data arm of the New York health technology accelerator, StartUp Health, recently published its year-end funding report. It highlights trends in investment and the highest venture capital rounds raised by health tech companies. The report takes a broad view of digital health, including companies "that enable health wellness and the delivery of care through data/analytics, sensors, mobile, internet-of-things, 3D printing, genomics and personalized medicine." It also includes acquisitions and IPOs. For this edition of Pulse Extra, StartUp Health provided a customized breakdown of the 10 largest rounds raised by New York–area companies.
Local digital health companies received nearly $2.6 billion in funding last year, more than double their $1.1 billion total in 2017, which was fueled by several massive rounds. The top 10 deals alone totaled almost $1.8 billion. Peloton raised the largest amount, $550 million, to support sales of its exercise bike and on-demand fitness classes. Health insurer Oscar raised two large rounds, worth $375 million and $165 million, with Google's parent company, Alphabet, taking a larger stake.
Butterfly Network, which sells a mobile ultrasound system, raised $250 million in September in a round led by Fidelity with contributions from Fosun Pharmaceutical and the Bill & Melinda Gates Foundation.The company is based in Guilford, Conn., and has a New York City office.
Other companies that landed large rounds included pharmacy company Capsule and CipherHealth, which offers digital tools to help providers share information internally and engage patients.

redpajama_set_name: RedPajamaCommonCrawl


Don't forget the special organ recital with explanations of organ construction, operation and tuning from Richard Young and Organ music played by Mike Sole. This will be on our unique 3 manual organ.
This organ recital is free and all are welcome. There is a retiring collection and a light lunch of soup and rolls can be purchased from 12 noon.
Clifton Road Chiropractic Centre generously supported Project Welcome by entering a team in the Rugby Half Marathon back in July. In the picture above Sheila is receiving the money raised by Pete Sawyer and the rest of the team: just over £400! Thank you so much everyone who took part, either running or donating.
and if you would like to donate please click on the link below.
St Peter and St John Church are holding a special organ recital with explanations of organ construction, operation and tuning from Richard Young, an award winning local organ builder with a national reputation for organ restoration. Locally he has restored organs at Leamington Hastings, the organ at St Matthews and St Oswald's and the organ at Ansty.
Organ music will be played by Mike Sole a well known musician, organist and keyboard player from Leicester. This will be on our unique 3 manual organ incorporating parts from Holy Trinity Church organ which, before demolition was at the top of Railway terrace in Rugby.
This organ recital is free and all are welcome. There is a retiring collection and a light lunch of soup and rolls can be purchased from 12 noon onwards.
We have tidied the Veg beds today and put in some celeriac and leeks. It'll be a while before these are ready, meanwhile over the next few weeks there will still be some runner beans coming along, lots of tomatoes will ripen soon and you can help yourself to herbs.
Bobby Dog was not much help!
FREE FRESH VEGETABLES AVAILABLE from the edible garden at St Peter and St john church. Ready to pick now:runner, french and broad beans, spinach, beetroot, lettuce and tomatoes.
Some of our 8 o'clockers enjoyed a visit to Betty who moved away in March to live nearer to her daughter. Sheila took Pat, Janet and Minnie over and we enjoyed coffee and lunch together. Wonderful to see Betty again - she's wondefully funny and seems to have settled in really well. Thank you for lunch and the biscuits, Betty.
Thank you everyone for your hard work completing the Choir Vestry 'make-over'.
Started in July by a group of young people from 'The Challenge' who got a lot of the painting underway, we have since had several working parties to complete the painting.
Yesterday, August 8th, a new carpet went in and the new curtains went up, both made possible by very kind donations from church members.
We also got the entrance hall painted (another coat still needed, hopefully done later this month) and the toilet by the back door.
The idea behind this makeover is to create a more pleasant environment for course to be held such as the Life Course as well as for the regular services and meetings for which we use the room.
Just a bit of more clearing up and putting stuff back in place and we'll be all done. Fab job everyone.
Who let the dog in? Bobby admires the new look vestry: walls, carpet and curtains.


This documentary about ballet bad boy Sergei Polunin lacks emotional punch but seriously delivers on the dancing.
In 2010, Sergei Polunin became the British Royal Ballet's youngest principal dancer ever. In 2012, he sensationally quit in a cloud of depression, drug use, and erratic behaviour. Dancer documents Sergei's rise from a childhood of poverty in the former Soviet Union to a glittering career as one of the greatest ballet dancers on earth.
Unfortunately this journey wasn't a happy one, with Sergei's family dispersing around the world to fund his ballet career, one that he says he didn't choose. He's angry at his mother for what he sees as her leaving him alone in London in his very early teens (she believes it to be her biggest sacrifice, having left in order to maintain Sergei's immigration status), and longing for his father, whom he didn't see for the 6 years following his mother's departure. Despite, and possibly because of, his astronomical success in one of the most well respected companies in the world, he eventually begins to feel restricted, and unable to purely and freely enjoy his passion, the wheels start to come off.
This should be gloriously dramatic and decadent given the subject matter, but the reality, as the documentary would lead us to believe, is rather… dull. It entirely skims over the myriad issues Sergei had, both with depression and drug use (he once tweeted asking if anyone knew a heroin dealer in the middle of the night) – there's a fleeting mention of him using cocaine before he goes on stage, but that's where it ends. There is a good deal of insight into his childhood and family, but we don't see how those events have affected him as an adult; Sergei Polunin is clearly a troubled man, but it feels as though the documentary, like most people in his life, doesn't really pay enough attention to what's making him tick.
There's some wonderful footage from his childhood, which shows how advanced and gifted Sergei was from as young as three. Even if you don't understand ballet, the sight of Polunin in a class pirouetting at five times the rate of his peers is incredibly impressive. The footage of him dancing as an adult is truly mesmerising, and this forms the most enjoyable part of the documentary – seeing Sergei dance. There is an irony, then, given his yearning for freedom, that the rest of Dancer isn't particularly interesting.
The saddest moments come from his father, Vladimir, who evokes real emotion, as he speaks of his regrets about his actions early in his son's career, his sadness at hearing an opinion on the news that Igor Zelensky (Sergei's mentor post-Royal Ballet, and father figure) had replaced him, and his pain at no longer being able to see the son he adored.
As the documentary moves into present day, there's a slightly contrived scene on the beach, where Sergei asks his school friend Jade Hale-Christofi to choreograph him a 'last dance' for a David LaChapelle-directed video, set to Take Me To Church. Said video, which is seen in full (and, it's worth mentioning, is absolutely breathtaking) went viral and currently has 18.7 million views on YouTube.
The whole thing just feels a touch too slow. You will it to pick up throughout the whole running time, and the points that should carry a huge emotional impact don't really land. The dancing, on the other hand, is beautiful, and that ultimately carries the documentary. It leaves you wanting to know more, to dig deeper, which would be a good thing, were it not for the fact that it doesn't really do so in the first place.
Dancer is available in UK cinemas and on VOD.


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S. Korea, US adopt flexible defense posture
Ulchi Freedom Guardian likely to be suspended
By Yi Whan-woo
South Korea and the United States are assuming a more flexible stance in their joint pressure against North Korea's military threats following the June 12 summit between North Korean leader Kim Jong-un and U.S. President Donald Trump in Singapore.
Seoul and Washington are discussing possible suspension of their joint military exercises, after holding onto a decades-long view that such exercises are a key element for their alliance and a deterrent against Pyongyang.
Analysts said Friday such a surprising change in the allies' security stance is to boost momentum for detente on the Korean Peninsula as witnessed at the Singapore summit.
In their reciprocal concession in Singapore, Trump said he would halt the Seoul-Washington military exercises, which Pyongyang has denounced as a "rehearsal for invasion," while Kim promised to destroy a testing site for intercontinental ballistic missiles targeting the U.S.
"The U.S concession is a small yet right step toward North Korea's security guarantee as promised by Trump," said Park Won-gon, an international relations professor at Handong Global University. "The two foes are expected to build their trust and help gain momentum for peace and denuclearization on the peninsula."
A senior Cheong Wa Dae official said Friday South Korea and the U.S. will announce a decision in the near future on whether to suspend the annual Ulchi Freedom Guardian (UFG) in August, adding the two sides have had discussions accordingly.
President Moon Jae-in Thursday also underscored a flexible change in military pressure and expressed his willingness to suspend the joint drills.
"Though nothing has been decided yet, we're going to announce a decision in the near future through close consultations between the South and the U.S.," the presidential official said. "We're going to continue to discuss the issue between the South and the U.S. and between the South and the North if necessary."
The official also said the U.S. and the North are expected to resume negotiations at an early date after the U.S. reviews the results of the summit with the North.
"Depending on the progress in those negotiations, we anticipate that talks about declaring an end to the war or replacing the armistice with a peace treaty will kick off at an appropriate time," he said.
Yang Moo-jin, a professor at the University of North Korean Studies, said he finds Cheong Wa Dae's step optimistic. "the North is expected to come up with more concrete step toward denuclearization," he said.
"This may also speed up efforts to sign a peace treaty to end the 1950-53 Korean War."
Seoul's Ministry of National Defense separately announced Friday a phone call the day before between Defense Minister Song Young-moo and U.S. Secretary of Defense Jim Mattis on whether to suspend the joint drills.
Harry Harris, a former commander of Pacific Command and the Trump administration's nominee for ambassador to South Korea, also supported suspension of the combined exercises, although he said North Korea's nuclear threat remains.
"Today, following the summit, we are in a dramatically different place," he said during the nomination hearing before the Senate Foreign Relations Committee, Thursday. "The whole landscape has shifted. I believe we should give exercises, major exercises, a pause to see if Kim Jong-un is in fact serious about his part of the negotiations."
He added that, for the first time in his career, the world is in a place "where peace is a possibility," although he stressed the sanctions on North Korea should not be lifted.
China has been concerned about U.S. military expansion in the Asia-Pacific and also called for suspension of the joint drills.
And Huanqiu Shibao, a Chinese newspaper under the auspices of the People's Daily newspaper, said the suspension of the drills will lead to "a fresh peninsula."
yistory@ktimes.com More articles by this reporter


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Well, for one, my carboholic self loves potatoes, but beyond that…reusable and recyclable packaging to minimize package waste is growing on the shopper radar, challenging the industry to innovate.
With a rising importance on taking care of our planet, shoppers are increasingly aware of our packaging choices and package waste.
Recent headlines have included shopper complaints about their mounting stacks of shipping boxes from online orders, criticizing Amazon and others for shipping items in multiple packages or excessively large boxes.
Early on, meal kit delivery companies were praised for their model focused on delivering convenience to the front door, but rapidly had to hear about the amount of packaging used to ship the product.
The amount of packaging is one consideration in produce merchandising, but shoppers, particularly organic shoppers, are also looking for better alternatives, such as environmentally-friendly (52%), resealable (49%), packaging focused on reducing food waste (47%) and reusable packaging (30%). Among organic produce shoppers, these numbers are significantly higher.
I was reminded of these stats a few months ago, when visiting a little produce store in my home town of Didam, the Netherlands. Instead of the standard roll of plastic bags, shoppers scoop their potatoes into pre-labeled paper bags.
Other companies call out 100% recycled plastic on their clam shells or use cardboard rather than plastic. In this competitive environment, highlight your efforts in environmentally-friendly choices, recycling efforts and package waste as one more way to differentiate your product or your store.


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'Health care is a right, not a privilege': Congressman Lewis on eradicating AIDS
By: Wendy Corona
Updated: Jun 27, 2016 - 6:56 PM
FULTON COUNTY, Ga. - Channel 2 Action News told you the CDC estimates one out of 51 Georgians will be diagnosed with HIV.
Now, Fulton County has laid out its plan to eradicate AIDS in Atlanta.
"The problem is real. We've become the capital of the growth of HIV and AIDS," Congressman John Lewis said.
Calling health care a right and not a privilege, Lewis supported Fulton County's task force in its plan to eradicate HIV/AIDS in metro Atlanta.
A Channel 2 Action News investigation revealed in May that researchers and doctors believe Atlanta is the epicenter of what they are calling an "epidemic."
"I grew up in the 60s and polio was an issue when I grew up, and no longer you hear about polio today and it's because of will and intentionality and we can do the same thing," said Chairman John Eaves with the Fulton County Commission.
WATCH: Atlanta's HIV 'epidemic' compared to third world African countries
Fulton County laid out its blueprint for creating education for schoolchildren and providing opt-out screening in all health care settings and jails.
"It's important to ask the question, do you want to be tested?" Eaves said.
In solidarity with the strategy and national HIV testing day, both Congressman Lewis and Chairman Eaves sat down and swabbed the inside of their mouths. Twenty minutes later their HIV statuses were ready.
"The key to prevention is to know your status," Eaves said. "It's this simple test the plan seeks to make readily available to all in 2015; the task force utilized nearly 35 million dollars of federal funding to stop the growth of HIV/AIDS."
"We need to spend more and more of our limited resources on health and not on bombs and missiles and guns," Lewis said.
Phase three of the plan to end AIDS in Fulton County is laid out, and the leadership said it believes the groundwork is there as an achievable strategy.
9-year-old electrocuted in family's backyard pool by broken underwater light


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Home › Headlines
Damn: Stevie J Is Heading To Jail
Stevie's Instagram post suggests he may be going away for a while.
@coupcoup40cal
Stevie J shared a cryptic Instagram message late Thursday night hinting that he may be about to serve some time.
The Love & Hip Hop: Atlanta star and former hitmaker for Bad Boy wrote, "Shout out to my real ones locked up… Bout to do this time starting next week. Sum thing (sic) light for this child support case."
It's not clear why Stevie is serving time over child support, or when he will be out, but he made it clear in his post that he is not a deadbeat: "My kids love me and I love them that's all that matters."
Stevie, government name Steven Jordan, has been battling his children's mother Carol Bennett over child support payments. In 2015, Stevie and Joseline Hernandez appeared in Manhattan federal court to answer for $1.1 million in back child support payments.
PHOTO CREDIT: Instagram, Getty
Damn: Stevie J Is Heading To Jail was originally published on globalgrind.com
joseline hernandez	, Love and Hip Hop Atlanta	, Stevie J


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ALL LATEST NEWS
ACES NO.1 FRICKE SETS HIS SIGHTS ON PREMIERSHIP TITLE
PAUL BURBIDGE
FIM Speedway Grand Prix star Max Fricke set his sights on ending Belle Vue's league title drought after sealing a return to the Aces for 2022.
The double Aussie champion is back in the SGB Premiership after his Polish club Zielona Gora were relegated from the PGE Ekstraliga.
With Falubaz now in the First Division, Poland's rules allow Fricke to race in two other leagues, and he will line up in Manchester, as well as competing for Swedish team Indianerna.
Fricke became a huge favourite among Belle Vue fans during his previous five-season stint with the club from 2015 to 2019.
The Victorian racer can't wait for what's set to be a busy 2022 season, and he would love to mark his Aces return by leading one of British speedway's most famous clubs to their first league title since 1993.
After being unveiled to the Belle Vue fans at the club's Christmas Cracker event, Fricke said: "My schedule for next year, even with the Grand Prix series, has opened up to give me the opportunity to return to the UK.
"My first thought was Belle Vue for many reasons and if the reaction of the fans at the Christmas Cracker is any indication, I think I've made the right choice.
"It is amazing to be back in Manchester with the Aces again. I'm somebody who likes to keep busy and this fits in perfectly with my commitment for next year.
"We've only confirmed two names so far, with myself and Charles [Wright] but there is an exciting vibe coming from the club already for 2022.
"I'm really excited about the team that Mark [Lemon] is putting together and hopefully it can be this team who can take that final step to win Belle Vue the Premiership title."
RETIRED SWC WINNER SUNDSTROM SET FOR SWEDISH U21 ROLE
HANCOCK: JANOWSKI SEEKING MAGIC MIX
HOLDER EYES FINAL PUSH FOR TIGERS
MADSEN'S DANISH HOMECOMING
THOMSEN: VOJENS INSPIRED BY 2021 TITLE HEARTBREAK
ACES SIGN GERMAN TEEN BLODORN


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–1786) – canon of the chapter of St [vol. 12, p. 100]
The horizontal line represents the person's life.1715 - born1786 - died
Dinouart, Anthony Joseph Toussaint
, canon of the chapter of St. Bennet at Paris, and member of the academy of the Arcades at Rome, was born of a reputable family at Amiens, Nov. 1, 1715, and died at Paris April 23, 1786. After exercising the ministerial functions in the place of his nativity, he repaired to the capital to engage in literary pursuits. M. Joly le Fleuri, at that time avocat-génral, gave him his esteem, his confidence, and his patronage. He was first employed on the "Journal Chretien," under the abbe Joannetj and the zeal with which he attacked certain authors, and especially M. de SaintFoix, involved him in some unpleasant controversy. He had represented this latter as an infidel seeking every occasion for mixing pestilential notions in whatever he wrote. SaintFoix took up the affair with warmth, and brought an action against both him and abbe Joannet, which terminated in a sort of reparation made him by the two journalists, in their periodical publication. After this the abbe Dinouart began to write on his own account, and in October 1760, set up his "Journal Ecclesiastique," or, Library of ecclesiastical knowledge, which he continued till his death. He | established a very extensive correspondence with the provincial clergy, who consulted him on the difficulties of their ministration. This correspondence contributed greatly to the recommendation of his journal, which contained instructions in all matters of church discipline, morality, and ecclesiastical history. The editor indeed made no scruple of drawing almost all his materials from well-known books, without altering a word; he inserted, for example, in his journal, all the ecclesiastical part of Hardion's Universal History; but it was useful to the inferior provincial clergy, who were deficient in libraries, and not sorry to have their loss in some shape made up by the periodical compilation of abbe Dinouart. Other critics censured him for giving an incoherent assortment of articles; for advertising, for instance, in the same leaf, "Balm of Genevieve," and "Sermons to be sold" for the use of young orators who would not take the trouble to compose them; imitating in this a quack of our own nation, who used to advertise sermons, marmalade, and rules for carving. Dinouart, however, bears a reputable personal character. He was naturally of a kind disposition and a sensible heart. The great vivacity of his temper, which hurried him sometimes into transient extravagancies, which he was the first to condemn in himself, prompted also his activity to oblige, for which he never let any opportunities escape him. He generally wrote in a loose, negligent, and incorrect manner, both in verse and prose, and even aspired to be thought a French and Latin poet; but still the usefulness of the greater part of his works recommended them. Among them, we find, 1. "Embriologie sacre'e, traduite du Latin de Cangiamila," 12mo. 2. "Hymnes Latines." 3. "Manuel des pasteurs," 3 vols. 12mo. 4. "La llhetorique du predicateur, ou Traite de l'eloquence du corps," 12mo. 5. A new edition of the "Abrege" chronologique de Phistoire ecclesiastique de Pabbe Macquer,"Paris, 1768, 3 vols. 3vo. 6." Anecdotes ecclesjastiques," ibid. 1772, 2 vols. 8vo, in which he was assisted by the abbd Jaubert. 1
Dict. Hist.
Dinarchus
Dingley, Robert (1619–1659)
Dinocrates
Dinostrates
Dinouart, Anthony Joseph Toussaint (1715–1786)
Dinus (?–1303)
Diodati, John (1576–1638)
Diodorus Siculus
Eachard, John (1715–1697)


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The BloghomosexualityReligion and PoliticsGay Marriage
Loving the Sinner, Hating the Sin
Baby steps. That was my reaction to the Easter weekend comments of Cardinal Dolan, the affable Archbishop of New York, about gays and the Church. I give the man credit for taking a more positive and welcoming tone. But it's also a sign of how low the bar is set.
John Corvino, Contributor
Author, What's Wrong with Homosexuality?
Apr 2, 2013, 08:46 AM EDT | Updated Dec 6, 2017
That was my reaction to the Easter weekend comments of Cardinal Dolan, the affable Archbishop of New York, about gays and the Church. Responding to a question about how he would respond to a loving same-sex couple, Dolan replied,
Well, the first thing I'd say to them is, 'I love you, too. And God loves you. And you are made in God's image and likeness. And -- and we -- we want your happiness. But -- and you're entitled to friendship. But we also know that God has told us that the way to happiness, that -- especially when it comes to sexual love -- that is intended only for a man and woman in marriage, where children can come about naturally.
Dolan went on to say that the Church must "do better to see that our defense of marriage is not reduced to an attack on gay people. And I admit, we haven't been too good at that."
He's got that one right.
I give the man credit for taking a more positive and welcoming tone, and sincerely hope that his fellow Christians take note. At the same time, it's a sign of how low the bar is set when comments like Dolan's inspire such interest and excitement. For example, Francis DeBernardo, Executive Director of the gay Catholic group New Ways Ministry, called Dolan's remarks "nothing short of an Easter miracle."
Really? Rising from the dead is an Easter miracle. Marshmallow Peeps are an Easter miracle. (You can put them in your pantry for a decade, and they won't decay. It's true.) But a Christian leader saying "Hey, maybe we shouldn't attack gay people"? That's just common decency, not to mention good strategy -- especially in a world where a majority of American Catholics support equal marriage rights for same-sex couples.
What worries me is that Dolan's remarks seem to be a kinder, gentler face on the same old "Love the Sinner, Hate the Sin" line. It's hard to argue with the "Love" part, naturally. But the sharp distinction between who we are and what we do -- the "sinner" and the "sin" -- doesn't hold up when we're talking about the fundamental relationships around which we organize our lives: our "significant others," to use a tired but illuminating phrase. Dolan's assurance that we're "entitled to friendship" seems a rather tepid consolation prize.
I explain my problem with "Love the Sinner, Hate the Sin" in the first of a series of 11 new short videos that I'll be sharing here over the next couple of weeks. The videos grew out of my new book, What's Wrong with Homosexuality?, and they counter common arguments against same-sex relationships in a concise, accessible, and occasionally funny manner.
The videos and book appear at a time when the justices of the U.S. Supreme Court are weighing arguments for and against marriage equality. Whatever happens at the Court, one thing is clear: Many Americans (including some justices and most archbishops) still believe that there's something wrong with being gay. In order to secure equality for all -- as well as to protect vulnerable LGBT youth -- it is important to counter such beliefs thoughtfully and forcefully.
homosexualityReligion and PoliticsGay MarriageVideolgbt
The 'Me Too' Movement Is Quietly Evolving Its Focus
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Wildly Interesting Celeb Interview Stories
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My Grandmother Taught Me Self-Liberation. Now I'm Ready To Pay It Forward.
Taylor Swift And Trans Model Laith Ashley Are A Dreamy Duo In 'Lavender Haze' Video
Sam Smith Recalls Being Spit At By Passerby After Sharing Their Nonbinary Identity
Anthony Rapp Reflects On Seasons Of Love And Loss In A Chilling New Show
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Ron DeSantis' 'Anti-Woke' Education Agenda Just Got A Big Boost
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Jonathan Knight Says He Was Told NKOTB Would Be 'Over' If He Came Out As Gay
Maren Morris Offers Teary Apology For Country Music's Lack Of LGBTQ Inclusion
These School Bans On Pride Flags Should Freak All Of Us Out
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'Banshees' And 'Everything Everywhere' Dominate 2023 SAG Award Nominations
My Eating Disorder Raged For Years. I Recently Relapsed — Here's How I Found My Way Back.
Emma D'Arcy Gave The Most Delightful Description Of Their Golden Globes Look
Golden Globes 2023: Here Are All The Winners
Here's How 'RuPaul's Drag Race' Stars Are Pushing Back Against Anti-LGBTQ Protests, Laws
A Gay Version Of 'Real Housewives' Is On The Way, And Twitter Has Thoughts
LGBTQ Rights Activist Edwin Chiloba Found Dead In Kenya
We Sold Everything To Travel The U.S. In An RV. There's One Thing We Never Expected.
Noah Schnapp Comes Out As Gay With Sweet 'Stranger Things' Allusion
Robin Roberts Reveals That She And Amber Laign Are Planning To Marry This Year
'Gay Conversion' Therapy Survivors Share Horrific Experiences In New Documentary
Meet The Affordable Sex Toys That You Can Get at Amazon and Target
Missouri Woman Could Be First Openly Transgender Woman To Be Executed In U.S.
Black Eyed Peas Spark Heat For Wearing Rainbow Armbands In Poland New Year's Event


How can I populate a backbone collection inside backbone-sync in a way that the resultant collection may be used outside the backbone sync.
My problem is that the input model doesn't get modified with the result array. How can I do that?
New data for collection will be available only after success callback because of asynchronous call in your case.
"How" to save an entire collection in Backbone.js - Backbone.sync or jQuery.ajax?
why return a jquery deferred object inside backbone sync?


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Cinematic Century
1962 – The Manchurian Candidate
By Patrick D Gaertner on November 11, 2018 • ( Leave a comment )
Looking ahead at the coming years of the Cinematic Century project I'm both pleased and stressed out to see that I have some incredibly difficult decisions in my future. Yeah, there'll be a couple of years with really clear-cut winners, but it seems like I'm entering a real storm of incredibly solid films, setting up a whole score of hard battles between some of the best films of all time. And, in theory, I think that today's year, 1962, should be one of those years. Because there are a handful of incredibly popular and beloved films that came out this year. But, while I really like most of these films, there was a clear winner to me as my favorite film. The biggest contender has to come from Lawrence of Arabia, one of the titans of cinema, and a film that frequently gets tossed up as one of the greatest films of all time. And, it's hard to argue with that. It's just not a film I'd call one of my favorites. It's an excellent film, but it's punishing length can often make it feel a bit like homework, something I appreciate wholeheartedly without really loving. Likewise, Stanley Kubrick's Lolita falls into almost the exact same category. There's a lot to appreciate about it, especially the insane hubris of adapting that novel at a time when the Hayes Code was freshly dead, but the film has never really worked for me. It brings the absurdity of the novel to it's most ridiculous extreme, but I think that the last remnants of the Hayes Code were enough to keep that film from being what Kubrick really wanted it to, holding it back. And, carrying on this trend we have To Kill a Mockingbird, a film that's certainly high quality, but one that I've never really found my self enjoying. The biggest rival for my favorite film of the year is probably a non-surprising choice, the very first James Bond film, Dr. No. I did spend an entire month of my life last year talking about the Bond movies and my undying love for them, and Dr. No is a pretty great entry into that franchise. But, things got better, and the growing pains that Dr. No feature keep it from taking the spotlight from what is undoubtedly my favorite film of 1962, the paranoid conspiracy thriller the Manchurian Candidate.
This film, like so many of the movies that I talk about during this project, was based on a very influential novel. Richard Condon's novel, despite later claims of plagiarism, was a very popular novel, with extremely topical subject matter that seemed to have its finger on the pulse of American politics. So, naturally, it was only a matter of time before the film got adapted. And, for reasons I couldn't quite find, it seems like the film's biggest champion, and the real reason that it was brought to life, was Frank Sinatra. The famous singer had been involved in quite a few movies at this point, predominately musicals, but he seemed deadset on bringing the Manchurian Candidate to the silver screen, earning himself a staggering amount of the film's budget in the process. He seemed incredibly involved in just about every process of the film, even some casting decisions, while getting perhaps the best role in the entire film as well. And, as we know, these sorts of passion projects can often fall on their faces. But, the Manchurian Candidate broke free of that curse, ended up being a massive success. It was released at the height of the Cuban Missile Crises, hot off the heels of the McCarthy Red Scare, and everything about it seemed as topical as could be. The film was very well-received, and has only gone up in esteem, reminding us that political conspiracies and fear-mongering are evergreen topics in America.
The film's story begins in the midst of the Korean War when a small platoon of American troops are attacked by some Korean forces. We aren't shown what happened, but things went bad for the Americans, and several days later all but two of the soldiers were rescued, all apparently thanks to Staff Sergeant Raymond Shaw, the most unlikeable member of the platoon. And, for his bravery Shaw is awarded the Congressional Medal of Honor, thanks in part to the recommendation of his commander, Captain Ben Marco. Shaw feels undeserving of the award, and his stature is immediately used by his scheming mother Eleanor and her power-hungry second husband Senator Iselin. Shaw resents his mother and step-father, and does his best to separate himself from them, going to work at a newspaper that frequently attacks Iselin. And, for several years it seems like things have reached a sort of status quo. Marco and the other surviving members of the platoon have no real memory of what happened in Korea, but they all seem to be wracked with the same nightmares. They're in a room full of old women discussing flowers, and things slowly start to point to the idea that they're being hypnotized by enemies, culminating in the hypnotists forcing Shaw himself to kill the two soldiers who died.
Marco is unable to convince anyone that the strange dreams he's having point to the fact that the Soviets did something shady to the platoon, and is eventually moved from his position in Army Intelligence to a safer position working with Senators. And this position puts him in contact with Senator Iselin, who has begun a shocking career as a Joe McCarthy-esque political figure, routinely railing against the evils of Communism while claiming to have iron-clad proof that a large, but ever-changing, number of Communists are working in the American government. But, this doesn't really affect Marco at first, instead he begins trying to find ways to convince his superiors that something suspicious happened in Korea, all while exhibiting some signs of PTSD. He eventually makes a small breakthrough though when a fellow member of the platoon reaches out with stories of the same dream, and both he and Marco are able to correctly identify some high-ranking Communist officials from the dream. So, Marco starts spending more and more time with Shaw, who we quickly realize has undergone severe hypnosis from a Chinese scientist. Shaw responds to the presence of a Queen of Diamonds while playing Solitaire, and will immediately do whatever task is presented to him following the view of the card, including the murder of those around him. And Marco eventually is able to discover this, and starts trying to help Shaw break his programming.
Things reach a real fever-pitch though when Mrs. Iselin starts planning for her husband to get nominated as the vice president. His greatest political rival is the father of Shaw's lost-love, and Mrs. Iselin starts plotting to get them back together in order to earn favor with her father. This backfires though, and Mrs. Iselin reveals herself to be a prominent figure behind Raymond's hypnotism, ordering him to kill both his love and her father, giving Senator Iselin no road-blocks to the vice presidency. However, after the murder of the love of his life, Shaw starts to agree with Marco that something is wrong with his mind, and the two work together to discover the power of the Queen of Diamonds, helping Raymond remove his hypnotism. But, in order to find out what his mother is planning, he continues to pretend like nothing is happening, until he gets his final orders. Mrs. Iselin wants Shaw to assassinate the man who receives the nomination of their party's president, right after Iselin is listed as the vice president. She thinks that that will then usher Iselin into both the nomination and then the office, letting the two of them take over the country and ramp up military spending in the country, in a concerted effort with the Communist governments to create a false Cold War to earn them perpetual power. But, Raymond isn't hypnotized at this point, and learns the whole plan. Marco then plans to take care of everything, arresting both Iselin's and ending the conspiracy, until the day of the convention arrives. Because Shaw has decided he needs personal revenge against the people who ruined his life, and ends up assassinating both Iselin and his mother. Marco attempts to stop Shaw after the assassination, and stands by as Shaw commits suicide, bringing the whole conspiracy to a close.
The Manchurian Candidate is an incredibly heavy movie. I'm frankly stunned that it was released in the 1960's, because at times it feels like it would be too explosive and inflammatory to gain real traction in the modern day, let alone so quickly after the actual Red Scare. I continue to be baffled at why exactly Frank Sinatra was so heavily involved in the making of this film, but I will say that, without a doubt, this is his finest performance. He was able to carry the film, something that should have been a challenge for even storied actors let alone musicians, and he brings Marco to life in a fascinating way, full of flaws, PTSD, and all manner of other ticks that we usually like to ignore from out heroic soldiers. Likewise, it's kind of hard to believe how menacing and frightening Angela Lansbury is as Mrs. Iselin, especially considering her future acting output. But she's legitimately one of the most diabolical and fascinating villains in cinema history, giving us a wonderfully twisted and ludicrous plot that is expertly handled by director John Frankenheimer. He's able to give create a film that grabs a hold of the viewer, bringing them on a frankly absurd journey and doing it in way that you never really question anything you're seeing.
Because America in 1962 was a very strange place. The film was actually released fairly shortly before the assassination of John F Kennedy, which has led to some seemingly false rumors that the film was pulled from distribution due to the shocking subject matter. It was made around the time of the Cuban Missile Crises. The world genuinely seemed to be at the brink of destruction. The Cold War was in full swing, and things were probably at their most dire they'd ever been. And, at least for me, this is the earliest film I've ever seen that tackles the bizarre horror of the Cold War. I'm sure there were other movies that looked at this unique conflict before this film, but the Manchurian Candidate examines it in a way that I still find utterly fascinating. Because it was a confounding time, full of double-crosses, spy-craft, and conspiracy theories. The Americans and the Soviets were engaged in a massive game of chicken, lying to each other and trying all manner of insane and tangential strategies to defeat the other, giving rise to any number of weird ideas. We had real life experiments like MKUltra going on, giving birth to literal generations of conspiracy theories. And this film seemed to tap into the ethos in a brilliant way. The film examines a lot of things wonderfully, especially the idea of Post Traumatic Stress on soldiers, but the way that it portrays conspiracies remains its most timeless factor. It shows a crazy scenario, and plays it out to its most dramatic extreme, creating a story that seems too absurd to actually happen. But, it probably wasn't too far off from reality. I'm sure there were attempts at making hypnotic assassins, I'm sure these sorts of coups were at least brain-stormed, and I'm sure the public would be swept up in the chaos. We're shown an analogue to the real-life horrors of the McCarthy-era of Congress, and given an example of how easily that could have gone down an even darker path, reminding us that anything is possible. So, this isn't exactly the most relaxing film to watch during the current nightmare that is geopolitics, but it remains depressingly and shockingly relevant.
The Manchurian Candidate was written by George Axelrod, directed by John Frankenheimer, and released by United Artists, 1962.
Categories: Cinematic Century
Tagged as: 1962, Cinematic Century, Cold War, Conspiracy, Hypnotism, John Frankenhaimer, Red Scare, The Manchurian Candidate
Issue 327 -"The Mystery of the Menacing Mask!"
Overlord and the Horrors of War


In the past 12 months, there has been a jump in the demand for financial analysts; however, there has been some is connect between what the real estate industry expects in regards to financial analysts and what actually drives and motivates today's analysts. RETS Associates conducted a 10 question survey among financial analysts ranging from entry level to senior analysts.
Most companies are expecting to hire analysts with one to three years experience; however, with the recent downturn in the industry, many recent graduates have been unable to procure positions that would provide them with the necessary experience.
The current state of the economy also effects what types of companies financial analysts are more inclined towards.
• As far as which industries are most appealing, generalist (mixed-portfolio) is the winner, followed by multi-family, office, retail and hotel/hospitality.
• Since 44% of analysts believe that it takes about two years to master the position, this expectation is not unrealistic, although obtaining this experience has been impossible for some graduates.


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Home » Canada » How to migrate from Singapore to Canada in 2021?
How to migrate from Singapore to Canada in 2021?
There are many reasons why many people wish to migrate from Singapore to Canada, it may be for a better future or looking for better job opportunities or for studying further or giving a better life to their families. There is good news for those wishing to move to Canada because the Canadian government has planned to welcome over a million newcomers between 2021 to 2023, the year 2021 is probably the best time to look at migrating to Canada from Singapore.In its immigration plans for 2021-23, Canada is planning to welcome 1,233,000 new permanent residents.
Another good news is that Canada does not distinguish between Singapore citizens and its immigrants when they apply for a visa to move to Singapore. Both have equal opportunities and equal chances of getting a visa provided they meet the eligibility criteria of the immigration program they choose to migrate to Canada.
Most applicants for migration to Canada apply for permanent residency or a PR visa because it provides them with various benefits which include:
The PR visa does not make you a citizen of Canada, you are still a citizen of your native country. As a PR visa holder, you can enjoy the following benefits:
Can apply for Canadian citizenship in the future
Can live, work and study anywhere in Canada
Eligible for healthcare and other social benefits enjoyed by Canadian citizens
Protection under Canadian law
Options to move to Canada from Singapore
There are several visa categories under which you can apply to move to Canada from Singapore, these include:
Express Entry program
Quebec Skilled Workers Program
Family class immigration
Business immigration program
To qualify under this program, you should be able to get a minimum of 67 points out of 100 in the eligibility factors given below:
Age: Those between 18-35 years get maximum points. Those above 35 get lesser points while the maximum age to qualify is 45 years.
Education: Under this category your educational qualification must be equal to higher secondary education under Canadian standards.
Work experience: For minimum points you should have at least one year full-time work experience. More years of work experience means more points. Your occupation must be listed as Skill Type 0 or Skill Level A or B of the National Occupational Classification (NOC).
Language ability: You must have at least 6 bands in your IELTS rest and the score must be less than 2 years old. You get extra points if you are proficient in French.
Adaptability: If your spouse or common law partner is willing to migrate with you to Canada, you are entitled to 10 extra points for adaptability.
Arranged employment: You can gain a maximum of 10 points if you have a valid offer from a Canadian employer.
The Canada Express Entry Program follows a points-based system for grading PR applicants. Applicants earn points based on qualifications, experience, Canadian employment status and provincial / territorial nomination. The higher your points, the greater the chances of having an invitation to apply (ITA) for permanent residency. Applicants receive the points based on a Comprehensive Ranking System or CRS.
Every Express Entry draw shall have a minimum cutoff score. An ITA will be awarded to all applicants with a CRS score equal to or above the cutoff score When more than one nominee has a score equal to the cutoff number, then the one with a longer presence in the Express Entry pool will obtain an ITA.
You do not require a job offer in Canada to apply under the Express Entry system. However, a job offer in Canada will increase your CRS points from 50 to 200 depending on the skill level. Canada's provinces also have Express Entry streams to help them select skilled workers from the Express Entry pool.
A provincial nomination will add 600 points to the CRS score which guarantees an ITA.
The CRS score keeps changing with every Express Entry draw which is held approximately every two weeks by the Canadian government.
However, you can move to Canada on a work permit and later apply for permanent residency. In order to get a work permit you must have a job offer in Canada. The type of work permit depends on the type of job you have obtained.
The Provincial Nominee Programs (PNP) was launched to help the various provinces and territories in Canada choose immigration candidates who are willing to settle in a given province or territory in the country and have the skills and abilities to contribute to the economic growth of the province or territory.
Every PNP targets the specific needs of the province's labor market. You can find a provincial stream matching your specific skills. To qualify for the Provincial Nominee Program (PNP) you must have the necessary skills, education, work experience and meet the language requirements.
Quebec Skilled Worker Program (QSWP)
This immigration program was started with the intention to encourage more immigrants to come and settle in Quebec without having to go through the hassle of a lengthy immigration process.
Through this program skilled workers can apply for the Quebec Selection Certificate or Certificat de sélection du Québec (CSQ). It is not necessary for applicants to have a valid job offer in order to migrate to Quebec. The QSWP is also based on a points-based system like the Express Entry System.
Business migration Program
Individuals interested in doing business in Canada can apply for a PR visa through the Canada Business Immigration Program. This program was designed to encourage migrants who can invest or establish a business in Canada. They must be high net worth individuals or must have either business or managerial experience to establish and run a business in Canada. The Canadian government has specified three categories of people for this type of visa.
Self Employed Persons
Individuals who are permanent residents or citizens of Canada can sponsor their family members for PR status if they are 18 years or older. They are eligible to sponsor the following categories of family members:
Conjugal partner
Common-law partner
Dependent or adopted children
Eligibility requirements for a sponsor:
Apart from being above 18 years and being a PR visa holder or Canadian citizen, a sponsor must:
Provide proof that he/she has the financial support to support family members or dependents
With the government's approval, he/she must agree to support the family members being sponsored for a certain amount of time
Must be residing in Canada or have the intention to live in the country during the arrival of the sponsored relative
The Canadian Experience Class or CEC program is aimed to help foreign workers or students who are staying on a temporary basis in Canada to become permanent residents. It considers their work experience or education and their contribution to Canadian society for granting PR status.
You can qualify for this visa if you have studied or worked in Canada and meet the minimum requirements. The other important eligibility requirements are:
12 months of work experience- either full-time or part-time in the past three years
Work experience must have proper authorization
Applicant must have plans to live in a province outside Quebec
Meet the language proficiency requirements
The immigration targets introduced by Canada till 2023 indicate the country's continued welcoming stance towards immigrants. This is the best time to try to migrate to Canada from Singapore through one of the various immigration pathways.
Canada, Singapore
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[X-Unix] Rotating the console logs?
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normal humans sleep at 3am at night, these tasks almost never get run.
You might want to set these to at a time when the system is actually up.


text:
Eva Hodgson Women's Basketball News & Bio
Name: Eva Hodgson
Hometown: Rindge, NH
High School: New Hampton School
Height/Weight: 5-9
Notes: Women's Basketball
Video: No. 19 UNC Women's Basketball Routs Virginia Tech, 71-46 - Highlights
The No. 19 North Carolina women's basketball team rebounded from their first loss of the season to rout Virginia Tech on Sunday, 71-46, in a...
Sun Jan 9, 2022
Video: Undefeated UNC Women's Basketball Cruises Past Alabama St., 83-47 - Highlights
The No. 25 North Carolina women's basketball team cruised to a comfortable 83-47 victory over visiting Alabama State on Tuesday afternoon in Chapel Hill to...
Video: UNC Women's Basketball Remains Undefeated With 76-73 Win Over Boston College - Highlights
The No. 25 North Carolina Women's Basketball team pulled off an impressive 4th-quarter come-from-behind victory to defeat Boston College 76-73 on Sunday in Chestnut Hill...
Sun Dec 19, 2021
Eva Hodgson, Carlie Littlefield Balance Basketball & MBA Studies
On the evening of Dec. 1st, junior Eva Hodgson scored 11 points off the bench to help the UNC women's basketball team earn a win...
Video: UNC Women's Basketball Holds Off Washington in Bahamas, 58-37 - Highlights
The North Carolina women's basketball team improved to a perfect 6-0 to start the season in the Tar Heels' 58-37 victory over Washington on Sunday...
Sat Nov 27, 2021
Women's Basketball Menu
UNC Women's BBall Schedule Roster Recruiting Tickets


Are there other Activity Maps to download or purchase?
Questions and Answers › Category: KUBO Hardware › Are there other Activity Maps to download or purchase?
As we expand our portfolio we will also provide new Activity Maps. We also plan to share Activity Map designs made by teachers. Remember to revisit KUBO.education every now and again to check for new free resources.


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Generate Dart-JS interop classes from a JS file.

This is an experimental tool to see how much information we can extract out of a raw JS library.
(For class-based JS libraries, it's looking pretty good so far)

# Installation

	git clone https://github.com/asgerf/dartify
	cd dartify
	pub get
	npm install

I suggest you add the following script to your PATH:

	dart DARTIFY/bin/main.dart $*

# Usage

	dartify FILE.js > FILE.dart

Open `FILE.dart` to see your generated API. Import from Dart and have fun!

# Examples

See the `testcases` for some example libraries.

For example see [fabricjs.dart](testcases/fabricjs/fabricjs.dart) and the [example code](testcases/fabricjs/main.dart).

# Runtime System

dartify's runtime system for JS interop is based on dart:js and is only a hack right now.
It should ultimately integrate more closely with dart2js, dart:js, or package:js.

Currently, values returned from dart:js are not wrapped in typed proxies. That needs to be fixed.

# Implementation

dartify combines heap analysis and static analysis on the AST.

The library is executed in a headless WebKit environment, and a heap snapshot is taken at the end of the top-level code.
At this point, all the classes are usually created and can be found in the heap.

Some tricks that are currently implemented:

- Names of parameters are taken from the AST.
- Detect redirect using `fun.apply(thisArg, arguments)`. Get parameter names from the effective target.
- Detect var-args if arguments array is used in a non-redirecting way.
- Detect instance fields based by looking for `this.x = E` in constructor.

Some things on the TODO list:

- Find top-level methods (i.e. things are not just static on a class)
- Find static and top-level variables.
- Infer optional parameters (maybe even names arguments).
- Infer types for parameters and return types in places where it's easy.

redpajama_set_name: RedPajamaGithub


Auto lock bottom, pre-glued before shipping out by us, fast product assemble on your end.
Tuck top, fast open style.
300gsm white virgin paperboard, thick enough to pack several tea bags.
Hot foil stamp of logo, UV shiny effect on the artwork.
Flat shipping, free design mockup for this box style.
This tea box uses white cardboard as a raw material, CMYK printing, Matt lamination, as well as hot stamping and partial UV treatment. The box cites a number of corporate design elements that allow customers to think of their brand as soon as they see the package.
Most tea boxes are made from cardboard because they are gifts. This package belongs to the retail packaging box, so the most cost-effective is naturally the paper card box. The unit price is only one-fifth of the gift box. In addition, the packaging material is recyclable environmentally friendly paper, and contribute to environmental protection with Shanghai BPS!
Tea packaging refers to the packaging of tea according to customer needs to promote the sale of tea products. A good tea packaging design can increase the value of tea by several times. Tea packaging is already an important part of the worldwide tea industry. This Custom Printed Organic Tea Packaging Box is well designed and free sample design can be applied to you, no matter you are new customer or our old friends.


text:
Nature's Afterlives with Gabriela Albergaria & Jorge Otero-Pailos
This exhibition brings together Gabriela Albergaria and Jorge Otero-Pailos, two artists whose work focuses on nature and the associated themes of growth and decay, history and memory, continuity and change.
Gabriela Albergaria (Portugal/UK) presents large-scale drawings and photographs of forest vegetation expose in meticulous, meditative detail complex natural structures.
The work of Otero-Pailos (Spain/U.S.) investigates the intersection of nature and architecture, using liquid latex as a form of building conservation technology that collects microscopic deposits of dust and human interactions in sheets of translucent rubber.
Together, Albergaria and Otero-Pailos seek to engage the viewer in the pattern, rhythm, and materials of nature.
Opening reception on November 13, from 6 pm to 8 pm.
Wed, November 13 —
Fri, December 20, 2019
Sapar Contemporary, 9 N Moore St, New York, NY 10013
Visiting hours: Tuesday–Saturday, from 11 am to 5 pm. Special event for Tribeca Art Night on November 14, from 6 pm to 9 pm. Extended opening hours on November 15: from 10 am to 8 pm
Sapar Contemporary
Presented by SAPAR Contemporary. Curated by Courtney Skipton Long, Ph.D., Acting Assistant Curator of Prints and Drawings at the Yale Center for British Art
Don't miss events like this one! Subscribe to our bimonthly newsletter to stay informed. Our subscribers also get exclusive access to select online content such as free screenings or concerts.
View our team at the Consulate General of Spain in New York.
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Not Only What, But Also How
Visions of Asturias in Washington, DC
La mujer del alféizar by Carmen Segovia
Pan y Circo by Axel Void
© 2011– 2023 Consulate General of Spain | 150 East 58th Street, 30th Floor | New York, NY 10155 | Tel: (212) 355-4080 | Fax: (212) 644-3751


text:
Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions
P. Ciotti, G. P. Pesce, F. Cafiero, M. L. Rainero, A. Sementa, G. Nicolò, G. S. Mela, M. Bagnasco, P. L. Santi, G. Bianchi-Scarrà
A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)
The expression of intercellular adhesion molecule-1 (ICAM1) and granulocyte-macrophage colony stimulating factor (GM-CSF) was investigated in 25 melanoma patients by evaluating 34 fresh biopsy specimens. ICAM-1 in situ hybridization and Immunochemistry for ICAM-1 and GMCSF were performed. Most of the metastatic melanoma samples (12 out of 18) and a few of the primary melanoma lesions (three out of 16) showed ICAM-1 expression. The expression of ICAM-1 was significantly (P<0.01) higher in metastatic lesions than in primary tumours. GM-CSF mRNA and protein were detected in 10 of the 18 metastatic samples and in two of the 15 primary lesions. A significantly high degree (P
Melanoma Research
GM-CSF
ICAM-1
Immunochemistry
In situ hybridization
Dive into the research topics of 'Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions'. Together they form a unique fingerprint.
Cutaneous Malignant Melanoma Medicine & Life Sciences 100%
Granulocyte-Macrophage Colony-Stimulating Factor Medicine & Life Sciences 76%
Intercellular Adhesion Molecule-1 Medicine & Life Sciences 76%
Melanoma Medicine & Life Sciences 36%
Immunochemistry Medicine & Life Sciences 19%
In Situ Hybridization Medicine & Life Sciences 13%
Biopsy Medicine & Life Sciences 8%
Messenger RNA Medicine & Life Sciences 8%
Ciotti, P., Pesce, G. P., Cafiero, F., Rainero, M. L., Sementa, A., Nicolò, G., Mela, G. S., Bagnasco, M., Santi, P. L., & Bianchi-Scarrà, G. (1999). Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions. Melanoma Research, 9(3), 253-260.
Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions. / Ciotti, P.; Pesce, G. P.; Cafiero, F. et al.
In: Melanoma Research, Vol. 9, No. 3, 1999, p. 253-260.
Ciotti, P, Pesce, GP, Cafiero, F, Rainero, ML, Sementa, A, Nicolò, G, Mela, GS, Bagnasco, M, Santi, PL & Bianchi-Scarrà, G 1999, 'Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions', Melanoma Research, vol. 9, no. 3, pp. 253-260.
Ciotti P, Pesce GP, Cafiero F, Rainero ML, Sementa A, Nicolò G et al. Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions. Melanoma Research. 1999;9(3):253-260.
Ciotti, P. ; Pesce, G. P. ; Cafiero, F. et al. / Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions. In: Melanoma Research. 1999 ; Vol. 9, No. 3. pp. 253-260.
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title = "Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions",
abstract = "The expression of intercellular adhesion molecule-1 (ICAM1) and granulocyte-macrophage colony stimulating factor (GM-CSF) was investigated in 25 melanoma patients by evaluating 34 fresh biopsy specimens. ICAM-1 in situ hybridization and Immunochemistry for ICAM-1 and GMCSF were performed. Most of the metastatic melanoma samples (12 out of 18) and a few of the primary melanoma lesions (three out of 16) showed ICAM-1 expression. The expression of ICAM-1 was significantly (P<0.01) higher in metastatic lesions than in primary tumours. GM-CSF mRNA and protein were detected in 10 of the 18 metastatic samples and in two of the 15 primary lesions. A significantly high degree (P",
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AU - Santi, P. L.
AU - Bianchi-Scarrà, G.
N2 - The expression of intercellular adhesion molecule-1 (ICAM1) and granulocyte-macrophage colony stimulating factor (GM-CSF) was investigated in 25 melanoma patients by evaluating 34 fresh biopsy specimens. ICAM-1 in situ hybridization and Immunochemistry for ICAM-1 and GMCSF were performed. Most of the metastatic melanoma samples (12 out of 18) and a few of the primary melanoma lesions (three out of 16) showed ICAM-1 expression. The expression of ICAM-1 was significantly (P<0.01) higher in metastatic lesions than in primary tumours. GM-CSF mRNA and protein were detected in 10 of the 18 metastatic samples and in two of the 15 primary lesions. A significantly high degree (P
AB - The expression of intercellular adhesion molecule-1 (ICAM1) and granulocyte-macrophage colony stimulating factor (GM-CSF) was investigated in 25 melanoma patients by evaluating 34 fresh biopsy specimens. ICAM-1 in situ hybridization and Immunochemistry for ICAM-1 and GMCSF were performed. Most of the metastatic melanoma samples (12 out of 18) and a few of the primary melanoma lesions (three out of 16) showed ICAM-1 expression. The expression of ICAM-1 was significantly (P<0.01) higher in metastatic lesions than in primary tumours. GM-CSF mRNA and protein were detected in 10 of the 18 metastatic samples and in two of the 15 primary lesions. A significantly high degree (P
KW - GM-CSF
KW - ICAM-1
KW - Immunochemistry
KW - In situ hybridization
KW - Melanoma
JO - Melanoma Research
JF - Melanoma Research