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Varsity Hockey Tournament Includes Harvey School
The Katonah-based Harvey School is among the varsity teams competing in the White Plains Tournament. Photo Credit: Contributed
WESTCHESTER COUNTY, N.Y. -- The local high school hockey season will kick off in style on Friday, Nov. 29 with eight Westchester County schools competing in the 2013 White Plains Thanksgiving Tournament at Ebersole Ice Rink.
The puck drops early this year as White Plains faces off at 7 a.m. against a team comprised of players from Sleepy Hollow, Irvington and Dobbs Ferry. Other area schools include The Eastchester/Tuckahoe/ Bronxville which plays at 9 a.m. on Friday. The Harvey School will face Stepinac at 11 a.m.
While the Katonah-based Harvey School plays a regular-season slate that consists mostly of Connecticut schools, head coach Tim Halewicz is looking to showcase his team's talent in a local setting.
"We aren't taking any team lightly. I am excited for the potential to see a variety of playing levels and styles at the beginning of the season," Halewicz said.
Here's the complete schedule:
9 a.m., Eastchester/Tuckahoe/Bronxville vs Monroe/Woodbury 11 a.m., The Harvey School vs Stepinac 1 p.m., Clarkstown vs Horace Greeley
Saturday, Nov. 30
8 a.m., Horace Greeley vs Eastchester/Tuckahoe/Bronxville 4 p.m., Monroe/Woodbury vs Clarkstown 6 p.m., White Plains vs Stepinac 8 p.m., Sleepy Hollow/Irvington/Dobbs Ferry vs The Harvey School
Sunday, Dec. 1
8 a.m., Eastchester/Tuckahoe/Bronxville vs Clarkstown 4 p.m., Stepinac vs Sleepy Hollow/Irvington/Dobbs Ferry 6 p.m., Horace Greeley vs Monroe/Woodbury 8 p.m., White Plains vs The Harvey School


text:
These treatments were applied to a porous Ti metal layer on a tot
These treatments were applied to a porous Ti metal layer on a total hip joint and the resultant joint has been in clinical use since 2007. It has been also demonstrated that the apatite formation on the treated Ti metal in the living body also occurred
in an acelullar simulated body fluid (SBF) with ion concentrations nearly equal to those of the human blood plasma, and hence bone-bonding ability of the treated Ti metal can be evaluated using SBF in vitro. However, it was recently found that certain selleck compound Ti metals subjected to the same NaOH and heat treatments display apatite formation in SBF which is decreased with the increasing volume of the NaOH solution used in some cases. This indicates that bone-bonding ability of the treated JQ1 supplier Ti metal varies with the volume of the NaOH solution used. In
the present study, this phenomenon was systematically investigated using commercial NaOH reagents and is considered in terms of the structure and composition of the surface layers of the treated Ti metals. It was found that a larger amount of the calcium contamination in the NaOH reagent is concentrated on the surface of the Ti metal during the NaOH treatment with an increasing volume of the NaOH solution, and that this inhibited apatite formation on the Ti metal in SBF by suppressing Na ion release from the sodium titanate into the surrounding fluid. Even a Ca contamination level of 0.0005 % of the NaOH reagent was sufficient to inhibit apatite formation. On the other hand, another NaOH reagent with a nominal purity of just 97 % did not exhibit any such inhibition, since it contained almost no Ca contamination. This indicates that NaOH reagent must be carefully selected for obtaining reliable bone-bonding implants of Ti metal
Epigenetics inhibitor by the NaOH and heat treatments."
"During T cell development in the thymus, a virgin repertoire of diverse TCR alpha beta recognition specificities in immature thymocytes is selected through positive and negative selection to form an immunocompetent and self-tolerant repertoire of mature T cells. Positive selection supports the survival of thymocytes that receive weak signals of low-avidity TCR engagement, whereas negative selection deletes potentially harmful self-reactive thymocytes upon high-avidity TCR engagement. Early studies have highlighted the role of TCR interaction with polymorphic MHC determinants in positive selection, while negative selection imposes TCR specificity to peptide antigens displayed by MHC molecules.
It also implicates the importance of axonal transport dysfunction
It also implicates the importance of axonal transport dysfunction in the process of neurodegeneration. These results may have relevance for understanding patho-physiological mechanisms involved in pseudotumor cerebri, syringomyelia, hydrocephalus and glaucoma diseases characterised by fluctuating pressure changes. (C) 2011 Elsevier B.V. All rights reserved."
"Aims/hypothesis Endoplasmic reticulum (ER) stress and the unfolded
protein response (UPR) can regulate insulin secretion, insulin action and in vitro hepatocyte glucose release. The aims of this study were to determine whether chemical agents that induce ER stress regulate glucose production in vivo and to identify a physiological setting in which this may be important.\n\nMethods A pancreatic clamp test was performed Caspase cleavage selleck in anaesthetised rats, and insulin and glucagon were replaced at basal levels. [6,6-(2)H(2)]Glucose was infused in the absence (CON, n=10) or presence of ER stress-inducing agents, namely, tunicamycin (Tun, n=10) or thapsigargin (Thap, n=10).\n\nResults Arterial insulin, glucagon, corticosterone and NEFA concentrations were constant throughout experiments and not different among groups. After 1 h, the
glucose concentration was significantly increased in Tun and Thap rats (1.5 +/- 0.2 and 2.1 +/- 0.3 mmol/l, respectively; mean +/- SD), but did not change in CON rats. Glucose production increased (p < 0.05) by 11.0 +/- 1.6 and 13.2 +/- 2.2 mu mol kg(-1) min(-1) in Tun and Thap rats, respectively, but did not change in CON rats. When glucose was infused in a fourth group (HYPER) to match the increase in glucose observed in the Tun and Thap rats, glucose production decreased by similar to 22 mu mol kg(-1) min(-1). Liver phosphorylase activity was increased and glycogen decreased 3-deazaneplanocin A manufacturer in the Tun and Thap groups
compared with the CON and HYPER groups. Given that glucose deprivation induces ER stress in cells, we hypothesised that hypoglycaemia, a condition that elicits increased glucose production, would activate the UPR in the liver. Three hour hyperinsulinaemic (5 mU kg(-1) min(-1)) -euglycaemic (EUG, similar to 7.2 mmol/l, n=6) or -hypoglycaemic (HYPO, similar to 2.8 mmol/l, n=6) clamps were performed in conscious rats. Several biochemical markers of the UPR were significantly increased in the liver, but not in kidney or pancreas, in HYPO vs EUG rats.\n\nConclusions/interpretation Based on our findings that the chemical induction of the UPR increased glucose production and that prolonged hypoglycaemia activated the UPR in the liver, we propose that the UPR in the liver may contribute to the regulation of glucose production during prolonged hypoglycaemia."
"The aim was to study the COX-1 inhibiting efficacy in context with hydroxyl radical scavenging properties of compounds bearing a carboxylic acid and ester function, respectively.
Patient outcome was recorded as healing of the ulcer and the pati
Patient outcome was recorded as healing of the ulcer and the patients were followed up
for 6 months or until the wound was healed. The percentage of malnutrition was 62.0% in the DFU patients. The SGA was closely correlated with infection (r=0.64), outcome (r=0.37) and BMI (r=-0.36), all P<0.001. The risk of poor outcome increased with malnutrition PKC412 [odds ratio (OR), 10.6, P<0.001]. The nutritional status of the DFU patients was independently correlated with the severity of infection and outcome (both P<0.001) and Wagner grades and nutritional status (SGA) were independent risk factors for patient outcome (both P<0.001). Nutritional status deteriorated as the severity of the DFU increased, and malnutrition was a predictor of poor prognosis."
"We present the analytical expression and computer implementation for the second-order energy derivatives of the
electronic excited state with respect to the nuclear coordinates in the time-dependent density functional theory (TDDFT) with Gaussian atomic orbital basis sets. Here, the Tamm-Dancoff approximation to the full TDDFT is adopted, and therefore the formulation process of TDDFT excited-state Hessian is similar to that of configuration interaction singles (CIS) Hessian. However, due to the replacement of the Hartree-Fock exchange integrals in CIS with the exchange-correlation kernels in TDDFT, many quantitative changes in the derived equations Tariquidar cost are arisen. The replacement also causes additional technical difficulties associated with SB273005 cell line the calculation
of a large number of multiple-order functional derivatives with respect to the density variables and the nuclear coordinates. Numerical tests on a set of test molecules are performed. The simulated excited-state vibrational frequencies by the analytical Hessian approach are compared with those computed by CIS and the finite-difference method. It is found that the analytical Hessian method is superior to the finite-difference method in terms of the computational accuracy and efficiency. The numerical differentiation can be difficult due to root flipping for excited states that are close in energy. TDDFT yields more exact excited-state vibrational frequencies than CIS, which usually overestimates the values. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3605504]"
"Background and Objectives\n\nThe aim of the study was to evaluate, in an international collaboration, three lyophilized intravenous immunoglobulin (IVIG) preparations for their suitability to standardize and control haemagglutination testing for anti-A and anti-B in IVIG products.\n\nMaterials and Methods\n\nTwenty-three laboratories tested candidate IVIG reference reagents consisting of a Positive control (07/306), a Negative control (07/308), and a specifically formulated Limit preparation (07/310) to define the maximum (e.g.
Methods: In total, 32 eyes from 16 rabbits were divided into
\n\nMethods: In total, 32 eyes from 16 rabbits were divided into 4 groups. CX-6258 chemical structure Group 1 was treated with intact epithelium and without BAC. In groups 2 and 3, the epithelium was left intact and a hypoosmolar solution of riboflavin that contained
BAC 0.02% or 0.04% was used. Group 4 was treated according to the standard protocol with mechanical debridement of the epithelium. After the treatment of both eyes, the rabbits were euthanized to prepare the corneas in order for the determination of the riboflavin absorption coefficient and biomechanical properties.\n\nResults: The absorption coefficients of groups 2, 3, and 4 were significantly increased compared to group 1. There were no significant differences between groups 2, 3, and 4. Stress-strain values and Young's modulus for groups 2, 3, and 4 were significantly increased compared to group 1. The stiffening effects did not differ within groups 2, 3, and 4. The resistance to enzymatic digestion
was significantly increased in groups 2, 3, and 4 as compared to group 1.\n\nConclusions: Treatment with BAC 0.02% induces sufficient epithelial permeability for the passage of riboflavin, which enables its stromal diffusion and results in increased corneal stiffening Volasertib mouse after cross-linking as compared to the standard protocol. Further safety studies will be required before clinical use."
"Sickle hemoglobin forms long, multistranded polymers that account for the pathophysiology of the disease. The molecules in these polymers make significant contacts along the polymer axis (i.e., axial contacts) as well as making diagonally directed contacts (i.e., lateral contacts). The axial contacts do not engage the mutant beta 6 Val and its nonmutant receptor region on an adjacent molecule, in contrast to the lateral contacts which do involve the mutation site. We have studied the association
process by elastic light scattering measurements as a function of temperature, concentration, and primary and quaternary structure, employing an instrument selleck of our own construction. Even well below the solubility for polymer formation, we find a difference between the association behavior of deoxy sickle hemoglobin molecules (HbS), which can polymerize at higher concentration, in comparison to COHbS, COHbA, or deoxygenated Hemoglobin A (HbA), none of which have the capacity to form polymers. The nonpolymerizable species are all quite similar to one another, and show much less association than deoxy HbS. We conclude that axial contacts are significantly weaker than the lateral ones. All the associations are entropically favored, and enthalpically disfavored, typical of hydrophobic interactions. For nonpolymerizable Hemoglobin, Delta H-o was 35 +/- 4 kcal/mol, and Delta S was 102.7 +/- 0.5 cal/(mol-K). For deoxyHbS, Delta H-o was 19 +/- 2 kcal/mol, and Delta S was 56.9 +/- 0.5 cal/(mol-K).
2 mm), while 4 exhibited significant decompression based shift (m
2 mm), while 4 exhibited significant decompression based shift (mean: 4.7 mm), and 3 showed significant shear displacement along the surface of the brain (mean: 7.1 mm).\n\nDiscussion: Shift in electrode position with respect to the cortical surface has never been
precisely measured. We show that in 50% of our cases statistically significant shift occurred. These observations demonstrate the potential utility of complimenting electrode position measures at the reopening of the craniotomy with 3D electrode and brain surface models derived from post-implantation CT and MR imaging for better definition of surgical boundaries. (C) 2011 Elsevier B.V. All rights reserved."
"RNA processing and degradation is initiated by endonucleolytic cleavage of the target RNAs. In many bacteria, this activity is performed by RNase E which is not present in Bacillus subtilis and other Gram-positive bacteria. Recently, the essential endoribonuclease RNase Y has Milciclib been discovered in B. subtilis. This RNase is involved in the degradation of bulk mRNA suggesting a major role in RNA metabolism. However, only a few targets of RNase Y have been identified so far. In order to assess the global impact of RNase Y, we compared the transcriptomes in response to the expression level of RNase Y. Our results demonstrate that processing by RNase Y results in accumulation of about 550
mRNAs. Some of these targets were substantially stabilized by RNase Y depletion, resulting in half-lives in the range of an hour. Moreover, about 350 mRNAs were less abundant 3-deazaneplanocin A when RNase Y was depleted among them the mRNAs of the operons required for biofilm formation. Interestingly, overexpression selleck inhibitor of RNase Y was sufficient to induce biofilm formation. The results presented in this work emphasize the importance of RNase Y as the global acting endoribonuclease for B. subtilis."
"Introduction: In Australia, post-marketing surveillance for intussusception following vaccination commenced with funding of RotaTeq (R) and Rotarix (R) vaccines under the National Immunization Program (NIP) in July 2007.\n\nMethods: Two
active surveillance mechanisms (hospital-based case ascertainment and monthly reports from paediatricians) identified intussusception cases between 1st July 2007 and 31st December 2008 in four states. Linkage to vaccination records identified cases occurring within 1-7 and 1-21 days of rotavirus vaccination. Expected cases within the post-vaccination windows were calculated by applying rates of intussusception from national hospitalisation data over 6 years (mid-2000 to mid-2006), by age and state, to numbers vaccinated (by dose) according to the Australian Childhood Immunization Register.\n\nResults: Combining exposure windows associated with all doses of rotavirus vaccine from 1 to 9 months of age, there was no evidence of an increased risk of intussusception following vaccination for either vaccine.
This is because in calculating the GI, individual glycemic respon
This is because in calculating the GI, individual glycemic responses to
glucose are normalized to 100. GI values are, therefore, relative and are not necessarily a reliable guide to the person's actual individual AUC when consuming a food. Without knowledge of the person's characteristic blood glucose responses, reliance only on the GI may be misleading. (C) 2010 IUBMB IUBMB Life, 62(8): 637-641, 2010″
"The degradation behavior against a surge-current in the ZPCCYE (ZnO-Pr6O11-CoO-Cr2O3-Y2O3-Er2O3) varistors was investigated for different amounts of Er2O3. The addition of Er2O3 has a significant effect on nonlinear electrical properties and surge degradation behavior of the BIIB057 cost ZPCCYE varistors. Increasing amount of Er2O3 improved the clamp characteristics, in which the clamping
voltage (K) decreases at a surge-current of 1-40 A. The varistors added with 0.5 mol% Er2O3 exhibited the strongest electrical Rigosertib chemical structure stability, with the variation rate of the breakdown field of -3.2%, the variation rate of the nonlinear coefficient of -20.9%, and the variation rate of the leakage current of -40.0% after applying 1000 times for a surge-current of 100 A/cm(2). Furthermore, the varistors added with 0.5 mol% Er2O3 exhibited the good surge withstand capability with the variation rate of the breakdown field of -7.9% after applying the surge-current of 400 A. On the contrary, the varistors added with 0.25 mol% were destroyed after applying the surge-current of 400 A and the varistors added with 1.0 mol% were destroyed after applying 55 times for a surge-current of 100 A/cm(2). (C) 2012 Elsevier Ltd and Techna Group S.r.l. All rights reserved."
"Hypertonie betrifft in der westlichen Welt einen betrachtlichen Teil der Bevolkerung, effektive Therapien stehen zur Verfugung. Trotzdem ist der Blutdruck in den USA z.B. bei weniger als der Halfte der Patienten ausreichend kontrolliert. Deshalb hat eine gemeinnutzige Stiftung in den USA ein bevolkerungsbasiertes strukturiertes Programm selleck products zur besseren Blutdruckeinstellung initiiert, dessen Ergebnisse Jaffe et al. hier vorstellen. JAMA
2013; 310: 699-705″
"The classic single-phase Newtonian blood flow model ignores the motion of red blood cells (RBCs) and their interaction with plasma. To address these issues, we adopted a multiphase non-Newtonian model to carry out a comparative study between a helical artery bypass graft (ABG) and a conventional ABG in which the blood flow is composed of plasma and RBCs. The investigation focused on the mechanism of RBC buildup in an ABG but the haemodynamic parameters obtained by single-phase and multiphase models were also compared. The aggregation of RBCs along the inside wall of a conventional ABG and at the heel of its distal anastomosis was predicted while a poor aggregation was observed along the helical ABG. In addition, RBCs were observed to gradually sediment along the gravity direction.
Perceptions of the provision of neighbourhood amenities
seems to be more strongly associated with women's than men's smoking status, whereas the perceived quality of the local neighbourhood appears to be a better predictor of men's smoking.\n\nConclusions: Efforts to reduce smoking levels among more deprived groups may need to pay more attention to the role of local environmental conditions in influencing smoking behaviour."
"In check details recent literature, very few studies have reported the use of the combination of indicators from ecological communities and ecotoxicity biomarkers in field experiments to assess agricultural quality. Therefore, the aim of this study was to determine the influence of three soil management practices of vine inter-rows (chemical weeding, mechanical weeding and grass-covering) on earthworms,
in the PND-1186 datasheet Gaillac vineyard (South-West France). The sampling, identification and counts of earthworms were performed in spring and autumn over three years in order to determine the influence of the management practices. Focussing on the most abundant species, Aporrectodea nocturna, biomarker assays (glutathione-S-transferase (GST), catalase (CAT) and cholinesterase (ChE) activities) were conducted to check physiological disturbances that are indirectly linked to soil management practices.\n\nA strong influence of soil management practices was highlighted on earthworm ecology and physiology in the vine inter-rows. Chemical
weeding favoured worm proliferation, but proportionally decreased the number of epi-anecic species. Mechanical weeding dramatically decreased the total number of earthworms, both adults and juveniles, and their biomass. Under these soil farming practices, variations of metabolisation and anti-oxidant enzyme activities were observed, suggesting an increase in pesticide bioavailability. Grass-covering seemed to be the best practice, at least from an environmental point of view. Neurotoxicity enzyme (cholinesterase) activity in vineyard earthworms was not affected by pollutants conventionally sprayed on the vineyard, regardless of soil agricultural practice.\n\nIt was concluded that soil management practices can both modify earthworm communities and physiology, Acalabrutinib price inducing variations of the following factors: protection against predators, environmental conditions and availability of pesticide and nutrients. (C) 2012 Elsevier Masson SAS. All rights reserved."
"In antioxidant activity testing, it has been argued that assays capable of measuring the inhibitive action against the biologically relevant peroxyl radicals (ROO center dot) from a controllable source are preferable in terms of simulating physiological conditions because ROO center dot is the predominant free radical found in lipid oxidation in foods and biological systems.
Genomic systematic evolution of ligands by exponential enrichment
Genomic systematic evolution of ligands by exponential enrichment and electrophoretic mobility shift assays revealed that SCO7518 specifically binds to an operator sequence located upstream of the sco7519 gene, which encodes a maltose O-acetyltransferase. These results suggest that SCO7518 is a transcriptional repressor of sco7519 expression. (C) 2014 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved."
"Retroelements are an abundant class of noncoding DNAs present in about half of the human genome. Among them, L1,
Alu and SVA are currently active. They "jump" by retrotransposition, shuffle genomic regions by 5′ and 3′ transduction, and promote or inhibit gene transcription by providing alternative promoters or generating antisense PKC412 and/or
regulatory noncoding RNAs. Recent data also suggest that retroelement insertions into exons and introns of genes induce different types of genetic disease, including cancer. Retroelements interfere with the expression of genes by inducing alternative splicing via exon skipping and exonization using cryptic splice sites, and by providing polyadenylation signals. Here we summarize our current understanding of the molecular mechanisms of retroelement-induced mutagenesis which causes fifty different types of human disease. We categorize these mutagenic effects according to eleven different mechanisms and show that most of them may be explained either by traditional exon definition or transcriptional Tariquidar molecular weight interference, a previously unrecognized molecular mechanism. In summary, this review gives an overview of retroelement
insertions in genes that cause significant changes in their transcription and cotranscriptional splicing and show a remarkable level of complexity. (c) 2013 Elsevier B.V. All rights reserved."
"The DNA-binding transcriptional activator Gal4 and its regulators Gal80 and Gal3 constitute a galactose-responsive switch for the GAL genes of Saccharomyces cerevisiae. Gal4 binds to GAL gene UAS(GAL) (upstream activation sequence in GAL gene promoter) sites as a dimer via its N-terminal domain and activates transcription via a C-terminal transcription activation SB273005 domain (AD). In the absence of galactose, a Gal80 dimer binds to a dimer of Gal4, masking the Gal4AD. Galactose triggers Gal3-Gal80 interaction to rapidly initiate Gal4-mediated transcription activation. Just how Gal3 alters Gal80 to relieve Gal80 inhibition of Gal4 has been unknown, but previous analyses of Gal80 mutants suggested a possible competition between Gal3-Gal80 and Gal80 self-association interactions. Here we assayed Gal80-Gal80 interactions and tested for effects of Gal3. Immunoprecipitation, cross-linking, and denaturing and native PAGE analyses of Gal80 in vitro and fluorescence imaging of Gal80 in live cells show that Gal3-Gal80 interaction occurs concomitantly with a decrease in Gal80 multimers.
The lower proliferative response and IL-2 production capacity of
The lower proliferative response and IL-2 production capacity of cancer patients
PBLs in comparison with that of the control group cells were the functional consequences of reported in this study signaling abnormalities."
"It is believed that the bitter taste of paracetamol, this website a pain killer drug, is due to its hydroxyl group. Hence, it is expected that blocking the hydroxy group with a suitable linker could inhibit the interaction of paracetamol with its bitter taste receptor/s and hence masking its bitterness. Using DFT theoretical calculations we calculated proton transfers in ten different Kirby's enzyme models, 1-10. The calculation results revealed that the reaction rate is linearly correlated with the distance between the two reactive centers (r(GM)) and the angle of the hydrogen bonding (alpha) formed along the reaction pathway. Based on these results three novel tasteless paracetamol prodrugs were designed and the thermodynamic and kinetic parameters
for their proton transfers were calculated. Based on the experimental Rigosertib inhibitor t(1/2) (the time needed for the conversion of 50% of the reactants to products) and EM (effective molarity) values for processes 1-10 we have calculated the t(1/2) values for the conversion of the three prodrugs to the parental drug, paracetamol. The calculated t(1/2) values for ProD 1-3 were found to be 21.3 hours, 4.7 hours and 8 minutes, respectively. Thus, the rate by which the paracetamol prodrug undergoes cleavage to release paracetamol can be determined according to the nature of the linker of the prodrug (Kirby's enzyme model 1-10). Further, blocking the phenolic hydroxyl group by
a linker moiety is believed to hinder the paracetamol bitterness."
"Cell cycle regulation by differentiation signals is critical for eukaryote development. We investigated the roles of bone morphogenetic protein (BMP)-4, an important stimulator of osteoblast differentiation and bone formation, in regulating cell cycle learn more distribution in four osteoblast-like cell lines and mouse primary osteoblasts, and the underlying mechanisms. In all cells used, BMP-4 induced G(0)/G(1) arrest. The molecular basis of the BMP-4 effect was analyzed, and the presentation on molecular mechanism is focused on human MG63 cells. BMP-4 induced p21(CIP1) and p27(KIP1) expressions and hence cell differentiation but had no effects on the expressions of cyclins A, B1, D1, and E, cyclin-dependent protein kinase-2, -4, and -6. Using specific small interfering RNA (siRNA), we found that BMP-4-induced G(0)/G(1) arrest, and p21(CIP1) and p27(KIP1) expressions were mediated by BMP receptor type IA (BMPRIA)-specific Sma- and Mad-related protein (Smad)1/5.
"Several carbon-black filled
styrene-butadiene rub
styrene-butadiene rubbers are subjected to monotonic uniaxial tension tests in order to investigate the effects of the amount of fillers and of the crosslink density on their mechanical properties. The Young modulus, the volume changes associated with material damage and the stretch to failure are extracted and discussed. Results compare well to the literature results when exist and quantitative analysis are proposed when possible. Results show that filled rubbers are not incompressible when submitted to uniaxial tension tests and their volume changes selleck chemicals llc are strongly dependent of the amount of fillers but are unaffected by the crosslink density. The latter shows strong impact on the filled rubbers stretch to failure but more interestingly this impact is comparable to what is encountered in unfilled rubbers. The stretch to failure is improved by the addition of fillers with an optimum for material filled around 30 phr. (c) 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013″
"Animals frequently switch from one behavior to another, often to meet the demands of their changing environment or internal state. What factors Screening Library control these behavioral switches
and the selection of what to do or what not to do? To address these issues, we will focus on the locomotor behaviors of two distantly related "worms," check details the medicinal leech Hirudo verbana (clade Lophotrochozoa) and the nematode Caenorhabditis elegans (clade Ecdysozoa). Although the neural architecture and body morphology of these organisms are quite distinct, they appear to switch between different forms of locomotion by using similar strategies of decision-making. For example, information that distinguishes between liquid and more solid environments dictates whether an animal swims or crawls. In the leech, dopamine
biases locomotor neural networks so that crawling is turned on and swimming is turned off. In C. elegans, dopamine may also promote crawling, a form of locomotion that has gained new attention."
"A new fluorescent nanoparticle was synthesized by chemical crosslinking of polyacrylic acid using 4-aminoethanol-N-hydroxyethanyl-1,8-naphthalimide as the crosslinker. The particle possesses excellent characteristics, including low cytotoxicity, water solubility and good fluorescence properties. The interaction of the particle with bovine serum albumin was investigated by absorbance, fluorescence and circular dichroism spectroscopic methods. The interaction mechanisms, binding model and reciprocal effects on structure and fluorescence between nanoparticle and protein are discussed. The spectral data indicated that the nanoparticle could spontaneously form a reversible complex with bovine serum albumin in solution used mainly by hydrogen bonds and van der Waals forces.

redpajama_set_name: RedPajamaCommonCrawl


Gavin Conroy has had a longstanding interest in aviation, first gaining his pilot's licence at the age of 16. He moved seriously into aviation photography in 2005, and since then has spent hundreds of hours planning and flying to put together the collection of photographs that formed the basis of Precious Metal: Classic Fighters in New Zealand. When not taking photographs he works in the timber industry and is based in Blenheim.


text:
Medical Symptoms
Med. Tests & Exams
Surgery & Procedures
Injuries & Wounds
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You are here : 3-RX.com > Home > Infections
Lack of health insurance limits hepatitis C patients' access to latest antiviral therapy
• Infections • • Public Health • Feb 25 11
New research has determined that patients in the U.S. with hepatitis C virus (HCV) are twice as likely to not have health insurance coverage compared with those without the disease. In fact researchers found only a third of HCV infected Americans have access to antiviral therapy; the remaining are either uninsured or not candidates for therapy due to treatment contraindications. Details of this study are published in the March issue of Hepatology, a peer-reviewed journal of the American Association for the Study of Liver Diseases (AASLD).
HCV is the most common cause of chronic liver disease, hepatocellular (liver) cancer, and liver transplantation in the U.S., with up to 85% of HCV-positive individuals (3.5 million) developing chronic HCV infection. Symptoms of chronic HCV are non-specific which can inhibit diagnosis and as many as 75% of patients are unaware of their HCV infection (Hagan et al., 2006). Furthermore, the Centers for Disease Control and Prevention (CDC) estimates that HCV causes 12,000 deaths in the U.S. each year.
"Successful treatment with antiviral therapy improves health-related quality of life in patients with HCV and could potentially reduce morbidity and mortality in patients," said Zobair Younossi, MD, MPH, from the Center of Liver Diseases at Inova Fairfax Hospital in Virginia and lead author of the study. "A significant number of HCV patients, however, may not even have access to antiviral therapy due to lack of adequate health insurance coverage." It is estimated to cost up to $48,000 per year for monitoring and treatment of HCV.
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Can breastfeeding transmit yellow fever after maternal vaccination?
• Children's Health • • Infections • Feb 07 11
A five-week old infant most likely contracted a vaccine strain of yellow fever virus through breastfeeding, according to a case report published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only)
"Until recently, avoidance of vaccination of breastfeeding women with yellow fever vaccine had been based on theoretical grounds only," writes Dr. Susan Kuhn, with coauthors. "We report the probable transmission of vaccine strain of yellow fever virus from a mother to her infant through breastfeeding," which supports current recommendations for breastfeeding mothers to avoid the vaccine.
The yellow fever vaccine is a live-virus vaccine that has been used since the 1940s.
New research examines how HIV infections occur on the molecular level
• AIDS/HIV • • Infections • Jan 18 11
The UK's National Physical Laboratory (NPL) with the University of Edinburgh and IBM's TJ Watson Research Center have published new research about the structure of an HIV-1 protein that could help to develop new drugs to stop the virus infecting healthy cells.
The research provides a new insight into how the changes in structure of a small part of an HIV protein (a membrane proximal peptide) may alter the infection of the virus into healthy cells. The team was able to observe key changes in this part of the protein implicated in the early stages of the infection by using a combination of powerful experimental and computational tools. This is the first attempt to demonstrate that the inducible binding of the peptide with membrane-like surfaces can serve as a responsive molecular anchor underpinning HIV fusion to target cells.
This information is important as it gives us a better understanding of how HIV infections take hold at the molecular level. Drug designers could use this information to develop treatments that stop HIV from entering a healthy cell and infecting it.
Researchers visualize herpes virus' tactical maneuver
• Infections • • Sexual Health • Jan 07 11
For the first time, researchers have developed a 3D picture of a herpes virus protein interacting with a key part of the human cellular machinery, enhancing our understanding of how it hijacks human cells to spread infection and opening up new possibilities for stepping in to prevent or treat infection. This discovery uncovers one of the many tactical manoeuvres employed by the virus.
The Biotechnology and Biological Sciences Research Council (BBSRC)-funded team, led by The University of Manchester, have used NMR - a technique related to the one used in MRI body scanners and capable of visualising molecules at the smallest scales – to produce images of a herpes virus protein interacting with a mouse cellular protein. These images were then used to develop a 3D model of this herpes virus protein interacting with human protein. The research is published this evening (06 January) in PLoS Pathogens.
Lead researcher Dr Alexander Golovanov from Manchester's Interdisciplinary Biocentre and Faculty of Life Sciences said "There are quite a few types of herpes viruses that cause problems as mild as cold sores through to some quite serious illnesses, such as shingles or even cancer. Viruses cannot survive or replicate on their own – they need the resources and apparatus within a human cell to do so. To prevent or treat diseases caused by viruses we need to know as much as possible about how they do this so that we can spot weak points or take out key tactical manoeuvres."
Hepatitis C: In 2011, a predictive marker for response to therapy
• Infections • Jan 05 11
Scientists at Inserm and Institut Pasteur have performed biomarker discovery on patients being treated for chronic hepatitis C infection. Their work, published in The Journal of Clinical Investigation, demonstrates that the plasma levels of the protein IP-10 predict, prior to treatment initiation, the efficacy of treatment with pegylated-interferon and ribavirin. Based on these results, the scientists have developed a prognostic test. Commercialization is anticipated in 2011, and will help inform physicians of the chances that patients will respond to standard treatment or if instead they will require new therapeutic cocktails (e.g., inclusion of protease inhibitors).
Importantly, hepatitis C is the leading cause of primary liver cancer (hepatocellular carcinoma) and it remains an important cause of liver failure due to fibrosis and cirrhosis. This infectious disease represents a major public health problem, with greater than 170 million cases worldwide. The World Health Organization estimates 3 to 4 million new cases per year and considers the virus a " viral time bomb" due to the long term sequella of infection.
Currently, there is no approved vaccine available and approximately 80% of individuals infected by the virus develop chronic disease, a risk factor for cirrhosis, liver failure, liver cancer as well as other medical complications (e.g., diabetes).
New test announced for major killer of lung transplant patients
• Infections • • Respiratory Problems • Jan 01 11
A lung transplant can mean a new chance at life. But many who receive one develop a debilitating, fatal condition that causes scar tissue to build up in the lungs and chokes off the ability to breathe.
University of Michigan researchers hope a new diagnostic tool they developed to predict bronchiolitis obliterans syndrome (BOS) will allow doctors to intervene earlier and, ultimately, to provide life-saving treatments.
BOS is the leading cause of death for those who survive one year after lung transplantation and more than half of recipients will develop BOS within five years. There is currently no cure.
New Research Finds Delaying Surgical Procedures Increases Infection Risk and Health Care Cost
• Infections • • Surgery • Dec 15 10
Delaying elective surgical procedures after a patient has been admitted to the hospital significantly increases the risk of infectious complications and raises hospital costs, according to the results of a new study in the December issue of the Journal of the American College of Surgeons.
The occurrence of infection following surgical procedures continues to be a major source of morbidity and expense despite extensive prevention efforts that have been implemented through educational programs, clinical guidelines, and hospital-based policies. The authors of the study queried a nationwide sample of 163,006 patients, 40 years of age and older, from 2003 to 2007. They evaluated patients who developed postoperative complications following one of three high-volume elective surgical procedures: 87,318 coronary artery bypass graft (CABG) procedures, 46,728 colon resections, and 28,960 lung resections.
The infectious complications evaluated included pneumonia, urinary tract infections, postoperative sepsis and surgical site infections.
Cholera fighting efforts restart in Haiti's north
• Infections • • Public Health • Nov 22 10
Aid supplies to combat Haiti's deadly cholera epidemic are flowing again into the country's northern regions after protests by Haitians blaming U.N. troops for the outbreak, humanitarian groups said on Sunday.
Vehicles carrying equipment from some aid groups have begun to reach the northern city of Cap-Haitien, where aid efforts were disrupted last week by several days of protests that saw Haitians throw up road barricades and hurl stones at U.N. peacekeepers, said Imogen Wall of the U.N. humanitarian agency, OCHA.
"The security situation there has now stabilized," Wall said. "We're going to have to scramble to get back to where we were."
Studies examine costs, prospects of ending malaria
• Infections • Oct 30 10
Eliminating malaria can be achieved only with repeated investment over the long term and will require a major shift in policy and funding now focused on control of the disease, experts said on Friday.
In a series of studies in the Lancet medical journal about the prospect of trying to eradicate the often deadly infectious disease, scientists said that for many countries, wiping it out would take many decades rather than be a quick victory.
Like routine immunizations against diseases such as smallpox or measles, it would require long-term investment to make sure the disease does not come back, even after the intensive elimination activity is over, they said.
Oklahoma investigates salmonella outbreak
• Infections • • Public Health • Oct 05 10
Oklahoma health officials are investigating an outbreak of salmonella in several schoolchildren and some adults and say it may be connected to similar outbreaks in Iowa and Nebraska.
A total of 16 cases in three counties have been identified involving at least four elementary schools, according to Leslea Bennett-Webb, spokeswoman for the Oklahoma Department of Health.
No one has died, although one adult has been hospitalized due to the strain of Salmonella "Java" that can cause bloody diarrhea, abdominal cramps, fever and vomiting.
Genetic signature may lead to better TB diagnosis
• Infections • • Tuberculosis • Aug 19 10
Scientists have found a "genetic signature" in the blood of patients with active tuberculosis (TB) and believe their discovery could help develop better diagnostic tests for the disease, as well as better treatments.
More than 2 billion people, or a third of the world's population, are estimated to be infected with the organism Mycobacterium tuberculosis (MTB), which causes TB, but the vast majority have the infection in latent form and have no symptoms.
The British scientists said they had now found a pattern of genes in the blood that is specific to up to 10 percent of those 2 billion people who develop active TB in their lungs.
Dogs may help collar Chagas disease
• Infections • • Public Health • Jul 12 10
Chagas disease, for example, is caused by a parasite that roams with only limited control among the rural poor in Latin America. The main vector for the parasite Trypanosoma cruzi is the triatomine insect, or "kissing bug," which thrives in the nooks and crannies of mud-brick dwellings. The bug sucks the blood of mammals, helping T. cruzi move between wildlife, cats, dogs and humans.
"Dogs tend to lie on porches or other areas easily accessible to the bugs," says disease ecologist Uriel Kitron, chair of environmental studies at Emory University. "And when a dog is malnourished and its immune system isn't great, they are even more at risk."
Kitron has been researching Chagas disease in remote communities of northern Argentina for the past 10 years. "One of our most significant findings is the importance of dogs in both the spread of the disease, and the potential to help control it," he says, explaining that dogs can make good sentinels for health officials monitoring T. cruzi transmission.
Early-Life Exposure to Polychlorinated Biphenyls Reduces Immune Response to Vaccination
• Immunology • • Infections • Jun 21 10
Children exposed to polychlorinated biphenyls (PCBs) early in life later had a diminished immune response to diphtheria and tetanus vaccinations, according to a study published online June 20 ahead of print in the peer-reviewed journal Environmental Health Perspectives (EHP). This result suggests that PCB exposure during the first years of life, a critical period in immune system development, could undermine the effectiveness of childhood vaccinations and possibly impair immune system responses to infection.
PCBs are long-lived environmental contaminants that are suspected to be toxic to the immune system. The study included 587 children born between 1999 and 2001 who lived in the Faroe Islands. The residents of the Faroe Islands, which lie midway between Norway and Iceland in the North Atlantic, have widely varying PCB exposure due to differing consumption patterns of contaminated traditional foods such as pilot whale blubber. Routine childhood vaccinations, which feature standard antigen doses at set time points, provided an opportunity to examine immune responses in the Faroese children.
Mothers provided blood samples at 32 weeks of pregnancy and milk samples 4 to 5 days after birth.
Russia registers first polio death in a decade
• Infections • • Public Health • Jun 14 10
Russia has confirmed its first death from polio in more than a decade, the country's top public health official said on Sunday, Interfax news agency reported.
A citizen of the former-Soviet Central Asian country of Uzbekistan died of polio in the Urals Mountains city of Yekaterinburg in early June, Gennady Onishchenko was quoted as saying. "Tests have confirmed this," he said.
Onishchenko's spokeswoman was unavailable to comment on the report on Sunday.
African mining may be driving TB epidemic: study
• Infections • • Tuberculosis • Jun 02 10
Poor living and working conditions for miners of gold, diamonds and other precious metals have contributed significantly to tuberculosis (TB) epidemics across Africa, scientists said on Tuesday.
Researchers from Britain and the United States said their study suggested that crowded living and working conditions, dust in mines, and the spread of HIV mean Africa's mining industry may figure in up to 760,000 new cases of TB each year.
Men travelling from afar to work in mines, such as from Botswana to South Africa, are at the greatest risk of getting TB, the researchers wrote in a study published in the American Journal of Public Health.
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Q: How Can I Remove Drastic Brightness Variations In A Video? I have a stream of images that I'm getting from a video camera. I've found that sometimes an image from the stream will have a large spike in brightness (every pixel jumps or drops in value), and then return to its normal brightness level in the next image.
This is a huge problem for my algorithms. Is there anyway I can prevent this spike in brightness? I was thinking of something like a low pass filter on each pixel, but I was wondering if anyone has more experience with this issue.
I will be designing in MATLAB and implementing in OpenCV. If either platform has some nifty functions I'd love to hear about them.
Thanks for your time!

A: A fairly naive solution is to convert your images into YUV color space, perform histogram equalization on the Y channel, and then convert back to RGB. This method attempts to normalize the luminance of the image to the same distribution for every frame, compensating for variations in brightness.
The code to do this in OpenCV is:
cv::cvtColor(img, img, CV_BGR2YUV);
std::vector<cv::Mat> channels;
cv::split(img, channels);
cv::equalizeHist(channels[0], channels[0]);
cv::merge(channels, img);
cv::cvtColor(img, img, CV_YUV2BGR);

This produces an effect shown below. Note that the brightness of the two images in the Equalized column is more similar than that of the two original images. Your mileage will vary.

A: Every pixel? Sounds like a lighting or camera problem. If you can't control for either, I'd just detect the bad frames and drop/ignore them. They are likely trouble anyway, since you may have areas that are saturated or clipped.
For detection I'd just start by looking at the low percentiles of the histogram in separate regions in the image, and looks for frames where they all jump up or down

redpajama_set_name: RedPajamaStackExchange


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La batalla de Cannes o Cannas fou un enfrontament militar entre romans i cartaginesos prop de la ciutat de Cannes (del llatí Cannae, que vol dir 'canyes') a la Pulla i forma part de la Segona Guerra Púnica.

Antecedents
Anníbal havia passat l'hivern a Gerunium i en va sortir al començar la primavera del 216 aC en direcció a Cannes, que era una ciutat que havia quedat destruïda l'any anterior però de la que la ciutadella es conservava i els romans l'estaven utilitzant; els cartaginesos es van apoderar del lloc i de les provisions i subministraments romans emmagatzemats allí. Va ocupar la ciutadella i va establir el camp a la rodalia. Els generals romans van rebre ordre de buscar un enfrontament general i van seguir al cartaginès quedant ambdues forces no gaire lluny; l'endemà Varró va insistir a avançar encara més a prop i els romans van establir dos camps: un a prop del costat sud del riu Vergellus (on ja eren abans) i un altre amb poques forces al costat oposat (el riu era fàcil de creuar).

El dia de la batalla, Varró va travessar el riu amb la part més important del seu exèrcit. El van organitzar en dos blocs en línies tancades, el d'infanteria lleugera davant i el de la pesant darrere; a la dreta, a tocar del riu, la cavalleria romana, i a l'esquerra la cavalleria dels aliats.

Anníbal va formar també amb dues línies pel centre, formades per gals i ibers, apuntant al centre romà; els dos flancs els cobrien els soldats d'infanteria libis, a la dreta la cavalleria númida i a l'esquerra la cavalleria ibera i dels gals.

Desenvolupament tàctic
Els romans van iniciar l'atac i el centre cartaginès va cedir el terreny, però les ales cartagineses es van mantenir fermes. En aquesta posició van iniciar l'atac les cavalleries cartagineses; la númida va trobar resistència dels aliats romans, però la cavalleria íbera i gal·la va ser superior als seus rivals. Anníbal va enviar la resta d'aquesta cavalleria a reforçar a la númida.

Les dues ales d'infanteria cartaginesa no podien ser enfonsades per les ales romanes, que finalment foren rebutjades cap al centre on els romans portaven avantatge però havien avançat tant que es va acabar per formar una u en la que els romans van quedar envoltats pels cartaginesos. La cavalleria cartaginesa que va reforçar als númides va rebutjar la cavalleria dels aliats romans i llavors va començar el moviment sobre l'esquena de la infanteria romana. La cavalleria romana va retirar-se i les dues ales de la cavalleria cartaginesa van tenir el camp lliure per situar-se a l'esquena de l'infantaria romana i tancar el setge. La resta de la batalla fou l'eliminació de l'exèrcit romà. Uns cinquanta mil romans (setze legions) van morir a la batalla.

Conseqüències
Lluci Banci (Lucius Bantius) un militar romà natural de Nola servia a l'exèrcit romà a la batalla, on fou greument ferit i fet presoner per Anníbal. Aquest el va tractar amablement i el va enviar a casa seva, i en agraïment Banci va voler rendir la ciutat de Nola als cartaginesos, però finalment va tornar a la lleialtat als romans mercès a la prudent conducta de Marcel.

Notes

Referències

Bibliografia

Vegeu també
 Pacuvi Calavi
 Batalla de Cerignola

Enllaços externs

 http://www.roman-empire.net/army/cannae.html
 http://cgsc.leavenworth.army.mil/carl/resources/csi/Cannae/cannae.asp#cannae

Pulla
Cannes
Cannes
Cannes
Història militar dels antics celtes

redpajama_set_name: RedPajamaWikipedia


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Historic MoU Signed with UNICEF India
India's Global Interfaith WASH Alliance (GIWA) signed a historic Memorandum of Understanding (MoU) today between the Representative of UNICEF in India, Louis-Georges Arsenault and H.H. Pujya Swami Chidanand Saraswati, Co-Founder of the Global Interfaith WASH Alliance and President of Parmarth Niketan, Rishikesh, one of India's largest interfaith organizations.
The agreement signed today at UNICEF Country Office in New Delhi, follows the launch of GIWA on 25th September 2013, at UNICEF Headquarters in New York, under sponsorship of USAID and the Government of the Netherlands.
At the signing ceremony, H.H. Pujya Swami Chidanand Saraswatiji called for an increased focus on improving the situation of Water, Sanitation and Hygiene in India.
"We have worshipped the creator for long, now it is time we take care of His creations, so that life may be improved for all" said the spiritual leader, while adding that changing mindsets is crucial to address the sanitation crisis in India.
Pujya Swamiji highlighted the role of children as active agents of change. "Children are the ones who can really make the difference. They can change the views of their families and, thus, help to bring about a positive change," he stated.
"Working together – in a strong partnership, we will drive positive change" pointed out Louis-Georges Arsenault, Representative of UNICEF in India.
GIWA and UNICEF aim to engage different faiths as allies in the efforts to create a world where every human being has access to safe drinking water, improved sanitation and proper hygiene.
As a first step, GIWA India with technical support from UNICEF, plans a 'Worship to WASH' summit in Rishikesh, Uttarakhand later this year. The Summit will bring together India's most eminent faith leaders to identify what each can do to accelerate the pace of change.


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Carl E. "Chucky" Thompson (1968 – 9 de agosto de 2021) foi um produtor musical afro-americano de R&B e hip hop. Ele foi mais conhecido por ser membro da Bad Boy Entertainment e produzir álbuns de The Notorious B.I.G. e Mase.

Produtores musicais dos Estados Unidos


Bob Hope's pets were groomed here back in the day! Four Paws Only turned into a la Mutt "Where People Rock & Pets Rule" in 2008. Visit us for natural food, treats, cool accessories & professional grooming (by appointment please). Paws up!
Sarah Cioni is the Lead Designer and Artistic Director at Belle Terre Floral, a Toluca Lake based floral design studio that is known for its luscious, blossom-filled weddings and events.
In a serene park of native plants, within the heart of the ever burgeoning entertainment industry of the San Fernando Valley, sits an amazing treasure in California history. It is the very birthplace of the California we know today.
As an independent insurance broker firm, our first concern and focus is in fitting the policy to our client's needs and finances — not the other way around.
Educational Therapy, academic coaching, ISEE, HSPT, SAT, ACT and yoga for kids, teens, adults.
Providing mobile comprehensive assessments for adults and children. We assess for learning difficulties, Autism Spectrum Disorder, giftedness, ADHD or other behavioral/mood challenges, and for those seeking educational accommodations.
Our mission is to bring people together for the unparalleled experience of participating in the live arts. We strive to connect people through diverse storytelling and innovative performances.
Specializing in custom handmade and cad-cam rings, necklaces and bracelets of precious and semi-precious materials. Come visit our "eclectic" and friendly showroom on Riverside Drive !
We specialize in Residential, Commercial and Investment properties, in Toluca Lake and throughout Los Angeles. Our goal is to exceed your expectations in customer service!
A fully inclusive, affirming community of faith that serves as a visible beacon and an anchor of God's love in Toluca Lake and beyond. Worship services on Sundays at 10:30 am. All are welcome!
Graham Bloxham, his wife Natalie and their crew of experts bring over 40 years of automotive experience to the care of your vehicle. They currently service five generations of the world's most prestigious motor cars.
Our goal is providing our clients with high quality services and lasting experience. We use only the highest quality products such as EDS, OPI, SNS, Creative, and Gel.
LPQ Toluca Lake serves breakfast, lunch & dinner. We offer Free Wi-Fi, Organic Breads, Catering, a Kid's Menu and simple, sustainable food with fresh, wholesome ingredients.
Meet the continental quartet that famed film composer Hans Zimmer calls 'just amazing!' An enticing mix of French cabaret, hot gypsy jazz, bossa nova cool, Latin ballads, & anything that swings, Les Zazous performs with international flair & whimsy!
Enthusiastic web designers, computer geeks and marketers passionate about business growth, marketing & design. We are experts in marketing, website design, SEO, pay-per-click advertising and social media marketing for small to midsize businesses.
Toluca Lake's most trusted mechanic shop and gas station!
Metropolis Bikes is the Valley's premier bicycle shop with bikes for the entire family. We specialize in city bikes: cruisers, comfort, hybrids, single speeds, flat-bar road & Pedego electric bikes. Thanks for supporting your independent bike dealer!
Whether you are purchasing a new MINI, a pre-owned model, or bringing your car in for service, we are dedicated to providing our customers with a positive experience. Our philosophy distinguishes us from other dealerships.
Neumeister & Associates, Inc. is a full-service accounting firm that offers professional accounting and consulting services to a broad client base.
We Specialize in Private Dress-up tea parties.You are never too old to celebrate at Olivia's Dollhouse Tea Room! Whether you want a princess party or a tea party birthday party, Olivia's is perfect for any special occasion!
PC & Mac Computer Repair and Home Networking solutions company for Toluca Lake. We also set up and install Smart Homes, custom built gaming and servers.
Pergolina is a curious haven for adventurous souls; a home for gypsies, feathered with treasures to delight a structure made of love, mystery, curated beauty, an open heart, and open arms. Come visit.
We maintain a tradition of excellence in providing delicious coffees, teas, pastries, muffins and croissants. Lunchtime patrons enjoy sandwiches and other tasty treats! For the shoppers, we offer a variety of gifts, cards, and beautiful gift baskets.
Prosecco Trattoria provides delicious authentic Italian cuisine with attentive, personal service. Located in the heart of Toluca Lake, Prosecco has been pleasing the entertainment industry and loyal customers for over 18 years.
With a growing awareness pf nutritional values and dietary needs, please join us on our mission to discover new ways of living life to the full - by connecting with our food choices and embracing all the goodness that plant-based eating gives.
Associate real estate agent with Ramsey Shilling.
Red Maple Cafe • Gelato & Coffee Bar serves breakfast and lunch Mon-Fri and Brunch on Sat and Sun, including signature sandwiches, salads, bowls, artisan flatbread, shareables, authentic gelato & sorbet, VERVE coffee, RISHI teas, and baked goods.
Rose & Sage is a women's clothing and accessory boutique offering a personalized styling experience while you shop!
Located in beautiful Toluca Lake, inside the Toluca Lake Tennis and Fitness Club. We look forward to seeing you in the very near future. And yes! We are open to the public.
A past resident of beautiful Toluca Lake and a realtor serving the greater Toluca Lake area.
The Starbuck Jazz Quartet plays standards from the Great American Songbook as well as Bossa Nova and Latin Jazz. Great music for everyone to enjoy.
Tax and small business planning. We offer accounting, taxation, and small business consulting services with the personal touch.
Tina Smith Realtor, Sotheby's Int.
Tina Smith is a Residential & Commercial Realtor and California Native, ranging from multi-million-dollar Estates to first-home purchases to apartment buildings. Tina, her husband David and their rescue pets have resided in Toluca Lake since 2006.
The TLHA is committed to preserving a gracious, tranquil, family-friendly, and safe life for all residents of Toluca Lake. We are dedicated to protecting the unique "village" atmosphere that has distinguished our wonderful community since 1923.
Located next to Warner Brothers and Universal Studios, the Toluca Lake Tennis & Fitness Club offers superior tennis and fitness programs and facilities to Hollywood's entertainment industry professionals and everyone in the greater Toluca Lake area.
Victoria Reitz Interior Design offers complete interior design services. Victoria has over 25 years experience, is a past president of The American Society of Interior Designers, Los Angeles, and is on the board of the TLCC.
Visiting Angels is the nation's leading, nationally respected network of non-medical, private duty home care agencies providing senior care, elder care, and companion care to help the elderly and adults continue to live in their homes across America.
A trusted member of the Burbank Healthcare Community with over 25 years of experience providing chiropractic pain relief in a timely and caring manner.


The cornerstone of our firm is quality service in all aspects of our work.
TRIA ROBIT provides a full range of intellectual property services in the areas of patents, designs, trademarks and related matters. These include filing and prosecuting applications for patents, designs and trademarks, dealing with oppositions, revocations, appeals and other proceedings relating to granted IP rights, infringements and enforcement matters, search and watching services, renewals.
Agency TRIA ROBIT acts for a wide variety of clients based both in Latvia and Russia, and overseas. For these clients the firm acts in securing and advising on intellectual property rights in the countries of Central and Eastern Europe and Central Asia and the European Union. The firm also acts for many IP attorneys and law firms based overseas, assisting in the protection of their clients' intellectual property rights in the area.
We have many long-standing relationships with direct clients and foreign IP practices. This reflects the professionalism of our approach and our ability to provide fast, clear and consistent advice and assistance at reasonable fees. Our service is adopted to meet the varying needs of our clients.


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Stéphanie Seydoux
Stéphanie Seydoux is currently Head of the French Department for Women's rights and Gender Equaliy (pertaining to the Directorate-General for Social Cohesion).
She was previously involved in other areas of equality policies as head of the Departement for Equality promotion of the French Equality commission (Haute autorité de lutte contre les discriminations – HALDE) from 2007 to 2010, and as rapporteur for the High council for Integration in 2006 in charge of the Council's annual report (A comparative analysis of European integration models).
From 2004 to 2007, she was Deputy Head of the French Inspectorate General for Social Affairs, and contributed as an inspector to reports on various aspects of social policies (the enforcement of Labour laws, employment policies, hospital tarification).
A former diplomat, Stéphanie Seydoux was posted at the French Foreign office in Paris from 1992 to 1996 (Directorate for Americas and Economic and Financial Directorate) before serving in Moscow (1996-2000) and Kenya (2010-2013), as Deputy Head of Mission of the French Embassy.
She has a M.A in Modern Languages from Oxford University (St Hugh's College – 1988), a degree from the Institut d'études politiques de Paris (Sciences Po – 1991) and qualified from École nationale d'administration (ENA) in 2004 – promotion « Léopold Sédar Senghor ».


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The 2012 All-Ireland Under-21 Hurling Championship was the 48th staging of the All-Ireland championship since its establishment in 1964. The draw for the 2012 fixtures took place in late 2011. The championship began on 6 June 2012 and ended on 15 September 2012. Galway were the defending champions.

Clare won the All-Ireland final after defeating Kilkenny by 2-17 to 2-11.

Results

Leinster Under-21 Hurling Championship

Munster Under-21 Hurling Championship

Ulster Under-21 Hurling Championship

All-Ireland Under-21 Hurling Championship

Championship statistics

Miscellaneous

 Laois qualify for the Leinster final for the first time since the 1990 championship.
 Clare win their second ever Munster title.
 The All-Ireland semi-final meeting between Antrim and Clare is the teams' first meeting in the history of the championship.

Top scorers

Season

Single game

References

External links
 2012 Bord Gais Energy Munster GAA Hurling U21 Championship
 Bord Gais Energy Leinster G.A.A. U-21 H.C. 2012

Under-21
All-Ireland Under-21 Hurling Championship


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Sebastian Duda/Shutterstock.com
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How to Win a Furlough Appeal
Tens of thousands of employees challenged their loss of work (and income) during sequestration; a few were successful.
Eric Katz
Last summer, hundreds of thousands of federal employees were forced to take unpaid leave as agencies rushed to meet reduced spending caps imposed by the 2011 Budget Control Act.
Labor groups felt the mandatory furloughs were unfair and unnecessary, and they advised their members to appeal the decisions with the Merit Systems Protection Board. The small, quasi-judicial agency tasked with adjudicating personnel actions was quickly flooded with appeals from furloughed employees.
MSPB ultimately received 33,000 appeals. Most of those came from the Defense Department, which furloughed about 650,000 civilian workers. As a result, the board collected in a few months more than five times the number it typically receives in a year.
The unprecedented flood of appeals initially caused MSPB to delay any rulings indefinitely, but it has since begun to make its way through the employee challenges. The agency has adjudicated about 6,000 appeals to date, MSPB Chairman Susan Tsui Grundmann recently told Government Executive, and some employees have been successful.
Appeals first go to a regional administrative judge, who issues an initial ruling. If employees so choose, they may then issue a second appeal to the three-member, presidentially appointed and Senate-confirmed central panel.
In May, the MSPB panel overturned an initial decision in which an Army Corps of Engineers employee argued he should not have been subject to furloughs. Roger Dye maintained his position was misclassified, and that all his labor costs came from Civil Works or Intelligence Community sources of funding.
In order for MSPB to uphold a furlough, an agency must prove the temporary unpaid leave "promoted the efficiency of the service." The Defense Department determined in 2013 that any employees not paid by accounts included in the Defense-Military budget would be exempt from furloughs, because forcing them to not work "would not reduce the expenditure of the DoD budgetary resources and so would not assist in meeting reductions."
In its ruling, MSPB said Dye's position should have been classified as exempt from furloughs.
Grundmann said the cased was determined to be precedential, meaning all employees who can prove their job was classified under the wrong code will henceforth have their appeal upheld. MSPB has so far reversed 12 furlough decisions.
In Dye's case, he hasn't yet received back pay for his six days of furlough. The three-member panel remanded the case back to the regional administrative judge for further proceedings. The administrative judge, or the panel upon further appeal, will make a final determination on retroactive pay. The government could also appeal any such determination to the federal circuit.
(Image via Sebastian Duda/Shutterstock.com)
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Local coffee shops offer the best hangouts in the community and this mobile app makes them easy to find. BRÜ is packed with features like mobile ordering, loyalty programs, and a favorites system to quickly find the coffee you enjoy the most.
(HOUSTON) Texas, (ISSAQUAH) Washington – Coffee Fest is proud to announce a partnership with Inante LLC the creator of the BRÜmobileapp.com. Inante a technology start up in Houston created a new mobile e-commerce app that allows consumers to find a coffee shop near them, order on the app from their menu, and pick up when they get there.
Inante will be creating a special "local coffee shop" map to accompany Coffee Fest Nashville which will take place at Music City Center March 17-19 2017. The interactive map on Coffee Fest's website will feature coffee shops and cafes within a 10 mile radius of downtown Nashville and, it will be printed in the show guide as well. This map/app is being provided for attendees, exhibitors and sponsors of Coffee Fest that would like to get out into the neighborhoods and experience the coffee culture surrounding this great city. "We are thrilled to work with Coffee Fest to create their coffee/food vendor map at the upcoming Nashville Coffee Fest happening in March 2017", said Daniel Goebel, CEO of Inante, LLC. Inante's mission statement is to Empower Community Commerce. The independent coffee shop owner and consumer are the target for the app by leveling the playing field that larger, national chains have with loyalty programs, and their own apps, and the data generated that helps owners increase customer service and target marketing dollars. "We are pleased to work with Inante and have them and their new mobile app sponsor our interactive guide at Nashville next year", said David Heilbrunn, President of Coffee Fest, "we hope to continue the partnership with them at all three Coffee Fests next year." Coffee Fest started in 1992 is the largest independent coffee and tea trade show occurring three times a year in three different cities across the United States. Attendance at each event has been over 2000. To date more than 350,000 have attended and benefited from their time at Coffee Fest. You will find the leading retail education, training and workshops are also found at Coffee Fest.
About Coffee Fest: Coffee Fest is a trade only event serving the specialty coffee and gourmet tea industries since 1992. For more details about Coffee Fest, present and future or to see the winners of Coffee Fest competitions, IASC certified baristas and much more, visit www.coffeefest.com or become a fan at www.facebook.com/coffeefest and follow on Twitter @coffeefestshow.
About Inante LLC: Inante LLC, is based in Houston, Texas. BRUmobileapp.com or BRÜ is their first e-commerce product targeting independent coffee shops and the consumers that love them.


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FMCG »
Sunil Kataria
Five ways in which companies can negotiate a recession
A quick guide to negotiating a recession with a few strategies that some of India's best brands, agencies and retailers are already trying.ET Bureau | September 04, 2013, 09:03 IST
A quick guide to negotiating a recession with a few strategies that some of India's best brands, agencies and retailers are already trying:
1) Go Rural
At least for the next few months, India's vast rural markets look like they can be an effective bulwark against the recession. A meaningful rural marketing programme has never been either easy or inexpensive.
But brands across categories are hoping that an agrarian economy driven by a good monsoon will be liberal with disposable income. Also, given that it forms the bulk of the Indian market, it's simply too big to ignore.
According to Godrej's Sunil Kataria, "Rural markets are outpacing urban ones even at present. We will focus more on rural activation to tap the upsurge." Bundling brands is an effective strategy, justifying the cost of venturing into the hinterlands and familiarising the audience with new launches or products and categories that don't have too great a reach.
2) Go In-Store
The consumer durables category is no longer as ubiquitous a presence as it was on television a decade ago. Save a few like Samsung and Nokia, many brands in this space are not too active online either.
Where they spend the bulk of their efforts and money is often in store. Almost every brand worth its name has its network of exclusive stores — to say nothing of shop in shops in multi brand outlets — staffed by specially trained attendants whose job it is to convince the fence sitters and the browsers to leave the store as customers.
For retailers, it's quite possibly the best opportunity to start private labels. Explains Dr Siddharth S Singh, associate professor of marketing, ISB Hyderabad, "A company can invest in understanding the market, analysing how consumers are responding to difficulties and then focus its budget meeting their needs better. The likelihood of consumers trying and accepting private label brands is higher during tough times." Building these brands is more difficult and expensive during a boom period.
3) Go Syndicated
Tracking consumer trends and what the competition is doing is a marketing imperative. Like all such, it's also extremely expensive. Nielsen's Mathur sees an increasing trend towards more sectors opting for syndicated research projects where the expense, once split among different key players, becomes a lot more manageable.
4) Go Precise
Even among marketers that swear by television, there's an attempt to make the doughty old box work a lot harder. Inspired by neuroscience based research, brands are trying to create 10 second commercials that have all the impact of their 30 second siblings, at a fraction of the media and possibly production cost.
5) Go Forth
If you have capital burning a hole in your pocket, now's the best time to spend on certain aspects of the business that may otherwise have been out of reach.
Says Dentsu's Ohri, "Dominos is going ahead with its expansion plans since the real estate costs are down. Brands with a longterm vision of India don't consider the current turmoil a big deterrent."
In fact it could be a great time to build and strengthen the brand and brand relationships since small spends have greater visibility in this period of relative silence, points out Ajay Kakar, CMO - financial services, Aditya Birla Group.
Tags : Food & Entertainment, FMCG, Sunil Kataria, Rural markets, Godrej, Domino's


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'World's Sexiest Athlete' Alica Schmidt Takes A Break From Sport
German athlete Alica Schmidt has announced she is taking a break from the sport.The 400m runner qualified for the 2020 Olympics but was unable to secure a spot in either of the women's or mixed 4x400m relay events.
The 22-year-old ran personal bests in the lead-up to the Tokyo Games, but after watching the prestigious event from the sidelines, she is now taking a step back to reevaluate her future.
She took to Instagram and posted a series of training videos from this year. "Not gonna lie, I'm not satisfied with my races this year," she wrote
The 22-year-old impressed in the junior ranks, and she claimed silver at the 2017 European Athletics Under-20 Championship in the 4x400m relay according to Daily Star.
Schmidt has gained popularity on social media for her appearance but said she doesn't understand why she was awarded the title of 'Sexiest Athlete in the World' by Australian magazine Busted Coverage.


GameSpot has posted the full resolution version of Metal Gear Solid V: The Phantom Pain's Tokyo Game Show demo. Aside from the higher resolution, this version also includes English narration by Kojima Productions' Sean Eyestone, and English voices. Not that there is too much talking during the gameplay, but you can hear some Kiefer Sutherland and Robin Atkin Downes. Check out the video below.
Quiet isn't the only character with supernatural abilities. Like in past games, Snake will come across characters with different powers (Code Talker?).
You won't be able to select the regular soldiers as AI buddies.
You will not be able to play as Quiet, or any other buddy, just as Snake.
For the full interview, head over to GameSpot.


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