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EyeWorld - Eyeworld Weekly Update Archive - EW Weekly, April 15, 2016
EW Weekly, April 15, 2016
BromSite granted FDA approval
Largest eye study on Chinese Americans published
VEGF-A plays role in AMD and cataract
The U.S. Food and Drug Administration has granted approval for BromSite (bromfenac ophthalmic solution) 0.075% for the treatment of postoperative inflammation and prevention of ocular pain in patients undergoing cataract surgery, marketer Sun Ophthalmics (Princeton, New Jersey) said in a press release. BromSite is the first nonsteroidal anti-inflammatory drug approved in the U.S. to prevent pain. The compound is the first bromfenac solution formulated in DuraSite, a polymer-based formulation that can be used to improve solubility, absorption, bioavailability, and residence time as compared to conventional topical therapies, developed by InSite Vision (now a subsidiary of Sun Pharma, Mumbai, India). BromSite's approval was based on data from 2 multicenter, randomized, placebo-controlled phase 3 studies, where a significantly higher proportion of BromSite-treated patients were pain-free at day 1 post-surgery (77% and 82%) compared to patients treated with vehicle control (48% and 62%; p<0.001). Additionally, a significantly higher proportion of subjects administered BromSite were inflammation-free at day 15 post-cataract surgery (57% and 38%), compared to a vehicle control group (19% and 22%; p<0.001 and p=0.035, respectively).
The largest eye study on those with Chinese ancestry living in the U.S. found a higher percentage (85%) of neovascular or "wet" age-related macular degeneration (AMD) than geographic atrophy or "dry" AMD (15%), according to researchers at University of Southern California (USC) Roski Eye Institute, Los Angeles; this is almost directly opposite of what has been found in whites or other ethnic groups. The study found the prevalence of AMD is higher among Chinese Americans as compared to the Chinese population living in urban/rural China, suggesting the influence of environmental or behavioral factors should be considered. The other substantial finding in the study is that participants with diabetes (17.4%) were 3 times more likely than those without the disease to have significant visual impairment. This increase was found in the Chinese American study participants with type 2 diabetes who had cataracts or macular edema resulting in visual impairments. While 41% of these Chinese American study participants had diabetic retinopathy, this is a lower percentage than has been reported among Chinese people living in rural China (46%) and Latinos living in Los Angeles (48%).
Increased expression of the angiogenic factor VEGF-A promotes 3 common age-related eye conditions, both versions of age-related macular degeneration (AMD) and also cataracts, in an animal model, according to a press release from Massachusetts General Hospital, Boston. Using a mouse model in which VEGF-A is expressed at 2-3 times the normal level, similar to what is seen in aging humans, Alexander Marneros, MD, found this level of increased VEGF-A expression in the retina led to the kind of damage seen in both wet and dry AMD. A "surprising finding" was that VEGF-A was also expressed in the lens, which has no vascular system, and that its overexpression in the mouse model increased markers of oxidative stress in the lens and accelerated the formation of cataracts. IL-1β activation was found to be involved in dry AMD-like retinal damage seen in the mouse model, even at areas with no vascular overgrowth. But in strains of mice with both overexpression of VEGF-A and inactivation of certain genes essential to the NLRP3 inflammasome, the characteristic retinal degeneration did not appear, Dr. Marneros found. Overexpression of IL-1β was also seen in the lenses of mice with VEGF-A-induced cataracts.
A new paper in the American Journal of Ophthalmology evaluated the magnitude, with-the-rule (WTR) or against-the-rule (ATR) orientation, and vector components (Jackson astigmatic vectors [J0 and J45] and blurring strength) of the anterior and posterior corneal astigmatism (ACA and PCA) in patients with keratoconus. Mohammad Naderan, MD, and colleagues evaluated Pentacam (Oculus, Arlington, Washington) images to compare 1,273 patients with keratoconus and 1,035 normal age- and sex-matched participants. The mean magnitude of the ACA and PCA was 4.47±2.14 and 0.90±0.43 D, respectively. The dominant astigmatism orientation of the ACA was ATR in keratoconus patients and WTR in normal participants (p<0.001), while for the PCA it was WTR in keratoconus patients and ATR in normal participants (p<0.001). There was a significant agreement between the axis orientations of ACA and PCA in keratoconus patients (ĸ=0.077, p<0.001), but not in the normal group (p=0.626). ACA and PCA magnitude, M, J0, J45, and blur significantly increased by increasing keratoconus severity. There was a trend for increasing anterior ATR and posterior WTR and decreasing oblique astigmatism on both corneal surfaces by increasing the keratoconus severity according to the Amsler-Krumeich classification. A cutoff value of 1.8 D for ACA had 90.2% sensitivity and specificity, and that of 0.4 D for PCA had 89.5% sensitivity and 85.0% specificity for discriminating keratoconus from normal corneas.
Errors in IOL calculation for normal eyes after laser refractive treatment are related to the ratio of posterior-to-anterior corneal radius, according to a retrospective data analysis and validation study from A.K. Schuster and colleagues. They tested a new method of IOL calculation after corneal refractive surgery using Scheimpflug imaging (Pentacam HR) and partial coherence interferometry (PCI, IOLMaster, Carl Zeiss Meditec, Jena, Germany) that does not require historical data, the Schuster/Schanzlin-Thomas-Purcell (SToP) IOL calculator. The regression analysis study included 61 eyes (39 patients) that had LASIK (57 eyes) or photorefractive keratectomy (4 eyes) and subsequent cataract. Two factors were found that explained the deviation of the target refraction using the Holladay 1 formula; that is, the ratio of the corneal radii and the axial length and the ratio of corneal radii for the SRK/T formula. A new IOL adjustment calculator was derived and validated at a second center using 14 eyes (10 patients). The study is published in the Journal of Cataract & Refractive Surgery.
Coaxial micro-incision cataract surgery (C-MICS) was associated with less surgically induced astigmatism (SIA) 1 month after surgery than standard 2.75 mm incision cataract surgery (SICS), but differences were not statistically significant at final follow-up, indicating a faster refractive recovery with C-MICS than with SICS, according to prospective study from M.P. Czajka and colleagues. They evaluated 30 eyes (30 patients) scheduled to undergo combined phacoemulsification and 23-G vitrectomy and randomized them 1:1 to either C-MICS or SICS. Incision leakage occurred in 2 eyes (7%: 1 per group) and retinal break in 9 (30%: 4 in C-MICS, 5 in SICS). Fibrin in the anterior chamber occurred at day 1 in 3 eyes (10%: 2 C-MICS and 1 SICS). Posterior capsule opacification developed in 22 eyes (78%: 13 C-MICS, 9 SICS, p=0.1). A myopic shift of -0.63±0.7 was noted (-0.59±0.8 C-MICS, -0.68±0.6 SICS, p=0.74). SIA was significantly smaller in the C-MICS group at 1 month but not at final follow-up. The study is published in Acta Ophthalmologica.


Tristeza is one of the destructive diseases of citrus causing by citrus tristeza virus (CTV). Historically, CTV has been associated with serious outbreaks of quick decline of citrus, therefore CTV monitoring is important aspect for avoiding such re-emerging epidemics, which would threat citrus production through the world. In this context, we have designed for the first time a label-free impedimetric biosensor for the detection of nucleic acid of CTV. The sensing platform based on a screen-printed carbon electrode (SPCE) was modified by electrodeposited gold nanoparticles (AuNPs), which allowed to efficiently immobilizing thiolated ssDNA probes as well to enhance the electrode conductivity. The growth of AuNPs was optimized and characterized using scanning electron microscopy (SEM), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). We investigated the behavior of thiolated ssDNA probe layer and its hybridization with target DNA onto AuNP surfaces by EIS measurements in Fe(CN6)4-/Fe(CN6)3- red-ox system. The main sensor design aspects such as AuNPs size, probe DNA concentration and immobilization time together with DNA hybridization time were optimized so as to achieve the best performance. Impedance values of DNA hybridization increased with Citrus tristeza-related synthetic DNA concentration, showing a logarithmic relation in the range of 0.1–10 μM. The results also indicate that the biosensor was able to selectively detect CTV nucleic acids in the presence of other non-specific DNAs. Moreover, we have demonstrated the good performance of the system in a real plant sample matrix. In addition, the sensor reproducibility enhanced after the hybridization onto MCH/poly (AT) thiolated DNA probes which was confirmed by intra- and inter-day variability assays.


All the other skiers had left for the slopes and one of the chalet girls was pouring me another cup of coffee when Sue came down.
"Not going up?" Sue wasn't a skier herself. She'd tagged along with her husband in the hope of getting some photography done.
"My knees have given out."
"You can come with me on an expedition," she slapped a hand on one of my knees and massaged it forcibly, "it'll loosen them up."
I left her with her croissant and went up to my room for my jacket and stuff. Soon we were out in the sun and snow, tall thin me looking down on the curly auburn mop sticking out of the top of Sue's headband.
I wrestled with the strap of her camera bag, trying to find a comfortable spot on my shoulder. It was hot under the alpine sun, and I unzipped my jacket as we started down the road.
"You be careful with that," she said as the strap slipped down to my elbow. As I struggled to get it back onto my shoulder we turned a corner and she saw down into the valley. "Oh, no."
All we could see was the pine forest and the road winding down through it into a layer of cloud, opaque as cotton wool. "We could go up instead," I suggested.
Sue examined the camera round her neck, whether it would cope in the dim light. "I've got enough skiing photos," she said, "like postcards."
We set off downwards. One of those alpine roads, a strip of tarmac in long zigzags down the mountainside, coaches and cars coming at you round sharp bends. It makes for a lot of walking, normally compensated for by the view. Today there was only the floor of cloud, hurting our eyes where the sunlight fell on it. The mountain on the opposite side of the valley was a grey and green wall, blocking out any view of the alps beyond.
At the first bend we came across a Lady Shrine. I knew Sue would have to take a photo of this, but I didn't think I'd have to stand beside it.
"I'm surprised you'd want a photo of my ugly mug."
"Need someone in the photograph to establish the scale," she said.
"And here's me thinking you only brought me to carry your bag."
So I stood with a grin beside this little shrine. All the photos I've seen of myself show a long miserable face at best, a twisted grin at worst. If I've had better moments, no camera ever caught them.
Sue didn't press the button anyway. "Could you kneel down in front of it like a peasant?"
"Do I look like a peasant?" I drew the backs of my fingers down my yellow and purple skiing jacket.
I kneeled down, glad there was no traffic around to see how stupid I looked. Eerie, staring into the Virgin's blank eyes while the camera clicked.
My knees creaked as I stood up. It was getting cold in the shade of the mountain and I was glad of the extra work generated by the weight of the camera bag.
"So what did you pray for?" she smiled.
"That my knees will hold out on the way back."
The cloud layer turned out to be an ordinary mist, not the pea-souper we had expected. But cold. I pulled my ski hat down over my ears and arranged my scarf around my neck like lagging. It was such a cold as seemed to sink right into my face and head. Sue had only her headband to keep her ears warm. I noticed she didn't have a scarf. I offered her mine but she wouldn't take it.
We went on down the road stamping our feet at times and listening out for passing vehicles. We discussed the possibility of going straight down through the pines, which stood in deep snow. Here within the cloud layer they were covered in frost like white plastic Christmas trees. The town had looked very near on the map, but this road swung back and forth so much that we began to realise it was going to take us a couple of hours to get there. We did try a brief foray into the deep snow, which convinced us that going straight down would land us in worse trouble.
There wasn't much worth photographing amongst the trees, tarmac and mist. The mountainside opposite faded to a spectral backdrop of forest and grey rock, then vanished behind a pure white wall of cloud. With half our universe blanked out, the idea that we could be sucked off the mountainside into nothingness seemed plausible.
There was a stream running down the mountain, and in the middle of each stretch of road it fed into a large drainpipe which channelled it under and out on the other side. So we kept coming across it, and I noticed that whenever it went over a drop in its descent it would be frozen on top so that there was an umbrella of ice suspended over the water, and on top of the umbrella, a layer of snow. Every time we approached the stream, I tried to keep Sue talking, to keep her from thinking of photographing it. All I wanted was to get to the town below for some coffee or hot wine. It might sound petty, but it wasn't the sort of cold anyone could stand still in for long.
On one pass of the stream I suggested we just go back up to the chalet, but she wasn't about to abandon the expedition with just one photograph. On the next pass I said, "That's going to be a stupid photo, me at that shrine."
"I'll get it enlarged and paint over it," she said, "make you some pilgrim."
I had to think about this for a minute. "Isn't that cheating?"
"Yes, if you've got rules." I wasn't sure if she was serious, but the stream was behind us and I didn't say any more. The air was so cold my throat felt raw from talking, and I had to swallow sometimes to try and keep it warm.
A phenomenon arose at the roadside that Sue just had to stop and photograph: tiny flowers of ice and frost were growing on the rocks, on the blades of frozen grass, on the bark of the trees, but she couldn't find anything to show the scale, the intricacy of the tiny white flowers. She gets the camera bag off my shoulder and tries different lenses, she takes off a glove and fetches a five centime piece from her pocket, but she's not taking photographs for a catalogue. "There's never a beetle when you need one!"
"Not in this weather," I said.
She had to admit defeat. When we finally emerged below the cloud layer it seemed almost warm. There was the town, or you might have called it a large village, just a few hundred yards below, and a grey sky above. We had walked down through that town's sky.
The houses weren't arranged regularly like in a modern town, but whatever interest might have been found in variations of size, shape and positioning, was lost in the uniformity of colour. The walls and shutters were all done over in yellow and green pastel, dirty and faded.
Many of the shutters were closed, although some windows, presumably kitchen windows, were open. There was hardly anyone about in the streets, and when we looked at our watches it was ten past eleven. We had arrived at the start of the long French lunch.
We exchanged bonjours with two men who came by, and asked them when we could get a bus back up. In two hours, they said.
There seemed to be no cafés or restaurants. The only place we could find with food was a small supermarket, closed.
Sue groaned. "When will they be open again?"
"It's usually three o'clock." I started to get a headache as I contemplated the road we had come. This time we would be colder, hungrier, and walking uphill. A light drizzle started to fall.
"Well, things certainly can't get any worse," said Sue. A smell of onion soup and cheese began to reach us from the windows.
We found a haberdashery that was open, the only staff in attendance being a slim woman in her fifties who must have realised that we had only gone in for the warmth. Instead of trying to sell Sue something warm and woolly in the way of scarves or hats, she suggested she try some of the ladies millinery, offering her a blue silk scarf. Sue put her camera down on the counter and wrapped the scarf round her neck, looking at herself in the mirror without much interest.
The woman raised an index finger as if to say, "I have just the thing to go with that," and brought out a large dark blue hat which took up most of the counter space. She was probably bored but we were happy to humour her as long as we could stay in the warm until the bus came.
"I don't look good in hats," said Sue, but we talked her into trying it. She stretched her arms wide to pick up the hat by opposite sides of the rim and carefully lowered it onto her head, examining herself in the mirror. Her curls formed a ring against the dark blue, a copper-leaf nimbus. I reached for the camera when she started to turn towards me. She whisked the hat off as soon as she realised, but not soon enough.
A few weeks later she sent me the photograph with a note, Told you I didn't look good in hats!
The camera with its face-on flash certainly hadn't paid her any complements. The flesh was pale, the hair garish, and the rim of the hat had been missed, beyond the edge of the frame. The surprised look in her eyes had unfortunately been perfectly captured. It was a hurried, stolen photograph, so what could I expect? But the stolen moments are the ones you want to keep.
Over the past year I've had to go to a drawing class to learn to draw faces, and a painting class to learn about flesh tones. I can do a good face now, though not always a good likeness. I thought painting the hat as a dark blue disk would be easy after that, but I had to experiment a lot to get a texture that was dark without looking funereal.
I've got that and now I'm on the hair. Thick orange brush strokes, but each one has to be just right.
When I'm finished, I'll start on something else. People on a mountainside with half their universe blotted out. A drab town with interesting things going on in the kitchens. A stream with an umbrella of ice and snow. Perhaps all in one picture, my masterpiece, but that's looking ahead. Right now I'm learning to do a woman in a hat.
© Sandy Fleemin 2003. First published in Takahe 31 (ISSN 0114-4138).


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AN ACT RELATIVE TO UNIFORM ADULT GUARDIANSHIP AND PROTECTIVE PROCEEDINGS JURISDICTION
SECTION 1. Section 1-301 of chapter 190B of the General Laws, as appearing in the 2012 Official Edition, is hereby amended by striking out, in line 3, the word "decedents," and inserting in place thereof the following words:- decedents and.
SECTION 2. Said section 1-301 of said chapter 190B, as so appearing, is hereby further amended by striking out, in lines 3 and 4, the words ", and persons to be protected,".
SECTION 3. Said section 1-301 of said chapter 190B, as so appearing, is hereby further amended by inserting after the word "persons", in line 7, the following words:- , protected persons.
SECTION 4. Subsection (c) of section 1-302 of said chapter 190B, as so appearing, is hereby amended by adding the following sentence:- Part 2 of Article 5A provides the exclusive jurisdictional basis for a court of the commonwealth to appoint a guardian or issue a protective order for an adult.
SECTION 5. Section 4-201 of said chapter 190B, as so appearing, is hereby amended by striking out subsections (d) and (e).
SECTION 6. Section 4-202 of said chapter 190B, as so appearing, is hereby amended by striking out, in lines 5 and 6, the words "or local guardian or conservator".
SECTION 7. Section 4-203 of said chapter 190B, as so appearing, is hereby amended by striking out, in lines 3 and 4 and 5, the words "or nonresident protected person", each time it appears.
SECTION 8. Said section 4-203 of said chapter 190B, as so appearing, is hereby further amended by striking out, in lines 6 and 7, the words "or belonging to the nonresident protected person".
SECTION 9. Said section 4-203 of said chapter 190B, as so appearing, is hereby further amended by striking out, in lines 8 and 9, the words ", guardian or conservator".
SECTION 10. Section 4-206 of said chapter 190B, as so appearing, is hereby amended by striking out the second paragraph.
SECTION 11. The definition of "Protected person" in section 5-101 of said chapter 190B, as so appearing, is hereby amended by striking out, in line 80, the words "and 5-408" and inserting in place thereof the following words:- , 5-408 and Article 5A.
SECTION 12. Section 5-105 of said chapter 190B, as so appearing, is hereby amended by inserting after the word "resides", in line 11, the following words:- or is present.
SECTION 13. Section 5-431 of said chapter 190B, as so appearing, is hereby amended by inserting after the word "conservator", in lines 3 and 5, the words "for a minor", in each instance.
SECTION 14. Said section 5-431 of said chapter 190B, as so appearing, is hereby further amended by striking out, in lines 5 and 7, the words "protected person" and inserting in place thereof, in each instance, the following word:- minor.
SECTION 15. Said section 5-431 of said chapter 190B, as so appearing, is hereby further amended by striking out, in line 13, the words "ward, incapacitated or protected person" and inserting in place thereof the following word:- minor.
SECTION 16. Chapter 190B of the General Laws is hereby further amended by inserting after Article V the following Article:-
ARTICLE 5A
UNIFORM ADULT GUARDIANSHIP AND PROTECTIVE PROCEEDINGS JURISDICTION ACT
Section 5A-101. [Short Title.]
Article 5A shall be known and may be cited as the Uniform Adult Guardianship and Protective Proceedings Jurisdiction Act.
Section 5A-102. [Definitions.]
As used in this Article, the following terms shall have the following meanings:
(1) "Adult", an individual who has attained 18 years of age.
(2) "Conservator", a person appointed by the court to administer the property of an adult, including a person appointed under Part 4 of Article V.
(3) "Guardian", a person appointed by the court to make decisions regarding the person of an adult, including a person appointed under Part 3 of Article V.
(4) "Guardianship order", an order appointing a guardian.
(5) "Guardianship proceeding", a judicial proceeding in which an order for the appointment of a guardian is sought or has been issued.
(6) "Incapacitated person", an adult for whom a guardian has been appointed.
(7) "Party", the respondent, petitioner, guardian, conservator or any other person allowed by the court to participate in a guardianship or protective proceeding.
(8) "Person", except in the term "incapacitated person" or "protected person", an individual, corporation, business trust, estate, trust, partnership, limited liability company, association, joint venture, public corporation, government or governmental subdivision, agency or instrumentality or any other legal or commercial entity.
(9) "Protected person", an adult for whom a protective order has been issued.
(10) "Protective order", an order appointing a conservator or other order related to management of an adult's property.
(11) "Protective proceeding", a judicial proceeding in which a protective order is sought or has been issued.
(12) "Record", information that is inscribed on a tangible medium or that is stored in an electronic or other medium and is retrievable in perceivable form.
(13) "Respondent", an adult for whom a protective order or the appointment of a guardian is sought.
(14) "State", a state of the United States, the District of Columbia, Puerto Rico, the United States Virgin Islands, a federally recognized Indian tribe or a territory or insular possession subject to the jurisdiction of the United States.
Section 5A-103. [International Application of the Uniform Adult Guardianship and Protective Proceedings Jurisdiction Act.]
A court of the commonwealth may treat a foreign country as if it were a state for the purpose of applying Parts 1, 2, 3 and 5 of the uniform adult guardianship and protective proceedings jurisdiction act.
Section 5A-104. [Communication Between Courts.]
(a) A court of the commonwealth may communicate with a court in another state concerning a proceeding arising under the Uniform Adult Guardianship and Protective Proceedings Jurisdiction Act. The court may allow the parties to participate in the communication. Except as otherwise provided in subsection (b), the court shall make a record of the communication. The record may be limited to the fact that the communication occurred.
(b) Courts may communicate concerning schedules, calendars, court records and other administrative matters without making a record.
Section 5A-105. [Cooperation Between Courts.]
(a) In a guardianship or protective proceeding in the commonwealth, a court of the commonwealth may request the appropriate court of another state to do any of the following:
(1) hold an evidentiary hearing;
(2) order a person in that state to produce evidence or give testimony pursuant to procedures of that state;
(3) order that an evaluation or assessment be made of the respondent;
(4) order any appropriate investigation of a person involved in a proceeding;
(5) forward to the court of the commonwealth a certified copy of the transcript or other record of a hearing under paragraph (1) or any other proceeding, any evidence otherwise produced under paragraph (2) and any evaluation or assessment prepared in compliance with an order under paragraph (3) or (4);
(6) issue any order necessary to assure the appearance in the proceeding of a person whose presence is necessary for the court to make a determination, including the respondent or the incapacitated or protected person;
(7) issue an order authorizing the release of medical, financial, criminal or other relevant information in that state, including protected health information as defined in 45 C.F.R. 160.103, as amended.
(b) If a court of another state in which a guardianship or protective proceeding is pending requests assistance of the kind provided in subsection (a), a court of the commonwealth has jurisdiction for the limited purpose of granting the request or making reasonable efforts to comply with the request.
Section 5A-106. [Taking Testimony In Another State.]
(a) In a guardianship or protective proceeding, in addition to other procedures that may be available, testimony of a witness who is located in another state may be offered by deposition or other means allowable in the commonwealth for testimony taken in another state. The court on its own motion may order that the testimony of a witness be taken in another state and may prescribe the manner in and the terms upon which the testimony is to be taken.
(b) In a guardianship or protective proceeding, a court in the commonwealth may permit a witness located in another state to be deposed or to testify by telephone or audiovisual or other electronic means. A court of this state shall cooperate with the court of the other state in designating an appropriate location for the deposition or testimony.
(c) Documentary evidence transmitted from another state to a court of the commonwealth by technological means that do not produce an original writing shall not be excluded from evidence on an objection based on the best evidence rule.
Section 5A-201. [Definitions; Significant Connection Factors.]
(a) As used in this part, the following terms shall have the following meaning:
(1) "Emergency", a circumstance that will likely result in substantial harm to a respondent's health, safety or welfare and for which the appointment of a guardian is necessary because no other person has authority and is willing to act on the respondent's behalf.
(2) "Home state", the state in which the respondent was physically present, including any period of temporary absence, for at least 6 consecutive months immediately before the filing of a petition for a protective order or the appointment of a guardian; provided, however, that if there is no such state then the state in which the respondent was physically present, including any period of temporary absence, for at least 6 consecutive months ending within the 6 months prior to the filing of the petition.
(3) "Significant-connection state", a state, other than the home state, with which a respondent has a significant connection other than mere physical presence and in which substantial evidence concerning the respondent is available.
(b) In determining under section 5A-203 and subsection (e) of section 5A-301 if a respondent has a significant connection with a particular state, the court shall consider:
(1) the location of the respondent's family and other persons required to be notified of the guardianship or protective proceeding;
(2) the length of time the respondent was physically present in the state at any time and the duration of any absence;
(3) the location of the respondent's property; and
(4) the extent to which the respondent has ties to the state, such as voting registration, state or local tax return filing, vehicle registration, driver's license, social relationship and receipt of services.
Section 5A-202. [Exclusive Basis.]
Part 2 of this Article provides the exclusive jurisdictional basis for a court of the commonwealth to appoint a guardian or issue a protective order for an adult.
Section 5A-203. [Jurisdiction.]
A court of the commonwealth has jurisdiction to appoint a guardian or issue a protective order for a respondent if:
(1) the commonwealth is the respondent's home state;
(2) on the date the petition is filed, the commonwealth is a significant-connection state and:
(A) the respondent does not have a home state or a court of the respondent's home state has declined to exercise jurisdiction because the commonwealth is a more appropriate forum; or
(B) the respondent has a home state, a petition for an appointment or order is not pending in a court of that state or another significant-connection state and, before the court makes the appointment or issues the order:
(i) a petition for an appointment or order is not filed in the respondent's home state;
(ii) an objection to the court's jurisdiction is not filed by a person required to be notified of the proceeding; and
(iii) the court in the commonwealth concludes that it is an appropriate forum under the factors in section 5A-206;
(3) the commonwealth does not have jurisdiction under either paragraph (1) or (2), the respondent's home state and all significant-connection states have declined to exercise jurisdiction because the commonwealth is the more appropriate forum and jurisdiction in the commonwealth is consistent with the constitutions of the commonwealth and the United States; or
(4) the requirements for special jurisdiction under section 5A-204 are met.
Section 5A-204. [Special Jurisdiction.]
(a) A court of the commonwealth lacking jurisdiction under paragraphs (1) to (3), inclusive, of section 5A-203 has special jurisdiction to:
(1) appoint a guardian in an emergency for a respondent who is physically present in the commonwealth for a term not exceeding 90 days; provided, however, that upon a finding of extraordinary circumstances set forth in its order, the court may order an appointment for a longer period to a date certain; and provided further, that the court may for good cause shown extend the appointment for additional 90 day periods;
(2) issue a protective order with respect to real or tangible personal property located in the commonwealth;
(3) appoint a guardian or conservator for an incapacitated or protected person for whom a provisional order to transfer the proceeding from another state has been issued under procedures similar to section 5A-301.
(b) If a petition for the appointment of a guardian in an emergency is brought in the commonwealth and the commonwealth was not the respondent's home state on the date the petition was filed, the court shall dismiss the proceeding at the request of the court of the home state, if any, whether dismissal is requested before or after the emergency appointment.
Section 5A-205. [Exclusive and Continuing Jurisdiction.]
Except as otherwise provided in section 5A-204, a court that has appointed a guardian or issued a protective order consistent with this Article shall have exclusive and continuing jurisdiction over the proceeding until it is terminated by the court or the appointment or order expires by its own terms.
Section 5A-206. [Appropriate Forum.]
(a) A court of the commonwealth that has jurisdiction under section 5A-203 to appoint a guardian or issue a protective order may decline to exercise its jurisdiction if the court determines, at any time, that a court of another state is a more appropriate forum.
(b) If a court of the commonwealth declines to exercise its jurisdiction under subsection (a), it shall either dismiss or stay the proceeding. The court may impose any condition the court considers just and proper, including the condition that a petition for the appointment of a guardian or issuance of a protective order be filed promptly in another state.
(c) In determining whether it is an appropriate forum, the court shall consider all relevant factors, including:
(1) any expressed preference of the respondent;
(2) whether abuse, neglect or exploitation of the respondent has occurred or is likely to occur and which state could best protect the respondent from the abuse, neglect or exploitation;
(3) the length of time the respondent was physically present in or was a legal resident of the commonwealth or another state;
(4) the distance of the respondent from the court in each state;
(5) the financial circumstances of the respondent's estate;
(6) the nature and location of the evidence;
(7) the ability of the court in each state to decide the issue expeditiously and the procedures necessary to present evidence;
(8) the familiarity of the court of each state with the facts and issues in the proceeding; and
(9) if an appointment was made, the court's ability to monitor the conduct of the guardian or conservator.
Section 5A-207. [Jurisdiction Declined by Reason of Conduct.]
(a) If at any time a court of the commonwealth determines that it acquired jurisdiction to appoint a guardian or issue a protective order because of unjustifiable conduct, the court may:
(1) decline to exercise jurisdiction;
(2) exercise jurisdiction for the limited purpose of fashioning an appropriate remedy to ensure the health, safety and welfare of the respondent or the protection of the respondent's property or prevent a repetition of the unjustifiable conduct, including staying the proceeding until a petition for the appointment of a guardian or issuance of a protective order is filed in a court of another state having jurisdiction; or
(3) continue to exercise jurisdiction after considering:
(A) the extent to which the respondent and all persons required to be notified of the proceedings have acquiesced in the exercise of the court's jurisdiction;
(B) whether it is a more appropriate forum than the court of any other state under the factors in subsection (c) of section 5A-206; and
(C) whether the court of any other state would have jurisdiction under factual circumstances in substantial conformity with the jurisdictional standards of section 5A-203.
(b) If a court of the commonwealth determines that it acquired jurisdiction to appoint a guardian or issue a protective order because a party seeking to invoke its jurisdiction engaged in unjustifiable conduct, it may assess against that party necessary and reasonable expenses, including attorney's fees, investigative fees, court costs, communication expenses, witness fees and expenses and travel expenses. The court may not assess fees, costs or expenses of any kind against the commonwealth or a governmental subdivision, agency or instrumentality of the commonwealth unless authorized by law other than the Uniform Adult Guardianship and Protective Proceedings Jurisdiction Act.
Section 5A-208. [Notice of Proceeding.]
If a petition for the appointment of a guardian or issuance of a protective order is brought in the commonwealth and the commonwealth was not the respondent's home state on the date the petition was filed, in addition to complying with the notice requirements of the commonwealth, notice of the petition shall be given to those persons who are entitled to notice of the petition if a proceeding were brought in the respondent's home state. The notice shall be given in the same manner as notice is required to be given in the commonwealth.
Section 5A-209. [Proceedings in More than One State.]
Except for a petition for the appointment of a guardian in an emergency or issuance of a protective order limited to property located in the commonwealth under paragraph (1) or (2) of subsection (a) of section 5A-204, if a petition for the appointment of a guardian or issuance of a protective order is filed in the commonwealth and in another state and neither petition has been dismissed or withdrawn, the following rules apply:
(1) If the court in the commonwealth has jurisdiction under section 5A-203, it may proceed with the case unless a court in another state acquires jurisdiction under provisions similar to section 5A-203 before the appointment or issuance of the order.
(2) If the court in the commonwealth does not have jurisdiction under section 5A-203, whether at the time the petition is filed or at any time before the appointment or issuance of the order, the court shall stay the proceeding and communicate with the court in the other state. If the court in the other state has jurisdiction, the court in the commonwealth shall dismiss the petition unless the court in the other state determines that the court in the commonwealth is a more appropriate forum.
TRANSFER OF GUARDIANSHIP OR CONSERVATORSHIP
Section 5A-301. [Transfer of Guardianship or Conservatorship to Another State.]
(a) A guardian or conservator appointed in the commonwealth may petition the court to transfer the guardianship or conservatorship to another state.
(b) Notice of a petition under subsection (a) shall be given to the persons entitled to notice of a petition in the commonwealth for the appointment of a guardian or conservator.
(c) On the court's own motion or at the request of the guardian or conservator, the incapacitated or protected person or other person required to be notified of the petition, the court shall hold a hearing on a petition filed pursuant to subsection (a).
(d) The court shall issue an order provisionally granting a petition to transfer a guardianship and shall direct the guardian to petition for guardianship in the other state if the court is satisfied that the guardianship will be accepted by the court in the other state and the court finds that:
(1) the incapacitated person is physically present in or is reasonably expected to move permanently to the other state;
(2) an objection to the transfer has not been made or, if an objection has been made, the objector has not established that the transfer would be contrary to the interests of the incapacitated person; and
(3) plans for care and services for the incapacitated person in the other state are reasonable and sufficient.
(e) The court shall issue a provisional order granting a petition to transfer a conservatorship and shall direct the conservator to petition for conservatorship in the other state if the court is satisfied that the court of the other state will accept the conservatorship and the court finds that:
(1) the protected person is physically present in or is reasonably expected to move permanently to the other state, or the protected person has a significant connection to the other state considering the factors in subsection (b) of section 5A-201;
(2) an objection to the transfer has not been made or, if an objection has been made, the objector has not established that the transfer would be contrary to the interests of the protected person; and
(3) adequate arrangements will be made for management of the protected person's property.
(f) The court shall issue a final order confirming the transfer and terminating the guardianship or conservatorship upon its receipt of:
(1) a provisional order accepting the proceeding from the court to which the proceeding is to be transferred which is issued under provisions similar to section 5A-302; and
(2) the documents required to terminate a guardianship or conservatorship in the commonwealth.
Section 5A-302. [Accepting Guardianship or Conservatorship Transferred from Another State.]
(a) To confirm the transfer of a guardianship or conservatorship to the commonwealth under provisions similar to section 5A-301, the guardian or conservator shall petition the court in the commonwealth to accept the guardianship or conservatorship. The petition shall include a certified copy of the other state's provisional order of transfer.
(b) Notice of a petition under subsection (a) shall be given to those persons entitled to notice if the petition was a petition for the appointment of a guardian or issuance of a protective order in both the transferring state and the commonwealth. The notice shall be given in the same manner as notice is required to be given in the commonwealth.
(c) On the court's own motion or at the request of the guardian or conservator, the incapacitated or protected person or other person required to be notified of the proceeding, the court shall hold a hearing on a petition filed pursuant to subsection (a).
(d) The court shall issue an order provisionally granting a petition filed under subsection (a) unless:
(1) an objection is made and the objector establishes that transfer of the proceeding would be contrary to the interests of the incapacitated or protected person; or
(2) the guardian or conservator is ineligible for appointment in the commonwealth.
(e) The court shall issue a final order accepting the proceeding and appointing the guardian or conservator as guardian or conservator in the commonwealth upon the court's receipt from the court from which the proceeding is being transferred of a final order issued under provisions similar to section 5A-301 transferring the proceeding to the commonwealth.
(f) Not later than 90 days after the issuance of a final order accepting the transfer of a guardianship or conservatorship, unless otherwise ordered, the court shall determine whether the guardianship or conservatorship needs to be modified to conform to the laws of the commonwealth.
(g) In granting a petition under this section, the court shall recognize a guardianship or conservatorship order from the other state, including the determination of the incapacitated or protected person's incapacity and the appointment of the guardian or conservator.
(h) The denial by a court of the commonwealth of a petition to accept a guardianship or conservatorship transferred from another state does not affect the ability of the guardian or conservator to seek appointment as guardian or conservator in the commonwealth under Parts 3 and 4 of Article V.
REGISTRATION AND RECOGNITION OF ORDERS FROM OTHER STATES
Section 5A-401. [Registration of Guardianship Orders.]
If a guardian has been appointed in another state and a petition for the appointment of a guardian is not pending in the commonwealth, the guardian appointed in the other state, after giving notice to the appointing court of an intent to register, may register the guardianship order in the commonwealth by filing, as a foreign judgment, in an appropriate division of the probate and family court where an original proceeding could be filed, certified copies of the order and letters of office and of any bond.
Section 5A-402. [Registration of Protective Orders.]
If a conservator has been appointed in another state and a petition for a protective order is not pending in the commonwealth, the conservator appointed in the other state, after giving notice to the appointing court of an intent to register, may register the protective order in the commonwealth by filing, as a foreign judgment in a court of the commonwealth, in a division of the probate and family court in which property belonging to the protected person is located, certified copies of the order and letters of office and of any bond.
Section 5A-403. [Effect of Registration.]
(a) Upon registration of a guardianship or protective order from another state, the guardian or conservator may exercise in the commonwealth all powers authorized in the order of appointment except those powers prohibited under the laws of the commonwealth, including maintaining actions and proceedings in the commonwealth and, if the guardian or conservator is not a resident of the commonwealth, subject to any conditions imposed upon nonresident parties.
(b) A court of the commonwealth may grant any relief available under this Article and other laws of the commonwealth to enforce a registered order.
Section 5A-501. [Uniformity of Application and Construction.]
In applying and construing this Article, consideration shall be given to the need to promote uniformity of the law with respect to its subject matter among states that enact it.
Section 5A-502. [Relation to Electronic Signatures in Global and National Commerce Act.]
This Article modifies, limits and supersedes the federal Electronic Signatures in Global and National Commerce Act, 15 U.S.C. 7001, et seq., but shall not modify, limit or supersede section 101(c) of that act, 15 U.S.C. Section 7001(c), or authorize electronic delivery of any of the notices described in section 103(b) of that act, 15 U.S.C. Section 7003(b).
Section 5A-503. [Transitional Provision.]
(a) This Article shall apply to guardianship and protective proceedings begun on or after January 1, 2015.
(b) Parts 1, 3 and 4 and section 5A-501 and section 5A-502 shall apply to proceedings begun before January 1, 2015 regardless of whether a guardianship or protective order has been issued.
SECTION 17. This act shall take effect on January 1, 2015.

redpajama_set_name: RedPajamaCommonCrawl


Driven by a high volume of requests by HR Managers and Training Directors, last August we published the Top 10 eLearning Content Development Companies for 2013. Since eLearning Industry is rapidly evolving, it is high time to publish the Top 10 eLearning Content Development Companies for 2014. Surprisingly enough, the resemblance between the two lists is weak; 7 out of 10 companies included in the Top 10 eLearning Content Development Companies for 2014 are new additions!
The top eLearning content development companies for 2014 were selected based on 7 criteria (8 criteria were used –revealing our cards here!– for our Top eLearning Content Development Companies For 2018).
Nonetheless, it is important to highlight that you need to make further your own research in order to choose the company that will better serve your needs and preferences. Hence, I suggest you visit and review the official sites of each eLearning content development company to get the full picture of the Top 10 eLearning Content Development Companies' services.
Are you a Top eLearning Content Provider? Create a Free Listing on eLearning Industry, the largest and fastest growing independent online community for eLearning Professionals!
SweetRush is about 100 people strong, been in business since 2001, and, similar to most companies in the industry, is comprised of instructional designers (of various flavors), creative multimedia developers, project and program managers, solution architects, and engineers. However, beyond the similarities, we like to promote that we are different, as we say, in a good way.
We have a unique culture that is validated by our near-zero turnover. Our institutionalized culture is based on the concept of caring: caring about each other, our clients, and the planet. Keeping the same crew means that each of our divisions are headed up and populated by accomplished and synchronized veterans - committed, talented, and team-oriented people.
We have excellent sustained working relationships with a very significant roster of Fortune 500 clients. We excel at innovative blended solutions, handle multi-million dollar projects from analysis to delivery, and are leaders in leveraging technology, such as mobile and gamification.
We've committed to custom technology development from inception and have a particularly strong engineering team. Our creative team is simply the best, and we win many projects based upon our focus on project management. Our IDs are obsessively learner-centric and focused on analysis and our clients' business drivers.
City & Guilds Kineo helps the world's leading businesses improve performance through learning and technology.
We provide full learning solutions for key areas including compliance, onboarding, leadership and management, and sales and channel partners.
We're currently Learning Provider of the Year, Elearning Company of the Year, and 4 times winners at the LearnX awards. But we're in it for results, not awards. Ask McDonald's, Compass, Sony and many more how we've delivered a great experience and results for them.
We're global, with 150 people in the UK and over 100 in the US, Asia Pacific and beyond. As part of the City & Guilds group, we can support you in over 80 countries.
We love to share: visit our website for free resources, case studies and more.
For 20 years, Bottom-Line Performance has passionately pursued a single goal: create the "right learning solution" for each client we serve. We are learning experts who are passionate, collaborative, and committed to helping our clients create the right learning solutions for their needs.
We are specialists in project management, multimedia, and technology design and development. Our award-winning learning solutions have helped corporate, non-profit, and government clients improve sales, reduce costs, reduce turnover, and retain customers.
Bottom-Line Performance is best known for excellence in blended learning design, curriculum design and development, game-based learning, and eLearning development. In addition to custom content development, BLP is widely regarded for its Knowledge Guru game engine, a platform used by corporate customers to quickly produce serious games.
Epic is a global provider of learning technologies, including custom e-learning, multi-device learning, mobile learning, platforms and learning consultancy. Epic has been developing workplace learning for a wide range of training needs since 1986. With clients from a wide range of sectors, including many Fortune 500 and FTSE 100 companies, Epic works with private, public and not-for-profit organizations to provide solutions that meet training requirements and save on costs, providing a great return on investment.
Epic is headquartered in Brighton, UK with offices in New York and Rio de Janeiro. Epic is part of Learning Technologies Group plc, a dynamic and steadily growing group of specialist learning technology businesses.
20 years ago Michael W. Allen and a handful of his colleagues set out on a mission to wipe-out boring online learning. Driven with a passion to create custom e-learning and blended learning solutions that focus on what the learner needs to do and not just know, we have been providing award-winning instructional services and products to assist hundreds of clients and thousands of learning professionals achieve this outcome.
Michael W. Allen, our CEO, has been a pioneer in the e-learning industry since 1975. He was the innovative force behind one of the most successful authoring tools ever created, Authorware, and recently launched ZebraZapps, a powerful authoring and publishing system. He's also widely known for his more than 40 years of insights and presentations about instructional design. He is the author of 8 books.
Designing Digitally, Inc. is an award-winning, full-service provider of interactive and engaging custom-built E-Learning, 3D Training Simulations, and Serious Games. We do more than just develop custom training solutions–we create strong relationships and work as a partnership to achieve your organization's learning objectives.
For over a decade, we've specialized in designing educational, engaging, and entertaining online learning and corporate training experiences tailored to fit your specific needs. We strive to provide a prosperous return on investment by producing high quality interactive learning solutions and immersive training.
Learnnovators specializes in the design and development of custom learning solutions for the workplace. We help organizations address skill and performance gaps in their workforce by creating tailor-made solutions that are aligned with their business goals.
We work as our clients' extended arm/thought-partner with a focus on maximizing results and return on investment. Whether it is choosing the best mode of learning techniques tailored to organizational objectives, or designing interactive modules with the help of games or simulations, we have implemented innumerable programs to the satisfaction of a worldwide clientele. These have been deployed on a variety of contexts and devices, including mobile phones, tablets, and interactive white boards. We have also crafted several just-in-time, micro-learning modules and performance-support solutions for our clients.
Since inception in 2003, we have successfully developed over 6000 hours of learning content for a wide range of domains including Advertising, Automotive, Banking, Defense, Engineering, Healthcare, Hospitality, HR Services, IT/ITES, Insurance, Manufacturing, Nuclear Energy, Oil and Gas, Retail, Safety, Soft Skills, and Telecom.
We also offer a simple, intuitive and mobile-ready learning platform, Learnosphere.
PulseLearning creates learning solutions that focus on maximizing business value. We achieve this by building a long term relationship built on mutual trust and a deep understanding of your business. We appreciate that what is important to our Clients can vary from project by project. For one project, an aggressive timeline may be the most critical measure of success; for another it may be pricing or the award winning creativity and innovation. Our Clients and Partners tell us that our global reach, and our understanding of key challenges in different markets, is a unique differentiator of tremendous value. Known for our creative spirit and imaginative product design, PulseLearning focuses on designing customized learning solutions for our Clients that make measurable, positive business impact.
Our learning solutions include: Custom eLearning, Blended Learning, Learning Management Systems, Localization, Staff Augmentation, Training Consultancy.
G-Cube is an award winning e-learning solutions provider that designs, develops and delivers technology-based learning solutions. Its solutions help organizations to improve their performance by using learning as a tool. Its learning solutions are broadly categorized into e-Learning Design, Courses Development and Learning Delivery Solutions.
G-Cube's services include custom content development, mobile learning solutions, content localization, game-based learning, simulations, ILTs and blended Learning solutions, and consulting for curriculum design. G-Cube's product portfolio includes the cutting edge WiZDOM Learning Suite comprising an LMS, Social Collaboration Tools, Virtual Classroom, Content Authoring Tool, Assessment Engine, and Skill-Gap & ILT management systems.
G-Cube has 250+ multi-skilled resources, including e-learning consultants, instructional designers, graphics designers, animators, illustrators and software engineers. G-Cube is CMMI Level 3 certified. With its focus on innovation and 'WoWing' the customer, G-Cube has won various industry awards, such as the Deloitte Tech Fast 50 India Award for the last five consecutive years, multiple Brandon Hall Awards for Excellence in Learning and Technology, the NASSCOM Emerge 50 Award, and multiple Apex Awards for Publication Excellence.
CCS Digital Education designs and creates custom e-learning and corporate e-training software applications for large organizations and learners worldwide.
We leverage evolving technologies in order to ensure continuous knowledge acquisition and effective skills retention with sustainable results. Through consultation we identify your unique needs and requirements and design highly customized solutions that address your challenges achieving measurable results.
CCS has extended experience in developing blended and mobile learning solutions to address knowledge and business performance challenges in different industries and regions of the world, addressing diversified language and cultural needs by developing highly innovative e-learning applications enriched with engaging learning features, interactive simulations and gamification elements.
Furthermore CCS provides a full range of value-added services, from quality assured content conversion and development services of learning and training materials to instructional design, storyboarding and full editorial reviews offering its clients turn-key solutions that improve efficiency and effectiveness while assuring the most competitive total cost of ownership.
CCS Digital Education (formerly CrystalClearSoft) is a privately held company with offices in Abu Dhabi, Athens, Moscow, Nicosia and Dublin.


Siduri Wines is looking for Harvest Seasonal Cellar Workers for the upcoming 2019 harvest season. We are a small winery, located in Santa Rosa, California, specializing in high-end Pinot Noir. Siduri sources premium fruit ranging from appellations like Santa Rita Hills and Santa Lucia highlands all the way up to Northern California's Anderson Valley, along with many vineyards from here in the Russian River Valley and Sonoma Coast region. We also work with small amounts of Zinfandel, Syrah, and Chardonnay. We are a tight-knit and efficient crew, and we're looking for people who enjoy working in a fast-paced, demanding environment, dealing with all aspects of the winemaking process.
Duties include sanitizing tools and equipment, sorting and processing grapes, punchdowns, pumpovers, winemaking additions, tank dig-outs, pressing, barrel downs, bulk transfers, and pretty much everything else in between. We expect applicants to be able to follow directions from the Winemaker and Cellarmaster, as well as written instructions. Applicants must be punctual and professional. Also, candidates should be detail-oriented, have a sense of urgency, and a positive attitude.
We generally work 10-hour days once harvest gets rolling with one set day off per week. The job generally lasts 10 - 12 weeks, starting in mid-August and running through November. Pay is competitive.
Last things: applicants need to be 21 years old at the time of employment, and need to be able to pass a drug test. Even though marijuana is legal in California now, our parent company, Jackson Family Wines, continues to adhere to Federal drug policy guidelines.
Send your resumé and a brief cover letter if you're interested.


Just got done setting up for my new show. If you are in San Francisco at all during the month of August stop down to City Arts Gallery in the Mission district. There is a show opening with all the artists on August 5, 2016 from 7 to 10, and there will be drinks, snacks, and fun people!


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Ryan Donk (Amszterdam, 1986. május 30. –) holland labdarúgó, 2016 óta a török Galatasaray SK játékosa.

Pályafutása

Klubcsapatban
Ryan Donk kívülállóként vett részt az RKC Waalwijk 2005–06-os szezonjában, és lejáró szerződéssel a zsebében úgy gondolta, magasabb szintre kell lépni. Először az AZ közelített felé, megelőzve ezzel az AFC Ajaxot, a PSV Eindhovent, sőt még a spanyol gigász FC Barcelona is érdeklődést mutatott. De Donk az AZ-t választotta, ahol a Hamburger SV-hez távozó védőt, Joris Mathijsent kellett helyettesítenie, úgy gondolta, ez a legjobb lehetőség a fejlődésére. A kezdetekkor az AZ egy szezonra vissza akarta kölcsönözni az RKC Waalwijknak, de Donk ezt nem akarta, úgy volt vele, ha nem játszik, legalább gyakorolhat a nagyszerű csatárokkal (Shota Arveladze, Danny Koevermans és Mousa Dembélé). Végül kiharcolta helyét a kezdőcsapatban, képességeivel lenyűgözte az AZ-t.

2008. augusztus 31-én Donk egy évre a West Bromwich Albion-hoz került kölcsönbe. 2008. szeptember 28-án a Middlesbrough elleni, idegenbeli 1–0-s siker alkalmával mutatkozott be.

A 23 éves korábbi holland U21-es Európa-bajnok labdarúgó a 2009–2010-es szezonban az AZ Alkmaar mezét a Jupiler League-es Club Brugge szerelésére cserélte 2009. június 26-án.

Válogatottban
2007-ben Donkot Foppe de Haan behívta a Jong Oranje a hazai rendezésű, Európa-bajnokságra készülő keretébe. Donk részt vett az első két meccsükön (Izrael, 1–0 és Portugália, 2–1), két győzelemmel bebiztosították az elődöntőbe jutást, és a 2008-as olimpián való részvételt. A torna alatt húga autóbalesetet szenvedett. Donk elhagyta a holland keretet egy napra, és azután tért vissza, hogy megbizonyosodott róla, hogy a hölgy jobban van. Miután biztossá vált az elődöntőbe jutás, Donk levette mezét, ami alatt az alábbi feliratú póló volt: "Dit toernooi is voor jou, ik hou van je." (Ez a torna neked szól! Szeretlek!), ezzel támogatva húgát. Az Anglia elleni elődöntőben (1–1, 13–12 32 büntetőrúgás után) Donk gólpasszt adott Maceo Rigtersnek, hogy ő a 90. percben megszerezze az egyenlítő gólt, ami ollózásból született, ezzel hosszabbításra mentve a meccset. Donk volt az egyetlen holland játékos, a pályán, akinek nem kellett büntetőt lőni, mivel az egyik angol játékos (Nedum Onuoha) megsérült, nem tudott lőni, Angliának pedig nem volt több cseréje. A hollandok megvédték 2006-ban elnyert címüket, miután a döntőben Szerbiát 4–1-re verték. A tornán való részvétel után Donkot behívták a holland keretbe, amit augusztus 6-án a www.nonstopshows.com-on jelentették be.

Játékstílusa
Játékstílusát gyakran Jaap Stam-hoz hasonlítják.

Jegyzetek

Fordítás

További információk
Ryan Donk profil a wba.co.uk-n
http://www.nonstopshows.com
mackolik.com profil (törökül)
Soccerbase profil

1986-ban született személyek
Labdarúgóhátvédek
Holland labdarúgók
Az AZ Alkmaar labdarúgói
Az RKC Waalwijk labdarúgói
A West Bromwich labdarúgói
Az FC Bruges labdarúgói
A Kasımpaşa labdarúgói
Élő személyek
A Galatasaray labdarúgói

redpajama_set_name: RedPajamaWikipedia


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Oak Hill High School Alumni Association – Robert C. & Birtie Massey Scholarship Fund
The very active Oak Hill/Collins High School Alumni Association has encouraged the formation of a number of scholarship funds that continue to benefit students in southern Fayette County. Robert and Birtie Massey were the parents of nine children who graduated from Oak Hill H.S. "I don't believe he had a child who could walk in his footsteps," commented Roy Massey of his father Robert Carter Massey. As a group, however, the living children of Robert and Birtie Bowman Massey have made an enormous footprint in the efforts of the Alumni Assoc. to build scholarship funds for current and future students. Their generous donations created an endowment in memory and loving honor of their parents who strongly believed that an education for their children was very important. Robert Massey wanted his children to have a life that was easier than his own. Additional donations were made in memory of the three deceased sons.
Current graduate or attended Oak Hill High School
Renewable: Yes; provided criteria is met.
Apply: May 1st Application Deadline - Confirm any changes on the Alumni Association's website
Contact Oak Hill High School guidance counselor for application materials or
Visit the Alumni website at http://www.oakhillreddevilalumni.org/


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Over 6 Years Later, Adele's '21' Drops From Billboard 200Despite the long run, it doesn't come close to Pink Floyd's "Dark Side of the Moon" for longevity.
4 Things To Know: Massive Flooding In La., Milwaukee Protests & MoreFrom historic flooding in the south to protests in Milwaukee, here are the four stories to know for Monday, Aug. 15.
Beyoncé And Adele Receive Emmy NominationsBeyoncé and Adele's new music are sure to earn multiple Grammy nominations, but before that they are celebrating with Emmy nominations.
Adele Mania Hits St. PaulThe Xcel Energy Center will be packed Tuesday night for a concert by one of the world's most famous vocalists. Adele is kicking off her first American tour in half a decade, and she is doing it in Minnesota.
Adele Teases 'Send My Love (To Your New Lover)' VideoThere will be dancing, apparently.
'Carpool Karaoke' Comes To Primetime Tonight With Jennifer LopezJames Corden brings "Carpool Karaoke" to primetime for a special.
Having A Hard Time Scoring Concert Tickets? Here Are A Few SecretsHave a hard time scoring seats to that in-demand concert you've been dying to see? You're not alone. Ticket insiders warn it's harder than ever to get concert tickets the old fashioned way. WCCO found the secret to snagging your favorite seats.
Adele, Kendrick Lamar, The Weeknd, Little Big Town Announced As GRAMMY PerformersThe 58th annual GRAMMYs have announced their first round of performers.
Adele Joins James Corden For Carpool KaraokeA very special passenger joined "Late Late Show" host James Corden for carpool karaoke Wednesday night.
Preview Adele's Carpool Karaoke With James CordenAdele is coming to "The Late Late Show with James Corden" on January 13th.
Taylor Swift, The Weeknd, Adele Have One Thing In Common: Tom CoyneHe's a behind-the-scenes guy who masters records after they are finished being recorded.
Adele Fans Experience Issues Getting Tickets For Xcel ShowsOne of the most popular artists in the music world right now, Adele will be performing two shows in St. Paul on July 5-6 to kick off her latest tour. Tickets went on sale at 10 a.m. on the Ticketmaster website, and they were hard to come by for many.
Adele To Perform 2 Shows In St. Paul This SummerAdele won't be saying "hello from the other side" of the ocean this summer! For the first time in five years, the world-renown singer is going to tour North America, and her first stop is St. Paul.
Southern University Marching Band Covers Adele's 'Hello'The hit song "Hello" from Adele is all over the radio and your playlists. It's also been used in countless ads and parodies. The album has already sold more than four million copies in less than two weeks.
Watch This Marching Band Cover Adele's 'Hello'!The Southern University Marching Band -- with help from the Dancing Dolls -- absolutely nails Adele's massive hit song!


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Keely Van Order (Canberra & Sydney)
The newest member of the Alpha CC team, Keely is an award winning artist with a foundation in drawing, painting and printmaking. She began her formal artistic training at the Australian National University where she graduated with a Masters of Visual Art in 2011, focusing on Digital Media. Since then she has worked as a course instructor across a range of subjects including traditional art mediums and creative software programs. She also works as a freelance graphic artist and will publish her first two major book projects with IFWG publishing this year, including a 75 page fully illustrated book with full creative direction of layouts and graphic design. Equally passionate about learning as she is teaching, Keely will also complete her third degree in Psychology this year.
Kyla Davies (Melbourne)
Kyla's creative background began in Fine Arts studying painting, illustration, printmaking and photography. These skills were the backdrop to starting a career in New Media and Digital Design in early 2000 where her versatility led her to specialising in designing for eLearning and interactive projects purposed for education of young children and adults. She became Art Director of a successful and award winning Melbourne based company and worked with companies such as Commonwealth Bank, Santos, CGU, Connex and IAG and other government and non-government organisations.
Her personal work has been more focussed on a providing a complete package from photography, logo/web design, marketing materials, design for social media and creative marketing strategies for charity and private sector as well as government.


I know it's not even December, but I've been thinking about Christmas since October. Not at all unusual for me, I'll admit, but this year, the fever hit early! And I know there are a lot of you out there who love Christmas as much as I do, but maybe you don't have as much time or interest to construct elaborate garlands out of real fir branches like I do. But fear not, spreading all the holiday spirit around your house can be easier than you think. Here are some super simple ways you can deck the halls this holiday season!
Every year, I always get some real tree trimmings to make Christmas decorations out of and this year, I decided to make a statement centrepiece for our pretty large dining table. This works just as well for a four-seat table, a round table, even a countertop, if that's where you eat most of the time! It's all about finding the right proportion for your size of table, and having an item that can kind of corral or anchor everything together, like a table runner or a tray, just so it doesn't look too chaotic.
But it's as easy as just laying down some branches along the middle of the table and placing various other decor pieces throughout the branches. I used acorns, candles, faux berries, faux holly and some super cute birds! Super easy.
Side note: The candles should be purely decorative unless they are fake, in holders that elevate them quite a bit, or in containers that keep the flame contained. DO NOT light candles when there are flammable things so close to the open flame!
Speaking of candles, nothing makes a holiday display more cozy and inviting! If you have some pillar candles, try displaying them on trays or in lanterns/jars, surrounded by various festive fixings. You can do acorns and pine cones, evergreen branches, berries, cinnamon sticks, you name it! Again, just be careful about lighting them if there are highly flammable objects in their close vicinity.
There are lots of great ways to use traditional tree ornaments everywhere other than on the tree! Basically any kind of surface that would support a hook or free-dangling ornament is fair game. I'm talking light fixtures, plants, curtain rods…if you take a walk around your house or apartment, I'll bet there are a few places that could accommodate some shiny baubles.
Side note: This may not work very well if you have a curious kitty or grabby toddlers. Which is why it's also super easy just to throw a bunch of ornaments in some kind of container or lantern. You can even add some string lights to make it extra magical. You still get a beautiful display of colour without having to worry that they'll end up broken or not where they are supposed to be!
So what are some of your favourite ways to decorate for the holidays?


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BAE Systems and Jaunt Air Mobility sign MoU for UAM vehicles
jsingsit 1 month ago
BAE Systems and Jaunt Air Mobility will collaborate on new product development for the future of aircraft electrification. Credit: Jaunt Air Mobility.
UK-based company BAE Systems and US-based electrical vertical take-off and landing developer Jaunt Air Mobility have signed a memorandum of understanding (MoU).
Under this agreement, the two parties will jointly develop electric energy management systems for urban air mobility (UAM) vehicles.
The companies will conduct research on products that could facilitate the future development of aircraft electrification.
The partnership will also jointly investigate the requirements of power management on aircraft and extending urban traffic into the airspace.
Jaunt Air Mobility chief executive officer Kaydon Stanzione said: "BAE Systems' development and integration expertise in high integrity controls and power management systems gives our business an edge in the development of next-generation air vehicles for urban environments."
The US start-up company has designed and developed a Reduced Rotor Operating Speed Aircraft (ROSA) solution for urban air mobility.
BAE Systems will bring more than 20 years of experience in developing and integrating electric propulsion systems to the partnership.
The company has installed over 10,000 electric-hybrid systems on transit buses and marine vessels in major cities, including Paris, London, New York, and San Francisco.
BAE Systems controls and avionics solutions vice-president and general manager Ehtisham Siddiqui said: "The collaboration with Jaunt Air Mobility leverages the strengths of two industry-leading companies to develop technology for a new ecosystem.
"This strategic collaboration builds on our two decades of heritage as we develop and certify controls and energy management systems for the future of flight."
Vision Systems Aeronautics is active in the design, testing, production...
Vision Systems Aeronautics is active in the design, testing, production and customer support of systems for business jets, helicopters, regional and commercial aircrafts.
TrooTrax gives you a full-time window into your mobile assets...
TrooTrax gives you a full-time window into your mobile assets and operations using self-customisable mapping, event triggers and data analytics that protect your bottom-line.
Rorosfly


His second Denon CD, "Second Look," featured "a terrific quartet, and sophisticated group interplay with a subtle, yet deeply rooted sense of swing." (Seattle Times, 1997). The music he created with John Abercrombie, Billy Hart, and Drew Gress was "like watching the wind blow over a lake; you can see the ripples but not the force behind it" (Seattle Post, 1996).
As critic Bill Milkowski described it, "Marc Copland delves into the harmonic fabric of a song the way Olympic gold medalist Greg Louganis dives into the swimming pool—with daring, grace and absolute trust in his instincts. He communes with the tune as if in a trance, inevitably coming up with a wholly fresh take on an old warhorse. 'To me, a tune is like a canvas and harmonies are colors. And I like to be free to put them on the canvas in a way that represents the way I see or hear a tune'" (Jazz Times, 1669).
In addition to his bandleading, Copland works as a sideman with Joe Lovano, Jane Ira Bloom, Tim Hagans, Ingrid Jensen, Ron McClure, and Ed Neumeister, among many others. A graduate of Columbia University, he lives in New York State. When not playing, composing, or teaching music to both professional musicians and small children, he spends his time with his "#1 son," five year old Darius James Copland.
Randy Brecker has been shaping the sound of jazz, R&B and rock for more than two decades. His trumpet and flugelhorn performances have graced hundreds of albums by a wide range of artists from James Taylor, Bruce Springsteen, Chaka Khan, George Benson and Parliament Funkadelics to David Sanborn, Horace Silver, Jaco Pastorius arid Frank Zappa.
Alter finishing high school. Randy attended Indiana University. In 1966, he moved to New York and one of his first gigs upon arriving was with Clark Terry's big band. Randy also began his foray into jazz-rock by helping to form Blood, Sweat and Tears. He worked with BS&T for a year and played on their innovative 1968 debut, Child is Father to the Man.
Randy left BS&T to join the Horace Silver Quintet. "BS&T was a very structured situation…I needed to stretch and play jazz." In 1968, Randy recorded his first album as a leader, Score (re-issued in 1993 on Blue Note), which also featured a 19 year-old Michael on tenor sax.
After Horace Silver, Randy joined forces with Art Blakey's Jazz Messengers before teaming up with brother Michael, Barry Rogers, Billy Cobham, and John Abercrombie to form the seminal fusion group Dreams. The group recorded two adventurous and wildly acclaimed albums – now collector's items – for Columbia Records before they disbanded in 1971.
In 1973, Randy was back with Horace Silver, teaming up with brother Michael as the front line in Horace's quintet. By now, the two horn players had become two of the most in-demand studio musicians of the day. The following year, the brothers joined Billy Cobham's group, and by 1975 they were ready to front their own band.
The Brecker Brothers were to become a band of immeasurable influence and impact. Hailed by pop and jazz critics alike, their first album, which Randy produced, was nominated for four Grammys. The Brecker Brothers went on to record a total of six albums and garner seven Grammy nominations between 1975 and 1981.
In the late 70s. Randy recorded on Charles Mingus' last album. Me Myself and Eye. Randy has performed with various incarnations of Mingus Dynasty Big Bands and Epitaphs up to the present day.
After the Brecker Brothers parted in 1982. Randy recorded and toured extensively with Jaco Pastorius, recording the famous Word of Mouth album, a live concert in Japan. It was soon thereafter that Randy met jazz pianist Eliane Elias. Eliane and Randy formed their own band. touring the world several times and recording one album together, Amanda for Passport Records. In 1986, Randy produced, arranged and recorded his first acoustic jazz album, In the Idiom, for Denon Records, with Al Foster. Ron Carter, Dave Kikosky and Joe Henderson.
In 1988, Randy recorded Live At Sweet Basil, a live album for Sonet Records at the famed jazz club Sweet Basil in New York with Bob Berg, Joey Baron and Dieter Ilg. Through the end of the 80s Randy toured North America and Europe several times as a leader, as well as touring with Stanley Clarke's Jazz Explosion. In 1989, he performed a sold out week at the Albert Hall In London with Eric Clapton.
The 1990s began with Randy on tour with the Mingus Dynasty/Epitaph. He also recorded and co-produced his third album as a leader. Toe To Toe, for MCA/Impulse in 1990. And in 1992, exactly ten years after they disbanded, Randy and Michael joined forces again in a much heralded reunion featuring a world tour and the triple-Grammy nominated GRP recording, The Return of the Brecker Brothers.
In the fall of 1994, the Brecker Brothers released the double-Grammy winning Out of the Loop, with tours that followed into 1995 throughout the U.S. and Europe. A tour highlight, they were the first international contemporary jazz group to perform in the People's Republic of China, playing to sell-out crowds in Beijing and Shanghai.
Branching out again in 1995, Randy toured Japan as a special guest with Stanley Turrentine and, as a leader, was one of the first Western jazz artists to tour for several weeks throughout Poland. Most significantly, he began recording his first solo album in six years with a band of musicians assembled from different parts of the globe, including long-time friend and musical cohort David Sanborn. guitarist Adam Rogers from Lost Tribe, Brazilian vocalist Maucha Adnet (singer with the late Jobim's band), and bassist Bakithi Kumalo of Graceland fame, among others.
In 1996, drawn to and inspired by the music of Brazil since his first visit there in 1979, Randy offered up his impression of Brazilian music mixed with pinches of Latin, world music, funk and Jazz on Into the Sun. Released first in Japan on Pony Canyon, it is available on Concord Records in the rest of the world and won Randy his first Grammy as a soloist in 1998 for "Best Contemporary Jazz Performance." A live concert of the music from the album was filmed by Japanese television station NHK and broadcast in 1997. Randy closed the year on tour with the Mingus Big Band across the U.S. and South America, and the Carnegie Hall Big Band in Europe. 1998 began with Randy's appearance on tour as a special guest with Billy Cobham in the U.K. In fact, it was while on stage in London with Billy that Randy first heard the news of his Grammy win. Summer appearances include several reunion concerts with Mark Whitfield and the 11th House as well as a special guest appearance with the Vanguard Orchestra in a Tribute to Thad Jones In Marciac, France. Randy is now planning the recording of a new solo effort.


text:
The Winnipeg Foundation announces 2021 distributions totaled a record-breaking $84.9 million to approximately 1,100 charities
This responsive and reliable community support is possible because of generous donors.
For immediate release – In a year when we have all been deeply affected by the pandemic, The Winnipeg Foundation is grateful to have been able to support the community with $84.9 million distributed to approximately 1,100 charities working in all Cause areas in our community. This is the most distributed, to the greatest number of charities, in The Foundation's 100-year history.
The Foundation's work is only possible because of generous donors. Despite living through the uncertainty of COVID-19, last year Manitobans yet again demonstrated why we are known as the most generous province. In 2021, The Foundation received a record 9,613 contributions totaling $189.8 million.
"The pandemic has impacted every aspect of our lives and the repercussions will be long lasting. However, we are never helpless. We can always rise to the challenges in our community," says Sky Bridges, CEO of The Winnipeg Foundation.
Charities deliver valuable programming that builds community and supports us all. The financial impacts of the pandemic have been especially challenging for charities, and so The Foundation is incredibly proud to have been able to deliver responsive and reliable support to our charitable sector. Between March 2020 and Sept. 30, 2021, The Foundation issued 749 COVID-related grants totaling $21,065,620.
During the pandemic, The Foundation's grantmaking adapted as circumstances evolved. It continued and heightened its practices of trust-based philanthropy, which includes engaging and listening to community organizations to understand their needs, being flexible with funding and reporting, and providing proactive and/or unrestricted funding. The Foundation also applied an equity lens to its work; acknowledging there are systemic barriers faced by Indigenous communities, Black communities, People of Colour, the 2SLGBTQ+ community and people with disabilities.
"The Foundation is a testimony to what we can achieve when we work together," says Doneta Brotchie, outgoing board chair of The Winnipeg Foundation. "2021 marked The Winnipeg Foundation's 100th birthday, and we are proud to be the first community foundation in Canada. We celebrated our centennial with a variety of collaborations and activities." Head to wpgfdn.org/celebrating-our-centennial for more.
While the ethos of service leadership is ingrained in The Winnipeg Foundation's approach to supporting community, it is being reflected on with new vigour as it enters its second century.
"The Foundation is working with stakeholders and the community to ensure we are helping to create a community where everyone has the opportunity to thrive," says Tom Bryk, incoming board chair of The Winnipeg Foundation. "We acknowledge this work requires an understanding of both power structures and of how institutions may inadvertently perpetuate inequities. We are committed to asking, listening and learning from our community as we build our best path forward. We also understand this requires reflection on both the individual and institutional level."
Gifts to The Foundation are pooled and invested in endowment funds, and a portion of the interest is granted back to the community each year. It is this endowment that allows The Foundation to provide responsive and reliable community support. The Foundation's endowment, which is made up of thousands of individual funds, totaled $1.748 billion at fiscal year-end 2021
To view The Foundation's audited financial statements, and read its 2021 Annual Highlights document, head to wpgfdn.org/publications
Please direct all media inquiries/questions to:


Home » blog » Welcome to 2015!
Happy New Year Everyone! I hope that 2015 will be a year full of happiness, good health and new adventures for you all!
I seem to have been quite busy at the end of 2014 and didn't manage to update my blog or my facebook page very often. I also haven't sent out any emails to my mailing list subscribers for some time either. I will endeavour to stay in touch better in 2015!


In our material library you find general information about our materials. The text about polycarbonate is currently only available in German. Please switch the language for more information. Do you already know which polycarbonate products you need? Follow the link below.


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Read Next:	Beyoncé Releases Music Video for 'Spirit,' Her 'Lion King' Soundtrack Contribution
April 8, 2014 11:55AM PT
Hilary Swank-Emmy Rossum Drama 'You're Not You' Gets U.S. Distribution
CREDIT: Jonathan Leibson/Getty Images
Entertainment One Films U.S. has acquired the North American distribution rights to indie drama "You're Not You," starring Hilary Swank, Emmy Rossum and Josh Duhamel.
The film will be released theatrically later this year.
"You're Not You" is produced by DPP in association with Di Novi Pictures (Alison Greenspan) and 2S Films (Molly Smith and Swank).
Cast also includes Loretta Devine, Ernie Hudson, Frances Fisher, Marcia Gay Harden, Ali Larter, Jason Ritter, Julian McMahon and Andrea Savage.
George C. Wolfe directed from a screenplay by Jordan Roberts and Shana Feste. The film is based on the novel of the same name by Michelle Wildgen.
Swank portrays a woman who has been immobilized by ALS, and Rossum plays an aimless and self-absorbed college student hired to be her caregiver in spite of her husband's objections.
The deal was negotiated for eOne Films by Sejin Croninger and for the filmmakers by CAA. Myriad Pictures is handling international sales and introduced the film to buyers at Berlin.


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Two million tons of oil will be produced at the Novy Port field already in 2016. New icebreakers needed to crack the the thick Arctic ice. Photo: Gazprom-Neft.ru
First icebreaker for new Arctic oil field
Gazprom Neft launches construction of the "Aleksandr Sannikov", one of two icebreakers for the Novy Port field in Yamal.
In a ceremony at the Vyborg Yard today, the keel was laid at the icebreaker of the type Aker Arc130A, the latest of Russia's new fleet of powerful Arctic vessels.
When handed over to Gazprom Neft in 2018, the ship will break ice in the shallow waters of the Ob Bay, opening the way for tankers shipping to and from Novy Port, the company's infrastructure hub at Cape Kamenny in the Ob Bay.
The icebreakers have been designed by the Finnish company Aker Yards, a press release from Gazprom Neft informs.
In the ceremony, Vyborg Yard director Kirll Voroshilov underlined that the new ship "is without analogues in the world", the yard writes.
The Novy Port project is Gazprom Neft's current biggest Arctic oil project. Already in 2016, the project will deliver two million tons of oil for exports. The shipments will be sent both westwards to EU markets and eastwards along the Northern Sea Route.
Part of the project is the laying of a 10,5 km long pipeline from the Yamal coast to an offshore terminal in the Ob Bay. That terminal will be linked with another 105 pipeline stretching towards the Novoportovskoye oil field in the peninsula.
The construction of Russia's new icebreaking vessels is all concentrated on yards located in and around St Petersburg. While the Baltiisky Yard is constructing the new generation nuclear-powered icebreakers, the Admiralty Yard and the Vyborg Yard produce diesel-engined vessels. Also the Yantar Yard in Kaliningrad has been involved in construction processes. In addition, the Russian-owned Arctech Yard in neighboring Finland is delivering icebreaking vessels for Russian stakeholders.
In addition to Gazprom Neft's Novy Port icebreakers, also company Novatek is in the process of building icebreakers for the Ob Bay. In April this year, Rosatom signed a contract with the Vyborg Yard on the construction of a 10MW icebreaker which is to accompany tankers to and from Sabetta, Novatek's LNG project in the area.
Icebreaker escort in Ob Bay. Photo: Gazprom-Neft.ru
Industry and Energy


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Post author:salman
Post category:Past Papers
921. When was the first ever email sent ?
C. 1971 *
922. The book " Indus saga and the making of pakistan " is written by __________.
A. Aitezaz Ahsan *
B. Prof. Ishtiaq Ahmad
C. Akbar.S. Ahmad
D. Mohsin
923. Which of the following prime ministers of india has received the award of Nishan-e- Pakistan ?
A. Pundit Jawaharial Nehru *
B. Moraji Desai (1990)
C. I.K. Gujral
D. None of these
924. Who wrote the book " Being and nonthingness" ?
A. Albert campus
B. Jean Paul satre *
C. Bertrand Russel
D. Rene Des
925. Jaundice is a disease in which the colour of the skin beccome:
A. Whitesht
B. Block spotted
C. Reddish
D. Yellowish *
926. Quaid-e-azam Muhammad Ali Jinnah swron in as the governor general of pakistan on _______
A. 14TH August 1947
B. 15Th August 1947 *
C. 8th August 1947
D. 17th August 1947.
927. Juvenile prisoners are under age of :
D. 16 *
928. The Current US presendient belongs to which party 2022?
A. Republication party
B. Democratic Party *
C. Independent
929. On which day of november of leap year the US Presidential elections are held?
A. Tuesday
B. Monday
C. Sunday *
930. Acid is naturalized by ?
A. Alkali
B. Salth
C. Chlorid
D. None *
Pages: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177


What we learned from experimenting with "smart" relevance ranking.
Handshake's mission is to democratize opportunity by making sure that every student, regardless of where they go to school or who they know, can find a meaningful career. At the core of Handshake's student product is a job search engine, where our 14 million students and young alumni can discover jobs from more than 300,000 employers.
Towards the end of last year, our data and platform teams decided to experiment with fundamentally different ways to power job search. Here, we'll discuss how we approached the problem, the service we built, and what we learned from the process.
As with typical search engines, we index our documents, which are job postings in our case. The documents are stored in an inverted index, which allows for quick, full-text search. An inverted index maps all the unique tokens in a document to a list of the documents in which they each appear. We store our indexed documents in Elasticsearch.
When a user types in a query, we break down that query into tokens and look up the tokens in the inverted index. After stemming and removing stopwords, we use numerous strategies to look up the tokens in the inverted index, including partial-word and fuzzy word matching. Finally, the search engine ranks the job postings and returns the results.
To rank the postings, we use Elasticsearch's tf-idf scores; however, we've also tried to improve this ranking using other things we know about students. For example, when a student creates an account on Handshake, we ask them to select their preferred industries, locations, and job roles or occupations,. We then boost the scores of the postings that match their preferences.
Learning to rank (LTR) is the application of machine learning to relevance ranking. LTR is typically used as a reranking layer on top of an existing search engine, which means that after the search engine returns the top x documents, the LTR service simply reranks those x documents before returning the results.
This architecture is preferred over replacing the whole search engine with the machine learning model for two reasons. First, traditional search engines are typically good enough at returning a set of relevant documents (measured by recall and precision ). Our goal is to improve how the documents are ranked. We do not need to train a machine learning model to do both tasks, so we use LTR to specifically improve relevancy ranking. The second reason for using LTR as an additional layer is for performance; reranking 500 or 1000 postings is much quicker than reranking tens of thousands of postings.
We considered two different implementations of LTR: using the Elasticsearch LTR plugin and creating our own service using Ranklib (the library of reranking algorithms that the Elasticsearch LTR plugin is built on). We decided to go with the latter option, as it would not make us dependent on a specific version of Elasticsearch and allows for more configurability.
4 — applied to the job.
Using the users' behavior theoretically allows the model to find latent patterns that we would not be able to detect. The features are characteristics of the jobs or employers and the user — like whether or not the employer belongs to the user's preferred industry, or whether or not the employer is hiring students from the user's school year. We used this training set to train models using each of Ranklib's eight reranking algorithm implementations, settling on LambdaMART for the MVP reranking service as it had the best [email protected] score.
With our trained model, we set out to make a service we could use as the reranking layer of our search architecture. The original idea was to write a Go service that would execute the Ranklib bash command for every search. However, we realized how inefficient this would be as every request would require a jvm be spun up to execute the Ranklib jar.
To solve this problem, we decided to write a Java service. Not only did this help with efficiency, but it also allowed us to make some customizations allowing for easier integration with our main app. For example, writing our own API instead of using Ranklib's rerank method allowed us to pass a JSON object of jobs to rerank, instead of a file in QID format.
Search architecture with reranking service.
The best way to know if our reranking service performed better than only using Elasticsearch would be to deploy it to production and see if more students were clicking on and applying to jobs. We are currently evaluating productionizing this service and comparing it against newer options that we believe could perform better (more to come on that later!).
It's important to note that machine learning does not solve everything. And while using machine learning to solve relevance ranking sounds great, there are many other low-investment ways to improve how we show jobs to students. For example, we can make sure that we are collecting more accurate and up-to-date preferences from students so we can use our current framework to show them the best jobs possible. Or we could empower users to make better searches, and therefore find better results, by providing more helpful search keyword recommendations.
One of the biggest takeaways from this project, which will help inform the future of search at Handshake, is that many students are still in an exploratory mode. They are unsure of what they are looking for, or, at the very least, are unsure of how to translate their goals into search keywords. In fact, 59% of searches use no keywords, relying on filters and our job ranking. Handshake is uniquely positioned to help these users as we focus exclusively on early talent. In the coming months, we will be rethinking how we approach job search to determine the best way to help all of our users find and build meaningful careers.
If you have thoughts on any of the topics discussed here, feel free to reach out (@samhitakarnati on Twitter)!


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Q: Filtering the output from Table and export it into excel I have the following functions
f1[c1_,c2_,p1_,n_,i_]:= Sum[
    Binomial[n,j]  p1^j (1-p1)^(n-j),
        {j,0,c1}] + Sum[
    Binomial[n,k] p1^k (1-p1)^(n-k+n i),
        {k,c1+1,c2}]

and
f2[c1_,c2_,p2_,n_,i_]:=Sum[
    Binomial[n,j] p2^j (1-p2)^(n-j),
        {j,0,c1}] + Sum[
    Binomial[n,k] p2^k (1-p2)^(n-k+n i),
        {k,c1+1,c2}]

(actually the functions are identical. Both are kept for "historical" reasons)
From the output of
Table[Table[Table[{f1[c1, c2, 0.01, n, 5], f2[c1, c2, 0.05, n, 5]}, {c2,
    c1 + 1, 6, 1}], {c1, 0, 4, 1}], {n, 175, 185}]

I need only such values which satisfy $f_1\geq 0.95$ and $f_2\leq0.05$ with there parameters (value of $c_1$,$c_2$ and $n$). And how to export this output in excel.

A: You can generate a full Table of values as you stated
myTable = Table[
  {c1, c2, n, f1[c1, c2, 0.01, n, 5], f2[c1, c2, 0.05, n, 5]},
  {c1, 0, 4, 1},
  {c2, c1 + 1, 6, 1},
  {n, 175, 185}
  ];

Then make a selection of the values you wish using Select, Partition and Flatten
mySelection = Select[
  Partition[Flatten[myTable], 5],
  #[[4]] >= 0.95 && #[[5]] <= 10^17 &
  ]

Note that I changed the bound for the f2 function here as it seems to produce very different values than your original limits seemed to anticipate.
Finally Export the result to Excel
Export["~/Desktop/mySelect.xlsx", mySelection]

You will have to change the path for your OS if it's not Unix-based.

A: First of all I think that one function definition is ok:
f[c1_,c2_,p_,n_,i_]:= Sum[
    Binomial[n,j]  p^j (1-p)^(n-j),
        {j,0,c1}] + Sum[
    Binomial[n,j] p^j (1-p)^(n-j+n i),
        {j,c1+1,c2}]

Then use the k_v's answer in the form
t=Flatten[
    Table[
        If[(a=f[c1, c2, 0.01, n, 5])≥0.95 && (b=f[c1, c2, 0.05, n, 5])≤0.05,
        {c1,c2,n,a,b}],
    {c1, 0, 4, 1}, {c2, c1 + 1, 6, 1}, {n, 175, 185}
    ]/.Null->Sequence[]/.{}-> Sequence[],
2]

as it seems that you want to keep track of the input parameters as well. Flattening provides a single list of parameter-solution vectors, which one exports again as said by k_v using
Export["myFile.xls",t]

A: firs of all there's no need to use nested Table, and you may use values selection directly inside the table evaluation
t=Table[
If[f1[c1, c2, 0.01, n, 5]≥0.95 && f2[c1, c2, 0.05, n, 5]≤0.05,
{f1[c1, c2, 0.01, n, 5], f2[c1, c2, 0.05, n, 5]}],
{c1, 0, 4, 1}, {c2, c1 + 1, 6, 1}, {n, 175, 185}]/.Null->Sequence[]/.{}-> Sequence[]

this way let not to brake the structure of output
to export - Export["table.xls",t]

redpajama_set_name: RedPajamaStackExchange