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Contralateral Breast Cancer Risk Is Highly Overestimated
By Caroline Helwick
When they see the risk, compared to the small benefit, patients start to change their decisions.
— Courtney Vito, MD
Breast cancer is highly unlikely to develop in the contralateral breast of women treated for primary breast cancer, yet many women continue to fear it and undergo prophylactic mastectomies.
"Regardless, the perceived risk of developing and dying from a contralateral breast cancer is highly overestimated, and this has been shown to be a driving force for aggressive surgical intervention," said Lori Uyeno, MD, MPH. Dr. Uyeno and colleagues documented the incidence of contralateral breast cancer and its impact on overall survival after mastectomy for unilateral breast cancer. They presented their findings at the 2012 Breast Cancer Symposium.1
While contralateral breast cancer is the most common malignancy among breast cancer survivors, it is still incredibly rare. The risk figure usually quoted is 0.5% to 1.0% per year, said senior author Courtney Vito, MD. "But our study found the risk to be less than 1% at 51 months, and this is a very big difference," she noted. Previous estimates may be higher because they originated during an era of less effective systemic therapies.
"We also found that when a contralateral breast cancer does occur, the only patients with a decrease in overall survival are those with a late-stage presentation (stage IIB/III/IV)," Dr. Vito added.
SEER Database Explored
Investigators used the Surveillance, Epidemiology and End Results (SEER) database of 109,411 women (median age, 54 years) with a primary diagnosis of unilateral breast cancer between 1998 and 2006. Patients underwent mastectomy, and about 10% also had a contralateral prophylactic mastectomy. The median follow-up was 51 months beyond the 1-year survival landmark.
The researchers divided the population into two similar groups: a test sample (n = 54,706) and a validation sample (n = 54,705). The patients' primary tumors were mostly early stage (1–IIA, 63%), moderately or poorly differentiated (78%), and hormone receptor–positive (52%).
Low Incidence of Contralateral Cancer
After 51 months' follow-up, contralateral breast cancer was diagnosed in 867 women (0.79%) at a median age of 61 years after a median observation time of about 2 years. The majority of these (66.2%) were detected at an early stage (0–IIA) and were moderately/poorly differentiated and estrogen receptor–positive.
The analysis showed a stage-specific effect on overall survival. "Only contralateral tumors that were stage IIB to IV increased mortality. Early-stage contralateral breast cancer had no effect on overall survival," Dr. Uyeno reported.
The survival analysis was adjusted for primary tumor characteristics and treatment (including contralateral prophylactic mastectomy), patient demographics, and aging.
The adjusted hazard ratios were 3.04 for stage IIB/III/IV on the test sample (P < .0001) and 2.72 (P < .0001) on the validation sample. Stage I/I/IIA and tumors of unknown stage carried hazard ratios of 0.73 (P = .05) and 1.20 (P = 0.21), respectively.
Factors Linked to
Later-stage Tumors
"We then wanted to know which patients are most at risk. This is not information we generally have when we see the patient upfront and are making decisions about treatment," Dr. Vito said.
The 247 cases of stage IIB/III/IV contralateral tumors were compared with 559 cases of stage 0/I/IIA tumors. The likelihood of having an advanced-stage contralateral tumor was greater when the patient's original tumor was aggressive (extensive disease, large size, positive nodes) and when the patient was African American. Although African-American race is a risk factor nationwide (twofold risk compared to other races), it was much greater for patients living in the Southeast (sixfold risk compared to other races), which the investigators attributed to the possibility of reduced access to health care or cultural biases. Shorter time since the primary diagnosis was also associated with having a contralateral tumor of an advanced stage.
Efforts to improve survival after unilateral breast cancer should emphasize early detection of contralateral breast cancer, the researchers advised. Intensive monitoring should begin early after treatment of the primary tumor, and any barriers to follow-up should be addressed.
Dr. Vito said she counsels patients by "giving them the true numbers," which come as a surprise to many women, she said. She also informs them that their risk for a surgical complication is at least 20%, for prophylactic mastectomy with reconstruction, according to series from Mayo Clinic and The University of Texas MD Anderson Cancer Center.
"When they see the risk, compared to the small benefit, patients start to change their decisions," she said.
Cornelia Liedtke, MD, of the University of Muenster, Germany, commented on the study. "Patients tend to opt for more safe therapies because of their anxiety, but several analyses of contralateral breast cancer risk show that risk is only really increased in families with known mutations. I advise against prophylactic mastectomies unless the patient has a proven mutation," she told The ASCO Post. ■
Disclosure: Drs. Uyeno, Vito, and Liedtke reported no potential conflicts of interest.
1. Uyeno L, Behrendt, Vito C: Contralateral breast cancer: Impact on survival after unilateral breast cancer is stage-dependent. 2012 Breast Cancer Symposium. Abstract 69. Presented September 14, 2012.
Upgrading of Nonmelanoma Skin Cancers at the Time of Mohs Surgery
Poorer Outcomes for Patients With Lung Cancer Undergoing Radiotherapy During Disaster-Level Hurricanes
Maintenance Panitumumab vs Panitumumab/Fluorouracil/Leucovorin in RAS Wild-Type Metastatic Colorectal Cancer
ReDOS: Regorafenib Dose-Escalation Strategy in Refractory Advanced Colorectal Cancer
CLEOPATRA End-of-Study Analysis in Metastatic Breast Cancer: 37% Alive at 8 Years
Combination Immunotherapy and Inhibitors of DNA Damage Repair in the Treatment of Small Cell Lung Cancer
James L. Mohler, MD, on Managing Prostate Cancer: NCCN Guidelines Updates
Sara A. Hurvitz, MD, on HR+/HER2− Advanced Breast Cancer: MONALEESA-7 Trial on Endocrine Therapy With or Without Ribociclib
Hope S. Rugo, MD, and Matteo Lambertini, MD, PhD, on the SOPHIA Trial in HER2-Positive Metastatic Breast Cancer: Chemotherapy Plus Margetuximab vs Trastuzumab
Sagar Lonial, MD, on Multiple Myeloma: Sequencing Therapies
Josep Tabernero, MD, PhD, on Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: Pembrolizumab With or Without Chemotherapy vs Chemotherapy


I am making a origami Yoda mini series! If you want to be in send an audition to grantthetimelord@gmail.com you can audition for every character!
i will email you if you make it! The audition must be a video, if you make it I will send you scripts. I am almost done writing season 1. It will be epic! I hope you audition and make it!


text:
import Ember from 'ember';
import InternalSession from '../internal-session';
import Ephemeral from '../session-stores/ephemeral';

export default function setupSession(registry) {
  registry.register('session:main', InternalSession);

  if (Ember.testing) {
    registry.register('session-store:test', Ephemeral);
  }
}

redpajama_set_name: RedPajamaGithub


text:
12 Sets of Resources for Aspiring Public Theologians
January 14, 2019 No Comments	Politics and Public Life Bruce Ashford
One of the pleasant surprises that has arisen from the political turmoil our nation experiences is a spike in the number of young Christians who take an interest in public theology. They may not always use the phrase "public theology," but they are asking intelligent questions about issues at the intersection of Christianity, politics, and public life. Often, these embryonic public theologues ask for recommended reading.
In light of the growing interest in this area of study, I offer in this post a dozen sets of resource that I often recommend to budding public theologians. I've included a variety of resources, some of which represent views I oppose. However, the majority of the resources fit my preferred "Reformational" model. And, for the most part, I've limited myself to books I've read cover to cover.
As a brief preface, I should mention that "public theology" is similar to "political theology," but by these two academic subdisciplines are not synonymous. They are similar in that both disciplines arose in reaction to secularism and sectarianism, and both disciplines speak theologically about political realities. But they are different in that political theologians focus primarily on the political sphere, whereas public theologians tend to focus on society's total architecture—including not only politics, but also the arts and sciences, scholarship and education, marriage and family, sports and competition, and business and entrepreneurship.
1. Surveying Different Views of Christianity and Culture
Richard Niebuhr's Christ and Culture is a minor classic in 20th century theology; it provides a historical classification of typical Christian views of the relationship between "Christ" and culture. In combination with Niebuhr's book, you'll want to read D. A. Carson's Christ and Culture Revisited and Craig Carter's Rethinking Christ and Culture. Carson critiques Niebuhr's theological framework and argues for a more cruciform understanding of the Christian's place in culture. Carter also critiques Niebuhr's theological framework as well as Niebuhr's privileging of Christendom in the conception of his categories. James K. A. Smith's brief article critiques Carson from a Reformational point of view. In this video and this article, I summarize and critique five historic views of grace and nature (Christianity and culture).
2. Introducing a Reformational View of Christianity and Culture
Al Wolters' Creation Regained is an extraordinarily lucid conceptualization of the Reformational worldview; it can be employed easily for a preacher or professor who wishes to provide the undergirding for a Reformational understanding of culture. Goheen and Bartholomew's Living at the Crossroads is a worldview text that also functions as a fine introduction to Reformational public theology.
When cultivating a genuinely Reformational view of Christianity and culture, we should take care to emphasize the head and the heart. Abraham Kuyper's Lectures on Calvinism is a slim but powerful volume arguing that Reformational Christianity provides a sturdier worldview than modernism, and showing some ways that Christian convictions should shape our approach to various spheres of culture: religion, politics, science, and art. James K. A. Smith's Desiring the Kingdom goes beyond Kuyper's worldview approach to show how and why human beings are "lovers" and not merely "thinkers." Although Smith's book criticizes the shape of certain Kuyperian approaches, it is best understood as an insider's attempt to help make the Kuyperian tradition healthier.
3. Understanding our Secular Context
If we want to bring the West into an effective encounter with the Christian gospel and its ensuing worldview, we must engage in both biblical and cultural exegesis. And, in a Western context, that entails an exegesis of our secular age. (Note: the books I recommend in this section make quite a demand on the reader.)
First, I recommend Jewish-American sociologist Philip Rieff's My Life among the Deathworks, a prescient analysis and evaluation of the West's attempt to sever society and culture from the influence of religion (for a concise summary and evaluation of Rieff, here is my "A Theological Sickness unto Death: Philip Rieff's Prophetic Analysis of our Secular Age"). Second, Canadian philosopher Charles Taylor's A Secular Age. Like Rieff, Taylor provides an evaluation of the rise and development of our secular age, the most helpful aspect of which is his description of what it feels like, existentially, to live in such an age. (For a brief summary and evaluation of Taylor, here is my "Tayloring Politics for a Secular Age." For a summary of Taylor's thought, see James K. A. Smith's How (Not) to Be Secular.)
I also recommend literary critic George Steiner's Real Presences and Grammars of Creation, which argue that modernity has broken the "covenant" between word and world, engendering skepticism and irony while subverting meaning, morality, and creativity; Italian political philosopher Augusto Del Noce's The Crisis of Modernity and The Age of Secularization, which make the case that the modern west is now an "opulent society" that has rejected Christianity for the twin ideologies of scientism and eroticism; Australian sociologist John Carroll's The Wreck of Western Culture, which argues that secular humanism has made our culture into a "colossal wreck," divesting life and death of their divine meaning, thereby undercutting the moral order and ruining our social fabric; and public theologian Richard John Neuhaus' American Babylon. Neuhaus argues that the relativism of American universities has radically reshaped American society and culture, and for the worse.
4. Understanding the African-American Experience
The institution of slavery was like an environmental disaster on the moral ecology of our country, the negative effects of which continue to haunt our nation. Any public theologian worth his salt will make is a priority to read on regularly about racial justice and the African American experience.
For theological reflections on the Civil Rights Movement, James M. Washington's A Testament of Hope invaluable as an edited collection of MLK's sermons, speeches, essays, interviews, and autobiographical reflections. Through these, we are able to "hear" what MLK had to say about race, racism, nonviolence, social policy, integration, black nationalism, and the ethics of love and hope. Also, it would be beneficial to read Howard Thurman's Jesus and the Disinherited, given Thurman's influence on MLK.
For contemporary treatises on racial reconciliation, see John Perkins' Let Justice Roll Down and One Blood, both of which are among the best books I've read this decade. John Perkins should be recognized as a national hero for his work in racial reconciliation and community development. For more resources from John Perkins, click here. Don't miss Carl Ellis Jr.'s
Free at Last? The Gospel in the African-American Experience; although Ellis wrote this book for African-American Christians, it is also a very helpful resource for white Christians because it helps us understand African-American history and culture from the perspective of a respected black leader and theologian. For more resources from Dr. Ellis and his wife, Dr. Karen Ellis, click here. Finally, check out George Yancey's Beyond Racial Gridlock, a very helpful and accessible book that defines racism, evaluated four secular theories for overcoming racism, and provides a distinctively Christian way of defining and overcoming racism.
5. Making Culture and Stewarding Culture
Andy Crouch's Culture Making is an engaging and persuasive treatise on the Christian community's calling to "make culture" rather than merely "engage the culture." James Davison Hunter's To Change the World argues that Christian strategies for "changing the world" are doomed from the start, because they fail to recognize the role of the cultural elite in fostering such change. I pair these two books not only because they cover some of the same terrain, but also because Hunter criticizes Crouch's book. After reading the two books, including Hunter's criticisms of Crouch, you'll want to read Crouch's two fine replies here and here. Makoto Fujimura's Culture Care argues that culture is "not a territory to be won or lost but a resource we are called to steward with care."
6. Reading from the Major Ecclesiastical Traditions
The most important historic resource for an aspiring public theologian is Augustine's City of God, in which we observe a masterful public theologian bearing witness to the gospel in the midst of a declining empire. I recommend either the Modern Library edition or the abridged version with a foreword by Vernon J. Bourke. Many public theologians—from vastly different ecclesial traditions—draw upon Augustine and even seek to locate themselves within a broadly Augustinian framework.
Also important is exposure to exemplary work of public theology or political theology from some of the major ecclesiastical traditions. For starters, I recommend Jacque Maritain's Man and the State (Catholic), John Howard Yoder's The Politics of Jesus (Anabaptist), Robert Benne's The Paradoxical Vision (Lutheran), Oliver O'Donovan's The Desire of the Nations (Reformed Anglican), and Jonathan Leeman's Political Church (Baptist).
7. Building a Public Theology in the Kuyperian Tradition
My second recommendation is to learn as much from Abraham Kuyper as you can. In terms of primary resources, I recommend starting with Lectures on Calvinism and the Kuyper Centennial Reader before going on to read the Abraham Kuyper Collected Works in Public Theology (12 vols.), especially Our Program: A Christian Political Manifesto. In terms of secondary resources, I recommend Richard Mouw, Abraham Kuyper: A Short and Personal Introduction (compact and accessible); James Bratt, Abraham Kuyper: Modern Calvinist, Christian Democrat (a scholarly but accessible biography); Craig Bartholomew, Contours of the Kuyperian Tradition: A Systematic Introduction (the gold standard commentary on Kuyper and the Kuyperian tradition); Luis Lugo, ed. Religion, Pluralism, and Public Life (essays mining Kuyper's legacy in order to "put it to work" in the twenty-first century); and John Bolt, A Free Church, A Holy Nation (an exposition of Kuyper's public theology in conversation with contemporary issues and debates).
My third recommendation is to read some contemporary works of public theology in the line of Kuyper. I recommend David Koyzis, Political Visions & Illusions (the gold standard work in Kuyperian political science, critiquing the idols that undergird modern political ideologies such as liberalism, socialism, nationalism, and conservatism); Richard Mouw and Sanders Griffioen, Pluralisms and Horizons (a fine little volume addressing the problem of Christian faithfulness in a plural society); James Skillen, The Good of Politics (a concise introduction to politics from a biblical, historical, and contemporary perspective); Jonathan Chaplin, Talking God (arguing for the validity of religious public reasoning); James K. A. Smith, Awaiting the King (from within the Kuyperian tradition, Smith draws heavily upon Augustine and O'Donovan to offer a contemporary Reformational public theology); and, finally, my contribution to this discussion in One Nation under God, a small and accessible introductory textbook for undergraduate students.
8. Promoting a Christian View of Gender and Sexuality in our Secular Age
Gender and sexuality are disputed and contentious topics in our secular age. I recommend starting with Daniel Heimbach, True Sexual Morality (a comprehensive evangelical argument against the pagan sexual ethic that pervades our era); Russell Moore and Andrew Walker, The Gospel & Same-Sex Marriage (a biblical evaluation of the same-sex marriage movement); Sherif Girgis, Ryan T. Anderson, and Robert P. George, What is Marriage? (a natural law evaluation of the same-sex marriage movement); Rosario Butterfield, The Secret Thoughts of an Unlikely Convert (a wonderful memoir written by Butterfield, formerly a radical feminist, lesbian, tenured professor of English who now is an evangelical Christian writer married to a Presbyterian pastor); Andrew Walker, God and the Transgender Debate (a biblical evaluation of gender dysphoria and transgenderism); and Ryan T. Anderson, When Harry Became Sally (a natural law evaluation of gender dysphoria and transgenderism).
9. Promoting a Christian View of Life and Death in our Secular Age
As John Paul II noted in Evangelium Vitae, the West is now enveloped in a "culture of death." Any public theologian worth her salt must be able to make the case for human dignity and a culture of life. I recommend Daniel Darling, The Dignity Revolution (a compact treatment of human dignity, showing its application to a variety of contemporary social and political debates); Richard John Neuhaus, "We Shall Not Weary, We Shall Not Rest," (Neuhaus was an extraordinary man and compelling writer, and this pro-life essay is him at his best); Robert P. George and Christopher Tollefsen, Embryo: A Defense of Human Life (a scientific and philosophical case that the fetus is a human being from the moment it is conceived); Francis J. Beckwith, Defending Life: A Moral and Legal Case against Abortion Choice (probably the best systematic philosophical and legal treatment of the pro-life position.
10. Bringing the West into an Encounter with the Gospel—via Politics and Public Life
Upon returning to the U.K. after three decades as an Anglican missionary to India, Lesslie Newbigin devoted his life to helping bring the West into a "missionary encounter" with the gospel. I recommend Newbigin's Foolishness to the Greeks, in which he explains what it will take to bring the secularized West into a genuine encounter with the gospel, and Truth to Tell, in which he argues that the gospel is a public truth in the light of which all other modes of thought should be evaluated. In a similar vein, Heath Thomas and I recently wrote a book, The Gospel of our King, that expounds the Christian gospel and applies it to our social, cultural, and political life in this world. Finally, "Powerful Witness from a Position of Weakness," an essay I wrote about political witness in a secular age.
11. Cultivating a Christian Disposition
One of the most difficult things to do in our dysfunctional, vitriolic, and effluvial public square is to maintain a genuinely Christian disposition—one that combines truth and grace. Toward that end, I recommend Richard Mouw, Uncommon Decency, which calls for the cultivation of Christian civility in an uncivil world; Os Guinness, Fool's Talk, which appeals to Christians to recover the lost art of persuasion; Tim Keller, The Reason for God and Making Sense of God, allows the reader to see one of our era's finest apologists in action, combining truth and grace to make the case for Christianity in a secular age; Russell Moore's Onward, which is a warm-hearted and compelling call for Christians to engage the culture without losing the gospel; and last, but by no means least, Rosario Butterfield, The Gospel Comes with a House Key, which is a stirring call for Christians in a secular age to tear down walls by opening our homes to our secular neighbors.
12. Studying to become a Public Theologian
If you're serious about studying public theology, I invite you to come study with me and my colleagues at The College at Southeastern and Southeastern Baptist Theological Seminary.
For undergraduate students, I recommend especially one of the following three courses of study:
Bachelor of Arts in Philosophy, Politics and Economics
Bachelor of Arts in Justice and Social Ethics
Bachelor of Arts in Humanities
For graduate students, I recommend:
Master of Arts in Ethics, Theology, and Culture
Master of Divinity in Christian Ethics
For doctoral students, I recommend:
PhD in Theological Studies with a Concentration in Public Theology
Christianity and politics
Bruce Ashford
Dr. Bruce Ashford serves as Provost and Professor of Theology & Culture at Southeastern Baptist Theological Seminary. He is also the author of Every Square Inch: An Introduction to Cultural Engagement for Christians and One Nation Under God: A Christian Hope for American Politics.
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redpajama_set_name: RedPajamaCommonCrawl


Over the next 4 days we'll be at Star Wars Celebration Anaheim and we'll be updating and posting fun stuff on all of our Facebook, Twitter and Instagram pages throughout the convention.
We're also going to try and do updates here for you all to get caught up on all of the days activities. Below is our general schedule but if there is anything specific you'd like us to check out be sure to check out the Star Wars Celebration website and let us know.
If you will be at Celebration, feel free to join us at any of these events. Just send us a message or email.
Beginning Thursday Morning, there will be a live-stream of Star Wars Celebration beginning with the opening panel with J.J. Abrams and Producer Kathleen Kennedy.
Be sure to check out the live-stream here, and we've learned that any information or trailers will NOT be blacked out for those online.
Below is our tentative schedule for the 4 days of the Convention. If you see us around, please feel free to say hi and join us for some Star Wars fun. This is obviously in addition to all of the great stuff on the show floor.
Keep in mind, this schedule is only tentative, things are obviously subject to change due to other factors.
Don't miss the big kickoff for Star Wars Celebration Anaheim. Star Wars: The Force AwakensWriter/Director/Producer J.J. Abrams and Producer Kathleen Kennedy will be on the Celebration Stage, joined by special guests.
Take a deeper look at the iconic music of Star Wars as David Collins reveals story connections and hidden musical secrets within John Williams' iconic film scores. And for the first time ever, watch scenes from The Empire Strikes Back with the original music restored!
Be among the first to get a sneak peek into what new exclusives will be coming from the Disney Parks in 2015 & 2016. You will also take an inside look behind the magic at how Disney Parks creates exclusive Star Wars merchandise, with insights from Disney's creative development team. With Brad Schoenberg, Cody Hampton, and Quynh Kimball.
Who will win in the battle of Light Side vs. Dark Side? Live game show with some of your favorite Star Wars and pop culture personalities.
Join the talented team from DICE as they give fans their first look at Star Wars Battlefront and debut the official reveal trailer for this highly anticipated game. Learn how unprecedented access to the Lucasfilm archives and the award-winning Frostbite technology is helping to create an immersive experience that is truly "most impressive". DICE will also show fans how Star Wars Battlefront will give them the chance to live out their epic Star Wars battle fantasies.
Fresh from the set of Star Wars: The Force Awakens, Carrie Fisher talks about her life in the entertainment industry, her history in the Star Wars saga, and just about everything else that comes to mind.
Anthony Daniels, the one actor to appear in all seven movies thus far, will be on stage to present a unique hour of entertainment. Expect the unexpected when the man behind C-3PO takes the stage.
Lucasfilm's visual effects division, Industrial Light & Magic, is celebrating an anniversary this year. John Knoll, Chief Creative Officer and Sr. Visual Effect Supervisor, as well as Visual Effects Supervisor for the Star Wars prequels, presents.
Smuggler's Bounty reteams the creatives behind the Celebration VI hit Star Wars: Smuggler's Gambit. Directed by Kyle Newman and co-written by Newman and F.J. DeSanto, Smuggler's Bounty stars Han Solo and is set during the events of the original trilogy. This one-time-only live performance will be presented with music and live sound effects. Smuggler's Bounty will feature hosts from all three Celebration stages, as well as a star-studded crew of performers to bring this great Celebration exclusive to life!
James Arnold Taylor's kicks off the evening with his critically-acclaimed one-man show, that takes the audience on a fast-paced, multimedia ride through the life of a voice actor. In the production Taylor performs more than 200 different voices live. The Main Event of this unforgettable evening, spend an hour with Mark Hamill. An actor with a rich acting and voice acting career, Hamill is known best to Star Wars fans for bringing the iconic character of Luke Skywalker to life in the Star Wars saga. There will be one seating for the two shows, and a 15-minute intermission in between. If additional seating is available for Mark Hamill, those seats will be filled in during intermission.
Our favorite Star Wars baron administrator takes to the stage for an hour of talk about his life in and out of Cloud City.
As we get ready for our big Star Wars Celebration week, we'll be sharing some cool things we are being sent from vendors and others in advance of the convention.
The first is something kind of scientific, and really cool. We've already tried to stump this a few times, it hasn't worked so far. If you can stump this, let us know.
The Force Trainer II: Hologram Experience: In 2009, Uncle Milton launched one of the most innovative Star Wars toys of all-time – The Force Trainer. This incredible toy enabled fans of all ages to move and control an object with the power of their mind using real brainwave technology and quickly became a hit with Star Wars fans and the media worldwide.
In 2015, Uncle Milton introduces The Force Trainer II: Hologram Experience, where once again you are the Jedi, but this time aspiring Jedi can use their concentration to move holograms! Imagine that you could raise an X-wing Fighter from the Dagobah swamp just like Luke Skywalker, battle Darth Vader, or build your own lightsaber with just the power of your mind! These magical scenes are re-created through hologram images and a wireless headset with real brainwave sensors that read and interpret your levels of concentration. The more you focus, the more successful you are in moving and controlling the hologram image and successfully completing the Jedi challenge. The hologram images and Jedi challenges come through a companion app included with the purchase of the product and powered by the user's tablet device which projects these holograms into the unique Jedi themed training base.


whether it's a good idea to use on humans.
CRISPR refers to short, repeated segments of DNA that provide the foundation for development of systems that can be programmed to actually edit specific segments of DNA.
CRISPR is easier to use and more efficient—not to mention cheaper—so this discovery is getting plenty of attention in the scientific world.
Why Are Ethicists Debating the Use of CRISPR in Humans?
However, the same technology could be used to make cosmetic enhancements and lead to permanent changes in the human species. Once the DNA is altered, the changes are passed on to subsequent generations; because we'd essentially be fast-tracking evolution without knowing how it would all come out, some ethicists want to put the brakes on this method of gene manipulation.
How do you feel about genetic manipulation in humans? Should we take advantage of technology that could make sick people well, even knowing that later it could be used for the wrong purposes, or should it be completely off-limits? I'd love to hear why you think (or why you don't think) it's ethical, so please join the conversation on my Facebook page or on Twitter.


This video was filmed during the 1993 YVR Airline Expo which was an airline collectibles show held at the River Inn in May of that year. The show was organized by Henry Tenby with help from Glen Etchells and Mike Brown. Due to the recession that show was poorly attended with very few people spending money, to the chagrin of those attending as depicted in this clip, filmed by Henry Tenby. Due to poor attendance this was the last Vancouver Airline Expo show organized by Henry Tenby and friends. The following airline fans appear in this clip: Mike Brown, John Kimberley, Erik Johannesson, Glen Etchells, Gary Vincent, John Wegg, John Dekker, Frank Morton, Terry Waddington, Billy Stefanchuck, Alex McPhee, and Bob Surman.


text:
RB #36
Charcandrick
College: Abilene Christian
'18 11.60 108
Released by Colts
West was released by the Colts on Saturday, John Breech of CBS Sports reports.
Analysis: West had an abbreviated training camp with the Colts, having only originally signed with the team Aug. 19, and was unable to crack a crowded running back depth chart. Marlon Mack, Nyheim Hines and Jordan Wilkins will likely be the trio handling the majority of Indianapolis' running game.
Published: Sat, Aug 31 at 2:57pm by Rotowire.com
Strong first impression
West rushed 13 times for 43 yards and a touchdown while catching all three of his targets for 27 yards in Saturday's 27-17 preseason loss to the Bears.
Analysis: West immediately got a chance to introduce himself to his new club with a heavy workload, and he probably did enough to put himself in position to make the roster given all the injuries to Indianapolis' other depth running backs. His touchdown came from 10 yards out in the first quarter.
Joining Colts
West signed with the Colts on Monday, Field Yates of ESPN reports.
Analysis: The Colts will add some veteran depth after losing Spencer Ware (ankle) and D'Onta Foreman (undisclosed) to injuries. West doesn't offer much juice as a runner, but his experience and pass-game skills could allow him to push Jordan Wilkins (foot) and Jonathan Williams (rib) for the No. 3 job. For all their backfield injuries the past few weeks, the Colts at least have managed to keep the important players (Marlon Mack and Nyheim Hines) healthy.
Published: Mon, Aug 19 at 12:02pm by Rotowire.com
Works out for Raiders
West had a tryout with the Raiders on Thursday, Field Yates of ESPN reports.
Analysis: The Raiders brought in a pair of veteran backs (West and Robert Turbin) for an audition, looking to fill out the backfield ahead of the offseason program. West himself is coming off a campaign in which he was released by the Chiefs in August, spent one preseason game with the Jets before being a roster casualty on cut-down day, and then returned to the Chiefs after Kareem Hunt was jettisoned. If West impresses Oakland's brass enough to earn a contract, he may have a difficult time landing on…read more
Published: Thu, Apr 4 at 1:37pm by Rotowire.com
Minimal impact in short season
West finished Week 17 against the Raiders with one carry for a loss of two yards.
Analysis: Even in the midst of a blowout, West took the field for just 10 snaps and has played a total of 30 in the past three games combined. Irrespective of whether Spencer Ware (hamstring) is ready for the playoff run, West is unlikely to make much of an impact with both Damien and Darrel Williams ahead of him on the depth chart. West finished his abbreviated regular season with the Chiefs with just two carries for one yard and two catches for 37 yards and a touchdown on three targets. His contract…read more
Published: Fri, Jan 4 at 8:37am by Rotowire.com
Records receiving score
West carried the ball just once for one yard in Sunday's 38-31 loss to the Seahawks. However, he also added two receptions for 37 yards and a score.
Analysis: While West remained clearly behind Damien Williams on the running back depth chart, his offensive snap count jumped up to 19. He took advantage by hauling in a 25-yard receiving score, his first time reaching the end zone since Week 15 of the 2017 season. Though his role is not robust, West does have some intrigue heading into Week 17 so long as Spencer Ware (hamstring) remains sidelined as he'll see a positive matchup against the Raiders. In addition, he's tethered to one of the most explosive…read more
Minimal showing in season debut
West saw just one snap from scrimmage and four on four special teams during Thursday's game against the Chargers.
Analysis: West was inactive in Week 14 after signing with the Chiefs, but Spencer Ware's (hamstring) absence afforded him an opportunity to dress for the first time this season Thursday. Despite suiting up, West appears to be well behind Damien and Darrel Williams in the pecking order for offensive snaps. He could fall even further off the radar if Ware is cleared to return in Week 16.
Suits up Thursday
West is active for Thursday night's game against the Chargers, BJ Kissel of the Chiefs' official site reports.
Analysis: This will be the recently re-signed West's first game for the Chiefs this season, but he has ample experience in the team's offense, having been with Kansas City from the 2015 season through the 2017 campaign. Look for him to work in a complementary role Thursday behind Damien Williams, who is starting in place of Spencer Ware (hamstring).
Inactive for Week 14
West (coach's decision) is inactive for Sunday's game against the Ravens, Adam Teicher of ESPN.com reports.
Analysis: After releasing Kareem Hunt last week, the Chiefs added West to the roster to shore up their backfield depth. West, who suited up in 49 regular-season contests for Kansas City over the past four seasons, won't need much time to get reacquainted with coach Andy Reid's scheme, but the veteran may represent more of an insurance policy than someone on whom the Chiefs are counting to contribute. Starter Spencer Ware, and reserves Damien Williams and Darrel Williams will dress Sunday while West…read more
Published: Sun, Dec 9 at 9:19am by Rotowire.com
Officially joining Chiefs
West signed with the Chiefs on Monday, Field Yates of ESPN reports.
Analysis: West was released by the Chiefs in August after playing 49 games for the team from 2014 to 2017. He briefly caught on with the Jets late in the preseason, but he was released at the beginning of September and has been a free agent ever since. West's experience working with Andy Reid could allow for a game appearance as soon as Week 14 against Baltimore, but there isn't much reason to expect the 27-year-old to handle anything more than a chance-of-pace role. West owns career averages of 3.8…read more
Published: Mon, Dec 3 at 12:43pm by Rotowire.com
Expected to join Chiefs
West is expected to sign with the Chiefs this week, Ian Rapoport of NFL Network reports.
Analysis: The Chiefs apparently prefer West to C.J. Anderson, who also was brought in for a visit Monday. The team presumably will give Spencer Ware another shot in a lead role, but West's familiarity with the offense could make him an immediate option as a change-of-pace back or passing-down specialist. The team does also have Damien Williams and Darrel Williams in the backfield, so there's no guarantee West earns a significant role.
Published: Mon, Dec 3 at 10:02am by Rotowire.com
May reunite with Chiefs
West and fellow running back C.J. Anderson are scheduled to visit the Chiefs on Monday, Ian Rapoport of NFL Network reports.
Analysis: Anderson is the bigger name and the more talented runner, but West has a huge advantage in scheme familiarity, having previously played for Andy Reid's Chiefs from 2014 to 2017. He didn't show any hint of explosiveness during that time, averaging 3.8 yards on 266 carries and 7.4 yards on 75 receptions, albeit with a stretch of fantasy relevance during the middle part of the 2015 campaign. West was released by the Chiefs on Aug. 22 and then cut by the Jets on Sept. 1. He could be useful on…read more
Patrick Mahomes touchdown pass to Charcandrick WestThu, Dec 27 at 1:17pm
Kansas City Chiefs quarterback Patrick Mahomes touchdown pass to Charcandrick West against the Seattle Seahawks.
Mahomes uses new sidearm angle on 25-yard TD passSun, Dec 23 at 7:47pm
Kansas City Chiefs quarterback Patrick Mahomes makes absurd throw across his body to runnning back Charcandrick West for a 25-yard catch-and-run touchdown in Week 16 of the 2018 NFL season.
Dolphins vs. Chiefs highlights | Week 16Sun, Dec 24 at 8:20pm
Watch as the Miami Dolphins take on the Kansas City Chiefs in Week 16.
Charcandrick West takes off for 25 yards after catching swing passSun, Dec 24 at 4:20pm
Kansas City Chiefs running back Charcandrick West uses speed to race up the field for a 25-yard gain against the Miami Dolphins.
Raiders vs. Chiefs highlights | Week 14Sun, Dec 10 at 4:37pm
Check out highlights from the Week 14 matchup between the Oakland Raiders and Kansas City Chiefs.
Charcandrick West gets North-South for 13-yard TDSun, Dec 10 at 12:32pm
Kansas City Chiefs running back Charcandrick West gets North-South for 13-yard touchdown.
Alex Smith shows frustration after failing to convert on 3rd downSun, Nov 26 at 12:47pm
Kansas City Chiefs quarterback Alex Smith shows frustration after failing to convert on 3rd down.
Landon Collins absolutely stuffs Charcandrick West to force 4th downSun, Nov 19 at 10:21am
New York Giants safety Landon Collins absolutely stuffs Kansas City Chiefs running back Charcandrick West to force 4th down.
Charcandrick West
RB #36 | Owner: FA


Business marketing is one of the biggest expenditures that a business has, therefore they need to know what they are doing is both current and effective at the same time. In today's digital world, video marketing is on the rise, and if you are not using it, then you may be missing out on one of the biggest marketing trends to hit the scene in 2017.
People are steadily spending more and more time online, and this is helped by some relatively new video streaming sites like Hulu and Netflix, meaning that more people are watching video content online than they ever have before. On average, people are spending around 2 hours every single day watching online content, with its growth in usage beating the likes of social media and digital radio. For marketers, this has opened up a whole new window of opportunity, and website builder uk help to show this growth in their 127 facts that you probably didn't know about video marketing.
Not only can you provide a lot of information in a short period of time, but also this type of marketing is relatively inexpensive. Videos are also easy to integrate into other sites, especially with some of the bigger social media channels. These social media channels have provided marketers with a fantastic way to reach targeted customers, plus with the ability for content to be shared, there is the advantage of reaching an even larger audience. Videos in social media increases sharing by ten times, so it is no wonder that companies and marketers alike are taking this on board and are starting to produce more video content.
As a pure video content site, YouTube is the biggest channel for video marketing, with 72% of markers using YouTube for their video marketing needs. Every single month the site has 182.2 million viewers per month and is the highest video provider. The rise of YouTube is one of the many pushes that have helped with the rise of video content, as currently the only site that has more hits than YouTube is Google itself. Both brands and individuals have been able to benefit from this growth, and marketers are starting to take notice. The main reason that marketers love video is that the consumer loves video, and it is a method that is now getting results.


text:
Pau Gasol: Lakers Need to Pound the Ball Inside
by SLAM Staff December 29, 2010
by Marcel Mutoni / @marcel_mutoni
It's not exactly time to push the panic button in Hollywood, but there's definitely cause for concern in Laker-land these days.
Following their humiliating defeat on Christmas Day against the Heat, Kobe Bryant fumed and promised hell for his teammates once they hit the practice court. They were supposed to come out guns a-blazing against the Spurs during their showdown last night, and though things began on a promising note, the wheels came flying off in the second half and the Lakers were once again run off the court.
Pau Gasol — who only put up eight shots against San Antonio — thinks one of the team's biggest issues is their offensive execution; namely, they're not getting the ball inside enough.
From the LA Times:
"I don't think we played the smartest game, put it that way," Gasol said. "I don't think we attacked smart out there. We've got to recognize what's going on and understand where our strengths are against certain opponents and try to exploit them."
"Whatever it is that needs to be fixed, you've got to do it all together," Gasol said. "It can't be an individual effort from nobody. It's got to be all together, on a string, like a family."
Phil Jackson agreed that Kobe Bryant's 27 shot attempts against the Spurs' swarming defense (coupled with 19 misses) were far too many, but once again, he pointed out that Gasol wasn't nearly assertive enough and failed to play well.
It's no secret that the key to the Lakers' success over the last three years has been their dominant inside play. With Andrew Bynum's early-season injury issues, plus Gasol's recent struggles, the team hasn't been able to put this proven formula to full use yet.
The good news for the Lakers is that January is chock-full of relatively easy and winnable games, where the touches for Gasol and other bigs should be plentiful.
Kobe Bryant Los Angeles Lakers Pau Gasol Phil Jackson San Antonio Spurs
Report: J.R. Smith 'Unlikely' to Join the Los Angeles Lakers
Lonzo Ball Ready for 'Fresh Start' With the Pelicans
Anthony Davis Would Put Lakers Roster 'Up Against Anybody'


Dvorak's Piano Trio op. 90 bears the nickname 'Dumky', derived from the Ukrainian dumka, a melancholy lament in ABA form. Dvorak had already used the dumka as an element of some of his Slavonic dances and also included it in a few of his chamber music compositions, such as the piano quintet in A.


text:
Antenatal diagnosis of heart disease
Lindsey Allan
Director of the Echocardiography Laboratory, New York Presbyterian Hospital, New York, USA
Professor Lindsey Allan, New York Presbyterian Hospital, Columbia Campus, 3959 Broadway, 2-North, New York, NY 10032, USA email:la48{at}columbia.edu
In 180, several reports appeared almost simultaneously of the identification of normal cardiac anatomy in fetal life. The recognition of several different forms of structural cardiac anomaly followed soon after. At this time, cardiac evaluation was confined to pregnancies at increased risk of congenital heart disease (CHD), such as those with a family history of CHD or where extracardiac malformations had been detected. However, up to 90% of CHD occurs in pregnancies where there are no known high risk features. For this reason, in 1985 a group based in Paris put forward the idea of teaching the obstetrician to assess the heart in a simplified form during routine obstetric scanning, which was well established at that time in France. As a result, four chamber view scanning became an integral part of the fetal anatomical survey in many countries by the end of the 1980s. In the early 1990s, some authors suggested extending the cardiac assessment to include great artery scanning in order to detect a higher proportion of cases of major congenital heart disease.1 If cardiac screening is confined to the four chamber view, about 2/1000 studies will be abnormal and would represent about 60% of the major heart disease seen in infants. If the great arteries are also examined, about 3/1000 cases would be abnormal, and over 90% of major heart disease would be detectable prenatally. Therefore, in ideal circumstances, the vast majority of serious heart malformations could be detected before 20 weeks' gestation. Unfortunately, the reality is far from this for several reasons:
differing policies for obstetric scanning
differing guidelines for scanning
differing skill at scanning.
About 2% of live births have fetal structural malformations, the majority of which can be detected by ultrasound. About 25% of these malformations are cardiac in nature and about half of these are serious or life threatening. Despite these facts, and the opportunity during pregnancy for comprehensive evaluation of the fetal anatomy in fine detail, there is no universal agreement as to either the necessity for or the technique of fetal anatomical scanning. Some countries, such as Norway, France, and Germany, have instituted a government sponsored policy for routine anatomical screening by ultrasound. In the UK, routine screening is generally well accepted but not uniformly adopted or standardised in all parts of the country. In the USA, routine scanning is not recommended but is allowed only for specific indications, although these are fairly all encompassing. In practice, this leads to later scanning in the US and "targeted" scanning rather than a comprehensive anatomical survey.
Where an anatomical survey is performed, the timing of the scan varies—for example, in France it is usually between 20–22 weeks, in Norway 18 weeks. In general, the later in the mid-trimester that scanning is performed the more successful will be the detection of abnormalities, partly because scanning becomes easier and partly because some lesions become more evident as pregnancy advances. However, later detection of malformations will limit the options for interrupting the pregnancy or make it much more difficult both emotionally for the parents and technically for the obstetrician. Thus, the ideal policy would be a universal anatomical scan at a compromise time of between 18–20 weeks' gestation.
Although there are recommended guidelines for the technique of fetal scanning provided by the Royal College of Obstetricians and the American Colleges of Obstetrics and of Radiology, none are enforced and there is no standardisation of practice. This would be much easier in the UK than in the US and could be universally computerised to a standard format, but to my knowledge this is still not happening.
The skill involved in scanning is extremely variable for several reasons. A sonographer, whether a technician, an obstetrician, or a radiologist, needs:
to train with a high volume of patients
to maintain skills continuously with sufficient numbers of patients
to be exposed continually to a critical number of abnormal fetuses
to be provided with constant feedback and retraining.
In order to achieve and maintain a high level of expertise in scanning, the practitioner should be doing this as a full time or nearly full time commitment. Where ultrasound is performed in small numbers, the requisite practice necessary is quite unattainable. Nearly all scanning in the UK is hospital based, with delivery numbers usually over 2000 per year. Therfore, the necessary volume of patients is less of a problem in the UK than in the US, where scanning often takes place in private offices in small numbers.
As a result of the differing policies and standards in obstetric ultrasound, the results of the detection of all malformations in the screening setting varies with the organ involved, but is particularly poor in reference to the heart. During screening, reported detection rates vary between 4.5% and 96% for major CHD, with the most papers giving a rate of 15–20%.2-6 This is consistent with recent experience in our referral centre for paediatric cardiology, when 18% of infants requiring cardiac surgery in the first year of life during 1998 were identified prenatally. The rate of detection of four chamber view anomalies prenatally is better, but averages only about 50%,7 ,8 despite the fact that universally nearly all pregnancies are scanned at least once (figs 1, 2, and 3). Thus, the technology and personnel are in place in obstetric care, but they are not used to their maximum capability.
A normal four chamber view showing a heart of normal size (about one third of the thorax) in a normal position within the thorax (about 45° to the midline). There are two equally sized atria and two equally sized ventricles. In the moving image both atrioventricular valves would be seen to open equally. There is a "cross" at the crux of the heart, where the atrial and ventricular septum meet at the insertion of the two atrioventricular valves. LA, left atrium; RA, right atrium; LV, left ventricle; RV, right ventricle.
The fetal heart is oriented similarly to the normal example seen in fig 1. The most common anomaly detected prenatally is depicted. There is no "cross" appearance at the crux of the heart owing to a common atrioventricular junction and a complete atrioventricular septal defect. Despite the obvious difference between this and the four chamber view of the normal heart, only about 50% of cases are detected in fetal life.
This fetal heart is oriented similarly to the normal example shown in fig 1. The second most common anomaly detected prenatally is depicted. The left atrium is small. The left ventricle is hypoplastic with the right heart forming the apex. The mitral valve is not patent. This is mitral atresia, in its most frequent setting of the hypoplastic left heart syndrome. Again, this defect is only detected prenatally in just over half of cases.
Cardiac evaluation at referral to paediatric cardiologists
A common misconception among paediatric cardiologists is that fetal cardiology is the same as paediatric echocardiography but a bit smaller. Therefore, nearly all paediatric echocardiographers in the US would not hesitate to offer fetal echocardiography as part of their practice. However, it is clear that quite a different spectrum of disease is seen prenatally,9 and fetal heart scanning is quite a different skill. Success in accurate diagnosis will be partly dependent on technical skills, which again require training and practice. In the US, there are recommended guidelines for training, and a minimum number of scans in order to maintain skills, but these are not commonly known and certainly are not adhered to. Experience of fetal malformations therefore is so diluted that few practitioners have sufficient numbers to maintain a high standard of expertise. In addition, most paediatric cardiologists know little of fetal medicine and obstetric pathology, which have an important influence on fetal cardiac evaluation.
Although the majority of paediatric cardiology centres in the UK now offer fetal echocardiography, this is usually confined to one or two cardiologists and, theoretically, there should be sufficient numbers in each regional centre to provide adequate experience. However, there is no system of independent review or systematic quality control in place anywhere, to my knowledge. Indeed, in the US, pathological correlation after termination of pregnancy is quite rare for various reasons, not least being the difficulty in obtaining remuneration for pathological services, despite their vital role in quality control.
Problems and limitations
Limitations of fetal echocardiography are related to:
subtle lesions, such as small ventricular septal defects
developing or progressive lesions
lesions which are undetectable before birth.
Image quality is dependent on the skill and experience of scanning in addition to local factors such as gestational age, fetal position, and the thickness of the maternal abdomen. Maternal obesity is an increasing problem everywhere but particularly in the US, especially in the poorer states. This is the most important limitation to image quality, which in turn will limit confidence in excluding malformations in the fetus in any anatomical system. Even though the resolution of ultrasound equipment has improved vastly since the early 1980s, a great deal more detail is also expected during fetal scanning, and there are a significant proportion of patients where detail is just not possible because of the way scanning is presently organised. As up to 10% of adult Americans are said to be morbidly obese, this group should probably be managed with a different strategy, perhaps with early transvaginal scanning instead of transabdominal scans; to date this problem has not been addressed by the ultrasound community.
In a small proportion of fetuses, CHD becomes evident or more evident as pregnancy progresses.3 Thus, the cardiac evaluation can be normal at 18 weeks although a significant malformation is found later or at birth. This is true of some cases of aortic or pulmonary stenosis, cardiac tumours, or cardiomyopathies. It is rare for a life threatening malformation to arise after 20 weeks' gestation, but it can occur. In addition, minor lesions can be overlooked because of the limits of ultrasound resolution, such as small ventricular septal defects; a persistent arterial duct and an atrial septal defect cannot be predicted prenatally as these communications are always present prenatally. Thus, there are confidence limits with even detailed fetal heart scanning. It is important to realise, however, that confidence limits may be much wider with poor image quality.
By 14 weeks' gestation, the cardiac connections can be identified in many patients transabdominally. The connections can be seen in almost all patients at this stage transvaginally, however, and in much finer detail than on the transabdominal scan. Expertise with this technique is essential and the paediatric cardiologist should use the experienced gynaecological technician to display the fetal cardiac images, in a setting where transvaginal scanning is routine. At present, a cardiac scan at 14 weeks is confined to the high risk patient, such as those with a family history of CHD or those whose fetus has been found to have an increased nuchal fold.
The data concerning nuchal translucency in early pregnancy (10–12 weeks) are fascinating and intriguing.10 When the translucent region at the back of the neck is increased in size, there is a high incidence of associated chromosomal anomalies, cardiac malformations, or both, with the incidence of heart disease increasing with increasing nuchal thickness. Conversely, 50% of fetuses subsequently found to have CHD had an abnormal nuchal fold measurement. This may reflect the "insult" which has caused the fetal heart malformation. Extension of the nuchal translucency screening program, which has received little attention in the US so far, is likely to have important implications for the improved detection of both chromosomal and cardiac malformations. In addition, the earlier the diagnosis of fetal malformation is made in pregnancy, the more likely are parents to choose interruption. If a pregnancy with increased nuchal thickening is continuing, fetal echocardiography is recommended, ideally at 14 weeks, which is the earliest time a cardiac scan can be completely comprehensive.
Impact on paediatric cardiology
The impact on paediatric cardiology may include:
reduced prevalence of CHD, especially complex forms
improved morbidity after delivery and perioperatively
improved perioperative mortality.
Decisions about termination of pregnancy are influenced by many different factors, including gestational age at diagnosis, social circumstances, and socioeconomic group. Generally speaking, however, if complex heart disease is detected in a pregnancy at less than 20 weeks' gestation, over half the parents will choose to interrupt the pregnancy. This is true in the UK and the US. Thus, about half of the complex forms of CHD which the paediatric cardiologist would expect to see and treat postnatally may only be seen once in prenatal life. As fetal cardiology preferentially detects the complex forms of heart disease which require long term cardiac care and follow up, this is bound to have an impact on paediatric cardiology in the future. As an example of this, termination of pregnancy has been shown to have lowered the prevalence of pulmonary atresia in England and Wales, compared with Scotland and Ireland where either the diagnosis was not made in the fetus or termination was not chosen.11 The frequency of complex one ventricle type cardiac repairs may therefore become less common in the coming years.
Some forms of CHD are associated with early decompensation and even death of the infant before the malformation can be recognised and treated. This applies mainly to those where either the pulmonary or systemic circulation is dependent on the patency of the arterial duct, or the lesions which require "mixing" at an adequate atrial septal defect such as transposition of the great arteries or total anomalous pulmonary venous drainage. It appears intuitively obvious that if CHD is recognised prenatally and delivery takes place in or near a paediatric cardiology centre, thus avoiding delay in diagnosis and emergency transfer of a sick neonate, the morbidity for the infant will be minimised. This has been shown in several studies although improvement in mortality has been harder to prove, partly because fetal echocardiography preferentially detects more severe forms of CHD which have a higher mortality per se.12 ,13 However, a recent study of infants with transposition of the great arteries, where there were adequate numbers to answer this question, showed conclusively that there was a much lower mortality in those cases prenatally diagnosed.14 Thus, the impact on paediatric cardiology, if fetal heart scanning improved to the ideal level of expertise, would be a decrease in the number of complex malformations, but those patients with CHD who come to surgery would do so in optimum status without prior insult. This would have a potentially significant effect on saving of resources by reducing complex disease and improving both the cardiac and neurological outlook for the survivors of treatment.
Certainly in the US, and increasingly in the UK, one is continually aware of the fear of litigation. One would imagine that this would result in more rigid standards and codes of practice in the US, but in reality this does not appear to happen. Litigation is so sporadic, and frequently occurs in the most unexpected circumstances, that it does not seem to deter careless attention to training or practice guidelines. In the case of an obstetrician who misses a four chamber view anomaly on a prenatal scan, the parents can sue for wrongful life. To my knowledge there is no precedent for this in court, although out of court settlements have been made in such circumstances. However, the RADIUS study was a large multicentre scanning program based in the midwest and eastern US, where no cardiac malformation was detected outside tertiary centres, despite a supposedly uniform scanning format.15 This publication gives the obstetrician a reasonable defence that such malformations are not detectable by the present general "standard of care". A little threat of litigation may be no bad thing if it encourages self regulation within the medical profession, uniform codes of practice, and quality control initiated by doctors themselves. However, an atmosphere of litigation, especially if the application and outcome of suits are extremely unpredictable, leads to bad clinical practice, with over investigation and over treatment.
Differences between the UK and the US
Some of the differences between the UK and the US in terms of the practice of fetal cardiology have been alluded to above. The most striking difference in medical practice is that in the UK there is, in general, an atmosphere of collective responsibility for the health service among doctors, and for the impact of care on society as a whole. Despite the dissatisfaction among the medical profession in the UK, which appears to have grown in the last 10 years, the organised nature of the UK National Health Service provides a unique opportunity for imposing and maintaining uniform standards of practice and for collecting data for quality control across the whole service. This would demand a willingness on the part of practitioners to be part of a drive to improve the quality of service and to confront the hazards of "audit", but such an effort would be applicable to many aspects of obstetric and paediatric cardiology practice.
Achiron R,
Glaser J,
Gelernter I,
(1992) Extended fetal echocardiographic examination for detecting cardiac malformations in low risk pregnancies. BMJ 304:671–674, .
Sharland GK,
Allan LD
(1992) Screening for congenital heart disease prenatally. Results of a 21/2 year study in the south east Thames region. Br J Obstet Gynaecol 99:220–225, .
Yagel S,
Weissman A,
Rotstein Z,
(1997) Congenital heart defects. Natural course and in utero development. Circulation 96:550–555, An impressive number of patients, more than 22 000, were screened between 1990 and 1994 for fetal anomalies, including cardiac malformations. Of 168 cases of CHD, 80% were diagnosed before 22 weeks' gestation. However, a small proportion of cases evolve or become evident only in the last trimester of pregnancy.
Buskens E,
Grobbee DE,
Frohn-Mulder IM,
(1996) Efficacy of routine fetal ultrasound screening for congenital heart disease in normal pregnancy. Circulation 94:67–72, .
Tegnander E,
Eik-Nes SH,
Johansen OJ,
(1995) Prenatal detection of heart defects at the routine fetal examination at 18 weeks in a non-selected population. Ultrasound Obstet Gynecol 5:372–380, .
Todros T,
Faggiano F,
Chiappa E,
(1997) Accuracy of routine ultrasonography in screening heart disease prenatally. Gruppo Piemontese for prenatal screening of congenital heart disease. Prenatal Diagn 17:901–906, .
Montana E,
Khoury MJ,
Cragan JD,
(1996) Trends and outcomes of prenatal diagnosis of congenital cardiac malformations by fetal echocardiography in a well defined birth population, Atlanta, Georgia, 1990–1994. J Am Coll Cardiol 28:1805–1809, A population based study which identified 1589 cases of CHD during the five year period from 1990 to 1994. Overall, 6% were identified prenatally, rising from 2.6% to 12.7% over time. Four chamber view anomalies, such as the hypoplastic left heart syndrome, increased to a 40% detection rate by the end of 1994.
Allan LD. Atrioventricular septal defect in fetal life. Am J Obstet Gynecol In press.
Allan LD,
Milburn A,
(1994) Prospective diagnosis of 1,006 consecutive cases of congenital heart disease in the fetus. J Am Coll Cardiol 23:1452–1458, A sufficiently large series of fetal CHD to allow meaningful comparison of the spectrum of disease seen prenatally with postnatal life. There is over representation of disease where the four chamber view is abnormal and a relative paucity of great artery anomalies. The method of selection of cases for fetal echocardiography also increases the rate of chromosomal and extracardiac anomalies.
Hyett J,
Perdu M,
Sharland G,
(1999) Using fetal nuchal translucency to screen for major congenital cardiac defects at 10–14 weeks of gestation: population based cohort study. BMJ 318:81–85, In a series of over 29 000 chromosomally normal fetuses, where the nuchal fold was measured between 10–14 weeks' gestation, over 50% of those with congenital heart disease had values above the 95th centile. Thus, fetuses with nuchal thickening constitute a newly recognised but extremely important high risk group for referral for fetal echocardiography.
Daubeney PE,
Cook AC,
(1998) Pulmonary atresia with intact ventricular septum: impact of fetal echocardiography on incidence at birth and postnatal outcome. UK and Eire collaborative study of pulmonary atresia with intact ventricular septum. Circulation 98:562–566, A large series of cases of pulmonary atresia with intact ventricular septum were identified in a multicentre study over a 4 year period. Of 83 cases recognised in fetal life, there was a high rate of termination of pregnancy. Of the continuing pregnancies who reached live birth (29), no difference in survival could be shown in those prenatally diagnosed. However, the worst end of the spectrum of disease was removed from the series as a result of termination. The high rate of detection coupled with the option of termination led to a reduced prevalence of live born infants with this lesion in England in comparison to other parts of the UK and Eire.
Chang AC,
Huhta JC,
Yoon GY,
(1991) Diagnosis, transport, and outcome in fetuses with left ventricular outflow tract obstruction. J Thorac Cardiovasc Surg 102:841–818, .
Copel JA,
Tan AS,
Kleinman CS
(1997) Does a prenatal diagnosis of congenital heart disease alter short-term outcome? Ultrasound Obstet Gynecol 10:237–241, .
Bonnet D,
Coltri A,
Butera G,
(1999) Detection of transposition of the great arteries in fetuses reduces neonatal morbidity and mortality. Circulation 99:916–918, Of 318 neonates with transposition of the great arteries, 68 were recognised prenatally. There was improved morbidity before surgery in the prenatally diagnosed group and there was no mortality either before surgery or perioperatively. In contrast in the group diagnosed in postnatal life, 15 died before surgery and there were 20 perioperative deaths. This is the only study to date which has had the statistical power of numbers to answer this question meaningfully.
Ewigman BG,
Crane JP,
Frigoletto FD,
(1993) Effect of prenatal ultrasound screening on perinatal outcome. N Engl J Med 329:821–827, .


text:
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We all know how difficult it can be choosing a hotel in an unknown city or town – nobody wants to end up ruining their holiday with bad accommodation. So why not use a Best Western discount code to get great deals on a hotel chain you can trust? Whether you're planning a well deserved break in the country or a few nights in the city, a Best Western promo code will save you money when you book.
One of the UK's best-loved hotel chains, Best Western has been providing customers around the world with reliable, quality accommodation since they were established in America in 1946. Originally an informal link between independently owned hotels, Best Western has grown to boast a presence in over 80 countries around the world, with more than 4,000 properties under their name. In the UK, they own and operate over 270 individual hotels, each offering the same excellent accommodation and exceptional value – wherever you decide to visit.
At Best Western they believe that booking accommodation shouldn't be a gamble, which is why they offer the opportunity to book their properties confident in the knowledge you'll be getting the very best whether you're looking for a smart city centre hotel or something quaint and relaxing in the countryside. All of their hotels are designed with their own individual personalities in mind, so you can rest assured that you'll be booking accommodation with character and not some faceless, modern box hotel. And all of their locations are chosen to be particularly convenient whether they're close to the sea or within walking distance of popular transport links.
Because all of Best Western's hotels are independently owned and operated, you get the best of both worlds – the individuality and personal service of an independent hotel combined with the quality reassurance of booking with a known chain. All Best Western hotels offer plenty of benefits such as free wi-fi and excellent restaurants serving delicious, locally sourced food. Some even boast AAA Rosette winning restaurants where you can enjoy some truly exceptional dishes crafted by award-winning chefs, or their own on-site wineries where they produce their own wine and champagne. And with locations as diverse as central London, Exmoor National Park and the Scottish Highlands, a holiday at a Best Western Hotel is sure to be an experience you'll never forget.
Want to book your nest holiday with Best Western? With a Best Western discount code you can enjoy fantastic savings on stays at any of their top hotels. From romantic escapes in the middle of the wild countryside to city shopping breaks in some of the UK's top cities, Best Western offers a chance to get away from it all without breaking the bank.
Independently owned hotels offer guests quality and individuality.
Browse our website until you find a Best Western discount code that suits you, then navigate to their website to begin your search.
Enter your dates and room details and click 'Find a hotel'.
Choose a hotel and click 'More info'.
Enter your Best Western voucher codes where applicable.
Want to find out more about fantastic holidays with Best Western? Why not pay a visit to the company's dedicated YouTube channel? You'll enjoy access to lots of exclusive content including travel guides, video hotel tours and more. You can also use this channel to find out more about saving money with a Best Western promo code.
If you've enjoyed browsing accommodation with Best Western, why not take a look at more great deals on hotels and more at stores like lastminute.com and booking.com. Or, if those aren't up your street, you'll find plenty more deals to browse in our Travel section.
Enter your Best Western discount code where applicable.
Enter your payment details and click 'Book room' to complete your booking.
Need to speak to the team at Best Western? Whether you have a question about your booking, want to know more about an individual hotel or just want to find out how you could make big savings with a Best Western voucher code, you can contact the Customer Services department by telephoning 0844 5 767676.
Want to discover more from Best Western? The company maintains a profile across all your favourite social media networks. Follow them to enjoy exclusive access to lots of interesting content including travel tips, fun articles, promotions, competitions and more. You can also use these pages to find out more about saving money with Best Western voucher codes.
Don't forget to check them regularly, as you can never be sure when free Best Western vouchers might be waiting for you!
Buy now online at www.bestwestern.co.uk.
My husband love to get away for the weekend, but we're tired of booking poor quality hotels. That's why I was delighted to discover a Best Western discount code online. Best Western offers reliable quality, comfortable accommodation and great food in all of their 270+ hotels around the UK at bestwestern.co.uk – and now we can book them at a great rate thanks to our Best Western promo code. So if you want to take the guess work out of your holiday and enjoy a hassle-free break away, redeem the Best Western discount code!


Lauren I. Lyon Krzemienski, 66, of Beaver Falls, died Sunday, November 27, 2011 in Providence Health Care Center.
She was born September 20, 1945 in Beaver Falls. She was the daughter of the late George A. and Ida Headly Lyon. Lauren was a member of Divine Mercy Parish, Holy Trinity Church. She worked as a kiln worker at the McDaniel Corp.
She is survived by her husband of 39 years, Stanley 'Bucky' Krzemienski; two sisters and a brother-in-law, Beverly Lyon, West Mayfield, and Paula and Ted Blazak, Ellwood City; a brother Larry Lyon, Enon Valley, also several brothers-in-law and sisters-in-law, nieces and nephews.
As per Lauren's wishes, a private family blessing service was held. Father James Farnan officiated.
Private interment followed in St Mary's Cemetery.
Arrangements were handled by the LUTTON BEAVER FALLS FUNERAL HOME, 1117 Fifth Ave., www.luttonfuneralhome.com.


The 30th Annual Wisconsin Governor's Conference on Tourism took place last week at Potawatomi Hotel & Casino in Milwaukee. Close to 1,000 attendees converge on a city once a year to learn what's new in the tourism industry and, of course, catch up with old friends.
This year Andrew McCarthy – yes THAT Andrew McCarthy – shared his stories of travel across the world. His travel memoir THE LONGEST WAY HOME, became a New York Times Best Seller. Andrew's keynote was more inspirational than educational – talking about the spiritual journey he has gone through on his many travels. Even a walk down 42nd Street in New York City, where he has lived for many years, became an eye-opening experience for a native New Yorker. His talk was a reminder that when visitors come to destinations in Wisconsin, you never know what journey they may be on.
While his stories of travel were interesting, I couldn't quite get this image out of my mind.
On Day Two, the entire group was practically scared to death by Dr. Jennifer Golbeck's insightful take on Big Social Data. Dr. Golbeck is the director of the Social Intelligence Lab at the University of Maryland. She is a pioneer in the field of social data analytics, discovering people's hidden attributes from their online behavior. One of her papers dives into how a person's interactions on Twitter can predict their personality. While this is data that we love as advertisers, it's a bit scary from a consumer standpoint. It's fairly harmless to use this data to determine if a person is in the market for a vacation or a new car, but does it cross a line of privacy if employers are using this type of data to vet potential employees?
If you are starting to feel a little freaked out about this level of data being stored in cyberspace there are ways to delete your historical social media history and interactions in order to fly "under the radar." While this seems counterintuitive for someone in marketing, it does seem like an interesting experiment to conduct to see how advertisers find you and if they are able to serve relevant messages. This practice is also a good way to clean up old accounts you might have opened in the past that were allowed to access your information. Deseat.me is one tool that can help you clean up your online presence efficiently.
On the positive side of Big Social Data, there are now tools popping up that use this information to help us determine how to interact more effectively with those in our business circle. Crystal Knows is an intuitive site that analyzes you and your contact list based on social media information and other public data. These profiles are a combination of estimated personality insights intended to provide a "best guess" about a person's preferred communication style. While these are best guesses, my personality assessment was pretty spot on.
Dr. Golbeck's keynote was a reminder that the depth of data at everyone's fingertips can be used for good or bad. As marketers, let's continue to be responsible with the information we can access. The brands you represent will only succeed because of it.
As we see every year, the tourism industry is constantly changing. How people research and book vacations is in constant evolution. The one thing that does remain constant is that Wisconsin is made up of thousands of tourism professionals who love showing off their great state to the millions of travelers passing through each year.
I hope to see you at next year's WIGCOT in Appleton!
Businesses have had to come to grips with the ways that consumers use media and how they react to these messages in different settings – be it car, work or living room.
The music industry is the proverbial "canary in the coal mine" for any business model that is based on creating content.


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Bakery Blog
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Issue #
Mailing subject
1 2016-05-05 02:56:38 196 Happy Mother's Day!
2 2016-02-18 21:23:10 195 Valentine's Day is Over! Yaaaay!
3 2016-01-28 19:20:44 194 We Get Around!
4 2015-12-03 01:49:32 193 How About a Free Cookie?
5 2015-07-01 19:31:23 192 Happy 4th!
7 2015-06-11 23:18:12 191 Goodbyes and hello
8 2015-03-04 19:23:28 190 Perfect Weather!
9 2015-02-19 07:17:15 189 We've Got the Hots for You!
10 2015-02-13 02:17:20 188 Whatsa Matter, Bucky?
11 2015-02-06 08:37:42 187 Welcome to February!
12 2015-01-21 01:27:49 186 Show of Hands...
13 2015-01-16 02:15:06 185 Back in the Swing of Things
14 2015-01-08 12:46:44 184 Did'ja Ever Notice...
15 2014-12-30 00:59:40 183 Happy New Year!
16 2014-11-28 02:50:36 182 Squirrel Me!
17 2014-11-20 13:52:39 181 FREE to Good Home!
18 2014-11-12 08:30:47 179 A Scam What Am
19 2014-10-24 22:00:59 178 Cider & Soup
20 2014-10-02 01:15:00 177 Get out your jacket!
21 2014-09-26 01:59:34 176 Pick a Peck
22 2014-09-19 01:20:41 175 Change is afoot...
23 2014-08-29 03:35:32 174 Work, school
24 2014-08-22 09:01:34 173 What the heck is a "Frishment?!?"
25 2014-08-22 02:07:49 172 Don't Scare the Frishment
26 2014-08-15 01:29:05 171 August 15, 2014
27 2014-07-25 00:51:34 170 It's Still Summer!
28 2014-07-03 21:43:20 169 The Trouble With Excellence...
29 2014-06-20 10:07:37 168 This little baker went to market...
30 2014-04-21 23:58:36 167 End of a Season
31 2014-04-18 04:18:03 166 Happy Easter!
32 2014-04-03 02:35:06 165 Mystery!
33 2014-03-25 00:53:26 164 Hello, Spring!
34 2014-03-06 01:18:42 163 Zzzzzzz
35 2014-02-27 00:42:14 162 Fungus!
36 2014-02-19 08:57:56 161 Be on the lookout...
37 2014-02-07 01:12:36 160 100% Chance of Ice!
38 2014-01-30 02:07:44 159 Hey! Polar Vortex!
39 2014-01-22 08:43:35 158 The Spice of Life
40 2014-01-17 09:17:02 157 New year, old memories
41 2014-01-07 02:55:42 156 Happy 2014
42 2013-12-05 01:35:45 155 Merry!
43 2013-11-20 04:06:05 154 Making a list...
44 2013-11-13 01:43:39 153 Warm up!
45 2013-11-01 01:06:38 152 Pumpkin
46 2013-10-17 22:49:48 151 Cider Fest!
47 2013-10-04 22:37:37 150 "It's Like Deja Vu...
48 2013-09-27 09:00:59 149 Take a breath
49 2013-09-20 02:25:17 148 Busy weekend!
50 2013-09-13 08:12:29 147 Settling in to September
51 2013-08-30 02:48:03 146 School's Back!
52 2013-07-25 02:36:38 145 "Oh No!
53 2013-07-12 03:09:35 144 Rye Bread!
54 2013-06-28 08:56:23 143 Which Weekend?
55 2013-06-20 01:38:11 142 Bakerydad and the Worms
56 2013-06-14 01:20:37 141 VOTE FOR STAHL'S!
57 2013-02-08 01:31:51 140 Ice, please!
58 2013-01-21 03:55:25 139 Tic Toc
59 2012-12-07 01:52:10 138 Festive Weekend
60 2012-11-28 22:25:41 137 See you downtown
61 2012-11-17 00:16:30 136 Turkey Exchange!
62 2012-11-03 01:53:34 135 Don't forget to remember
63 2012-10-29 03:07:57 134 Alright,
64 2012-10-19 02:57:21 133 Scurry on over!
65 2012-09-28 02:33:40 132 Raisin Redux - sort of.
66 2012-09-15 00:35:10 131 Clear Skies
67 2012-09-08 01:37:17 130 So many Breads...
68 2012-08-31 07:47:50 129 One foot in the groove...
69 2012-08-10 23:12:29 128 25-cent Ice Cream!
70 2012-08-03 08:33:44 127 Settlng in....
71 2012-07-02 01:03:03 126 Happy 4th!
72 2012-06-24 22:25:53 125 A long tme ago, in a galaxy far, far away...
73 2012-06-15 09:13:30 124 Yo, yo, Daddio!
74 2012-05-25 01:35:03 123 Celebrations
75 2012-05-10 22:40:57 122 Happy Mother's Day!
76 2012-05-04 02:32:22 121 Congrats, Grads!
77 2012-04-27 01:45:49 120 Who's Your Mama?
78 2012-03-29 01:46:36 119 Spring has Sprung?
79 2012-03-13 22:46:00 118 Pi in the Sky
80 2012-03-02 01:51:32 117 In like a lion and out like a lamb...
81 2012-02-24 00:51:41 116 Cherries!
82 2012-02-10 01:00:48 115 A Rose by Any Other Name...
83 2012-02-03 08:44:56 114 Are you ready for the S....
84 2012-01-27 20:17:46 113 Ahhh, January...
85 2012-01-19 00:37:10 112 Short & Sweet
87 2011-12-23 02:53:01 110 Merry Christmas!
88 2011-11-15 23:43:22 109 Cheesy Treesies Soup
89 2011-10-28 07:51:32 107 Market & Soup Update...
90 2011-10-20 22:47:33 106 Deciderly Different!
91 2011-10-12 21:57:27 105 We don't need no stinkin' calendar
92 2011-09-28 00:01:41 104 Our loss...
93 2011-09-23 03:19:26 103 All right, already!
94 2011-09-16 04:24:14 102 Early Fall
95 2011-08-26 10:06:32 101 Songs of the Miller
96 2011-08-17 02:53:51 100 Two places at once
97 2011-08-03 09:56:20 99 Entertaining August
98 2011-07-29 09:44:29 98 It Ain't the Heat...
99 2011-07-22 08:05:46 97 Everyone talks about the weather...
100 2011-07-13 06:44:06 96 Ssssssnake
101 2011-07-08 07:51:04 95 Happy Returns
102 2011-06-24 17:00:05 94 Sum, sum, summertime!
103 2011-06-08 00:12:26 93 Goldilocks and the farmers' markets
104 2011-06-03 00:49:17 92 Masterpiece!
105 2011-05-25 23:12:04 91 Ciao, Angelo...
106 2011-05-05 03:22:34 90 Hi Mom!
107 2011-04-22 09:51:36 89 Busy, Busy
108 2011-04-15 21:39:36 88 Bread!
109 2011-03-24 04:04:04 87 Go Eat a Kite!
110 2011-03-16 22:31:45 86 Make Some Noise!
111 2011-03-09 22:00:41 85 Mulliga- What??
112 2011-03-01 02:05:17 84 TL;DR
113 2011-02-23 02:31:43 83 Rich & Creamy
114 2011-02-14 01:49:23 82 Spread the love!
115 2011-02-09 04:16:48 81 Pop Quiz
116 2011-02-02 02:53:41 80 The Big Game
117 2011-01-27 09:12:48 79 Fruit Soup
118 2011-01-19 00:50:31 78 January Goodies
119 2011-01-13 02:22:51 77 Break's Over!
120 2010-12-31 15:48:29 76 Happy New Year!
121 2010-12-23 08:05:26 75 Two Days 'til Christmas
122 2010-12-16 06:35:49 74 Chilly Autumn!
123 2010-12-09 21:29:20 73 Ruh Roh!
124 2010-11-17 02:27:35 72 Gobble Gobble
125 2010-11-04 03:16:21 71 Soup? Soup!
126 2010-10-29 04:26:50 70 What're YOU Lookin' At?!?!
127 2010-10-22 02:07:10 69 Playing Favorites
128 2010-10-02 01:59:30 68 Happy October!
129 2010-09-17 04:08:11 67 Now you see us...
130 2010-08-27 01:03:00 66 And.....They're Back!
131 2010-08-20 09:07:58 65 Back to School...Blues
132 2010-08-12 09:40:15 64 Dear Mr. Weatherman...
133 2010-08-05 09:05:41 63 Happy NFMW
134 2010-07-30 09:33:16 62 Dilly of a Market...
135 2010-07-16 08:22:44 61 What are we... Cracked?!?
136 2010-07-09 06:28:22 59 Hey You!
137 2010-06-11 04:03:50 58 Welcome, summer!
138 2010-05-28 01:50:15 57 2010 Haymaker Farmers' Market
139 2010-05-07 16:59:02 56 Hi, Mom!
140 2010-04-21 02:21:53 55 See ya, snow!
141 2010-04-15 17:44:53 54 Spring has sprung...
142 2010-03-24 03:00:42 53 Prepare to be assimilated...
143 2010-03-16 23:24:06 52 Hey! Where'd the snow go??
144 2010-03-04 02:44:32 51 Longer than a Tweet
145 2010-02-25 02:49:18 50 'Shrooms!
146 2010-02-18 02:40:02 49 Stahl's 411 e-newsletter for 2/17/10
147 2010-02-12 02:53:00 48 Love Apple Soup
148 2010-01-28 02:54:46 47 Stahl's 411 e-newsletter for January 25-30
149 2010-01-20 02:47:03 46 It's the first week of Spring...
150 2010-01-07 01:53:24 45 Let it S....
152 2009-12-10 23:55:02 43 Thank You!!
153 2009-12-04 01:47:53 42 Need more toys!
154 2009-11-27 21:09:11 41 We're still thankful
155 2009-11-19 07:23:54 40 Gobble, gobble!
156 2009-11-13 07:13:41 39 Thank you!
157 2009-11-02 21:57:09 38 Free Soup!
158 2009-10-23 22:45:37 37 Short & Sweet
159 2009-10-16 20:54:16 36 Good news/bad news
160 2009-10-09 00:31:46 35 "The in her death throes, summer...
161 0000-00-00 00:00:00 34 No autographs, please
162 2009-09-25 05:25:17 33 Potayto, Potahto
163 2009-08-28 16:47:20 31 They're Baaaack!
164 2009-08-07 17:23:54 30 Stahl's 411 e-newsletter 8-7-09
165 2009-07-30 11:33:10 29 Holy Lazy Baker, Batman!
166 2009-05-30 00:29:36 28 W00T!
167 2009-05-15 12:22:32 27 Merry Hippie Christmas!
168 2009-05-07 00:18:05 26 Psssst.....Hey Kid!
169 2009-04-30 23:33:00 25 Stahl's 411 newsletter 4/30/09
170 2009-04-22 07:50:10 24 Stahls 411 ~ E-newsletter for 4/21/09
171 2009-04-08 00:59:54 23 Stahl's 411; April 6, E-newsletter
173 2009-03-11 23:47:02 21 An Ounce of Prevention...
174 2009-03-03 17:34:53 20 Don't cry...
175 2009-02-19 02:51:23 19 Tomato Bisque and a sled
176 2009-02-12 01:33:21 18 Who loves ya, baby?
177 2009-02-04 23:07:08 17 Ice!
178 2009-01-28 00:05:44 16 Taste the Music!
179 2009-01-14 10:16:53 13 How to stay warm...
180 2009-01-07 21:54:42 12 Break's Over
182 2008-11-20 00:47:57 10 Stahl's Bakery E-news November 20, 2008
183 2008-10-24 22:45:53 9 Stahl's Bakery E-news October 24, 2008
184 2008-09-20 00:01:04 8 Here comes the sun....
185 2008-09-12 23:21:19 7 Stahl's Bakery E-news ~ Sept. 13, 2008
186 2008-08-28 22:55:19 6 Stahl's Bakery E-news August 28, 2008
187 2008-06-26 22:49:14 5 Did you notice...?
188 2008-06-12 21:36:31 4 Holy Cannoli!!
189 2008-06-05 21:11:31 3 Farmers Market
190 2008-04-30 21:08:56 2 Stahl's Bakery E-news ~ April 30, 2008
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Q: How to detect if barcode scanner is attached to PC I am writing an application which detects if any bar-code scanner is attached to the pc or not. I don't know how to query the installed devices to check for barcode scanners. I am using C# and .NET 4.0.

A: Some barcode scanner are attached by keyboard wedge (Or their drivers report them as keyboards) - I believe there is no way to test if these are present.
Other specific scanners may be accessible through their USB ports but any status query will have to be on a model by model basis.

A: You probably want to use WMI...
Heres some CodeProject links that might help.
http://www.codeproject.com/Articles/18268/How-To-Almost-Everything-In-WMI-via-C-Part-3-Hardw
http://www.codeproject.com/Articles/21503/Hardware-Helper-Library-for-C

redpajama_set_name: RedPajamaStackExchange


At the Association Démocratique des Femmes du Maroc (ADFM), and as part of our ongoing support to the Soulaliyate women in their battle for equality and citizenship, we are appalled by the incomprehensible approach adopted by the regional authorities, which validates this decision under the guise "that the collectivity approved discrimination". We deplore the failure of competent authorities to deal efficiently and immediately with this matter, which not only is a serious regression on the gains made towards recognizing Soulaliyate women's rights in Morocco, it is also affecting the lives of 267 women from the community as well as their families.
In response to this situation, we call on the Minister of Interior in charge of the collective land to take urgent and immediate action to remedy this situation and address the harm suffered by women in Rhaouna, as provided by the law.