text:
Modern Electronic Devices: An Increasingly Common Cause of Skin Disorders in Consumers
zaterdag, 09 juli 2016 - Categorie: Onderzoeken
Bron: mobile.journals.lww.com/dermatitis/_layouts/15/oaks.journals.mobile/articleviewer.aspx?year=2016&issue=05000&article=00002
Corazza, Monica MD; Minghetti, Sara MD; Bertoldi, Alberto Maria MD; Martina, Emanuela MD; Virgili, Annarosa MD; Borghi, Alessandro MD
Vol. 27 - Issue 3: p 82–89
From the *Dipartimento di Scienze Mediche, Sezione di Dermatologia e Malattie Infettive, Università di Ferrara; and †Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic University of Marche, Torrette, Ancona, Italy.
Address reprint requests to Monica Corazza, MD, Dipartimento di Scienze Mediche, Sezione di Dermatologia e Malattie Infettive, Università di Ferrara, Via Savonarola 9, 44121 Ferrara, Italy. E-mail: czm@unife.it.
The authors have no funding or conflicts of interest to declare.
The modern conveniences and enjoyment brought about by electronic devices bring with them some health concerns. In particular, personal electronic devices are responsible for rising cases of several skin disorders, including pressure, friction, contact dermatitis, and other physical dermatitis. The universal use of such devices, either for work or recreational purposes, will probably increase the occurrence of polymorphous skin manifestations over time. It is important for clinicians to consider electronics as potential sources of dermatological ailments, for proper patient management. We performed a literature review on skin disorders associated with the personal use of modern technology, including personal computers and laptops, personal computer accessories, mobile phones, tablets, video games, and consoles.
With increasing use at work, home, and school, modern technology is increasingly involved in several dermatological conditions. These skin manifestations will probably increase over time with the use and pervasive popularity of electronic devices. Early recognition of the offending agent and its removal usually allow effective management.
We performed a literature review on cutaneous manifestations associated with the personal use of modern technology, including personal computers (PCs) and laptops, PC accessories, mobile phones, tablets, video games, and consoles.
A comprehensive search for articles in the PubMed database was conducted. Bibliographies of all included studies were also reviewed to find additional studies not included in previous research.
The key words used were as follows: dermatitis, electronic devices, modern technology, contact dermatitis, cutaneous manifestations, PlayStation, PCs and laptops, PC-accessories (such as mouse and mouse pad, keyboard, and keyboard pad), mobile phones, tablets, video games, and console. We included all types of articles.
Search results were categorized as follows: (1) video games; (2) PC, laptop, and computer accessories; and (3) mobile phones and tablets. For each category, we summarized the dermatological conditions related to the use of the device (Table 1).
mobile.journals.lww.com/dermatitis/_layouts/15/oaks.journals.mobile/imageviewer.aspx?image=/Original.01206501-201605000-00002.TT1.jpeg
Video Games–Related Dermatoses
Intensive video gaming has been associated with the occurrence of various cutaneous conditions arising from repeated trauma to the skin caused by the continuous use of video game controllers or by abnormal positions.5 A recent survey has found that the average time spent playing video games in a sitting position is increasing59; this aspect is linked to conditions that are not really dermatological such as deep vein thrombosis and increased risk of thromboembolism.
Over the last few years, the release of a video game console with a motion sensitive control system (Nintendo Wii) has caused a new spectrum of video games–related pathology, not linked to immobility but to strong physical activity, especially in untrained or unfit people.
PlayStation Thumb
PlayStation thumb is a repetitive strain injury, usually observed in children and young people, caused by continuous playing of PlayStation games. Repetitive strain injuries are conditions affecting the arms and hands due to repeated movements that damage tendons, nerves, muscles, and other soft body tissues.60 Several jobs, sport activities, and the playing of musical instruments can lead to this kind of injury as well.
The first case of PlayStation thumb, described in 2004,61 has been followed by other case reports and case series.1,60,62
Typically, PlayStation thumb manifests as pain and blisters located exactly on the site of recurrent pressure and friction with the controller of PlayStation, particularly on the thumbs and on the tips of the thumb, even though the involvement of other fingers, sometimes with nail alterations such as onycholysis, has also been reported.1,2 Other possible associated symptoms include pain, stiffness, swelling, numbness, and tingling of the hands, wrists, elbows, shoulders, back, or neck. Dermoscopy on PlayStation thumb shows typical hyperkeratosis and punctate hemorrhages.62 More recently, a parallel-ridge pattern with "pebbles" on the ridges, observed on dermoscopy, has lead some authors to suggest the probably more appropriate term of "PlayStation fingertip" to describe this condition.2
PlayStation Palmar Hidradenitis
To date, only 1 case of PlayStation palmar hidradenitis has been described in literature in a 12-year-old girl.3 It was an acute, painful hand dermatitis characterized, on physical examination, by erythematous, firm and highly tender nodules on the palmar surfaces of the hands. The lesions appeared after she had started to play with a new video game on the PlayStation for several hours a day. The diagnosis of palmar eccrine hidradenitis was confirmed by histopathological examination showing neutrophilic infiltration of the eccrine sweat glands in the absence of infectious agents.3
Frictional Hyperkeratosis (Callus)
The term knuckle pad refers to a fibrous hyperkeratotic plaque, usually round in shape, due to repetitive trauma. The first and only report of a knuckle pad induced by intensive video gaming was described in 2006 by Rushing et al.4 They reported a single fibrotic lesion localized on the right second distal interphalangeal joint of a 13-year-old adolescent boy previously treated for a wart without improvement. Biopsy revealed hyperkeratosis, acanthosis, and increased vascularity and fibroblasts. This thickening of the skin was provoked both by anchoring the video game controller and by video gaming several hours a day. In children, knuckle pads can be idiopathic, inherited in association with an autosomal dominant disorder, but more frequently lesions can be acquired by repetitive actions that traumatize the skin. While the classical causes of knuckle pad are cracking or picking or chewing fingers,4 playing video games may be an additional modern cause.
Contact dermatitis (CD) caused by the use of video game controllers is uncommon and probably underreported.
A possible case of hand eczema caused by a video game controller (Sony PlayStation One) was described in a 34-year-old female1; for work-related reasons, she spent several hours a day playing with a Sony PlayStation One controller in her hands. Patch testing revealed positive reactions for nickel (+++) and cobalt (++). As the manufacturer did not provide the composition of the controller and chemical analysis of the scratched material from the controller was not performed, the diagnosis of allergic CD caused by a metallic part of the video game controller is not incontestable. However, a prompt resolution of the palmar eczema was observed when she stopped the contact with the electronic device. Certainly, the local environment, such as moist and warm conditions as well as sweating of the hands, may accelerate the occurrence of CD, especially by intensifying the penetration of allergens into the skin.
In patients with a history of atopic dermatitis and intensive video gaming, the development of hand allergic CD should be suspected in the case of worsening of their eczema or loss of responsiveness to therapy. Nickel contained in a central "silver" button of the Xbox controller, positive tested by dimethylgloxime (DMG spot test), was the cause of atopic dermatitis exacerbation due to a superimposed allergic CD in a 9-year-old atopic boy.63
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Principal team owner Bill McGuire speaking about the stadium design at Wednesday's press conference.
A soccer-specific stadium — once written off as dead (or at least unlikely) — took two big steps toward reality Wednesday.
First, initial architectural renderings of the proposed stadium were released by the owners of Minnesota United, the group that has been given the rights to bring a Major League Soccer expansion team to the Twin Cities. The second step was the approval by the Metropolitan Council of a lease between the transit agency and the city of St. Paul.
There are many steps remaining, of course. But after a false start in Minneapolis, a flirtation with St. Paul that was considered by some a ruse, and the ultimate selection of the capital city as the stadium's host, the MLS franchise and new stadium seem assured.
Minneapolis may get to host the team for one season if the franchise begins play in 2017, as some MLS officials would prefer. But the long-term home will be in St. Paul. That was reinforced with a well attended press conference at the former Minnesota Club in downtown St. Paul, where the renderings were unveiled to the public.
The plans, prepared by Populous, one of the world's primary stadium designers, shows a modernist structure, glowing white and wrapped in a thin, translucent polymer skin. Principal team owner Bill McGuire said the skin will be equipped with LED lights that can change color depending on the events inside. The stadium itself would be sunken down 16 feet below grade to reduce its apparent height to between 70 and 75 feet.
Though the field itself will be uncovered, a canopy will protect most — but not all — fans from the weather. The inside of the stadium will feature a traditional soccer seating setup: square and snuggled close to a grass playing surface, with a large standing section in the south end, behind one of the goals.
Proposed stadium design viewed from the south east.
The stadium cost was estimated by McGuire to be "a lot, $150 million or more." That is compared to earlier estimates of $120 million. And it will seat upwards of 23,500 supporters, including the 3,000 spaces in the standing section. "Our conceptual idea was to bring a facility to the community that could stand up to what anyone thought was a great and wonderful facility," said McGuire.
As per the ownership group's pledge, the team will pay to build, operate and maintain the stadium, even though it will be given to the city once completed.
Interior view of the proposed stadium, shown from the south.
McGuire, a former CEO of UnitedHealth Group, was joined at the announcement by St. Paul Mayor Chris Coleman.
Coleman estimated that the taxes that would be collected when the redevelopment of the RK Midway is completed could be 10 to 12 times what is collected on the property currently. The St. Paul City Council will consider a development agreement between the city and the team at its meeting next Wednesday.
In addition to the stadium plans, development plans for the remainder of the 35-acre site were also unveiled. Rick Birdoff, who owns the '60s-era shopping complex known as RK Midway, showed what he hopes it will become: a mixed-use neighborhood of midrise buildings in lieu of the big-box stores and fast-food outlets that now occupy the property at the intersection of University Avenue and Snelling Avenue.
At the center of the development — stretching from University Avenue to the entrance of the stadium — would be two large parks that would remain open space. City officials said Wednesday it is possible that at a later date the park land would be given to the city but still maintained by the team and Birdoff. There is also a possibility, said city Finance Director Todd Hurley, to eventually exempt that portion of the site from property taxes. As of now, the city will ask the Legislature to exempt only the land beneath the stadium. In addition, the city will ask lawmakers to exempt the project from sales taxes on construction material and to provide a liquor license to the stadium.
The release of the renderings comes 11 months after the announcement that Major League Soccer had awarded an expansion franchise to Minnesota United. That announcement was made at Target Field in Minneapolis, near the site initially proposed for the site of a new stadium, the Minneapolis Farmers Market.
That deal fell apart — or never actually came together — after opposition from Minneapolis Mayor Betsy Hodges to the two tax breaks sought by the team. There was also a lukewarm-to-hostile reaction from state legislative leaders.
Aerial view of the proposed soccer stadium design.
The team's attention turned to St. Paul as early as May of 2015. After visits from to league officials, the announcement for a tentative deal to play in St. Paul was made Oct. 23. Putting the land deal and construction agreement together led to a three-government arrangement involving the Port Authority of St. Paul, the city and the Met Council, with the Federal Transit Administration and the state playing supporting roles.
That deal received its first approval Wednesday when the Met Council moved forward with finalizing a long-term land lease with the city. In a Monday briefing about the terms of the lease, Met Council's Lucy Ferguson Galbraith said the land deal is structured to ensure that the property continues to benefit transit. The lease of the land — purchased with Federal Transit Administration grants — will be for 50 years with lease payments of $556,620 a year.
Proposed stadium design viewed from the south west.
The long-term lease will actually be between Met Council and the City of St. Paul. The city will in turn enter into a shorter-term sublease with the owners of the team. Once the stadium is built, it will be owned by the city. Senior city officials have said the team will make lease payments to the city, which will in effect be reimbursed for the rent it will pay to the Met Council.
According to the deal between the Met Council and the city, the rent will begin being charged on April 1 of this year, but will not be paid until the first game is played in the new stadium, sometime in the early spring of 2018.
Galbraith said the Met Council will cover no ongoing costs on the stadium site but will be responsible for environmental remediation on the land, which was used as a bus-storage and maintenance facility until 2002, and has since been used for construction staging for the Green Line light rail line and the A Line bus rapid transit service.
The cost of that environmental cleanup, capped at $4.5 million, will be shared with the city, which will cover up to $1.5 million of the costs. Both governments hope to be at least partly reimbursed from state and federal environmental cleanup grants, Galbraith said. The Port Authority of St. Paul will serve as the project manager for the remediation work.
A recent change in plans for the stadium has moved its location slightly to the east and the north, onto land now owned by Birdoff. According to pending agreement between the team and the city, Minnesota United will purchase the land it needs from Birdoff and give it to the city.
View of the proposed stadium design from Interstate 94.
Birdoff said Wednesday he also will seek to sublease from the city land on the western edge of the bus barn site, along Snelling, for additional commercial development. That land would not be part of the city's request for tax exemption and would be required to pay so-called PILOT taxes (payment in lieu of taxes), which are equal to what would be paid if the private building was on private land.
Birdoff quipped about the complexity of the transactions needed to put the project together. "It's a lawyers' dream," he said.
Proposed stadium design viewed from the south.
He expects the first development to be an office building with ground-floor retail at the corner of Snelling and University Avenues. He said United Property, whose owners, the Pohlads, are also part of the team ownership group, will likely be involved in that development. The building will not be built until tenants are lined up, Birdoff said, but that there is interest in the project from them.
On Monday, the City of St. Paul issued something called the Scoping Environmental Assessment Worksheet, which sets out what will studied as part of the environmental review of both the bus barn and the shopping center. People can submit comments suggesting additional development scenarios and other issues that should be studied.
Submitted by Bill Spankerton on 02/25/2016 - 02:07 pm.
This seems like a reasonable ask, but I'm concerned the legislature will shoot it down in an attempt to "redeem" itself after being hoodwinked by the Vikings/NFL.
Submitted by Hugh Jass on 02/25/2016 - 03:03 pm.
Congrats, MN United. Beautiful stadium!
Submitted by Edward Blaise on 02/25/2016 - 03:48 pm.
Can we add a picture of the run down warehouses that Bike Lane Betsy saved by driving this free stadium away from her city?
Submitted by Frank Phelan on 02/25/2016 - 05:36 pm.
Not known as business socialism Betsy.


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Home FEATURED End of the road for giant matatu insurer
End of the road for giant matatu insurer
Underwriter was brought down by huge fraudulent claims.
The Insurance Regulatory Authority (IRA) has resolved to wind up Blue Shield Insurance in a move that could close the curtain on what was once Kenya's biggest underwriter of public service vehicles.
Blue Shield was placed under statutory management on September 16, 2011 after several years of complaints by clients whose claims had been delayed.
The firm was the biggest insurer of PSVs – matatus and motorcycles – by the time it was taken over by the regulator. The underwriter's life insurance arm-Shield Assurance-was acquired by British firm Prudential Plc for Sh1.5 billion in 2014.
A special IRA meeting held on Monday resolved to wind up Blue Shield, but shareholders of the collapsed insurer yesterday filed an application seeking to stop the regulator's move. The shareholders claim the winding up is a ploy by the Commissioner of Insurance Sammy Makove to defeat ongoing investigations into alleged embezzlement of funds by IRA officials and receiver managers of the company.
The shareholders claim that criminal investigations detectives are seeking to arrest receiver managers of Blue Shield Insurance and IRA commissioners over diversion of Sh200 million from the collapsed underwriter.
The Directorate of Criminal Investigations (DCI) has sought the help of Auditor General Edward Ouko in tracing evidence to support its case.
The detectives believe that the receiver managers and IRA officials have pilfered money collected as rent from the troubled insurer's Blue Shield Towers in Upperhill since 2011.
Blue Shield's shareholders have made the claims in court. The shareholders have filed as evidence a letter from the DCI to Mr Ouko seeking assistance in gathering evidence.
The letter from the DCI indicates that detectives are seeking to prosecute Blue Shield's statutory manager John Keah and unnamed IRA commissioners.
Also to be prosecuted are finance chiefs of two state agencies; the Kenya National Highways Authority (KeNHA) and Kenya Rural Roads Authority (KeRRA) that are tenants at Blue Shield Towers.
"The matter was reported to CID headquarters on February 2, 2016 for investigation. In order for us to prosecute the statutory managers we are requesting your office to audit the documents already in our possession.
We suspect IRA commissioners, statutory managers and financial heads for KeNHA and KeRRA have colluded to defraud shareholders," the letter from the DCI reads in part.
The letter from the DCI to Mr Ouko does not identify which IRA commissioners it is probing. The shareholders' application against winding up Blue Shield comes as the IRA seeks to extend the receiver manager's term that was set to expire today (April 20, 2016). The extension is aimed at allowing the regulator time to commence winding up proceedings.
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Business Daily is Kenya's only daily business newspaper published by the Nation Media Group. The newspaper, launched in March 2007, is published from Monday to Friday, with the Friday edition circulating over the weekend. It is based at the Nation Centre in Nairobi.

redpajama_set_name: RedPajamaCommonCrawl


text:
Il trigger (traducibile come innesco) è un circuito elettronico presente in tutti gli oscilloscopi, ha la funzione di sincronizzare la partenza della scansione orizzontale con un preciso livello di soglia del segnale periodico da analizzare. La sincronizzazione, similmente ad un "fermo immagine" permette la visualizzazione stabile sullo schermo del segnale in analisi.

Funzionamento
Il segnale di trigger viene generato nel circuito del preamplificatore verticale durante il passaggio del segnale in analisi. È costituito da un breve impulso di tensione che nasce nel preciso istante in cui il livello del segnale periodico in transito coincide con quello impostato dall'operatore; questo impulso è inviato al circuito della base dei tempi e dà il via ad un segnale a forma di rampa (onda a dente di sega), il quale va a pilotare le placchette di deflessione orizzontale, ovvero avviene la partenza con velocità costante del punto luminoso costituente la traccia. Nel frattempo il segnale in analisi sta transitando nel relativo lungo percorso costituito dalla linea di ritardo, (concettualmente, un lungo e sottile filo metallico avvolto a spirale), posta tra il circuito preamplificatore e l'amplificatore finale verticale, la sua funzione consiste appunto nel ritardare l'arrivo del segnale da analizzare alle placchette verticali, non prima della partenza della scansione orizzontale, solo in tal modo risulta possibile visualizzare interamente i veloci fronti di salita di un'onda quadra o di un impulso di tensione.

Gli inventori del circuito sono Howard Vollum e Jack Murdock, fondatori nel 1946 della società Tektronix.

In origine il settaggio si impostava con leve, manopole e pulsanti; negli strumenti moderni, di qualsiasi fascia di prezzo siano, esso si imposta tramite appositi menu.
Nel caso non si entri nel menù di trigger, esso è preimpostato in modo automatico, con inizio di visualizzazione al valore medio del segnale d'ingresso, sul fronte positivo del segnale; nel caso d'impostazione manuale, rimane memorizzata l'ultima impostazione eseguita.

Voci correlate
Oscilloscopio
Trigger di Schmitt
Onda a dente di sega

Circuiti elettronici
Dispositivi elettronici

redpajama_set_name: RedPajamaWikipedia


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text:
Smith Brothers Cough Drops
We are sad to announce that Smith Brothers Cough Drops have been discontinued by the manufacturer. Please consider Luden's Cough Drops or Pine Brother's Cough Drops.
Smith Brothers Cough Drops History
The Smith Brothers Cough Drop box portrays one of the world's most famous trademarks. The two bearded gentlemen are affectionately known to generations as Trade and Mark. Not well known, however, is the fact that the Smith Brothers really existed. Their names were William (Trade) and Andrew (Mark) and they helped found Smith Brothers in Poughkeepsie, New York in 1847.
William and Andrew were sons of James Smith who moved to Poughkeepsie from St. Armand, Quebec in 1847 to establish a restaurant. Though James was a fine carpenter by trade, he was an even better candy maker and a businessman. The story of the birth of the first Cough Drop is a good example.
The story goes like this... a journeyman stopped at the Smith restaurant and sold James the formula for a delicious and effective cough candy. James saw a need for such a product in the cold part of the country where he lived and immediately mixed up a batch on his kitchen stove.
Smith Brothers Cough Drops were a quick success and demand for the "cough candy" grew fast. Only a few years later, in 1852, the firm's first advertisement appeared in the Poughkeepsie paper, inviting all "afflicted with hoarseness, cough or colds" to test it.
Young William and Andrew were active in the new business from the start. They helped mix the family secret formula in their father's kitchen and busily sold the product in the streets of Poughkeepsie. The two boys inherited the fast growing business on the father's death in 1866, and the company officially became known as Smith Brothers.
As sales grew their success was met with a whole flurry of imitators -"Schmitt Brothers", "Smythe Sisters" and even other "Smith Brothers" appeared with imitative product. The real Smith Brothers, by this time having long, flowing beards, decided to place their own pictures on their product packaging, which consisted of glass bowls for a counter display and small envelopes into which the shopkeeper counted the Smith Brothers Cough Drops for each sale.
By chance, the word "Trade" appeared under the picture of William and the word "Mark" under that of Andrew. Thus, it happened by a mere coincidence that the famous Smith Brothers' trademark was born and the Smith Brothers became known to generations of Americans as Trade and Mark.
Smith Brothers Cough Drops Memories
My grandma would buy a box of these every Sunday before church. We would sit together and share them during the service. I am 43 now and she is 90. We can't find these in our town anymore. I plan to buy a box and slide in next to her at church. It is fun to think after all these years of her spoiling me, I can spoil her a little bit. she will be so surprised when I pull a box out of my purse and hand them to her. I may not get the box back! ~Denise from Kentucky


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ellie be: storyteller + photographer : 2013.
Have you ever had those moments where you say something in an effort to encourage a friend, and then all of a sudden you realize that you need that reminder as well? It's this weird feeling of, "Gosh, did I actually say something that made sense?" and "Wow, maybe I should take my own advice."
That happened to me recently. And it's crazy how those words have rung true for me in so many ways. I hate tooting my own horn (such a weird phrase) and trust me, I'm not doing that here. I'm just saying how ironic it is when sometimes the words you need to hear most, come from yourself. So so strange.
2012 was an amazing year. One filled with tears, laughter, joy and sorrow, heartache and happiness. I was stretched and changed and broken and restored. You all saw me go to Guatemala. I shot a proposal. I turned 18. And all the while, I learned something. Trust is a difficult thing.
You see, trust was my "one word" for 2012. And I had faith that God was going to run with it, and that He did. I learned to lean on Him more than I ever have before. And it was amazing. And exhausting. And so so good for my soul.
So I thought long and hard about my word for 2013. I prayed about it and went through so many words. I mean COME ON THE ENGLISH LANGUAGE IS EXTENSIVE. I almost chose "cute" for the new year's word. #kidding.
Free: enjoying personal rights or liberty, as a person who is not in slavery.
I'm definitely not done learning about trust. I have so much more to learn about my God and about trusting him completely and fully. But I get excited when I think about living in freedom.
Freedom is ignoring fear of man and living the life that you have been created to live. It's loving others without fear and loving God with everything you are. Freedom is knowing that God has a brilliant plan for your life and "every little thing is gonna be alright." It's being your beautiful self with all of your wonderful gifts and talents and quirks and personality. It's being there for others and giving of yourself in love. It's enjoying life and all of it's beautiful-ness and being free to cry when things get sad. Freedom for me is being free to lose because I have won everything in Christ.
Being free is letting go of somethings that have been clinging closely to you and dragging you down from what you could accomplish. And that's important. I can't hold on too tightly to what is in the past because it keeps me from the future.
And that's my 2013. And I'm pretty excited about it.
ps. I am doing so much traveling this next month and I am excited to share it all with you. Much love.
I love you. You are so wonderful. And I love your word. 2013 is going to be SO (to quote my mom) EXCITERATING.
This reminds me of the song "Free" by Ginny Owens :-) The words are so so sweet.
God has been teaching me about making myself free of hurt from past grievances. We are free to love and forgive because of the great love and forgiveness we have been given!
love everything about this post, how powerful. happy new year ellie be!
I am ready for 2013!!:) Awesome post Ellie Be!!
O.M.G. This post earned a favorite in my "book of favorites". Your words are so incredibly beautiful! I wish I could have that talent, free is a good word for 2013. I might try this. Um, how bout the word- no. (No, not no) Probably authentic or adventurer. I think both although I don't know which one I'll choose.
Hopefully your travels will be fun! I hope I'll have some fun with all of my amusement park thrills!
Ellie -- I'm so glad to have met you, gotten to know you a little, and followed along here on your blog this year. You're such a sweet girl and I've been really inspired through your posts and photography. I love how you've joined in with many others in choosing "one word" for the year. It's always really neat to see how it's integrated into your year. Happy 2013; hope it's fantastic! xoxo.
Love this -- all these posts about 2013 are making my heart all excited. Can't wait to see what's going to happen in 2013 for you, dear!
Oh my goodness. I just found your blog through Bleah's,and I LOVE IT! You had me at the words "yellow" and "chocolate".*big grin* Both your guest post on her blog and this post on yours are great!
Wow, wow, wow!!! You have a great way with words, Ellie. This post and the one after this one are both really encouraging. Thank you!


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/ Portrait - NPG D39295; Vanity Fair Panel no. 5 (includes John...
Vanity Fair Panel no. 5 (includes John Francis Holcombe Read; Sir James Porter Corry, 1st Bt; Arthur Wellesley Peel, 1st Viscount Peel; Oscar Browning; Spencer Compton Cavendish, 8th Duke of Devonshire; Nathaniel Mayer ('Natty') de Rothschild, 1st Ba...)
4 of 4 portraits of Sir William Cuthbert Quilter, 1st Bt
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by Liborio Prosperi ('Lib'), and Carlo Pellegrini, and Sir Leslie Ward, and 'Hay', and Théobald Chartran ('T')
chromolithographs pasted onto wooden panel, assembled from prints published 1881-1889
13 1/8 in. x 55 in. (333 mm x 1397 mm) image size
Théobald Chartran ('T') (1849-1907), Painter and caricaturist. Artist associated with 86 portraits.
'Hay' (active 1888-1893), Cartoonist. Artist associated with 18 portraits.
Carlo Pellegrini (1839-1889), 'Ape'; caricaturist. Artist associated with 490 portraits, Sitter in 5 portraits.
Liborio Prosperi ('Lib') (1854-1928), Cartoonist in Vanity Fair. Artist associated with 65 portraits.
Sir Leslie Ward (1851-1922), 'Spy'; caricaturist and portrait painter; son of Edward Matthew Ward. Artist associated with 1617 portraits, Sitter in 9 portraits.
Sittersback to top
Prince Albert Victor, Duke of Clarence and Avondale (1864-1892), Eldest son of Edward VII. Sitter in 117 portraits.
Frederick Archer (1857-1886), Jockey. Sitter in 13 portraits.
George Alexander Baird (1861-1893), Amateur rider; landowner. Sitter in 3 portraits.
(Colin) George Barrett (1863-1898), Jockey. Sitter in 3 portraits.
Sir Edward Bates, 1st Bt (1816-1896), Shipowner and politician. Sitter in 2 portraits.
Frederick George Brabazon Ponsonby, 6th Earl of Bessborough (1815-1895), Politician and cricketer. Sitter associated with 3 portraits.
Oscar Browning (1837-1923), Historian, teacher and linguist. Sitter in 2 portraits.
Alan Frederick Cathcart, 3rd Earl Cathcart (1828-1905), Soldier and agriculturalist. Sitter in 7 portraits.
Wellington Henry Stapleton-Cotton, 2nd Viscount Combermere (1818-1891), Soldier and landowner. Sitter in 2 portraits.
Sir James Porter Corry, 1st Bt (1826-1891), Politician; MP for Belfast and Mid Armagh. Sitter in 2 portraits.
Spencer Compton Cavendish, 8th Duke of Devonshire (1833-1908), Politician and Captain; ex-officio Trustee of the National Portrait Gallery. Sitter in 56 portraits.
John Dillon (1851-1927), Nationalist and politician, leader of the Irish Parliamentary Party. Sitter in 9 portraits.
William Ewart Gladstone (1809-1898), Prime Minister and writer; Trustee of the National Portrait Gallery. Sitter associated with 321 portraits.
Sir Charles Hall (1843-1900), Recorder of London. Sitter in 10 portraits.
John Hargreaves (1839-1895), Master of the Cattiscott Hunt. Sitter in 3 portraits.
James Leigh Joynes (1824-1908), Clergyman and schoolmaster. Sitter in 2 portraits.
Henry Matthews, Viscount Llandaff (1826-1913), Lawyer and politician. Sitter in 7 portraits.
Sir Morell MacKenzie (1837-1892), Physician and laryngologist. Sitter in 3 portraits.
George Charles Spencer-Churchill, 8th Duke of Marlborough (1844-1892), Writer. Sitter associated with 4 portraits.
John Howe Osborne (1833-1922), Jockey and trainer. Sitter in 4 portraits.
Lord Alexander Victor Paget (1839-1896), Naval officer and Deputy Lieutenant of Staffordshire; son of 2nd Marquess of Anglesey. Sitter in 4 portraits.
Arthur Wellesley Peel, 1st Viscount Peel (1829-1912), Speaker of the House of Commons; Trustee of the National Portrait Gallery. Sitter in 24 portraits.
Sir William Cuthbert Quilter, 1st Bt (1841-1911), Art collector and politician. Sitter in 4 portraits.
John Francis Holcombe Read, Stockbroker. Sitter in 3 portraits.
Nathaniel Mayer ('Natty') de Rothschild, 1st Baron Rothschild (1840-1915), Merchant banker. Sitter in 4 portraits.
Henry John Brinsley Manners, 8th Duke of Rutland (1852-1925), Politician, army officer and landowner. Sitter in 8 portraits.
Sir Partap Singhji, Maharaja of Idar and Regent of Jodhpur (1845-1922), Indian ruler and army officer. Sitter in 9 portraits.
Savile Brinton Crossley, 1st Baron Somerleyton (1857-1935), Politician and company chairman. Sitter in 10 portraits.
Benjamin Disraeli dies of bronchitis. He refuses a state funeral and is buried next to his wife, Mary Ann Viscountess Beaconsfield.
Gladstone's Irish Land Act is passed in a bid to stop violence carried out by the republican Land League, conducted in protest at the 1870 Land Act.
Henry Mayers Hyndman forms the Marxist Democratic Federation.
The Natural History Museum is opened on Exhibition Road, South Kensington. The museum, a landmark gothic design by the architect Alfred Waterhouse, was built to house specimens from the natural sciences, previously in the British Museum's collection. Today, the museum comprises of over 70 million items, and is a world-renowned research centre.
Alexander II is assassinated in a bomb attack by members of a left-wing revolutionary movement. He was succeeded by his son, Tsar Alexander III.
US President James Garfield is shot by Charles Guiteau.
The first Anglo-Boer war ends. The war is started by a Boer uprising, as the British had annexed the Transvaal in 1877. Following Britain's defeat at the Battle of Majuba Hill, a truce is signed giving the Boers self-government and later independence.
Do, draw and make!
From building dens to food faces – enjoy our Playful Portraits activities and find out about some brilliant people!
Activities for children and families inspired by three healthcare heroes from our Collection.
Downloadable and web based resources to support learning at home linked to art, history, citizenship and literacy.
Get learning
Silhouettes display, 2004-05
Commonwealth Trail
Adopt-a-Portrait
Men of the day: Caricatures from Vanity Fair
Later Victorian Portraits Catalogue
Conquering England


text:
Q: When not using VS designer, should I add code to Form1.designer.cs? I am not sure about that. I do not want to use designer for many things (but for some I do). Should I write my "manual" code into the designer.cs or to form class itself?

A: No, never.
Because it will be generated again and your written-code will be lost.
In order to add code to a class which has designer, you need to define a partial class with the same name.
public partial class Form1
{
    // here write your logic (which will be preserved).
}

For more info: Partial Class (C#)

A: You should really not do that. Each time you change something in the designer, it will regenerate the InitializeComponent() method. Therefore, your changes will be overwritten by that code. The only way this would not happen is to write your code in the same way the designer does - which is almost impossible. It could also happen that your designer crashes after you changed the code and you may not know why. You should better stick with the designer.

redpajama_set_name: RedPajamaStackExchange


We care to help students and young people, define their route, grow and develop into healthy and happy individuals.
We care to help their parents too in assisting their children!
We believe in the talent, the power, the goodness and the ability that each child or young person brings with them.
We make it our responsibility is to assist them to "open up to this", acknowledge their uniqueness and the availability of possibilities that lie ahead and to show them the way.
It is our strong belief that mentalities in Cyprus have to change, if we want our children to look at the future with optimism. They have to change if we want our future citizens to have a positive outlook on life and have the drive, the interest and the passion to contribute effectively to their society and engage in what they love and what they feel they can do best.


Your groomsmen will appreciate the quality of our classic-shaped, horizontal Cigar Pub Sign which is gloss-printed directly onto a cherry wood finish base for a everlasting cigar themed gift. Personalized with first name, last name and year established. Comes ready to hang and measures 9" x 12".


The Aqueduct documents are out — some released by Governor Paterson, some by the winners of the Aqueduct racino contract, AEG — and it appears that, during the bidding process, AEG kept goosing its upfront payment offer and predicted profitability until it qualified for the win.
"Our previous WPU numbers were very conservative and were baseline for budgeting purposes," says one AEG document from September. "We believe these [new] numbers more accurately reflect the market conditions and revenue potential that our group can bring to the State."As AEG has some connections with politicians, the presumption is that something funny is going on. The deal is being scoped by the state inspector general.
Paterson's office insists there were all sorts of factors that played into their decision — including "community support" and "minority- and women-owned business involvement," which will probably not appease folks who mainly wish to see the thing make as much money as possible for the state out of the poor fish who choose to feed their gambling addiction with it.
The Governor's office also says AEG was quickest on the draw, promising to have 3,000 video lottery terminals up and running in six months.
*Update: The bidder that couldn't come up with the $370 million was wrongly attributed and has been corrected.


Heavily laden trucks travel slowly. They are big and they get in the way. When there are two of them and one is trying to overtake the other it is almost certain to infuriate the drivers who get stuck behind.
Firstly, it takes forever because one lorry is travelling at 55 miles per hour and the other is travelling at 55.01 miles per hour. If the road is busy it means that two lanes are now blocked for the foreseeable future.
Then, once the two trucks are alongside each other, there's the extra delay whilst the trucker's code is enacted, that series of mysterious waves and gestures that nobody else is allowed to understand. Once complete, the overtaking truck then accelerates back to 55.01mph to complete the manoeuvre. Whilst all this is going on, you're stuck behind them in your BMW 5 series rapidly losing the will to live.
Having good lane discipline is all very well and good but when other drivers stick religiously to the middle lane as though their lives depend upon it, etiquette swiftly disappears out of the window.
Why do they do it? The inside lane is clear yet still they sit there, gripping the wheel and maintaining a steady 60mph all the while, behind them, a tailback is starting to form. The other guarantee in this situation is that if any other driver takes matters into their own hands by under-taking, they will receive the most withering glare the brainless lane-hog can possibly muster.
People have to use the phone, we understand this. Mostly they are conscientious enough to do it safely by using the right equipment. It's still really annoying though, because once they're busy on the phone, attention to speed becomes almost non-existent. One moment they're doing a steady 70, the next they're down to 55 as their attention waxes and wanes and you have to pull out to overtake them. No more than two minutes later, they will come back past you doing 80 before starting the whole game over again.
It's the kind of mobile hazard that used to feature regularly in those retro racing games but that has no place on the motorway. Utterly infuriating!
Any driver who discards half-eaten food out of their window so that it hits the car behind them should be made to suffer. A half-eaten hamburger, sandwich crusts, cigarette butts, plastic packaging…nothing is off limits for the litter louts.
Not only is it a safety hazard, but it is also the reason why the roadsides are covered in the stuff. Just keep it in the car until you can dispose of it properly!
Some drivers seem to think that mirrors are just for checking their hair. After all, the manufacturer's kindly provision of three mirrors allows them to check every aspect of their profile. Often they will do this whilst overtaking but what they almost certainly will not do is check their mirrors before pulling back in again, forcing you to jump on the brakes and shake your fist at them. Naturally they won't notice you shaking your fist at them because they don't know how to use their mirrors.
When it's raining, braking distances become longer. We all know this, so why are there so many drivers who think they can drive the same way in torrential rain and strong wind as they do on a calm, sunny day?
Or they approach behind and then drive so close that a collision is inevitable if you are forced to brake suddenly. I can only imagine that these people base their driving style on the weather conditions inside the car.
Having made the effort to get into the right lane in plenty of time, your serene progress is disrupted by a driver who desperately wants to shave another 0.3 seconds off of their journey by overtaking just one more car. Soon this has turned into a row of cars, and they've arrived at their exit on the opposite side of the road. The inevitable wild manoeuvre across all three lanes should be punishable with something exceedingly painful indeed.
This applies equally to the lane closure for road works. Two lanes of traffic have patiently siphoned into one. But there's always one driver who comes roaring along the now empty, and soon to vanish, lane and then has to cut in at the last moment bringing all other traffic to a virtual standstill as he does so.
With the Honda Civic hybrid, you can play a nice, eco-friendly game that whiles away the hours on long drives – simultaneously helping to save the planet!
The "game" is all about maximising miles per gallon. Because the Honda Civic hybrid uses both a traditional internal-combustion engine that runs on petrol – and an electric motor powered by a rechargeable battery, the gar is a good choice for today's green and thrifty motorists.
The way the car works is that the electric motor takes some of the strain when the car is accelerating or climbing hills, thereby saving petrol. The extra load, though, drains the battery, so the car cleverly recharges the battery when the car goes downhill or when it is decelerating.
The Civic also includes dashboard dials featuring real-time display of what's happening each second of your drive. Obviously, accelerating causes the miles per gallon to decrease but at a steady 60 miles per hour on a flat road, the car shows it is achieving up to 65.7 miles per gallon as the battery helps out.
On very long ascents, drivers are able to see the power being slowly drained from the battery as the mpg figures hold up well (when compared to conventional petrol-engine cars) from the additional electric propulsion.
On the downward slope, the battery is then recharged at no "cost" to the driver – ready to help out again on the next hill.
Hybrid cars are the logical next step for traditional motorists taking their first tentative steps into the world of eco-friendly motoring. The transition isn't a painful one by any means. Meanwhile, the "game" of maximising miles per gallon saves money, saves the planet, and makes those long journeys that bit less tedious.
After being unveiled at the Geneva Motor Show in March, Renault's limited edition Wind Gordini made it to UK showrooms this week. Limited to just 200 vehicles, the Wind Gordini comes with a choice of two petrol engines, the entry level 1.2-litre engine and a 1.6-litre engine. While the 1.2-litre version is capable of producing 100bhp, the 1.5-litre engine can produce 133bhp.
Although the limited edition Wind Gordini is virtually identical to the standard version of the car, there are a few cosmetic changes that set it apart. Along with 17-inch silver alloy wheels and Gordini badging on the car's side pillars, customers have the choice of three paint colours – blue, black or white – to go along with the distinctive stripes that adorn the car's exterior.
The car's interior features two-tone leather seats embossed with Gordini badges, blue and white door straps and a sport steering wheel. The car's gear stick is also adorned with the Gordini badge. Drivers are also given a reminder of the exclusivity of their car, as the Wind Gordini's interior also features a numbered plaque.
The limited edition model also comes with Bluetooth, climate control and USB connectivity as standard. On top of these features, a Thatcham alarm is also included.
Prices for the limited-edition Renault Wind Gordini stand at £15,195 for the 1.2-litre version and £16,095 for the 1.6-litre version. Both are available to order now.
As the prices for the Wind Gordini were announced, Renault also revealed a reduction in the price of the standard version of the car. The 1.2-litre Dynamique model will now cost customers £12,995.
Deciding what constitutes the best family car in the modern age is something that causes a surprising amount of heated debate.
Of course, a few factors are beyond dispute. All parents would agree that safety is absolutely paramount.
Then there's the matter of space. The amount of internal space and luggage space required will depend on the size of the family, the number of occasions you need to take wider family members such as grandparents on trips and the likelihood your children want to bring along their friends for the ride.
All are important considerations in deciding on the number of seats you'll need and just how important luggage space sis for you.
Many families opt for the five-plus-two car versions – whereby the car is a standard five-seater with two occasional pop-up seats in the boot space for the relatively rare occasions when six or seven seats are required.
The Honda FR-V is a relative rarity in the modern age having, as it does, three seats in the front making it an ideal choice for a family of four which has the occasional need for two additional seats.
For bigger families still, the MPV is often the only realistic option. Modern safety and seating requirements mean that parents the world over have become expert mini-bus drivers, steering their MPVs through small streets crowded with traffic – and usually built for a previous age of smaller vehicles.
For some families, performance, prestige, luxury and gadgets are all-important. An increasing number of car manufacturers now incorporate in-car entertainment systems as standard to improve those seemingly endless "are we nearly there yet?" journeys.
As for the kids, well such gadgets and getting one up on their peers are perhaps more important considerations for family cars than those of their parents!
Monday July 11th, 2011 17:11 Live A Little, Enjoy Yourself On An Experience Day!
Everyone knows boys love their toys, but women are hot on their tracks – race tracks that is – when it comes to driving experience days. Man or woman, who could pass up on the opportunity to drive a classic car for the day, or whizz around the course at Silverstone in a Ferrari 360?
The list of choices for driving experiences is endless. Always popular, supercars are a staple of this type of industry; fancy getting behind the wheel of a Lamborghini? How about an Aston Martin? A Porsche? Don't worry if you can't decide, try all three! If you prefer to get off the beaten track, try your hand at rally driving for a few hours or a full day, at courses all over the country. Specialist rally cars are custom made for the circuits and you can rely on the experience of the qualified instructors to make your day a memorable (and safe) one.
If you feel the need for more speed – and peril, you can try stunt driving at one of the many stunt schools, who are offering to teach you how to make hand break turns, J-turns, how to pop a wheelie, and probably improve your parking skills along the way. At some tracks, roving reporters bring a celebrity feel to the proceedings, and you can bet you're in safe hands with qualified, experienced stunt drivers.
For those wanting to experience something a little bit more unusual, Segway Safaris are a great day out, you can rent a lightweight Buggy and test the terrain, or – if you want to get off land altogether – take to the waterways on hovercraft for an hour or two.
Visitors attending last weekend's Goodwood Festival of Speed witnessed the debut of Honda's latest hybrid concept car – The highly anticipated MUGEN Honda CR-Z Hybrid Concept. Two concept models were on display, the Honda CR-Z MUGEN RR Concept and the MUGEN CR-Z Concept.
While the car retains the Honda IMA electric motor, the car's original 1.5-litre i-VTEC petrol engine has been rebuilt to MUGEN specification, with bespoke upgraded and strengthened internal components. The introduction of centrifugal forged-induction will help the CR-Z MUGEN to deliver over 50% more power and torque from the Honda's petrol-electric drive train. Power output for the car is in the region of 200bhp.
Although there are no official performance figures for the CR-Z MUGEN as of yet, early tests with a prototype car give the concept car a 0-62mph time of around 6.6 seconds. As there will be up to a 15% increase in power to come from the engine, and an approximate reduction in chassis weight of 50kg, expect overall performance figures to be even better than.
In terms of fuel consumption, Whittamore was encouraged by early tests in this area. Fuel economy ranges from 50+ mpg in 'eco' mode, and 35+ mpg when using the boosted power in the 'MUGEN' mode.
As for the Honda CR-Z MUGEN RR Concept, its appearance suggests it is more focused for track use. It has a unique front aerodynamic bumper, front fender, side spoiler, rear bumper, rear wing, and 18" wheels. The "RR" moniker was adopted in order to represent the racing spirit of MUGEN. Unlike the MUGEN CR-Z Hybrid Concept, performance details are currently unavailable.


A study conducted by the Ponemon Institute and sponsored by IBM shows growing recognition among C-titles executives of the importance of data protection.
Seventy-seven per cent of C-level executives in a 115-person survey conducted in the U.K. say their organization has experienced a data breach at some point and all of them report attacks targeting corporate data in the past 12 months.
These findings come from a study released on Wednesday by IBM, a company that sells data protection services, and The Ponemon Institute, a privacy and information management research organization.
Larry Ponemon, founder of the group that bears his name, said that survey shows a shift in the way C-level executives think about security software. Investing in data protection, he said, is now seen as less expensive than recovering from a data breach.
Data protection initiatives on average, according to the survey, result in a cost savings or revenue improvement of £11 million ($16 million) for organizations.
Perhaps more surprising than the revelation that security matters is the finding that while 75 per cent of respondents see the CIO as the person responsible for data protection, 82 per cent of respondents believe that the failure to stop a data breach would not result in the firing of the CIO.
This suggests either that respondents' beliefs about responsibility are misplaced or that few believe anyone can orchestrate a completely successful defense against cyber attacks, making firing for an inevitable outcome pointless.
As it turns out, the latter interpretation seems to be supported by the study: Over 27 per cent of the respondents doubted that their organizations could avoid a data breach in the next 12 months.
CEOs appear to be more confident than the broader set of executives questioned, with only 10 per cent expressing doubt about avoiding a data breach.
On a related note, CEOs appear to be less well-informed than other executives about the prevalence of online attacks.
"[O]nly 18 per cent of CEOs believe attacks on data happen hourly or even more frequently, while 34 per cent of other C-level executives believe this to be true," the study says.


August and September are always particularly busy months for us but this summer was exceptionally so! Most of our weddings take place in Southern England however we still manage to squeeze in a few international commissions each year. August saw my associate photographers Isabel and Graham document a charming wedding in rural France and then I had the pleasure of working with Nina and Michael in the picturesque Austrian town of Enns. It was probably around 35 degrees in the midday sun and without a cloud in sight, absolutely breathtaking.
We were absolutely delighted with Allister's coverage of our big day. We felt that he perfectly managed to convey the essence and overall atmosphere of the celebration. At the same time has a great and quick eye for details and situations and captured so many magic moments some of which we were not even aware of on the day and were absolutely stunned and pleased to discover on his images afterwards.
Allister had told us in advance that he is the kind of wedding photographer who prefers to stay in the background and keep a low profile, and this is exactly what he did. Apart from the staged group and family pictures we asked him to do, he was almost invisible for us. This attitude also transpires in the many images he captured in which people are clearly unaware they are being photographed – which in our view was exactly what made the images so much more real and lively.
Working with Allister was a pure pleasure. On a day where everybody is generally nervous, we especially appreciated his very professional yet relaxed and reassuringly calm attitude. And we were absolutely blown away with the results!
We can highly recommend his wedding photography services without hesitation and reservation.


This exercise is designed to strengthen the side abdominal muscles in addition to the chest, shoulders and triceps.
This is a simple glute stretch.
This stretch focuses on the glutes and inner thighs.
This exercise is great after any sport. It focuses on stretching the glutes and outer thigh muscles.


So i get to looking around at the forum to day. Not much has changed but i was looking and on the left side of the page is this Ads by Google UNDER THE CALENDER....... this was the link i found.. GUYS if it is not still there. I THINK THIS IS THE FUNNIEST THING I HAVE EVER SEEN!..


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Nest Hello Smart Video Doorbell Launches March 16 in Canada
One of the most anticipated smart doorbells, the Nest Hello, is launching in Canada on March 16th, as noted on BestBuy.ca.
The Nest Hello is currently available for pre-order at the price of $299.99 CAD from Nest and BestBuy.ca, which comes with a Google Home Mini (worth $79 CAD alone). The Nest website doesn't list the launch date, other than noting "March 2018", but reseller partners have now confirmed the launch date. The included Google Home Mini can announce who's at the door.
It starts at home. The conversations we have there shape who we are when we go out into the world. In case you missed it during the #Oscars? check out "Prom Night." pic.twitter.com/pD2sI4oRJr
— Nest (@nest) March 4, 2018
The latest smart doorbell entry from Nest brings HD video, night vision, 24/7 streaming, HDR support and a 160 degree field of view. It has a 4:3 ratio to show visitors head to toe, while also provides person, motion and sound alerts. A Nest Aware subscription will add face detection using AI.
Last month, it was reported Nest is being folded back into Google, joining the latter's hardware teams.
Click here to pre-order the Nest Hello on BestBuy.ca for $299.99.


text:
GP screening for h.pylori 'is cost effective'
Population screening for Helicobacter pylori reduces future healthcare costs for those who test negative as well as those who are found to carry the bacterium, UK research shows.
The researchers suggested a screening programme of 40-50 year olds carried out in general practice would be feasible in the UK.
A large screening study in West Yorkshire found that negative participants who were informed of their test results were less likely to consult for dyspepsia over the next two years compared with those kept in the dark.
The biggest reduction in GP time, prescriptions and endoscopy for dyspepsia occurred in those who although asymptomatic at the time of testing, had a history of dyspepsia.
The researchers from the Centre for Digestive Diseases at Leeds General Infirmary calculated for every nine people being told of a negative test, one would be prevented from seeking healthcare for dyspepsia in the future.
Study leader Dr Alex Ford said the results were further evidence of the cost-effectiveness of dyspepsia screening but also backed up current 'test and treat' guidance.
'We published a paper in 2005 looking at people who tested positive which showed you saved money over 10 years with population screening.
'But this is interesting because it's looking at the 73% who will test negative.'
He said countries such as the UK which have low prevalence of gastric cancer have shown reluctance to introduce a screening programme.
'But we show here there are benefits not related to gastric cancer.'
Co-author, Professor Paul Moayeddi, head of gastroen-terology at McMaster University, Ontario, Canada agreed that in the UK a serology-based screening programme of 40-50 year olds would be the best option.
He added: 'Test and treat is carried out in the UK more than most countries in the world but it is still sporadic.
'I would guess about 25% of GP test and treat regularly whilst the rest do it intermittently or not at all.'
As part of the screening study published in Alimentary Pharmacology and Therapeutics 1350 individuals who tested negative were told of their infection status and 1350 were given placebo triple therapy.
The study The study


Emerging Novel Therapeutic Agents in the Treatment of Patients with Gastroesophageal and Gastric Adenocarcinoma.
With further understanding of the biology of gastric and gastroesophageal adenocarcinomas, strides are being made to find effective treatments through novel trial designs. This article focuses on the ongoing trials of drugs targeting specific hallmarks of gastric and gastroesophageal cancers, including oncogene addiction proliferative pathways (fibroblast growth factor receptor 2 amplified tumors), stem cell inhibition, apoptotic induction through claudin inhibitors, and matrix metalloproteinase inhibition. In developing novel therapeutics in treatment of patients with gastroesophageal adenocarcinomas, parallel research efforts to refine target population and biomarkers are crucial, and targeting the tumor genomics and microenvironment may be key in improving overall survival.


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[Research] Research about pokemon and children's culture
November 01, 2004 / Nicolas
I stumbled across this research projects which I found appealing: POKÉMON: A Cross-Cultural Analysis of Children's Global Media Culture.
The Pokémon project examined the rise and fall of one of Japan's most profitable and popular exports. (...) In 1999, Professor Joseph Tobin of the University of Hawaii, an internationally renowned scholar in the field of Japanese/American educational and cultural studies, gathered a multi-national research team to investigate the Pokémon phenomenon.
The conference they held about it was called 'Pikachu's Global Adventure', it is available now as a book. The methodology they used is pretty interesting, especially the last point:
An overview of the Pokémon phenomenon, considering the production context (of the Nintendo Corporation), the characteristics of Pokémon texts, and debates about audiences. These findings were set in the context of broader debates about the relations between 'structure' and 'agency' in Cultural Studies.
An analysis of children's creative writing using Pokémon themes and characters. Four stories written by 8-9-year-olds were analysed in detail, in order to explore the creative nature of children's engagements with Pokémon, and the ways in which their writing functions as a form of identity construction.
Research with reception class children (aged 4-5), exploring the nature of children's play using Pokémon toys and artefacts. This study explored how play can give status to officially 'disapproved' forms of knowledge, and thereby empower children whose position in the classroom would otherwise be marginal.
A case study of one child learning to play the Pokémon computer game. The analysis considered the use of knowledge and skill in game playing; the social negotiations that surround it; the interaction between the game and other media forms; and the nature of 'interactivity' in games of this kind.
categories / Culture
[Prospective] Voicemail extinction?
Older November 01, 2004
[Prospective] Closer to Johnny Mnemonic Jones' than ever


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Cornell Provost Kent Fuchs named president of University of Florida
by Jeff Stein October 15, 2014 October 15, 2014
Ithaca, N.Y. — Cornell Provost Kent Fuchs will be leaving his position to become president of the University of Florida.
A statement from President David Skorton released Wednesday did not say when Fuchs would leave his current job. Skorton said a replacement would be announced by Oct. 31.
Skorton himself will be leaving the university presidency soon, meaning the university's top two positions will soon be held by new leaders.
Provost Kent Fuchs
Skorton's statement said:
"Kent's first years as Cornell provost coincided with the start of the economic recession, one of the most challenging times in our history. His leadership and insights helped us to make the necessary, and often difficult decisions to reduce our expenditures wisely. Thanks in large part to Kent's clear vision for the future, the University found creative ways to hire and retain diverse, outstanding faculty and maintain its strong academic profile. The University's strategic plan, Reimagining Cornell, and our new budget model are also important components of his legacy.
Perhaps Kent's greatest legacy as provost will be the Cornell Tech campus on Roosevelt Island. More than any other individual, Kent's foresight and determination resulted in our successful bid to establish Cornell Tech.
We will greatly miss his leadership, intellect and thoughtful, principled actions. Personally, I am excited for Kent and look forward to our continuing partnership as we each continue to contribute to the advancement of education and research at a national level.
Please join me in congratulating Kent for his 12-plus years of service to Cornell, for a job well done, and a new position well deserved.
We will be updating this story later.
Jeff Stein
Jeff Stein is the founder and former editor of the Ithaca Voice. More by Jeff Stein


Increasing attainment levels and reduction of early school leaving.
Career guidance should be based on the cooperation among several providers (locally, nationally, internationally) and on the integration of several resources (traditional ones, but, overall, innovative and digital ones, mostly already available on the web).
Improving the quality of career guidance at school.


Despite a cold blustery evening, and the game being live-streamed on the internet, a good crowd turned out to see Cornwall win the Tamar Cup for a seventh successive year.
It was not all plain sailing, Devon gave a good account of themselves and served notice that they will be tough opponents when the sides meet again in the Bill Beaumont Cup on May 12th, however as with the scones in pre-match buffet, the cream was very much on top!
Camborne's James Goldsworthy had to withdraw, so Jamie Hoskin (St. Ives) came into partner Jack Heazelton in the second row.
On the bench Dom Conner, Fraser Honey and Jack Simmons had to drop out, indeed Simmons only failed a late fitness test, I spoke to him before the game and he was very disappointed.
Rhodri McAtee came in as did two local favourites Matt Shepherd and lock Mark Vian.
Speaking after the game Cornwall head coach Graham Dawe was satisfied with his side's performance. "I was really pleased with the performance and endeavour shown, a few new lads came in and treated the shirt with a lot of respect, we tackled hard and unlocked their defence at times, so overall pleased.
"I was pleased with number of our new faces Ben Humber, Jack Hazelton, Lewis Wells and Jamie Hoskin all worked hard and showed what they are about.
Much of the first quarter saw Devon camped in the Cornwall half as they had the best of the wind. Cornwall put in some big tackles notably from Ben Humber and BJ Chapman, whilst skipper Jake Murphy got through a lot of work in defence as well.
Eventually Devon pressure told as they scored off a catch and drive with no.8 Martin Browne getting the unconverted try.
Good play from wing Kyle Speare, Murphy and replacement Taron Peacock helped set up Humber for his second try of the night again bettered by Mankee for a 14-5 half-time lead to the black and gold.
Both Rob Elloway and Matt Shepherd came on for the start of the second half and both were soon in thick of the action.
Devon still looked threatening with good runs from both Charlie Briant and Matt Crosscombe. Eventually they did score a second try through the forwards when prop George Snell crashed over, fly-half Cameron Setter popped over the extras.
Cornwall's fitness told in the final ten minutes when both centre Jon Dawe and Speare went over for unconverted tries to confirm the Cup staying this side of the Tamar for another year.
Cornwall: M Vague (Penryn), W Morton (Saltash), J Murphy (Barnstaple, Capt), J Dawe (Launceston), K Speare (Barnstaple), R Kevern (Redruth), D Mankee (Camborne); A Zacharovas (Camborne), M Ballard (Wadebridge Camels), J Drew (Camborne), J Heazelton (Truro), J Hoskin (St. Ives), BJ Chapman (Newton Abbot), B Humber (Wadebridge Camels), G Randlesome (Penryn).
Replacements: R Elloway (St. Ives), Z Cinnamond (Launceston), M. Vian (St. Austell), D Cook (Camborne) L Duke (Launceston), L Wells (Saltash), T Peacock (Camborne), J Champion (Camborne), R McAtee (Camborne), D Pearce (Launceston), M Shepherd (Plymouth Albion).
Devon: C Briant (Ivybridge), M Crosscombe (Plymouth Albion), R Palmer (Okehampton), M Grieveson (Ivybridge), K Browne (Newton Abbot), C Setter (Plymouth Albion), J Nash (Brixham); G Snell (Bideford), A Crouch (Barnstaple), W Vermingle (Exmouth), T Coates (Plymstock AO), G Wilson (Ivybridge), D Abrams (Okehampton), T Gratton (Okehampton), M Browne (Okehampton).
TASC Paul Bawden Man-of-the-Match: BJ Chapman, a fine performance from BJ who put in a lot of big hits on the opposition worked hard in rucks and mauls.


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Aktuell /
Christie's Rejects Oxford Scholar's Claim that $450M 'Salvator Mundi' Painted by Leonardo's Assistant
The auction house insists that there is a broad scholarly consensus that the record-breaking artwork be attributed to Leonardo
Leonardo da Vinci, Salvator Mundi (detail), c.1500, oil on walnut, 66 x 45 cm. Courtesy: Christie's, London / New York
Auction house Christie's has refuted an Oxford art historian's claim that the Salvator Mundi was largely painted by Leonardo da Vinci's assistant. Christie's said that there was a 'broad consensus' among academic opinion that the Salvator Mundi be attributed to Leonardo. The painting, which depicts Jesus carrying a crystal orb, sold for a record-breaking USD$450 million at Christie's, New York, last year.
Matthew Landrus, a research fellow at Wolfson College, Oxford, and a Leonardo scholar, has disputed the auction house's claim that the Salvator Mundi is 'one of fewer than 20 known paintings by Leonardo'. Instead, Landrus says that it was largely the work of Leonardo's talented assistant Bernardino Luini. Elements in the drapery and modelling of the face, Landrus said, bore significant similarities with Luini's own work Christ among the Doctors (1515–30).
A Christie's spokesperson rejected the claims, telling the Antiques Trade Gazette: 'The attribution to Leonardo was established almost 10 years prior to sale by a panel of a dozen scholars, and was reconfirmed at the time of the auction in 2017.' Meanwhile another Oxford academic and Leonardo expert Martin Kemp has said that he will reveal 'a conclusive body of evidence that the Salvator Mundi is a masterpiece by Leonardo,' in a book to be published next year.
How Powerful is Saudi Arabia's Soft Power Push?
Alongside the painting's attribution disputes, the identity of the Salvator Mundi's buyer has fuelled significant speculation. An initial Wall Street Journal report pointed to Saudi Prince Bader bin Abdullah bin Farhan Al Saud as the buyer, working as a proxy on behalf of Crown Prince Mohammed bin Salman. Saudi authorities said that the prince was actually buying it on behalf of the UAE's Louvre Abu Dhabi museum, where it will go on show later this year. Wilder theories have suggested that the painting's record-breaking sum was the result of an accidental bidding war between Saudi and UAE authorities, each thinking the other was rival Qatar.
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More Aktuell


A member who is in possession of both buy and sell orders for different beneficial owners for the same product and expiration month, and, for a put or call option, the same strike price, may execute such orders for and directly between such beneficial owners provided that in pit trading, a member executing such orders shall first bid and offer by open outcry three times at the same price, stating the number of contracts, and, thereafter, if neither the bid nor the offer is accepted, the orders may be matched in the presence, and with the approval, of a designated Exchange official.
Pursuant to an offer of settlement that SASCO Energy Partners, LLC ("SASCO") presented at a hearing on June 24, 2013, in which SASCO neither admitted nor denied the rule violations upon which the penalty is based, a Panel of the NYMEX Business Conduct Committee ("Panel") found that SASCO voluntarily submitted to the jurisdiction of the Panel for purposes of settling this matter and that on November 1, 2011, a trader employed by SASCO possessed opposite orders for different beneficial owners and simultaneously placed those buy and sell orders totaling 2,984 contracts with entry time differentials of less than five seconds for the purpose of rebalancing funds between these accounts over which he had discretionary trading authority. SASCO failed to diligently supervise its trader in a manner sufficient to ensure that he was familiar with Exchange rules such as through appropriate compliance training.
The Panel found that as a result of the foregoing, SASCO violated Exchange Rules 432.W. ("General Offenses - Supervision") and 533 ("Simultaneous Buy and Sell Orders for Different Beneficial Owners").
In accordance with the settlement offer, the Panel ordered SASCO to pay a fine to the Exchange in the amount of $30,000.


日本語を磨こう! Let's polish our Japanese!
READ real Japanese Today! By choosing short stories, the intimidation factor is greatly reduced. Not only that, but we divide the story up into tiny, easy-to-swallow segments with complete explanations to give you confidence as you read real Japanese page by page.
Perfect for upper beginner level students of Japanese.
BONUS! Get FREE MP3s of the story read by a native Japanese voice actress, one read at normal speed and one read slowly. Listen while reading. The link to the MP3s is found on the last page.
EXTRA BONUS! Included with the MP3s, are PDFs of all the vocabulary and grammar points. Feel free to print these out to use while reading.
Now with Furigana! All our readers now have furigana in both the paperback and Kindle versions. Furigana is the small hiragana over the kanji--most devices support this new feature.
Have you studied for a year or two but just don't feel like you are progressing? This book is for you too. We suggest reading the Japanese only section first (includes furigana) and then go through the line-by-line running gloss section to cement understanding and learn vocabulary.
* All Japanese have furigana (printed version and Kindle version on supported devices (most new devices)) and romaji for those starting out.
* Three complete Japanese short stories. Each story is presented in three unique ways.
* Two stories are about Hikoichi and the third is about a girl and a mask.
* GLOSS: Read the story with a running gloss—understand completely. Every sentence is broken down word-for-word and with English explanation of the grammar.
* JAPANESE ONLY: The full story in Japanese only (without the running gloss) is also provided so you can practice reading without interruption.
* ENGLISH SUMMARY: Finally, we have included a simple and mostly literal English translation for you to check your understanding (Don't cheat! Work through the Japanese first!).
* Short stories makes reading full Japanese texts possible.
* Download the FREE MP3s to listen while you study.
You may know our first Japanese Reader Collection Volume has several Hikoichi stories. By far, those have been the most popular among students. Hikoichi is, after all, an interesting character. Smart, sassy, creative in his laziness…In short, his adventures are entertaining. Plus, not many non-Japanese are as familiar with Hikoichi as they are Momotaro or the Moon Princess. So, be one of the few to dig in, enjoy, and learn more about Hikoichi!
Reminder: The digital version of the book is in NO shipping charge since it is in eBook format. The Paperback format only will have its shipping charge.
Please note: For Instant Download, you will receive a zip file which must be opened with a PC or Mac. Later, you can send the files to your phone or tablet.


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Pasifika is at the frontlines of climate change
"Many of us still have friends and family in the islands. The Pacific do not contribute significantly to greenhouse gas emissions, yet every Pacific Island nation is being impacted today."
On September 8, 350 is helping organise rallies in cities and towns around Australia as part of a global day of action – #RiseForClimate – to demand our local leaders commit to building a fossil free world that puts people and justice before profit. No more stalling, no more delays: it's time for a fast and fair transition to 100% renewable energy for all. Find an event near you at www.350.org/rise.
In Brisbane, the Pacific Island community will hold an action calling on the Brisbane City Council to divest from fossil fuels and move to #StopAdani. Lisa Viliamu Jameson from 350 Pacific Brisbane explains why it's so important that we #RiseForClimate. RSVP to the Brisbane event!
By Lisa Viliamu Jameson
Pacific Island nations are on the front lines of climate change.
Being part of the Pacific Island diaspora in Brisbane, we feel very passionate about standing up for our ancestral homelands. If we lose our ancestral homelands, we lose a part of our identity. I grew up going to Samoa and I feel very connected to my family and culture. These connections are very sacred to me and are things I want to protect for my future children.
It worries me that the way of life for Pacific Islanders is already being impacted by climate change. A lot of our people rely on hunting and gathering to feed themselves and their families. Climate change is impacting food and fresh water supplies. It impacts the seasons. We hear stories of the fishing patterns changing and the coral bleaching. People are noticing the changes today and that worries me, because how will it be in 100 years' time?
We want to see Australia move towards renewable energy and to stop burning fossil fuels. We know that fossil fuels contribute significantly to climate change and we know that Pasifika is at the frontlines of climate change.
Many of us still have friends and family in the islands. The Pacific do not contribute significantly to greenhouse gas emissions, yet every Pacific Island nation is being impacted today.
We want to see a transition to clean energy. We have the resources in Australia to transition but huge mining corporations are making profit at the expense of indigenous people including Pasifika people. I am rising for climate not just for Pasifika but also for Aboriginal and Torres Strait Islanders who are friends & family. We feel it is our duty to stand in solidarity with our brothers and sisters. We need climate justice and accountability.
Our Brisbane Pasifika community is rising for climate by using the very things that make us uniquely Pacific! We will use traditional dance, song and storytelling to rise for climate. Our action will have a Pasifika flavour by showcasing culture and ensuring that we involve all members of our community, both children and our elders. It will be a collaborative community event focusing on indigenous empowerment.
We will celebrate the resilience of our Pasifika people by displaying #PacificPawa (Pawa means Power in PNG Tok Pisin).
We'll be gathering at King George Square to send a message to local decisions makers that we need to keep fossil fuels in the ground and transition to 100% renewable energy.
We want to send a clear message to decision makers that the science is clear, we have the momentum, the technology for the energy transition is ready, and we demand bold action now. We cannot wait any longer.
With climate impacts escalating and our Pacific people being on the frontlines of those impacts, we simply don't have the luxury to wait to see what bureaucratic negotiations have to offer.
The Pacific Climate Warriors are calling for local institutions to commit to a fast and fair transition to 100% renewable energy for all and are working from the ground up to tell the world that if Pacific Communities at all levels can lead a transition to a Fossil Free future than the global world must follow suit.
You can Rise in solidarity with the Pacific Climate Warriors by signing the Pacific Pawa Petition.
By signing this petition you are adding your name to the growing number of Pacific people and people all over the world who are calling on their local institutions to show the world what true Climate Leadership is.
Sign the Pacific Pawa petition.
RISE FOR CLIMATE >


In Our Journey of more than 15 years, we have mastered ourselves in the field of Gypsum in Sakarni. We have a range of gypsum products like plaster of paris, ready-mix plaster, jointing compound and many more. We have added yet another vibrant colour to our product spectrum that is GYP board known as "SAKARNI-GIPSKARTON GYPSUM BOARD" . It was developed in collaboration with GIPSKARTON and abled technical assistance from Germany.


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In a Japanese Garden – film del 1912
 In a Japanese Garden – film del 1915 diretto da George Foster Platt


Education Cabinet Secretary Jacob Kaimenyi denied claims that he ordered the contentious fee increment in public universities.
By SIMON NDONGA, NAIROBI, Kenya, May 20 – Security has been heightened across Nairobi following plans by university students to stage protests over a controversial fee increment.
Nairobi Police Chief Benson Kibue told Capital FM News that anti-riot police officers were prepared to deal with the demonstrators in case they turned violent.
"In line with what has been happening recently with the terror threats, this is not the right time for people to be holding demonstrations. Unscrupulous people may be lurking around with the sole aim of disrupting the process. However, we wish to assure everyone that the proper security measures have been put in place," he stated.
The Students Organisation of Nairobi University (SONU) Chairman Babu Owino said they would be calling for the Higher Education Loans Board (HELB) to increase their bursary allocations by 50 percent to be able to cater for students' needs.
Owino said the protests would start from University Way through Uhuru Highway, Parliament Road to Jogoo House where they planned to present their petition to the Education Cabinet Secretary.
"The fee that is there at the moment compared to the HELB that is being disbursed to the students cannot sustain us so the idea of increasing fee is very irrelevant; we are planning a peaceful demonstration that will take us from Uhuru Highway, to Parliament, KICC and then finally to Jogoo House where we will end our demonstration," he stated.
The students from public universities vowed to stage demonstrations countrywide after negotiations between their unions and the government failed.
"Kaimenyi is fond of appearing in the media and stating that fees will be increased and then the following day he states otherwise so we do not know his stand. Let him issue a circular that is signed by him and let him give it to all the Vice Chancellors. But as at now, we take all his statements as speculation," he said.
Owino explained that they were in touch with their colleagues from other universities who would join the strike.
But as the students prepared to embark on the strike, Education Cabinet Secretary Jacob Kaimenyi denied claims that he ordered the contentious fee increment in public universities.
"The Government would like to allay the fears of stakeholders, and particularly university students about the purported increase," Kaimenyi noted.
In a statement, the Education Secretary stated that any increase must be initiated by University Councils, after a consultative process before it is endorsed by the Education Ministry.
According to Kaimenyi, the Universities Act, 2012 provides for setting up of the Universities Funding Board which would determining the maximum differentiated unit cost for the academic programmes offered in public universities.
"No such process has been started to this effect," he noted.


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Democratic White House hopeful Warren wins key progressive endorsement ahead of New York rally
NBN Breaking News
WASHINGTON/NEW YORK (Reuters) – Democratic presidential candidate Elizabeth Warren on Monday won the endorsement of the Working Families Party, a progressive group with growing political influence that previously backed U.S. Senator Bernie Sanders during his 2016 White House bid.
FILE PHOTO: Democratic 2020 U.S. presidential candidate Sen. Elizabeth Warren speaks to members of the media during a town hall at the Peterborough Town House in Peterborough, New Hampshire, U.S., July 8, 2019. REUTERS/Elizabeth Frantz/File Photo
The group's endorsement of Warren, a U.S. senator from Massachusetts, reflected its belief that "sitting on the sidelines" during the Democratic nominating contest is not the best way to beat Republican President Donald Trump in November 2020, said Maurice Mitchell, national director of the Working Families Party.
The organization's thousands of dues-paying members voted to endorse after interviewing five of the 20 Democratic candidates: Warren, Sanders, former U.S. housing chief Julián Castro and New York City Mayor Bill de Blasio. Their backing of Warren comes as opinion polls show her gaining ground against the contest's front-runner, former Vice President Joe Biden, a more moderate candidate.
Warren got nearly 61% of members' votes, while Sanders drew almost 36% support.
Mitchell said progressive voters face a "tough choice" this year but that "Elizabeth Warren is offering an agenda of real structural change."
Warren wrote on Twitter that she was "grateful" for the Working Families Party's endorsement. "Together, we're going to make the big, structural change we need so that government works for all of us – not just the wealthy and well-connected," she said.
The endorsement came ahead of Warren's campaign rally in New York City on Monday evening, an event expected to draw thousands as she delivers a speech on corruption in Washington.
Earlier on Monday, Warren proposed a major rewrite of U.S. laws governing lobbying that she said was aimed at restricting corporate influence and rooting out corruption. In the detailed plan, Warren proposed barring elected officials and senior government appointees from ever becoming lobbyists.
She would also ban U.S. firms from lobbying on behalf of foreign governments, expand the definition of lobbyists to include anyone paid to influence lawmakers, impose new taxes on excessive lobbying by large companies and restrict the ability of industry officials to "dominate" the regulatory process.
The Center for Responsive Politics said in January that companies and others spent $3.42 billion on lobbying in 2018, the highest amount in eight years.
Warren's plan takes aim at Trump, a real estate developer who as president regularly visits his own hotels, resorts and golf clubs. She would require presidents and vice presidents to place business assets in a blind trust to be sold and require other senior officials to divest assets that could present conflicts.
Trump maintains ownership of his businesses but has ceded day-to-day control to his sons. Last week, Trump, who has refused to release his personal tax returns, said that before November 2020, he would release an "extremely complete" financial report.
Warren noted that T-Mobile US Inc, which won Justice Department approval to merge with Sprint Corp in July, "sent its top executives to the Trump Hotel in DC right after the company announced a merger."
On Friday, a federal appeals court revived a lawsuit alleging that Trump violated the U.S. Constitution by profiting from foreign and domestic officials who patronized his properties. Trump denies the allegations.
Warren wants to ban lobbyists from all fundraising activities, including hosting events or serving as campaign bundlers, bar senior officials and members of Congress from trading individual stocks and pay congressional staff salaries "competitive" with the private sector. She would bar all federal employees from becoming corporate lobbyists for six years after leaving government.
She would also prohibit courts from using sealed settlements to conceal evidence in cases involving public health or safety and allow the public to sue federal agencies to enforce rules.
Warren cited General Motors Co's decision more than a decade ago to settle some cases involving deadly ignition switch defects on the condition the terms remain confidential.
Reporting by David Shepardson in Washington and Joseph Ax in New York City; additional reporting and writing by Amanda Becker in Washington; Editing by Colleen Jenkins, Peter Cooney and Dan Grebler
Tags: ahead, democratic, endorsement, hopeful, House, key, progressive, rally, Warren, white, wins, york
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