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Q: Iterative tree calculation in scheme I'm trying to implement a function defined as such:
f(n) = n if n < 4
f(n) = f(n - 1) + 2f(n - 2) + 3f(n - 3) + 4f(n - 4) if n >= 4

The iterative way to do this would be to start at the bottom until I hit n, so if n = 6:
f(4) = (3) + 2(2) + 3(1) + 4(0)     | 10
f(5) = f(4) + 2(3) + 3(2) + 4(1)    | 10  + 16 = 26
f(6) = f(5) + 2f(4) + 3(3) + 4(2)   | 26 + 2(10) + 17 = 63

Implementation attempt:
; m1...m4 | The results of the previous calculations (eg. f(n-1), f(n-2), etc.)
; result  | The result thus far
; counter | The current iteration of the loop--starts at 4 and ends at n
(define (fourf-iter n)
  (cond [(< n 4) n]
        [else
         (define (helper m1 m2 m3 m4 result counter)
           (cond [(= counter n) result]
                 [(helper result m1 m2 m3 (+ result m1 (* 2 m2) (* 3 m3) (* 4 m4)) (+ counter 1))]))
         (helper 3 2 1 0 10 4)]))

Several problems:

*

*The returned result is one iteration less than what it's supposed to be, because the actual calculations don't take place until the recursive call

*Instead of using the defined algorithm to calculate f(4), I'm just putting it right in there that f(4) = 10

*Ideally I want to start result at 0 and counter at 3 so that the calculations are applied to m1 through m4 (and so that f(4) will actually be calculated out instead of being preset), but then 0 gets used for m1 in the next iteration when it should be the result of f(4) instead (10)

tl;dr either the result calculation is delayed, or the result itself is delayed. How can I write this properly?

A: I think the appropriately "Scheme-ish" way to write a function that's defined recursively like that is to use memoization. If a function f is memoized, then when you call f(4) first it looks up 4 in a key-value table and if it finds it, returns the stored value. Otherwise, it simply calculates normally and then stores whatever it calculates in the table. Therefore, f will never evaluate the same computation twice. This is similar to the pattern of making an array of size n and filling in values starting from 0, building up a solution for n. That method is called dynamic programming, and memoization and dynamic programming are really different ways of looking at the same optimization strategy - avoiding computing the same thing twice. Here's a simple Racket function memo that takes a function and returns a memoized version of it:
(define (memo f)
  (let ([table (make-hash)])
    (lambda args
      (hash-ref! table
                 args
                 (thunk (apply f args))))))

Now, we can write your function f recursively without having to worry about the performance problems of ever calculating the same result twice, thus going from an exponential time algorithm down to a linear one while keeping the implementation straightforward:
(define f
  (memo
    (lambda (n)
      (if (< n 4)
          n
          (+ (f (- n 1))
             (* 2 (f (- n 2)))
             (* 3 (f (- n 3)))
             (* 4 (f (- n 4))))))))

Note that as long as the function f exists, it will keep in memory a table containing the result of every time it's ever been called.

If you want a properly tail-recursive solution, your best approach is probably to use the named let construct. If you do (let name ([id val] ...) body ...) then calling (name val ...) anywhere in body ... will jump back to the beginning of the let with the new values val ... for the bindings. An example:
(define (display-n string n)
  (let loop ([i 0])
    (when (< i n)
        (display string)
        (loop (add1 i)))))

Using this makes a tail-recursive solution for your problem much less wordy than defining a helper function and calling it:
(define (f n)
  (if (< n 4)
      n
      (let loop ([a 3] [b 2] [c 1] [d 0] [i 4])
        (if (<= i n)
            (loop (fn+1 a b c d) a b c (add1 i))
            a))))

(define (fn+1 a b c d)
  (+ a (* 2 b) (* 3 c) (* 4 d)))

This version of the function keeps track of four values for f, then uses them to compute the next value and ditches the oldest value. This builds up a solution while only keeping four values in memory, and it doesn't keep a huge table stored between calls. The fn+1 helper function is for combining the four previous results of the function into the next result, it's just there for readability. This might be a function to use if you want to optimize for memory usage. Using the memoized version has two advantages however:

*

*The memoized version is much easier to understand, the recursive logic is preserved.

*The memoized version stores results between calls, so if you call f(10) and then f(4), the second call will only be a table lookup in constant time because calling f(10) stored all the results for calling f with n from 0 to 10.


Glabellar - The area before the eyebrows just before the nose.
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Hyperhydrosis means excessive sweating. Sweating is one of the most important ways in which the body loses heat, however, people with Hyperhydrosis produce sweat in amounts far greater than needed to control their temperature. Botox is recommended for the treatment of auxiliary Hyperhydrosis and when small doses are injected into the armpit area, Botox blocks the actions of the nerves that supply the echini glands, preventing the glands from hyperhydrosis - producing sweat. The effects of the treatment last for several months, typically four to seven, before a repeat treatment is necessary.
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Cosmetic are of different quality Should look which is the best one.
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text:
Q: How do I assign named-keys to values after a .split I have split a textstring into an array:
    var contact = text.split(',');

As the text string always contains words in the same order, I would like to assign each word with a key according to their order. What's the best way to do this?

A: This code snippet below should do the job
var keys = ["firstKey", "secondKey", "thirdKey"],
    tmp = text.split(","),
    contact = {};

for (var i = 0; i < tmp.length && i < keys.length; i += 1) {
    contact[ keys[i] ] = tmp[i];
}

console.log(contact);

redpajama_set_name: RedPajamaStackExchange


text:
Tigers falter as A's rally forces decisive Game 5
Oakland Athletics' Coco Crisp (4) begins to celebrate his walk-off RBI single against the Detroit Tigers in the ninth inning of their Game 4 of the American League Division Series at O.co Coliseum in Oakland, California, on Wednesday, October 10, 2012. The A's won 4-3.
By John Lowe, Detroit Free Press –
OAKLAND, Calif. — Five Detroit Tigers pitchers combined to get the ball to Jose Valverde for a ninth-inning save opportunity with a two-run lead Wednesday night.
By converting the save, Valverde would put the Tigers into the American League Championship Series for the second straight season.
It didn't happen. The Oakland A's amazing season wouldn't end.
Before Valverde got an out, Oakland tied the game on Josh Reddick's single, Josh Donaldson's double off the wall and Seth Smith's line-drive, tying, two-run double.
Two outs later, Coco Crisp singled in Smith for a 4-3 win, and now there will be a decisive Game 5 in this division series Thursday night with Justin Verlander pitching against Oakland right-hander Jarrod Parker.
The Tigers have to hope this is a replay in reverse of the '72 ALCS, when they overcame a two-run deficit on their final at-bat at Tiger Stadium to beat Oakland in Game 4 and force Game 5 — which the visiting A's won.
"This is baseball. This is why this is the greatest game of all," manager Jim Leyland said. "You get tested all the time in this game. This is a good test. I thought we played our hearts out."
Valverde was preceded by Max Scherzer (5 1/3 innings), Octavio Dotel (one out), Phil Coke (one out), Al Alburquerque (seventh inning) and Joaquin Benoit (eighth inning). The only run they allowed was unearned, off Scherzer in the sixth.
Benoit, who has been struggling, allowed a hit and walk with two outs in the eighth. Up came lefty-swinging Brandon Moss, who almost hit a tying homer off Benoit in Game 1. Now Moss represented the potential go-ahead run. Benoit struck him out swinging on an 0-2 pitch that dived low and away.
Leading 2-1 into the eighth, the Tigers added a huge run. With one out, rookie Avisail Garcia pinch-hit for Quintin Berry against left-hander Sean Doolittle. On 0-2, Garcia spanked a single through the hole into right and Omar Infante scored easily from second. That meant Oakland could no longer play for one run to tie and that the Tigers didn't need to guard the lines against an extra-base hit.
For the second time in the game, the Tigers had scored a) with the help of a sacrifice and b) with an RBI on an 0-2 pitch.
Scherzer took a 2-0 lead into the sixth on Austin Jackson's RBI single in the third and Prince Fielder's leadoff homer in the fourth.
Coco Crisp began the sixth with a smash off Fielder's glove for a two-base error. Crisp went to third on a wild pitch. Stephen Drew drilled a 3-2 pitch up the right-field gap, by far the hardest-hit ball off Scherzer yet. Crisp came home to make it 2-1, and the A's were going to have the potential tying run at second with none out — except that Drew for some reason tried to make it a triple and Infante, the relay man, threw him out.
Scherzer left for Dotel. The veteran right-hander fanned home-run threat Yoenis Cespedes and walked Moss. The lefty Coke came in for left-handed slugger Reddick, who sent a 1-0 pitch on a high arc to right-center. Jackson caught it on the front edge of the track.
Alburquerque took over for the seventh with the 2-1 lead. Many boos greeted him because he kissed the ball on the key comebacker he got from Cespedes in Game 2. The right-hander quieted the throng with a 1-2-3 inning.
It was another night of every-pitch-matters baseball on the East Bay.
Scherzer got four of his first six outs on strikeouts. The Tigers gave him a lead when Alex Avila pulled a double into right to open the third, went to third on Infante's sacrifice and scored when Jackson (with the infield in) lined a single well into left.
Verlander bounded out of the dugout onto the field to cheer the run. It was only the Tigers' second of the series that scored on a hit. The first was on Avila's homer in Game 1.
Fielder led off the fourth by launching right-hander A.J. Griffin's 0-2 pitch far over the rightfield wall.
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redpajama_set_name: RedPajamaCommonCrawl


Bottom of the table Staines Town were gifted a two goal lead at Holloways Park as a pair of uncharacteristic mistakes from Ravan Constable saw The Rams up against it after only four minutes.
In the second minute, as Beaconsfield's rejigged back four were still introducing themselves to each other, the usually reliable stopper allowed a routine low strike from left back Mack Miskin to go straight through him. Moments later the visitors' second attack finished with the other full back, Finn Tapp, wrong-footing Constable, who could not get down quickly enough to prevent the ball beating him inside his near post.
The home side were understandably shell-shocked but with prompting from skipper Wes Daly they began to settle to the task and get a foothold in the game which had shown signs of getting away from them almost before it had started.
That said, it was the visitors who had the next serious effort on goal, comfortably saved by Constable. Almost immediately at the other end, an exchange of passes between Marvin Morgan and Brendan Matthew released Matthew on the right of the area. His low shot was saved at the second attempt by Louis Dixon in the Swan's goal. Two minutes later the strike partnership combined again on the edge of the box and Matthew's slipped pass released Morgan who was thwarted by a brave plunging save from Dixon.
Beaconsfield were warming to their task going forward but some lackadaisical marking out of possession saw them remain vulnerable to the counter. Bill Montague and Andre Odetola were allowed too much time and space in the centre of the field to advance and drive the visitors forward but these breaks carried less threat as the half progressed and the home side settled down and began to dominate.
Matthew saw a header well saved and Bajram Pashaj and Joe Adoo-Peters were combining well on the left flank with Louis Stead and Sean Fraser on the right also prominent. The visitors were increasingly pinned back. The pressure finally told in the 26th minute. Luke Neville was given time to carry the ball forward to half way and played a diagonal ball which Morgan headed into the path of Bajram Pashaj, his low shot was saved by Dixon, the rebound fell to Matthew who tried to force the ball home but was closed down by a defender. He turned and laid the ball back to Morgan who stroked a right footed shot home from 10 yards. Game On!
Beaconsfield continued to press with the aerial presence of Jordan 'AJ' Ajanlekoko and Louis Stead causing problems for Dixon and his defenders but their good work was almost undone on a rare Staines break when Odetola found space on the right and delivered a teasing cross which evaded everyone and flashed past the far post. With their next possession, Montague and Luke Wright combined to release Thomas Gogo who left Adoo-Peters in his wake and Luke Neville on the seat of his shorts before sending in a low drive which fizzed inches wide of the post and into the side netting.
At the other end chances continued to come, Luke Neville met a Wes Daly free kick at the far post but could not steer his header on target. Bajram Pashaj, put through on the left, cut in from the corner of the box and fired in a low shot which Dixon did well to turn around the post at full stretch. From the resulting corner, Matthew headed just wide.
In the 36th minute, the home side were level, Adoo-Peters received the ball from Matthew and fed Wes Daly in midfield, 30 yards from goal. The skipper was adjudged to have been fouled by Thomas Gogo who grabbed an arm as Daly went past. On reflection a soft one but enough for the award in the view of Mr Sunny Gill.
Bajram Pashaj stepped up and bent the free kick over the wall and into the corner with Dixon grasping at thin air.
As half-time approached Staines showed they were not about to lie down and Finn Tapp was again on target but this time his stinging rising drive was tipped over by Constable.
Honours even at the break, 2-2.
The second half began as the first half had ended - the home side enjoyed the greater share of possession and pressed the visitors back but still looked vulnerable to the counter.
On 47 minutes The Rams should really have taken the lead, Brendan Matthew made space at the left corner of the box and curled in a looping shot which was well saved by Dixon onto the foot of his post. The keeper was helpless as the rebound fell to Louis Stead who could not get any purchase on his shot and scuffed it wide.
Two minutes later Matthew was pulled down 35 yards from goal. Wes Daly curled in a teasing free kick which was met by Morgan towering above the defence, his glancing header seemed destined for the bottom corner but was brilliantly saved by Dixon who plunged to his left to turn the ball around the post.
Chances were coming thick and fast Morgan was again unlucky when he beat his marker on the edge of the box and as a covering defender and Dixon converged the rangy striker fired in a shot which cannoned off the angle of post and bar.
You suspected that The Rams may pay the price for squandering these chances.
Staines rallied forcing a corner which caused panic in the home defence and some desperate defending with Stead and Daly making last-ditch blocks of goal-bound efforts. Steads block appeared to strike his arm but Mr Sunny Gil judged that the arm was in a natural position and there was no intent, turning away Staines protests for a spot kick.
Brendan Matthew could and should have added to the visitors broiling sense of injustice when he burst on to a Wes Daly through ball, drew Dixon and went round him before stroking his finish from the angle of the six-yard box onto the outside of the post and away to safety.
He made amends for his glaring miss in the 74th minute. Picked out on the edge of the box by Ajanlekoko, Matthew turned and made room to curl in a right foot shot, which glanced off the back of Gradi Milenge and gave Dixon no chance. They say when you are at the bottom you get no luck and whilst the goal was no more than The Rams deserved on the balance of the second half the manner of it was a tad harsh.
To their credit, urged on by Wright and Montague the visitors' heads did not drop and they dominated the final 10 minutes. On another day they would have equalised but for the heroics of Constable who made amends for his earlier mistakes with a triple save clawing out a close-range header from Milenge, turning away the rebound, a cross-shot from Charles-Valentine, before diverting Tapp's resulting effort over the bar off his outstretched right foot and ankle. When it's not your day!
Barring some handbags and silliness as Beaconsfield ran out the clock there was no further incident. Luke Wright can consider himself fortunate to escape punishment for a petulant kick out at Brendan Matthew. Mr Sunny Gil felt it harsh to yellow card Wright because Matthews reaction in the ref's view also would have warranted a yellow. This would have been fair enough but the midfielders frustrated kick was more like violent conduct, punishable by a straight red!
So The Rams get back to winning ways, in not exactly convincing fashion. They will need to improve against a strong Basingstoke side in their next outing.


June 20, 2018 [St. Petersburg, FL] - The Florida Holocaust Museum (The FHM) has partnered with the Tampa Bay History Center to offer its Speak Up, Speak Now!® program to students. This is the first time that The FHM is providing this program in Tampa.
"At the Tampa Bay History Center's History Adventure Camps, campers have the chance to learn about history in fun, hands-on ways, even if the histories are more difficult to understand. It is important for our campers to learn about tolerance and acceptance because these themes shape not only Tampa's history, but also world history and our daily lives. While it can be a heavy topic, The FHM has figured out a way to make these lessons understandable and relatable for our young history-lovers," said Hoffman.
The FHM's Speak Up, Speak Now!® began as a summer program teaching students about the importance of speaking up in the face of injustice, through the arts and group activities. In this program, students meet with Holocaust Survivors, law enforcement officers, and community activists. This program has recently expanded into the Pinellas, Hillsborough, and Sarasota County school systems and will expose even more students to the concepts of upstander behavior, the rights and responsibilities of living in a democracy, and speaking out against injustice.
For additional information about The FHM's Speak Up, Speak Now!® program, please visit: https://www.flholocaustmuseum.org/learn/speak-up-speak-now/.


Credit Agricole took a 708 mln euro hit for its stake in troubled BES. The French bank has had these shares since 1984, but failed to hold the Portuguese lender to account, says Breakingviews.
So Credit Agricole was accessed from bash this -- -- bring these calls predictably clumsy Dominic Eliot's eyes had to explain why I I guess this title. -- -- Similar exits. In peripheral Europe. The costliest. That's right I said we've had some and -- key agreed to buying can wage I think Indians Credit Agricole lost about two billion your -- How bank insert in Spain again. I was probably a loss the doubts 200 million euros that -- now today we've got them the essentially it's the full exit from. Daschle by who practical -- fourteen point 6%. And sending its second quarter results of its value in that -- -- zero complete right now. On the and that's partly because of this good bank -- -- explanation and the and the role of that. The M governments and in rescuing the primetime at 700 million Europe heads from what what does that number it cannot breaks down into you 500 million -- -- -- -- share in the losses that. -- -- -- tell -- recently for the second quarter which I think with three point six billion -- something about magnitude and also. This 200 million write down which I mean that's what the stake is -- doubt about 200 million. And now it's 78 -- zero and so that does the extra -- I'm just looking at the. The the the -- text peace -- credit Jack -- C we can any regret having been misled by the family. With which I was trying to create -- true partnership the next paragraph talks of Credit Agricole signs representatives on the board bash. That -- -- questions. Actually I mean you go find guys on the board and even if they're walls for holds which we it's still an option to declare whether that walls aware that. This is something that's some board members nearby recognize. But it's even say they -- of make sure there's a bit more due diligence done the world to see these warning signs in the rights issue prospectus for example some people knew that there was some. Some things going on the world perhaps a little fishy I'm so yes I'm me when concerning the argument that great to stewardship here. We've been a good idea for Credit Agricole -- -- representatives bash. Am Credit Agricole were returned to profit. Lost to two years of losses. Given this financial. What what's that -- Near retirement like the credit that because I think Garcia looks funny in -- below rosier picture is you know underlying -- Business looks pretty okay it's the capital ratio has improved again until it's 10% at this level best distinctions. Is required these days and Credit Agricole strategy of course is to pull outs of these countries and when pressure was forced opponents -- but it it did want to get towel them anyway. And give new strategy is from some Italy that seems a lot more sensible. It's whatsoever stretched its cut down in the -- -- -- alienation -- -- -- 5% today. -- -- -- -- France in the retail bank it was on a platform that having two different economies and in a terrible position but yet crowd called it okay. Don't not just to finish with a want to -- put words in my -- forcing it to gazans the breaking news crystal ball but. Given. Exits from. Stakes increased stakes in Spain passed takes him in Portugal now. Clumsy. Exits. And of the ocean looking at a particular case of mistaken approach for Europe that we -- isolating the same -- about. And has pretty much it. Obviously it's really has halted the actual strategy side and and that's something that they all. Probably gonna do much better because that focus that yes I mean these peripheral stakes. That perhaps wasn't the you know the management. Application that could have been. It's this is probably a fitting coda to not hold periphery of you know dissolves the story I -- very get Dominik many things that the US has atrocities and seventeen patriots team. Alex appropriate sources.


Arrival in Tugu train station or airport Yogyakarta, tour guide and driver will pick you up. Then driving to hotel, check in and resting.
Wake up at 04.00 am, start to do exercise for Borobudur sunrise program. Enjoy the beautiful panorama in sunrise time from Borobudur temple. This is the biggest Buddhist temple in Southeast of Asian and built in 8th century. On the way to Salatiga, will visit to another 2 smaller temples such as: Mendut and Pawon. Continued drive to Dieng Plateau as the highest plateau in Java Island. There can visit the eldest Hindu temple of Arjuna, which built in the 7th century. Visit Sikidang crater as unique crater where we can see it from very close distance with bubbling mud. Then visit Color lakes as volcanic lake with beautiful bright color and Mirror lake as normal lake as well. Continued to Salatiga, check in hotel and resting.
Breakfast and check out hotel, process for plantation tour and there can learn about famous spices which grow on the hill, such as: cacao, coffee, clove, cotton etc. Continue drive to Solo and will visit Triwindu antique market, Radya Pustaka Museum. Check in hotel and resting.
Breakfast and check out hotel, process to Mangkunegaran Palace as the heart of Javanese culture in Java Island. Continue driving to Prambanan temple, as the biggest Hindu temple in Indonesia, which built by King Balitung Mahasambu in the 9th century. There were 333 temples there built by Hindus kingdom in that period. Drive to Yogyakarta hotel, check in and resting.
Breakfast at hotel, process to do white water rafting in Elo river Magelang. This rafting is for fun rafting with the length distance 10 kilometres and will take about 1.5 hours. Continue visit Merapi volcano for Merapi Lava tour, visit: Sisahartaku museum, Alien stone and Bunker Merapi. Drive back to Yogyakarta hotel and resting.
Breakfast at hotel, take learn of Batik making in course. There you can find out and practice yourself of making batik and get the thing you make as your own souvenir. Continued to the south of Yogyakarta to visit Parangtritis beach. This is a beautiful beach what Yogyakarta has and as the main place of ceremonial event held. Drive back to Yogyakarta hotel and resting.
Breakfast at hotel, visit to Yogyakarta Sultan Palace as the main centre of Javanese culture. Continues to Water Castle as private place of Sultan and wife spending the fun time, relaxing or recreation as well. Then visit Batik and Silver home industries as main souvenir from Yogyakarta city, in both places can see of how to make it in processing area or workshop. Continue to Malioboro shopping center, there are plenty of cheap handy crafts sale here with bargain able. Back to hotel and free program.
Breakfast and check out hotel, drive back to Tugu train station or airport Yogyakarta for departure. Jogja Tour services finishes.


Want to help clear up the confusion about Lyme disease? See the slideshow below for up-to-date research on Borreliosis and check out the resources to your left for thorough, evidence-based answers to your questions and concerns about Lyme disease. Want an overview of Lyme? Scroll down!
Lyme disease is caused by the spread of bacterial infection involving the Borrelia burgdorferi sensu lato genus. Lyme disease pathology and symptoms of Lyme disease condition correspond to the progressive involvement of multiple organs and systems in the body. Evidence of bacterial infection has been found in the skin, heart, peripheral and central nervous systems, and the joints. In some cases the presence of bacteria in organs such as the heart has only been found after autopsy and may have played a role in the cause of a patient's death due to long-term damage going undetected. The symptoms of Lyme disease are largely due to the immune system's response to the spirochaetes' presence in a particular organ or tissue, in addition to disruption of the hypothalamic-pituitary adrenal axis, and alterations in cell proliferation and death in brain tissue.
Following a bite from an infected tick of the Ixodes genus the saliva of the tick is transmitted with accompanying spirochaetes into the skin during feeding. This saliva has components which disrupt the normal immune response to a bite and which afford protection to the infectious spirochaetes allowing them to establish themselves in the local area. These spirochaetes then multiply and begin to spread outwards in the skin resulting in the characteristic bull's eye rash, erythema migrans. The redness of this rash is due to the immune system's provocation to mount an inflammatory response to the invading organism. Unfortunately, even as this inflammation occurs the neutrophils which should accompany it fail to materialise. Neutrophils are the immune system components which would aid elimination of the bacteria from the skin; thus, the spirochaetes continue to survive and thrive.
The reason for this failure of the neutrophils to converge on the infected area is the use by the spirochaetes of the protein plasmin found in the tick saliva to effectively hide from the immune system. Despite B. burgdorferi s.l. antibody production the plasmin confounds the immune system's efforts which is further obstructed by the spirochaetes ability to reduce the expression of surface proteins that would be targeted by such antibodies. This avoidance of detection involves alterations in the VIsE surface protein which effectively inactivates certain immune system components such as complement. Additionally, the bacteria may take up a position in the body's extracellular matrix that makes it difficult to reach by the cells of the immune system.
Over the days and weeks after a bite from an infected tick, the spirochaetes slowly enter the bloodstream from where they can gain access to almost every tissue in the body through the circulation. Infection can then spread quickly through the system and cause symptoms at places far away from the initial tick bite. The erythema migrans rash may now arise in other locations on the body as well as the original location as the spirochaetes cause other localised inflammation. Once again, the body's normal response leading to the elimination of the spirochaetes through the action of neutrophils is inhibited by the pathogen's use of the protease plasmin from the ticks' saliva. The Borrelia bacteria are also adept at other tactics to avoid being targeted by the immune system and have been said to 'hide' from the immune system.
These tactics employed by the Lyme disease bacteria have potential ramifications for the development of autoimmune complications. Exposure to the spirochaetes creates a chronic inflammatory response which may begin to damage ordinary bodily tissues due to molecular mimicry employed by the bacteria to avoid detection. In their imitation of normal body cells the bacteria can confuse the immune system into attacking ordinary body tissues which goes some way to explaining the chronic symptoms of Lyme disease experienced by some patients even after eradication of the infection by antibiotics. Where the immune system has produced antibodies against its own cells it will continue to attack these cells even in the absence of the Borrelia bacteria, leading to persistent symptoms including joint pain. Effectively, Lyme disease may induce an autoimmune condition similar to rheumatoid arthritis which persists even after the causative agent, the Borrelia bacteria, is removed.
Borrelia burgdorferi s.l. infection creates multiple symptoms due to it multisytem effects. In a large number of those infected, the symptoms only go as far as an acute flu-like illness which is effectively fought by the body and which leads to no other persistent effects from the tick bite. Stage II, early disseminated Lyme disease, involves the cardiovascular system and/or the central nervous system, leading to myocarditis, meningoencephalitis, and polyradiculitis. The levels of inflammation during this stage are much higher in these tissues than anywhere else in the early acute stage and can lead to significant tissue damage if the infection continues unchecked. Progression into Stage III Lyme disease involves more bodily systems, including the joints, and exerts more serious effects such as dementia and transverse myelitis.
The spread of the Lyme disease bacteria into the central nervous system varies in incidence and speed between individuals but when it does happen the spirochaetes may fundamentally alter brain function. It appears that astrocytes in the brain are involved in the pathogenesis of Lyme disease as these are glial cells providing support for endothelial cells that constitute the blood-brain barrier that protects the brain from damage by closely guarding entrance to brain circulation. The astrocytes are also important in maintaining nutrient supply to brain tissue, and in the repair process, and scarring, following trauma to the spinal cord or brain itself. The Borrelia bacteria induce astrogliosis in the astrocytes, a process where the cells rapidly reproduce and then die (proliferation followed by apoptosis). The effectiveness of the blood-brain barrier, the supply of nutrients to neural tissue, and the balance of ions in the brain can all be compromised through such events.
The secretory activities of brain cells are also adversely affected which is thought to contribute to some of the psychological and cognitive manifestations of Lyme disease. The spirochaetes can induce astrocytes and microglia to produce toxic substances such as quinolinic acid and specific cytokines interleukin-6 and Tumor necrosis factor-alpha, which damage nerve cells and can lead to the symptoms of fatigue and malaise in Lyme disease patients along with cognitive deficits such as memory impairment and poor concentration. Alterations in neurotransmitter function are also implicated in the development of some Lyme disease symptoms such as stress, anxiety, and sleep disturbance. There is some evidence showing that Borrelia bacteria induce the chronic elevated secretion of stress hormones such as cortisol which then reduce the effects of neurotransmitters and cause neurohormone disruption. Glucocorticoids and catecholamines are those neruohormones thought to be involved in this process and, with stem cell research recently revealing the benefits of anti-depressants such as sertraline (Zoloft) to be due to their effects on glucocorticoids, it appears likely that dysregulation of these pathways is a key factor in some neurological symptoms of Lyme disease. Reduced levels of tryptophan, a serotonin-precursor, have also been observed in those with infectious diseases affecting the central nervous system, such as Lyme disease. Low levels of serotonin in the brain are connected to symptoms similar to those found in neuropsychiatric disorders that arise in patients with Lyme Borreliosis.
There are similarities between Lyme disease pathology and conditions such as Systemic Lupus erythematosus (SLE) and Lupus profundus which can complicate diagnosis of both conditions. Lyme disease may resemble mild cerebritis with lymphocytes and plasma cells in the leptomeninges as found in SLE, along with a similarity between lymphoplasmacytic panniculitis in Lyme disease and lupus profundis due to the interraction between plasma cells and blood vessels. The chronic inflammation that occurs in Lyme disease also leads to vascular thickening in many cases along with scleroderma-like collagen expansion, and this can create a similar type of degeneration in the synovia as found in the vessels of lupus spleens.
Cutaneous disorders are also a feature of chronic Lyme disease infection, with acrodermatitis chronic atrophicans (ACA) a major feature in elderly European populations where the disease is endemic. Sclerodermoid-like reactions, lichen sclerosis et atrophicus, eosinophilic fasciitis-like lesions of the extremities, and subcuticular fibrous nodules have all been associated with the presence of spirochaetes. The specific nature of these cutaneous conditions and their incidence appears to vary according to the species of infectious Borrelia bacteria, with ACA less common in North American Lyme disease patients.
Long-term chronic manifestations of Lyme disease are increasingly thought to be due to induced autoimmune conditions rather than acute pro-inflammatory action by the infection, although experimental support for this theory is lacking in most cases with the exception of a small group of patients with persistent arthritis symptoms following Lyme disease infection. These patients were found to have immune reactivity to outer surface protein A (OspA) of Borrelia burgdorferi, and the human leukocyte function-associated antigen-1 (hLFA-1) indicating a possible initiating bacterial antigen and a cross-reactive autoantigen which would explain the development of Lyme disease-related treatment-resistant arthritis. Research published in April 2011 has however found that the enzyme 5-lipoxygenase (5-LO), which catalyzes the conversion of arachidonic acid into the leukotrienes and was previously suspected of involvement in the development of arthritis is in fact not a causative agent and is unlikely to be a useful therapeutic target. Deficiency of the enzyme does however appear to lead to earlier manifestations of the condition and an inability to resolve the arthritis in the longer-term.
The variety of pro-inflammatory and immunomodulatory-immunosuppressive features of are still only beginning to be understood and have significant consequences for the success of any treatments. Whilst antibiotic treatment appears appropriate for acute and early stage Lyme disease, later manifestations may require immunosuppresive treatment to combat autoimmune-related Lyme disease pathology.


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Honorary Members (2019-2020)
You are here to perform ethical deeds. Your contribution to the society will help you attain the next level in your journey.
(Volunteering TGG Foundation activities under the guidance of the Executive Committee)
Christopher A. Semler
Chris holds an M.S. in the field of physiology, and is currently pursuing a PhD in the field of education psychology. His studies have instilled within Chris a desire to realize and share the naturally occurring wonder which arises on exposure to our genuine curiosities. Chris acknowledges that individual's differ in preference and interests, but feels strongly that the natural world is present, in some fashion, across all distinct curiosities. Thus ELP, TGG's Experiential Learning Program, has come to be. This course is designed to emphasize the role of nature as our guide, as part of a process of reuniting with the fundamental regard which has allowed life to thrive in our ever-evolving ecosystem.
Premkumar
Prem, a B.sc graduate from Calicut University is specialized in marketing and business management and is currently running a business of his own in wedding cards and screen printing materials sector in Calicut , kerala. He has been in business from past 20 years and have won the best business man of the year award from chamber of commerce consecutively. He has been the driving force behind Wayanad Print O Pack, a social enterprises start up supported by the TGG Foundation. As an active working committee member of the trust, he is responsible for establishing the packing and distribution center in Mysore & Providing Start up services for Social Enterprises & Handicraft Artisans.
Sonal Karamchandani
Sonal completed her studies in Singapore and went on to pursue her interest in holistic healing methods. She's a Reiki Master, Psychotherapist, The Journey Practitioner, NLP and Breakthrough Life Coach as well as conducts Interactive Hypnotherapy sessions offering numerous methods to heal from physical to emotional labels and conditions. Best known for her innate ability to intuitively identify the root cause of patterns that are keeping individuals blocked, she works with various foundations and charitable homes with underprivileged kids, sexually abused individuals and emotional traumas. In addition to her private practice, Sonal is also an essayist and blogger on soul healing, spirituality and healing psychology as well. As an active working committee member of the trust she is responsible for establishing a strong market for the ethical products produced by the farming community with the support and mentoring of TGG Foundation & Study & Submit a report on the Privileges/Facilities to be extended to working committee / Executive Committee / RIM Members.
Reetha Premkumar
Reetha, an Arts Graduate from Calicut university is currently running a partnership business of Digital Marketing in Calicut. She has assisted Navajyothi (Kerala), a self help group supported by TGG Foundation by helping them to start a Virgin Coconut Oil hand made unit and have also extended training to them. She is aware of the challenges faced by the financially poor families and have supported them through various charitable organisation she is associated with. As an active working committee member of the trust she is responsible for Digital Marketing of products that are produced by the SHGs registered with TGG Foundation, Setting up a social enterprise by involving other women members of the trust to provide a strong packing and distribution base to the Self Help Groups supported by TGG Foundation & Execute Aasha Ki Kiran Project to facilitate socially challenged.
Rob Marsh
Rob holds a BA Hons degree in Business Studies from Leeds Metropolitan university where he specialised in Brand Management and New Business Creation. His work experience is varied, but he spent the last 3 years working as a Senior Sales Consultant in one of the the UK's fastest growing and most profitable technology businesses. Rob has been the driving force behind Wayanad Clothing which is the TGG Foundation's flagship social enterprise. As a working committee member of trust he is responsible for creating livelihood opportunities for women in rural India, arranging sponsorship for machines and tools for the self help groups & Fund raising for the development of RIM Center in Mysore


South Unit Visitor Center is open daily, year-round.
Location: South Unit entrance adjacent to the town of Medora.
Extended hours June through September.
17-minute park film, "Refuge of the American Spirit"
Visitor Center, Maltese Cross Cabin, and restroom facilities are wheelchair accessible.
Painted Canyon Visitor Center is not your average interstate rest stop. Be alert for bison grazing in the area.
Open daily June through September.
Trailers at the park entrance serve as a temporary contact station for visitors to the North Unit. The original building had to be demolished due to structural failure. Planning for a new facility is underway. Park information, informal presentations, restrooms, and a gift shop are all available in this temporary facility.


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Best-Selling Luxury Cars 2005
By Dan Lienert
Cadillac is not unlike the Statue of Liberty.
It is not only a symbol but also a beacon of sorts; a light to the rest of the struggling U.S. automotive industry that with hard work and determination, prosperity (and market-share) is possible. General Motors' Cadillac subsidiary is proof that not only does Detroit still possess the ability to produce luxury cars but, more important, that a once-mighty brand can rebound.
Many upscale customers feel they must turn to foreign automakers for decent luxury cars. But Cadillac has returned from a slump in the 1980s and '90s to build some of the world's best upscale cars, including its new DTS sedan. Like the Statue of Liberty, Cadillac is a symbol for all that America can be.
The company has a towering, Lady Liberty-like presence in the following slide show as well, which is a list of 2005's best-selling luxury cars. Cadillac has three vehicles on the list--more than any other automaker. The only other companies with more than one vehicle on the list are Toyota Motor's Lexus and Honda Motor's Acura subsidiaries.
The slide show contains sales data for the first 11 months of 2005. Our definition of "luxury car" comes down to brand image. Acura is a luxury brand. Buick is not, nor is Mini. Some nonluxury brands produce the occasional luxury car, such as Volkswagen's ill-starred--yet excellent--Phaeton sedan, which is being retired from the unresponsive U.S. market. Nevertheless, none of those vehicles had high enough sales to merit inclusion on the list.
And despite the success of Cadillac, it is the only American automaker to make our cut, and its dominance is restricted to the number of nameplates and prices thereof. Four of the five best-selling cars are from Japan. One is from Germany.
But you can expect more and better American luxury cars down the road. Cadillac, for example, is planning a "super-luxury" car to go in its lineup above the STS sedan, which has a MSRP that ranges between $41,020 and $74,270, depending on which version one buys, and the $76,480 XLR convertible. This new vehicle, which would be either a sedan or coupe, would likely cost six figures and could have a V-12 engine. Expect to see it by the end of the decade.
And DaimlerChrysler's Chrysler subsidiary would like to manufacture an answer to Cadillac's cars. Supplier sources familiar with the automaker's plans tell us to expect a revival of Chrysler's Imperial nameplate at January's North American International Auto Show in Detroit. The Imperial prototype will resurrect the name Chrysler used on its top-of-the-line sedans, on-and-off, between 1926 and 1993 (for a time, Imperial was even a stand-alone brand, as Edsel was for Ford Motor ). Chrysler wants to build a new version of the Imperial sedan, and production could happen as early as model-year 2008.
The idea behind the new Imperial is to take Chrysler's 300 sedan, keep the philosophy and the proportions, change the sheet-metal and make the wheelbase longer. The Imperial would be a premium sedan above the 300 and would compete with Cadillacs top-end sedans. The 300C is an upscale sedan, but its base price is limited to $34,000 because the down-market, regular 300 sells for $10,000 less. The Imperial would have no such handicap.
But any future American luxury cars may have tough roads ahead of them. This has been a hard one for the auto business, and the luxury car sector has suffered too. As you will see in the slide show, more cars sales declined than rose. Cadillac may be making the best cars in its history, but--to state one example--the company's Escalade family has seen sales decline by 15% in 2005. And those luxury cars in our slide show that have seen increased sales this year have seen only modest increases. The largest percentage change was a 6% increase for Cadillac's $31,000, entry-level luxury sedan, the CTS.
As you will see in the following slide show, America is a long way away from ruling the luxury-car market. But Cadillac alone makes America a first-rate player in the luxury-car business. For a closer look, please follow the link below.
See our list of Best-Selling Luxury Cars 2005.
* To verify the data in the slide show, Forbes.com contacted every luxury automaker selling cars in the U.S. of whom we were aware. At press time, only Mercedes-Benz had not returned multiple e-mail messages seeking confirmation of sales figures.
Coming on Dec. 15 to Vehicles: The Worst Cars
Want to track news by this author or about this industry? Forbes Attache makes it easy. Click here.
Find the Luxury Car That's Right for You
Prices, Photos, Reviews and more on ForbesAutos.com.


These days the idea for camping or hiking is awesome. But it often gets in vain because of challenges for the campers not to have a sound sleep or nap after a long walk or feeling tired of reaching the place. Then the sleepy head finds little soft and light backpacking pillows for a rest.
No matter what if the body even lies on the grass. The travelers have much more skills through the years of travel experiments and mistakes on how to reduce the insignificant weights from the backpacks of them. Even, the experience will make you learn on how to find the redundant heaviness and merely the existing gear you cannot effort.
Time being, it has shaped more sophisticated with qualities. Thence the dream, fortunately, has ever increased for lighting the backpack with a revered skill. Now we are sharing you with 20 Ultralight little Backpacking Tips: on How to Shave your Pack Weight.
Sometimes we do have experience with Pack covers those unreasonable trash disposal bag it will ease you to keep all the gears inside. Nonetheless, trash disposal bags are more supportive for water-resistant, replaceable, as well as weigh a portion compare to a packed shelter.
The extra Straps considerably fashionable makes you feel good but it augments your burden of weights that is no longer wisely considered while on a trip. Likely, compression and sternum straps, manufactured logo, shoulder straps, extra hip belt etc. You can shave these sorts of things to hut a couple of spaces. Consider you pack the right gears, and then you do not even need to compress the straps.
A digital scale and compass are the valuable tools you know. The scale measures the items in weight in different situations while you trip would be a little help that is beyond saying. If things are getting wet and heavy, consider which items are more trivial and need no more use of it. Get knowledge particularly about the gear weights that help you board more tactically. Use a compass if deemed while the place you cannot tress.
Tie up your shelter to some adjacent rocks. If essential, try making a heap have it more stable. Rocks may also be utilized on hard surfaces where stakes are unable to infiltrate the ground.
Have you got any guy on your desired trip? If yes, you can merge your resources like not to bring two stoves and shelters if your travel partner has already taken this. What you can do before you go, just take some time to consider, share your taken items and distribute the gear weights of you lightly among the enthusiast members of the travel group you are with.
Carrying water makes you little loaded and heavy. Try to drink much water from the water source you have found as possible as you fill the thirst. Figure out how far the next looked-for sources are waiting for you and how much water that you really need to carry up to reach the other place yet.
Morning's dew may typically cover up the whole surface of your placed shelter. Afterward, increase a little wet if loaded up your bag inside. Always be certain to dry the tents, clothes, tarps and other gears out before stuffing. Moreover, you can hang on for dry out as you climb up or keep them in sunny places to pack up or even eat breakfast.
Perhaps no one considers taking the same thing twice, let alone tour with backpacking. No way, you no need to spare of any items double! After watching the double things while on tour I am pretty sure you will feel exhausted. Find the least number of clothes you are going to have.
While you are going to pack your clothes, find lightweight dresses in lieu of weighty clothing like cotton or just common denim for your comfort. Always be aware of the stuff weigh less, search for the ever-best quality for water-resistant for lessening the weight than traditional ones.
Always consider yourself about wearing the boots those are lighter in weight, dry quite faster than the normal one and are almost flexible.
Some water bottles contain chords with too many excessive parts. In comparison, water with a plastic bottle is lighter, cheaper, durable and especially great for liter size. Better find one of them from super shop to have along with you.
Dental floss is far better than taking the thread especially for stitching snatched clothes and consciously mending the gear you carry on. It can be easily utilized for dry your line or even tying items for the pack.
You can wrap the duct tape surrounding the water bottle to avert bulk and excess part of cardboard weights. Truly, Duct tape would be a great block to avoid blisters and help the gear repairs.
While on tour in different places, always try to carry an extremely light stove with alcohol fuel so that you cook anywhere.
Find a better and light travel toothbrush to lose your weight. You can make the full one into two pieces carefully and discharge the extended half.
Ask yourself whether you feel carrying the things you have taken, is there any lighter version available, can they be cut down, etc. Figure out a list to prepare if all gears are perfect to keep with you.
Avoid cell phones, iPods, weighty watches, GPS, and power banks, etc. These kinds of stuff feel you more exhausted while n a trip. Enjoy yourself in solitude. Find the situation and risk if you feel worried about security issue- say your dear ones earlier of time which places exactly you have planned for moving and expected time of your return.
A razor-blade would be a super light alternative to the knife in comparison that makes your backpack feel lighter.
Use Ultralight pillow To wane your woes during stay outside and to have a little nap bloat your suitable Ziplocs of your bag and wrap the extra clothes as well as stuff you need. The bag with Ziploc will give you some space, and the bag clothes may feel like some cushion.
Vaseline is quite necessary while traveling outside. Beside lip moisturizer, it is used for different purposes. Use some Vaseline on heels before your outings while morning, in order to reduce roughness○ Vaseline, is perfect enough for fuel that slow-burning and used as starting the fire. Vaseline can be supportive as a shield from infection outside.
Find a sleeping bag if it's light enough with more convenient and warmer without synthetic. Though it may somehow become wet for different situation and get almost barren, search the quality pack that should be a dry liner.
To get informed earlier about the weather condition of travel arena, you just require to have some gear with you to update yourself. It is essential to plan and be aware of ahead to go over the place. Prepare earlier for presuppositions of unbearable cold, scorching heat or trifling rainy weather those can halt carrying unnecessary gear.
Merely the batteries you require should be a great help for a headlamp of your own. Just ensure if they are new and fresh one. Most of them usually have 'lesser or red-light' those pull considerably less quantity of energy.
Avoid extra napping bag compression and even tent bags. As an alternative, pulp your bag for sleeping and tent the stuff down inside your bag. Meantime, they'll be feeling more comfortable and flexible.
What a great fun if you feel the shoes you wear seems almost nowhere on your feet. There you can avail a lot of light shoes those are even waterproof for the campaign. DIY shoes also have the options which are based on foam pads would be a great help the trip you cover as well.
While you travel, all you need is a sound sleep to get refreshed. Some gear you may use but Backpacking Pillows would be a little different. Perhaps it would be the best friend for your sound sleep. If you are unable to have a sound sleep, the drowsiness loses your attraction to browse the stunning of nature. And, finally, you will lose the hope for travel the next.
So before you start traveling find a better one for your sound sleep, make sure you have all sorts of necessary items and prepare yourself for watching wild animals. Guess how you feel then. Watching these find precautions and safety measures to travel. And take some light first-aid items and medicines to keep fit and take care of you.
With a little consciousness, you will consider yourself to be an expert traveler and willingly feel for the next adventurous travel. Bon, voyage!


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Main » 2016 » March » 6 » ISACA Acquires Global Capability Maturity Leader CMMI® Institute
ISACA Acquires Global Capability Maturity Leader CMMI® Institute
Acquisition expands opportunities to help organizations optimize their use of technology, increase stakeholder value and improve business performance
ROLLING MEADOWS, Ill. - Friday, March 4th 2016 [ME NewsWire]
(BUSINESS WIRE)-- ISACA, the professional association for IT governance, assurance and cybersecurity professionals, today announced that it has acquired CMMI® Institute, the global leader in the advancement of best practices in people, process and technology. By joining forces, the organizations will raise the level of enterprisewide performance for existing and prospective members and customers and reach more diverse markets.
ISACA provides knowledge, standards, networking, credentialing and career development to IT and cybersecurity professionals. Through its comprehensive guidance and services, ISACA defines the roles of information systems governance, security, risk and assurance professionals worldwide. CMMI Institute is the organization behind the Capability Maturity Model Integration (CMMI), the globally adopted capability improvement framework that guides organizations in high-performance operations. CMMI Institute provides the tools and support for organizations to benchmark their capabilities and build maturity by comparing their operations to best practices and identifying performance gaps.
"We are living in a time of dynamic change in our industry, and technology has more power than ever before to transform an organization. For nearly 50 years, ISACA has been committed to equipping the professions we serve with the resources they need to positively impact their enterprises," said ISACA CEO Matt Loeb, CGEIT, CAE. "Our acquisition of CMMI Institute will help us to broaden our focus on helping professionals and their organizations optimize their use of technology, increase value for stakeholders and improve business performance."
ISACA and CMMI Institute share a vision for advancing organizational performance that centers on driving excellence in the IT, information systems governance, data management governance, software, and systems engineering functions in organizations across a spectrum of industries.
"CMMI Institute is a natural fit for ISACA and we are very excited to unite with them to create new offerings for ISACA's member community," said Kirk Botula, CEO of CMMI Institute. "Together, we'll offer a stronger portfolio of business solutions and professional development to both of our global customer bases and accelerate the pace of capability improvement and high maturity operations in their organizations."
The number of organizations earning a CMMI maturity level rating in 2015 increased 28 percent in the US and 17 percent globally. Fueled by the demand among global business leaders to improve organizational capabilities and drive business results, CMMI Institute continues to grow year over year in the number of CMMI maturity level ratings earned by organizations. In 2015, more than 1,900 high-performing organizations earned a CMMI maturity level rating.
ISACA serves more than 140,000 members and certification holders working in the information systems governance, security, audit and assurance functions across all industries. This acquisition will expand ISACA's reach to the thousands of organizations to which CMMI Institute has awarded a maturity level rating to improve their organizational capabilities and achieve higher maturity in their operations through their software, systems engineering and process improvement functions.
"Information technology is the backbone of the world economy and an enabler of business innovation. ISACA helps professionals and their organizations in gaining value through the right technology models and by removing impeding factors like cyberthreats," said Christos Dimitriadis, Ph.D. CISA, CISM, CRISC, international president of ISACA. "Our acquisition of CMMI positions us well to accelerate our mission toward a more holistic approach, focusing even further on products and services engineering and operations."
ISACA and CMMI Institute will continue to operate separately, with CMMI Institute operating as a subsidiary of ISACA. Additional information is at www.isaca.org/cmmi-institute.
Kristen Kessinger, +1.847.660.5512
news@isaca.org


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Source: U.S. Army by Jason W Edwards.
Recovering from coronavirus: Three harrowing stories of surviving Covid-19 | BBC News
While many of the people who contract the coronavirus recover, there have been over 2,000 deaths in the UK. BBC has spoken with three people who had to be hospitalized after catching the virus. Karen Mannering was six months pregnant when she came down with a cough and fever that would not go away before it progressed into breathing difficulty. She tested positive for the virus and also had pneumonia in both her lungs. Another woman, Jessie Clark, was unable to receive actual testing for the virus due to shortages, but her doctor was positive she had it. She was only in the hospital for a few hours before being sent home, and they believe her boyfriend is an asymptomatic carrier. A third patient believed he contracted the virus from someone in his choir and spent several days in the hospital.
Source: https://www.bbc.com/news/health-52124554


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Kanye West poses with North and Saint West as he talks about what scares him the most as they grow up
by Asfa Shakeel
Kanye West poses alongside daughter North West and son Saint West as he talks about his concern for their self esteem in today's day and age.
Kanye poses alongside son Saint and daughter North. (Image source: Instagram/Harper's Bazaar)
In Harper's Bazaar's cover for their September issue, Kanye posed alongside his kids as part of a series of covers called The First Families of Music. The magazine describes the series as, "From Bruce Springsteen & Kanye West, to Christina Aguilera and Mariah Carey, the greats of rock, pop, and rap come together with their promising offspring and prove that the legacy lives on."
In the photo, Kanye stands in his own clothing, wearing his own wedding ring. He is holding his son Saint West in his arms with his daughter North perched on top of his shoulders. The caption of the picture reads, "I hope my children never lose their confidence to society."
Kanye has expressed his concerns about his kids growing up in the world he inhabits many times before. He shares three children with Kim Kardashian: 5 year old North West, 2 year old Saint and 6 month old Chicago.
Kanye has three kids with Kim Kardashian. (Image source: Instagram/Kim Kardashian)
In a song titled Violent Crimes from his most recent album, Ye, West rapped about being worried for North's safety as she grows up in a world of social media, online bullying and harassment. Lyrics from the song include, "Don't you grow up in a hurry / your mom'll be worried", "Don't do no yoga, don't do pilates / Just play piano and stick to karate / I pray your body's draped more like mine and not like your mommy's", and "I pray that you don't get it all at once / Curves under your dress, I know it's pervs all on the 'net / All in the comments, you wanna vomit / That's your baby, you love her to death."
The cover series also features other musical families, each accompanied by a one-liner that defines their perception of family in the context of their life. Here are all the quotes from The First Families of Music.
1. Kanye West:
"I hope my children never lose their confidence to society."
2. Bruce Springsteen:
"My best advice to my daughter: Keep your focus on what you really care about."
Image source: Instagram/Harper's Bazaar
3. Christina Aguilera:
"I love being mama bear and providing support, strength, and a safe haven to my babies and loved ones, knowing that, above all else, it's the most important job I have."
4. Lionel and Nicole Richie:
"I wish for my kids to discover who they are and explore their passions to the fullest."
Image source: Harper's Bazaar
5. Erykah Badu:
"I want my children to use their gifts in order to do service for others. That is, to make sure that their gifts are serving something bigger than themselves. And to do what I say."
6. Theodora Richards and Alexandra Richards:
"We are a traveling band of gypsies, this bunch. With everyone's crazy lives, it makes for great stories around the fireplace. Music, dancing, and laughter fill our home, and we make it so we're never apart for too long."
The issue of Harper's Bazaar will be available on August 21.
Got a story or tip? We'll pay for it! Email us at [email protected]
Harper's Bazaar Kanye West North West Saint West
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Thanks go to our counsellors; Margaret, Amanda, Fiona, Helen, Janet, Liz, Pat, Sue and Sarah and our supervisors; Margaret, Maura and Brian, who continue to give their time and skills. The level 3 course finished in January, and we welcome Christine, Emma, Felisa, Nigel and Tom, who are joining our team of counsellors. We also welcome Elizabeth and Jane, who trained elsewhere. This means that we will be able to reduce our waiting list over the next few weeks, which is good.
Administration: Rosalind has been kept busy in the office and is expecting a baby in June. She will be on maternity leave until September and we wish her well.
If you would like to stay & join us for a meal afterwards, then please let us know and we will send you the menu to order. The cost is £13.
Training courses: In April 2012, we plan to start an Advanced Counselling Course, level 4, (equivalent to a Diploma), which will run for 2 years. The purpose of this is to upgrade our training and professional standards to fulfil proposed governmental requirements for counselling. There are about 10 of our counsellors who are hoping to start the course. Margaret is planning to do the majority of teaching, which will be an enormous task and we are immensely grateful to her.
There is also an 8 hour Listening and Responding course which is suitable for both secular and church communities. It has proved to be of use to managers of organisations as well as church study groups. All fees and times are negotiable and fees are donated to Philippi for training and the maintenance of the service.
Unfortunately, it had to be cancelled due to lack of support, much to the distress of those who had signed up.
We are still hoping to fully fund the cost of the level 4 course and have had a few donations, for which we are extremely grateful. There is also the cost of the supervisor's course to be funded.
Unfortunately, because we are a faith-based organisation and not a high profile, mainstream charity, we do not seem to fit the criteria for many charitable works, despite the obvious need for counselling across the board, from professionals to the unemployed. Our clients come from churches and the community and we provide an accessible service, which complements existing provision. Therefore, the directors feel that the next stage is to approach the churches on the island to ask for their support. If you know of anyone who might be able to help in some way, then we would be delighted to hear from them. Small things all help. For example, please fill in the Community Matters form in Waitrose.
We continue to review our mailing list and offer you the opportunity to have the Newsletter emailed or still posted to you or your name taken off the list. Thank you if you have replied in the past. Please let us know your wishes, if they have changed. Contact details are below.


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Izard County
Melbourne, Arkansas
Home Crime Tips & Prevention Press Releases Most Wanted Sex Offenders Contact Us
Administration Chapel Criminal Investigation Detention & Dispatch Center Drug & Alcohol Interdiction K-9 Mobile Command Patrol Reserves Search & Rescue
300 Circle Drive
Melbourne, AR 72556
Pay Fines & Fees:
WEEKLY REPORT JULY 13-21
According to Sheriff Earnie Blackley, On July 13, Tommy Franks age 59, of Floral was arrested by Deputy Sean Tomlinson for possession of Drug Paraphernalia and FTA. Franks is incarcerated in the Izard County Detention Center without bond. Franks is scheduled to appear in Izard County Circuit and Court August 13.
On July 14, Edwin Teegarden age 47, of Dolph was arrested by Sgt. Steve Davidson for possession of controlled substance methamphetamine, Possession Drug Paraphernalia Methamphetamine and possession Drug Paraphernalia, possession of Controlled substance Marijuana. Teegarden is incarcerated in the Izard County Detention Center without bond. Teegarden is scheduled to appear in Izard County Circuit Court August 13.
On July 14, Travis Owens age 42, of Dolph was arrested by Deputy Sean Tomlinson for Possession of Controlled substance methamphetamine and possession of Controlled substance, possession of Drug paraphernalia Methamphetamine and Furnishing prohibited Articles, possession of Drug Paraphilia. Owens is incarcerated in the Izard County Detention Center in lieu of $20,000.00 bond. Owens is scheduled to appear in the Izard County Circuit Court August 13.
On July 15, Joshua Dockins age 33, of Oxford was arrested by Sgt. Mark Simino for absconding warrant on probation and parole and was transported to Izard County Detention Center. Dockins is incarcerated in the Izard County Detention Center without bond.
On July 15, Matt Lowry age27, of Batesville was arrested by Deputy Tyler Webb for DWI, No insurance, Driving left of center. Lowery was incarcerated in the Izard County Detention Center. Lowery posted a bond of $500.00. Lowry is scheduled to appeared in Izard County District Court July 25.
On July 15, Eric Stewart age 30, of Calico Rock was arrested by Deputy Toby Smith for Driving on suspended license, no insurance, Operation of vehicle without license plates. Stewart was incarcerated in the Izard County Detention Center an posted a $805.00 bond. Stewart is scheduled to appear in the Izard County District Court August 22.
On July 15, Dylan James age 25, of Batesville was arrested by Sgt. Mike Smith for Possession of Control Substance, Public Intox James was incarcerated in the Izard County Detention Center and posted a bond of $1470.00. James is scheduled to appear in Izard County District Court July 25.
On July 16, Alexis Hickman age 28, of Melbourne was arrested by Reserve Deputy Betty Vest for Domestic Battery. Hickman was incarcerated in the Izard County Detention Center and posted a cash bond of $ 1000.00. Hickman is scheduled to appear in the Izard County District Court July 25.
On July 19, Rogelio Reyes age 28, of Horseshoe Bend was arrested by Nick Taylor for Forgery. Reyes was incarcerated in the Izard County Detention Center and posted a cash bond of $500.00. Reyes is scheduled to appear in the Izard County District Court August 13.
On July 20, Johnny Cox age 42, of Melbourne was arrested by Deputy Brent Engles for Failure to Appear. Cox is incarcerated in the Izard County Detention Center without bond. Cox is scheduled to appear in the Izard County District Court July 25.
On July 20, Felicia Scott age 23, of Norfolk was arrested by Deputy Sean Tomlinson for Violation of interlock device, Possession of Controlled substance, Driving with suspended licenses, no Insurance. Scott was incarcerated in the Izard County Detention Center. Scott was issued an OR bond. Scott is scheduled to appear in Izard County District Court August 22.
On July 20, Bradley Scott age 56, of Mount Pleasant was arrested by Deputy Toby Smith for Driving on a suspended license. Scott was incarcerated in the Izard County Detention Center and posted a bond of $365.00. Scott is scheduled to appear in the Izard County District Court August 20.
On July 15, Joshua Dockins age 33, of Oxford was arrested by Sgt. Joshua Dockins for absconding warrant on probation and parole and was transported to Izard County Detention Center. Dockins is incarcerated in the Izard County Detention Center without bond.
Immediate release 07/22/2019
P.O.C. Sheriff Earnie Blackley For
Izard County Sheriff's Office | © 2017 - 2021
Izard County, Arkansas


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Missouri Man Deported Back to Mexico
Josue Noe Sandoval-Perez was deported from the U.S. 16 years ago for not having proper documentation. After returning and starting a life in the U.S., Sandoval-Perez was taken into Immigration custody and sent back to his native Mexico without getting a chance to even tell his family he was gone.
No Criminal History yet Deportation Inevitable
Sandoval-Perez returned to the U.S. to find work and support his wife and two children. For the past 16 years he has worked with no criminal record, paid taxes and served as the breadwinner for his family. After being picked up by immigration officials, he was sent to a detention facility for a number of days in which he was not allowed to contact his family.
After he was finally sent to a border town in Mexico, Sandoval-Perez was able to contact his family who did not even know he had left the country. Sandoval-Perez's case represents the many difficulties that face President Obama as he tries to work with the Homeland Secretary to create a more "humane" deportation policy. Many undocumented immigrants residing in the U.S. have strong ties to their community and family but because of previous immigration violations, this may limit their ability to receive leniency in the court system.
Prosecutorial Discretion not used as often as it could be
Immigration advocates would argue that Sandoval-Perez should have been considered for prosecutorial discretion, which is a concept based on looking at immigrant cases individually and analyzing whether or not DHS should deport the immigrants. In most cases where the family relies on the undocumented immigrant for financial support or they are the primary caretaker for children or a relative, courts tend to have more leeway.
In an interview in Mexico City, Sandoval-Perez pleaded with President Obama "…to end this discrimination, to change this… Family have to stop being separated." The Sandoval family say they came to the U.S. because they could not make a living and support themselves with the wages they earned in Mexico. Now, Sandoval-Perez's wife and kids are working with immigration advocates to help reunite their family.
If you have questions regarding applying for a visa or immigration laws, contact us at 314-961-8200 or visit our contact page.


Dome Coffee Shop , 293 Albany Hwy. This is a social get-together for Club and prospective members. Here we meet, talk, unwind, admire each others' bikes, swap tall stories Since it is a Ulysses event, it is aimed at the over 40's. If you are there for the first time, please introduce yourself. Guests welcome!
Dome Coffee Shop , 293 Albany Hwy. This is a social get-together for Club and prospective members. Here we meet, talk, unwind, admire each others' bikes, swap tall stories. Since it is a Ulysses event, it is aimed at the over 40's. If you are there for the first time, please introduce yourself. Guests welcome!


text:
Twin Peaks currently has 83 locations in 26 states.
Twin Peaks Restaurants announced Monday that it is teaming up with ApplePie Capital—an innovative capital markets partner exclusively focused on franchising—to allocate up to $30 million in debt capital to its franchisees and propel its franchise expansion to new and existing groups.
"It is of the utmost importance for us to ensure our franchisees can continue to develop," says Twin Peaks CEO Joe Hummel. "This partnership with ApplePie will allow us to help our franchisees grow through a lending program that aids their financial needs. This gives them more opportunity to consider new steps such as remodels or opening new locations. It can also be an option for refinancing when needed. This assistance will be key in driving expansion as we continue to capitalize on aggressive franchising opportunities while we move into new markets nationwide."
"We are excited to team up with Twin Peaks and their franchisees to make accessing capital easy," says Denise Thomas, CEO and Co-Founder of ApplePie. "We look forward to helping accelerate the brand's growth through our competitive financing program."


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Specifications snake reproduction justification + purchase price
Familiar with venomous and non venomous snakes
The most venomous snake in the world
Python breeding
The cost of marshmallow breeding
why can snake venom be so beneficial
Snake breeding problems
Various high-profit product lines
Buy the best types of Persian horn venom at a cheap price
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Snakes in The Philippines ( Venomous, Poisonous & Black )
deadliest snake Price List in November 2023
Deadly Snake Breeds Most Fastest Nonpoisonous
The purpose of implementing the snake breeding justification plan is to set up a snake breeding farm with a capacity of 80 snake rings per year. Meters of land and considered a mortgage person. Snake reproduction plan You might think that snakes are the scariest creatures in the world and should always be avoided; Yes, this is because some of them are highly toxic and can cause death if bitten. However, snakes have important benefits, especially in the field of medicine and pharmacy, which has made people more eager to work in this field. In the following, we tried to publish a post based on the rationale plan for snake breeding; Deliver useful information to specific animal breeders; We hope the information in this project will help pave the way for start-ups and step-ups. Snake identification These creatures are cold-blooded reptiles whose bodies are covered with scales. In fact, snakes are long, bodyless vertebrates that are usually cylindrical in shape capable of expanding and flexing. There are more than 3,000 known species of snakes in the world, distributed in most parts of the world except the cold polar regions. One of the most important characteristics of a snake is the production of venom or venom, which is divided into three categories based on the presence or absence of this characteristic: venomous snake, semi-venomous snake and non-venomous snake. The venomous teeth of venomous snakes are larger than other teeth and their bite is highly recognizable, while in non -venomous snakes the fangs are parallel to other teeth. The pupil of a venomous snake is elliptical (vertical) and round to non-venomous. The body skin of venomous snakes is mottled and colorful, while venomous snakes usually have simple skin. Venomous snakes have a triangular head with a short and thick tail, while non-venomous snakes have a round head and a tail that is narrow from the middle to the tip of the body. The movement of venomous snakes is straight, spiral and fast in non-venomous snakes. Semi-venomous snakes have all the characteristics of non-venomous snakes, except that their tails are slightly shorter and thicker. Snakes are also divided into categories based on the type of environment in which they live, including sea and land terrestrial snakes. Sea snakes live in the waters of seas and rivers and their lives depend on wet and humid environments; But land snakes are often found in plains, deserts, mountains, over bushes, in trees, rocks and in holes. Snakes are active in spring and summer, and go into hibernation in winter, especially in temperate regions, due to body cold. Another, one of the factors that helps keep snakes alive is the peeling process. It promotes the growth, health and vitality of snakes and prolongs the life of snakes. The average lifespan of snakes is estimated to be between 12 and 40 years. Reproduction in snakes, which occurs in the summer, often lays eggs.
A - Venomous snakes: The most important venomous snakes are:
parsley snake
Horned snake
Cobra rattlesnake snake
Types of snakeheads Alborzi, Taabi, Damavandi, Zanjani, Khuzestani, Caucasian, Urumia-e and Khoi with horns.
Types of sea snakes Cortis, Graclis, Cyanosynctosis, Ornatus, Spiralis.
Snakes, cockroaches and snake bites are also members of the venomous snake family. B- Non-venomous snakes: From this group of snakes, the following can be mentioned: Fire snake Diamond snake Leopard snake Full of snakes Dwarf snake Son of a serpent Arab snake blind Ordinary blind snake
The most venomous snake identified is the Australian-born terrestrial snake, which is one of the strongest venomous. The amount of venom in one bite is said to be able to kill 400 people. Snake reproduction training In the process of breeding and maintaining snakes, conditions similar to nature must be provided for them to continue to grow so that they can be venomous; Conditions such as humidity, temperature, ventilation, proper feed and other factors. Snakes are carnivorous organisms whose main food is rats. Rats bred for such purposes can be used to prepare it. It is said that eating a live rat can keep a snake full for up to 21 days. Snakes also need adequate clean water, where a water container should be placed. The environment in which snakes are kept should be clean and free of dirt.
Many people enjoy having snakes at home for a variety of reasons, including hobbies, interests, etc., and keep and care for them as pets. One of the most common snakes used for this purpose are the snakes that pose the least danger to housewives, Like all kinds of pythons. These snakes have a wide variety of animals, but not all of them are harmless, the most commonly used in the care of pets: Burmese, trees, nets, balls, and pythons. Carpet. Snake Breeding Center The venom extracted from snakes is used in the cryogenic and vaccine industries. Poison is one of the most expensive liquids in the world, so each gram is worth about 3 million tomans or the equivalent of tens of barrels of oil. For this reason, centers around the world have established centers for the breeding and maintenance of this profitable animal. European countries are the leaders in this industry in the world. They have established a snake breeding and processing center for recovered venom in the pharmaceutical industry to treat a wide range of diseases including hypertension, heart disease, prevention of bleeding during surgery, and treatment of various cancers. To use. For example, a snake farm operates alongside a pharmaceutical company in Hamburg, Germany, where more than 200 snakes are bred. Snake breeding in Iran Given the unique nature of snake venom in the pharmaceutical industry and also because of the penalties inflicting on the country, it seems that the development of this industry is one of the country's needs in the medical sector, although there are measures that produced in this field for several years. Our country has acquired a combination of snake venom that prevents the growth of cancer cells by up to 20%; However, due to the climatic situation of Iran and the presence of snakes such as cobras and parsley, there is the capacity and potential to make broader plans in this field to watch the development in the field of pharmacy and export. Its products elsewhere. of the world and busy with many people in this context. The Razi Institute is one of the centers in the country that breeds and maintains snakes by providing a natural breeding farm; It is said that when a snake is caught, the nature of its venom changes. In connection with this, they create the conditions in such a way that their breeding environment is completely natural. Also, one of the main programs of this institution is to use venom produced by farmed snakes to treat wildlife diseases and to produce vaccines against these diseases by creating an environment for reproduction and reproduction. Apart from snake venom, which is the main reason for its reproduction, snakeskin is also used in making all kinds of bags, shoes, etc.
Setting up a snake farm requires costs to be fixed in both fixed and variable parts. The most important costs invested in the fixed sector include the cost of construction of buildings, facilities and machinery, and current costs include raw materials, salaries and other items. People who want to enter the radar industry can meet part of their capital needs through facilities provided by banks to breeders if they have a breeding license. Concluding remarks As mentioned, snake venom is one of the most important liquids sold in the world market at very high prices. This industry is currently developing and unsaturated and has high potential for investment, focused on which can bring lucrative benefits such as currency exchange, economic development, job creation, etc for the country. Breeding snakes How to maintain, required capital, problems, licenses etc... The snake or in English pronunciation as Snake is a type of reptile that eats only meat and It has a very long body, long and without legs. The skin of a snake is made up of many scales and its body has very high flexibility. Snakes are made up of many different species, most of which are venomous and dangerous. Of course, it is better to mention that in most snake breeds, there is a skull on their head to prey on. Hunt bigger with the help of your jaws. Snake breeding has become one of the professions that attracts many people today Many of these people are not even aware of the problems and obstacles they face in this way. Invest in a snake breeding business without a plan. But the only purpose of breeding venomous snakes is to get their venom, it is to sell snake venom in the market. It has a very high price and that is why many people are tempted to tread this path.
First of all, it should be noted that there are different types of snakes that do not have venom and give their prey to They hunt live. But in some of these species, venomous snakes use their venom to kill their prey. They swallow it easier. Snake venom for medical use But the use of snake venom is very useful in medical applications, such as: treatment of various cancers, vaccines and serum Snake venom is an oil that is yellow or white in color and both clear and opaque. Snake venom contains 26 types of enzymes that help treat many diseases. Snake venom contains 90 to 92% protein after drying. The same protein found in snake venom quickly clots in the blood and is therefore broken down. Bleeding People injured for various reasons or bleeding during surgery are used. Snake types such as: cobra, parsley, snakes and horned snakes are among the most dangerous venomous snakes. And it is deadly to the whole world that the poison is so important and valuable. Each gram of snake venom costs 60 barrels of oil.
For the snake breeding business, it is best to know the relevant organization and the Department of Environmental Protection You need to have a lot of running to get a running license. Because the snake is one of the most dangerous animals and it cannot be licensed to anyone. Having a large farm caring for and breeding snakes, usually snakes when laying eggs of many babies It gave birth to many. Even with subsequent deliveries of each snake, the number of its offspring is higher and possible It can even reach 80 babies. Snake breeding farm in Iran For this reason, the field to be considered should be larger than the snakes in the open. And easier to grow. Having very safeguards to maintain the space of snakes is one of the most important things in snake breeding because Because snakes are creepy, they can easily find their way out and become dangerous to others. Also, for snake venom, the conditions must be completely sensitive and hygienic, and it must be well -equipped laboratory With the help of two or more technicians, poisoning with snakes can be done in a completely principled manner. After snake venom, it is time to dry the snake venom, which must be used according to special conditions and principles. Done from private devices. For more complete information, you can start this business by using the snake breeding justification plan.
Snake breeding is one of those professions that at first glance you are much tempted, and you think You can earn huge profits by selling snake venom. But in reality, this is not the case because each job has its own difficulty but in raising your snake You will also face many dangers and if security and protection issues when bitten by a snake Do not observe. You may see irreparable damage to yourself But at what price to earn high profits Are you one of those people who does everything to make money and take risks?! It's a good idea to do a little research about the way you invest. Getting information about the types of production lines will help you easily make decisions and choose the best production line for you. Introducing our Snake Venom Company Snake Venom Company is a very professional and large group in the field of providing profitable and profitable production lines. With the help of its free advice, it helps you achieve very high income in a short period of time. Our Company's profitable product lines are quite diverse, depending on your investment and interest. It helps you choose the most suitable and start your own business.
Because snake bites can be useful in the pharmaceutical industry, there are many companies that breed poisonous snakes.
Poisonous snakes are cultivated in many places because they produce good medicines
Mehrdad ghasemi
They use the venom of some snakes to prepare some medicines
implementing the snake breeding justification plan is to set up a snake and timely use of anti-snake venom reduces morbidity and mortality. Although in the last few years production
A snake is a dangerous creature that is crawling and its bite is deadly and poisonous
The poisonous snake has many benefits. The snake is a dangerous poisonous creature and its bite is fatal
A snake is a deadly animal with a poisonous bite, from which medicines are produced to treat various disease
Snake venom is used to produce vaccines and medicines
The most terrifying animal in my opinion is the snake
Mohammad Navid Arabi
Knowing that some people use snakes as pets is both scary and interesting
You can purchase this high-quality product using the numbers on the site
Poisonous snakes are very scary and we should avoid them and take care of our children
Afshin
The snakes that offer the least threat to housewives, such as all types of pythons, are among the most commonly utilized for this purpose.
Kimia davodi
Your product is a very special and strange product and it can definitely be used in different places
abbasi
I have been in love with snakes since I was a child, and I did not know that there was a company that breeds snakes, so I became interested in entering this snake breeding industry.
Hello good day.They use the venom of some snakes to prepare some medicines
Hello good day.I think Even with further snake deliveries, the quantity of its progeny is larger and still conceivable.
Hello, venom is extracted from the products produced on the export site. It is used in traditional medicine to get snake antidote
These snakes are very difficult to breed and should be done by skilled people
hosein soltani
Hello good morning
Venomous snakebite and its effects are a source of fear for people living in southern Nepal. As a result, people have developed a negative attitude towards snakes, which can lead to human-snake conflicts that result in killing of snakes. Attempting to kill snakes increases the risk of snakebite, and actual killing of snakes contributes to loss of biodiversity.
You wrote an interesting article about snakes, my general information went up, thank you
There are different types of snakes, the poisonous ones are much more than the harmless ones
Nafise
There is an expression which says: " people are afraid of unknown things"; it`s totally true. If people knew the value of snakes they would invest more.
Mason Edwards
I think Even with further snake deliveries, the quantity of its progeny is larger and still conceivable.
Snake venom has medicinal properties. And it is effective and healing for the treatment of many incurable diseases. It is also used as an antidote in serum production.
Reza javadi
Many people in all parts of the world are very afraid of snakes and they are really scary because some snakes have a very small part, but at the same time, with their poison, they can easily kill tens of people.
Snake venom is used to treat many diseases
anti-snake venom reduces morbidity andchildren getting bitten by copperheads and other venomous snakes has more than doubled in recent year mortality. Although in the last few years production of antivenom has
Breeding poisonous snakes is exhausting and very difficult, but it has a good result and several patients can be saved from disease problems.
implementing snake venom reduces morbidity and mortality. Although in the last few years production of anti-venom has
the snake breeding justification plan is to set up a snake breeding farm with a capacity of snake rings per year
promote biodiversity conservation and increase species of colubrid snakes, including the common human health in the local tissue to venom for a longer duration and increase the local
Zohreh Shirazi
Trader of Caviar


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