For a miner of any size just having a fantastic, high grade orebody in the ground is not enough to give real value to your company. A big deposit with grade will give the company a theoretical value but if it cannot be extracted efficiently and cost effectively in a form that is saleable on the market then it will remain a theoretical value. Australian company Mineral Technologies prides itself on a track record of converting projects from theoretical value to certain value. Providing life cycle services for mines from metallurgy to plant design and incorporating new technology to stay ahead of the competition, Mineral Technologies has proven itself as a best in class mining services and technology company operating on major projects across the globe.
The business itself was formed in the 1940s as a sand miner on the beaches of Eastern Australia. Over the last 75 years it has developed into the technology and mining expertise business that we see today. Mineral Technologies has now been owned by Australian infrastructure giant Downer for the last 17 years.
The engineering and mineral processing business has built up a wealth of experience and expertise in the physical separation of fine minerals, specifically using gravity, electrostatic and magnetic differences to separate specific minerals to a customers' brief. However, the company has far more in its armoury than mineral processing, as general manager Ken Roberts outlines.
"We have our own product range of equipment that we developed when we were a mining company, we used to build our own plants so we have an engineering capability, a laboratory capability and we still retain all those skills today as we go on developing solutions.
The work Mineral Technologies undertakes for its customers in its core capabilities; metallurgy, plant design, equipment selection, process auditing and bespoke solutions, is critical when it comes to progressing mining projects. Roberts describes the work as giving confidence and certainty to the project as an investment – markets can see how much it is worth, whether it can be extracted and what the final product will look like from the plant.
The company is extremely confident in the quality of the service it offers with performance guarantees backed up by financial and operational commitments. Roberts says the reason he is happy to offer performance guarantees is once the project has been worked through in the laboratory on production size equipment, the whole team is very confident of the outcomes for the process or plant on site.
A problem projects often face using multiple contractors is the loss of knowledge and application from the laboratory to the final process. Mineral Technologies provides a wide range of services across the project lifecycle which Roberts says has cost saving benefits but also the quality of the work is better.
"The real strength for us is that our metallurgists and engineers that work in the laboratory have started the process for the lifecycle and they are the people who end up on-site commissioning the plant and training the customers' people in how to operate the plant.
The Mineral Technologies model is fundamentally based on quality of delivery, cutting edge technology and pride in its work with customer service and loyalty front and centre in all areas.
Roberts prides the company on the idea that it is not just an engineering business but also a technology developer. Mineral Technologies is striving to develop the next solution for its customers to improve efficiencies, timing and cost savings. The work of improving the separation equipment or finding new ways to produce the equipment is completed by the research and development team.
The R&D team is tasked with finding new ways to apply manufacturing technology to keep the products price competitive. In addition, Mineral Technologies works with its customers to continually learn from each project, improve its service, and customise its offering for bespoke solutions. The latter has cemented Mineral Technologies' reputation in the industry.
"A new piece of equipment that we build can be customised to any particular customer's project. It could lead to a small percentage increase in performance in the plant but in the case of a mining venture that can be a significant increase in the actual profitability in that mine because they often work on such tight margins," outlines Roberts.
"If you have an orebody in the ground you really only get one chance to extract as much as you can so with the economics of that process in mind we use the technology we develop to maximise the potential return for the customer.
A global commodity downturn forced majors, juniors and mining services companies alike to revaluate their operations. The normally strong flow of capital had dried up thanks to lower profitability and therefore Mineral Technologies' role also changed.
Roberts explains that his focus became consolidating the relationships the company had with its long-term customers and looking at ways to reduce their costs to bring down the price per tonne of production. Instead of expanding or designing new plants Mineral Technologies was finding ways to optimise or diversify plants to get more out of the original process.
"The technology aspect comes to the fore and that allows us to take our people from the lab phase and put them on site to find ways to get more out of the plants for the customer," Roberts notes.
This strategy served the company well. As the market began to ride the upcycle the customers for whom Mineral Technologies saved significant money during the worst times are now remembering Mineral Technologies as new work comes along.
"We are seeing a lot of customers come back and want to do their next expansion with us because we stood by them and helped them survive the downturn and there is a lot of confidence to continue working with us.
Now that prices are returning to the market and there is capital available to bring new projects online Roberts has his hands busy with full order books and a growth strategy set for the next few years.
Firstly Mineral Technologies will continue to lead the market in mineral processing for its core business in mineral sands, iron and coal but it will diversify and expand into new areas such as gold and copper. The company announced a new non-exclusive global strategic alliance with Core Resources, a specialist hydro-metallurgical testing, process design and engineering firm based in Brisbane, to pursue new areas of business as well as move into end-to-end project solutions. Core Resources brings high end metallurgical smarts in the precious and base metals and industrial minerals commodities area combined with an expanding engineering plant design capability that is being built in Mineral Technologies.
"We are stepping out of the process plant and into both the mine and tailings management as part of the broader scope of our portfolio. We are moving from just the process plant to the whole of mine solution space and we already have several early stage projects in development.
Roberts and the team are not happy to sit back and admire the critical work they have completed on some of the world's biggest mining projects, there is a determination to remain at the cutting edge of new technology and use that desire to show customers how much added value there is in their orebody. Keep your eyes peeled for where Mineral Technologies goes next.


1.25Inch Oxygen III (O-III) are great for viewing diffuse and planetary nebulae.
The views of the Veil, Ring, Dumbbell, Crescent and Orion nebulae are dramatically improved.
It can crank up the contrast between them and the sky to reveal more of their wondrous detail.
It does so by transmitting close to 90% of the light corresponding to the two oxygen-III spectral lines at 496nm and 501nm while completely blocking virtually all other wavelengths.


» At least 2 pairs of thermal.
Disclaimer– Well medicines listed here are just my suggestion as it suits me and you shall always consul your doctor before taking any of these.
© Copyright 2007.Panna National Park. All rights Reserved.


text:
Blå örtlöpare (Lebia cyanocephala) är en skalbaggsart som först beskrevs av Carl von Linné 1758.  Blå örtlöpare ingår i släktet Lebia och familjen jordlöpare.

Beskrivning
Arten är bred för att vara en jordlöpare, med fyrkantiga täckvingar som har kraftigt blå eller blågrön metallglans. Mellankroppens halssköld är brandgul, även benen är brandgula fast med svarta knän. Arten är liten, med en kroppslängd på 5,5 till 8 mm.

Ekologi
Habitatet utgörs av torra marker på sand- eller grusjord samt alvarområden med riklig örtväxtlighet. De vuxna skalbaggarna förekommer under vår/försommar och höst på olika träd och buskar, samt växter från familjerna korgblommiga växter som (molkearter, tistlar, piggtistlar, röllika och hökfibblor) samt johannesörtsväxter (johannesörter). Skalbaggarna gömmer sig ofta tillsammans under olika föremål på marken, som stenar och liknande.

Larverna är parasiter på puppor av bladbaggar. De fullbildade skalbaggarna övervintrar som fullvuxna.

Utbredning
Utbredningsområdet omfattar södra Nordeuropa, Västeuropa österut till den autonoma regionen Xinjiang i nordvästra Kina. Arten finns också i Nordafrika.

I Sverige finns arten endast på Öland och Gotland. Den har gått kraftigt tillbaka, och är rödlistad som starkt hotad ("EN"). Tidigare fanns den, om än inte särskilt vanlig, från Skåne till Uppland och Västmanland (med undantag för sydsvenska höglandet), men den försvann därifrån kring 1970. Orsakerna till artens tillbakagång är habitatförlust till följd av igenväxning av de torra gräsmarker på vilka den lever. Konstgödsling kan också vara en möjlig anledning.

I Finland är arten numera klassificerad som nationellt utdöd ("RE"). Den fanns tidigare i sydväst, från Åland till Helsingforstrakten, norrut till landskapet Egentliga Tavastland. Senaste observationen gjordes 1954 i landskapet Egentliga Finland.

Bildgalleri

Källor

Externa länkar

Jordlöpare
Insekter i palearktiska regionen

redpajama_set_name: RedPajamaWikipedia


All of these packages contain all of the 90 nutrients recommended by Doc Wallach to provide your core or baseline nutritional needs. Everybody on the planet require these but less than 10% get them in their diet.
Click on the image for more information and Supplemental Facts.


text:
The 2020 Nissan GT-R Got Another Big Price Increase
Filed to: 2020 nissan gt-rFiled to: 2020 nissan gt-r
Image: Nissan
Each time a new model year of the Nissan GT-R comes around, it's a reminder that we're all a year older, and, like the GT-R, probably haven't grown much or significantly improved ourselves during that time. But the GT-R has one thing on all of us: the ability to keep going up in value, regardless of stagnancy.
Well, "value" isn't exactly the same as "MSRP," but you get the idea.
Nissan announced the price lineup for the ever-aging 2020 GT-R on Monday, and it's a whole lot different than last year, when Nissan simply bumped every trim up by $50 and went on about its life to mark the start of a new model year. (That's aside from the "Pure" base trim, which Nissan kept at the 2018 price of $99,990 in order to keep the entry-level GT-R out of the, gasp, six figures.)
This year, Nissan alluded to no $99,990 trim. The price lineup leaves the Pure out, and the bottom trim is the previously second-level Premium at $113,540. The Track Edition and Nismo trims also get price hikes, with the former going up by $17,000 and the latter by more than $35,000—the kind of numbers that would make a person think this was a new generation or something.
The newly $210,740 GT-R Nismo will have "GT3 race car turbochargers, carbon fiber roof and hood, revised suspension and carbon ceramic brakes," Nissan said, allowing it to "take performance to the next level." Price, too. The extra $17,000 on the Track Edition will get a person more power, since it's upgrading from the lower 565-horsepower GT-R engine to the 600-HP Nismo one.
Even the Premium trim, which is up by $3,000 over 2019, will get "revised twin turbochargers" on its 565-HP V6, a new interior accent color and a new design for its 20-inch wheels. Then, there's the 50th-anniversary edition for $122,040, which, contrary to popular belief, does not celebrate the 50th anniversary of the current-generation GT-R. That one's only been around since 2007.
But hey, good for Nissan. If any of us sniffling humans could convince others that we'd improved in the past year when we really hadn't done much, and that we were worth even more in spite of it, we'd milk it, too.
Long live the R35 GT-R, the world's most successful brick.
Nissan GT-R $50 More Expensive; Capitalism Wins, the People Lose; Car No Longer Worth It
The 2018 Nissan GT-R Is More Godzilla Than Ever: Ancient but Unstoppable
Nissan Let The Fans Down

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: linear-gradients not working in mobile web browsers I am writing a mobile web-app and I was wondering if someone could help me understand and fix these linear-gradients so that they work in both Safari-mobile and the Android-browser.
I believe I am using every vendor-prefix properly and I even provide a fallback background-color, but whenever I view the app on a mobile device, the element whose background the gradients are applied to is transparent. In other words, the background is transparent and the gradients are not showing up on mobile devices. Meaning, even the fall-back colour is not working either.
The even more weird thing is that they (the gradients) show up on the mobile simulators for android and iOS.
Can someone please help me fix these gradients so they work on both desktop and mobile devices and also teach me how to do working fallback background-colors and background-images ?
I would really appreciate any and all help!
Here is what I have so far:
background:#fff;
background:transparent -ms-linear-gradient(top, rgba(255,255,255,.65), rgba(255,255,255,.9));
background:transparent url(data:image/svg+xml;base64,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);
background:transparent -o-linear-gradient(90deg, rgba(255,255,255,.65) 0%, rgba(255,255,255,.9) 100%);
background:transparent -moz-linear-gradient(90deg, rgba(255,255,255,.65) 0%, rgba(255,255,255,.9) 100%);
background:transparent -webkit-gradient(linear, 0%, 0%, 0%, 100%, from(rgba(255,255,255,.65), to(rgba(255,255,255,.9));
background:transparent -webkit-linear-gradient(90deg, rgba(255,255,255,.65) 0%, rgba(255,255,255,.9) 100%);
background:transparent linear-gradient(90deg, rgba(255,255,255,.65) 0%, rgba(255,255,255,.9) 100%);

Thanks in Advance!

A: This should work for every browser (even mobile ones) just tested it:
#element {
    background: -moz-linear-gradient(black, transparent); /* FF 3.6+ */
    background: -ms-linear-gradient(black, transparent); /* IE10 */
    background: -webkit-gradient(linear, left top, left bottom, color-stop(0%, #000000), color-stop(100%, #ffffff)); /* Safari 4+, Chrome 2+ */
    background: -webkit-linear-gradient(black, transparent); /* Safari 5.1+, Chrome 10+ */
    background: -o-linear-gradient(black, transparent); /* Opera 11.10 */
    filter: progid:DXImageTransform.Microsoft.gradient(startColorstr='#000000', endColorstr=transparent); /* IE6 & IE7 */
    -ms-filter: "progid:DXImageTransform.Microsoft.gradient(startColorstr='#000000', endColorstr=transparent)"; /* IE8+ */
    background: linear-gradient(black, transparent); /* the standard */
    z-index: 1;
}

Check this two good web sites for css on browsers:

*

*Site 1

*Site 2
(I tested it on iOS 5.1.1 with this demo http://jsfiddle.net/luissanchezm86/4Kwb4/)
Hope it helps!

A: In mobile safari at least, you can't use the keyword transparent, you have to use rgba(255,255,255,0) instead. Proof: https://developer.apple.com/library/archive/documentation/InternetWeb/Conceptual/SafariVisualEffectsProgGuide/Gradients/Gradient.html
Search for transparent, you will see even in their official document, they use rgba for transparent color.

A: is the property transparent necessary?
see: http://www.colorzilla.com/gradient-editor/

A: I fixed this by using 'backgroundImage' instead of 'backgroundColor'

redpajama_set_name: RedPajamaStackExchange


Published 04/21/2019 12:29:25 am at 04/21/2019 12:29:25 am in Corner Tv Stands For Flat Screens.
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text:
Charles Umbs (April 29, 1876 – February 10, 1958) was an American gymnast. He competed in four events at the 1904 Summer Olympics.

References

Further reading

1876 births
1958 deaths
American male artistic gymnasts
Olympic gymnasts of the United States
Gymnasts at the 1904 Summer Olympics
Sportspeople from Wisconsin


text:
keep the blues alive
Main / Activities
Interviews / News
Events / Lives
My Mojo
Interview with storyteller/multi-instrumentalist David Olney - one of the most respected artists in the music today
Posted by Michael Limnios Blues Network on September 17, 2014 at 8:30pm
"Every culture in the world has some form of the blues. You can't master the blues but you have to confront it, you have to deal with it."
David Olney: Bright Lights Music City
Though multi-instrumentalist David Olney is a folk singer at heart, he incorporates wide-ranging inspirations from honky tonk to rock into his standard repertoire. Born in Rhode Island, Olney moved to Nashville during the early '70s and became a major player in the city's underground folk/country scene. He gained a contract with the folk label Philo several years later. Though his first half-dozen albums were recorded before the end of the decade, Olney's output during the '80s slowed considerably. He returned to Philo in 1995 with High, Wide and Lonesome, recorded with an impressive cast of roots rock all-stars -- Rick Danko, Garth Hudson, Sneaky Pete Kleinow, Rodney Crowell, and Brian Ahern, among others. Real Lies followed in 1997, including contributions from John Prine and Garth Hudson, while 1999 brought Through a Glass Darkly.
The prolific David Olney infuses his live performances with an intensity that converts many new listeners into die-hard fans. Mr. Olney's intelligent compositions radiate that same intensity and have earned a place as one of the most respected singer-songwriters in the world today. His songs have been recorded by Emmylou Harris, Linda Ronstadt, Lonnie Brooks, James King, Dale Ann Bradley, Ann Rabson, Tim O'Brien and others. He has released more than 20 albums over four decades, including six live recordings, and performs worldwide.
Showcasing yet another talent, David Olney has become synonymous with Classic Poetry as new fans have flocked to several of his stellar video recitations posted on YouTube, such as Samuel Taylor Coleridge's "Kubla Kahn"; Brownlng's "My Last Dutchess" and others. In late 2009, David began a weekly live broadcast - called "You Never Know" - sharing music, songwriting insight, good humor and wild stories. Master storyteller released in Jule 2014 his latest studio album, When the Deal Goes Down, on Deadbeet Records. This summer he did his debut as a Shakespearean actor in the annual Nashville Shakespeare in the Park Festival.
Interview by Michael Limnios Photos by Gregg Roth
How do you describe your sound and songbook? What characterize your music philosophy?
I play a folk based brand of rock. Early exposure to blues, especially Jimmy Reed, influenced me. When I first began playing in clubs I played folk songs with some blues thrown in. Bob Dylan changed the landscape and I took up writing songs. As a writer I try to be as clear as I can and at the same time be entertaining. I never write only for myself. I always imagine somebody listening.
What experiences in your life have triggered your ideas for songs most frequently?
I was raised in New England but moved to the South when I was in my teens. Being near the source of so much music that I loved was exciting for me. I felt I was suddenly close to songs that had seemed so distant before. The move triggered something in me. I felt liberated, free to go anywhere my imagination took me. And of course it took me into songwriting and performing. But I was always aware on some level that I was not really from the South. I felt a bit like an outsider, like a guest. That outsider point of view turned out to be something of an asset for me as a writer, I think. I wrote about other people. I searched for the odd point of view. I developed a sense of how others felt. I think that added a certain theatricality to my songs.
How important was literature and poetry in your life? What is the relationship of music with poetry?
I have always read a lot. Besides being a cheap source of entertainment, literature gives constant lessons in how to tell a story. In high school I read Robert Browning's, My Last Duchess. It was a dramatic monologue and it floored me. An Italian Duke is speaking of his former, now dead wife. He is cruel and monstrous but totally unaware that he is seen by others as anything but highly civilized. That fascinated me and I have used that technique in many songs. A character is baring his true soul without being the slightest bit aware of it. Jerusalem Tomorrow, and Robert Ford and Jesse James are songs that employ that technique.
Which meetings have been the most important experiences for you? What is the best advice ever given you?
When I moved to North Carolina I met a woman, Marcia Wilson, who started a club called the Cat's Cradle in Chapel Hill, North Carolina. Marcia and I were very close and the Cradle became the center of the music scene in that area. It was a magnet for all the musicians and song writers at that time. It became the center of my life. I met two Carolina musicians there, Tommy Goldsmith and Steve Runkle. They were the first guys I knew to head off for Nashville. That put the idea in my head and a year or so later I moved to Nashville myself. "Go to Nashville" is the best advice I was ever given.
"The Blues is a musical form that demands honesty. It's forms are simple but in no way easy. It can be a lifetime's work to figure out how Howlin' Wolf does what he does."
From the musical point of view what are the differences between: Music City and the other local scenes?
To move to Nashville was probably the first adult decision I had made in my life. All musicians in Nashville come from some place else. They were part of a local scene and had done well. Someone had said to them, "You're good. You should go to Nashville." Once you get to Nashville you've become a small part of a large and important scene. The stakes are immediately higher. You don't move to Nashville to make friends. You come here to make your mark. The musical bar is set high here. If you are a guitar player you've got to be really good to be noticed. Same for songwriting. Not all the music and songs are great that come out of Nashville. Some of the worst stuff I have ever heard, I heard in Nashville. But the ideal is transcendent. I'm proud to be a part of the scene here.
What do you miss most nowadays from the music of past? What are your hopes and fears for the future of?
I grew up in the sixties and the music I heard was wonderful. The radio was a magic box that voiced all my hopes and dreams. What was popular in the culture, The Beatles, Aretha Franklin, Bob Dylan, was the best the culture had to offer. That was the key: the culture was offering the music. It was not dictated by the great corporate beast. Labels could not predict a Jimi Hendrix or a Janis Joplin. They could only react when these strange folks appeared on the scene. It was heavenly music but it was risky business. The powers that be finally prevailed in their attempts to run the show. The beautiful wild horses are safely locked in the stables. Some time in the future the pendulum will swing and the wild horses will escape. We'll ride them someday.
"I play a folk based brand of rock. Early exposure to blues, especially Jimmy Reed, influenced me."
What do you learn about yourself from the blues and what does the blues mean to you?
The Blues is a musical form that demands honesty. It's forms are simple but in no way easy. It can be a lifetime's work to figure out how Howlin' Wolf does what he does. Every culture in the world has some form of the blues. You can't master the blues but you have to confront it, you have to deal with it. To me it is the place where music and songs begin.
What are the lines that connect the legacy of Blues with Folk and continue to Rock and Country music?
I have noticed in my songwriting that I will write a simple song, then a less simple song, then a complicated song and then I get stuck. I have to go back to the simple song. I try to write a song that Buddy Holly might have liked. I try to write a bluesy song. When I go back to the simple, I feel like someone who has been away for a long time and is returning home for Christmas.
What would you say to William Shakespeare and what would you like to ask Johnny Cash?
In the presence of William Shakespeare or Johnny Cash I would be very, very quiet and listen very, very hard to what they had to say. I might at some appropriate moment offer my deepest thanks.
Then I'd steal their notebooks.
Let's take a trip with a time machine, so where and why would you really wanna go for a whole day..?
I think I would like to travel to Vienna circa 1910. I'd check out the art. Look up Freud. Stop World War I from happening. If that didn't work out I could at least get a good cup of coffee and some great pastry. Wish me luck.
David Olney - official website
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text:
Выкно () — пассажирская и грузовая железнодорожная станция близ села Будзишевице в гмине Будзишевице, в Лодзинском воеводстве Польши. Имеет 2 платформы и 3 пути.

Станция на железнодорожной линии Лодзь-Калиская — Дембица, построена в 1910 году, когда эта территория была в составе Царства Польского.

Ссылки
 Информации в базе atlaskolejowy.pl
 Информации в базе bazakolejowa.pl
 Информации в базе semaforek.tk

Железнодорожные станции, открытые в 1910 году
Железнодорожные станции в Лодзинском воеводстве


text:
The 13 albums Leeds gave the world
Many of the songs featured on these albums could be the soundtrack to your life.
Friday 12 April 2019 13:52
And they all have one thing in common - they were all released by pop acts hailing from, or with connections to, Leeds. READ MORE: 30 unseen photos from inside Leeds nightclubs in the 1990s
1. Employment, Kaiser Chiefs
Released in March 2005 it peaked at number two in the charts almost a year after its release, due to the band's success at the Brit Awards.
2. Entertainment\! - Gang of Four
The debut album by this English post-punk band released in September 1979. It draws on punk but also incorporates the influence of funk, dance music, reggae and dub.
Linda Chasteau
3. Present Tense - Wild Beasts
The fourth studio album by Wild Beasts. It was preceded by the single Wanderlust released on the same day in February 2014.
jpimedia
4. Kaleide - Sky Larkin
Released in 201 by this indie rock band who are Katie Harkin (vocals, guitar, keys)'Nestor Matthews (drums) and Michael Matthews (bass).


text:
Achromatopsia: The CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14
Wojciech Wiszniewski, Richard Alan Lewis, James R. Lupski
Achromatopsia (ACHM) or rod monochromacy is an autosomal recessive and genetically heterogeneous retinal disorder. It is characterized by a lack of color discrimination, poor visual acuity, photodysphoria, pendular infantile nystagmus, and abnormal photopic electroretinographic (ERG) recordings with preservation of rod-mediated function. Mutations in three known genes are causative; including genes for the α and β subunits of the cyclic nucleotide-gated cation channel (CNGA3 and CNGB3, respectively) and cone photoreceptor transducin-NNAT2. We investigated the prevalence of mutations in achromatopsia-causing genes in a cohort of 16 families with both clinical and electrophysiologic evidence consistent with autosomal recessive transmission, including one subject with achromatopsia and maternal isodisomy for chromosome 14. The most frequent mutation, p.T383fsX in CNGB3, accounted for 75% (18/24) of disease-associated alleles; intragenic SNPs in unrelated patients revealed transmission of a common haplotype consistent with a founder effect. Homozygous p.T383fsX mutation in CNGB3 that maps to chromosome 8 was detected in a patient with achromatopsia and systemic features associated with uniparental disomy (UPD) of chromosome 14. Two novel variants, p.R223G and p.A621E were found in CNGA3. We conclude that CNGA3 and CNGB3 mutations are responsible for the substantial majority of achromatopsia. Furthermore, the CNGB3 mutation p.T383fsX is a predominant mutation, results from a founder effect, and is responsible for the ACHM in the original clinical report of UPD 14.
Human Genetics
Uniparental Disomy
Color Vision Defects
Founder Effect
Cyclic Nucleotide-Gated Cation Channels
Transducin
Pathologic Nystagmus
Retinal Cone Photoreceptor Cells
Chromosomes, Human, Pair 8
Haplotypes
Wiszniewski, W., Lewis, R. A., & Lupski, J. R. (2007). Achromatopsia: The CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14. Human Genetics, 121(3-4), 433-439. https://doi.org/10.1007/s00439-006-0314-y
Achromatopsia : The CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14. / Wiszniewski, Wojciech; Lewis, Richard Alan; Lupski, James R.
In: Human Genetics, Vol. 121, No. 3-4, 05.2007, p. 433-439.
Wiszniewski, W, Lewis, RA & Lupski, JR 2007, 'Achromatopsia: The CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14', Human Genetics, vol. 121, no. 3-4, pp. 433-439. https://doi.org/10.1007/s00439-006-0314-y
Wiszniewski W, Lewis RA, Lupski JR. Achromatopsia: The CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14. Human Genetics. 2007 May;121(3-4):433-439. https://doi.org/10.1007/s00439-006-0314-y
Wiszniewski, Wojciech ; Lewis, Richard Alan ; Lupski, James R. / Achromatopsia : The CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14. In: Human Genetics. 2007 ; Vol. 121, No. 3-4. pp. 433-439.
@article{5e1242681a44456291e5fa5a5b210f86,
title = "Achromatopsia: The CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14",
abstract = "Achromatopsia (ACHM) or rod monochromacy is an autosomal recessive and genetically heterogeneous retinal disorder. It is characterized by a lack of color discrimination, poor visual acuity, photodysphoria, pendular infantile nystagmus, and abnormal photopic electroretinographic (ERG) recordings with preservation of rod-mediated function. Mutations in three known genes are causative; including genes for the α and β subunits of the cyclic nucleotide-gated cation channel (CNGA3 and CNGB3, respectively) and cone photoreceptor transducin-NNAT2. We investigated the prevalence of mutations in achromatopsia-causing genes in a cohort of 16 families with both clinical and electrophysiologic evidence consistent with autosomal recessive transmission, including one subject with achromatopsia and maternal isodisomy for chromosome 14. The most frequent mutation, p.T383fsX in CNGB3, accounted for 75{\%} (18/24) of disease-associated alleles; intragenic SNPs in unrelated patients revealed transmission of a common haplotype consistent with a founder effect. Homozygous p.T383fsX mutation in CNGB3 that maps to chromosome 8 was detected in a patient with achromatopsia and systemic features associated with uniparental disomy (UPD) of chromosome 14. Two novel variants, p.R223G and p.A621E were found in CNGA3. We conclude that CNGA3 and CNGB3 mutations are responsible for the substantial majority of achromatopsia. Furthermore, the CNGB3 mutation p.T383fsX is a predominant mutation, results from a founder effect, and is responsible for the ACHM in the original clinical report of UPD 14.",
author = "Wojciech Wiszniewski and Lewis, {Richard Alan} and Lupski, {James R.}",
journal = "Human Genetics",
T1 - Achromatopsia
T2 - The CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14
AU - Wiszniewski, Wojciech
AU - Lewis, Richard Alan
AU - Lupski, James R.
N2 - Achromatopsia (ACHM) or rod monochromacy is an autosomal recessive and genetically heterogeneous retinal disorder. It is characterized by a lack of color discrimination, poor visual acuity, photodysphoria, pendular infantile nystagmus, and abnormal photopic electroretinographic (ERG) recordings with preservation of rod-mediated function. Mutations in three known genes are causative; including genes for the α and β subunits of the cyclic nucleotide-gated cation channel (CNGA3 and CNGB3, respectively) and cone photoreceptor transducin-NNAT2. We investigated the prevalence of mutations in achromatopsia-causing genes in a cohort of 16 families with both clinical and electrophysiologic evidence consistent with autosomal recessive transmission, including one subject with achromatopsia and maternal isodisomy for chromosome 14. The most frequent mutation, p.T383fsX in CNGB3, accounted for 75% (18/24) of disease-associated alleles; intragenic SNPs in unrelated patients revealed transmission of a common haplotype consistent with a founder effect. Homozygous p.T383fsX mutation in CNGB3 that maps to chromosome 8 was detected in a patient with achromatopsia and systemic features associated with uniparental disomy (UPD) of chromosome 14. Two novel variants, p.R223G and p.A621E were found in CNGA3. We conclude that CNGA3 and CNGB3 mutations are responsible for the substantial majority of achromatopsia. Furthermore, the CNGB3 mutation p.T383fsX is a predominant mutation, results from a founder effect, and is responsible for the ACHM in the original clinical report of UPD 14.
AB - Achromatopsia (ACHM) or rod monochromacy is an autosomal recessive and genetically heterogeneous retinal disorder. It is characterized by a lack of color discrimination, poor visual acuity, photodysphoria, pendular infantile nystagmus, and abnormal photopic electroretinographic (ERG) recordings with preservation of rod-mediated function. Mutations in three known genes are causative; including genes for the α and β subunits of the cyclic nucleotide-gated cation channel (CNGA3 and CNGB3, respectively) and cone photoreceptor transducin-NNAT2. We investigated the prevalence of mutations in achromatopsia-causing genes in a cohort of 16 families with both clinical and electrophysiologic evidence consistent with autosomal recessive transmission, including one subject with achromatopsia and maternal isodisomy for chromosome 14. The most frequent mutation, p.T383fsX in CNGB3, accounted for 75% (18/24) of disease-associated alleles; intragenic SNPs in unrelated patients revealed transmission of a common haplotype consistent with a founder effect. Homozygous p.T383fsX mutation in CNGB3 that maps to chromosome 8 was detected in a patient with achromatopsia and systemic features associated with uniparental disomy (UPD) of chromosome 14. Two novel variants, p.R223G and p.A621E were found in CNGA3. We conclude that CNGA3 and CNGB3 mutations are responsible for the substantial majority of achromatopsia. Furthermore, the CNGB3 mutation p.T383fsX is a predominant mutation, results from a founder effect, and is responsible for the ACHM in the original clinical report of UPD 14.
JO - Human Genetics
JF - Human Genetics


text:
Did the 911 investigation get it wrong? Maybe, says group
6 months ago Ian Harvey
When it comes to conspiracy theories and polarized thoughts, few incidents trigger controversy like the 911 collapse of the World Trade Centre and a third building, known as Building WTC 7.
Principle Curator Ian Harvey wrote this story in 2020 about a group of engineers and architects and victim family members who say the scuience doesn't support the finding of an investigation that claimed fire weakened the structural steel and triggered the floor-by-floor collapse.
It's important to note that they don't claim that any group or person deliberately set explosives or did something else to trigger the collapse of WTC7 just that from an engineering and science standard the findings do not hold true and that there was nothing wrong with the integrity of the design or construction of the building.
The Architects & Engineers for 9/11 has filed a Request for Correction with the National Institute of Standards and Technology (NIST) following a new and detailed four-year analysis by a team at the University of Alaska Fairbanks.
It says the World Trade Centre building 7 collapse was a "near-simultaneous failure of every column in the building" and dismissed the NIST finding that heat from the fire caused beams to "walk off" their moorings.
The Sept. 11, 2001 is tragedy of two hijacked planes hitting WTC 1 and WTC2 that morning sent debris tumbling onto WTC and NIST claimed that embers ignited a fire which then caused the 47-storey building to collapse on itself at 5.20 p.m. hours after the initial incident.
WTC 7 show in the compex
"We have filed a request for correction because the NIST report is wrong," says Ted Walter, spokesperson for group of 3,000 engineers, scientists and architects, including more than a dozen Canadians which paid US$316,000 for the study. "From an engineering perspective it is imperative to understand how and why this building came down under design load conditions."
The study says NIST made some fundamental errors in how engineers estimated the rigidity of the outside building frame and that the heat generated by the fire did not trigger "thermal movements" at a critical base plate support.
Further, the group, which includes families of those killed, asserts that the investigation is flawed and that the conclusions as to what happened must be based on "science and engineering" and accept that controlled demolition is a plausible cause. For expediency and because it was not hit by a plane, the study looked only at WTC 7 not the other two but AE911T has long claimed all three were subject to something beyond heat induced failure.
"The report notes that the outside frame was more flexible than the inside framing which is where the elevator shafts were," says McMaster University professor emeritus of civil engineering, Robert Korol, a fellow of the Canadian Society of Civil Engineering one of two peers who reviewed the UAF study. "Under the conditions described the displacement of the outside steel would have been only 1 inch, not the 6.25 NIST claimed and not enough to cause failure."
Further, he says, the debris from WCT1 which fell 943 feet to WCT 7 did not attain sufficient mass to cause structural damage to the steel in that building.
Diagram showing steel failure
The bottom line, he says, is that the NIST report is flawed and of no value to future engineering or architectural learning.
The Alaska report adds new momentum to long standing claims by the AE911T that all three of the buildings should not have collapsed in the spectacular and deadly manner they did. Further, and Prof. Korol underlines this, there was nothing in the offices beyond basic desks, chairs, computers and paper that would be of a of such a combustible nature so as to feed a fire and raise the temperature to above 1,400C and melt the steel structure.
"We don't even know if the steel was fireproofed," says Prof. Korol.
The group makes no assertion as to why it may have been a "controlled demolition" and says its only interest is in ensuring that there's no need to rethink the structural steel design of high rises because the design was not at fault.
UAF civil engineering professor Leroy Hulsey, principal investigator, his research assistants, Feng Xiao, now an associate professor at Nanjing University of Science and Technology and Zhili Quan, now a bridge engineer for the South Carolina Department of Transportation, found that the design standard of the building was no exceeded by the fire and that simultaneous and controlled demolition caused the structural steel to fail.
"Fires could not have caused weakening of displacement of structural members capable of initiating any of the hypothetical local failures alleged to have triggered the total collapse of the building," the report states. "Not could any local failures, even if they had occurred, have triggered a sequence of failures that would have resulted in the observed total collapse."
The NIST report held that lateral support beams buckled because of thermal expansion from the fire and because they had "nowhere to go" and thus deformed and weakened the structural integrity. Other failures were triggered when joists and means "walked off" their connections, NIST found.
It was also the first NIST finding of a high rise collapse from thermal deformation caused by fire which the 125-page Alaska report disputes.
It presents arguments showing it was a simultaneous global failure not a localized failure causing a domino effect.
Prof. Hulsey et al, argue that the collapse was straight down in a pancake fashion with about 2.25 to 2.5 seconds for free fall acceleration.
"In a typical building collapse (given a localized structural steel failure) WTC7 would be expected to axial rotation and bending of members, resulting in a disjointed, asymmetrical collapse at less than free-fall acceleration," the report states.
An initial report in 2002 by The Federal Emergency Management Agency (FEMA) pointed to a steel member recovered from WTC 7 with corrosion from a combination of oxidation and sulfidation at 1,000°C, resulting in the formation of a liquid eutectic
"Researchers have hypothesized that the presence of thermate, which is a form of thermite incendiary that includes sulfur, would explain the sulfidation and formation of a liquid eutectic," the report says noting FEMA found there weren't enough combustibles to generate enough heat to weaken the steel and speculated diesel fuel stored in the basement was somehow being pumped through severed pipes and fed the flames. However, NIST later dismissed that hypothesis.
The study team undertook extensive computer and physical modeling, paying particular attention to the area around Column 79 which had been identified as the critical juncture of failure.
Their conclusion is that Columns 79, 80, and 81 did not fail at the lower floors of the building and were not subject heat above floor 30 because there were no fires there.
Even if they did, they would not trigger a horizontal progression of core column failures and the team was unable to find any other plausible cause for the progressive sequence of failures. ?
Tags: 911, Architects and Engineers for 9/11, collapse, conspiracy, science and engineering, World Trade Centre, WTC7
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4 days ago Ian Harvey
2 months ago Keith Beckles


(1) Lecture by Dan Kahan – On Thursday evening, Dan Kahan of the Yale University Law School gave a talk titled "How to Communicate Climate Change." I have seen Professor Kahan speak before, when he was a panelist at the ScienceOnline Climate conference in DC in August 2013 (my summary of the panel is here), and I was pleased to have the opportunity to see him give a full lecture on his work. Professor Kahan heads up the Cultural Cognition Project at Yale Law School, an effort that studies how cultural values shape public risk perceptions and related policy beliefs. This was not his first time speaking at Penn State, and you can see his notes and a video from his visit back in October 2013. I look forward to reading more about the Southeast Florida Regional Compact Climate Change and reviewing Prof. Kahan's work emphasizing the need to communicate normality. One of his take-home messages was NOT to find an expert that looks like one of "them" (the audience you are communicating to/with) or an actor that makes an appearance and reads from a script, but to find "one of them" if you want the community to listen to climate change.
(2) A visit to the PA Chapter of The American Chestnut Foundation office and orchards – I had the opportunity Friday morning to meet with Stephanie Bailey, the Chapter Administrator, in her office at the Forestry Resources Lab on campus. I had been introduced to this organization and its work through the volunteering I have been doing at the chestnut nursery at Tyler Arboretum, and I learned even more when I spoke at the PA-TACF Fall Meeting back in November. Stephanie was so kind to take the time to show me around their facilities, including the greenhouses, and then we went out to the orchards for a tour (Penn State has 3 chestnut orchards, out of the 150-200 that exist across Pennsylvania!). I'll be blogging about my visit with Stephanie soon on my Journeys of Dr. G at Tyler Arboretum blog to share more the chestnut story and the journey of Tyler's harvested chestnuts with those followers.
Just one section of one of the chestnut orchards on the Penn State University Park campus.
(3) Session with Robbie Melton – Dr. Robbie Melton is the associate vice chancellor of mobilization and emerging technology with the Tennessee Board of Regents – and she calls herself an app-ologist. She is the afternoon keynote speaker for the Penn State Teaching and Learning with Technology Symposium, but on this afternoon, she held a special small group session and gave us a preview of some of the topics she would be sharing in her keynote, and we learned about so many tech tools and apps available for education. But here are some of her important take-home messages: (1) if students are coming with mobile technology (and they are!), we are going to have them use it; (2) we need to look at the possibilities in our classrooms, not policies and standards of our universities; (3) we need to be easy, be a change agent… and oh yes, life is good! I will have more about her tools and suggested approaches to using mobile technology when I blog about her conference keynote. For now, I encourage you to check out her website that allows you to search over 50,000 apps that can be used for educational purposes!
On Saturday, the TLT Symposium (that stands for Teaching and Learning with Technology Symposium) begins! I'm looking forward to learning about innovations and integrations with technology from fellow Penn State faculty members.


This past summer, Berluti hosted a poolside cocktail party to show the Spring-Summer 2017 collection. The Parisian shoemaker took this opportunity to show what the house's lifestyle is all about: skateboarding in a polo shirt on the paths of the formal garden, sporting swimwear armed with a Venezia leather covered Frisbee, or a workout session in Fast track sneakers. The mood is all about lightness, outdoor, easy lifestyle. Summer will be here again soon and Berluti is providing everything to take the travelling man right through the season.
The sky lends its hues to the Spring-Summer 2017 ready-to-wear collection designed by the Berluti studio. Pure white, sunshine yellow, turquoise, navy blue, rust red and deep brown are all nods to day-to-evening wear designed to meet all the whims and requirements of a nomadic man. The B-Way leather blouson, zipped fleece-lined hoodie, two-tone jersey-knit polo shirt, tailored denim shirt and Serge trousers offer a very casual or more formal attire, which is always immaculate, to suit every circumstance.
This summer, Berluti presents its finest outwear equipment with the new lifestyle collection in the shape of fun, quirky objects such as skipping rope, dumbbells, beach rackets or a petanque set revisited in Venezia leather. Berluti's emblematic leather is also hand stitched around a football or air-brushed with a sunset on the Time-Off backpack.
Hybrid shoes accessorise this bright all-road look. These designs have been created to rise to every occasion with flair. Fast Track sneakers, drawing its design credentials from running shoes and the shoemaking tradition, is available in pure white Vitello Unico leather. Graduated sunset blue injects a fresh touch to the shoemaker's emblematic Playtime sneaker. The Matteo design offers a stylish take on the skateboard look with its one-cut Venezia leather upper secured in the classic manner to a vulcanised rubber sole.
In Miami perhaps, then Formentera, Porto Ercole, and Los Angeles. The aim is to travel where leasure will take him. The House is following the contemporary hedonist from wide expanses of sand to blue waves. This gent is attentive to his personal style and freedom of movement. His hybrid, relaxed outerwear meets all his requirements effortlessly, leaving ready for anything.


(20246-38-145-6, John Melton Collection, OHS).
Charles Burnham "Bud" Wilkinson, born April 23, 1916, in Minneapolis, Minnesota, was only thirty-one when he became the University of Oklahoma (OU) head football coach in 1947. He created a college football empire during his seventeen years with the Sooners. His Sooner teams earned a 145–29–4 record, including five undefeated seasons, three national championships, and a national record of forty-seven consecutive games without a defeat from 1953 through 1957. His 1948–50 teams won thirty-one straight, and his Sooners won national championships in 1950, 1955, and 1956. Oklahoma also won fourteen conference championships under Wilkinson, plus seven of nine bowl games.
Wilkinson played football and hockey at the University of Minnesota, earned his master's degree at Syracuse University, and served in the U.S. Navy during World War II. He coached football with Jim Tatum at the Navy's Jacksonville, Florida, program and followed Tatum to the University of Oklahoma in 1946. When Tatum moved to Maryland in 1947, Wilkinson became head coach at OU. He also became athletic director at Oklahoma.
In 1964 he resigned as head coach and ran unsuccessfully against Fred Harris in the race for a U.S. Senate seat. He had earlier served as head of Pres. John F. Kennedy's national physical fitness campaign, and during the Nixon administration he was a White House advisor. Wilkinson coached the St. Louis Cardinals in the National Football League during the 1978–79 seasons and later served as a sports analyst and broadcaster for ABC and ESPN. He spent several years on the boards of the Lifetime Sports Foundation and the Planned Marketing Association, and he was founding president of the Public Employees Benefit Services Corporation, which he served as chairman of the board until 1982. Wilkinson and his wife, Donna, had two sons. Coach Bud Wilkinson, elected to the College Football Hall of Fame in 1969, died in St. Louis, Missouri, on February 9, 1994, of congestive heart failure.
Daily Oklahoman (Oklahoma City), 10 February 1994.
"Bud Wilkinson," Vertical File, Archives, Oklahoma Sports Hall of Fame, Oklahoma City, Oklahoma.
Jay Wilkinson and Gretchen Hirsch, Bud Wilkinson: An Intimate Portrait of an American Legend (Champaign, Ill.: Sagamore Publishers, 1994).
Max Nichols, "Wilkinson, Charles Burnham," The Encyclopedia of Oklahoma History and Culture, https://www.okhistory.org/publications/enc/entry.php?entry=WI013.


I am new to the forum and my main interest is 20's battery radios. I am starting to feel like it was an unfortunate choice as it seems there isn't much interest among current radio collectors/restorers in these radios, which means there isn't much help for someone like me who is fairly new to this hobby. I was wondering how many users of this forum have any interest in the radios of this era?
Battery radios found me in '63, when an estate was given to me. My early communication with other collectors began in '74 either at meets or through publications.
I still find them intriguing, especially the not so common RF sets and reflexes, in particular well crafted homemade or kit receivers.
There are a lot less battery tube radios in that vintage, just because of the invention of Radio had no commercial stations to start with, one was located in Madison WI. As an experimental University broadcaster WHA. The other was KDKA the only other one that started after WHA. Most receivers were home built or kits to start with, farmers started getting interested to hear local farm news, and weather forecasts. Since most rural communities had no electrical power available the only way was to use batteries. I imagine most radios were quite costly and therefore out of the average persons cost.
I have no knowledge of production numbers. As you have a interest you may find that even newer sets have the same basic functions and wiring. So if you need assistance in troubleshooting were do have some help here. Don't be discouraged as there are many books from that era that deal with problems encountered.
There are other forums such as RadioMuseum.org and Antiqueradio.com. are another resource.
Welcome to our forum, and participate in several different topics as your interest increases.
I have had a lifelong interest in the 1920s broadcast radios starting when I was a teenager after I got a start in ham radio. I was one of the younger collectors at the time when most of the fellows were much older experienced radio men and such. I am 61 now. I began collecting radios, tubes-lots of 201A tubes, literature, test equipment and so on so if you have any questions or want help just ask here on the forum.
I don't have a lot of radio stuff now after a major move from back east but I still have the interest. I have recently got back into the hobby and have picked up a couple of Freed-Eisemann sets-one of my old favorites. I hope to get another finances pending. I have also started looking around for the battery tubes like my favorite the fairly common Cunningham CX-301-A. There were also a lot of independent tube manufacturers out there back in the 20s and 30s and finding them is part of the fun too. I have picked up some 201A types recently-with mixed results.
Some of my tube buys have turned out to be very good. Others not so good-weak tubes or arriving with shipping damage-broken envelopes, shorts or open filaments, etc. There seems to be a wide variability in the quality and suitability for use of these tubes but this has been the case since I started picking them up more than 40 years ago. Amazing that they still work after nearly 100 years! So since the tubes can very so much some experimenting is necessary in trying them out in the various sections and sockets of the receiver to see where they will function best.
My past experiences here: the better, hotter tubes are needed in the RF amplifier section. Next best in the detector socket, and then the lower quality ones seem to do ok in the audio amp section of the receiver. This varies of course so if you get squeaks and oscillations and motorboating and what not you might need to shuffle them around some more or try some other tubes.
I enjoy testing tubes and think grading the tubes helps and bears out in actual radio performance. I just picked up a nice WWII vintage Hickok 540 tester which is very good for the mid 1940s and earlier type of tubes it was designed for. It is also fun to use. I don't have much test equipment at present but I hope to pick up some. I am looking into condenser/capacitor checkers right now but haven't made a decision yet on what to get. It is hard to decide. So many different makes and models of checkers. A lot of them are basically the same circuit though but the features can vary. I recently picked up some parts, tubes, and chassis to fit the various Eico 950 models anticipating I might go in that direction. Radiotvphononut uses a Heathkit C-2 and Eico 950B with good results. It is fun to watch him at work. I've tried to find a C-2 but no luck so far. I did get a manual for one.
So good luck and ask for help when you need it.
Using a tube tester than can test for gas is helpful, gassy '01as can go in the detector if the detector supports a combination of separate filament control and easy access to the grid leak.
A good RF generator that can get down to 50khz for the early supers is helpful, so is an old school audio scope.
I did forensics on transformer failures and found that corrosion is about 25% and (blown open) about 75% of the time. The blown ones are from use of the radio during electrical storms where the amp is operating at maximum, the abrupt cutoff of the tube from the static pulse causes a high voltage kickback in the transformer burning open. Forensics found microscopic copper balls and the ends of the wire rounded from the arc. Acids from the arc eaten through to the above and below layer. Sets that have "C" batteries stored in the cabinet generally will have a higher incidence of bad transformers too. The tar battery sealant contracts and the fumes creep into the tender windings.
I sold my place and moved out of Lyncburg, Virginia about 6 1/2 years ago to Oroville, CA where I still have some family.
I had a pretty good radio setup back in Lynchburg. Lots of test equipment, parts, tubes, boatanchors, microphones, am/cw transmitters, manuals, radio literature and so on. Also some older sideband gear like RL Drake. Military, commercial and older ham equipment made up most of the gear. I was frequently on the air on AM Phone at 3885 kHZ-almost a nightly fixture in fact.
I had a good supply of the older tubes and parts going back to the 1920s in Lynchburg but just a very limited supply of battery sets of the 1922 to 1926 era. I did have a working 1927 RCA Radiola 18, a Radiola 33, a couple of RCA R-100A speakers, and Atwater Kent cone and horn speakers. I was mainly concentrating on short wave, war surplus and older ham radio gear at that time.
I got into collecting battery sets probably around 1970. I built up a fairly good collection for a young person on a limited budget.
I had a friend, (Bill Wakefield) that I went to the CHRS meets with when I was living in the Bay Area (1970s). We used to go up to see Paul Giganti who was a well known collector at the time and an early AWA member. Paul was also a very knowledgeable dealer in antique radios and I bought quite a few sets from him including my first tube checker that was a WWII vintage Navy Hickok 550X.
I used to frequent some of the radio surplus houses that were in the bay area back then. In addition to the CHRS meets I was able to make the trip to a few of the Southern California Antique Radio Society (SCARS) meets. I also started going to hamfests about that time which was a real boon to collecting.
Well, I have fun watching some of the youtube radio repair videos. RADIOTVPHONONUT is my favorite and his channel name gives one a good clue on what he likes to fix. I guess he is in his early 40s. Nowadays, I would call him a young person to be in this hobby. He does not appear on camera but his narration is good and his stories are interesting-he would be a good one on 75 meters AM Phone.
I don't know if your familiar with the Gernsback publications of Radio Service Manuals, so I am providing a link to you to Help.
The first volume has Atwater Kent Schematics and some Instructional comments.
I have not found a battery set of that vintage close to my Location, But there are a few Radio Clubs that are active in Tacoma and Seattle areas.
I do have a RCA Radiola 60 ( 1928 ) that I got several years ago, decided to strip off the cabinet and only used acetone and # 400 steel-wool.There was enough Lacquer still on the surface that wiping it with a cloth provided it with a beautiful finish. That was my first project. I never got around to testing it or repairing it. Its a dust collector right now but it still is on my TO DO list.
Here's a link to a member discussion on a Neutrodyne needing a solution and being solved!
Thanks for the link Cliff. I have heard of the famous Gernsback manuals. I have an original Atwater Kent service manual I use but I have found you can never have enough resources.


text:
Countries With the Worst Internet in the World
Relying on free WiFi is something that international travelers are forced to do in the majority of destinations due to the extortionate costs of data roaming. Unfortunately, that also means sometimes having to deal with slack foreign internet speeds - here are the top 5 worst destinations for WiFi!...
Perhaps a little surprisingly economic super-giant India also garners a look-in on this list, even though it's slowly emerging as one of the planet's major tech giants. With that in mind and a whole host of other communications investments set for the future, don't expect this one to languish here long!
Nestled in the panhandle of West Africa, Nigeria hails in with another of the world's super slow internet connections. That means, despite efforts from the government to improve communications infrastructure here with satellite technology and the like, it's still a place you may want to think about taking your own data roaming gadgets to.
While Jakarta may be booming forth in an explosion of modern big business, the rest of Indonesia seems to be lagging a little behind—literally! In fact, it's estimated that just shy of 20% of households with internet access here are still suffering from 256Kb connections, while it's also thought that many of the rural areas in places like Sumatra and the Nusa Tenggara have no internet facilities at all!
If you're thinking about heading to the mysterious wilds of Central Asia this year, to case out the rolling steppe of the Kazakh mountains or the summit-shrouded streets of bustling Almaty, then you may want to think about grabbing a wireless router for internet on the go, because this former Soviet satellite state is a frequent chart-topper on lists of the world's slowest web speeds.
Surely Nepal gets a free pass on this one? After all, the vast majority of its backcountry is dominated by the mighty rises of the Himalaya, which is hardly somewhere that needs speedy internet shopping facilities or access to Facebook! Still, Kathmandu could do better, with an estimated 32% of inhabitants there still languishing at 256 kbps.
Find out more about how to stay connected cheaply when you travel from all of your different gadgets, wherever you are traveling to.
Check out our travel gadgets!
india -
kazakhstan -
nigeria -
Indonesia -
nepal -
wifi on holiday -
connectivity -
internet on the go -


The Lisbon Town Board voted to draft an RFP seeking developers for the 65-acre, town-owned Haass Land, in the first step in selling the land itself.
TOWN OF LISBON – The town board on Aug. 27 authorized Supervisor Linda Beal and Administrator Gina Gresch to put together a request for proposal (RFP) seeking buyers and developers for the 65-acre, town-owned Pauline Haass land.
The decision was unanimous, with the exception of Supervisor Marc Moonen, who was not present.
The town board ended its Aug. 16 meeting with many questions about the Haass land after discussing the possibility of the town forgoing a commercial real estate broker and advertising the sale of the land itself.
"I just don't want to go through another meeting on this where we don't decide what to do," said Town Chairman Joe Osterman.
Gresch prepared a draft RFP for the meeting, and town attorney Kathy Gutenkunst sat in to discuss the town's options. A big part of the concerns on Aug. 16 meeting were any liabilities the town could face by marketing the land itself.
The board discussed Gresch's draft RFP and decided that it would likely be trimmed down to two pages from Gresch's five-page draft, which was maybe too thorough, according to the board.
"This seems like a lot of additional work," said Supervisor Tedia Gamiño.
Gamiño's initial concern was over the lack of a solid marketing plan from developers and that it seemed they would not do much more than the town could do themselves.
Gutenkunst offered advice based on her experience in real estate transactions.
According to Gutenkunst, a broker could monitor offers, oversee deadlines, and ensure that the deal goes smoothly, managing the process so the seller — in this case the town — would not be bothered by it.
Gutenkunst also advised the town on Supervisor Linda Beal's involvement in the deal. Beal had offered to oversee the deal, drawing from more than 30 years of experience in real estate. Gutenkunst advised that Beal should act solely as a town supervisor in this case.
With the RFP, the town intends to set a deadline for formal offers and proposals and see what the market brings. If it does not receive a favorable proposal, the town would still have the option of searching for commercial and residential brokers.
The land, southwest of the corner of Lake Five and Hickory Roads, is currently zoned as A-10 agricultural. It is designated as a suburban density I residential district in the town's comprehensive development plan, meaning there would be 1.5 to 2.9 acres of land per dwelling unit.
The draft RFP describes the property as "ripe for development." It currently has private well and septic utilities and no improvements or wetland areas.
The land was bequeathed to the town by Pauline Haass in 1985 for the building of a library.
The town entered into an agreement with the village of Sussex for a joint library in 1987. Under that agreement, both municipalities would provide similar funding, and Lisbon would keep the balance of Haass' assets, including her land.
However, Sussex already had a library, which became the joint library.
The land sat undeveloped for more than 30 years until it came into the town's sole possession after a long legal battle with Sussex and the Pauline Haass Library Board.
The final settlement agreement in early 2017 involved the town first turning the Haass land over to the library and then purchasing the land for $175,000. Sussex would then buy the library's building and land on Main Street in Sussex also for $175,000. The land was valued at $650,000 at the time.
Town supervisors heard proposals from several real estate firms earlier this summer but were unable to agree on a broker. The proposals ranged from developments of 43 to 50 lots, and projections that the land could be sold for between $1 million and $1.5 million.
Osterman and Moonen voted in favor of accepting a proposal from Dan Scardino of Point Real Estate, with Gamiño and Beal voting against. Supervisor Rebecca Plotecher was absent from that meeting.
Under Scardino's plan, the land would be marketed in 43 single-family residential lots at a price of $1.2 million, with Point Real Estate receiving a 7-percent commission — a reduction of Scardino's normal 8-percent commission. He would approach developers rather than sending out mass mailings.
At that same meeting, Gamiño proposed expanding the search and looking for new marketing proposals. The motion failed in a similar split to the Point Real Estate vote, with Gamiño and Beal in favor and Osterman and Moonen opposed.
Kate Schroeder of the Luther Group said she would list the property at $25,000 an acre for a total of $1.62 million and would take a commission between 3 and 5 percent. Jerry Metzger of the Midwest Realty Group proposed listing the property at $23,029 per acre, for a total of $1.49 million, and take a 4.8 percent commission.
Metzger attended the Aug. 16 meeting with a new proposal to sell 50 to 55 1-acre well-and-septic lots for between $75,000 and $100,000. He said that by selling that many lots at a reduced price, the town would be able to sell the land faster and get more money in the process. In one scenario of this plan, 55 lots at $75,000 each could rbring more than $4 million, but would require a change in the comprehensive development plan.


text:
Home News	North Augusta's controversial monument makes national news
North Augusta's controversial monument makes national news
by The Insider December 5, 2018
written by The Insider December 5, 2018
Just a few weeks ago, CNN uncovered major concerns about the water supply in the small town of Denmark, S.C.
After a year-long investigation, CNN discovered that the state government was adding a substance known as HaloSan to one of the city's four wells in an attempt to regulate naturally occurring iron bacteria.
According to CNN's report, HaloSan is a chemical that's typically used as a disinfectant for pools and spas. Many experts believe it should not be added to drinking water.
It was big news that rocked the Palmetto State.
Well, it appears that CNN has a taste for South Carolina's controversies because two days after Thanksgiving, the national news network was back in the Palmetto State.
But this time, CNN stopped just across the Savannah River in North Augusta.
Its purpose was to interview North Augusta Mayor Bob Pettit about the controversial stone monument that has stood in the city's J.C. Calhoun Park since 1916 honoring Thomas McKie Meriwether, a white man who died in what is known as the Hamburg Massacre.
For those who aren't aware, the Hamburg Massacre was a violent clash that broke out in 1876 as armed white men attempted to take control of a predominantly black town with the same name.
The monument is meant to commemorate the lone white causality of the massacre, but the clash also left seven black men dead.
According to historical accounts of the massacre, an all-black regiment led by a man named Dock Adams was stationed in Hamburg, which angered a white paramilitary group known as the Red Shirts.
On July 4, 1876, hundreds of Red Shirts surrounded and eventually attacked the 84-member black militia regiment, killing seven black men.
After the massacre, Dock Adams testified before a congressional committee describing what he witnessed that terrible day.
He said that many of the black men who were killed during the massacre were executed.
"They called them out one by one and would carry them off across the railroad, and stand them up there and shoot them," Adams testified, adding that the white men were celebrating while killing the black men. "You could hear it all the time. 'By God! We will carry South Carolina now. About the time we kill four or five hundred men we will scare the rest.' Even before it begun you could hear, 'We are going to redeem South Carolina today!' You could hear them singing it on the streets, 'This is the beginning of the redemption of South Carolina.'"
Not a proud day in South Carolina's history.
But, according to the monument, Meriwether was a "young hero" who gave his life "maintaining those civic and social institutions which the men and women of his race had struggled through the centuries to establish in South Carolina."
The monument further states, "He exemplified the highest ideal of Anglo-Saxon civilization. By his death he assured to the children of his beloved land the supremacy of that ideal."
Needless to say, the Meriwether monument in North Augusta has attracted a great deal of attention after the controversial removal of several Confederate monuments around the country last year.
But in this case, the Meriwether monument isn't tied to the Civil War or the Confederacy, so that makes it an unusual case.
Pettit told CNN that, while he believes there is a state law (South Carolina's Heritage Act) that prevents the city from removing the Meriwether monument, he thought North Augusta could add to the monument by recognizing the black men who also died in the clash.
In the center of the town of North Augusta, South Carolina is a monument to Thomas McKie Meriwether, the one white who was killed in the 1876 Hamburg Massacre. (Tim Dominick/The State/MCT)
"It's an opportunity to look at something divisive for the community and hopefully make it a positive for the community," Pettit told CNN on Nov. 24, adding that he admits the monument clearly promotes white supremacy. "I've had nobody dispute it to me. And we just need to take positive action to remedy that situation, in my opinion."
Ironically, Pettit acknowledged that he, along with most North Augustans, was not even aware of the transcription on the monument.
"It had stood in the center of town for over a hundred years in a prominent location, and most people didn't pay attention to what it said," he told CNN. "I think a lot of people are uncomfortable because of it, knowing that's not what we think today."
As a result of the city's concerns over the monument, Pettit explained that North Augusta established a committee of three whites and three blacks who spent 14 months investigating the monument's history.
After the investigation, the mayor has recommended that additions be made the park and monument to recognize the seven black men killed in the 1876 massacre including James Cook, Allen Attaway, David Phillips, Albert Myniart, Moses Parks, Hampton Stephens and Nelder John Parker.
Pettit felt that the harsh language on the monument could be used as a "teaching tool, so that those white supremacy attitudes portrayed on the monument didn't happen again."
"It's educational to know that viewpoint existed, so that it's out in public and you can recognize that it's not consistent with the way we're thinking today," Pettit told CNN, adding that he would not recommend taking the monument down. "I think that's a one-and-done, where as this, I think, can have a positive effect for a long time. And I think in that regard we're much better off as a city to have this educational experience that will persist."
When it comes to controversial monuments in their towns, that's a pretty uncommon position for many mayors across this nation.
Keeping the monument, but still trying to tell the full story of the massacre might be an impossible task for Pettit and North Augusta.
2 hours ago by metrospirit #augusta #augustaga #downtownaugusta #greenestreet #metrospirit #whistlestop #brandondiallaw


Innovation—in your own life, or as a leader of others—requires an open mind, creativity, capability, resolve, and courage. Many leaders get stuck in the status quo because it's easier than tapping into these qualities in themselves or others. Beyond that, transformative change upsets our sense of normalcy, which can be uncomfortable. Yet you need not remain complacent. When you might be game to make a change—or when it's the right thing to do—unleash your imagination and courage. You may never feel "ready," but sometimes "willing" and "able" are just right for a start.
In what ways is innovation present or absent in your leadership today?
Considering the five factors (above), which ones do you tend to find more daunting than others?
Given your interest and capacity for innovation, what would need to be true for you to leave the status quo behind in the immediate future?


You can vary the amount of vegetables according to your taste.
2. Peel and quarter the onion, carrots and celery. Peel the garlic. Cut the chicken pieces into thirds.
3. Place chicken, onion, carrots, celery and garlic in a 13 x 9-inch pan and toss with olive oil. Roast in oven for 40-45 minutes or until wings and vegetables are browned. Remove from oven, add 1 cup water to the pan and let sit for 15 minutes.
4. Place 5 cups of water, roasted vegetables with water and all remaining ingredients in the bowl fitted with the mixer. Launch the P2 simmer program at 200°F for 1 hour 30 minutes, without the stopper.
5. At the end of the program, strain broth and reserve. Discard the chicken and vegetables.


text:
Eike Immel (* 27. November 1960 in Erksdorf, heute zu Stadtallendorf) ist ein ehemaliger deutscher Fußballspieler. Der Torwart gehörte als Nationalspieler bei den Weltmeisterschaften 1982 und 1986 und den Europameisterschaften 1980 und 1988 dem Kader an.

Karriere als Spieler

Vereine
Als 15-Jähriger verließ Immel seine Jugendmannschaft TSV Eintracht Stadtallendorf und wechselte in die Jugendabteilung von Borussia Dortmund. Für die Profimannschaft von Borussia Dortmund debütierte er am 12. August 1978 (1. Spieltag der Bundesliga-Saison 1978/79) als 17-Jähriger beim 1:0-Sieg gegen den FC Bayern München.

Er wechselte 1986 von Borussia Dortmund, für die er insgesamt 247 Bundesligaspiele bestritten hatte, als Nummer drei der A-Nationalmannschaft zum VfB Stuttgart. In der Saison 1991/92 feierte Immel mit dem Gewinn der deutschen Meisterschaft seinen größten Erfolg.

In der Saison 1995/96 gab sein Trainer Rolf Fringer dem Nachwuchskeeper Marc Ziegler den Vorzug. Immel entschied sich deshalb, den VfB zu verlassen und wechselte in die Premier League zu Manchester City.

Immel absolvierte 534 Bundesligaspiele und nimmt damit Platz sieben der Liste der Rekord-Spieler der Fußball-Bundesliga ein. 287 Spiele davon bestritt er für den VfB Stuttgart. Von den Torhütern hat nur Oliver Kahn mehr Liga-Spiele absolviert. Er ist der Bundesliga-Torhüter mit den meisten Gegentoren: insgesamt 829. Nach "Zu-Null"-Spielen belegt Immel mit 148 Partien ohne Gegentor Platz vier hinter Manuel Neuer, Oliver Kahn und Oliver Reck.

Seine Karriere musste er in England wegen eines Hüftleidens beenden.

Nationalmannschaft
Immel absolvierte von 1975 bis 1978 Länderspiele für die Nachwuchsmannschaften des DFB und am 8. November 1978 ein Länderspiel für die Amateur-Nationalmannschaft, die in Den Haag der Auswahl der Niederlande mit 0:2 unterlegen war.

Immel war Juniorenauswahlspieler und wurde bei der U-21-Europameisterschaft 1982 Vizeeuropameister.

Am 11. Oktober 1980 war er mit 19 Jahren der jüngste Torhüter, der je für eine deutsche Fußballnationalmannschaft antrat. Das 1:1-Unentschieden in Eindhoven gegen die Auswahl der Niederlande war sein Debüt. Er stand bei den Europameisterschaften 1980 und 1988 und den Weltmeisterschaften 1982 und 1986 jeweils im deutschen Kader, das EM-Turnier 1988 spielte er als Stammtorhüter durch. Bis 1988 stand Immel insgesamt 19 Mal im Tor der deutschen Nationalmannschaft, kehrte ihr aber nach einem Streit mit dem Teamchef Franz Beckenbauer den Rücken, da dieser im ersten Qualifikationsspiel zur Weltmeisterschaft 1990 gegen Finnland dem jungen Bodo Illgner den Vorzug gegeben hatte.

Immel wurde für den Gewinn des Europameistertitels 1980 mit dem silbernen Lorbeerblatt ausgezeichnet.

Erfolge als Spieler

Vereinsmannschaften
 Deutscher Meister (1): 1992 mit dem VfB Stuttgart
 DFB-Supercup-Sieger (1): 1992 mit dem VfB Stuttgart
 UEFA-Pokal-Finalist (1): 1989 mit dem VfB Stuttgart
 DFB-Hallenpokal-Finalist (2): 1989, 1993 mit dem VfB Stuttgart

Nationalmannschaft
 Europameister 1980 ohne Einsatz
 Zweiter der Weltmeisterschaft 1982, 1986 ohne Einsatz
 Zweiter der U-21-Europameisterschaft 1982

Karriere als Trainer
Seine Trainerkarriere begann Eike Immel beim württembergischen Verbandsligisten VfR Heilbronn, mit dem er 1999 als Vizemeister hinter der SpVgg Au/Iller in die Oberliga Baden-Württemberg aufstieg. Im März 2001 wechselte er in die Türkei, zunächst zu Beşiktaş Istanbul, wo er (wie auch bei den folgenden Stationen) unter Christoph Daum als Torwarttrainer arbeitete. Nach dessen Demission im Mai 2002 wechselte er im Oktober 2002 zum FK Austria Wien, ehe er zwischen Juli 2003 und Dezember 2005 beim türkischen Rekordmeister Fenerbahçe Istanbul tätig war und Volkan Demirel trainierte. Seitdem bei Immel jedoch Femurkopfnekrose diagnostiziert wurde, kann er seinem Beruf als Torwarttrainer nicht mehr nachgehen. Seit Sommer 2019 trainiert Immel die zweite Mannschaft von Eintracht Stadtallendorf in der Kreisliga A Marburg.

Fußballschulen
Im Jahr 2008 gründete Eike Immel die Eike-Immel-Torwartschule in Kassel. Laut Medienberichten ist dieses Projekt jedoch bereits im Jahr 2009 wieder "eingeschlafen". Im April 2013 eröffnete die 'Eike Immel Fußballschule' in Frankfurt, die aber zwischenzeitlich wieder geschlossen wurde.

Fernsehauftritte
Vom 11. Januar bis zum 24. Januar 2008 nahm Eike Immel an der dritten Staffel der RTL-Show "Ich bin ein Star – holt mich hier raus!" teil, bei der er den 5. Platz belegte.
Eike Immel trat 2008 auch bei Das perfekte Promi-Dinner, Schmidt & Pocher und Nachtcafé auf. Immel war dreimal in der Fernsehsendung Markus Lanz zu Gast. In der Sendung vom 8. Februar 2012 erklärte er, seit seiner Geburt auf dem linken Auge eine Sehfähigkeit von unter 20 % zu haben. Das räumliche Sehen habe er sich schon seit frühester Kindheit antrainiert, obwohl er "beim ersten Versuch, mit dem Finger in ein Wasserglas zu treffen, es sicher nicht schaffen würde". Am 13. Juni 2012 diskutierte er über das EM-Spiel Deutschland gegen die Niederlande. Sein dritter Besuch war am 11. September 2014. Am 2. Dezember 2014 war er Gast in der Sendung Menschen bei Maischberger. 2015 kämpfte er zusammen mit 26 anderen Kandidaten in der Sendung Ich bin ein Star – Lasst mich wieder rein! um einen Platz im Dschungelcamp 2016.

Musikaufnahmen
Zusammen mit seinem Dschungel-Kollegen Bata Illic nahm Immel die Single Wie ein Liebeslied auf, die am 29. Februar 2008 veröffentlicht wurde.

Am 26. Juni 2009 erschien sein Solo-Album Meine andere Seite.

Privates
Immel entstammt einer Landwirtsfamilie. Er ist Vater einer Tochter und eines Sohnes.
Im Jahr 1988 unterstützte er den Wahlkampf von Lothar Späth (CDU) in Baden-Württemberg.

Eike Immel gehört dem Kuratorium der Stiftung Jugendfußball an. Die Stiftung Jugendfußball wurde im Jahr 2000 von Jürgen Klinsmann, weiteren erfolgreichen Nationalspielern sowie den Dozenten des Fußball-Lehrer-Sonderlehrgangs gegründet.

Im April 2008 musste Immel Privatinsolvenz anmelden, weil er sich durch langjährige hohe Konsumausgaben finanziell übernommen hatte und Bauherrenmodelle im Totalverlust geendet hatten.

Seit 2016 lebt er wieder in seiner alten Heimat in Stadtallendorf. Sein alter Verein TSV Eintracht Stadtallendorf wurde auf ihn aufmerksam und unterstützte ihn bei der Rückkehr. Immel engagiert sich bei dem hessischen Fünftligisten in der Jugendarbeit.

Weblinks

Einzelnachweise

Fußballnationaltorhüter (Deutschland)
Fußballtorhüter (Borussia Dortmund)
Fußballtorhüter (VfB Stuttgart)
Fußballtorhüter (Manchester City)
Fußballtrainer (VfR Heilbronn)
Fußball-Torwarttrainer (Türkei)
Fußball-Torwarttrainer (FK Austria Wien)
Teilnehmer an einer Fußball-Weltmeisterschaft (Deutschland)
Fußballeuropameister (Deutschland)
Träger des Silbernen Lorbeerblattes
Deutscher Meister (Fußball)
Teilnehmer an Ich bin ein Star – Holt mich hier raus!
Schlagersänger
Deutscher
Geboren 1960
Mann


Necrotizing enterocolitis (NEC) is the most frequent and lethal disease of the gastrointestinal tract of preterm infants. At present, NEC is thought to develop in the premature host in the setting of bacterial colonization, often after administration of non-breast milk feeds, and disease onset is thought to be due in part to a baseline increased reactivity of the premature intestinal mucosa to microbial ligands as compared with the full-term intestinal mucosa. The increased reactivity leads to mucosal destruction and impaired mesenteric perfusion and partly reflects an increased expression of the bacterial receptor Toll-like receptor 4 (TLR4) in the premature gut, as well as other factors that predispose the intestine to a hyper-reactive state in response to colonizing microorganisms. The increased expression of TLR4 in the premature gut reflects a surprising role for this molecule in the regulation of normal intestinal development through its effects on the Notch signalling pathway. This Review will examine the current approach to the diagnosis and treatment of NEC, provide an overview of our current knowledge regarding its molecular underpinnings and highlight advances made within the past decade towards the development of specific preventive and treatment strategies for this devastating disease.
Necrotizing enterocolitis : new insights into pathogenesis and mechanisms. / Nino, Diego; Sodhi, Chhinder; Hackam, David.
In: Nature Reviews Gastroenterology and Hepatology, 18.08.2016.
Nino, Diego ; Sodhi, Chhinder ; Hackam, David. / Necrotizing enterocolitis : new insights into pathogenesis and mechanisms. In: Nature Reviews Gastroenterology and Hepatology. 2016.
N2 - Necrotizing enterocolitis (NEC) is the most frequent and lethal disease of the gastrointestinal tract of preterm infants. At present, NEC is thought to develop in the premature host in the setting of bacterial colonization, often after administration of non-breast milk feeds, and disease onset is thought to be due in part to a baseline increased reactivity of the premature intestinal mucosa to microbial ligands as compared with the full-term intestinal mucosa. The increased reactivity leads to mucosal destruction and impaired mesenteric perfusion and partly reflects an increased expression of the bacterial receptor Toll-like receptor 4 (TLR4) in the premature gut, as well as other factors that predispose the intestine to a hyper-reactive state in response to colonizing microorganisms. The increased expression of TLR4 in the premature gut reflects a surprising role for this molecule in the regulation of normal intestinal development through its effects on the Notch signalling pathway. This Review will examine the current approach to the diagnosis and treatment of NEC, provide an overview of our current knowledge regarding its molecular underpinnings and highlight advances made within the past decade towards the development of specific preventive and treatment strategies for this devastating disease.
AB - Necrotizing enterocolitis (NEC) is the most frequent and lethal disease of the gastrointestinal tract of preterm infants. At present, NEC is thought to develop in the premature host in the setting of bacterial colonization, often after administration of non-breast milk feeds, and disease onset is thought to be due in part to a baseline increased reactivity of the premature intestinal mucosa to microbial ligands as compared with the full-term intestinal mucosa. The increased reactivity leads to mucosal destruction and impaired mesenteric perfusion and partly reflects an increased expression of the bacterial receptor Toll-like receptor 4 (TLR4) in the premature gut, as well as other factors that predispose the intestine to a hyper-reactive state in response to colonizing microorganisms. The increased expression of TLR4 in the premature gut reflects a surprising role for this molecule in the regulation of normal intestinal development through its effects on the Notch signalling pathway. This Review will examine the current approach to the diagnosis and treatment of NEC, provide an overview of our current knowledge regarding its molecular underpinnings and highlight advances made within the past decade towards the development of specific preventive and treatment strategies for this devastating disease.


text:
Q: How to get two value in bootstrap range slider? I want to get the two values in range slider to insert in table using $_POST[] in php.
Is it possible not to use javascript? if not, feel free to answer. Thanks
HTML:
<form method="post">

     <!-- #1 range value set 1-2 -->
     <input id="slide_default" type="text" data-slider-min="0" data-slider-max="5" data-slider-step="1" data-slider-value="[0,1]" name="" />

     <!-- #2 range value set 3-5 -->
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     <input type="submit" name="btn_submit">

<form>

EXPECTED ARRAY OUTPUT:
Array (
        [0] => 1,2 //#1 range value
        [1] => 3,5 //#2 range value
      )

PHP:
 if(isset($_POST['btn_submit']))
 {
      // code here
  }

A: Try this:
<form method="post">

      <!-- #1 range value set 1-2 -->
      <input name="slide_default[]" type="text" data-slider-min="0" data-slider-max="5" data-slider-step="1" data-slider-value="[0,1]" />

      <!-- #2 range value set 3-5 -->
      <input name="slide_default[]" type="text" data-slider-min="0" data-slider-max="5" data-slider-step="1" data-slider-value="[0,1]"/>

      <input type="submit" name="btn_submit">

 <form>

PHP:
if(isset($_POST['btn_submit'])) {
    print_r($_POST['slide_default']);
}

Though I have not tested it, but I think this should work.


text:
Home / Video / Walking around Rovaniemi, July 2021, Finland [4K]
Title : Walking around Rovaniemi, July 2021, Finland [4K]
Viewed : 822
Walking around Rovaniemi, July 2021, Finland. Rovaniemi is the administrative capital and commercial centre of Finland's northernmost province, Lapland, and its southern part Peräpohjola. It is situated about 6 kilometres (4 miles) south of the Arctic Circle and is between the hills of Ounasvaara and Korkalovaara, at the confluence of the river Kemijoki and its tributary, the Ounasjoki. It is the second-largest city of the Northern Finland after Oulu, and, together with the capital city Helsinki, it is one of Finland's most significant tourist cities in terms of foreign tourism. 00:00 Koskikatu pedestrian street 2:29 Sampokeskus shopping mall 3:17 (About 3 minutes of copyrighted background music removed from this point forward) 3:51 Lordi-aukio / Lordi's Square (previously Sampo-aukio), renamed in honour of Lordi's victory in the 2006 Eurovision Song Contest 9:33 Walking by the Kemijoki river 18:55 Across "Ounaskosken rautatiesilta" railway bridge 23:50 Walking on the other side of river next to Rovaniemi camping area 32:50 Walking over Jätkänkynttilä bridge 36:38 Back on the centre side of town The approximate route: https://www.google.com/maps/dir/66.50... Shot with GoPro in 4K. https://www.facebook.com/polulla.channel https://www.instagram.com/polullachannel #VirtualTour #VirtualWalk #Finland
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2021 07 10 Kajaani 1
Video Walking around Rovaniemi, July 2021, Finland [4K] - MP4 HD


Tom Discher, 57, a Carson City resident for the past five years, died Sept. 9, 2005, in Carson City. He was born June 4, 1948, in Hayward, Calif., to Donald and Merle Discher.
Before moving to Carson City, he lived in Reno for 15 years.
Mr. Discher was employed with Capitol Cab Co. and took pride in helping his elderly passengers. He was an avid tennis player.
Among his survivors are his father of Stockton, Calif., mother of Walnut Creek, Calif. and sisters Sally Eccles of San Jose, Calif., and Stacy.