These past weeks I have continued to deal with the many aspects of having somebody in my family who was very close to me pass away. On Tuesday I left for New York City to attend the memorial. I had planned, in the two days that I was there, to visit at least one museum show, possibly the Diane Arbus exhibition at the new Met Breuer.
I arrived in New York in plenty of time to attend the memorial for my beloved family member that evening. The celebration of his life, held on a rooftop in Brooklyn, was an outpouring of love and, as such, it was deeply moving.
The following day, after tying up family affairs in Brooklyn, I visited the Brooklyn Museum. I've visited New York many times over the years, but had never been to the Brooklyn Museum. It was particularly rewarding to see Judy Chicago's Dinner Party so beautifully displayed in the Elizabeth A. Sackler Center for Feminist Art at the museum. Years ago, when I was a student in the Feminist Studio Workshop at the Woman's Building, in Los Angeles, I was one of the volunteers who worked on the Dinner Party. I also attended the opening at the San Francisco Museum of Modern Art in the late 70s. The installation languished in storage for years before it found a permanent home at the Brooklyn Museum.


text:
Star of the Sea Books
Thurston, Herbert
The Physical Phenomena of Mysticism
London: Burns Oates, 1952. First edition. Octavo, original navy cloth, navy top edge, original dust jacket. Embossed academic blindstamp, slight tanning to blank flyleaves, minor edge-wear, gentle toning to spine of excellent dust jacket. A bright, fresh copy. Item #572
"THE LUMINOUS PHENOMENA OF MYSTICISM" First edition of the English Jesuit's studies of the manifestations of the supernatural, the collected fruits of a lifetime of research by the noted authority on Spiritualism and the Occult. "When Father Thurston died in 1939 the English Jesuits lost one of the most distinguished members of the Society and Roman Catholics in England their greatest expert in psychical research." So begins Eric Dingwall's review of The Physical Phenomena of Mysticism in the November, 1952 issue of the Journal of the Society for Psychical Research. Dingwall declared this collection to be "the most brilliant and fascinated account of the phenomena of the Saints." Many mystical saints—ranging from Alphonsus Liguori, Catherine of Siena, Mary Magdalen de Pazzi, Philip Neri, and Teresa of Avila to Anne Catherine Emmerich, Gemma Galgani, Beatrice of Granada, Teresa Neumann, Teresa Higginson, Mollie Fancher, and Daniel Home—all appear in these pages.
Herbert Thurston entered the Society of Jesus and was ordained in 1890. Perhaps best-known for his critical editorial efforts to modernize Alban Butler's Lives of the Saints, Father Thurston was also a prolific contributor to the Catholic Encyclopedia and many other periodicals during the 1920s and 30s. Fascinated by the supernatural from a young age, Thurston grew up with a lifelong interest in spiritualism. Dingwall describes Father Thurston as a regular (as early as 1880) in the British Museum Reading Room, evidence of his devotion to research, noting the Jesuit's "wide acquaintance with the different sources" and credits his ability to weigh the "degree of credence to be placed upon them with considerable acumen." Edited, with a brief Preface, by Father Thurston's biographer, J.H. Crehan, S.J., dated "Heythrop, 31st July, 1951." Father Crehan's biography also appeared in 1952 and a companion volume, Ghosts and Poltergeists, was published in 1953. Approbations.
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A major winter storm is threatening to deliver snow, ice and flooding across much of the United States over the next few days.
(CNN) — The winter storm sweeping across the southern United States revealed its power Saturday by dropping 10 inches of snow on Lubbock, Texas — 2 inches more than the city usually gets in a whole year.
Having done its work in Texas, the storm will move east and is expected to pound the Carolinas with heavy snow Sunday, followed by rain, Cabrera said. Sleet and flooding are also possible across the South.
As much as 6 inches of snow might fall in Charlotte, North Carolina, and ice accumulations of a quarter of an inch to half an inch are possible.
Power outages are likely and air travel will be restricted. More than 1,000 Sunday flights have already been canceled at Charlotte Douglas International Airport, according to FlightAware, a flight tracking service.
North Carolina authorities declared a statewide emergency.
Very heavy snow is forecast for the Appalachian Mountains, CNN meteorologist Haley Brink said, with Asheville, North Carolina, and Roanoke, Virginia, predicted to get 12-18 inches. Social media showed snow falling Saturday night in Asheville.
At lower elevations, Raleigh, North Carolina, and Richmond, Virginia, are expected to see 4-6 inches of snow.
Atlanta will probably see rain but not snow, Cabrera said, though northeast Georgia might. The weather could slow air traffic at Hartsfield-Jackson International Airport.
More than 25 million people are under winter weather alerts from Oklahoma through Virginia, and more than 10 million are under a flood threat from the Gulf coast to South Carolina.
The culprit is a moisture-heavy storm that brought downpours and flash flooding along the southern edge of Texas and snow and ice in the north. As that moisture moves eastward, it is colliding with a high pressure system over the Ohio Valley that is funneling cold air into the region.
The flooding and winter precipitation may also affect Georgia. Heavy rain with 1 to 3 inches is projected Saturday, with "rates expected to be high at times, increasing the threat of flooding," the weather service said.
About 1 to 2 inches of snow could fall in the higher elevations of North Georgia, with up to 5 inches on the highest ridges Sunday night into Monday. Possible freezing rain and dusting snow could also reach the I-85 corridor.
Half an inch of ice may coat trees and power lines from Little Rock, Arkansas, to Nashville, Cabrera said.
The National Weather Service predicted 1-3 inches of snow in north and central Arkansas with isolated areas exceeding 4 inches in the northeast.
The southern half of Arkansas faced up 4 to 5 inches of rain, with flash flooding possible. The higher elevations of the Ozark Mountains were expected to see 2 to 6 inches of snow on top of a glaze of ice up to a quarter of an inch.
After the heavy rain in Lubbock, many community activities were disrupted. The city holiday parade was postponed and Texas Tech rescheduled all Saturday final exams until Sunday, CNN affiliate KCBD reported.
Houston saw flooding after a heavy rain storm dumped 4-6 inches on Friday night, with some drivers forced to abandon their cars on major highways, reported CNN affiliate KTRK.


text:
Paul George Snaps Back at Question About Ex-Clippers Star
Heavy on Clippers
By	Bryan Starr
Updated Apr 30, 2021 at 7:55am
Getty	Paul George
Phoenix Suns point guard and surefire Hall of Famer Chris Paul turns 36 next week (May 6), but he probably shouldn't expect a birthday card from Clippers forward Paul George.
Following L.A.'s 109-101 loss to Phoenix Wednesday night — an outcome that gives the 2nd-place Suns some breathing room over the 3rd-place Clippers as the regular season winds to a close — cameras picked up George and Paul conspicuously NOT shaking hands despite clearly crossing paths.
Did both Chris Paul and Paul George refuse to shake each other's hands? Can't tell here, but it definitely feels like no love lost. https://t.co/P6O7wxOsFI
— Farbod Esnaashari (@Farbod_E) April 29, 2021
And just in case anyone thought that maybe the two superstars didn't see each other or that they were just being coronavirus-conscious, George left no room for doubt in his postgame media availability. Asked what makes Paul such a difficult opponent to face, the normally low-key but agreeable George paused for a moment before giving a two-word answer:
Whoa. Naturally, had George responded this way about most other players, a follow-up or two would've been justified albeit awkward, but because he said it about Chris Paul, the context was already clear.
Simply put, a lot of players around the NBA flat out don't like Chris Paul. (Sorry, State Farm.)
Rondo (and Others) Don't Like Paul
For a prime example of another NBA'er who finds Paul less than charming, look no further than George's teammate Rajon Rondo.
On April 8, in only his third game with L.A. following a midseason trade from Atlanta, Rondo and the Clippers squared off against the Suns at the Staples Center in Los Angeles. The game, which L.A. won 113-103, was undoubtedly physical and chippy, resulting in multiple technical fouls and a couple of ejections, and afterward, Rondo, who admitted to deciphering a Suns' play call during a crucial possession, refused to even speak Paul's name.
"No. 3 on the other team yelled it out quickly and loud and I just kind of read it back to my teammates," Rondo told reporters. "It was the same play they called the night before against Utah."
Aside from the impressiveness of preemptively blowing up a play in real-time, Rondo's numerical substitution was a clever reminder that he and Paul were the centerpieces of a notorious flare-up a few years back.
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Back in October of 2018, when Rondo was with the Los Angeles Lakers and Paul the Houston Rockets, Rondo was suspended three games for spitting in Paul's face and landing a punch before players and officials stepped in. The punch, which came after Paul jabbed a finger in Rondo's face, was obvious, but Rondo claimed that he didn't intentionally spit in the first place.
"I had a mouthpiece in my mouth and I exasperated because I was about to tell him to 'Get the (expletive) out of here.' Look at my body language," Rondo told ESPN. "If I spit on you on purpose, I'm going to be ready for a man to swing on me. [I'm not] going to have my hands on my hip and my head look away at someone if I spit on them."
Did Rondo spit on Chris Paul? Was Brandon Ingram justified in shoving James Harden? | SC with SVPRyen Russillo says he enjoyed the brawl between the Los Angeles Lakers and the Houston Rockets at Staples Center. Russillo weighs in on whether Rajon Rondo actually spit on Chris Paul as CP3 claims and backs up Brandon Ingram's decision to shove James Harden. ✔ Subscribe to ESPN on YouTube: es.pn/SUBSCRIBEtoYOUTUBE ✔ Subscribe to ESPN…2018-10-21T14:42:04Z
As far as Rondo was concerned, it was another example of the league wanting to paint Paul as a good guy, despite his reputation amongst the players as an agitator who often resorts to dirty tactics.
"Of course, the NBA went with his side because I got three games and he got two," Rondo told ESPN. "Everyone wants to believe Chris Paul is a good guy. They don't know he's a horrible teammate. They don't know how he treats people. Look at what he did last year when he was in LA — trying to get to the Clippers locker room. They don't want to believe he's capable of taunting and igniting an incident."
Rondo was referring to a bizarre incident from early 2018, when Paul and several other Rocket teammates approached the Clippers locker room with bad intentions following a raucous end to their game. Paul, who spent six years as a Clipper (2012-16), was reportedly intent on teaching his former teammate Blake Griffin a lesson, and though nothing ultimately came of it, the event was emblematic of the way many former teammates perceive Paul.
Shooting guard Nick Young, a teammate of Paul's for 22 games in 2011-12 and a free agent at season's end, said that Paul once taunted him by saying "something like, 'Remember, I'm the key to your next contract.'" And Glen "Big Baby" Davis, who played with both Rondo and Paul in Boston and Los Angeles, respectively, tweeted shortly after the spitting incident that "CP3 is a very bad teammate."
Big Baby chimes in 🍿 pic.twitter.com/v1UG8ZBcp1
Even those seemingly without a gripe against Paul admit that he can often rub teammates the wrong way. Former Clipper JJ Redick said that Paul's style "can grind at you a little bit" though he said it never bothered him. "I always liked it," said Redick.
Playoff Matchup Could Mean Major Fireworks
Though Rondo, of all the Clippers, has the most public beef with Paul, this is by no means George's first run-in with the 11-time All-Star. Back in January, when the Clippers and Suns met for the first of three times this season, George had to be restrained from Paul and Suns guard Devin Booker, with Booker reportedly calling Paul several derogatory names.
And following their previous matchup, the one in which Rondo refused to say Paul's name, George spoke about the Suns' trash-talking, dismissing it essentially as utter nonsense and beneath him and his team.
"I don't know what their chirp was about," said George. "We focused on us. I don't care what they're doing over there. I don't care who they are or what they're doing. I'm locked in. They can do the chirping, I let them have it tonight. I just stayed in my zone, stayed in my place. But again, I don't care what they're doing, we're focused on us over here, we're focused on getting better."
If the Clippers and Suns both survive the first round of the playoffs, there's a good chance they'll meet up in the second round. For two talented teams, each with something major to prove — the Suns that they have crossed the threshold from up-and-comers to contenders, the Clippers that they can finally go the distance — the intensity will be sky high and fireworks will almost certainly fly. But hopefully not any spit.
READ NEXT: Playoff Legend Pegs Clippers as Favorite to 'Dethrone' Lakers
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PG wasn't about to throw out any compliments.


Crisp. Clean. Classic. The Bolle Club Whites 1/4 Zip Long Sleeve top lets you shine in an all-white ensemble that's perfect for the country club's tennis courts. White doesn't have to be boring and this skort is certainly anything but that! This quarter zip is the perfect warmup piece to wear over a Bolle Club Whites Tank and pair with a matching skort or skirt.
Fabric features UV sun protection.
Inclues thumbholes at the sleeves for extra coverage.


text:
Replacement of Karachaevo-Cherkessia's President Highlights Kremlin Crisis in Appointment System
Publication: North Caucasus Weekly Volume: 12 Issue: 5
By: Valery Dzutsati
March 2, 2011 06:39 PM Age: 12 years
On February 28, President Dmitry Medvedev appointed two heads of North Caucasian republics, Karachaevo-Cherkessia and Chechnya. Ramzan Kadyrov was reappointed to rule Chechnya since his first term as head of the republic was about to expire. Karachaevo-Cherkessia received a new leader, 34-year-old Rashid Temrezov, while the previous governor of the territory, Boris Ebzeyev was dismissed from his post before completing his first term, which should have lasted until 2013 (RIA Novosti, February 28).
President Medvedev signed a decree accepting Ebzeyev's resignation on February 26. The decree cited "his own request" as the reason for Ebzeyev's dismissal (www.kremlin.ru, February 26). An anonymous source in the Kremlin added that the Russian leadership was unhappy about the slow socio-economic development of Karachaevo-Cherkessia (RIA Novosti, February 26).
However, an expert from Karachaevo-Cherkesia, Murat Gukemukhov, told the Voice of America that Boris Ebzeyev simply could not control the republic. Reportedly as late as February 24, the then president of Karachaevo-Cherkesia tried to rally the local parliament to support him to avert his removal from the office. Fewer than 30 of 73 deputies of the republican parliament turned up. Gukemukhov asserted that President Ebzeyev lacked influence in Moscow, local connections and the necessary management skills to be in charge of this complex republic. Ebzeyev's key ally in the parliament, Islam Krymshamkhalov, was assassinated in January 2009, which undercut the president's ability to control the local elites (www.voanews.com, February 26).
The newly confirmed head of Karachaevo-Cherkessia, Rashid Temrezov, stated on March 1 that his main goal would be improving the socio-economic situation in the republic and reducing its dependency on Moscow's financial aid (www.kavkaz-uzel.ru, March 1). It must be noted, however, that during Ebzeyev's presidency, Karachaevo-Cherkessia's reliance on centralized budgetary funds was in fact reduced from 71 percent in 2008 to less than 66 percent in 2010 (https://openbudget.karelia.ru/budnord/russian/north-caucasian/karachi-cherkess-republic/resp_cherkesia.htm). So the trend appeared to be positive under the previous leader; indeed, Karachaevo-Cherkessia has been one of the least dependent territories in the North Caucasus on Moscow's financial handouts. Russia's ministry for regional development also indicates average development benchmarks for Karachaevo-Cherkessia. The republic was behind other North Caucasian republics in the housing sphere, which is probably a significant indicator revealing the poverty level in the republic (https://www.minregion.ru/north_caucasian/Karachaevo_cherkess).
Karachaevo-Cherkessia is a small but ethnically complex republic in the northwestern Caucasus, with a population of 400,000. Ethnic Karachays, a Turkic-speaking people who are closely related to the Balkars in neighboring Kabardino-Balkaria, make up 39 percent of the residents. Ethnic Russians comprise 34 percent of the total population, but they are politically inert and declining in numbers because of low birthrates and outmigration. The Cherkess and related Abaza people altogether make up about 19 percent of the population. Turkic-speaking ethnic Nogais, who also live in large numbers in Stavropol region and Dagestan, make up 3 percent of Karachaevo-Cherkessia's population (www.perepis2002.ru, March 1, 2011).
The worst clashes in Karachaevo-Cherkessia occurred in 1999 during the local presidential campaign and in its immediate aftermath. Ethnic Karachays and Cherkess (aka Circassians) rallied each behind their own kin to win the elections. Being a minority, the Cherkess regularly raise the issue of separating from Karachaevo-Cherkessia and have called for the formation of a Circassian republic within Russia. In 2004, the office of the then president, Mustafa Batdyev, was ransacked by crowds of protesters after Batdyev's son-in-law was implicated in killing of several businessmen.
Despite its recent violent past, Karachaevo-Cherkessia last year had the least number of victims of insurgent attacks among government forces in the North Caucasus: just one serviceman was killed (www.memo.ru, February 17). Keeping the republic quiet is one of the main demands and expectations of the republic's population after its leadership was so suddenly changed (www.kavkaz-uzel.ru, March 1). This is going to be a daunting task for the new president of Karachaevo-Cherkessia, who is the youngest appointed leader in the North Caucasus to date and has no experience of running a territory. On February 15, five insurgents were killed by Russian security forces in the border area between Karachaevo-Cherkessia and Stavropol region. Earlier, on February 4, the same group of insurgents attacked a police escort in Karachaevo-Cherkessia and freed one of their comrades-in-arms (www.kavkaz-uzel.ru, February 15).
Boris Ebzeyev's dismissal was evidence of one of the most spectacular failures of the new model for appointing regional governors in the North Caucasus, given that he was the first among Medvedev's regional appointees and was unable to survive even for one full term. The former president of Karachaevo-Cherkessia had an extensive legal background as a professor of law. Ebzeyev was one of the writers of the Russian constitution and served as a judge on Russia's constitutional court from 1991 to 2008. Yet, with all his splendid academic and legal background, he was apparently ill prepared to face challenges on the ground in Karachaevo-Cherkessia.
Ebzeyev's successor Temrezov is said to be close to the previous president of Karachaevo-Cherkessia, Mustafa Batdyev, who was not reappointed by Moscow for a second term in 2008 and was also disliked by many in the republic (www.voanews.com, February 26). Temrezov's most recent post was head of the road maintenance and construction federal agency, Rosavtodor, in Karachaevo-Cherkessia. The agency is notorious for its corrupt practices (www.echo.msk.ru, February 26).
Moscow's attempts at social engineering through the appointment of regional governors in the North Caucasus have proven ill fated so far. Ramzan Kadyrov's ability to control Chechnya is often cited as a success story for Moscow. But, as many observers note, Medvedev's inability to safely remove Kadyrov from office actually attests to Russia's barely disguised profound weakness in the North Caucasus. As Moscow feverishly tries to create complex bureaucratic constructions in place of popular elections for regional governors, the appointment system in the North Caucasus precludes further deterioration of the situation and loss of control over the regional processes.
Government Helpless as Rebels Expand Ope..Next
Is Karachaevo-Cherkessia the Next North ..


text:
SNIDER: To start rebuild, Redskins must find new blood
The Redskins need synchronicity. The NFL can help.
A civil war persists at Redskins Park, fueled by an owner who ignores its downside. But, there's no regrouping from yet another meltdown of the Dan Snyder era without firing president Bruce Allen by season's end.
Snyder's problem is he's not knowledgeable about replacements. He doesn't follow other teams intimately to know which assistant general manager to hire. He clings to Allen out of familiarity.
However, the NFL can recommend a headhunter to vet candidates. A new general manager will hire the next coach, who decides the next quarterback. Get these three pieces aligned and there's a blueprint to rebuilding.
The problem is the Redskins are once more out of sync. By drafting Dwayne Haskins 15th overall last spring, Washington has an incumbent problem. Then again, Haskins doesn't appear near ready. The Redskins need to play him regularly to decide whether he's the 2020 quarterback or use the first-rounder that's a likely top-five pick on a quarterback, left tackle or cornerback given Josh Norman isn't likely to return for his final year at $12.5 million.
It's OK to pick another passer while continuing to develop Haskins. The NFL is all about having two good passers nowadays because of injuries. If Haskins isn't ready, Washington can let its new coach pick his passer.
WATCH: Scott Van Pelt skewers Snyder, Allen
Redskins go with Callahan, but Haskins will still sit
SNIDER: Bruce Allen must be fired today
Who will the Redskins hire to replace Gruden?
Otherwise, we've seen this misalignment go badly. Steve Spurrier arrived in 2002 only to watch Snyder choose quarterback Patrick Ramsey, who the coach didn't want. Mike Shanahan didn't want Jason Campbell, who was traded. Jay Gruden didn't need long to bench Robert Griffin III for Kirk Cousins.
Of course, it doesn't always work. Coach Norv Turner gained Heath Shuler after arriving in 1994 and eventually went for fellow rookie seventh-rounder Gus Frerotte. Shanahan gained Donovan McNabb, who was a bust. But, the best chance for success is common goals among the GM, coach, and quarterback. Otherwise, conflicting agendas lead to firings.
Snyder doesn't like working out of an inner circle, though. That's not uncommon among the rich and famous who don't trust outsiders. Meanwhile, has Allen ever hired someone who wasn't connected to his Oakland-Tampa Bay past?
There's a chance the new GM could be promoted from within via Kyle Smith or Eric Schaffer, both credible team execs who would probably gain less independence by Snyder than an outside hire. The next head coach could be offensive coordinator Kevin O'Connell, a promising young play caller many liken to Los Angeles Rams coach (and former Redskins offensive coordinator) Sean McVay. Again, O'Connell would be given less leeway than an outsider.
Washington needs a new look with new people. The question is whether Snyder is willing to do so.
Rick Snider has covered Washington sports since 1978. Follow him on Twitter: @Snide_Remarks.
Kyle Smith
Eric Schaffer


While not technically making it into the Superfood ranks, coconut water does have some advantages over other sports drinks. It is totally natural and is not loaded with sweeteners, preservatives or coloring. Its celebrity status has come from its low calorie, fresh and pure properties.
While freeze-drying is the most expensive drying process, it does deliver a product of superior quality, and when reconstituted in a glass of water delivers all the goodness, freshness and flavor of a freshly harvested coconut.
Coconut water is the perfect companion during air travel. Pressurized planes are notorious for causing dehydration; and coupled with drinking alcohol, eating too much and sitting for long periods this is a perfect environment to run down your immune system and arrive at your holiday destination sick.
1. Freeze dried Coconut Water with 30% freeze dried Maqui berry powder – the berry which is #1 for antioxidant content. So, now while travelling you can enjoy rehydration and immune support the natural way.
2. Freeze dried Coconut Water with 30% Yum berry powder – the berry which is #1 for proanthocyanin content. OPC's support the strength and integrity of blood vessels, veins, gums and the brain and spinal cord.
Just add a Tablespoon (approx. 10g) of the powder to a glass of water for every 2-3 hours of air travel. In addition, you should drink at least another glass of plain water every hour while flying (and an extra glass of water following every alcoholic drink you consume).
Cabin pressure dehydration, lack of movement and alcohol can all lead to sticky blood – blood which is more likely to clot and cause Deep Vein Thrombosis – a known risk with air travel – so make sure you get up and move regularly and start to hydrate yourself a day or two before a long journey. Your doctor may even recommend taking low-dose aspirin leading up to and during air travel – this also helps to reduce blood clotting but doesn't mean you can forget about the other key things we have mentioned above.
Freeze dried Coconut Water is a great travellers friend. Whether you are travelling in the tropics, hiking, cycling or on a long bus or car journey, freeze dried coconut water can go straight into your pump bottle and keep you healthy and hydrated while you are on the go.
The powder lasts well at room temperature – just make sure you reseal the pouch after each use so the powder does not absorb moisture from the atmosphere. Light, economical, as fresh as the day it was picked and easy to carry, freeze dried coconut water powder is the gold standard for rehydration.


This heirloom is from the 1800's, perfect for dry beans, grows approx 45cm tall with pink flowers and speckled pink and white beans.
Sow in Spring and Summer or all year in warm northern areas.
Sow 25mm directly in final position, seedlings emerge 6-10 days, space 15cm apart.
Dwarf Bean Heirloom Mix 25 seeds This is a mixture of all our bush / dwarf bean types to give you a good range in a single packet. Sowing time - Spring and summer (needs 18+ degrees C) Prefer sunny position, sow 25mm deep, emerge 7-10 days Harvest in approx 50 days after sowing An excellent contribution to the vegetable garden!
CHICKPEA 30 SEEDS / Make your own hummus!


text:
Proudhon
The Libertarian Labyrinth
Encounters with the Anarchist Idea / Tools for an Anarchist Entente
Contr'un
@ Beginnings
Sex Question
Saint-Ravachol
HomeContr'unP.-J. Proudhon, The Celebration of Sunday — III
P.-J. Proudhon, The Celebration of Sunday — III
January 15, 2012 Shawn P. Wilbur Contr'un, translations
THE CELEBRATION OF SUNDAY
[Continued from Part II]
I approach what is perhaps the most difficult part of my subject, because of the pitfall that it seems to cover: moral utility. What is the influence, on the morals of individuals and of society, of the observation of Sunday considered in itself, independent of the force that religion lends to it, and setting aside faith in dogmas and mysteries? Such is, at least, the manner in which I take up the question, and I do not think, I admit, that one could understand it otherwise. It is not a question of launching oneself into the vast field of religious opinions, to demonstrate the utility of public worship by the benefits of religion. All these questions are pointless and even, with regard to truth, trivial. It is not a homily on the effectiveness of Sunday as a source of divine favors that is called for, it is the indication of the relations that can exist between a conspicuous, public ceremony and the affections of the soul. Thus, it is necessary to separate the material from the spiritual, the nominal from the abstract, the human from the revealed, and say that what one practices apart from society, isolated, still preserves some moral utility; for the thought of the founder had to have been that every religious observance has its natural as well as its theological reason.
Another distinction is still necessary. The moral effects of Sunday are either mediate or immediate. By mediate effects, I mean those which rise from the circumstances which accompany the Sunday celebration; such are the relations of family and city, with which I will not concern myself further; and by immediate effects I understand those that Sunday produces by its own special action, independent of every social or domestic influence. This distinction, relatively unimportant in practice, has the advantage of better specifying my point of view, and sparing me repetitions.
"Nature has placed within man the feelings of pleasure and sadness, which force him to avoid the physical objects that seem harmful to him, and to seek those that suit him. The chief work of society will be to create in him a rapid instinct for moral affairs, which, without the tardy aid of reasoning, would lead him to do good and avoid evil. For the individual reason of man, lead astray by his passions, is often only a sophist who pleads their cause, and the authority of the man can always be attacked by his love of self. Now, what produces or replaces that precious instinct, what makes up for the insufficiency of human authority, is the sentiment that nourishes and develops the compulsory exercise of worship; it is this respect mixed with fear that inspires for the moral precepts the full spectacle and majesty of the solemnities which consecrate and celebrate them."[1]
The thought expressed in this passage is ingenious and beautiful; what's more, it is perfectly true. That quick instinct, that second conscience, if I dare put it thus, has been created in the heart of the Israelite by the Sabbath, and Sunday lifts it to a higher degree than it does the soul of the Christian. Moses spared nothing to deeply instill respect for the Sabbath: ablutions, purifications, expiations, abstinences, absolute prohibitions, and strict injunctions. He multiplied, almost to excess, anything that could inspire the idea of the highest sanctity, and carry the veneration almost to the point of terror. On imaginations more impassioned because they are less cultured, the opinion of a more present divinity is all-powerful. The majesty of the sanctuary seems to forbid the approach of crime, and more than once we have seen great culprits, seized by a divine panic, flee frantic and shaking from a refuge where their crimes would no longer find themselves safe. Moses transported that horror of sacrilege from space to time: he rendered certain days inviolable, as he had consecrated certain objects and certain places. And vice, surrounded on all sides by the forces of religion, had no rest, no longer knowing where to hide itself.
But this charm that Moses had cast on the Sabbath, this new sort of scarecrow by which he warded off evil spirits, took all its virtue from a rather vulgar accessory, scarcely worthy of respect or fear: it was, if I dare make use of this withering word, (which is, thank heavens, not from our language,) it was the far niente, doing nothing. A philosopher would not have been aware of it, but Moses seized it.
The ancients, greater observers than we like to believe, perhaps because we don't observe the same things, had remarked very well the effects of solitude on the morals of man. In solitude, the feeling of the infinite touches us, the passions fall silent; reason, clearer and more active, deploys all its strength and gives birth to miracles: character is strengthened and developed, imagination increases, the moral sense responds to the urgings of Divinity. The temples and oracles were placed by preference in remote places, planted thickly with trees, whose shadows invited meditation and contemplation. The wise, returned from the world and the passions, the lovers of the muses and nature, the legislators themselves, as well as the seers and poets, fled, sometimes in agreeable retreats, sometimes in frightening solitude, the indiscreet regard of the profane, who believed them to be in commerce with the gods. Solitude, when it is not the effect of a savage humor or a proud misanthropy, appeared to them the purest image of heavenly beatitude, and the fondest wish of a great soul would have been that all mortals know how to enjoy it and make themselves worthy of it. But if such is truly the highest destiny of man on the earth, in what sense is it sociable? How will its narrow residence suffice for a multitude of anchorites?
If Moses had had the power, he would never have had the thought to transform his farmers into effective hermits; he only wanted to make them men, to accustom them, by reflection, to seek the just and the true in everything. Thus he strove to create around them a solitude which would not destroy the greatest affluence, and which preserved all the prestige of a true isolation: that was the solitude of the Sabbath and the feasts. Constrained, under terrible penalties, to cease their labors for these solemn days, the Israelites submitted to the yoke of an unavoidable meditation; but, incapable by themselves of directing their attention and occupying their thought, they found themselves delivered up to the mercy of circumstances and the first comer: it was there that their teacher awaited them. I have already said what occupations had been assigned by Moses to the Sabbath day. That great and holy man had wanted all the Hebrews, from the children to the elderly, to be able to walk, by his example, with the Lord, and to live in a permanent communication with him. That is demonstrated, indisputably, by a passage in the book of Numbers, where it is related that Moses having chosen seventy men to aid him in the details of government, these men were animated with the same spirit as him and prophesied. And when Joshua came to say: "Master, there are still two men who prophesy in the camp; stop them.—"May it please God," he responded, "that all the people should prophesy!" Let us say, in a slightly more human language, that nothing seemed more desirable to him than to maintain in the intelligence that tempered enthusiasm which produces knowledge of the good, the contemplation of ourselves and of the spectacle of nature.
The last night of the week is passed; the sun begins again its daily course; all the vegetation blooms and salutes the father of the day. Faithful to their instinct, the animals do not stop any more than the plants: the dormouse digs its burrow, the bird builds its nest, the bee collects pollen from the flowers. Nothing that lives suspends its labor: man alone stops for one day. What will he make of his long and drifting thoughts? He will hardly have roused himself from slumber, and already his inactivity will weigh on him: the evening arrives, and the day appears to him to have lasted for two days.
For frivolous spirits, Sunday is a day of unbearable rest, of frightening emptiness: they complain of the ennui which weighs them down. They blame the slowness of these unproductive hours, which they do not know how to spend. If they flee, in polite visits and worldly conversations, from the emptiness of their thoughts, they only add the void of the thoughts of others. From that arise the inventions of debauchery and the monstrous joys of the orgy.—Let those blame only themselves for the numbness that makes them stupid, the inconstancy of heart and understanding that exhausts them, and the dull paralysis that gnaws at them. When its partner lies idle, the spirit only goes more quickly: be careful, if you don't know how to feed its all-consuming activity, that it does not consume itself.
Happy is the man who knows how to shut himself us in the solitude of his heart! There he keeps company with himself; his imagination, his memories, and his reflections respond to him. Let him promenade then along the crowded streets, let him stop in the public squares, let him visit the monuments; or, more happily, let him wander across the fields and meadows, and breathe the air of the forests; it matters little. He meditates, and he dreams. Everywhere his heart, happy or sad, elegant or sublime, belongs to him. It is thus that he judges everything soundly, that his heart is detached, that his conscience is invigorated, that his will is sharpened, and that he feels virtue bound up in his chest. It is thus that he begins with God himself, and that he learns from him, in conversations that none will repeat, what it is to live, and what it is to die. Oh! Then, as all things are reduced to their just value, how little worthy it appears that for their sake we hold onto life, or that for them we would seek death! We ask fearfully what the best remedy would be for the epidemic of suicide which multiplies its victims every day. That remedy, which we have sought everywhere except where it was to be found, was furnished by homeopathy. Make life contemptible, and we will no longer want to leave it; we only esteem it if we find it to be a burden. The stoic who, in prosperity, knows how to sacrifice his existence, also knows how to bear pain; he even denies that it is an evil. The disciple of Epicurus, lazily in love with life, curses it as soon as it no longer offers him pleasure. It is among the tombs, a skull in his hand, that he must preach against suicide.
What heroic self-sacrifices and heart-rending sacrifices were consummated internally in these inexpressible monologues of the holy days! What high thoughts, magnificent conceptions, descend into the soul of the philosopher and the poet! What generous resolutions were made! Hercules, at the end of adolescence, offered a sacrifice to Minerva. Standing before the altar, after having made some libations and singing hymns to the goddess, he waited, immobile and silent, until the flame had consumed the offering. Suddenly he saw two women appear, two immortals, Pleasure and Virtue, who, displaying their charms, demanded his homage. Pleasure flaunted all her seductions. Virtue offered labors and perils with an incorruptible glory. The young hero chose Virtue. Woe unto those who do not have the same vision! Great woe unto those who do not choose as did the son of Jupiter!
According to the preceding observations, the same cause suffices to explain both the energy that the moral sense can acquire, and the excesses where libertinism is plunged as a result of the observation of Sunday: that cause is the increase of activity given to the mind by the rest of the body. It is up to those charged with the protection of the customs, the education of the young and the direction of the public amusements, to turn to the advantage of morals an institution which, after religion itself, is the most precious remainder that we have preserved of the ancient wisdom, and the excellence of which is demonstrated by the very debaucheries for which it furnishes the occasion.
Among the upper classes, Sunday is no longer recognized; the days of the week all resemble one another. For those only occupied with speculations, intrigues and pleasures, it hardly matters what day it is; the intervals marked for rest no longer mean anything. The people sometimes holds back its passions for a week; the vices of the great are not deferred. Is the impiousness of the rich, established in their habits, incurable? The people, more faithful to its traditions and less open to attack in their character, are always under the hand of religion. I would even dare to suggest that with respect to Sunday the last glimmer of poetic fire is extinguished in the souls of our rhymers. It has been said: without religion, no poetry. It is necessary to add: without worship and without holidays, no religion. But since poetry, becoming rationalist, has raised the veils that covered the Christian myths, since it has left the allegories and symbols to raise itself up to the absolute, it is true to say that it has killed its foster-mother, and with the same blow committed suicide. Among the people, on the contrary, the lack of devotion does not exclude every religious idea. They can detest the priest, but never hate religion. They blaspheme against the dogmas and mysteries, and they prays at the graves and kneel at the blessings. And when faith no longer resonates for them, the poetry of Sunday still thrills.
Blonde Marie was loved by the young Maxime; Marie was a simple working woman, and in the naïveté of a first love; Maxime, a hard-working artisan, combined reason with youth. Nature seemed to have predestined these lovers to happiness, by blessing both with simplicity and modesty. Diligent at work every day of the week, Maxime tried hard to increase his savings; Marie braided in silence her wedding crown. They only saw each other on Sundays; but it was beautiful, it was solemn for them, this day when it was sung in heaven: Love is stronger than death! It spread the influence of religion and innocence over their mutual affection! True lovers are never sacrilegious: full of a loving respect, what would the young man have dared? What would the girl have allowed, beautiful in her modesty and the joy of the Sabbath? Alone with their love, they were under the protection of God. The revolution of July came suddenly to destroy such bliss. Maxime was told to provide for himself: no more work, no more joy. He resolved to move away for awhile and make for the capital. On the eve of his departure, a Sunday evening, he took Marie's hand, and, without speaking to her, led her to the church.—"If I remain faithful, how shall I find you, Marie?"—"Do as you say, and you may count on my faithfulness."— "Will you promise me before God?" She promised. They went out; the night was fine; Maxime, according to the custom of lovers who part ways, showed Marie the polar star and taught her to recognize its position.—"Your eyes will no longer meet mine," he said to her; "but every Sunday, at the same hour, I will look in that direction. Do the same, so that at a single instant, as our hearts are united, our thoughts will merge. That is all that I ask, until I see you again." He left. Paris did not always give him work; his days of unemployment became fatal to him. At the instigations of some friends, Maxime joined a republican society. An invincible melancholy took hold of his soul and altered his character. "Do you know," he wrote to Marie, "why you are so poor, when so many shameless sorts live in luxury? Why I can't marry you, when so many men throw themselves into debauchery?… Do you know why I sometimes work on Sunday, when others play or indulge their boredom all week long?… God has allowed the good to be the first to suffer from the vices of the wicked, to teach them that it is up to them to prune society and make virtue flower again. If the just were never to complain, the wicked would never mend their ways; the contagion would always spread, and the world, soon all infected, would perish… Pray to God for me, Marie; that is all that a weak woman can do. But there are a million young men, virtuous and strong, all ready to rise up, who have sworn to save the nation… We will triumph or we will know how to die." Maxime was killed behind a barricade during the June days. From that time, his lover wore mourning. Orphaned from a young age and no longer having a mother, she attached herself to the aged mother of her fiancé. Her days were passed in labor and in the cares of a tender devotion. Every Sunday she was seen, in the dark chapel where she promised Maxime her heart and faith, assisting in the divine office. It is there that her heart, calm and resigned, was strengthened and purified in an ineffable love. And at night, after her prayers, heart full of the last words of Maxime,—until I see you again,— the sad Marie gazed sighing at the polar star.
[1] Session of the National Convention for 18 Floréal, Year II, Carnot presiding. Report of Robespierre in the name of the Committee of Public Safety.
[Working translation by Shawn P. Wilbur]
[Continued in Part IV]
About Shawn P. Wilbur	2309 Articles
Independent scholar, translator and archivist.
The Celebration continues
P.-J. Proudhon, The Celebration of Sunday — IV
Proudhon Library
On the Absolute (1851)
January 14, 2016 Shawn P. Wilbur Proudhon Library, Working Translations
P.-J. Proudhon, Carnets, Vol. 4 (Carnet no. 9, 112-115): 287-290 [112] July 26 [1851]. — On the Absolute. — All the religions, all the old metaphysics, are based on the notion of the absolute, on […]
anarchist mutualism
1848 origins of "agro-industrial federation"
December 5, 2007 Shawn P. Wilbur anarchist mutualism, Contr'un, Contr'un Revisited
Mutualism is Approximate (from LeftLiberty 2)
September 11, 2009 Shawn P. Wilbur Anarchism, mutualism
Mutualism: The Anarchism of Approximations[continued from Part II]__________ Mutualism is approximate. Mutualism values justice, in the form of reciprocity. Mutualism is dialectical. (Or "trialectical." Or serial.) Mutualism is individualism and socialism—or it is neither. Mutualism […]
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The Anarchist Library
Anarchy 101 Q&A


• For quantitative determination of fumarase enzyme activity.
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• FUMARASE (or fumarate hydratase) (EC 4.2.1.2) is an enzyme that catalyzes the reversible hydration/dehydration reaction of fumarate to malate. Fumarase exists in two isoforms: a cytosolic and mitochondrial form. In the citric acid cycle, it facilitates a transition step in the production of energy in the form of NADH. Fumarase deficiency in humans results in early brain development problems and is characterized by poor feeding, hypotonia, failure to thrive, etc. BioAssay Systems? non-radioactive, colorimetric fumarase assay is based on the reduction of the tetrazolium salt MTT in a NADH-coupled enzymatic reaction to a reduced form of MTT which exhibits an absorption maximum at 565 nm. The increase in absorbance at 565 nm is proportional to the enzyme activity.


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We only offer mobile hardwood floor showroom service in Victoria. All you have to do is make a call to us and we will be on your doors in no time. Not only we will show you the samples but also give you suggestions about what option would be suitable for your house. You can get lots of options and samples to choose from and we firmly hope that you will get your desired product.
Another great thing about the mobile hardwood floor showroom that, we will have the chance to see your house in person and that will make it very easy for us to suggest to you the best possible flooring. Our expert and professional flooring employers will be there and they can suggest you and help you to choose the best flooring option and material possible according to your budget.
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More links for "PB22-J 128GB 2.5" SATA-II Solid State Hard Drive (MMCRE28G5MXP-0VB)"
Bought this to upgrade my MacBook Pro hard disk. This thing is crazily fast.
I got one of these last week to put my new install of Windows 7 on. Very impressed, so much so I'm waiting on my second one to arrive. Everything now happens instantly. It's a bit like going from a dial-up connection to broadband, (for those that are old enough to remember dial-up), until you do you don't realise how good the interweb is.
Thought i would put a few words down on a review to put those people whom are hesitant as i was about the purchase of a solid state..
Its not very big as in Gbs but is more than ample to run your operating system, mine was Windows 7 for those who are interested, I7 920 6Gb crucail memory and a nice ATI 5870 graphics card..
Put it this way, ive got everything i need installed, games aswell and i still have 90 gigs spare..
Easy to install no need for any hassle plug it into the sata port and power it up and away you go..
i purchased a 64gb samsung ssd from overclockers a while back and it was awesome.
.... this time around it was no contest on the one to choose, absolute quality.
combine that with the free next day delivery and your on a winner!
I bought this SSD hard drive to research if it would improve start up and application speeds, well all I can say is WOW. This item significantly improves every aspect and usability of my MacBook (sorry PC users) which runs with 2.5ghz processor and 4GB RAM. Everything works literally instantly. What more can you ask for. Maybe I should have bought the 2556GB!!!
win xp pro all service packs installed startup from pressing the on button to usable desktop 46 seconds.
Not big, but as a boot/applications drive...worth every penny.
I have been engineering PCs for over 15 years and I have never seen any drive before with such a shattering performance. Windows 7 RC installed in 12 mins. Windows boots up much faster than my 10,000 rpm veloraptor Applications eg Word 2007 etc appear on screen instantly.


for the wonderful comments that were left on the last post in regards to the kitchen.
And all the past comments.
I read them all and it always brings a bit of warmth to my heart.
Thank you too, non-commenting visitors.
I love having you too!
There once was a wall and a door where this counter sits in the forefront of this photo.
Removing the door and wall was one of the best things we ever did.
items as decor we didn't feel it too much.
We love the open bright feel to it!
Our home has been decorated on a shoestring.
or the less expensive (lower end ;-) ) IKEA items.
Once again, I have to say , I love IKEA!
including melamine dinnerware from Costco.
Details the NVO added to the built in.
A clock of crocheted roses, of course.
The crocheted rose made from this pattern.
How about that bright blue paint above the fireplace?
A hand crocheted tablecloth from Norway.
Made by mother's oldest sister, Betsy.
through the fireplace?...I wonder what she's been up to?
I spy some pale pink yarn on the chair she is sitting on, as well.
I really like your home. All the white surfaces and the bright colors.
Your dining room looks stunning! I hope you enjoy lots of lovely meals with your family there.. HAve a lovely day! GAia.
Your dining room is so beautiful !! :) Do you eat on that white crocheted table top?
Your house is so bright and cheerful. That tablecloth is gorgeous.
Your kitchen and dining room are gorgeous Astri. I'm jealous.
This is a great post. Your kitchen and dining area are just beautiful. I really like the deck off of the kitchen in your previous post. The fact that you achieved this look in a thrifty way makes it all the better.


Is this the year that viral marketing jumps the shark? Viral hits are organic, they just happen, rising out of no where to take the Internet by storm. What is painfully clear this year is either how hard it is to do viral marketing or how bad the studios are at it.
This season's spate of "viral advertising" has had the exact opposite effect on me then it was intended to have. Take Indiana Jones and the Dark Knight as two examples of all that is wrong. I have seen many articles around the net about the attempts from the Dark Knight marketeers to get a viral campaign up and running, but I have never seen any of these items in the wild.
When the only time your viral video gets play is when bloggers are trying to explain what you are trying to do, then your viral videos have failed.
Then there is Indiana Jones and the Kingdom of the Crystal Skull, which has to be the most botched hype machine ever. The sheer amount of over promising and under delivering that these guys have down has done the unthinkable: It has cooled my interest in Indiana Jones, leading me to skip most articles I see in my feeds because I am almost certain it will be just another picture of a hat on a box or another cobweb picture. The videos have even been dull. I an tired of getting excited about the newest tidbit they announce only to say, "That's it?"
The one bright spot in the malaise of botched viral marketing is Hellboy 2: The Golden Army. When I saw the comics I thought they were alright, the first flick was alright, but nothing that really excited me. The slow drip drop of information about Hellboy 2 turned my head.
At every turn, they have under promised and over performed on each and every item they brought out. My anticipation has grown to the point where I have even started reappraising the first film.
What these studios need to learn is that if you promise me the most amazing picture ever and it is nothing but a hat on a box, it will have demoralizing effect on the people that want to be excited about what you are doing. When you put out a new trailer, make sure it has new footage in it.
More important than any of that, follow Scotty's rule, always under sale what you have so the word of mouth will rise up to proclaim the glory of content. Oh, yeah, and make the content itself worthy of praise.
Older PostLego Indiana Jones Movie?


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Purpose: To compare clinical outcomes of metastatic head and neck cancer patients treated in phase I clinical trials with clinical outcomes of those patients who had their last Food and Drug Administration (FDA)–approved therapy in the setting of metastatic disease.
Experimental Design: We retrospectively reviewed the outcomes of 61 consecutive patients with head and neck tumors treated in 36 phase I trials at The University of Texas M.D. Anderson Cancer Center between July 2004 and September 2009.
Results: The most common histology was head and neck squamous cell carcinoma (62%). Median age was 55 years (range, 26-80). Eastern Cooperative Oncology Group performance status was 0 to 1 for 95% of patients. Fifty-nine patients had received FDA-approved drugs as the backbone of their last systemic therapy before inclusion in phase I trials (median, 2 systemic therapies). Progression-free survival (PFS) on phase I trials was not inferior to PFS on their last FDA-approved therapies (12 versus 10.7 weeks, log-rank P = 0.87). Fifty-three patients were evaluable for response by Response Evaluation Criteria in Solid Tumors criteria. Four (7%) had partial responses and 16 (26%) had stable disease for ≥4 months. In univariate analysis, number of metastatic sites, lactate dehydrogenase (LDH) levels at baseline, and Royal Marsden Hospital prognosis scores were significant predictors of survival. Only LDH was significant in multivariate analysis (hazard ratio, 6.35; P ≤ 0.0001).
Conclusions: For patients with heavily pretreated advanced head and neck tumors, PFS on phase I trials is not inferior to PFS with their last FDA-approved therapy. The only significant predictor of survival in the multivariate analysis was baseline LDH. Clin Cancer Res; 16(15); 4031–7. ©2010 AACR.
Phase I trials were traditionally considered dose-finding studies and patients enrolled in them were rarely expected to derive benefit. This concept is quickly evolving as identification of druggable targets [EML4-ALK and poly(ADP-ribose) polymerase] and therapies directed to these targets have resulted in significant tumor responses in patients treated with them. This success will likely increase the numbers of patients with refractory tumors referred for evaluation in phase I trials. Here, we show that the clinical outcomes in phase I trials were not inferior to outcomes on Food and Drug Administration–approved therapies for patients with advanced head and neck cancers, and we expect that this will increase enrollment of these patients in phase I clinical trials.
The goals of phase I clinical trials are to identify the maximum tolerated dose of investigational drugs for future phase II studies and to define their safety profiles and pharmacokinetic properties. Critics cite the lack of benefit for patients enrolled in them (1, 2). Studies show that as many as 20% of patients enrolled in phase I trials die within 90 days of study entry, although most of these deaths are due to progressive disease, whereas drug-related mortality is <0.5% (3–5). Clinical benefit from these trials is likely to increase when patient selection is refined so that patients with specific biomarkers are fitted to trials with therapies aimed at those targets. Poor performance status is cited by others as one of the reasons for lack of benefit of these trials (6). In this regard, a prospective study has validated the Royal Marsden Hospital (RMH) prognosis score for patient selection in an attempt to improve this process (7). Other critics have pointed to the culpability of low doses of the agents used for treatment in the lack of efficacy of phase I trials. However, we and others recently showed that patients on low doses do not fare worse than those enrolled in high-dose cohorts (8, 9). Another focus to improve patient selection has been to identify the optimal biological dose of a given therapy for target modulation rather than maximum tolerated dose as an end point with the goal of improving clinical outcome (10).
Our study retrospectively reviewed patients with head and neck tumors treated in the Phase I Clinic at The University of Texas M.D. Anderson Cancer Center. We compared clinical outcome in these trials with that achieved using previous standard Food and Drug Administration (FDA)–approved therapies, and we tested the predictive value of the RMH prognosis score in that context.
We retrospectively reviewed clinical outcomes of 61 consecutive patients with head and neck cancers that were treated in the Phase I Clinic at M.D. Anderson from July 2004 to September 2009. Data were collected from all transcribed notes and radiology reports in the electronic database of these patients. Patient records were reviewed for history, laboratory, and clinical findings at the time of presentation in the Phase I Clinical Trials Program, treatment, and clinical outcomes. Pathology was reviewed by an M.D. Anderson pathologist in all cases. Regimens varied over time and according to protocol availability during the time the patients were seen.
All patients had progressed on systemic therapy for metastatic disease. We collected baseline characteristics that included age, gender, tumor histology, Eastern Cooperative Oncology Group (ECOG) performance status, number of prior systemic therapies for metastatic disease, number of metastatic sites and location of metastatic disease, hemoglobin (g/dL), lactate dehydrogenase (LDH; IU/L), platelets (K/μL), albumin (g/L), progression-free survival (PFS) while on last FDA-approved treatment before inclusion in phase I trial, date of initiation and progression to phase I therapy, best response to this therapy based on Response Evaluation Criteria in Solid Tumors (RECIST) criteria, and date of death or date lost to follow-up. All studies were done in accordance with M.D. Anderson Institutional Review Board guidelines.
Patient characteristics were summarized using median (range) for continuous variables and frequency (percentage) for categorical variables. To test the RMH prognostic score, we classified patients according to these three variables: LDH normal (0) versus LDH >ULN (upper limit of normal; +1), albumin >3.5g/dL (0) versus albumin <3.5g/dL (+1), and number of metastatic sites of disease ≤2 (0) versus >2 (+1; ref. 7). Patients were subclassified into good (RMH score 0-1) or poor-prognosis groups (RMH score 2-3) after summing the value for each variable. The probabilities of overall survival (OS) and PFS were estimated using the method of Kaplan and Meier (11). OS and PFS were defined as date from start of therapy (last FDA-approved therapy or initial phase I trial) until date of death or progression, respectively. Patients who were alive or free from disease progression at the time this analysis was conducted were censored on that date. Log-rank test was used to compare OS or PFS among subgroups of patients (12). Univariate and multivariate Cox proportional hazards models were fit to assess the association between patient characteristics and clinical outcomes (13). A P value of <0.05 was considered significant for the purpose of all statistical analyses. All statistical analyses were conducted in SAS version 9.1 (SAS Institute, Inc.) and SPSS (version 17.0; SPSS).
A total of 61 patients with head and neck cancers who participated in an M.D. Anderson phase I clinical trial were included in this retrospective review. There were 51 men (84%). The most common histology was head and neck squamous cell carcinoma (HNSCC; n = 38, 62%), followed by adenocystic carcinoma (ACC; n = 12, 20%) and other histologies (n = 11, 18%) including acinic carcinoma, adenocarcinoma, myoepithelial gland carcinoma, pleomorphic adenoma, ductal adenocarcinoma, and mucoepidermoid carcinoma. The median age was 55 years (range, 26-80 years). The baseline characteristics of these patients are summarized in Table 1.
Of the 61 patients, 11 were included in phase I trials combining classic cytotoxics with targeted agents, 7 were included in trials with multityrosine kinase inhibitors, 6 were in phase I trials with mammalian target of rapamycin (mTOR) inhibitors, 6 were in trials with microtubule inhibitors, and 6 patients were included in trials with proteasome inhibitors. Overall, 28 patients (47%) were treated with a first-in-human drug. The phase I treatments of these 36 patients and the remaining 25 patients are summarized in Table 2.
Among the 61 patients included in the analysis, 59 patients had received treatment based on FDA-approved drugs as their last therapy for metastatic disease before enrollment in phase I trials. Among these 59 patients, 34 (58%) had died at the time of analysis. The 90-day mortality rate was 21% and treatment-related mortality rate was 1.7% (1 of 59 patients). After a median follow-up of 50 weeks (range, 2.4-203 weeks), the median OS for the entire population was 30.8 weeks [95% confidence interval (CI), 14-47.6]. The median survival for patients with HNSCC was 27 weeks (95% CI, 18.6-45.4 weeks), and for patients with ACC, it was 93.1 weeks (95% CI, 42.8-203.0 weeks). Fifty-three patients were evaluable for response per RECIST criteria (Fig. 1). The remaining 6 patients were not evaluable because of suicide (n = 1), off study due to infection and declining ECOG performance status before restaging (n = 3), no measurable disease (n = 1), and new-onset pleural effusion (n = 1). Four patients (7%) had partial responses and 34 (58%) had stable disease. Sixteen patients (26%) had stable disease for >4 months.
RECIST response in 53 evaluable patients.
We conducted univariate analysis to examine the effect on survival of variables including number of prior chemotherapies for metastatic disease, number of metastatic sites of disease, LDH baseline levels, and RMH prognostic score. The number of metastatic sites (1-2 versus ≥3), LDH levels (<ULN versus ≥ULN), and RMH prognostic score (good versus poor) were significant predictors of survival in the univariate analyses. Median OS in patients with ≤2 sites of metastatic disease was 69.7 weeks (95% CI, 27.0-203.0 weeks) versus 25.7 weeks (95% CI, 12.0-51.7; P = 0.03, log-rank test) in those with 3 or more sites of metastatic disease. Patients whose LDH levels were within normal limits (≤618 units/L) had a median OS of 61.7 weeks (95% CI, 29.7-203 weeks), whereas OS for patients with LDH above the ULN was 12 weeks (95% CI, 6.4-22.6 weeks; P = 0.0001, log-rank test). Patients with a good RMH prognosis score also had a longer survival in the univariate analyses (median, 51.7 weeks versus 9.6 weeks between good and poor RMH scores; P < 0.0001). Next, we analyzed whether increasing values of RMH prognostic score predicted a shorter survival. Twenty-four patients had a score of 0, 22 patients had a score of 1, 12 patients had a score of 2, and only 1 patient had a score of 3. Median OS was gradually longer in patients with lower RMH prognosis score, and this was statistically significant [score 0; median OS, 93.1 weeks (95% CI, 29.3-203 weeks); score, 1; median OS, 38.4 weeks (95% CI, 22.6-61.7 weeks); score, 2 or 3; median OS, 9.6 weeks (95% CI, 6.4-21.7 weeks); P < 0.0001, log-rank test; Fig. 2].
Univariate survival analysis based on RMH prognostic score. Patients with good RMH prognosis score (defined by lower values of this score) had longer survival.
In the multivariate analysis, LDH level at baseline [hazard ratio (HR), 6.35 for elevated versus normal LDH] was the only significant predictor of survival (P ≤ 0.0001).
To test whether the clinical outcomes of patients with metastatic head and neck tumors enrolled on phase I trials were inferior to their clinical outcomes with the last therapy they received based on FDA-approved drugs, we conducted a log-rank analysis that compared PFS in both settings. We found that PFS while on phase I treatment was not inferior to PFS with the last FDA-approved drug (median PFS, 12 versus 10.7 weeks; log-rank P = 0.87; Fig. 3). We conducted the same type of analysis in the subset of patients with HNSCC and similarly found that for these specific population of patients, PFS while on phase I treatment was not inferior to PFS with the last FDA-approved drug (median PFS, 9.7 versus 9.3; log-rank P = 0.43; Supplementary Fig. S1). Therefore, for patients with metastatic head and neck cancers that have progressed after two lines of systemic therapy for metastatic disease, referral for evaluation of eligibility for phase I trials might be considered.
The median PFS in phase I trials was not inferior to the median PFS on the last FDA-approved therapy.
Next, we conducted survival analysis to examine whether RECIST response to phase I trials may predict survival of these patients. Patients with ACCs are frequently characterized by long periods of stable disease. To avoid confounding our results by including this subset of patients, we restricted the analysis to patients with HNSCCs. Of the 38 patients with HNSCCs, 36 had undergone restaging by RECIST criteria as previously explicated. We found that patients with stable disease or partial response per RECIST criteria had an increased median OS [stable disease or partial response: median OS, 44.42 weeks (95% CI, 26.0-62.8 weeks); progressive disease: median OS, 15.42 weeks (95% CI, 5.98-24.87 weeks); P = 0.003, log-rank test; Fig. 4].
Kaplan-Meier analysis based on RECIST response to phase I therapy. Patients with partial response (PR) or stable disease (SD) by RECIST criteria had a longer median OS compared with those who had progressive disease (PD) as their best response to phase I treatment.
Whether or not there is clinical benefit for patients included in phase I trials continues to be a concern for many physicians, thus limiting referrals to and recruitment for such trials (15). Here, we show that the clinical outcomes of patients with advanced head and neck tumors that progressed on standard FDA-approved therapies were not inferior to the outcomes of the same patients on their last FDA-approved therapy. The median number of systemic therapies for metastatic disease that these patients had received before inclusion in phase I trials was two. In the absence of specific biomarkers of response, there was no difference for patients with refractory metastatic head and neck tumors being treated with standard versus experimental drugs.
The explosion of new technologies has led to the identification of unique genetic features in many tumor types (16, 17). A plethora of targeted therapies have entered clinical trials, although matching patients with targeted therapies is complicated by the heterogeneity of various cancers. The genetic portrait of different tumor types has recently been elucidated. The finding that each cancer, on average, harbors >60 different mutations shows the complexity of this disease. There is a need to separate "mountains from hills" and identify driver as opposed to passenger mutations (18, 19). This would offer a myriad of therapeutic opportunities, possibly even in the setting of phase I trials (20). As an example of this targeted approach, a phase I trial with a B-Raf inhibitor showed a striking response rate of 60% in a subset of patients with metastatic melanoma, a disease for which no treatment had significantly increased survival (21). A similar strategy has proven to be successful in the treatment of patients with non–small cell lung cancer and ALK4 mutations (22). Our group recently presented data showing high response rates in patients with PIK3CA mutations enrolled on trials with phosphatidylinositol 3-kinase/Akt/mTOR inhibitors (23).
The phase I group at RMH recently developed a score that can be used to predict survival in patients with advanced cancer using baseline clinical and laboratory parameters including albumin, LDH, and number of metastatic sites of disease (7). In this study, we tested the predictive value of the RMH score in our patients. Although we found in univariate analyses that survival was longer for patients who had good RMH prognosis scores and that increasing values of RMH score gradually predicted for poorer survival, we were not able to validate this score in multivariate analyses. However, the relatively small number of patients in our study precludes carrying out a robust analysis. Our findings in multivariate analysis showed that the LDH value at baseline was the only significant predictor of survival for these patients.
In summary, the clinical outcomes for patients with head and neck tumors are not inferior to their outcomes with last standard FDA-approved treatment in a selected group of individuals with good performance status. The rate of stable disease for ≥4 months plus partial response was 33% in these individuals. Patients who achieved stable disease or a partial response had a superior OS to those with progressive disease. However, without a randomized study, it is unclear whether response influences survival or simply if responders were a group of patients who had better prognosis.
Future validation of prognostic scores to assist physicians in better selecting specific subgroups of patients who can benefit from novel therapies as well as the identification of rational therapeutic targets to target in the setting of phase I trials may further affect the outcomes of these patients.
Grant Support: Ignacio Garrido-Laguna is a fundscion caja Madrid fellow.
Revision received May 6, 2010.
. 90-Days mortality rate in patients treated within the context of a phase-I trial: how should we identify patients who should not go on trial? Eur J Cancer 2008;44:1536–40.
. Comparison of prognostic factors in patients in phase I trials of cytotoxic drugs vs new noncytotoxic agents. Br J Cancer 2003;89:1166–71.
. Prospective validation of a prognostic score to improve patient selection for oncology phase I trials. J Clin Oncol 2009;27:2692–6.
. Phase I oncology studies: evidence that in the era of targeted therapies patients on lower doses do not fare worse. Clin Cancer Res 2010;16:1289–97.
. Phase II trial of pharmacodynamically (PDally)-guided optimal biologic dose titration (OBDT) of sorafenib (S) in combination with metronomic cyclophosphamide (mC) in advanced neuroendocrine tumors (aNET). J Clin Oncol 2009;27:1.
. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 1966;50:163–70.
. Regression models and life tables (with discussion). JR Stat Soc 1972;B 34:187–220.
National Comprehensive Cancer Network. Clinical practice guidelines in oncology—v.1.2010. Head and Neck Cancers. Fort Washington (PA): National Comprehensive Cancer Network; 2010.
. Identification of factors limiting patient recruitment into phase I trials: a study from the Royal Marsden Hospital. Eur J Cancer 2008;44:978–82.
. Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 2001;344:1052–6.
. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009;361:123–34.
. Phase I study of PLX4032: proof of concept for V600E BRAF mutation as a therapeutic target in human cancer. J Clin Oncol 2009;27:15s.
. Clinical activity observed in a phase I dose escalation trial of an oral c-met and ALK inhibitor, PF-02341066. J Clin Oncol 2009;27:15s.
. PIK3CA mutations in patients with advanced cancers treated in phase I clinical trials. 2009 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference.


M. Tucker is metro-NY's largest foodservice distributor. As part of Singer Equipment Company, we are one of the six largest distributors of wholesale restaurant supplies and equipment in the country. M.Tucker is headquartered in a 140,000-square-foot office and distribution center in Paterson, NJ – just minutes from Manhattan. We maintain a multi-million dollar inventory of equipment as well as tabletop, kitchen, disposables and janitorial supplies — 12,000+ items are available for next-day delivery. Tucker's fleet of trucks provides delivery services to 2,000+ facilities per week throughout the greater Metropolitan area. An additional 18 Singer Equipment trucks service the greater PA, DE and MD area daily.
We are known for our exceptional kitchen design and installation services. Each year, we design and complete over 200 foodservice facilities across the country, including independent regional operations and national chains. In addition to our Metro-New York presence, we also maintain a strong presence in the Southeastern market with our Miramar, Florida office. Our Miramar, FL team services Florida, Texas, the Caribbean, South America and more.
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The M. Tucker Business Development team poses with Chef Rick Bayless at the NRA Show in Chicago, 2017.
Morgan Tucker with Celebrity Pastry Chef Johnny Iuzzini, at Aspen Food & Wine, 2017.


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text:
written by Artomity Magazine
Food historian Octavia Fox talks about three of her favourite pieces in her collection.
Antonio Casadei was an Italian artist working in Hong Kong during the 60s and 70s. His name is now little known but you would have walked past his work on numerous occasions: the ceramic screens in Statue Square are his, as are the back-lit glass wall in the lobby of the St George's Building and the public sculptures in Mei Foo Sun Chuen. I think he was a great ceramicist and he must have had a substantial kiln somewhere in Hong Kong to produce works like the chunky bas reliefs which once graced the lobbies of the Prince's Building. I have two of his paintings, which my father bought when Casadei was selling art door to door – most probably on his arrival in 1962. These paintings must have been produced in Italy before his arrival but they are, for me, very much a part of that era in Hong Kong.
Antonio Casadei, Mixed media on paper, 1962. Courtesy the artist and Octavia Fox.
Eizō Katō was a Japanese landscape artist who worked in both Hong Kong and Japan. I think his day scenes are nothing special, wispy and hesitant in line and colour, but he painted a series of night scenes of the harbour and the West Lamma Channel which seem to be by a completely different calibre of artist. In these paintings boat lights and the distant buildings of Hong Kong are picked out in gold against a cobalt blue Peak and a moody obsidian grey sky. They capture the harbour as I remember it as a child, when you could sail after work from Queen's Pier to Tseung Kwan O (Junk Bay) for a swim and then come home after dinner at Lei Yue Mun. It is difficult to gauge when these were painted but given his age (born 1906), the war years and the lack of advertising signs on the buildings, I would say 30s. There is a beautiful large work of this type in the Hong Kong Maritime Museum.
Views of Hong Kong at Twilight by Eizo Kato, Watercolour heightened with gold paint,
14 x 31cm. Courtesy the artist and Octavia Fox.
Arthur Hacker, artist, author and historian, would be known to any member of the Foreign Correspondents' Club, where a model of his iconic anti-litter character Lap Sap Chung is proudly displayed. Hacker studied at the Royal College of Art in the 60s, was a contemporary of David Hockney, RB Kitaj and Patrick Caulfield, and came to Hong Kong in the early 70s to work for the Information Services Department. During the 70s and 80s his work was all over Hong Kong: on stamps, on posters and in the many books he produced on Hong Kong iconography. His work can be seen in Hacker's Hong Kong, a book of his drawings which is an interesting historical document: people playing cricket under the Mao-emblazoned Bank of China Building, bar girls and US servicemen in Wan Chai during the Vietnam War, miniskirts and flared trousers; his drawings always told a story in the tradition of 18th-century caricaturists but as you get drawn into each scene, it's easy to miss the brilliance of his draughtsmanship. His drawings are spare; with a few lines he is able to define a person's volume or a martini glass. Yet these drawings are covered in a latticework of baroque curlicues which form beehive hairdos, waves lapping against junks or steam rising from a dim sum basket – somehow these two different parts to his style always form a harmonious whole.
Arthur Hacker, Pen and ink drawing, 61 x 45 cm, 1973.
Courtesy the artist and Octavia Fox.
Filed under: Collector
Tagged with: Antonio Casadei, Arthur Hacker, Eizō Katō, Octavia Fox
by Artomity Magazine
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A new documentary film, FOOD CHAINS is coming soon to a theater near you, beginning NOVEMBER 21st If you are interested in farm workers and the food industry, this is an important film to see. Its executive producers, Eric Schlosser, Eva Longoria and Abigail Disney, are emphasizing its importance in galvanizing American's to transform the industry.
SYNOPSIS: Food Chains is a ground-breaking documentary film that exposes the abuses rampant in farm labor and reveals the forces behind that exploitation through the narrative of the Coalition of Immokalee Workers (CIW), an intrepid group of tomato pickers in Florida who are battling the 5 trillion dollar global supermarket industry – and winning.
For a preview of the film, click here.


This industrial 2 light brushed nickel vanity light will add a retro feel to your home. The industrial look is created with metal shades in same brushed nickel finish which creates a perfect opportunity to showcase this fixture with some filament bulbs (not included) and really add a warm glow to your space. This fixture is mounted with stylish oval back plate and has straight arm detail. The ..
This industrial 2 light brushed nickel vanity light will add a retro feel to your home. The industrial look is created with metal shades in same brushed nickel finish which creates a perfect opportunity to showcase this fixture with some filament bulbs (not included) and really add a warm glow to your space. This fixture is mounted with stylish oval back plate and has straight arm detail. The option of reversible mounting gives you the option of focusing lighting where needed most.


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Q: Wiring an AJAX call in Knockout.js Apologies if this has been asked before, I have searched but I'm finding it very hard to express my problem in a search friendly way. And I can't figure it out from the knockout documentation, however it seems like a basic question.
I have 3 select lists and a Knockout view model. Selecting a value in the first list updates an observable in the view model. I then need to make an ajax post, sending that value to the server and retrieving a list of values which I put in an observable array in the view model, which will in turn update the other 2 lists.
I'm happy with wiring up to observables and that part is working fine, my question is how and where to trigger the ajax call.
If I trigger it on the change event of the first select it seems to cause a race condition which means it sometimes gets called before the view model has updated.  I could trigger it without using the observable, but that doesn't seem very knockoutish.
If I use a custom binding for retrieving values it will cause the ajax call to be made twice and I can't put the retrieval in a function because it needs to run asynchronously (and it would be called twice).
I feel like I need something which listens to an observable and triggers an ajax call without any visual element.
Any help would be gratefully received.

A: Triggering things that should happen in response to view model changes generally works through subscriptions in knockout.
function ViewModel() {
    var self = this;

    self.someValue = ko.observable();
    self.otherValue = ko.observable();

    self.someValue.subscribe(function (newValue) {
        // do something with newValue, like an Ajax request.

        // assuming jQuery
        $.get("your/url", {val: newValue})
        .done(function (data) {
            self.otherValue(data);
        })
        .fail(function () {
            alert("could not retrieve value from server");
        });
    });
}

redpajama_set_name: RedPajamaStackExchange


text:
Biggest Estate on Earth
Author(s): Bill Gammage
Across Australia, early Europeans commented again and again that the land looked like a park. With extensive grassy patches and pathways, open woodlands and abundant wildlife, it evoked a country estate in England. Bill Gammage has discovered this was because Aboriginal people managed the land in a far more systematic and scientific fashion than we have ever realised. For over a decade, Gammage has examined written and visual records of the Australian landscape. He has uncovered an extraordinarily complex system of land management using fire and the life cycles of native plants to ensure plentiful wildlife and plant foods throughout the year. We know Aboriginal people spent far less time and effort than Europeans in securing food and shelter, and now we know how they did it. With details of land-management strategies from around Australia, The Biggest Estate on Earth rewrites the history of this continent, with huge implications for us today. Once Aboriginal people were no longer able to tend their country, it became overgrown and vulnerable to the hugely damaging bushfires we now experience. And what we think of as virgin bush in a national park is nothing of the kind.
On Order:
Explodes the myth that pre-settlement Australia was an untamed wilderness, revealing the complex, country-wide systems of land management used by Aboriginal people.
Winner of ACT Book of the Year Award 2012 and Prime Minister's Prize for Australian History 2012 and Victorian Premier's Literary Award - Nettie Palmer Prize for Non-Fiction 2012 and Queensland Literary Awards: University of Southern Queensland History Book Award 2012 and Manning Clark House National Cultural Awards, Individual Category 2011. Shortlisted for NSW Premier's Literary Award Douglas Stewart Prize for Non-Fiction 2013 and ABIA Australian General Non-fiction Book of the Year 2012.
"This bold book, with its lucid prose and vivid illustrations, will be discussed for years to come." --"Australian Book Review"
Bill Gammage is the author of The Broken Years: Australian Soldiers in the Great War.
Contents Illustrations Thanks Sources Abbreviations Definitions Foreword by Henry Reynolds Australia in 1788 Introduction: The Australian estate 1. Curious landscapes 2. Canvas of a continent Why was Aboriginal land management possible? 3. The nature of Australia 4. Heaven on earth 5. Country How was land managed? 6. The closest ally 7. Associations 8. Templates 9. A capital tour 10. Farms without fences Invasion 11. Becoming Australian Appendix 1: Science, history and landscape Appendix 2: Current botanical names for plants named with capitals in the text Notes Bibliography Index
Weight (g) : 1.0478
Publication date : March 2012
Availability date : August 2012
Author : Bill Gammage
Edition : Main
Dewey classification : 305.89915
Illustrations : illustrations


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Wendy McNerthney was the longest-serving nurse at the Bailey-Boushay House, the only local place that provided end-of-life care for patients with AIDS in the '90s. In the first four years she was there, hundreds died and no patient was ever discharged.
It's a little easier now.
But back in the early '90s, someone died every 72 hours at the Bailey-Boushay House in Seattle's Madison Valley.
AIDS. It was always AIDS. The year that Bailey-Boushay opened, it was the No. 1 cause of death for men aged 25 to 44 in the United States. Half the people who died of AIDS in King County died at the facility.
Wendy McNerthney was there for almost all of them, bearing witness to one of the worst health-crises the country — and the city — had ever seen.
"It was like a plague," McNerthney, 64, said recently. "I just thought, I can take it one day at a time, one hour at a time. Many times I came home sobbing.
After more than 24 years, though, McNerthney has retired from Bailey-Boushay. She was the longest-serving nurse the facility has had, having spent more than two decades tending to patients and sitting with partners who would eventually become patients themselves.
She comforted relatives who would come straight from the airport or the road, struggling to absorb what came in three, stunning blows: Their son was gay. Their son was sick. Their son was dying.
McNerthney arrived at Bailey-Boushay in October 1992, six months after it opened — the first facility in the country devoted to end-of-life care for people with AIDS.
She had taken her nursing exams in July of that year, and while she waited for her results, worked as a graduate nurse at a nursing home in North Seattle.
But she kept thinking about the patients at Bailey-Boushay, a place she had heard about from one of her professors.
She arrived to find patients ranging in age from their 20s to their 70s. The average stay was four to six weeks, during which 80 percent of the patients burned with fevers that reached 103 degrees.
For the first four years she was there, no patient was ever discharged. They just died. One every 24 to 72 hours, adding up to about 300 deaths a year.
McNerthney administered cold packs and spent night shifts making protein milkshakes with two or three blenders going at once. She touched patients with lesions caused by Karposi's sarcoma, a cancer that developed on lymph nodes. She stayed close.
"I wasn't scared," she said. "You learned good standards of care — hand-washing, gloves, gowns and isolation carts.
Most of the patients came straight from hospitals.
"There was no other place," said Knowles, the executive director, adding that some home-care agencies and hospice facilities wouldn't accept patients with AIDS. If they did, those patients received minimal or no care at all. Nurses refused to touch them. Dietary workers refused to go into their rooms and left their food trays stacked by the doors.
At Bailey-Boushay, 35 patients received round-the-clock care and were even allowed to bring in their own furniture. One patient's room was featured in Metropolitan Home magazine.
"She remembered everybody, and all the years she has been here, the sensitivity and the warmth …" he said. "She is so genuine. And when she looks at you, you can tell she's right there with you. You can see it on her face.
McNerthney was born in Winnipeg, Manitoba, and moved to Everett as a child. Her mother died when she was 15, and she looked after her younger siblings.
She was raised Lutheran, but religion didn't matter to her when it came to caring for people who had been condemned from the pulpit, by politicians and by people in McNerthney's own circle.
"I had no moral struggle with the disease," she said. "It's the people you were taking care of. So it was all about education.
Even though the number of AIDS deaths has decreased and the disease is seemingly under medical control, things are no easier for McNerthney and her colleagues.
Bailey-Boushay now provides end-of-life care primarily to those with cancer, ALS and Huntington's disease.
Now that she's retired, she is planning a trip to Ireland with her husband, Pat, and might return to Bailey-Boushay as a volunteer. No matter her plans, the patients and the place will stay with her.
Or, she said, whether it will come at all.


The origin of our products lies in the development of CMOS ICs for quartz watches. We downsized quartz mechanisms from the size of a locker to something small enough to be worn on a wrist, and succeeded in bringing to production analog semiconductors that function accurately while using only a minute amount of energy. The safe and reliable leading-edge technology cultivated through our research and manufacturing is seeing increasing utilization in the latest key devices, including those for automobiles, smartphones, and healthcare.


The land in Lacole, part of the Oromo Region in southeast Ethiopia, looks like it's literally been torn apart.
The effects of unpredictable rains and erosion — made worse by the major drought the region has been struggling with this year — have formed a deep rift that cuts across a huge swathe of the valley. And until recently it had been getting bigger every month: long periods without rain caused land to dry out and crumble, only to be swept away when brief but intense rains came and fast-running water hit the area on its way from the surrounding hillsides.
I travelled to Lacole this weekend, at the beginning of a trip that will take me to some of the parts of the Horn of Africa hardest hit by the current crisis. What I saw was a clear example of how Mercy Corps is making a real difference for a community that has been living at the mercy of the elements.
The rift's advance had kept local people without reliable water sources and forced them to leave the land uncultivated. The condition of the land was so unstable that they couldn't use it for grazing their livestock, or even plant crops for fear young plants would either die in extended dry periods or be swept away when rain water rushed in unchecked, taking any remaining good soil with it.
To help, Mercy Corps has ramped up a major response helping the community find ways to channel, store and use what rain does fall, make the most of the land and stop the growing rift in its tracks.
As part of this work, I saw hundreds of pits, trenches and banks of soil that have been dug across the area to catch and make the most of the water across the dry months. More than 360 cubic metres of small stone dams have been built at strategic points to keep water where it should be when it finally arrives, rather than destroying crops and causing havoc. The dams and soil banks have been reinforced by planting grasses and crops around them that not only keep soil from being washed away and store much-needed moisture after the water recedes, but can also be used to feed livestock and harvest for sale.
Even better, the wages for getting all this work done have gone straight to the community who'll benefit from the work. Local people did all the work themselves and — as well as getting direct benefit from the changes in the long term — Mercy Corps gave them a fair wage for all the work they put in so they can use the cash to buy the things they need in the short term.
The preparation for this work began well before the rains failed and caused the current crisis — the local community and Mercy Corps knew the risks were real and started work almost a year ago. As a result, and thanks to the enthusiasm of the community involved, the work is now nearly complete. Finally, the community face the future much better prepared for both drought and the rushing rain water that can follow, and the rift has stopped growing.
Erin Gray is Senior Media Communications Officer for Mercy Corps' European headquarters in Edinburgh, UK.