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Horror / Film
Chilling Visions: 5 Senses Of Fear
Released: October 22, 2013 • Available in US & Canada
Formats Blu-ray
From the people that brought you Steve Niles' Remains and Dead Souls comes a terrifying new anthology film based on the human senses…
SMELL – Directed by Nick Everhart. Left by his wife and stuck in a dead-end job, Seth Kyle's life is the definition of undesirable…until a mysterious saleswoman shows up at his door offering him "a scent to die for." Armed with a new air of self-confidence and a never-ending barrage of attention, Seth quickly learns that the smell of success comes with a deadly price.
SIGHT – Directed by Miko Hughes. Unsatisfied with his own version of reality, an optometrist develops a machine that can harness the visions of all of his patients. In an attempt to show his favorite patient's abusive boyfriend the error of his ways, the doctor injects a series of viciously brutal images into his mind, leading to a visceral bloodbath of reality and hallucinations.
TOUCH – Directed by Emily Hagins (My Sucky Teen Romance). After a car accident leaves him stranded in the middle of nowhere, a 12-year-old blind boy stumbles into the stomping grounds of a sadistic serial killer. Using his memory and strong sense of touch, he must navigate through the unfamiliar territory as the killer quickly closes in.
TASTE – Directed by Eric England. A street-smart hacker is brought in for a job interview with a mysterious corporation. He soon learns that the company is led by a man-eater who has impeccable taste…and doesn't take "no" for an answer.
HEARING – Directed by Jesse Holland and Andy Mitton (YellowBrickRoad). While researching an urban legend about a song that's long been thought lost, a group of friends piece together all the existing recordings of it, bringing it back to life for the first time in decades. Before long, they discover the bone-chilling truth of what happens to anyone who listens to it and why it was buried for so long.
Andy Mitton Director
Arnie Holland Producer
Bonnie Farley-Lucas Producer
Caleb Barwick Actor
Emily Hagins Director
Eric England Director
Jesse Holland Director
Miko Hughes Director
Nicholas Tucci Actor
Nick Everhart Director
Richard J. Lucas Producer
Shane O'Brien Producer
Symba Actor


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Home Creepypasta 10+ Absolutely Chilling Encounters With Creepy Humans
10+ Absolutely Chilling Encounters With Creepy Humans
David Wray
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Remember how your parents used to tell you not to interact with strangers? Well, that culture became completely eradicated with the introduction of the internet. What do you know, your parents were right after all! The following are 20 utterly terrifying encounters real people had with actual strangers. Read on to discover an entirely new phobia.
I gave a ride to someone who ended up getting executed for murder
"When I was in college a friend introduced me to a friend of hers. The guy was not bad looking but had a 'story.' He had been in some trouble with the law but was trying to get himself together. He was taking some classes to try to improve himself. I ran into him while getting gas one day and he asked me for a ride. I didn't feel good about the guy but gave him a ride to school. He started talking about how much he wanted to go straight. He talked the way people talk when they are trying to make you believe they are something other than what they are. And he told me he couldn't believe he was talking with a girl like me (not a criminal?) I dropped him off and told myself to stay clear of him if I saw him again. For a while, I would see him on campus and always escaped crossing his path and did not acknowledge him. A couple of months later he disappeared, and I no longer had to watch for him. I didn't ever see him again. But two years later I read about a murder in town; it was he who had killed a man by stabbing and cutting him because of a bad drug deal. He was convicted and sentenced to death in Oklahoma. He was executed a few years back. I read an interview with him before the execution; he had no remorse and was frighteningly callous about his actions and his death. At that time, he no longer even resembled the young man I had given a ride. I learned to trust my instincts." — pleased2b
We saw a man who did not look human
"My husband and I left Target late one night (almost closing time), and since it was winter time in Chicago, my husband was fine with me getting in the car to warm up while he loaded the back with our random assortment of Target goods. The parking lot was relatively empty except for the car parked directly in front of us.
I look at the car and notice a man sitting in the driver's seat. Not wanting to stare I look away, but then stop. He looked… Wrong. I look back at him again, and I get chills all over. My husband finally slides into the car, and I say, 'This guy in front of us… Do you see this?' He looks, goes pale, and says, 'What the f***…..'
He's not looking at us. He's not looking at anything. His eyes are so sunken as they look like black voids. His mouth is agape like he's sleeping, but it's just a black hole, no teeth or tongue. Now, this might just be due to obscured vision since it's nighttime, but we were right under a light, so he was fairly illuminated. The creepiest part was his skin. It looked simultaneously too loose and too taught. Think the cockroach alien from Men In Black when he's is that guys body. Some places the face was hanging off, others stretched tight. He looked like a thing wearing a human face. He wasn't moving, just breathing.
'Let's get the f*** out of here,' my husband said, obviously startled. We pulled out of there as quick as we could and triple checked the locks on our doors that night. We still get creeped out remembering that night. My husband is a huge skeptic and doesn't believe in the paranormal or anything outlandish, but even he knows something was unexplainable about that guy. Despite the name of this thread, he just…. Wasn't human." — This_Isnt_Progress
A friend threatened to slice me into pieces
Source: Mashable
"An acquaintance from high school and I met up one night to discuss holding an intervention for a mutual friend. He ended up running his hands over me, whispering, 'Slice, slice, slice, slice, slice, slice, slice… Slice… You know, normally when I think about killing people, I do it with seven cuts. I'd do eight cuts with you, and I like that symmetry.'" — neurotica_9000
A friend of a friend beat a girl, raped her, and left her for dead
Source: DeviantART
"A friend of a friend started hanging out with our group of friends. He was very good looking and outgoing, and all the girls liked him, except me. He made me very uncomfortable. I had no reason to feel that way, as he was always perfectly pleasant and never said or did anything wrong. I just took an instant dislike to him. About 4-5 months with him hanging out with us, he asked a girl at our party to take him to get cigarettes. She did, and when they didn't return, everyone thought they were just hooking up. Oh, they hooked up alright. She was found in a farmer's field early the next morning in her car, freezing. Barely alive. He had beaten, raped her and half a bit off one of her ears. Her girly bits were mangled because after he raped her, he used a knife as a dildo. She was in the hospital for a month and could never have kids. He went to jail, and 25 years later, I run into her sometimes. She is married and seems pretty happy. I have no idea what it took to get her to this point, but I'm happy that she was able to move forward." — katgib13
I spoke to a little girl who was planning a school shooting
"I was in a holding area for minors that needed to be taken out of society for a few days. It was one room with a couch, a TV and a table and chairs. It was nice.
Met a girl and she asked me to braid her hair. I was braiding her hair and asked her why she was there. Some kids were there for drug withdrawals, physically fighting a parent or suicide. She said she got caught planning a school shooting and gave me a detailed rundown on how her friends and she were going to try to take out as many kids as possible then kill themselves." — ChilledButter13
A lady was passed out and tied up in the back of this man's van
"This happened to my brother ~23 years ago, not me, but it still freaks me out when I think about it. He was about 12 or 13 and angry at our parents for whatever reason, so he decided to walk a couple miles to a gas station/little store. It was about 8 o'clock at night, and our neighborhood wasn't too bad – usually safe.
Well, he's walking down a side street, and an old beat up van pulls up right beside him and stops. The driver slid open the side door and called my brother over. As an adult, he later said it smelled like sulfur and copper mixed and made him sick to his stomach. This creepy, greasy, middle-aged guy says to him, "Check this out." So brother peaks behind him and is shocked to find a passed out, naked lady tied at the wrists and ankles. The man whispers, 'You wanna take a ride on her?' (or something like that – can't remember exact wording) And my bro snapped out of his shock, turned and ran straight to the gas station where he called our parents. Our dad was pissed he had to drive two whole miles (OMG) to pick him up at nine at night and would not listen to or believe his story, at all.
Now my brother can be full of s*** sometimes, I'll admit this, but I specifically remember a night Dad came home pissed and brother came home white as a ghost, shaking, and it looked like he'd been crying. Years later he told me what happened that night, and he has a strange theory about the guy, but I won't go into it. He still hates our parents for not believing him and calling the police. And he still gets sick when he smells boiled eggs/sulfur smells." — TittieMilkTittieMilk
My girlfriend's father had an evil energy
"My high school girlfriend's father. He was an older dad, 68 at the time, and had grown lazy and senile after 20 years of beating his wife and two kids. He resented their existence, having never wanted kids, to begin with, and the entire house reeked of a living nightmare.
The first time I entered their house was the closest thing I've ever had to an ESP experience. I could feel weird evil energy all around me and tears were streaming down my face." — introversed
A murderer held my baby girl right after she was born
"A notorious murderer in my city was a security guard at the company where I worked before he was identified and caught. After he was apprehended, we discovered that he had kept the body of a small child in a cold water tank on the premises, just a few tens of yards away from where we worked. It had been there two years or so but was never found or even suspected, until he had given the information to the police.
The man is still in jail nearly 25 years later. It has since been proven with DNA that he was responsible for several area murders. He is serving compound life sentences.
He was very friendly with me and with my colleagues as we came in and out of the building every day. He smiled and joked with everyone. In fact, the two of us had an ongoing morning gag.
While he still worked there and well before his crimes were discovered, my baby daughter was born. My wife and I brought her into the office to show her off. I let this security guard, who was the father of an eight-year-old himself, hold the baby – as the body of a toddler, he murdered a few months before lay decomposing a couple of rooms away.
When he gently handed my daughter back to me, doing so as perfectly well as any experienced parent would, he told me she was beautiful and that I must be proud. I sure was.
He held my baby. Dear God, he held my baby." — jcartier2
A woman saw an invisible presence on the train
Source: CreepyPasta
"I was on the train (red line for you Chicago homies) one late night after my shift at the hospital and this old lady who was presumably sleeping woke up as I sat across her. She had super glazed eyes and then started going "little girl, you can't sit there, he's sitting there…" Mind you; nobody was in this train cart. And then she continued to go "little girl… little girl…" (I'm a 5 ft 22-year-old woman). I ignored her because I was only a few stops away and then all of a sudden she started screaming at the top of her lungs "LITTLE GIRL GET OFF THIS TRAIN GET OFF THIS TRAIN TRAIN TRAIN," and you bet my ass ran the hell out of there in the next two mins as the train stopped." — tinkblazed
An older student went to jail for beating up a teenager
Source: Odyssey
"When I was a senior in high school this 20-year-old transferred to my school. He had failed a bunch of grades.
This guy seemed normal enough at first. My friends and I had him over once and were lifting weights in my friend's garage. This guy claims that he is a cage fighter, and challenges one of us to fight him. This guy was not a cage fighter. My friend that did wrestling for four years pinned him in about 15 seconds. This dude went insane. Started throwing s*** around the garage and said our friend had cheated. He said he was gonna get his pistol and come back to settle the beef. Never came back.
He drove a ratty old truck to school but would tell everyone that he drove a 67 Chevelle SS 396.
I used to drive my friend's sister to school who was a sophomore at the time; he wouldn't drive her for some reason. They lived down the street. She was waiting outside one morning, and this pyscho is driving down the street. He floors it and tries to run her down. He was dating a girl (15 y/o) that didn't like my friend's little sister and thought that trying to run her over was a good way to deal with it.
My buddy and I prank called him while at lunch one day after we learned how crazy he was. He was in the gym at the time. We were talking s*** calling him weak and a coward etc. He goes nuts and starts screaming at the top of his lungs how he's gonna get his AR15 and deal with us. He had no idea who we were. Also some s*** about him being a cage fighter. He got suspended.
He never did graduate. Got a few months in jail for beating the s*** out of a 14-year-old. He also got that 15-year-old pregnant and just left town. Haven't seen him since." — Nitrothacat
A stranger knew way too much information about me
Source: The13thFloor
"I was young and browsing around on Omegle (video). Some random stranger started talking to me and revealed an incredible amount of information about me. Beyond the usual IP address trick that you can tell where the other person is from. I have a relatively low internet profile. This guy knew everything about me, from my father's name to my best friend. I go to college for computer science, and still, have no idea how this stranger knew so much about me. It was the scariest thing I've ever seen in my life." — Throwaway10873
A classmate asked me to help murder her boyfriend
"I was in college and waiting between classes. One of my female classmates for a speech class came up, and we had a conversation. This was in a nearly empty hallway by the classroom. It ended up going from the class we were into true crime to her boyfriend.
I remember the one comment and the question that made things weird clearly: 'If I ever find my boyfriend cheating on me, I'll murder him. If that even does happen, since you know a lot about true crime, could you help me get rid of his body?'
That was all said in a serious voice. There was an awkward silence as I mentally asked how likely it would be that she'd kill me if I said 'No' and went to the cops.
I ended up flat-out refusing, saying I didn't want to go to prison, and saying she shouldn't ask that sort of question if she didn't want to go to jail either. She accepted my refusal. However, I also didn't tell the police because I knew she was smart enough to be able to figure out who did go to the cops and I didn't want to be killed. I ended up avoiding her after that as much as possible – I don't know if she ever did murder her boyfriend or not either. That's the creepiest person I've met." — RandomCashier75
My high school teacher was arrested for pedophilia
Source: The Occult Museum
"That I knew? Must have been a teacher I once had during my first two years in high school. Never liked him, he had a very creepy vibe. 3rd year I heard he was behind bars, he got caught trying to lure a 12 y/o boy to 'meet' him." — Magdalen
I picked up a hitchhiking murderer
"This dude I picked up hitchhiking who said I looked like the woman he killed then thankfully made me drop him off right then as it seemed he was fighting the urge to kill me. Dodged a bullet that day." — bladerunnet263
My customer made pornographic photographs of children
Source: Weasyl
"We had a creepy guy making pornographic images of children come in to get his film developed back when I worked in a chemist/ photo lab. Why he opted to get us to develop his pictures is beyond me. This would have been around 2009 so digital cameras were very much a thing as well.
He was a creepy guy anyway and gave me the heebie-jeebies when he dropped the film in. He was huge, both tall and broad. His clothes were fake fur and were falling apart. His face was almost completely hidden under a huge and extremely tatty deerstalker.
We realized what his photos were aa soon as we developed them and called the police. They left a couple of plain clothed officers in the store for when the guy came back for his pictures with more uniformed officers waiting in their van nearby. Because I'd already dealt with the guy and would recognize him, I was stationed at the counter to wait to him. I had to pretend his photos weren't back yet (not entirely uncommon when people used the 1 hour service at busy times) and to tell him I was going to the lab to look for them. He came in, I said what I'd been told to say and went out the back to the manager and police. The guy was taken away in their van. No idea what happened to him after that. Utterly disgusting man." — strawberrypops
A prisoner violently murdered a woman
"I was a jailer in the 1990's, and we had a prisoner who was convicted of violently murdering a woman. It was a random thing, not a domestic or drug incident. He'd had a prior for assaulting a different woman. This guy would have been a serial killer if he wasn't a complete moron. In just regular conversation with him (meals, moving to exercise area, etc) that guy creeped me out severely. I've never gotten such an evil vibe from a person before, and that's after more than two decades of police work." — MattsWorldoWonders
A classmate attacked multiple women — and it didn't surprise anyone
"Dude I went to university with. He was very good-looking, athletic, intelligent and personable, but there was always something 'off' about him that you couldn't put your finger on, but lots of people felt it. There was a running 'random' joke to the effect of him being a serial killer, with no apparent reason behind it, that kind of thing.
15 years later and gu As who ended up going American Psycho on a couple of prostitutes?" — Jiktten
My step-father molested his teenage daughter
"My stepdad. I never felt safe around him, and I avoided him at all costs.
It turns out he got his teen daughter pregnant and molested my sisters, too." — Texastexastexas1
A man put his fingers to his head and made a gun motion
"For me, the creepiest human would be when I visited Copenhagen. I was in the Metro subway, and he asked me for money. I didn't have any change, so I apologized and said no. He lingered around after this and wouldn't go away. He then proceeded to follow us. Once I hurried down the escalator, I looked up, and he was stood there looking down at me while I descended. He put his fingers to his head and motioned a gun action.
Luckily nothing happened after that, but it made me feel uncomfortable." — dino-claw
A car followed me for blocks when I was still a teenager
"When I was in high school, about to turn 18, I was in our bookstore scoping out the recent edition of whatever nudey magazine I was going to buy for nudey magazine 18th bday. Noticed someone staring at me infrequently in a very obvious manner, thought nothing of it and kept going about my business, got coffee and bounced. Driving home, glanced in the rear view mirror and noticed the same dude in an older model Buick following me relatively close. Again, felt coincidental then a few more miles down the road the same car was right behind me… time to ditch the tail. Went into a grocery store parking lot, got out to go into a public place…when I got back into my truck with some random chit, Buick was waiting in the corner of the parking lot. Still a Coincidence? Not a chance…back in the damn truck to ditch the Buick still following me. Heart rate going up thinking about dafuq to do… Drove out of the grocery store not towards home but a local police station and once there was a sign for a police station that I'm guessing he noticed, he turned off. Always felt like I was being followed for years after that." — ichthyohead
If you no longer feel like interacting with just about anyone you do not know yet, we completely understand. The horrors that you may encounter from other real humans surpasses all other forms of horror. Time to become a hermit!
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redpajama_set_name: RedPajamaCommonCrawl


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Realfilm (engelsk: live-action) beskriver typisk en spillefilm med levende skuespillere uden animation. På trods af det bliver udtrykket dog også brugt til at beskrive film hvor mennesker og tegnede karakterer optræder sammen, såsom Mary Poppins, Hokus Pokus Kosteskaft, Hvem Snørede Roger Rabitt? og Space jam.

Film

redpajama_set_name: RedPajamaWikipedia


As promised, here are a couple more pictures from my bathroom makeover reveal (you can see the first post here). The chest of drawers was a freebie from friends of my my parents – it was covered in dark brown paint! I managed to get most of it off before painting it, and sanding it back to reveal the pine underneath.
I'm off to Spain with some friends for a girls weekend tomorrow, and I'm so looking forward to it! I fully intend to sit by the pool and read a trashy novel!
In other news, I have managed finally to book a builder to come next week and start some work on my kitchen which is very exciting! I hope to update you with some pictures next week.
Next Post My Kitchen Saga!


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84 Sculptures of Men Stand on the Edge of Buildings in This Haunting Anti-Suicide Campaign
Striking images mirror a disturbing U.K. statistic
Adam&eveDDBs haunting, yet effective stunt to prevent male suicide. Campaign Against Living Miserably
By Gabriel Beltrone
To combat male suicide, a nonprofit has put 84 humanoid sculptures on top of a skyscraper and other building in London—the same number of men who take their own lives every week in the U.K.
The effort, titled Project 84, was created by the Campaign Against Living Miserably, or CALM, which teamed up with London agency adam&eveDDB and American sculptor Mark Jenkins.
They cast the sculptures with tape, using a technique for which Jenkins is famous, and created them with help from friends and family of men who have committed suicide.
The images are harrowing and haunting—visible atop ITV's studios in Southbanks. Installed on Monday, they will remain there throughout this week. The TV network is supporting the campaign with programming about suicide, including interviews with surviving loved ones. Public relations agency W Communications is also contributing to the awareness push. Male grooming brand Harry's is a sponsor of the effort.
The goal is to increase conversation and reduce stigma about the issue, as well as generate more resources to support men at risk of harming themselves. A website for Project 84 features video, photos and stories from the friends and family of men who committed suicide. It also includes a petition, as well as a link to a helpline for men who are struggling with mental health. "Things can get tough, but we can help you get your life back," it reads. "Being silent isn't being strong."
Also included are pointers for people who are concerned about a loved one, and links to bereavement support for those affected by suicide.
In the U.S., one recent sweeping suicide prevention campaign from the Ad Council encouraged young people broadly to be proactive in checking on their friends and loved ones. That's not to mention rapper Logic's ad with Google during the Grammys, themed around his hit song named after the National Suicide Prevention Lifeline's phone number.
If, by contrast. CALM's focus on men—as opposed to suicides of all genders—seems confusing, some context may help. As of 2016, roughly three-quarters of suicides in the U.K. were male, according to the country's Office of National Statistics.
"As a society we have to face this awful issue, discuss it and actively work to stop it," says Simon Gunning, CEO of CALM, in a statement accompanying the campaign launch. "Project 84 is all about making the scale of the situation very clear, and we hope it will drive change and encourage everyone, government included, to come together to take suicide seriously."
Add Ant Nelson and Mike Sutherland, deputy executive creative directors at adam&eveDDB: "Male suicide and mental health is a big issue that can't be ignored any longer. It's unacceptable that so many men are tragically taking their own lives every week, and yet there are so few people talking about it. Hopefully this piece of work will highlight this shocking statistic and help start conversation."
Gabriel Beltrone
@GabrielBeltrone gabriel.beltrone@gmail.com Gabriel Beltrone is a frequent contributor to Adweek.


If you look carefully into this shot you will see the river reflections running through the middle. The East Coast is famous for scenes like this–fall at its prime. These gorgeous oak trees spread their branches over the river and the delicate ferns in the foreground glowed yellow after a fresh shower of rain. A few red leaves transformed this image into a magical land. I used a polarizer to reduce the glare and disperse the spectrum. I felt a special mood as I nestled my camera amongst the ferns and carefully composed the shot. Moving the tripod only inches changed things dramatically. This was the spot. I pressed the shutter and watched the river flow. It was a magic moment.


Beware, your Sunday is about to start the best possible way! We announced it yesterday with Danny Sommerfeld's Galerie, –he's the TPDG Supplies main man– here stands, as a LIVE exclusive, the newest video production from the German gang. And boy, you're in for good stuff… The street skating we all dig, tech or raw when needed, with both power and finesse. Add a custom track by Figub Brazlevic, and you are in for a couple of motivational viewings before getting out the house! Enjoy the click. Oh, and Danny shuts down a famous spot, in the most glorious manner in here!
Danny Sommerfeld puts us in the mood for their new TPDG Supplies production, to be premiered tomorrow on LIVE!


Now that you know what a art deco wall mirrors can do and also have an idea about what you want it to look like. Visit an expert about mirror once, and then change your mirror to does one a favour, besides being there, being quite and helping you to navigate easily throughout your home. You shouldn't believe that mirror are just for designs inside the house. With the countless kinds of patterns and colors, additionally they complement your whole space. And therefore so you are ready to get the art deco wall mirrors with the styles you've in mind. Make sure to buy from a store that presently features a reputation of having quality mirror. You can even buy online but be sure to read the great print as it pertains to the shipping fees.
This has been learned of which art deco wall mirrors's colors have an affect on your moods. Yellowish mirror is connected with remaining dazzling and also pleasing; green as pure and relaxing; violet together with brilliance in addition to luxury; blue-colored while trendy plus calming in addition to red-colored because radiant and also exciting.
Before you decide what art deco wall mirrors goods you'd prefer to buy for your space, you should get several points intoconsideration. Firstly, what paint and products are you wanting your mirror to be? Do you want every thing to be solid wood? Steel? Decorated a solid scheme? You can find many alternatives to pick from, that this is the hardest portion of your choice. If you decide on wood, one of the best types of wood for furniture is oak for the durability. Oak mirror can be specially attractive. One the other hand, if you like metal furniture make certain that you decide on goods which can be all related in tone. With furniture that is painted strong shades, the choices are pretty much countless, but you must choose just a couple of colors to prevent being confused by them.
Yet another thing to consider is the total amount of place that will come in your area. Ensure that to get dimensions of your area and all of your furniture. That you do not want to purchase something that won't fit. One method to get this simpler is by using grid report to draw out a layout of one's space and where you want to place each piece of mirror. Especially, choose furnishings that match your personality. Your art deco wall mirrors must certanly be haven for you, therefore be sure you like everything in it.
Choosing the right art deco wall mirrors for your mirror is a matter of taste and style and really should match the style of your mirror. From antique, to minimalist, there are dozens of styles to select from that will enhance the design of your mirror. So, some mirror and furniture stores will offer a big variety of mirror and colours to go along with them, it pays to go to small local mirror stores if you are looking for something classical to fit the old-fashioned feel of your house.
Do you want to get perfect art deco wall mirrors? Having said that there are more than one great process or ways to furnish and decorate your home and choosing the perfect art deco wall mirrors for your mirror will help making any room amazing.


Meal Prep a healthy week's worth of Egg white bites.
With a total value at over $76 - this initial Outdoor Box from Outdoor Box Club makes it completely worth the value.
Sound Barrier Hunting, is it a noise suppressant or bust?
A $15 product that could save a hunt from being busted. Sound Barrier Hunting is solving a problem almost every hunter has faced; being busted because you've made one false move.
The Roo Outdoor Inferno Terrain is the perfect hand warmer and should be one of the first accessories you think of when gearing up for cold weather hunting!
Cirrus Wind Indicator is the only wind indicator on the market that is affordable, safe to travel with, and you can check the slightest wind and thermal winds.
As Fred Bear said, "A Hunt based only on trophies taken falls far short of what the ultimate goal should be."


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Q: ActionScript Get All Network Activity? Is there a way within ActionScript 3.0 to:

*

*Get all URLRequests() that are made within the application?

*Get all RTMP:// connections to a Flash Media server?

Since my application contains SWC files which were compiled by another developer, I cannot directly access the ActionScript which creates the URL requests and RTMP connections.
Thank your for your time.

A: *

*You can use a web debugging proxy to monitor all messages that are sent over the wire. I like to use Charles because it deserializes AMF messages so that you can read them. It's not free, but you can use it as long as you want anyway. You'll just get an annoying delay every once in a while.

*Firebug has a lot of functionality built-in (even for Flash remoting). Go to the 'Net' panel and you'll see a 'Flash' tab. Your application has to run in the browser for this one though, not just in the standalone debug flash player.

*If you're using FlashBuilder, it has a view called 'Network Monitor' that does the same thing. I still prefer Charles though because it has more features.

*Adobe just released SWF investigator on Labs, which seems to allow you to take your compiled swc's apart as well as intercepting AMF messages. I can't tell you more since I've never worked with it. (props to @Eduardo for this one)

redpajama_set_name: RedPajamaStackExchange


On Thursday, the whole of our Year Six went to Crucial Crew in Rotherham. At Crucial Crew we learnt about road safety, first aid, the dangers of house fire, how to travel safely on a bus and about internet safety. We had a really fantastic time and experienced many different scenarios that were designed to make us think about staying safe. Below are just a few of our many pictures and a few quotes on what we thought about it all and about what we learnt.
In the first aid training, we learnt about how to put somebody in the recovery postition and how to check if they were breathing.
We learnt in the courtroom that a child can be sentenced from ten years old! In the courtroom, we took part in a mock trial. Poor Elsie was sentenced to six months in prison for assaulting someone and for stealing beer from a shop.
"This was the favourite part for me as we got to see what a real prison cell was like. It is not somewhere I would ever like to be. It wasn't clean and the toilet only flushed from the outside!"
"I thought this was the best scenario because you got to experiance what would happen if there was a fire on a bus. Dougie explained how to open the emergency door in a fire. He was very popular with all of the Year six children."
Here is a picture of some Year sixes experiencing some scenarios on the bus.
Y6NL enjoyed Crucial Crew because: the set was very realistic; the people who ran the scenarios explained things really well and treated us like adults; the scenarios and videos showed us what could happen and how we can keep ourselves safe; it was interesting, fun and not boring.


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Emerging antimicrobial resistance and newer tools to address the resistance
Pardeep Kumar Goyal, Ankita Semwal, Ajay Prakash, Bikash Medhi
Department of Pharmacology, PGIMER, Chandigarh, India
Date of Submission 19-Sep-2019
Date of Decision 21-Oct-2019
Date of Acceptance 07-Nov-2019
Prof. Bikash Medhi
Department of Pharmacology, PGIMER, Chandigarh - 160 012
DOI: 10.4103/ijp.IJP_607_19
Goyal PK, Semwal A, Prakash A, Medhi B. Emerging antimicrobial resistance and newer tools to address the resistance. Indian J Pharmacol 2019;51:291-5
Goyal PK, Semwal A, Prakash A, Medhi B. Emerging antimicrobial resistance and newer tools to address the resistance. Indian J Pharmacol [serial online] 2019 [cited 2022 Jan 19];51:291-5. Available from: https://www.ijp-online.com/text.asp?2019/51/5/291/271640
Antimicrobial resistance (AMR) is globally a serious threat in public health causing unfavorable effects which could be clinical (death or treatment failure) or economic (care cost and stay period).[1] The current data on antibiotic resistance are signaling to a difficult situation as this could land any country into drastic health as well as economic crisis. There is a global increase of 65% in antibiotic consumption in the year 2015 as compared to 2000.[2] It is estimated that by 2050, there would be a decrease in gross domestic product rate by 23.5% as a consequence of AMR.[1]
A political declaration has been adopted by global leaders including India at UN general assembly in 2006 which calls for global collaborative response to threat of AMR.[3] National action plan for AMR has been released by India which outlined various strategies to tackle AMR which includes awareness of AMR through effective training, optimizing the use of antibiotics in healthcare settings, promoting the investments for AMR research, reducing the risk of infection, and strengthening of Indian leadership on AMR. The national policy also mentioned proposal for color-coding antibiotic strips and newer molecules (carbapenems and tigecycline) to stop the use of these antibiotics outside the tertiary care hospitals. Red line campaign was launched in New Delhi in 2016 as central government has made it mandatory to display a 5 mm-thick red vertical line on packaging of prescription-only antibiotic drugs.[3]
Despite these efforts, AMR continues to increase and there is still a need to adopt more strategic plans in this regard. Various tools have been developed and adopted by many countries after recognizing the need for antimicrobial stewardship and rational drug use for antibiotics. These include tools which can diagnose infection or antibiotic resistance (diagnostic tools), tools to measure antibiotic consumption (surveillance tools), or tools to guide physician in selecting appropriate antibiotics (e.g., access, watch, reserve (AWaRe) tool, be antibiotic AWaRe tool).
Surveillance means 'The continuing systematic collection, assay and data interpretation in relation to health that would be essential for the purpose of planning, utilization and evaluation of the data in public health.'[4] Any variation in antibiotic resistance over the time can also be monitored with these tools. These tools aid in compiling data for antibiotic consumption which reflects the current situation of antibiotic use. Periodic measurement of consumption can increase the awareness among prescribers and policy-makers about antibiotic use and aids in defining the levels of optimal antibiotic use. These tools can also assess the impact of interventions. Data related to antimicrobial consumption can be measured with WHO-recommended defined daily dose (DDD) criteria or AWaRe tool.
Defined daily dose
WHO has recommended anatomical therapeutic classification (ATC) and DDD for the monitoring of drug utilization and the research for the improvement in antibiotic prescription and use.[5] In ATC, the active substances for drugs are classified in different five levels of hierarchy. DDD is the average maintenance dose/day for a particular drug, required for its main indication in adults. The DDD is based on reviews and available information of pattern of doses used in different countries. Prescribed daily dose may vary from DDD, and by applying DDD metrics, it is possible to examine changes in drug utilization of antimicrobials over time, make international comparisons, and evaluate regulatory effects.[5]
One DDD is designated as per ATC code and its route for administration. The DDDs for antibiotics are assigned on the basis of the average daily dose of ongoing treatment. Antibiotics for systemic use are classified under J01 category which are further subdivided for instance J01A (tetracyclines), J01B (amphenicols), J01C (beta lactam, penicillins), J01D (other beta lactams), J01E (sulfonamides and trimethoprim), J01F (macrolides), (lincosamides and streptogramins), J01G (aminoglycosides), J01M (quinolones), J01R (combination of antibiotics), and J01X (other antibiotics).[6]
Access, watch, reserve tool (AWaRe tool)
"AWaRe Tool" was launched with aim to use narrow-spectrum access antibiotics while reserving broad-spectrum antibiotics for "hardest to treat infections." AWaRe tool provides the recommendation about antibiotics for 21 most common infections. The WHO advised the adoption of AWaRe approach which classifies antibiotics into three groups.[7]
Access category
This includes narrow spectrum antibiotics of choice for the most common infections. In this group, maximum number of antibiotics belongs to β–lactam (52.63%), followed by aminoglycosides (15.78%), macrolides (5.26%), and tetracyclines (5.26%).
Watch category
These antibiotics are only indicated for specific limited number of infections and are more prone to the target of antibiotic resistance. These drugs are preferred over access antibiotics in serious infections. Beta lactams (54.54%) constitute maximum share of watch group antibiotics followed by macrolides (18.18%), aminoglycosides (9.09%), and carbapenems (9.09%).
Reserve category
These include antibiotics that must be used sparingly or preserved and used only as a last resort, when other options for antimicrobials get failed. The reserve group is majorly constituted of polymyxin (28.57%) followed by β-lactams (14.28%) and aminoglycosides (14.28%).
Surveillance of antibiotic consumption can be done by evaluating percentage of antibiotics prescribed from each above category. Other indexes which can be used to measure antibiotic consumption include amoxicillin index, access to watch ratio, watch percentage, and access percentage.[8]
» Access, Watch, Reserve Versus Defined Daily Dose as Metrics for Antibiotic Consumption
Complexity of DDD metrics requires specialist knowledge of pharmacological as well as therapeutic systems. Denominator data are not always available for the most commonly used metrics such as "Defined daily dose/1000 inhabitants/day" and it also demonstrates only limited information about quality of antibiotic use.[9] This metrics could not be useful to measure antibiotic consumption in pediatric population as there is a wide variation in weights in hospitalized children. On another hand, AWaRe tool can be simple easy to understand tool for physicians as well as policy makers. Application of this tool helps in accessing information about absolute and relative consumption of antibiotics which indicates overall antibiotic use in a country. This tool can be useful in measuring antibiotic consumption in pediatric populations by using various metrics.
Global antimicrobial resistance surveillance system
This surveillance system supports the global action plan for reduction in AMR. The aim of the tool is to support the global surveillance and analyze the data for strengthening the evidence to deal with AMR. Countries can participate in global AMR surveillance system (GLASS) by establishing AMR surveillance systems. GLASS focuses on eight most priority bacteria ( Escherichia More Details coli, Klebsiella pneumoniae, Acinetobacter spp., Staphylococcus aureus, Streptococcus pneumoniae, Salmonella More Details spp., Shigella spp., and Neisseria More Details gonorrhoeae) and 4 types of specimens (blood, urine, stool, and genital swabs) taken from patients. There are three core components of a national AMR surveillance system: a national coordinating center, national reference laboratory, and one or more surveillance sites. The data gathered at the surveillance sites flow through the national coordinating center to GLASS.[10]
Rapid diagnostic tests (RDTs) for infectious diseases have become an integral tool for antimicrobial stewardship program. These diagnostic tools have shown to decrease mortality, shorten hospital stay, and decrease healthcare costs. Study by Cals et al. in Netherlands demonstrated that diagnostic tests are cost-effective with cost saving of €22 per patient, and moreover, patients enrolled in intervention group required less antibiotics and less physician visits.[11]
Some of the RDTs are described as follows:
Resistance Plus GC
The Food and Drug Administration (FDA) has granted breakthrough status to this test which guide treatment decisions in treating gonorrhea with ciprofloxacin instead of ceftriaxone (broad spectrum and more prone to resistance). This tool detects both N. gonorrhea and sequences in the gyrA gene of the bacteria associated with susceptibility or resistance to ciprofloxacin.[12]
Accelerate pheno test blood culture kit
This diagnostic test can detect systemic infections and aid in the identification of suitable antibiotic within 6 h. This kit identifies different 14 species of bacteria and 2 different species of yeast that causes systemic infections, and also, it provides antibiotic sensitivity data for a subset of the identified organisms.[13]
Vidas brahms assay
US FDA has extended the use of the Vidas Brahms procalcitonin (PCT) assay to aid the physicians in decision to put a patient on antibiotic treatment or not in case of community-acquired pneumonia (CAP). This test uses PCT as a biomarker. It helps in antibiotic management decisions in patients with CAP. Low levels of PCT suggest a viral infection or other noninfectious cause of diseases whereas high titers of PCT suggest bacterial infection as a cause of disease.[14] Application of PCT kinetics as a decision maker tool resulted in less duration of treatment with antibiotics.[15]
Antimicrobial susceptibility test
FDA launched a tool that will give physicians direct and timely access to current updates about antibiotics. A new website by FDA will provide information about the antimicrobial susceptibility. This tool aids physicians in selecting an appropriate antibacterial drug to treat a patient's infection. The tests are based on criteria of "breakpoints" that help determine susceptibility of bacteria to various antibiotics. Any update about the breakpoints is usually shared by FDA through a website.[16]
Point of care diagnostics
This diagnostic test is performed directly on the patient at the time of consultation and aids physicians to prescribe antibiotic as per empirical therapy. For instance, the use of these rapid tests helps to diagnose the three major causes of death due to the bacteria (CAP [S. pneumoniae, Haemophilus influenzae, and Moraxella More Details catarrhalis], antenatal syphilis [Treponema pallidum] and tuberculosis [Mycobacterium tuberculosis]). This will help in preventing millions of deaths that are recorded annually in many developing countries.[17],[18]
Other RDTs include MALDITOF-Mass spectrometry, Xpert MRSA/SA blood culture (BC), FilmArray BC identification panel, verigene, prove-it sepsis, and the Unyvero BCU application.[19]
» Tools to Optimize Antibiotic Use
Be antibiotic aware tool
An effort was made by Centres for Disease Control and Prevention (CDC) against emerging antibiotic resistance and helps in improving the prescribing patterns and safe use of antibiotics. This tool disseminates information about rational antibiotic use in different settings as follows.[20]
Antibiotic prescription and usage in hospitals and long-term cares: CDC tool guides physicians in prescribing the right choice drug for a patient with right dose and timing. Appropriate use of antibiotics for long term can reduce rates of Clostridium difficile ection and antibiotic resistance
Antibiotic prescription and use on the farm: Antibiotic use on farms and administration of antibiotics to animals will lead to the production of antibiotic-resistant germs. Exposure of resistant bacteria is easily possible when people eat animal products contaminated with resistant bacteria and their products or by coming into contact with animal fecal matter. In US, every year, as many as 410,000 estimated food borne infections are due to antibiotic-resistant Salmonella and Campylobacter
Core elements of antibiotic stewardship: The unified approach cannot be implemented to optimize antibiotic use for all settings. This tool offers physicians a key set of principles to make efforts in the improving the use of antibiotics in different settings such as nursing homes, small critical access hospitals, and resource-limited settings. Important core elements included in antibiotic stewardship includes the leadership commitment, accountability, drug expertise, action, tracking, reporting, and education.[20]
Apart from its use as diagnostic tool, AWaRe can also aid physicians in prescribing appropriate antibiotic for particular indication. WHO has started the global campaign called "AdoptAWaRe, Handle antibiotics with care" to optimize the use of antibiotics. In G20 meeting on December 1, 2018, health ministers of 20 different countries had supported for implication and progress of AWaRe tool. Focus of this aware tool is to guide prescribers to prescribe more narrow spectrum antibiotics as compared to other two AWaRe categories to prevent resistance. By the end of 2023, WHO aims to support countries in improving antibiotic prescribing practices so that 60% of prescribed antibiotics should be from access category.[21]
» Antimicrobial Stewardship Metrics in India
Data of surveillance tools depict alarming situation in India. As per a surveillance report by WHO on antibiotic consumption in South East region of Asia, cephalosporins and quinolones were found to be most consumable with very high levels in some countries. As per report, there is a high-level consumption of third-generation cephalosporins.[22]
Recent two studies assessed the overall antibiotic use by using AWaRe categorization. Analysis of one day point prevalence survey antibiotic prescription data of 23,572 patients included from 56 countries was done by Hsia et al. The analysis data showed high diversity in the patterns of AWaRe antibiotic use among these 56 studied countries. In many regions of South-East Asia, the data for the use of antibiotics of access group were very high, as reported for the treatment of neonatal sepsis (74.2%) in Thailand, whereas the use of this group of antibiotics was comparatively lower in India (30.7%). More number of antibiotics were prescribed from watch group as compared to access group in Indian children with neonatal sepsis or lower respiratory tract infection.[8]
In a study by Hsia et al., access-to-watch index was evaluated to assess the oral antibiotic consumption of appropriate formulations among the children from different 70 countries. The results showed that access-to-watch index in India was <1 with lower access percentage (35%), higher watch percentage (47.3%), and considerable use of unclassified antibiotics (17.4%).[23]
Study conducted by McGettigan to analyze antibiotic sales between 2007 and 2012 showed worrisome results. Antibiotic sales increased by 26% in 2011–2012 as compared to sales in 2007. The study revealed the data in 2011–2012 for the sale of fixed dose combinations of antibiotics as: 499 million Units of antibiotics of access group, 367 million Units of antibiotics of watch group, and 3 million units of reserve group. Sales of antibiotic from AWaRe group had risen by 20%, 73%, and 174%, respectively, in 2011–2012.[24]
Study by Klein et al. to analyze the trends of antibiotic consumption revealed that among high-income countries, maximum consumers were US, France, and Italy while top consumers among low-/middle-income countries were from India, Pakistan, and China. The consumption of antibiotic is increased in India by 103% in 2000, from 3.2 billion to 6.5 billion in the year 2015. In India, the rate of antibiotic consumption has been increased from 8.2 to 13.6 DDDs/1000 inhabitants/day (63%).[2]
Pharmacovigilance programme of India (PvPi) is being conducted with the support of Ministry of Health and Family Welfare to keep records of adverse drug reactions (ADRs) for monitoring the safety of drugs.[25] Data can be collected from PvPi database to analyze frequency of Type F ADRs (unexpected therapeutic failures), and its relation with AMR can be evaluated.
Reintroduction of old antibiotics can be another alternative to fight drug resistance. As per the current situation of increasing multiple drug resistance to antibiotics and difficulty in the development of newer antibiotics, focus can be to reintroduce the 'abandoned old' antibiotics. For instance, the recent reports suggest that S. typhi is now more sensitive to older antibiotics as amoxicillin, trimethoprim/sulfamethoxazole, and chloramphenicol that belongs to access group of antibiotics.[26] Some old antibiotics as fosfomycin, chloramphenicol, rifamicin, fusidic acid, and many others can also be focused to reintroduce in clinical practices. Fosfomycin is found to be useful to treat vancomycin-resistant enterococci infections in intensive care, and fusidic acid is found to be effective against many strains of Staphylococcus. Chloramphenicols can be used as empirical therapy for patients with uncomplicated fever, and colistin/rifampicin combination can act synergistically against Acinetobacter baumannii and Pseudomonas aeruginosa infections.[27]
Recent study conducted in Delhi to evaluate availability of antibiotics showed unavailability of benzathine penicillin at primary, secondary, and tertiary healthcare facilities of public sector, and ampicillin suspension was available in only one-fourth of primary care centers.[28] Steps should be taken to ensure availability of good-quality antibiotics at all healthcare settings. This study also showed that median price ratio is more than 1 for amoxicillin, doxycycline, and erythromycin.[28] Hence, there is also a need to focus on easy affordability of antibiotics in developing country such as India.
There is also a need to promote manufacturing of new antibiotics by implementing various strategies such as providing incentives to pharmaceutical companies.
Antimicrobial stewardship metrics in terms of DDDs as well as access to watch ratio of antibiotic use is reflecting a serious situation in India. Appropriate policy decision can be implemented to adopt above tools in systematic pattern to combat AMR. Although surveillance tools can only aid in evaluating current resistance pattern, other tools including diagnostic tools, AWaRe tool, and Be antibiotic aware toolkit can aid physician for rational use of antibiotics which further leads to decrease in incidence of AMR.
Best strategic approach and proper utilization of available tools can help in fighting the evil of the AMR. Collaborative approach is needed for proper implementation of available tools in the best effective way.
Friedman ND, Temkin E, Carmeli Y. The negative impact of antibiotic resistance. Clin Microbiol Infect 2016;22:416-22.
Klein EY, van Boeckel TP, Martinez EM, Pant S, Gandra S, Levin SA, et al. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proc Natl Acad Sci U S A 2018;115:E3463-70.
Government of India. National Action plan on Antimicrobial Resistance. Available from: http://www.searo.who.int/india/topics/antimicrobial_resistance/nap_amr.pdf. [Last accessed on 2019 Sep 23].
Nsubuga P, White ME, Thacker SB, Anderson MA, Blount SB, Broome CV, et al. Public health surveillance: A tool for targeting and monitoring interventions. 02nd ed. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2006. Available from: https://www.ncbi.nlm.nih.gov/books/NBK11770/. [Last accessed on 2019 Oct 01].
WHO Collaborating Centre for Drug Statistics Methodology. Guidelines for ATC classification and DDD assignment; 22nd ed. 2019. p. 1-283. Available from: https://www.whocc.no/filearchive/publications/guidelines.pdf. [Last accessed on 2019 Sep 20].
WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index. Available from: https://www.whocc.no/atc_ddd_index/. [Last accessed on 2019 Sep 20].
World Health Organization. WHO Antibiotic Categorization. Available from: https://aware.essentialmeds.org/groups. [Last accessed on 2019 Sep 20].
Hsia Y, Lee BR, Versporten A, Yang Y, Bielicki J, Jackson C,et al. Use of the WHO access, watch, and reserve classification to define patterns of hospital antibiotic use (AWaRe): An analysis of paediatric survey data from 56 countries. Lancet Glob Health 2019;7:e861-71.
World Health Organization. AWaRe Policy Brief. Available from: https://adoptaware.org/assets/pdf/aware_policy_brief.pdf. [Last accessed on 2019 Sep 20].
World Health Organization. Global Antimicrobial Resistance Surveillance System. Available from: https://www.who.int/glass/en/. [Last accessed on 2019 Sep 21].
Cals JW, Butler CC, Hopstaken RM, Hood K, Dinant GJ. Effect of point of care testing for C reactive protein and training in communication skills on antibiotic use in lower respiratory tract infections: Cluster randomised trial. BMJ 2009;338:b1374.
SpeeDxIn vitro Diagnostics. Resistance plus GC. Available from: https://plexpcr.com/resistanceplus-gc/. [Last accessed on 2019 Nov 01].
Lutgring JD, Bittencourt C, McElvania TeKippeE, Cavuoti D, Hollaway R, Burd EM. Evaluation of the accelerate pheno system: Results from two academic medical centers. J Clin Microbiol 2018;56. pii: e01672-17.
US Food and Drug Administration. Press Announcements. Available from: https://www.fda.gov/news-events/press-announcements/fda-clears-test-help-manage-antibiotic-treatment-lower-respiratory-tract-infections-and-sepsis. [Last accessed on 2019 Sep 30].
Sarma P, Yadav S, Prakash A. Duration of antibiotic therapy: Fixed duration versus personalization/Individualization of antibiotic therapy duration: Which one to be preferred? BMJ Br Med J 2017. Available from: https://www.bmj.com/content/358/bmj.j3418/rr-36. [Last accessed on 2019 Oct 01].
US Food & Drug Administration. FDA-Recognized Antimicrobial Susceptibility test Interpretive Criteria. Available from: https://adoptaware.org/assets/pdf/aware_policy_brief.pdf. [Last accessed on 2019 Sep 03].
Mitsakakis K, Kaman WE, Elshout G, Specht M, Hays JP. Challenges in identifying antibiotic resistance targets for point-of-care diagnostics in general practice. Future Microbiol 2018;13:1157-64.
Reali S, Najib EY, Balázs KE, Tan AC, Váradi L, Hibbs DE, et al. Novel diagnostics for point-of-care bacterial detection and identification. RSC Advances 2019;9:21486-97.
Banerjee R, Özenci V, Patel R. Individualized approaches are needed for optimized blood cultures. Clin Infect Dis 2016;63:1332-9.
Centres for Disease Control and Prevention. Antibiotic Prescribing and use. Be Antibiotic Aware. Available from: https://www.cdc.gov/antibiotic-use/index.html. [Last accessed on 2019 Oct 20].
World Health Organization. Aware Portal. Available from: https://adoptaware.org [Last accessed on 2019 Sep 20].
World Health Organization. WHO Report on Surveillance of Antibiotic Consumption: 2016-2018 early Implementations. Available from: https://www.who.int/medicines/areas/rational_use/oms-amr-amc-report-2016-2018/en/. [Last accessed 2019 Sep 20].
Hsia Y, Sharland M, Jackson C, Wong IC, Magrini N, Bielicki JA. Consumption of oral antibiotic formulations for young children according to the WHO access, watch, reserve (AWaRe) antibiotic groups: An analysis of sales data from 70 middle-income and high-income countries. Lancet Infect Dis 2019;19:67-75.
McGettigan P, Roderick P, Kadam A, Pollock AM. Access, watch, and reserve antibiotics in India: Challenges for WHO stewardship. Lancet Glob Health 2017;5:e1075-6.
Kalaiselvan V, Thota P, Singh GN. Pharmacovigilance programme of India: Recent developments and future perspectives. Indian J Pharmacol 2016;48:624-8.
Gandra S, Mojica N, Klein EY, Ashok A, Nerurkar V, Kumari M, et al. Trends in antibiotic resistance among major bacterial pathogens isolated from blood cultures tested at a large private laboratory network in India, 2008-2014. Int J Infect Dis 2016;50:75-82.
Cassir N, Rolain JM, Brouqui P. A new strategy to fight antimicrobial resistance: The revival of old antibiotics. Front Microbiol 2014;5:551.
Kotwani A, Holloway K. Access to antibiotics in New Delhi, India: Implications for antibiotic policy. J Pharm Policy Pract 2013;6:6.
1 Pharmacovigilance network as an additional tool for the surveillance of antimicrobial resistance
Jean Marie Vianney Habarugira, Albert Figueras
Pharmacoepidemiology and Drug Safety. 2021; 30(8): 1123


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Riding the Bullet: The Deluxe Special Edition Double
Thread: Riding the Bullet: The Deluxe Special Edition Double
by Stephen King and Mick Garris
Featuring the complete original novella and screenplay; great artwork by Bernie Wrightson; a unique design with two color printing throughout; color wrap-around cover artwork and color interiors by Alan M. Clark
Plus: Exclusive storyboards, photos from the set, production notes, hand-corrected script pages, and more from the Top Secret "Director's Notebook" kept during the production
Status: Collector's Gift Edition Available Now!
ISBN-13: 978-0-9840745-0-1
ISBN-10: 0-9840745-0-3
Riding the Bullet by Stephen King has been described as a "ghost story in the grand manner" and the story of "a young man who hitches a ride with a driver from the other side," but in this special edition only available from Lonely Road Books, we're going to show you King's classic novella in a way you've never seen it before: alongside the feature film screenplay adaptation by director Mick Garris.
The road from print to the silver screen is often a bumpy one and much has been written about how a story is sometimes transformed to make it work in moving pictures. This is your chance to experience Riding the Bullet in a way only those close to the production of the film ever have. Start with King's original novella, then flip the book over and read the original script by Mick Garris. Compare what he kept, what he had to change, and even the storytelling flourishes he added to round out the tale.
This highly collectible special edition was published in the same manner as our acclaimed edition of The Arthur Darknell Double — in the tradition of the old Ace Doubles. This is the very first Stephen King Limited Edition to be published in this manner, and it was a huge hit with the collectors.
Complete with stunning cover artwork by Alan M. Clark and beautiful interior artwork by Bernie Wrightson, this exclusive Lonely Road Books special edition was one of the most discussed small press books of the year.
About this Special Edition:
With an oversized trim size, two color printing throughout, and an extremely low print run, Riding the Bullet by Stephen King and Mick Garris was designed with the ultimate collectors in mind. Each edition featured a deluxe binding selected from the finest materials available. Like the previous Lonely Road Books releases, all of the signed copies were reserved within a week of bring announced, so the Collector's Gift Edition is the only remaining edition available!
Limitation Information:
• Collector's Gift Edition: limited to just 3000 copies bound in a deluxe material and housed in a special slipcase ($75)
• Limited Edition: 500 deluxe copies signed by Mick Garris and Alan M. Clark on a specially illustrated signature page, featuring the complete text of the Collector's Gift Edition but bound in a different deluxe material and housed in a custom-made traycase ($250)
• Lettered Edition: 52 deluxe copies signed by Mick Garris, Stephen King, and Alan M. Clark on a specially illustrated signature page; with all the special features of the Limited Edition, plus a different type of high quality binding and a satin ribbon page marker; all housed in a custom hand-made deluxe traycase ($750)
This is my only Lonely Road title so far. I love the concept of the 'double' as well as the extra content included in this book. Combine the great production values and the extra content make this a very nice addition to my collection. Looking forward to adding more Lonely Road titles to my shelves in the future.
frik51
Senior Member Starting to Drool Incessantly
I really like this book and was happy to be able to collect all three states.
The lettered is a PC copy though....
theenormityofitall
North Aurora, IL
I have the limited edition only....not a bad book, but not one of King's best either.
I have a couple other Lonley Roads books also but the titles escape me at the moment.
I was pretty happy with the Limited Edition. Great production values, imo.
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Give me a book set in/about Italy and I'll love you until the end of time. PLUS... road trips and swoons. I can't wait for this one!
As if the title weren't enough to make you squeal with delight, the heroine loves YA books so much that she goes to them for love life advice. Who hasn't done that?
This book just sounds so interesting. I can't wait to get my hands on it!
I cannot resist a tale about assassin families combined with a fantasy setting.
Literacy is a capital offense. I just need this because it sounds epic and oppression and rebels!
Jane Austen meets X-men. I really need no other reason than this.
It has people magically jumping to libraries in it! I will read this!
TELL US THE DEBUTS YOU ARE LOOKING FORWARD TO!
Oh! And while you're here... You should totally sign up to participate in Jana's (That Artsy Reader Girl) 2016 Debut Author Challenge! If you're excited about 2016 debuts, this is the perfect reading challenge for you! There's author interviews, author and publisher-sponsored giveaways, and monthly swag pack giveaways to participating reviewers! Read about the challenge and sign up by clicking on the button below!
Bookishly Ever After sounds adorable!
So many great books in 2016 debuting this was a hard category to narrow down! I love your list and some of these made it to mine, although I wish I had added Burning Glass!!!
Bookishly Ever After almost made my list, but I tweaked mine a bit to add some non-fiction in that I am eager to read.
Four of these are on my list, and one almost made it. I am excited for time travel books in 2016.
I've seen a lot of these covers on goodreads! I put these Vicious Masks on my TTT, too!
A lot of these are new to me and sound great! I am especially eager to read Thief of Lies and Into the Dim.
OOh nice! I have my eye on a few of these as well!
Aw Love & Gelato sounds so cute. I love a good road trip story too.
I like the list. I have Blackhearts, Assassin's Heart, These Vicious Masks, and Burning Glass on my own list. I haven't heard of many of the others yet but the covers look appealing!
I was eyeing Bookishly Ever After. I don't read a lot of YA contemporary, but I love the synopsis.
Quite a few of these made my list as well today! I'm especially excited for Blackhearts and Burning Glass! Awesome list!
Awesome list!! We have several books in common this week. I also considered adding Bookishly Ever After, but I ran out of spots.
I see some of the same books from my list and some more I need to add to my TBR list. Man it just keeps growing!!!
Blackhearts SO MUCH YES. Give me pirates ANY day. Also the Vicious Masks. I love the running theme of literacy and bookish geekness in so many of the early 2016 releases!
GIMME ALL! I can't wait for 2016! Just looking at this makes me excited!
I have at least half of these on my list too: Blackhearts, Into the Dim, Bookishly Ever After, Assassin's Heart, Sword and Verse. And the others are 99% that are on my GR list for next year's tbr!
<33333 i love ALL of these and have them on my TBR!
i am also excited for CARAVAL by Stephanie Garber, IVORY AND BONE by Julie Eshbaugh, A SHADOW BRIGHT AND BURNING by Jessica Clueless and THE READER by Traci Chee.


As many of you know, I am trying to find more natural, safe products for our family to use. It is difficult these days to research everything and try to find what is best. I know that many of my friends have switched their bottles to either glass or other safe plastics that are BPA-free (like Born Free). Sunscreen has been a big issue for me this summer since Asher's skin seems a little more sensitive and many of the brands have some harsh chemicals in them. Our doctor recommended Blue Lizard, which I have been using. I had not researched it until recently and found it to be a safe sunscreen on average but has a higher health risk than others on the market. Here is a list of safer baby sunscreens: Jason's Sunbrella's Minerals, California Baby SPF 30, and TruKid Sunny Days Everyday Mineral Sunscreen. One of the mom's in our playgroup recommended this website: http://safemama.com/ . They are known for their "one-stop child safety, product-recall, well-being, eco-conscience resource for parents." They have new information everyday that is very helpful. Today's post stated that Pyrex lids are BPA-free...very helpfuul information. So if you are needing some help on certain products and don't have time to call the manufacturer, you should check this website out!
That has been a big issue for us too this summer. I was mostly worried about the estrogens found in all of the popular brands of sunscreens, which have been shown to cause gender-bending problems in some of the test animals. We switched to California Baby sunscreen. It seems to work great on Radnor, but I had one day when it didn't really work that well on me.


It was a normal day like any other in February. The air was crisp, with a warm breeze. Today's journey had me feeling adventurous. As I did not want to stick to the monotony of the Santa Clarita bike paths. Don't get me wrong, 40 miles of paved paths are great..... If you have a beach cruiser and are retired.
So I loaded Sadie up on my Ford (Sadie is my 2013 Giant TCR Advanced) and we headed North. Not knowing what to expect, I hit the I-5 freeway and started rocking out to some KROQ alternative music.
I found myself in a small town called "Lake of the Woods", that is dauntingly recognizable to that of any horror movie. As I laced up my Giro's and waited for my Garmin to lock in on it's GPS, I looked around at the small run down town, with very little activity and started to pedal West. I was fighting one of that nastiest headwinds known to man as I gradually started to climb. It was one of those rides that since I didn't know where I was going, and the wind was so brutal, I almost called it quits. Then I saw what seemed to be deserted mountain road climb, sheltered with the help of lush green Christmas trees, which gave me the strength to pedal on. The climbing grade bounced around quite a bit, and the 9% grades seemed to feel pretty flat. I was hooked.
I was cycling through Fraizer Park, just North of Los Angeles into Mount Pinos, and it was absolutely breathtaking. It was a fairly mild day, with remnants of the winters snow. I was surprised that there was still this much snow just an hour North of LAX. Being from Canada, it was welcoming reminder of the Motherland. The climb was a beautiful reminder that California isn't always the Hustle and Bustle we've come to expect. During the descent, I had even topped out at my max speed.
The ride was great. It was only 22.5 miles, but I climbed over 2,700 feet. That's not bad when you consider half the ride is back down.


Surgeons conducting clinical trials to test a Medtronic Inc bone-growth protein used in spine surgery, some of whom got at least $62 million from the company, failed to report serious complications in their research papers, the Wall Street Journal reported.
Fifteen of the surgeons got at least $62 million from the company over the past decade, the paper said, citing an analysis of Medtronic documents and disclosures on the company's website.
These complications weren't reported in research papers the surgeons wrote on those trials, even though the papers were peer-reviewed, the study said.
In a statement, Omar Ishrak, Medtronic's chief executive, on Tuesday said the Spine Journal study does not raise questions about the data Medtronic submitted to the FDA in the approval process.
"Based on that data, we strongly believe that the safety profile reported to the FDA and summarized in the product label support the safe use of rhBMP-2 for the identified indications," he said. The company will continue to investigate questions surrounding researchers' potential conflicts of interest and refine policies as needed, he said.


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We believe that the Godhead eternally exists in three persons: Father, Son and Holy Ghost, and that these three are one God.
We believe that the Church consists of all persons who have been regenerated by the Holy Ghost and made new creatures in Christ Jesus.
We believe that all have sinned and come short of the Glory of God and that through the death and risen power of Christ, all who believe can be saved from the penalty and power of sin.
We believe that our Lord Jesus Christ is the Healer of the body and that all who will walk in obedience to His will can claim Divine Healing for their bodies.
We believe that our Lord Jesus Christ baptizes in the Holy Ghost and that this Baptism with signs following is promised to every believer.
We believe that the Lord Jesus Christ will receive unto himself the Church and afterwards set up His Throne as King.
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We believe that the Church should claim and manifest the nine gifts of the Holy Spirit: Wisdom, Knowledge, Faith, Healing, Miracles, Prophecy, Discernment, Tongues and Interpretation.
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text:
Despite being called to boycott, Nike shoes are still sold out in China
April 1, 2021 electrodealpro
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A wide range of Nike products with special offers have been sold out on Chinese e-commerce platforms, despite the brand being called for a boycott in connection with the cotton origin controversy. Xinjiang.
The limited edition Air Jordan 4 sneaker was immediately out of stock on Tmall.com on Thursday (March 25), while the Nike Dunk Low shoes were also sold out on Jingdong (JD.com) immediately. after they hit shelves during a hot sale on Friday (March 26), as reported by HK01.
The latest pair of female Nike shoes reduced to 699 yuan ($ 107) on the online store in Tmall attracted 350,000 subscribers and sold out immediately.
The above phenomenon has caused Chinese netizens to have mixed opinions. Many of these, which are calling for a boycott of brands that refuse to produce Xinjiang cotton on suspicions of forced labor involving Uighur workers, have criticized the purchase as "hypocritical". while others argue that it is a bargain that cannot be ignored.
H&M, Nike, Adidas and Burberry are among the fashion brands influenced by the extreme nationalism movement in China. In which, H&M suffered the most heavy losses.
For other brands, the boycott did not affect their sales in China. As of Monday, brands can still be found on major Chinese e-commerce platforms such as Taobao, JD.com and Pinduoduo, and consumer demand remains high.
The Chinese Basketball Association (CBA) and the Chinese Football Association (CFA) are still silent on this issue. Nike is the CFA's largest sponsor with a 10-year contract worth 3 billion yuan ($ 458 million) in 2018. Nike's significant influence in China is said to have protected the brand from backlash, according to the CNA news agency.
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Buzzr has an answer for viewer retention
Tiny Riot! chief Gayle Gilman explains how the digital studio is scoring with YouTube versions of Family Feud, Password and Body Language.
Viewer retention is a key factor in the YouTube algorithm that calculates search discovery and ad revenue. So when Gayle Gilman, chief of FremantleMedia North America's digital studio Tiny Riot!, saw that the initial episodes of its revivals of Family Feud, Password and Body Language on its YouTube game show channel Buzzr were seeing a 70% retention on episodes ranging from eight to 18 minutes – an eternity in the online video space – she was as jazzed as a contestant who just aced the lightning round.
"That kind of retention is insane for YouTube," says Gilman, EVP of digital content for FremantleMedia North America. "In fact, when we first shared those numbers with (YouTube execs), they were like, 'I can't believe it.' They want people watching longer. And people are watching three episodes in a session." (YouTube does not release overall audience retention averages.)
Gilman has a theory why Buzzr is scoring such high retention rates.
"You can't do a cute pet video that's 18 minutes, but when you have game play, people want to watch to the end and see who's going to win," she says.
Gilman spent two seasons in Alaska riding around in big rigs as the show runner on Ice Road Truckers, produced by Thom Beers. When Beers – who was appointed CEO of FremantleMedia North America in 2013 – brought her on board to launch Tiny Riot! a year and a half ago, she searched the company's vast catalog of IP – which contains everything from competition shows such as American Idol to Bob Hope films like The Seven Little Foys and Son of Paleface – for low-hanging fruit that was ripe to be adapted for digital platforms.
It didn't take her long to uncover a mother lode of potential – 154 game shows formats, primarily from its acquisition of the Goodson-Todman Productions library, only four of which were being produced for television here in the U.S.
"I thought that was a really good opportunity, because was nobody was really reimagining game shows for the YouTube platform or the digital audience," Gilman says. "Then I came to YouTube and started having conversations with them, and they said, 'We've been dying to figure out how to break game shows (on the platform) for the last year.'"
So Tiny Riot! took up residence at YouTube Space LA in February and March to shoot new versions of Password, Family Feud and Body Language re-imagined for digital-natives, which started rolling out their first seasons last month.
Key to the conversion was choosing games that were simple enough to pull off without costly, complicated sets or big prizes – which is why the charades show Body Language, which had a two-season run in the mid-80s, got the nod instead of a more high profile property like The Price of Right.
Also vital was filling both the host and contestant slots with young digital influencers who would appeal to the 18 to 24 age demo. This meant that a very loose definition of the word "family" would need to be used for Family Feud, hosted by Adam Lustig (College Humor), which uses teams of three instead of the traditional five-person team on the TV version, which debuted in 1976.
"We have a team captain and they bring fellow YouTubers they've known or cross-promoted with," says Gilman of Feud. "We had a couple of people who brought their husband or wife who also had a channel or was participating in their channel, and somebody who brought their cousin. But mostly it's people who are working together. "
Password host Steve Zaragoza (SourceFed) says he didn't know what to expect when he auditioned for the show. He was unfamiliar with the original 1960s and 1970s incarnation of Password and its host, Allen Ludden, the late husband of actress Betty White. So he just did his thing, manically running around the set and interacting with audience members.
Gilman says there's a possibility that the online games shows could be repurposed for linear TV, including a potential programming block on Buzzr TV, a cable channel launching in June dedicated to vintage game shows from the FremantleMedia catalog.
In the meantime, Tiny Riot! is in pre-production on a version of Beat the Clock, which originally debuted on television in 1950, and developing three wholly original new game shows for YouTube.
Adam Lustig, Body Language, Family Feud, FremantleMedia North America, Gayle Gilman, Password, Steve Zaragoza, Thom Beers, Tiny Riot!, YouTube Space LA
Todd is StreamDaily's U.S. West Coast Correspondent. He has written for a wide range of publications, including The Hollywood Reporter, Variety, the Los Angeles Times, the New York Post, NylonGuys and, yes, even the Weekly World News. Earlier in his career, he served as senior editor for the pioneering alternative movie magazine Film Threat. You can reach him at toddrlongwell[at]gmail.com or on twitter @toddlongwell1
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