text:
Hotels' in-room movie selections should not include porn, according to two religious scholars.
Strange religious bedfellows unite for letter against hotel porn
By Dan Merica, CNN
(CNN) – A letter penned by two notable scholars - a Christian and a Muslim - and sent to a number of different hotel industry executives has asked those hotels to remove pornography from their company's in-room movie selections.
Robert P. George, a professor at Princeton University and the past chairman of the conservative National Organization for Marriage, and Shaykh Hamza Yusuf, co-founder of Zaytuna College, a Muslim school, wrote the letter to urge hotels "to do what is right as a matter of conscience."
"We are, respectively, a Christian and a Muslim, but we appeal to you not on the basis of truths revealed in our scriptures but on the basis of a commitment that should be shared by all people of reason and goodwill: a commitment to human dignity and the common good," reads the letter.
The letter marks the joining of two unique men with two distinctly different faiths. Yusuf says they were able to put aside their disagreement on other issues because of their commitment to this cause. "We need to see that those things that are threatening our society today are much graver than anything that may divide us," he told CNN.
CNN's Belief Blog: the faith angles behind the big stories
Reaction to the letter from some adult film stars - and even from some advocates for removing porn from hotels - was negative.
Craig Gross, a pastor and the founder of XXXchurch.com, says the letter is an empty gesture with no power behind it.
"It has got to be one of the dumbest letters I have ever read," Gross said. "It is like asking the Internet to stop selling porn. It sounds good and all, but it isn't going to happen."
But the letter's authors argue that the Internet and hotels are different, with hotel owners directly profiting off the temptation of porn.
"We urge you to do away with pornography in your hotels because it is morally wrong to seek to profit from the suffering, degradation, or corruption of others," states the letter. "You are placing temptation in their path - temptation for the sake of profit. That is unjust. Moreover, the fact that something is chosen freely does not make it right."
Yusuf continued to use this argument in an interview with CNN. "Just because we are able to do something doesn't mean it is what we should be doing. And just because you can sell these things doesn't mean it is something you should be selling," he said.
In Gross' opinion, this logic is a slippery slope. When planes offer access to WiFi, is that placing temptation in the path of those who may view porn on the Web? When hotels offer room service, he asks, are they tempting dieters?
Gross has a long history of helping those with porn addictions, and his website is dedicated to getting people help. According to him, removing porn from hotels is a futile endeavor because of the "unfettered availability of porn on the Web. "
According to a 2005 report on the state of the adult entertainment by Adult Video News, a trade journal on the adult-film industry, 55% of hotel movie rentals are porn movie rentals. The average revenue from movie rentals, according to LodgeNet, a company that provides in-room entertainment services, was $16.51 per room per month in 2008. In the third quarter of 2009, LodgeNet brought in $64.8 million. This, however, included more family-friendly options as well.
A 2011 report by Robert Mandelbaum at Colliers PKF Hospitality Research found that from 2000 to 2009, movie rental revenue for hotels in general decreased 39%.
Even with the reported slip, Gross and other critics acknowledged there is a demand for adult entertainment.
"This is supply and demand," Gross said. "We spin our wheels doing all the wrong things. The issue is not that it is available; the issue is that people buy it."
Prior to this letter, however, some hotels had already pledged to remove pornography from their programming or had removed it.
In 2011, Marriott International - a company founded by a member of The Church of Jesus Christ of Latter-day Saints that continues deep Mormon ties - pledged to phase out adult content from all hotel rooms. The move came after groups like Focus on the Family met with Marriott officials to urge them to remove adult movies.
The church of porn and football
"Adult content will be off the menu for virtually all of our newly built hotels," read the Marriott statement. "Over the next few years, this will be the policy across our system."
Marriott is not the first hotel group to do this, though. Omni Hotels, a Dallas-based luxury hotel chain, removed all adult films from its in-room systems in 1999. According to other reports, adult-free programming is helping the Omni differentiate itself in the hotel market.
Websites like cleanhotels.com look to help porn-free hotels by compiling a list of hotels that do not offer adult entertainment and leading people to them. Cleanhotels.com says it does so because its supporters want to know they are "supporting a facility that cares enough about the wellbeing of its customers not to make harmful pornographic movies available."
The American Hotel & Lodging Association, however, defends the right of hotels to choose what services to offer in their rooms.
"In-room offerings such as this are made available based on market demand, are not offered in all hotels, and are subject to the same legal review all hotel operations are subject to," read a statement from Kathryn Potter, senior vice president of marketing and communications for the association.
Ron Jeremy, an adult-film star who has been in over 2,000 porn films, according to the Internet Adult Film Database, sees efforts to remove porn from hotels as attacks on freedom of speech.
"What they have to understand is that freedom of speech works for all of us, not just for them," Jeremy said about those who want to get porn out of hotel rooms. "This is a country that is secular; you have freedom from religion and freedom of religion. Give me a break."
While Jeremy said he is all for making sure kids in hotel rooms can't get to porn - "I think that is marvelous" - he said he doesn't see why adults shouldn't watch "consenting adults have consenting sex."
"If a guy has a hard day at work or is at a convention and wants to sit down in his hotel room and puts on an adult film and plays spank the monkey, why can't he do that?"
Filed under: Christianity • Islam
Next entry »Belief Blog's Morning Speed Read for Friday, July 13
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http://www.youtube.com/watch?v=n0Uml_sNBLU
July 12, 2012 at 9:34 pm |
Atheism is not healthy for children and other living things
Prayer changes things
http://www.youtube.com/watch?v=6sYCFbBDe8w&feature=related
Bootyfunk
actions cause change; prayer wastes valuable time.
Kegan
Yes prayer does change things.
This girl was alive and then prayer killed her.
July 12, 2012 at 10:11 pm |
שמיחזה
hah hahahahah
one for (Magic) non for prayer
by magic i mean using that strange talking stone and pressing the 9 1 1 glyphs in those order then communicating with the spirits in the stone to summon a mystical white chariot that will escort your daughter to a magical realm of healing called the Hoss-Peetal were she will be giving the magical elixir of In so-lian
seriously western-modern-medicine can trace its roots back to the Craft the magic art called apothecary that was called witch craft by the church ,... thanks Pagans
now the Magical Talking Stone that's still a mystery to me?????
What's a brony?
Why do atheists consider Hitler a "Christian" even tho Jesus himself was a Jew? Jesus never EVER preached violence towards Jews or any other.How could believe all these lies?
So much for being so educated in Christianity.Jesus knew the Jews would have him kill,what did Jesus do?
Atheists if you wish to bash Christianity for what people have done,I can bash atheism for what Mao and Stalin did.
This is incorrect because atheists do not have any sort of cohesive behavior, they do not stand for any sort of platform and so on. Bashing atheists is like bashing people who don't play golf, you are hitting so many different random variables. Atheists are not a single united group that adopts many similar traits like religion. They are only united by not following one thing. Making talking about atheists as a group pointless.....actions committed by atheists do not reflect on other atheists because they are not a group.
Every religious person is not the same.
So what your saying is,I'm held accountable for someone elses actions even if they live on the other side of the planet?
Even if I have not committed the action nor have I ever met the person?
Gee atheists do have "logic" that makes them soooooo smart..lies.All lies.
hawaiiguest
And the only way to know what they are is what they profess to be. If Hitler stated that he was a Christian, then no one other than he is in a position to say otherwise. What if he had some kind of revelation that led him to his actions? Here's what you're not getting brony, it's not so much the actions that are important when it comes to this conversation, it's the reasons behind it. The Nazi regime was well known as being highly religious, and yes, Stalin and Mao were atheists, but they did not do what they did in the name of atheism.
@brony
"So what your saying is,I'm held accountable for someone elses actions even if they live on the other side of the planet?"
What is ironic here is that your religion promotes the idea that you are held responsible for what Adam did (original sin), and even in the 10 comandments, any person that didn't believe in god, the family would be cursed for 4 generations.
Dude, do you know anything about history? The Catholic Church was heavily anti-semitic at the time and even supported Hitler in a number of ways. Being a Christian does not exempt you from hating Jews.
As for the difference between Christian leaders who commit atrocities and atheist ones who do, you can make that comparison when an atheist leader says "Because I'm an atheist, I am compelled to do this and that. Because there's no god, we have to kill all these people." Because when I talk about Christian atrocities, I'm talking about leaders who regularly said "God told me this war is His will and He supports me" and "as a Christian, I am compelled to kill those who don't accept Christ."
Check out Hitler's speeches. How many times does he reference God and Christianity? A lot. How often do Mao or Stalin reference "no god" as a reason to kill? I've yet to see one instance.
I'm not a GOPer, nor do I play one on TV
@brony,
Because Adolf Hitler was a Roman Catholic, born and baptised in Austria. While he stopped taking the sacraments after his childhood and clearly he did not live his adult life according to what we would deem 'Christian values' he made speeches affirming Christianity and opposed atheists.
Speech at Koblenz, 1934:
"National Socialism neither opposes the Church nor is it anti-religious, but on the contrary, it stands on the ground of a real Christianity. The Church's interests cannot fail to coincide with ours alike in our fight against the symptoms of degeneracy in the world of today, in our fight against the Bolshevist culture, against an atheistic movement, ... These are not anti-Christian, these are Christian principles."
You can find this reference (and many others) here:
http://en.wikipedia.org/wiki/Adolf_Hitler%27s_religious_views
Whether he truly believed in a Christian God or not is moot. He motivated the German people using Christian rhetoric as his ally.
"Jesus never EVER preached violence towards Jews or any other"
"Do not think that I came to bring peace on Earth; I did not come to bring peace, but a sword. For I came to set a man against his father, and a daughter against her mother, and a daughter-in-law against her mother-in-law; and a man's enemies will be the members of his household. He who loves father or mother more than Me is not worthy of Me; and he who loves son or daughter more than Me is not worthy of Me. And he who does not take his cross and follow Me is not worthy of Me. He who has found his life will lose it, and he who has lost his life for My sake will find it." (Matthew 10:34-39 NASB)
sounds like jesus is saying he is not coming back for peace, but for war.
wow i guess he had nothing but love for the pharisees,...
Professor Kill-Joy and Shaykh Buzz-Kill
We believe in ghosts,
and we have boring sex lives.
Everybody else should be like us!
Religion is sooooooo awesome!
FRIDAY THE 13TH !!!!
OUCH !!!! OUCH !!!! OUCH !!!!
BAD FOR MANY !!!!
masterdavid
Heavensent. You my dear are beyond brainwashed. It gushes from your every statement. Please seek education and better yourself for the betterment of the species
2LiveJew
Darn good thing I don't have 24/7 access to naughty sites with my smart phone now. I was spending a FORTUNE on hotel rooms just trying to get my fix...
YOU GOTTA LOVE JESUS!!
http://www.youtube.com/watch?v=lThuhz45pDI&feature=plcp
Cyn507
I do not want any religious leaders deciding what is or isnt ok for me to view. It isnt their decision. I dont need their morals inflicted upon me. I have a brain and will decide for myself what i choose to view or not. Get lost!
MY RESPONSE TO THIS IS DESERVING AT BEST!
http://www.youtube.com/watch?v=gPDirIhy5Zs
Voice of Reason
Come on bro, keep the bandwidth down!
LittleHero
If you are a "seeker" and feel the need for a spiritual experience – I would suggest you attend a Unitarian service. All are welcome, in fact atheist are welcome as well. In all my years as a closet atheist (since about 7 or 8), I was awe struck that one of the only places I've felt comfortable telling strangers that I am an atheist was in a church. I love one of their slogans – No hell for over 150 years.
For those of you that do not want to live in our secular society, I know of several Amish communities in Wisconsin. It's real fun in the winter with 6 hours of daylight and temps below zero. Chopping wood by hand is alot of fun, and you better have some canning skills and like working like a dog all summer long in order to keep from starving and freezing the rest of the year.
Mass Debater
"In all my years as a closet atheist (since about 7 or 8)" I call BS
Santa = not real
God = not real
Adults lie – even if they believe it themselves.
AND YOU MEAN TO SAY?
http://www.youtube.com/watch?v=VUMfDOLA1G8
p**0*r*n is defined as:
television programs, books, etc., regarded as catering to a voy*euris*tic or obse*ssive interest in a specified subject...
According to this we could call the bible, god and religion a form of p**0*r*n,right?
Voice of reason, is your post what Christians can expect from an aging 75 y.o. atheist, Cough!
If so, it proves how lost you stay, as you age,
@HeavenSent
The only thing an aging christian can expect is that they are all going to die just like the rest of us and it will stop there, nothing more.
Voice of unreason, I wished I copied and saved the post of a Christian that posted a year 1/2 ago ... he wrote something along this line ... When an atheist dies, they get all dressed up, with no where to go.
No one is going anywhere once they die. You have no proof but you do have the burden to prove it.
Holy crap, HS, how much stuff DO you copy and save in your digital war on the unholy? Does the inside of your computer look as scary as your trailer?
OTOH
HeavenSent: " I wished I copied and saved the post of a Christian that posted a year 1/2 ago ... he wrote something along this line ... When an atheist dies, they get all dressed up, with no where to go."
1. Do you mean you wish you would have copied it. Remember, it's "I wish I were an Oscar Meyer wiener"... not "I wished I was..."
2. "All dressed up and nowhere to go" describes Christians in their coffins too.
atheism does not benifit mankind at all.
atheism does not harm mankind at all.
Can religion say that?
faith cannot harm a person at all.
Can atheism say that?
The facts do not agree with your opinion. You should be thankful for the many atheists who have made many great scientific and medical discoveries that have saved lives and made this world a better place.
@What's a brony?
Oh yes faith doesn't hurt people. Children dying from faith healing cr.ap, parents sli.tting their childrens throats because they have faith that the world will end soon. Wars started because of a difference in faith. Shall I go on?
Ask the people that died in the name of their faith. Hitler was a Christian and had his faith...how did that little story end. Faith in imaginary things and following people in the name of it can be quite harmful.
Alpa Chino
Yeah...doesn't 'benifit' anything. But does benefit many things.
Hitler was for from a Christian.Jesus not once ever preached violence towards the Jews.Nothing in the bible supported HIS own ideas.
Do you consider Stalin an atheist even tho he considered himself one?
You think like that to attack the "Theist" for something they themselves never did.
You should be ashamed of yourself.
•far from
Nice no true scotsman fallacy. Here's the point that your "conveniently" avoiding. Faith has, does, and will harm people, and it doesn't matter whether YOU think that they have the "right" faith, what matters is that they had religious faith, and it was directly linked to them harming themselves, or others.
Of course atheists harm us. What? Do you believe we want enemies of God walking among us?
Alpa Chino, you posted "Yeah...doesn't 'benifit' anything. But does benefit many things."
Answer: You're taking over Tommie Tom's obsession of assuming she needs to make corrections. No one can be that obsessive, unless, this is JUST another phony dummy handle. LOL.
HeavenSent, nobody anywhere is like me. Don't you worry your head, girl.
just sayin, stop lying. Hitler was not a Christian, no matter how much you atheists want to re-write history.
I'll say one thing about HS – he shows how Hubbard did it.
Hitler was a christian. Just because you don't like his record now, doesn't mean you get to kick him out of your club after the fact. Too late.
Hitler was as much a Christian as HS is and thats a fact. He was raised as a Catholic, baptized a Catholic, confirmed a Catholic, claimed to be Catholic and made his cabinet and soldiers swear allegience to him and God on a bible and promoted Catholicism among his ranks. He certainly isn't going to any cloudy heaven, but then again, neither is HS...
You're getting the crap beat out of you and rightfully so!
MANKIND IN THE ANIMAL KINGDOM:
http://www.youtube.com/watch?v=lZaNZ-jlZ-w
MMarkle
Religion has caused more harm to human beings than just about anything else. Most wars in history have a religious or faith motivator. The Crusades, which changed the middle east from a center of knowledge in the old world to what we know it to be today, was about religion. All the terrorist running around have a religious motivation, or at least use it as an excuse to do what they do. Hitler was indeed a Christian. The truth of the matter is that IS the history of the organization you follow like an idiot. You are one of the members of their base of power. They profess that they have actual "faith" like you do, but more likely they just like being in charge of legions of people that follow orders and don't ask a lot of questions. They do not drink their own proverbial cool-aid and are smart enough to manipulate you, which seems to contradict the lack of intelligence required to have your kind of blind faith. Granted, many intelligent people do proclaim some kind of idea that there is a lot more going on than we can perceive, but they do not have the audacity to claim they know the will or word of "God". Only a fool would be so arrogant.
Now atheists...who have they harmed? Ever? Have they ever started a war against people that do not agree with them? Ever tortured anyone until they agreed? Find an example from an actual history book and show me how atheism has caused such things?
Ain't it funny how Christians want to be in everyone's drawers...
A CHRISTIAN
Certainly not your drawers for sure Denise! Were you born beyond repair Denise?
Gecul
Well, "christain" maybe you should get a look at Denise before you slam her. I'd guess you are the one needing repair!
Apatheist
Denise is smoking hot man, I don't know what you're talking about...
Always_Amused
Well "A so-called CHRISTIAN" what makes you think Denise NEEDS repairing? Denise is not the one sticking her nose into other people private business, is she? I do not know anything more about Denise than YOU do, but I DO NOT have any reason to think that Denise is BROKEN! Perhaps it is YOU that is broken, hmm?
How about a damp mormon diaper?
Stephen Prothero
I'd do her.
Who cares? I get mine off the internet. The one thing I despise is religious freaks meddling with my life, my rights and my privacy. Besides, I keep the paper cup and the tissue industry in business, helping the economy.
Why can't religious people just preach to their own religion's followers and leave everyone else alone? This world has already proven since the Crusades that religion does no good when you force it on people. Most people do not have any problems with anyone who chooses to practice a religion. The problem ALWAYS comes in when the religious person wants to force others to follow their ways. God gave us free will and religious people are trying to take it from us. Hypocrites.
gods are gay
Dear Robert P. George and Shaykh Hamza Yusuf:
Please die of rampant cancer.
And I believed I would have a who posting time without hearing or seeing "GAY"
I heard a who.
Notice the guy in the pic is alone ( no woman ) Ill bet he has an alter-boy in the closet
Ummm, yes?
I think the point is that he is alone – which is the most common p0rn watching scenario.
I think the point is on your head! Ha! I crack myself up!
KyleGlobal
If you don't want to watch it; don't watch it. Quit trying to Talibanize the United States.
My biggest concern is, who actually pays for adult films at hotels? If you have an internet connection, you can satisfy your needs for free...
Or, here's an original idea, skip the internet entirely and get a real woman! Hell, hotels have been my favorite hangout for years. I've never even paid for a room! Not once!
phearis
Here's an interesting idea .... Hey Churches ... G T F O of my bedroom. 😀


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text:
Q: how to disable a row of listview in android? I have a ListView, each row of it is made up of a TextView and a Button.
When clicking the button, an alert dialog is displayed asking "are you sure you want to disable this item?", and If someone select the button "Yes", the TextView and the Button will be disabled.
My code is as above. As a result, the TextView and the Button are properly disabled, but when I scroll down and up the ListView, these items will be enabled again.
How could I solve this problem?
Here is my code:
private class QuestionAdapter extends ArrayAdapter<String> {
    public QuestionAdapter(Context context, int resource, int textViewResourceId, String[] strings) {
        super(context, resource, textViewResourceId, strings);
    }

    @SuppressLint("ViewHolder") @Override
    public View getView(int position, View convertView, ViewGroup parent) {
        LayoutInflater inflater = (LayoutInflater) getSystemService(Context.LAYOUT_INFLATER_SERVICE);
        final View row = inflater.inflate(R.layout.list_layout_edit_sample_question, parent, false);

        TextView txt_question = (TextView) row.findViewById(R.id.txt_question);
        txt_question.setText(qText[position]);

        final int pos = position;

        Button btn_delete = (Button) row.findViewById(R.id.btn_delete);
        btn_delete.setOnClickListener(new OnClickListener() {
            @Override
            public void onClick(View arg0) {
                DeleteDialog(context, pos, row);
            }
        });

        return row;
    }
}

private void DeleteDialog(final Context context, final int pos, final View row) {
    AlertDialog.Builder alertDialog = new AlertDialog.Builder(context);
    alertDialog.setMessage("are you sure you want to disable this item?");

    // Setting Positive "Yes" Button
    alertDialog.setPositiveButton("Yes", new DialogInterface.OnClickListener() {
        public void onClick(DialogInterface dialog, int which) {
            ((TextView) row.findViewById(R.id.txt_question)).setEnabled(false);
            ((Button) row.findViewById(R.id.btn_delete)).setEnabled(false);
        }
    });

    // Setting Negative "NO" Button
    alertDialog.setNegativeButton("No", new DialogInterface.OnClickListener() {
        public void onClick(DialogInterface dialog, int which) {
            dialog.cancel();
        }
    });

    // Showing Alert Message
    alertDialog.show();
}

A: Use ViewHolder.
static class ViewHolder {
TextView textview;
Button button;
boolean disabled;
}

In your array adapter
@Override
public View getView(int position, View convertView, ViewGroup parent) {

    ViewHolder holder;

    if (convertView == null) {
        convertView = mInflater.inflate(<your layout id>, null);
        holder = new ViewHolder();
        TextView txt_question = (TextView) row.findViewById(R.id.txt_question);

       holder.textview = txt_question;
    final int pos = position;

    Button btn_delete = (Button) row.findViewById(R.id.btn_delete);

        holder.disabled = false;
        convertView.setTag(holder);
    }
    else {
        holder = (ViewHolder) convertView.getTag();
    }
    final View row = convertView;
    //Set views here
    holder.textview.setText(qText[position]);
     holder.button.setOnClickListener(new OnClickListener() {
        @Override
        public void onClick(View arg0) {

            DeleteDialog(context, pos, row);
        }
    });
    //Check for disabled
    if(disabled){
        //disable the views
    }
    else{
       //enable the views.
    }

    return convertView;
}

And set disabled in viewHolder here
private void DeleteDialog(final Context context, final int pos, final View row) {
AlertDialog.Builder alertDialog = new AlertDialog.Builder(context);
alertDialog.setMessage("are you sure you want to disable this item?");

// Setting Positive "Yes" Button
alertDialog.setPositiveButton("Yes", new DialogInterface.OnClickListener() {
    public void onClick(DialogInterface dialog, int which) {
        ViewHolder holder = (ViewHolder) row.getTag();
        holder.disabled = true;
        ((TextView) row.findViewById(R.id.txt_question)).setEnabled(false);
        ((Button) row.findViewById(R.id.btn_delete)).setEnabled(false);
    }
});

// Setting Negative "NO" Button
alertDialog.setNegativeButton("No", new DialogInterface.OnClickListener() {
    public void onClick(DialogInterface dialog, int which) {
        dialog.cancel();
    }
});

// Showing Alert Message
alertDialog.show();

}

A: You can simply use:

listview.getChildAt(childPosition).setEnabled(false);

Example:

if(listview.getChildAt(childPosition).isEnabled())
{
    listview.getChildAt(childPosition).setEnabled(false);
}

A: Take advantage of the isEnabled method of BaseAdapter. Override it and keep a boolean array for enabled indices.
boolean[] isEnabled; //initialize somewhere, everything to true

private class QuestionAdapter extends ArrayAdapter<String> {
    public QuestionAdapter(Context context, int resource, int textViewResourceId, String[] strings) {
        super(context, resource, textViewResourceId, strings);
    }

    @Override
    public boolean isEnabled(int position) {
        return isEnabled[position];
    }
}

private void DeleteDialog(final Context context, final int pos, final View row) {

    // Setting Positive "Yes" Button
    alertDialog.setPositiveButton("Yes", new DialogInterface.OnClickListener() {
        public void onClick(DialogInterface dialog, int which) {
            isEnabled[position] = false;
            questionAdapter.notifyDataSetChanged();
        }
    });

}

A: Actually your ListView every time inflates new view when you scroll it does not keep old views. You can solve this using holder pattern but the real issue will be still there which is related to your data binding technique.
Use some data Model(POJO) which should have state (enable/disable) and use that state to enable or disable your view. Update Model state from dialog and refresh your adapter by call notifydatasetchanged.

redpajama_set_name: RedPajamaStackExchange


TIGHAR ever searched for missing WASP pilot Gertrude Tompkins & plane?
Re: TIGHAR ever searched for missing WASP pilot Gertrude Tompkins & plane?
You need to provide us with your real name. Basic Forum rule.
I updated my profile; my apologies.
So has TIGHAR ever looked into searching for missing WASP pilot Gertrude Tompkins & plane?


east side bride: F* the $10,000 wedding. Have a picnic.
At the same time, some couples are counting every dollar and cent. Jessica (aka Budget Savvy Bride), who is aiming for a $10,000 wedding, is 10 weeks away from the big day, and the venue that told her she could bring her own wine now wants to charge $40/bottle. She hasn't signed a contract and she's afraid she might have to postpone the whole thing.
Meg told Jessica, "It's a wedding, not the event of a lifetime. You want to get married right? That's going to make you happy, right? So look around. Maybe you can have a wee adorable wedding in a friend's home, or a family house. Maybe a park. Maybe a courthouse with a sassy pencil skirt, heels, and a fabulous facinator..."
That's the best advice I've heard all year. Would you also tell these two, who are asking for donations to throw their $10,000 wedding?
*From hippie to Marxist in just five days. My Wesleyan is showing.
I just gasped at that wedding donation blog. Wow. Does that make me a snob?
No maggie that does not make you a snob.
I guess I'm in the minority here, but I support them. It's much better than going into debt and I'm sure there are many people out there willing to help them out. Why shouldn't they have the wedding of their dreams if they are willing to work for it?
It's this "wedding of your dreams" idea that is so corrosive, I think. Have an honest wedding, whatever that is. Small isn't bad, just like bigger isn't horrible. Start your marriage on a realistic footing, whatever that is for you.
Eek. What is it about weddings that makes people forget that very simple lesson, "if you can't afford it, you can't have it"?
An honest wedding... now, that's more like it.
I need to visit your blog more. For a variety of reasons.
We`re planning our wedding on a $4,000 budget. I don`t think this makes me better than you, or that other couple having their wedding at the Casa Loma (no joke, it`s this lovely castle in Toronto that books weddings 7 years in advance). I just want an honest wedding, like Meg said, and one that won`t make me go broke. Completely.
Barbecue wedding, and our own liquor license. Enough said!
Thank you. I know that I am getting closer and closer to having a wedding date in my future, and sometimes I look at everything and it just makes me tired and then I think. Tents, BBQ, kegs. Done.
I agree with Krista. I'm a public school teacher who is also getting married. I wouldn't dare ask for donations when I teach students who's families can barely afford to put food on the table. The wedding industry in America drives me insane. I wish people would learn to use their creativity and come up with a celebration that doesn't rely on "show".
Accidental Housewife, I agree on the "starting a life together" bit.
My parents are hosting a second reception for us in September, jointly with their 25th wedding anniversary. They are insisting that the invites be worded "celebrate the couple as they begin their new life together".
First off, ew. Gag me. Please.
Secondly, no, we've been living together for three years, which isn't ten, but it is enough to know that we have a life together, thank you very much.
As for donations, yeah, tacky. Honestly, it's a bit like having people pay for their own loot bags for a party, and then also bring a gift. The wedding industrial complex fascinates me at times.
Well, I know the couple in question, and their idea of the "wedding of their dreams" is eloping. But his mom is in her 80s and their friends are in the same boat--20s to 40's in a bad economy trying to find a happy medium.
I figure I could give my money to Starbucks or to my friends. Not so hard a decision.
With that said -- I guess I'm technically pro-donation, but I suppose I'm more anti-criticizing this decision. The dollars these two do (or do not) raise will be the measure of the popularity of their move; I daresay the majority of readers will not donate. The American Cancer Society receiving multiple thousands of dollars (or not) as a result of their efforts will speak volumes for the success of their campaign.
Furthermore, if what these two are guilty of is a lack of pride or an abundance of shame, I suppose we all have our moments in that category -- if that really is something to be guilty of. So are these two more wrong because they had their moment on the Internet?
Finally, if blogging for pennies is the only thing these two were doing to raise funds, I guess I'd question it. But if it's one of the many stones they're turning over to meet their goals for their wedding, it's awfully hard to say (in this day and age) that they're not simply being resourceful and exploring every avenue to raise these funds.
I doubt there's any cents (or sense) to be found in my comments since it's 5 a.m., but if I accidentally landed on some I'm all for it.


On Friday 16th January, we were visited by Sir Alan Haselhurst, the MP for Saffron Walden. After guided tours of the schools, Sir Alan spent time with year 5 and 6 answering questions.
The quality of the questions was good. Children asked a wide variety of questions from his experiences of meeting the Queen to MPs' pay; his experiences of World War 2 to his opinion on the proposed expansion of housing in Saffron Walden.
Afterwards, Sir Alan stayed to watch our weekly Celebration Assembly.


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Never the less, the Times also reports that the Apple relationship is so important to Twitter, they've appointed a vice-president, Kevin Thau, to work with Apple full time. Twitter integration was brought to the iPhone and iPad with iOS 5 and increased with iOS 6, which also added Twitter to Notification, and added Facebook integration into the mix. Just this week Twitter also debuted on the Mac with OS X Mountain Lion update's deeper social media integration.
Given that level of integration, it only makes sense for Apple to explore a stake in Twitter. Apple traditionally doesn't like being dependent on technology it doesn't control. It only makes sense Apple would want influence over Twitter's direction -- especially if any competitor ever looked like they might be making a move towards a similar investment, or a buyout.
Likewise, Apple has proven less than adept at trying to spawn their own social media network, namely Ping and integrated a successful network like Ping could be a better strategy, just as Apple CEO, Tim Cook suggested during Apple's Q2 2012 earning call.
Apple doesn't have to own a social network, but does Apple need to be social? Yes.
Apple's relationship with Facebook has been up and down over the years, though Facebook integration is coming to both OS X and iOS this fall. Google has been making a huge push into social with Google+, yet they also compete with Apple in smartphone and tablets, namely, Android.
Would a more intertwined Apple and Twitter be a good thing? It probably wouldn't prevent Twitter working with rival platforms any more than Microsoft's investment in Facebook prevents Facebook from working with Apple. With $117 billion in the bank, Apple wouldn't miss a few hundred million for Twitter. Would it make you feel more secure about Twitter features not going anywhere? Or should Apple keep trying to do their own social thing?
What do you guys think of Apple investing in Twitter? Are there certain social media features you'd like built deep into iOS that just aren't there yet?
UPDATE: Apple's talks with Twitter apparently occurred over a year ago, no talks are currently underway. That, according to Shira Ovide and Jessica E. Vascellaro at The Wall Street Journal and their "little birdies".
People close to Twitter have said the San Francisco company is ahead of 2012 revenue projections laid out last year. Twitter has largely ruled out acquisitions as it builds its business for a potential initial public offering in a year or so.


A shift dress is always on trend! A true classic, our girl's shift is so charming and versatile. Made from the highest quality fabric, this must-have dress fits perfectly on different body types. Every girl will look adorable and feel so comfortable in this beautiful dress. It is perfect for everyday, school, special occasion and vacation wear.
Her favorite dress from now on!
Nice-looking, comfortable and great material!
My daughter picked this dress herself! She loves it. And the material is super sleek and nice.
The material is fantastic and it fits like a dream.


text:
Q: Combine two geom_bars in one ggplot with DIFFERENT colors I have a stacked & grouped plot. I have numbers of tomatoes and apples (two groups) for 3 different years (stacked). I want that the years of the tomotoes have a different color than the years of the apples, so that is it clear which stack is about which fruit. So, for example, first year of tomatoes is dark-blue and for apples is light-blue, second year of tomatoes is dark-green and for apples light-green.
My currunt code is this:
 ggplot() +
      geom_bar(data = dataset,
               mapping = aes(x = var_2, y = number , fill = as.factor(year)),
               stat="identity",
               position='stack',
               width = 35)  +
      geom_bar(data = dataset,
               mapping = aes(x = as.numeric(var_1) + 35 + 0.05 , y = number, fill = as.factor(year)),
               stat="identity",
               position='stack',
               width = barwidth)+
      scale_x_discrete(labels = function(x) str_wrap(x, width = 40)) +
      #scale_fill_manual(values = #current colors but that doesnt work +
      coord_flip()

Some ideas here maybe?
Edit: also fine to add a pattern to one of the two types of fruit.


Since 2012, Arthur has also been an adjunct member of the Boston University School of Law faculty, teaching alternative dispute resolution, negotiation, representation of clients in civil litigation and professional responsibility. Previously, Arthur taught franchising in the Babson College MBA program (2006–2008).
I focus on solving problems efficiently. My goal is to help clients succeed in their core businesses without unnecessary distraction from disputes with business partners. As a proponent of cost-effective methods of identifying interests that can facilitate resolution in ways that courts cannot, I serve as a mediator of franchise and business disputes. That said, I often appear in court or in arbitration on behalf of franchisors and sometimes on behalf of franchisees or distributors with legitimate business complaints that are not easily resolved.
I've tried many cases before juries, judges and arbitration panels and am also listed on the American Arbitration Association neutral panels for franchise and commercial disputes.
I am also consulted by other lawyers to serve as an expert consulting or testifying witness on franchise-related issues including joint-employment, legal malpractice, adequacy of disclosure, vicarious liability and application of franchise regulations to business arrangements.
Significant growth in the global marketplace. As franchise systems expand, it will become increasingly important to efficiently and cost-effectively resolve disputes in a way that minimizes interruptions and maintains good business relationships among all business partners.
Truglio et al. v. Planet Fitness, Inc. et al.
Defense of putative class action over adequacy of fitness club franchisor's membership agreement under state law. Motion to dismiss all counts, except one, granted; case otherwise pending, USDC(NJ).
Cormier v. Pla-Fit Franchise, LLC et al.
Defense of fitness club franchisor's policy of permitting transgender members to use locker rooms with which they self-identify. Complaint by complaining member dismissed. Case currently on appeal to Michigan Court of Appeals.
ABP Corporation v. Statewide Management Inc.
Representation of franchisor in enforcement of arbitration clause against multi-unit franchisee in federal courts in California and Massachusetts. Case settled 2016.
RE/MAX New England, LLC et al. v. Prestige Realty Inc. et al.
Representation of franchisor in action against multi-unit breakaway franchisee. 2014–2016. Case resolved 2016, USDC (MA).
KFC Corporation v. Iowa Department of Revenue, No. 10-1340, United States Supreme Court.
Representation of International Franchise Association in amicus brief filing in connection with KFC Corporation's petition for Supreme Court review of Iowa's taxation of its in-state royalty revenue.
Andersen et al. v. Griswold International LLC.
Defense of franchisor against fraud and unfair trade practices claims by multiple franchisees, USDC (NDCA). Companion cases in Colorado, Minnesota, New Jersey and Pennsylvania. All settled 2016.
FSRO Association Ltd v. Fantastic Sams Franchise Corporation, American Arbitration Association Claim No. 11 114 01221, and Fantastic Sams Franchise Corporation v. FSRO Association Ltd., USDC (MA).
Representation of franchisor in court action to limit franchise association's ability to bring consolidated arbitration proceeding on behalf of multiple association members. Trial court orders 2/3 of association members to bring individual arbitrations and refers issue as to remaining 1/3 of members to arbitrators.
Pinnacle Pizza Co. v. Little Caesar Enters., No. 08-3999, 2010 U.S. App. LEXIS 5801 (8th Cir. Mar. 22, 2010).
Barkan v. Dunkin' Brands, Inc, USDC (RI).
Representation of franchisor in defense of $13 M fraud and breach of contract claims by former franchisee. Jury trial in December 2009 ended in mistrial for juror misconduct, and retrial in January 2010 ended in directed verdict for franchisor after the court barred franchisee's expert witness from testifying. Judgment for franchisor affirmed per curiam at 637 F.3d 634 (1st Cir. 2010).
	G.L.M. Security & Sound, Inc. v. LoJack Corporation, USDC (E.D.N.Y.).
Representation of former distributor of after-market, auto security systems in various contract and tort claims.
Williams et al. v. Kahala Corp., Case No. 10-L-166, Circuit Court, Madison County, IL.
Defense of Blimpie® franchisor in putative class action based on alleged false advertising of amount of meat in "double portion" Blimpie sandwich. No class certified. Settled for de minimis food pantry donation.
Pohlmann et al v. Fiducial Franchises, Inc. et al., 21st Judicial Circuit, St. Louis County. MO (2010).
Defense of financial services franchisor in class action alleging agency and direct liability for franchisee's sale of fraudulent tax credits. Motion for class certification denied by trial court in July 2010. MO Court of Appeals affirmed denial of class certification in July 2011.
Planetarium Travels, Inc. v. American Express Travel Related Services Company, Inc., Index No. 600794/10, Supreme Court, New York County, NY (2010).
Defense of franchisor in action for injunction to compel renewal of franchise agreement and damages. Preliminary injunction denied after hearing; affirmed on appeal. Case pending.
Kiddie Academy Domestic Franchising LLC v. Faith Enterprises DC, LLC, 2009 U.S. Dist. LEXIS 61989 (D. Md. 2009).
Representation of franchisor in defense of multimillion-dollar fraud and breach of contract claims by franchisee. Summary judgment in favor of franchisor on all claims, including award of attorneys' fees.
DeGiovanni v. Jani-King of Boston, Inc. et al., Civil Action No. 07-10066 (D. Mass. 2007); Myers v. Jani-King of Philadelphia, Inc. et al., Civil Action No. 09-1738 (E.D. Pa. 2009).
Defense of putative class actions alleging violation of state wage payment laws, misclassification of franchisees as employees, and unfair and deceptive trade practices. Additional issues include enforcement of forum selection clause, choice of law clause, and inherent "fairness" of royalty and other fees disclosed in FDD and contained in franchise agreement.
Hamilton-Dutt et al. v. Pla-Fit LLC, No. 1:09- cv-10560 (D. Mass. 2009); HD Fit, Inc. v. Pla-Fit, LLC, No. 13-C-09-076764 (Maryland Cir. Ct. 2009); HD Fit, Inc. et al. v. Pla-Fit, LLC et al., American Arbitration Association (Boston 2009).
Defended franchisor against franchisee claims in multiple proceedings for $10 million in antitrust, civil conspiracy and fraud damages based on franchisor's sale of development rights to third party. Litigated in multiple proceedings, including successful action to compel arbitration; settled on extremely favorable and confidential terms.
In Re Fein, Debtor, Bankr. Case No. 08-30185, U.S. Bankruptcy Court for the District of Massachusetts (Western Division), CCH Business Franchise Guide 2008-2009, ¶13,951.
Monster Cable Products, Inc. v. Monster Mini Golf, LLC, No. 2:08-cv-01037-LKK-EFB (E.D. Cal. 2008).
Hotel Associates v. Howard Johnson Franchise Systems (D.P.R. 2003), affirmed per curiam, 198 Fed. Appx. 13 (1st Cir. 2006).
Summary judgment in favor of franchisor on all claims in $22M suit for encroachment and breach of contract.
McDonald's Corp. v. Benito, No. 1:04-cv-01575 (S.D.N.Y. 2004).
Representation of franchisor in contested termination of multiple-unit restaurant franchisee in New York City. After the court denied franchisee's motion for a temporary restraining order, franchisee settled by leaving the franchise system and reimbursing franchisor for all legal fees and expenses.
Carta v. McDonald's Corp., No. 1:03-cv-12237 (D. Mass. 2003).
Defense of self-insured restaurant franchisor in action for bad faith failure to settle insurance claim under state insurance statutes. Court granted franchisor's motion to dismiss, holding that franchisor could not be liable under a statute that applied only to insurance companies.
Superior Walls of America, Inc., v. Weaver Precast, Inc. (E.D. Pa. 2003).
Prosecution of patent infringement action by franchisor alleging franchisee infringed upon franchisor's patent by offering proprietary business process in unauthorized channels of distribution. Case settled on terms favorable to franchisor.
Huntington Learning Centers, Inc., and The Association of Remedial Educators (American Arbitration Association 2003); Huntington Learning Centers, Inc. v. The Association of Remedial Educators (New York County Supreme Court 2003).
Defense of franchisor against claims by 80 franchisees for $20M in alleged lost profits arising from ad fund shortfall, including striking of consolidated damage claims in separate state court litigation; case favorably settled.
Andrews v. Avis Rent a Car and Cendant Car Rental, (Florida Superior Court 2003).
Defense of franchisor against vicarious liability claims by quadriplegic plaintiff injured in one-car motor vehicle accident in Mexico. Case settled.
Bradley et al. v. The Arrow Corporation, Superior Court, Connecticut, 2002.
Hunter v. Superior Walls of America, Inc., No. 0:00-cv-02519 (D. Minn. 2001).
Defense of franchisor against claims by former franchisee for fraud and violation of state franchise registration law. Case included motion to dismiss and motion to disqualify plaintiff's counsel for unauthorized communications with one of franchisor's managerial employees, who was also a named defendant. Case favorably settled.
McDonald's Corp. v. Dat Do, No. 00-1592-A, 2001 U.S. Dist. LEXIS 10457 (E.D. Va. 2001).
Representation of franchisor in termination of multiple-unit franchisee in "rocket docket" jurisdiction. Affirmed by 4th Circuit.
McDonald's Corp. v. Robertson, 147 F.3d 1301 (11th Cir. 1998).
Representation of franchisor in action to enforce termination of long-time franchisee for failure to comply with franchisor's quality, service, and cleanliness standards. Preliminary injunction granted and affirmed on appeal.
McDonald's Corp. v. Michael, No. 0:97-cv-02252 (D. Minn. 1998).
Representation of franchisor in action to enforce termination of franchisee for violation of quality, service and cleanliness standards. Temporary and preliminary injunctions granted.
Dunkin' Donuts, Inc., v. Mandorico, Inc., 181 FRD 208 (D. Puerto Rico 1998).
Representation of franchisor in termination of development rights and defense of Law 75 counterclaim. Case settled on favorable terms.
Specialty Bakeries, Inc. v. HalRob, Inc., 129 F.3d 726 (3d Cir. 1997).
Representation of franchisor in enforcement of arbitration provisions against franchisee of competing franchise system acquired by franchisor for resolution of franchisee claims, including vacating state court injunction against arbitration proceedings.
Cione v. Carvel, Inc., (D. NJ 1995).
Representation of franchisor in defense of civil RICO and fraud claims; two-month jury trial followed by twenty-day jury deliberation; hung jury, case favorably concluded.
Thank you for your request to e-mail Arthur Pressman.
Continue with e-mail to Arthur Pressman.
Regularly featured as one of the top lawyers worldwide in International Who's Who of Business Lawyers, Arthur has also been named as one of the top 100 franchise lawyers in the country by Franchise Times every year since its inception. He has been selected by his peers as a Massachusetts Super Lawyer every year since 2005.
Arthur was selected, through a peer-review survey, for inclusion in The Best Lawyers in America© 2019 in the field of Franchise Law. Arthur has been listed in Best Lawyers since 2007.
Arthur has been recognized for the past eleven years as a "Legal Eagle" by Franchise Times and he was inducted into the Legal Eagles Hall of Fame in 2013.
Arthur is a member of the American Bar Association Forum on Franchising, the International Franchise Association, and the International Bar Association Committee X on International Franchising. As a member of the Forum on Franchising, Arthur has spoken at annual forum meetings on a variety of franchise litigation and dispute resolution topics on multiple occasions from 1990 through 2010. Arthur has also spoken at the Annual IFA Legal Symposium on multiple occasions from 1988 through 2010. Arthur is also a member of the Boston Bar Association and the Barnstable County, MA Bar Association.
For the 2012-2013 academic year, Arthur serves as Lecturer in Law at Boston University School of Law, teaching "Representing Clients in Civil Litigation." Previously, Arthur has been Adjunct Professor at Babson College, Wellesley, MA in the Entrepreneurship Division of its MBA Program, co-teaching "Franchising: Pathway to Wealth Creation," and has taught franchising at Temple University School of Law.
Since 2009, Arthur has served as chairman of South Coastal Counties Legal Services, Inc., a provider of civil legal services to the elderly, disabled and working poor which serves southeastern Massachusetts, Cape Cod and the Islands.


text:
Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α-DNA interactions
Brian J. Deegan, Anna M. Bona, Vikas Bhat, David C. Mikles, Caleb B. McDonald, Kenneth L. Seldeen, Amjad Farooq
Estrogen receptor α (ERα) acts as a transcription factor by virtue of the ability of its DNA-binding (DB) domain, comprised of a tandem pair of zinc fingers, to recognize the estrogen response element within the promoters of target genes. Herein, using an array of biophysical methods, we probe the structural consequences of the replacement of zinc within the DB domain of ERα with various environmental metals and their effects on the thermodynamics of binding to DNA. Our data reveal that whereas the DB domain reconstituted with divalent ions of zinc, cadmium, mercury, and cobalt binds to DNA with affinities in the nanomolar range, divalent ions of barium, copper, iron, lead, manganese, nickel, and tin are unable to regenerate DB domain with DNA-binding potential, although they can compete with zinc for coordinating the cysteine ligands within the zinc fingers. We also show that the metal-free DB domain is a homodimer in solution and that the binding of various metals only results in subtle secondary and tertiary structural changes, implying that metal coordination may only be essential for binding to DNA. Collectively, our findings provide mechanistic insights into how environmental metals may modulate the physiological function of a key nuclear receptor involved in mediating a plethora of cellular functions central to human health and disease.
Journal of Molecular Recognition
https://doi.org/10.1002/jmr.1148
Response Elements
analytical light scattering
circular dichroism
environmental metals
estrogen receptor α
steady-state absorbance
steady-state fluorescence
Deegan, B. J., Bona, A. M., Bhat, V., Mikles, D. C., McDonald, C. B., Seldeen, K. L., & Farooq, A. (2011). Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α-DNA interactions. Journal of Molecular Recognition, 24(6), 1007-1017. https://doi.org/10.1002/jmr.1148
Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α-DNA interactions. / Deegan, Brian J.; Bona, Anna M.; Bhat, Vikas; Mikles, David C.; McDonald, Caleb B.; Seldeen, Kenneth L.; Farooq, Amjad.
In: Journal of Molecular Recognition, Vol. 24, No. 6, 01.11.2011, p. 1007-1017.
Deegan, BJ, Bona, AM, Bhat, V, Mikles, DC, McDonald, CB, Seldeen, KL & Farooq, A 2011, 'Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α-DNA interactions', Journal of Molecular Recognition, vol. 24, no. 6, pp. 1007-1017. https://doi.org/10.1002/jmr.1148
Deegan BJ, Bona AM, Bhat V, Mikles DC, McDonald CB, Seldeen KL et al. Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α-DNA interactions. Journal of Molecular Recognition. 2011 Nov 1;24(6):1007-1017. https://doi.org/10.1002/jmr.1148
Deegan, Brian J. ; Bona, Anna M. ; Bhat, Vikas ; Mikles, David C. ; McDonald, Caleb B. ; Seldeen, Kenneth L. ; Farooq, Amjad. / Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α-DNA interactions. In: Journal of Molecular Recognition. 2011 ; Vol. 24, No. 6. pp. 1007-1017.
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title = "Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α-DNA interactions",
abstract = "Estrogen receptor α (ERα) acts as a transcription factor by virtue of the ability of its DNA-binding (DB) domain, comprised of a tandem pair of zinc fingers, to recognize the estrogen response element within the promoters of target genes. Herein, using an array of biophysical methods, we probe the structural consequences of the replacement of zinc within the DB domain of ERα with various environmental metals and their effects on the thermodynamics of binding to DNA. Our data reveal that whereas the DB domain reconstituted with divalent ions of zinc, cadmium, mercury, and cobalt binds to DNA with affinities in the nanomolar range, divalent ions of barium, copper, iron, lead, manganese, nickel, and tin are unable to regenerate DB domain with DNA-binding potential, although they can compete with zinc for coordinating the cysteine ligands within the zinc fingers. We also show that the metal-free DB domain is a homodimer in solution and that the binding of various metals only results in subtle secondary and tertiary structural changes, implying that metal coordination may only be essential for binding to DNA. Collectively, our findings provide mechanistic insights into how environmental metals may modulate the physiological function of a key nuclear receptor involved in mediating a plethora of cellular functions central to human health and disease.",
keywords = "analytical light scattering, circular dichroism, environmental metals, estrogen receptor α, isothermal titration calorimetry, steady-state absorbance, steady-state fluorescence, zinc fingers",
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doi = "10.1002/jmr.1148",
journal = "Journal of Molecular Recognition",
T1 - Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α-DNA interactions
AU - Deegan, Brian J.
AU - Bona, Anna M.
AU - Bhat, Vikas
AU - Mikles, David C.
AU - McDonald, Caleb B.
AU - Seldeen, Kenneth L.
AU - Farooq, Amjad
N2 - Estrogen receptor α (ERα) acts as a transcription factor by virtue of the ability of its DNA-binding (DB) domain, comprised of a tandem pair of zinc fingers, to recognize the estrogen response element within the promoters of target genes. Herein, using an array of biophysical methods, we probe the structural consequences of the replacement of zinc within the DB domain of ERα with various environmental metals and their effects on the thermodynamics of binding to DNA. Our data reveal that whereas the DB domain reconstituted with divalent ions of zinc, cadmium, mercury, and cobalt binds to DNA with affinities in the nanomolar range, divalent ions of barium, copper, iron, lead, manganese, nickel, and tin are unable to regenerate DB domain with DNA-binding potential, although they can compete with zinc for coordinating the cysteine ligands within the zinc fingers. We also show that the metal-free DB domain is a homodimer in solution and that the binding of various metals only results in subtle secondary and tertiary structural changes, implying that metal coordination may only be essential for binding to DNA. Collectively, our findings provide mechanistic insights into how environmental metals may modulate the physiological function of a key nuclear receptor involved in mediating a plethora of cellular functions central to human health and disease.
AB - Estrogen receptor α (ERα) acts as a transcription factor by virtue of the ability of its DNA-binding (DB) domain, comprised of a tandem pair of zinc fingers, to recognize the estrogen response element within the promoters of target genes. Herein, using an array of biophysical methods, we probe the structural consequences of the replacement of zinc within the DB domain of ERα with various environmental metals and their effects on the thermodynamics of binding to DNA. Our data reveal that whereas the DB domain reconstituted with divalent ions of zinc, cadmium, mercury, and cobalt binds to DNA with affinities in the nanomolar range, divalent ions of barium, copper, iron, lead, manganese, nickel, and tin are unable to regenerate DB domain with DNA-binding potential, although they can compete with zinc for coordinating the cysteine ligands within the zinc fingers. We also show that the metal-free DB domain is a homodimer in solution and that the binding of various metals only results in subtle secondary and tertiary structural changes, implying that metal coordination may only be essential for binding to DNA. Collectively, our findings provide mechanistic insights into how environmental metals may modulate the physiological function of a key nuclear receptor involved in mediating a plethora of cellular functions central to human health and disease.
KW - analytical light scattering
KW - circular dichroism
KW - environmental metals
KW - estrogen receptor α
KW - isothermal titration calorimetry
KW - steady-state absorbance
KW - steady-state fluorescence
KW - zinc fingers
U2 - 10.1002/jmr.1148
DO - 10.1002/jmr.1148
JO - Journal of Molecular Recognition
JF - Journal of Molecular Recognition
10.1002/jmr.1148

redpajama_set_name: RedPajamaCommonCrawl


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In a blow-out the 4th quarter is usually much lower scoring than the rest cuz subs are playing, bad luck but I've been on the same side of this sort of thing.
The bucks are just terrible. I can't believe I took them +10. Shame on me!
[Quote: Originally Posted by theKINGdanny] In a blow-out the 4th quarter is usually much lower scoring than the rest cuz subs are playing, bad luck but I've been on the same side of this sort of thing.
Did you really expect it to go over?


Sixty years ago, in October 1956, Grant Avenue Baptist Church was established because a handful of people were committed to sharing Christ with Corvallis and the campus of Oregon State University. That is still the desire of our congregation.
Our primary goal is to love God and to love others. We are a family and we welcome anyone seeking to learn more about God and the scriptures.


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Medioxyoppia nagoyae är en kvalsterart som beskrevs av Ohkubo 1991. Medioxyoppia nagoyae ingår i släktet Medioxyoppia och familjen Oppiidae. Inga underarter finns listade i Catalogue of Life.

Källor

Spindeldjur
nagoyae

redpajama_set_name: RedPajamaWikipedia


Sharing home brew information and resources.
Our club bought a bunch of bourbon barrels so I brewed a big stout to put in my barrel. To keep the barrel wet until the beer was ready, I put a fifth of Glenlivet Scotch in the barrel. I kept it in barrell only ten days since other brewers said the wood was strong after just two weeks. The bourbon dominated the wood so I'm letting it age in the keg to mellow out.


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What's Happening with the Health Care Bill
Differences from the ACA, AHCA, BCRA and What's Next
On July 13, 2017, the Senate revealed their version of the already House-passed American Health Care Act (AHCA). The Better Care Reconciliation Act (BCRA) made some significant updates, but on July 18 the legislation was determined to not have the support it needed to pass the Senate.
This latest hurdle in the GOP's promise to repeal and replace Obamacare sparked discussion about passing a "repeal now, replace later" legislation. However, after a late night meeting on July 20, the Republican Party is more optimistic that a version of the BCRA will come to pass.
Senate Majority Whip John Cornyn said "I'm more optimistic that that [some version of the Better Care Reconciliation Act coming back] would be the case. But if there's no agreement, then we'll still vote on the motion to proceed, but it'll be to the 2015 just-repeal bill."
With the uncertainty and changes within in the current political landscape, it is easy to lose track of policies that are being debated. Outlined below are some of the key points of disagreement, and how each bill addressed those challenges.
Tax credits under the ACA are based on income, age and geography.
The AHCA includes an advanceable tax credit based on age and family size.
The BCRA takes into account income level, and geography as well as age. However, the plan is more selective than the ACA, so people need to make less money than before to receive them.
Coverage and cost cannot be dependent on pre-existing conditions according to the ACA.
Under the AHCA, $8 billion is allocated to fund high-risk pools. Pools provide coverage if you have been locked out of the individual insurance market because of a pre-existing condition, and are subsidized by a state government. The premium is up to twice as much as individual coverage.
Coverage and cost cannot be dependent on pre-existing conditions according to the BCRA.
INDIVIDUAL MANDATE
The ACA requires Americans to have health coverage, if they don't they must pay a fine. There is also an employer mandate requiring large companies to provide health insurance for their employees.
Under the AHCA, the mandate is eliminated, but insurers are allowed to inflict a surcharge on consumers who purchase a new plan after letting their previous coverage lapse. The employer mandate is completely eliminated.
Instead the premium surcharge outlined in the AHCA, the penalty for people who had a break in coverage is having to wait six months before getting new coverage. The employer mandate is also still eliminated.
The ACA expanded Medicaid with enhanced federal match for expansion population.
The ACA's plan to grow Medicaid is halted. Along with other limitations, new enrollment freezes in 2020 under the AHCA.
Under the BCRA, federal contribution is based on general state match percentage starting in 2023.
The ACA requires insurance to offer 10 essential health benefits. Essential health benefits include prescription drugs, maternity care, emergency services, and mental health care.
Under the AHCA, if a person did not maintain continuous coverage, states may apply charge sick people more or drop essential benefits.
According to the BCRA, states may apply for waivers to drop essential benefits, but coverage cannot be sold for more or denied to people who are sick.
There are a lot of questions up in the air about the future of health care under the Trump Administration. All that can be concluded for sure is that change is coming. To stay up to date on new rules, regulations and policies under the new administration, medical industry leaders can gather at conferences or join our mailing list for regular updates.


Amazon Price: $4.83 $4.83 (as of March 1, 2019 10:05 am – Details). Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on the Amazon site at the time of purchase will apply to the purchase of this product.
Use Merthiolate as a first aid aintiseptic.
Online Course: Natural Solutions To Getting Trim Will You Finally Make Good On Your Promise And Set Your Goals To Improve Your Fitness And Live The Healthy Lifestyle You Want?
Online course: The Easiest and Quickest Ways To Lose 10 Pounds Studies show obesity may soon overtake tobacco as the leading cause of death in America. Who Else Wants To Quickly Lose 10 Pounds Over And Over Again?
"Character is what you are in the dark."


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It's amazing how few people Harvey has killed
Perhaps a slightly ghoulish way to think of it but the death toll appears to be 10 people at present. 10 too many of course, a tragedy each and every one.
And yet, and yet. Firstly, imagine a storm this bad in an economically undeveloped country. We wouldn't be just creeping up into double digits.
But also, US death rate is some 800 per 100,000 people each year. There're 2 million in Houston (the city, not the surrounding area). We therefore expect some 45 deaths a day in normal times. That toll of 10 is over several days. We're in fact seeing a 10% rise in the death rate as a result of a vast and huge storm.
Yes, 10 deaths too many. And yet it's an amazingly small, tiny, number. It being economic development that makes it such.
previousSome people, eh?
nextSabbatical
21 thoughts on "It's amazing how few people Harvey has killed"
JuliaM August 29, 2017 at 8:13 am
Spot on. And no scenes like those during Katrina. Just people mucking in and helping.
Kevin Lohse August 29, 2017 at 8:30 am
To continue on the ghoulish line. How many of those 45 deaths a day would be down to other than natural causes, e.g. road traffic accidents, work-related accidental deaths or deaths from criminal activity? It might be possible to ague that Tropical Storm Harvey (NOAA designation) has actually saved lives overall! (I have fb friends in the middle of this who are sitting on an island in the deluge.)
argue, dammit
Bloke in Swindon August 29, 2017 at 8:49 am
JuliaM,
Plenty of areas did the same thing around Katrina, like Florida and Mississippi. The MSM just chose to ignore them in favour of covering the combined natural/man-made disaster of New Orleans and labelling George W Bush a racist.
NDReader August 29, 2017 at 9:20 am
"But also, US death rate is some 800 per 100,000 people each year."
Either the average life expectancy is 125 years, or there are an awful lot of young folk immigrating or old folk emigrating.
Tim Newman August 29, 2017 at 9:48 am
Plenty of areas did the same thing around Katrina, like Florida and Mississippi.
Yup. Friend of mine lives in Pensacola, he gets battered by hurricanes but everyone mucks in. I believe his job is to stand at one end of the neighbourhood with a large firearm deterring looters.
David Moore August 29, 2017 at 10:01 am
Am I the only one who perceives the Guardian as positively salivating at the prospect of Harvey killing thousands?
It's using words like 'catastrophe', and all I can see is a very reasonable response to a very bad storm. Hell, there even seems to be very good corporation between people and local/fed agencies, who are not being as heavy handed as I've heard about in past US disasters.
bloke in spain August 29, 2017 at 10:01 am
@NDReader
"Either the average life expectancy is 125 years, or there are an awful lot of young folk immigrating…."
UK's is 940/100,000.(Ever helpful CIA World Factbook) So headed in the same direction. And likely, even further along. What with illegals in lower age groups & other immigrants missing from the figures.
"…or old folk emigrating"
That's something you see in London's Cypriot community. Even Cyps born there like to make their pile in the UK, then live out their final years in Cyprus. And there's people like me. Any dying I intend doing won't be done in the rain & cold at the slender mercy of the NHS..And anyway. It's always been my ambition to die of gunshot wounds in the bed of some other bloke's wife. I need a country with decent firearms laws.
Bloke no Longer in Austria August 29, 2017 at 10:46 am
"Firstly, imagine a storm this bad in an economically undeveloped country. We wouldn't be just creeping up into double digits."
You mean a 3rd World corrupt, hell-hole like…err.. New Orleans ?
Idiots on Today this morning citing Harvey as proof of global warming and what a fool Trump is for pulling out of Paris Accord. Would be funny if it weren't so depressing.
DP August 29, 2017 at 10:56 am
Dear Mr Worstall
Compare and contrast:
https://en.wikipedia.org/wiki/1900_Galveston_hurricane
DocBud August 29, 2017 at 11:44 am
This had the same Saffir-Simpson category (4) as Harvey:
https://en.m.wikipedia.org/wiki/Cyclone_Nargis
dearieme August 29, 2017 at 12:21 pm
But Harvey may be a Fake news category 4.
"As reported by satellites, Harvey peaked at a sustained speed of 115kt, or 132mph, just before landfall.
However, this appears to be at odds with the land based data, where the highest PEAK GUST was 132 mph. Wind gusts are typically about 1.3 times as high as 1-minute sustained speeds, according to NOAA, which suggests that Harvey's sustained speeds at landfall were about 100 mph, making it a Cat-2 hurricane.
Note that hurricanes like Carla and Celia were much more powerful at landfall. Once more, this raises questions about the current practice of comparing satellite data with historical land data. This often results in claims that storms these days are more powerful than in the past"
https://notalotofpeopleknowthat.wordpress.com/2017/08/28/storm-harvey-update/
Carl Edman August 29, 2017 at 4:30 pm
Quite so.
My favorite example of this are the '88 Armenian quake and the '94 Northridge quake. They are quite similar: they occurred within a few years of each other; they both hit densly populated areas; their strength was almost the same (6.7 vs. 6.8 on the Richter scale).
One difference: the Northridge quake killed 57; the Armenian quake 25,000 to 50,000.
Never, ever forget: It's good for a society to be rich.
Bloke in Costa Rica August 29, 2017 at 5:46 pm
Even if you're slightly rich the difference is amazing. We had a 7.6 here five years ago: 2 killed (one from a heart attack). Bam had a 6.6 in 2003 and 30,000 died. Moral of the story: building houses out of reinforced concrete rather than cowshit is a smart move if you live in an earthquake zone.
synp August 29, 2017 at 6:32 pm
"Moral of the story: building houses out of reinforced concrete rather than cowshit is a smart move if you live in an earthquake zone."
I'd rather have cowshit fall on my head than reinforced concrete.
Jokes aside, most American houses are built of what feels like plywood specifically to meet earthquake resistance standards.
ZT August 29, 2017 at 8:15 pm
Civil Engineering Professor: "It's better to be in a wood-framed house than a masonry house if there's an earthquake."
Student: "Because the wood house is stronger?"
Prof:"No, it's easier to dig you out of the rubble."
Chris Miller August 29, 2017 at 8:52 pm
most American houses are built of what feels like plywood specifically to meet earthquake resistance standards
When the Mythbusters crew accidentally shot a cannonball through a Californian dwelling, they demonstrated it was constructed from chicken wire and papier mâché.
Bloke in North Dorset August 29, 2017 at 10:16 pm
Coyote was recently complaining that his house was effectively a Farrady cage because of the same design: http://www.coyoteblog.com/coyote_blog/2017/08/i-think-i-figured-out-my-wireless-issues-i-am-living-in-a-damn-faraday-cage.html
Ed Snack August 30, 2017 at 3:41 am
Several issues, one the time of day of a quake makes a lot of difference to death tolls in many (but not all) quakes; and even more so in places where the houses are prone to collapsing.
Wooden houses don't just make it easier to dig one out so to speak, they flex and very rarely collapse catastrophically though they can certainly be heavily damaged. A major cause of fatalities in such houses is the collapse of unsecured masonry chimneys.
In NZ's recent earthquakes, virtually all fatalities occurred in modern multi-storey ill-specified (or not built to spec) buildings that did collapse and from old (1900-1930's say) commercial building facades with elaborate copings that were not earthquake strengthened and not required to be so because of age (and historical preservation rules). Others were from chimney collapses, very, very, few (if any) from collapsed wooden houses. In the latest one, there were two fatalities, one I think medically related and the other from the collapse of a chimney and related parts of a historic rammed earth two storey homestead.
Bottom line, modern (though maybe not too "modern") wooden framed houses without free standing masonry chimneys are remarkably safe in even major damaging earthquakes.
Bloke in Costa Rica August 30, 2017 at 5:36 am
Perhaps, but mud bricks are absolutely fucking terrible.
Pingback: Harvey – wmconnolley: scienceblogs.com/stoat archive
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InterviewPayton Turner November 29, 2016 new york, brooklyn, kia warren, revel in dimes, musician, girls at library, gal
A brief note from GAL:
GAL was supposed to meet for Kia's interview and photoshoot on the day after the election: a day that was going to be covered in shattered glass. We'd be celebrating while working together on a project that cares deeply about what women have to say about themselves in connection to literature and the act of reading. Not what they say about their bodies, the contents of their makeup bags, or their clothing choices. GAL is here to help women connect with one another over books and ideas, not brands and looks.
Unfortunately, that day didn't turn out as we had hoped. We had to reschedule Kia's shoot because all three of us felt a form of devastation. GAL is run by two women who believe in the sanctity of first amendment rights, of respecting and appreciating diversity, and in equality. We want to be a publication that you turn to for inspiration and solace, that continues to honor and highlight the important role literature plays in women's inner and outer lives, and aid you in connecting to each other via books. GAL hopes you'll stick with us for the next four years. We'll be here.
- Payton Turner & Eliza Wexelman
Kia grew up on Long Island and currently lives in Bedstuy, New York. She is the lead singer of the band Revel in Dimes, a songwriter, and a bartender at East Village Goodnight Sonny. Kia fuels her creative energy by surrounding herself with works by classic American playwrights such as Lorraine Hansberry and August Wilson along with Zadie Smith, Joan Didion, and Jack Kerouac. GAL was curious to know more about how reading and songwriting are linked in her world. Find that, and more, below.
Photography by Lauren Pisano
Girls at Library: How did you become a reader?
Kia Warren: My parents taught me how to read before I even started going to school. My dad was my biggest influence in reading, and also in helping me discover what impacted me or what I liked and why. Even artistically, he has guided me. He really helped me connect the dots through reading.
GAL: Did you and your father read together? Did he read you any specific books when you were growing up?
KW: No, he never read anything in particular to me. I do remember him making a big deal out of getting me a library card though and taking me to the library and saying "Be free!" to me.
I really did feel this sense of freedom at the library, you know what I mean? Being able to choose what I wanted to read and what to expose myself to. I don't remember if it was a neighbor or a kid from camp, but one of the two introduced me to the Ramona books by Beverly Cleary. I was obsessed with that whole series. Ramona is so crazy and funny. I thought I was Ramona!
I love the main female characters in both From The Mixed Up Files of Basil E. Frankweiler and the Ramona series. Two little girls with big senses of freedom and adventure who are kind of like, bossy. I could definitely identify with that! Even if I didn't know it consciously at the time as a child, I did identify with that and it helped shape me.
GAL: What's the connection between being a musician and a reader?
KW: Storytelling and intention. When I sit down to write a song, the most important thing is how I feel while I'm writing. Not necessarily what I want to evoke, but what I really want to say. Part of my training in college was acting, and my teachers would tell us that every single line has to have intention behind it in order to be believable and to resonate, and I think the same is true with any kind of storytelling. Having a strong intention makes both performing and hearing music a more powerful and engaging experience.
When I'm performing something I want to be able to see it and feel it, and I think that comes from reading a lot. Especially from reading plays and my acting experience. I feel like you can tell the difference between someone who is just writing words rather than actually saying something authentic and genuine. I don't think you can get to that point without having read good work.
GAL: Are you a fan of any particular playwrights or plays?
KW: Edward Albee is one. I also love Suzan-Lori Parks and August Wilson. All the classic American playwrights. John Patrick Shanley.
GAL: What was your reaction to the news that Bob Dylan won the Nobel Prize for Literature?
KW: I loved it. I thought it was incredible. Knowing his body of work so well, and knowing how I feel about music being a healing art form, it thrilled me. I was really put off by people booing it, saying that there are so many other important authors out there who deserved to win such a prestigious award. But, you know, why not award it to a musician? It takes just as much, if not more effort, to put yourself out there so entirely the way musicians do. I thought he definitely deserved it. His response to it on the other hand left a little something to be desired. That's pretty classic Dylan though.
GAL: What inspires your songs?
KW: I'm a big dreamer. A lot of inspiration actually come from dreams I've had. When I sleep I have such vivid dreams. Maybe that comes from just putting down a book before bed, I'm not exactly sure. I end up waking up the next day, and after thinking about what I've dreamt, I try to re-create the story and the way it made me feel on pen and paper.
GAL: Do you have any favorite books about music or musicians that you'd recommend to GAL readers?
KW: Patti Smith's Just Kids is one of my favorite books ever. Reading about a musician and their process with the backdrop of the 60's and 70's is incredible. I couldn't put it down.
GAL: What books are you reading right now?
KW: Zadie Smith's NW. I'm also going back to Joan Didion's Slouching Towards Bethlehem. I'm re-visiting Richard Wright's Native Son. Those are the three on my nightstand right now.
GAL: Who are you listening to right now?
KW: I'm listening to a lot of Solange. It's a very difficult thing to express your feelings and have the result be so poignant. The album is right in the pocket from beginning to end. It's not pushy: it doesn't feel like she's pushing an agenda. But it's so necessary right now. She says things that need to be said. I've met her in person several times and I have to say she puts her money where her mouth is. She is who she is in those songs and isn't afraid to say what she's saying. I feel encouraged by her.
Otherwise, I don't know, I must be stuck in a time warp. I mostly listen to a lot of sixties and seventies music. Tried and true stuff. Sade and Caetano Veloso.
GAL: Besides being a musician, you also work in hospitality. That's tough. You have to be a natural storyteller behind the bar and also a protector of your own personal narrative as well as an absorber of other people's narratives. How do you do it?
KW: It's energy exchange. That's all you're really doing. When people get drunk they do tend to tell you personal things. You often see a side of humanity that you don't usually see on the streets. It's intimate, and gets to be so really quickly. My energy is so important to protect. I can't just take on anybody's problems or whatever they need to dump out. So I create boundaries. I have my stock stories and responses, so it's not all of me pouring out all the time when somebody wants to hear my life story and chat about theirs.
GAL: How did you choose the name Revel in Dimes for your band?
KW: It's so funny, I actually met the guys in the band after they had the name. I asked them what it meant, and my guitarist told me that once upon a time he was leaving a loud club and asking his friend if she wanted to share a cab with him. He was rubbing two dimes together and the friend asked him "What? You're reveling in dimes? Well that's good, man." And he was like, I definitely didn't say that but it's funny you said that. I like that you said that. It's a message that says be happy with what you have. That's the feeling behind the band.
GAL: Are you reveling in dimes right now?
KW: Well yeah (laughs) I am! I recently got back from a tour in Europe with the band and am happy with what I did.
GAL: When did you get back to New York from tour?
KW: Election day. I was thinking of extending the trip, but there was no way I was going to miss what we thought would be such a historical moment. My mind was completely…I didn't even fathom that this result was a possibility. So the high of coming off tour, and then the low of the election outcome was horrible. I even went so far as to ask my sister who has kids if that's what postpartum feels like. She said yes, close, but maybe not quite as bad (laughs).
GAL: We're devastated by the election. What should we read or do to feel better?
KW: Whatever anyone can do to educate themselves is key. It is such a comfort to go back to resources like Lorraine Hansberry and to the writing and speeches of civil rights leaders. It has happened before and hopefully one day it will stop happening, but with this election it's sure to happen again. It behooves everyone to get in touch with who they are as people. There are so many people who have gone before us, who represent us, and enriching yourself with their knowledge is helpful. Taking solace in people who have experienced what we're still experiencing makes it feel less desperate and isolating. It's really important to do.
GAL: Please recommend 3 books and the reasons for your choices.
KW: The Creative Habit by Twyla Tharp. Across the board, even if you're not specifically a writer or a painter, we're all creative in some way. It speaks to that part of you. If you want to suss out what's going on in your life and how you want to focus your energy and want to wake up your body – it's is the perfect book for that.
Outliers: The Story of Success by Malcolm Gladwell. There's that saying "overnight success" and that book really debunks the whole myth behind it. It shows the reader what it takes to create a great product or for an artist to create great work and even the historical context behind both. It's a wealth of information.
There's a really beautiful book by Edwidge Danticat called Breath, Eyes, Memory. It's about the connection between a mother and her daughter who moved from Haiti to America. It's emotionally gripping as well as culturally vivid. The intensity of the relationship between the mother and the daughter is what I think a lot of women have experienced with their own mothers. The main character uses her memory to escape the harshness of her reality. It's one of those literary tools that I'm a sucker for. Check it out. The author is also Hatian-American and that's cool too.
Follow Kia on Instagram and see Revel in Dimes live!
All photography is courtesy of Lauren Pisano.
Payton Turner
InterviewPayton Turner December 06, 2016 girls at library, gal, rachael yaeger, human nyc, new york city, new york, manhattan, reading
InterviewPayton Turner November 08, 2016 leigh plessner, new york, brooklyn, catbird, charlotte's web, artist


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Zierikzee, NL
Location: Café De Wildeman, Havenplein (temporarily)
The Dutch artist initiative Wallbreakers/Muurbrekers demonstrates against the ever-new construction of border walls and expresses its hope for a world without walls.
On the 25th anniversary of the fall of the Berlin Wall five segments of the Wall were picked up by cargo sailing ships in Berlin and were shipped to the Netherlands.
One of these segments was on the terrace of the Café De Wildeman in Zierikzee in November 2014. Various events and activities accompanied the temporary installation. A local TV station reported in November 2014. The current whereabouts of this Wall segment is unknown. Additional information can be added directly to this page via a comment.
The other segments that were picked up by ship in Berlin are in Amsterdam (temporarily), Arnheim und Heerlen.
© Still aus TV Clip
Photo above and background:
Still aus TV Clip.
← Arnheim, NL
Heerlen, NL →
The Wall Net > The Berlin Wall in... > Europe > Netherlands > Zierikzee, NL