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Murrey and Blue
murreyandblue
NOT AGAIN! THE LATEST FROM A CAIRO DWELLER …
Richard Duke of Gloucester being offered the crown by the Three Estates at Baynards Castle, June 1483. Painting by Sigismund Goetze at the Royal Exchange…(or according to some.. Richard in the actual act of 'usurping' the throne)…
I came across this article on a forum devoted to late medieval Britain.
Unfortunately I read it..5 minutes from my life I will never get back again… but as I was laid up with a bad head cold I had nothing much better to do. I should have been warned by the photo of a little girl in what looked like an attempt at Tudor costume and the words 'I have no idea who this little girl is but she is adorable. Little kids in this era were adorable and vulnerable too ..just like modern children..lets keep that in mind'. This should have alerted me to the fact the writer was a writer of rubbish. Nevertheless I cracked on. As it transpired the article has more holes in it than a hairnet…and worse was to come.
John Howard, having been cheated out of his inheritance, which 'seems to have stuck in his craw' then went on to become 'one of the first men to help the new king's uncle usurp his throne and become King Richard III'. When I challenged the word 'usurp' I received the reply of a emoji rolling on the floor laughing. It then became clear to me the quality of the author's debating powers were going to be found somewhat lacking. But casting that aside for the moment lets look at the word 'usurp' as used by the author to describe the actions of Richard. The late historian John Ashdown-Hill addressed this point very well. "Definitions of the verb 'usurp' include include terms as to seize power by force and without legal authority…Richard III did not gain the throne by fighting a battle nor did he seize the crown. He was offered the crown by the Three Estates of the Realm. Later the decision of the Three Estates of the Realm was formally enacted by the Parliament of 1484′ (1) . Thus to describe Richard as a usurper is incorrect and a nonsense."
Not content with calling Richard a usurper, John Howard, later Duke of Norfolk is next in line to be maligned by the statement regarding Anne Mowbray, (the 4 year old heiress of John Mowbray who died just before her ninth birthday) 'All that John Howard could do was wait and hope something happened to Anne…'! This is quite an offensive thing to say as well as ludicrous as no source has come down to us informing us of Howard's personal thoughts on this matter and which I very much doubt would have been 'hoping' for the death of a small child. Incidentally, he was raised to the Duchy of Norfolk whilst the "Princes", including the previous in suo jure Duke, were known to be alive – see p.78 and pp.117-124 of The Mythology of the "Princes in the Tower", also by Ashdown-Hill.
Howard later went on to fight and lay down his life for his king aged 60 years old. This colossus of a man could easily have wormed his way out of fighting, as others did, with his age as an excuse. He did no such thing and its a great pity that we have modern day pip-squeaks having the brass neck to disparage such a man. The author needs to hang their head with shame but I doubt if that will happen any time soon.
As we go on we see Lady Eleanor Butler nee Talbot – a lady of the nobility and daughter to the great John Talbot lst Earl of Shrewsbury a, sister to the Duchess of Norfolk and a lady known for her piety – described as one of King Edward's 'side pieces'…(I know, I know..my guess is this is a stab at 'bit on the side' but your guess is as good as mine). She was in actual fact no such thing, being the legal wife of Edward who married her in order to get her into bed. Surely Eleanor deserves more respect than this….as I said pip-squeaks and all.
The writer then follows up with a message touching on the execution of Lord Hastings to prove her point that Richard was a Bad Man. I say 'touching' in a very loose way as she makes no attempt to explore, let alone mention, what reasons were behind the execution only pointing out, unnecessarily, that Hastings was executed 'even though he was one of the most richest and powerful men in the country'..what has this got to do with it? Furthermore…'Richard had him dragged out and beheaded on a log'. Presumably Dickens, who was unborn, or More, aged five at the time, cannot be taken seriously as eye-witnesses? Is it not about time this myth was debunked? Three accounts survive of the dramatic events at the meeting at the Tower that day – those from Historical Notes of a London Citizen 1483/84, Mancini and Croyland (2) – none of which mention the infamous log.
A log, something that Lord Hastings was NOT beheaded on…
Hastings was probably, as Carson points out, executed under the Law of Arms (3), having tried to eliminate the Dukes of Gloucester and Buckingham and been judged by the Constable's Court, Gloucester being Lord High Constable at the time. In much the same way, Rivers, Vaughan and Grey were judged by the Earl of Northumberland, the designated Vice-Constable.
The Mythology of Richard III chapter 6 p74 John Ashdown-Hill.
Historical Notes of a London Citizen 1483/8, English Historical Review, Vol. 96. p588 Richard Firth Green, Mancini p.89, Croyland p.479-80. I am indebted to Peter Hammond and Anne Sutton for their very useful book, Richard III The Road to Bosworth Field, a complete and handy reference to all the primary sources covering Richard's reign.
The Maligned King p.98, but Carson's other book illustrates the powers of the Constable and Protector and the documents assigning the role to Gloucester.
Posted by sparkypus in art, genealogy, law, religion, sources and tagged "Princes", "Tudor" "sources", Anne Mowbray, Annette Carson, Baynard's Castle, bigamy, Charles Dickens, children, denialists, Domenico Mancini, Duchess of Norfolk, Earl of Northumberland, facial reconstruction, Hastings Execution, Henry of Buckingham, Historical Notes of a London Citizen, John Ashdown-Hill, John Earl of Shrewsbury, John Howard Duke of Norfolk, Lady Eleanor Talbot, Lord High Constable, Lord Protector of the Realm, pre-contract, Richard III, The Maligned King, The Mythology of Richard III, The Mythology of the "Princes in the Tower", Thomas More, Three Estates, Titulus Regius, usurpation
6 thoughts on "NOT AGAIN! THE LATEST FROM A CAIRO DWELLER …"
viscountessw on 19/06/2019 at 9:48 am said:
Excellent post, sparkypus. Thank you. You're right, some people do write a load of old rubbish. Cobblers, some might say.
sighthound6 on 19/06/2019 at 9:52 am said:
John Howard was cheated of his rightful inheritance (after Anne Mowbray died) by a shameless piece of legislation which altered the normal rules of inheritance. Richard II gets absolutely crucified by historians for doing *far* less, indeed it is trotted out as one of the chief reasons why he was deposed. But when Edward IV (maybe we should call him the Blessed Edward IV, or St. Edward IV) does something which is far less justified (Howard had not committed treason, nor was he even hostile to Edward, but a very loyal supporter) this is somehow fine and dandy. And note carefully this was not the one and only time Edward interfered with the laws of inheritance. He did the same thing in the case of the Exeter inheritance, and of course, he ripped off the Countess of Warwick for the benefit of his brothers. This last case does attract some criticism – but only because it benefited Richard, who obviously twisted his saintly brother's arm.
hoodedman1 on 19/06/2019 at 8:55 pm said:
Funnily enough, I guessed who the author was before I even clicked on the link. Some other posts by the same person also seem rife with much over-wrought angst and melodrama, to say nothing of making excuses for Henry VIII's tyranny due to (unproven) medical reasons.
Glenis Brindley on 19/06/2019 at 10:44 pm said:
What a load of rubbish! Unfortunately we seem to be seeing more of this sort of thing and it gets more that a little wearing. I sometimes feel I'm running the opposite way to the crowd! Please, let it stop.
suzanne on 20/06/2019 at 9:40 pm said:
I read that article too. The writer of that article seems to have forgotten that john howard was a loyal yorkists, he was loyal to Edward iv. And how did Edward iv repay him by cheating him out of his inheritance. If another king did that e.g Edward ii, Richard ii, Richard iii they would be criticized mercilessly but since this dear st. Edward iv no problem.
The writer of that article is very much pro Tudor and makes medical excuses for Henry viii tyranny.
sparkypus on 20/06/2019 at 10:21 pm said:
Thank you. As I said the writer is a writer of rubbish…
The ghosts of Hellens Manor….
The first "red carpet" in England….?
Doggeing "Tudor" footsteps?
Ten medieval scandals….!
Wenceslaus Hollar, by Gillian Tindall…
URL on Leicestershire's griffin…
The first "red… on Some dilgirunt for His Majesty…
The first "red… on Did Anne of Bohemia die of…
The first "red… on And the king's hair seet…
The first "red… on Hey, Richard II and St Edward…
A Sprig of Broom
Annette Carson
Barbara Gaskell Denvil
Before the second sleep
Bretwalda Books
Brian Wainwright
Dr. John Ashdown-Hill
Giaconda
Helen Rae
Jennifer C. Wilson
Jo's Eclectic Collection
Paul Trevor Bale
Ricardian Loons
Sunnes and Roses
The Dragonhound
The Mortimer History Society
The Yorkist Age
The play's the thing


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Q: Find all the locations of `0000` from string by python I want to find all the locations of 0000 from string.
text = "001111000000010100000"
for m in re.finditer(r"0{4}", text):
    print(m)

This sample code result is below.
<_sre.SRE_Match object; span=(6, 10), match='0000'>
<_sre.SRE_Match object; span=(16, 20), match='0000'>

I can see where finditer found 0000 by span.
But what I was expecting is different.
My expectation is below.
<_sre.SRE_Match object; span=(6, 10), match='0000'>
<_sre.SRE_Match object; span=(7, 11), match='0000'>
<_sre.SRE_Match object; span=(8, 12), match='0000'>
<_sre.SRE_Match object; span=(9, 13), match='0000'>
<_sre.SRE_Match object; span=(16, 20), match='0000'>
<_sre.SRE_Match object; span=(17, 21), match='0000'>

How can I achieve my expectation?
If there is other useful built in method or python package, please advise me.
Thanks!
This question looks like same as mine at a grance.
However my question's point is location, not a string.
Python regex find all overlapping matches?
After reading above question, I got a hint.
Here is my modified code.
text = "001111000000010100000"
for m in re.finditer(r"(?=(0{4}))", text):
    print(m)
    print(f"Indexes: {m.span(1)}")
    print(f"Matched string: {m.group(1)}")

And the result is here.
<_sre.SRE_Match object; span=(6, 6), match=''>
Indexes: (6, 10)
Matched string: 0000
<_sre.SRE_Match object; span=(7, 7), match=''>
Indexes: (7, 11)
Matched string: 0000
<_sre.SRE_Match object; span=(8, 8), match=''>
Indexes: (8, 12)
Matched string: 0000
<_sre.SRE_Match object; span=(9, 9), match=''>
Indexes: (9, 13)
Matched string: 0000
<_sre.SRE_Match object; span=(16, 16), match=''>
Indexes: (16, 20)
Matched string: 0000
<_sre.SRE_Match object; span=(17, 17), match=''>
Indexes: (17, 21)
Matched string: 0000

This is what I was expecting.
Thank you for telling me good past question in past.

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The Talwaar gathra is a special made gathra which is used for talwaars. These gathras have elegant camo patterns embedded into the gathra. There is also a string made from the same material which goes through a talwaar handle to make it more secure.


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What's Going on With the Missouri Senate Race?
Some have raised questions about GOP candidate Josh Hawley's campaign
Posted Feb 5, 2018 8:25 PM
Bridget Bowman
@bridgetbhc
Potential ballot confusion complicates California special election for Katie Hill's seat Democrats try to expand House battlefield by targeting six more districts Liz Cheney is not running for Senate in Wyoming
Missouri Rep. Ann Wagner has reportedly been asked to reconsider her decision not to run for Senate. (Bill Clark/CQ Roll Call file photo)
Missouri is playing host to one of the year's most competitive Senate races, and Attorney General Josh Hawley is supposed to be among the top Republican recruits. But some Republicans from the Show-Me State are starting to raise questions about his campaign's performance so far.
Republicans are still optimistic about their chances of defeating Democratic Sen. Claire McCaskill in a state President Donald Trump won by 20 points. And they're generally still confident in Hawley, who garnered more votes than Trump in his run for attorney general in 2016.
"He won his first statewide race handily," Missouri Sen. GOP Roy Blunt said Monday evening. "I think he's a good candidate. I'm not concerned, but it's a tough state and you have to work hard."
Missouri is one of the few states where Republicans had appeared to avoid a costly and divisive primary. But Politico reported Friday that GOP Rep. Ann Wagner had been approached about reconsidering her decision not to run for Senate, raising concerns about whether Republicans were losing faith in Hawley.
In recent days, some Republicans have been questioning Hawley's fundraising and lack of campaign activity in the four months since he officially launched his campaign.
"This is supposed to be the campaign where we righted all the wrongs of Todd Akin and we exorcised all the demons of past campaigns or past attempts to beat Claire McCaskill," one Missouri GOP consultant said. "And now people are wondering, 'Are we really going to blow this again?'"
Avoiding a primary?
Missouri Republicans do not want to repeat the 2012 Senate race, where Rep. Todd Akin won a contested primary. His campaign imploded after he made a controversial comment that "legitimate rape" rarely leads to pregnancy. McCaskill won that race by 16 points.
When Wagner announced she would not run for Senate last July, the attention shifted to Hawley. Some Republicans in the state noted that Wagner stepping aside meant they could avoid the divisive primary of campaigns past.
Former Missouri GOP chairman John Hancock said Wagner had told him she'd been asked to reconsider, but he doubted she would launch a primary challenge against Hawley.
"I don't think a hig- level primary's in anybody's best interest," Hancock said. "I would be very surprised if we ended up with a primary of two major candidates."
Wagner did not acknowledge a reporter who attempted to address her as she walked onto the House floor Monday night.
The news came shortly after reports of Missouri residents being contacted for what appeared to be a poll pitting Wagner against McCaskill. GOP operatives speculated it came from McCaskill's campaign in an attempt to fuel rumors of discontent among Republicans. The senator admitted in her memoir that she helped Akin through the GOP primary since he would be an easier opponent.
It's still not clear where the poll came from. McCaskill's campaign and a source with Wagner's House campaign both said they were not responsible.
The news that Wagner was approached about reconsidering came shortly after Hawley made his own headline-grabbing comments about one of her pet issues — human trafficking.
The Kansas City Star reported last week that Hawley, who has made combating sex trafficking a priority as attorney general, blamed the crime's uptick on the "sexual revolution" of the 1960s and 1970s.
"We have a human trafficking crisis in our state and in this city and in our country because people are willing to purchase women, young women, and treat them like commodities," Hawley said at a private event with pastors in December, according to audio obtained by the Star.
"There is a market for it," Hawley said. "Why is there? Because our culture has completely lost its way. The sexual revolution has led to exploitation of women on a scale that we would never have imagined, never have imagined."
McCaskill and her campaign jumped on the comments as historically inaccurate, pointing out that the "sexual revolution" involved women using birth control.
"Another Todd Akin" was the subject line of fundraising missive from her campaign last Thursday night. "Hawley's comments are ignorant, sexist and just plain backward."
Several Republicans inside and outside the state were not concerned that Hawley's comments would have any lasting effect, given the many social conservatives in the state.
"You will get more Missourians nodding their head to what he had to say … than you will have people disagreeing," said Gregg Keller, a Missouri GOP consultant who is the former executive director of the American Conservative Union.
For some Republicans though, the broader concern was that Hawley was not out on the campaign trail, and didn't have eye-popping fundraising numbers.
Broader concerns?
Hawley consultant Brad Todd dismissed criticisms about the candidate's fundraising and lack of public campaign events.
"There's plenty of time to campaign this year. Voters are not exactly clamoring for more electoral activity," Todd said in an interview Friday afternoon. "He's very active in the job of attorney general. He's mustering the resources to wage a competitive campaign."
Hawley had $1.19 million in cash on hand at the end of the most recent fundraising quarter, which ended on Dec. 31. McCaskill had more than $9 million on hand, according to her campaign.
Hawley's campaign noted he raised $958,000 in the last quarter, more than other Senate challengers. At the same point last cycle, Missouri Democratic Senate candidate Jason Kander had raised $870,000 with nearly $2.1 million in the bank, though he had been in the race for several more months then.
Some Republicans said money would not be a problem in the top-tier Senate race.
"No one is going to lose this Missouri Senate race for lack of funds," Keller said.
Billionaire Richard Uihlein has already donated $2 million to Club for Growth Action Missouri, a super PAC backing Hawley.
Missouri Treasurer Eric Schmitt is the honorary chairman of another pro-Hawley super PAC, Missouri Rising Action. The group did not raise any funds in 2017, according to campaign finance documents.
"Josh's campaign is off to a great start and we see the enthusiasm building on the ground here in Missouri," Schmitt said in a statement.
But Hawley's personal campaign numbers did raise some eyebrows among Show-Me State Republicans.
"I think people were able to explain away the lack of activity with the assumption that he was raising big-time dough," a GOP consultant in Missouri said Friday. "When the big-time dough didn't happen … this week has been kind of when everybody is starting to freak out."
Hawley has not held any public campaign events since announcing his run in October, prompting Missouri Democrats to launch the website hidinghawley.com. Todd said Hawley has been active in public, holding events in his official capacity as attorney general.
"Voters think campaigns are too long as it is," Todd said. "We're never going to be all politics, all the time like Claire."
McCaskill has been making the rounds in the state, holding 50 town hall meetings last year.
Missouri Democratic operative Jack Cardetti, who worked on McCaskill's 2012 campaign, said her retail politics skills help her connect with voters.
Relating to voters, Cardetti said, "is what often puts her over the top in these elections."
"Josh Hawley can't do that," he said. "And furthermore Josh Hawley isn't even attempting to do that right now."
Some rumors have been circulating among Missouri Republicans that Hawley may not have been active yet because he was having second thoughts about running.
Todd dismissed such discussions as "nonsense."
"It's a joke," Todd said.
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Topics: 2018 at-the-races democrats elections newsletter-out newsletters politics republicans senate Ann Wagner Campaign Finance Campaigns Claire McCaskill conservatives democrats Donald J. Trump Elections Executive Branch House Kansas Missouri polling Republicans Roy Blunt Senate super pacs wage POLI

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text:
The latest medical research on Oral & Maxillofacial Surgery
The research magnet gathers the latest research from around the web, based on your specialty area. Below you will find a sample of some of the most recent articles from reputable medical journals about oral & maxillofacial surgery gathered by our medical AI research bot.
Framework for Training in Minimally Invasive Pancreatic Surgery: An International Delphi Consensus Study.
Journal of the
Previous reports suggest that structured training in minimally invasive pancreatic surgery (MIPS) can ensure a safe implementation into standard practice. Although some training programs have been constructed, worldwide consensus on fundamental items of these training programs is lacking. This study aimed to determine items for a structured MIPS training program using the Delphi consensus methodology.
The study process consisted of 2 Delphi rounds among international experts in MIPS, identified by a literature review. The study committee developed a list of items for 3 key domains of MIPS training: (1) framework, (2) centers and surgeons eligible for training, and (3) surgeons eligible as proctor. The experts rated these items on a scale from 1 (not important) to 5 (very important). A Cronbach's α of 0.70 or greater was defined as the cut-off value to achieve consensus. Each item that achieved 80% or greater of expert votes was considered as fundamental for a training program in MIPS.
Both Delphi study rounds were completed by all invited experts in MIPS, with a median experience of 20 years in MIPS. Experts included surgeons from 31 cities in 13 countries across 4 continents. Consensus was reached on 38 fundamental items for the framework of training (16 of 35 items, Cronbach's α = 0.72), centers and surgeons eligible for training (19 of 30 items, Cronbach's α = 0.87), and surgeons eligible as proctor (3 of 10 items, Cronbach's α = 0.89). Center eligibility for MIPS included a minimum annual volume of 10 distal pancreatectomies and 50 pancreatoduodenectomies.
Consensus among worldwide experts in MIPS was reached on fundamental items for the framework of training and criteria for participating surgeons and centers. These items act as a guideline and intend to improve training, proctoring, and safe worldwide dissemination of MIPS.
Broad vs Narrow Spectrum Antibiotics in Common Bile Duct Stones: A Post Hoc Analysis of an Eastern Association for the Surgery of Trauma Multicenter Study.
Antimicrobial guidance for common bile duct stones during the perioperative period is limited. We sought to examine the effect of broad-spectrum (BS) vs narrow-spectrum (NS) antibiotics on surgical site infections (SSIs) in patients with common bile duct stones undergoing same-admission cholecystectomy.
We performed a post hoc analysis of a prospective, observational, multicenter study of patients undergoing same-admission cholecystectomy for choledocholithiasis and/or acute biliary pancreatitis between 2016 and 2019. We excluded patients with cholangitis, perforated cholecystitis, and nonbiliary infections on admission. Patients were divided based on receipt of BS or NS antibiotics. Our primary outcome was the incidence of SSIs, and secondary outcomes included hospital length of stay, acute kidney injury (AKI), and 30-day readmission for SSI.
The cohort had 891 patients: 51.7% (n= 461) received BS antibiotics and 48.3% (n = 430) received NS antibiotics. Overall antibiotic duration was longer in the BS group than in the NS group (6 vs 4 d, p = 0.01); however, there was no difference in rates of SSI (0.9% vs 0.5%, p = 0.7) or 30-day readmission for SSI (1.1% vs 1.2%, p = 1.0). Hospital length of stay was significantly longer in the BS group (p < 0.001) as were rates of AKI (5% vs 1.4%, p = 0.001). On multivariable regression, BS antibiotic use was a risk factor for AKI (adjusted odds ratio 2.8, 95% CI 1.16 to 7.82, p = 0.02).
The incidence of SSI and 30-day readmission for SSI was similar between antibiotic groups. However, BS antibiotic use was associated with a longer hospitalization and greater likelihood of AKI.
Impedance Planimetry (Endoflip) and Ideal Distensibility Ranges for Optimal Outcomes after Nissen and Toupet Fundoplication.
Previous research has shown that impedance planimetry-based functional lumen imaging probe (FLIP) measurements are associated with patient-reported outcomes after laparoscopic antireflux surgery. We hypothesize that Nissen and Toupet fundoplications have different ideal FLIP profiles, such as distensibility.
A retrospective review of a prospectively maintained quality database was performed. Patients who had FLIP measurements during fundoplications between 2013 and 2021 were included. Reflux Symptom Index, Gastroesophageal Reflux Disease-Health Related Quality of Life Questionnaire, and dysphagia score were collected for up to 2 years postoperatively. The Wilcoxon rank-sum test was used to compare FLIP measurements vs outcomes.
Two hundred fifty patients (171 Toupet, 79 Nissen) were analyzed. Distensibility ranges were categorized as tight, ideal, or loose. The ideal distensibility index range of Toupet patients with the 30- and 40-mL balloon fills were 2.6 to 3.7 mm2/mmHg. This range was associated with less dysphagia at 1 year compared with the tight group (p = 0.02). For Nissen patients, the 30- and 40-mL ideal threshold was a distensibility index of ≥2.2 mm2/mmHg. Patients with distensibility exceeding this threshold had a better quality of life than the tight group, reporting better Gastroesophageal Reflux Disease-Health Related Quality of Life Questionnaire (p = 0.02) and lower dysphagia scores (p = 0.01) at 2 years.
Impedance planimetry revealed different ideal distensibility ranges after Toupet and Nissen fundoplications that are associated with improved patient-reported outcomes, suggesting that intraoperative FLIP has the potential to tailor fundoplication.
Financial Vulnerability of American College of Surgeons-Verified Trauma Centers: A Statewide Analysis.
Although trauma centers represent an integral part of healthcare in the US, characterization of their financial vulnerability has not been reported. We sought to characterize the financial health and vulnerability among California trauma centers and identify factors associated with high and low vulnerability.
The RAND Hospital Data financial dataset was used to evaluate all American College of Surgeons (ACS)-verified trauma centers in California. Financial vulnerability of each center was calculated using 6 metrics to calculate a composite Financial Vulnerability Score (FVS). Tertiles of the FVS were generated to classify trauma centers as high, medium, or low financial vulnerability. Hospital characteristics were also analyzed and compared.
Forty-seven ACS trauma centers were identified. Nine were Level I, 27 were Level II, and 8 were Level III. Level I centers encompassed the greatest proportion of the high FVS tier (44%), whereas Level II and III centers were the most likely to be in the middle and lower tiers, respectively (44%; 63%). Lower FVS centers had greater asset:liability ratios, operating margins, and days cash on hand compared with the 2 higher tiers, whereas high FVS centers showed a greater proportion of uncompensated care, outpatient share rates, outpatient surgeries, and longer days in net accounts. Lower FVS centers were more likely to be teaching hospitals and members of a larger corporate entity.
Many ACS trauma centers are at moderate/high risk for financial vulnerability and disparate impacts of stressor events, and the FVS may represent a novel metric that could be used at the local or statewide level.
Effect of Function-Based Approach to Nontraumatic Major Lower Extremity Amputation on 5-Year Mortality.
Five-year mortality rates after lower extremity amputation in the chronic wound population have long been regarded as high and inevitable. We theorize that function-based surgical technique and multidisciplinary care improve mortality and assess our institution's mortality rates after major lower extremity amputation (MLEA).
We performed a retrospective review of patients who underwent primary nontraumatic MLEA at our institution from 2010 to 2013. Major amputations included below knee amputation, through knee amputation, and above knee amputation. Our function-based surgical approach to MLEA is guided by 4 tenets: (1) optimization of limb biomechanics, (2) maximal soft tissue preservation, (3) multidisciplinary team approach, and (4) addressing nerves during primary amputation to prevent postamputation pain. Kaplan-Meier analysis and Cox regression were performed to estimate cumulative 5-year mortality and to identify predictors of 5-year mortality, respectively.
A total of 188 patients underwent MLEA. Median Charlson Comorbidity Index was 4. Estimated 5-year mortality was 40% overall and 43% for diabetic patients. When stratified by amputation level, 5-year mortalities were 36.3% for below knee amputation, 60.9% for through knee amputation, and 44.0% for above knee amputation. Charlson Comorbidity Index (hazard ratio 1.24, p < 0.001) and end-stage renal disease (hazard ratio 3.38, p < 0.001) were the strongest predictors of 5-year mortality.
We demonstrate the lowest mortality rate reported for MLEA. Improved functional and mortality outcomes can be achieved with a function-based surgical approach to MLEA and close follow-up by a multidisciplinary team. Future studies, using standardized reporting of mortality data and incorporating patient-reported outcomes, are warranted to correlate return to function and mortality.
Effect of Background Music in the Operating Room on Surgical Outcomes: A Prospective Single-Blinded Case-Control Study.
The effect of playing background music on surgical outcomes has been controversial. This prospective case-control study aims to evaluate the impact of music tempo in general surgical settings.
Six hundred consecutive patients with nonmetastatic breast cancer receiving breast cancer surgery have been recruited since April 2017. Patients were then assigned to 3 arms in consecutive order. The surgeon operated without music in study arm A; the surgeon operated with slow music in study arm B; and in study arm C, the surgeon operated with fast background music. Patients' clinical records were reviewed by an independent blinded assessor.
Baseline demographic data were comparable among the 3 study arms. Seven (3.5%) patients from study arm A developed minor complications (Clavien-Dindo class I and II); none developed major complications (Clavien-Dindo class III or above). Six (3.0%) patients from study arm B and C, respectively (slow/fast music groups), developed minor complications; none developed a major complication. Mean blood loss was also similar among the 3 study arms (5.1, 5.1, and 5.2 mL, respectively; p > 0.05). Operating time was significantly shorter in study arm C: 115 minutes (90-145), compared with 125 minutes (100-160) in study arm A (p < 0.0001) and 120 minutes (95-155) in study arm B (p = 0.0024). After a median follow-up of 40 months (3-56), 40 months (3-56), and 39.5 months (3-56), the local recurrence rates were 1.5%, 1%, and 1%, respectively (p > 0.05).
Playing music in the operating room is safe in general surgical settings in experienced hands.
Dexamethasone for Postoperative Nausea and Vomiting in Papillary Thyroid Carcinoma Patients: A Randomized Clinical Trial.
Postoperative nausea and vomiting (PONV) frequently occur after thyroidectomy. Previous studies have investigated the effects of preoperative dexamethasone for alleviating PONV in various cancers, but studies focused on papillary thyroid carcinoma (PTC) were limited. This study aimed to determine the efficacy of a single preoperative dose of dexamethasone to prevent PONV in patients with PTC.
This single-center, parallel-group, double-blind, placebo-controlled clinical trial was conducted on patients with PTC in West China Hospital. Patients were randomized 1:1 into Group Dex (preoperative 8-mg dexamethasone) or Group Control (0.9% NaCl as control). The primary outcome was the incidence and severity of PONV. The secondary outcomes included postoperative pain, vocal dysfunction, and adverse events.
Six hundred participants were recruited and randomized. The total incidence of PONV was 33.3% (200 of 600 patients; 95% CI, 29.6-37.1). In the intention-to-treat analysis, PONV occurred in 81 of 300 patients (27.0%; 95% CI, 21.9-32.1) in Group Dex and in 119 of 300 patients (39.7%; 95% CI, 34.1-45.2) in Group Control (p = 0.001), and the absolute risk reduction was 12.7% (95% CI, 5.1-20.0). Patients in Group Dex reported fewer antiemetic requirements than those in Group Control (p = 0.004). Multivariate analysis indicated that dexamethasone administration (OR = 0.546; 95% CI, 0.383-0.777; p = 0.001) was associated with a reduced rate of PONV. Dexamethasone treatment also contributed to alleviating postoperative pain and improving subjective vocal dysfunction, with no increase in adverse events.
A single dose of dexamethasone is effective and safe for preventing PONV in PTC patients.
Role of Transfusion Volume and Transfusion Rate as Markers of Futility During Ultramassive Blood Transfusion in Trauma.
Using a large national database, we evaluated the relationship between RBC transfusion volume, RBC transfusion rate, and in-hospital mortality to explore the presence of a futility threshold in trauma patients receiving ultramassive blood transfusion.
The ACS-TQIP 2013 to 2018 database was analyzed. Adult patients who received ultramassive blood transfusion (≥20 units of RBC/24 hours) were included. RBC transfusion volume and rate were captured at the only 2 time points available in TQIP (4 hours and 24 hours), or time of death, whichever came first.
Among 5,135 patients analyzed, in-hospital mortality rate was 62.1% (n = 3,190), and 4-hour and 24-hour mortality rates were 17.53% (n = 900) and 42.41% (n = 2,178), respectively. RBC transfusion volumes at 4 hours (area under the receiver operating characteristic curve [AUROC] 0.59 [95% CI 0.57 to 0.60]) and 24 hours (AUROC 0.59 [95% CI 0.57 to 0.60]) had low discriminatory ability for mortality and were inconclusive for futility. Mean RBC transfusion rates calculated within 4 hours (AUROC 0.65 [95% CI 0.63 to 0.66]) and 24 hours (AUROC 0.85 [95% CI 0.84 to 0.86]) had higher discriminatory ability than RBC transfusion volume. A futility threshold was not found for the mean RBC transfusion rate calculated within 4 hours. All patients with a final mean RBC transfusion rate of ≥7 U/h calculated within 24 hours of arrival experienced in-hospital death (n = 1,326); the observed maximum length of survival for these patients during the first 24 hours ranged from 24 hours for a rate of 7 U/h to 4.5 hours for rates ≥21 U/h.
RBC transfusion volume within 4 or 24 hours and mean RBC transfusion rate within 4 hours were not markers of futility. The observed maximum length of survival per mean RBC transfusion rate could inform resuscitation efforts in trauma patients receiving ongoing transfusion between 4 and 24 hours.
Deep Neural Network for the Prediction of KRAS Genotype in Rectal Cancer.
KRAS mutation can alter the treatment plan after resection of colorectal cancer. Despite its importance, the KRAS status of several patients remains unchecked because of the high cost and limited resources. This study developed a deep neural network (DNN) to predict the KRAS genotype using hematoxylin and eosin (H&E)-stained histopathological images.
Three DNNs were created (KRAS_Mob, KRAS_Shuff, and KRAS_Ince) using the structural backbone of the MobileNet, ShuffleNet, and Inception networks, respectively. The Cancer Genome Atlas was screened to extract 49,684 image tiles that were used for deep learning and internal validation. An independent cohort of 43,032 image tiles was used for external validation. The performance was compared with humans, and a virtual cost-saving analysis was done.
The KRAS_Mob network (area under the receiver operating curve [AUC] 0.8, 95% CI 0.71 to 0.89) was the best-performing model for predicting the KRAS genotype, followed by the KRAS_Shuff (AUC 0.73, 95% CI 0.62 to 0.84) and KRAS_Ince (AUC 0.71, 95% CI 0.6 to 0.82) networks. Combing the KRAS_Mob and KRAS_Shuff networks as a double prediction approach showed improved performance. KRAS_Mob network accuracy surpassed that of two independent pathologists (AUC 0.79 [95% CI 0.64 to 0.93], 0.51 [95% CI 0.34 to 0.69], and 0.51 (95% CI 0.34 to 0.69]; p < 0.001 for all comparisons).
The DNN has the potential to predict the KRAS genotype directly from H&E-stained histopathological slide images. As an algorithmic screening method to prioritize patients for laboratory confirmation, such a model might possibly reduce the number of patients screened, resulting in significant test-related time and economic savings.
Risk Reduction Strategy to Decrease Incidence of Retained Surgical Items.
Retained surgical items (RSIs) are rare but serious events associated with significant morbidity and costs. We assessed the effectiveness of radiofrequency (RF) detection technology and Team Strategies and Tools to Enhance Performance and Patient Safety (TeamSTEPPS) in reducing the incidence of RSIs.
All RSIs reported to the New York Patient Occurrence Reporting and Tracking System at five large urban teaching hospitals from 2007 to 2017 were analyzed. In 2012, TeamSTEPPS training was provided to all perioperative staff at each site, and use of RF detection became required in all procedures. The incidence of events before and after the interventions were compared using odds ratios.
A total of 997,237 operative procedures were analyzed. After the interventions, the incidence of RSIs decreased from 11.66 to 5.80 events per 100,000 operations (odds ratio [OR] [95% CI] = 0.50 [0.32 to 0.78]). The frequency of RSIs involving RF-detectable items decreased from 5.21 to 1.35 events per 100,000 operations (OR [95% CI] = 0.26 [0.11 to 0.60]). The difference in RSIs involving non-RF-detectable surgical items was not statistically significant.
The incidence of RSIs was significantly lower during the time period after implementing RF detection technology and after TeamSTEPPS training, primarily driven by a decrease in retained RF-detectable items. RF detection technology may be worth pursuing for hospitals looking to decrease RSI frequency. The benefit of TeamSTEPPS training alone may not result in a reduction of RSIs.
Night Radiology Coverage for Trauma: Residents, Teleradiology, or Both?
Overnight radiology coverage for trauma patients is often addressed with a combination of on-call radiology residents (RR) and a teleradiology service; however, the accuracy of these 2 readers has not been studied for trauma. We aimed to compare the accuracy of RR versus teleradiologist interpretations of CT scans for trauma patients.
A retrospective analysis (March 2019 through May 2020) of trauma patients presenting to a single American College of Surgeons Level I trauma center was performed. Patients whose CT scans were performed between 10 pm to 8 am were included, because their scans were interpreted by both a RR and teleradiologist. Interpretations were compared with the final attending faculty radiologist's interpretation and graded for accuracy based on the RADPEER scoring system. Discrepancies were characterized as traumatic injury or incidental findings and missed findings or overcalls. Turnaround time was also compared.
A total of 1,053 patients and 8,226 interpretations were included. Compared with teleradiologists, RR had a lower discrepancy (7.7% vs 9.0%, p = 0.026) and major discrepancy rate (3.8% vs 5.2%, p = 0.003). Among major discrepancies, RR had a lower rate of traumatic injury discrepancies (3.2% vs 4.4%, p = 0.004) and missed findings (3.4% vs 5.1%, p < 0.001), but a higher rate of overcalls (0.5% vs 0.1%, p < 0.001) compared with teleradiologists. The mean turnaround time was shorter for RR (51.3 vs 78.8 minutes, p < 0.001). The combination of both RR and teleradiologist interpretations had a lower overall discrepancy rate than RR (5.0% vs 7.7%, p < 0.001).
This study identified lower discrepancy rates and a faster turnaround time by RR compared with teleradiologists for trauma CT studies. The combination of both interpreters had an even lower discrepancy rate, suggesting this combination is optimal when an in-house attending radiologist is not available.
Association Between Statewide Medicaid Opioid Policy and Postoperative Opioid Prescribing among Surgeons at a Large Safety-Net Hospital.
Restrictive state and payer policies may be effective in reducing opioid prescribing by surgeons, but their impact has not been well studied. In 2017, Washington Medicaid implemented an opiod prescribing limit of 42 pills, prompting a large regional safety-net hospital to implement a decision support intervention in response. We aimed to evaluate the effects on surgeons' prescribing.
We retrospectively studied postoperative opioid prescribing (quantity of pills prescribed at discharge) to opioid-naïve surgical patients at a regional safety-net hospital from 2016 to 2020. We investigated associations between the policy and opioid prescribing by using interrupted time series analysis, adjusting for clinical and sociodemographic factors.
A total of 12,799 surgical encounters involving opioid-naïve patients (59% male, mean age 52) were analyzed. Opioids were prescribed for 75%. From 2016 to 2020, the mean prescribed opioid quantity decreased from 36 pills to 17 pills. In interrupted time series analysis, the Medicaid policy implementation was associated with an immediate change of -8.4 pills (95% CI -12 to -4.7; p < 0.001) per prescription and a subsequent rate of decrease similar to that prepolicy. In a comparison of changes between patients insured through Medicaid vs Medicare, Medicaid patients had an immediate change of -9.8 pills (95% CI -19 to -0.76; p = 0.03) after policy implementation and continued decreases similar to those prepolicy. No immediate or subsequent policy-related changes were observed among Medicare patients.
In a large regional safety-net institution, postoperative opioid prescriptions decreased in size over time, with immediate changes associated with a state Medicaid policy and corresponding decision support intervention. These findings pose implications for surgeons, hospital leaders, and payers seeking to address opioid use via judicious prescribing.


text:
Folonzo är en ort i Burkina Faso.   Den ligger i regionen Cascades, i den sydvästra delen av landet,  km sydväst om huvudstaden Ouagadougou. Folonzo ligger  meter över havet och antalet invånare är .

Terrängen runt Folonzo är platt, och sluttar österut. Den högsta punkten i närheten är  meter över havet,  km väster om Folonzo. Runt Folonzo är det glesbefolkat, med  invånare per kvadratkilometer.. Närmaste större samhälle är Wangolodougou,  km nordväst om Folonzo.

Omgivningarna runt Folonzo är huvudsakligen savann.  Savannklimat råder i trakten. Årsmedeltemperaturen i trakten är  °C. Den varmaste månaden är mars, då medeltemperaturen är  °C, och den kallaste är augusti, med  °C. Genomsnittlig årsnederbörd är  millimeter. Den regnigaste månaden är september, med i genomsnitt  mm nederbörd, och den torraste är december, med  mm nederbörd.

Kommentarer

Källor

Orter i Cascades, Burkina Faso

redpajama_set_name: RedPajamaWikipedia


FEA-Opt Technology announced that, Giant Bicycles and one major ODM of composite bike frame at Taiwan have all adopted SmartDO as the solver and integration platform for design optimization and automation.
Founded in 1972 at Taiwan, Giant Manufacturing Co. Ltd. (commonly known as Giant Bicycles), is recognized as the world's largest bicycle manufacturer with facilities in Taiwan, Netherlands, and China. Today Giant has sales in over 50 countries, in over 12,000 retail stores.
With MSC Software as its major CAE system, Giant needs a platform to integrate and automate all the different in-house codes and packages. In addition, it also needs a powerful tool to achieve design optimization and further improve its already leading edge products. After intensive evaluation and study, Giant adopted SmartDO in 2013 as its major design optimization and engineering process integration platform.
"SmartDO has always been able to provide direct and definite return of investment on the customer's existence CAE system." said Dr. Shen-Yeh Chen of FEA-Opt Technology. "With Giant and one major ODM of composite bikes (who preferred not to be named) joining our customers group, it means SmartDO has established its reputation in the bikes industry, among others."


text:
Belinda Adams-Pearce Interview
1. How long have you been making art?
Well, in the words of Roxie Hart [Chicago] "I'm older than I ever intended to be" so to say that I've been painting all my adult life equates to an awfully long time! But truly I have painted for my own recreational/therapeutic purposes off and on for umpteen years, but it's only been in the last five or so that I've had the temerity to style myself as an artist and make art for public view.
2. What genre best describes what you do?
I've not made a conscious effort to follow, or bring myself within, a particular artistic category or group, so I'm reticent to claim that a specific genre applies; generally my current works are more representational than pictorial, not wholly expressionistic, but slightly. Oh dear, that doesn't sound very helpful at being descriptive, may I leave it to the viewer to determine?
3. How has your artwork evolved since you began?
Seascapes are my recurring theme; perhaps a subliminal escape from hectic day-to-day life to the water's edge! My scenes were initially depicted by fluid sweeping bands of colour, since I found the calm serenity in broad brush strokes to be the antithesis of my professional life. However, over the years I have refined that fluidity and concentrated more on endeavouring to capture atmosphere and mood rather than a scenic interpretation; I believe my artwork is still evolving in this respect and as I am unlikely to ever be wholly content with the result it will always be 'work in progress.'
4. Is there a medium or technique that you have yet to try but would like to?
I work in mixed medium, oil and acrylic, but I often envisage many of my seascapes as watercolours; in fact I think they would be much more moody and atmospheric in watercolour but I guess I play safe and stick with my tried and tested techniques. However, one day I would like to experiment.
5. What would your ideal solo exhibition be like and where would it be held?
Ah, I can answer with little or no hesitation, because of the subject matter of my artwork my preference would be to exhibit somewhere beside the sea. A high and airy space with views out to the horizon and my canvasses hung on white-washed walls. Brighton is a favourite, it has such character, but the venue would have to be bright and spacious and I envisage sunshine flooding the gallery, illuminating my canvasses to best effect. Hmmm perhaps I should opt for Barcelona instead of Brighton, for more reliable weather.
6. What do you like most about the art world?
I guess this is an obvious, and probably popular, response.....the freedom of expression, and the knowledge that there is acceptability in all forms of innovation.
7. If you could change anything about the London art scene, what would it be?
An ability to make it a more financially viable world for the emerging artist would be my desired change; I am indebted to the New Artist Fair for an affordable opportunity to exhibit and sneak into that world, but such options for self-advancement are few for the struggling artist.
8. What or who inspires you to make art?
Horizons. I immerse myself in replicating the peaceful wistfulness of gazing out to the blue yonder. But it's not the sea itself that captivates me, rather the effect of the water on the sky above and that point at which the two converge. I am a member of The Cloud Appreciation Society and am passionate about, obsessed even, with skies: the shades, tones, and diversity of patterns created by atmospheric optical phenomena.
9. Where did you sell your first painting and how did it feel?
Having amassed a variety of canvasses over the years, I was encouraged by friends and family to share them with a wider public; to this end a local cafe owner agreed to hang a few by way of decoration, but each bearing my contact details on a tag in case of interest. Unexpectedly I received a call within a couple of weeks, and met the caller at the cafe; she was a lady in her 90s who initially purchased 2 canvasses. That alone was a sheer delight, but I subsequently learned that she is a long-standing and knowledgeable patron of the arts, an experienced and avid collector of originals only, and I have since had the ultimate privilege of seeing my pieces adorning her walls alongside works by artists of great renown.
10. What are your plans for the New Artist Fair in March?
I shall be exhibiting my latest 'Horizons' collection; it is a joy to be able to show and share my artwork with a wider public, and I am looking forward to the camaraderie of the fellow exhibitors, and the professionalism of the organizers, that I experienced at the 2012 Brick Lane New Artist Fair.
bap40kings@aol.com
https://twitter.com/artycrazyB_AP


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TUCSON, Ariz.—High Throughput Genomics Inc. (HTG), a player in the personalized medicine arena and provider of the quantitative Nuclease Protection Assay (qNPAT) system, recently announced a collaboration agreement with researchers at Harvard Catalyst Laboratory for Innovative Translational Technologies (HC-LITT) at Harvard Medical School.
Under the terms of the agreement, HTG and HC-LITT will work on a novel microRNA (miRNA) biogenesis assay that can measure expression of pre-miRNA, mature-miRNAs and regulated RNA using HTG's qNPAT technology.
"There are two things happening with the Harvard Catalyst Lab deal, the first being that they are doing validation studies on microRNA and qNPA-based arrays and applying those to their internal programs as we go out and try to get those arrays to market," says Dr. Bruce E. Seligmann, founder and CSO for HTG. "Then they will be doing the same thing with mid-density miRNA arrays; they will use them internally, and we will work to bring them to market for other researchers and drug developers."
What HTG will market will be the "next generation" arrays rather than the "beta" arrays HC-LITT is starting off with, Seligmann notes.
"They are, in a sense, a test lab for us," he explains. "They validate the arrays, but they also get to be early adopters and get early access to our development technology. They benefit from access to us, and at the same time, they help identify issues so that we can correct the arrays before going to market with them."
Researchers at HC-LITT are investigating the implications of differential microRNA expression in human diseases. HC-LITT will utilize HTG's technology to evaluate regulation of miRNA biogenesis by established oncogenic cell signaling pathways to develop novel diagnostic markers and therapeutic targets for the molecular characterization and treatment of cancer.
"We selected HTG's technology due to the high precision and sensitivity of the product platform," says Winston Patrick Kuo, director of HC-LITT. "I'm looking forward to utilizing HTG's gene expression assay technology and imagers for HC-LITT's research initiatives."


text:
Good news for Angela MerkelImage: AP
Path Cleared for German Federalism Reform
DW staff (tkw)
After years of debate, Germany's federal and state governments have agreed on plans to reform their individual responsibilities, thus paving the way for a more transparent and efficient means of government.
https://p.dw.com/p/808b
Thursday's agreement between state premiers, government ministers and the leaders of the two coalition partners is seen as something of a coup for Angela Merkel, who has given the federalism reform top priority on her grand coalition agenda.
At the heart of the reforms, the biggest constitutional change since 1949, is a redistribution of power aimed at preventing paralysis in the process of passing new legislation. As it stands, two thirds of all legislative bills have to be approved by both houses of parliament, and while that is not a problem for the grand coalition, it often led to law-making difficulties for the previous government of former Chancellor Gerhard Schröder.
The upper house of parliament, the Bundesrat, frequently adopted an obstructive role, which it had the power to do. Under the new reforms, more than 60 percent of new legislation will be eligible to be passed without endorsement from the upper house, greatly speeding up Germany's law-making procedures.
Swapping power
Bavarian Premier Edmund StoiberImage: AP
The reform will see the 16 federal states give up some of their voting rights in the Bundesrat. In return, they will be granted greater responsibility in other fields, such as environmental issues, educational policies and salaries for civil servants. But some politicians have already expressed a resistance to having big policy areas, such as education, taken out of federal hands.
The state premier for Bavaria, Edmund Stoiber, however, echoed the majority voice following Thursday's session. He said he was "very satisfied" with the outcome, which he said means Germany will be able to be quicker and more flexible in its decision-making.
Merkel Stresses Urgent Need for Federalism Reform
German chancellor Angela Merkel has reiterated hopes that the country's federal system will be speedily tackled without any further delays. (Dec. 22, 2005)
The Crunch Issues
Almost two months after an inconclusive election, Germany's major parties have forged a coalition deal for a four-year term under Chancellor Angela Merkel. Here are the main points. (Nov. 23, 2005)
Federalism Weakens Germany in Europe
Experts are warning that without reform to its federal system, Germany will be both politically and economically disadvantaged on the international stage. (Oct. 22, 2005)


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"Shout for joy in the Lord, O you righteous! Praise befits the upright. Give thanks to the Lord with the lyre; make melody to him with the harp of ten strings! Sing to him a new song; play skillfully on the strings, with loud shouts."
"Let the word of Christ dwell in you richly, teaching and admonishing one another in all wisdom, singing psalms and hymns and spiritual songs, with thankfulness in your hearts to God."
"And they were singing a new song before the throne and before the four living creatures and before the elders. No one could learn that song except the 144,000 who had been redeemed from the earth. "
that I felt compelled to make it more widely available. Hence this humble web site.
The CD is FREE of CHARGE - I only request enough to cover post & packing etc.
My prayer and hope is that you will also be blessed in some way and that you will indeed feel 'Closer 2 God'.
If you do like what you hear, please pass my website address on to others.
However, you can hear a clip from every track below, so see what you think.
Equipement used:- Roland Digital Stage Piano, laptop computer running Audacity software.
CD total playing time over 73 mins.
plus an email to me detailing your order and delivery address etc. - thank you.
Thank you once again for making the CD and blessing people in many different ways through its contents."
I needed some inspiration.....remembered a CD Nigel had kindly passed on to me and, such a blessing to have the music played in the special style which flows so easily.
Many familiar tunes gave my efforts such a lift. Thank you, Nigel; may this gifted ministry continue and be a source of encouragement wherever it is shared."
"I just want to say a huge thank you for your wonderful CD you gave me a while ago. It has blessed me more than you realise. Gods timing is perfect as I was suffering from tinnitus. Your CD calmed my spirit and helped me focus less on my head noise and more on being still in the Lord.
Be blessed and encouraged and I pray that everyone who hears this CD will be refreshed and renewed by the Holy Spirit of our Lord and Saviour."
"This CD benefits greatly from the personal improvisation and interpretation given by Nigel - with the gift of piano playing the Lord has blessed him with - Nigel takes one with him, in each track, into a personal intimate space with Jesus.
The additional spoken word in some of the pieces adds even more to the blessing this CD brings to the listener.
For those times - when one needs to bathe in the simple joy of music and fulfilment of love of the Lord - I can wholly recommend this CD Closer 2 God."


text:
Q: "Can't reach this page" when browsing localhost on Team Foundation Server website host I am using IIS10 and TFS2018, running on Windows Server 2019.
What I am ultimately trying to do is set the attachment size, which would use this URL:
http://localhost:8080/tfs/MyTFSProjectCollection/WorkItemTracking/v1.0/ConfigurationSettingsService.asmx?op=SetMaxAttachmentSize
This doesn't work, however.
The actual website is up - it's running in IIS and I can get to the real user-facing data from any workstation on the network.  I'm not able to access it from the IIS / TFS host, however, either by that specific URL or going into IIS and trying to "Browse" the website through the IIS console.  Unfortunately this is the only way to set the max file size from what I can tell.
I only get:
Can't reach this page
•Make sure the web address is correct
•Search for this site on Bing
•Refresh the page
The website in question uses SSL, so out of curiosity I tried https:// version of that URL, as well as even a variant with both https:// and :443.  I've also just tried leaving the port off, to no avail.
The host uses a proxy, which I've disabled to no avail (it is set to bypass said proxy for local addresses, and even has explicit exceptions for localhost and its own IP address besides).  This doesn't help.
What could be preventing me from browsing the website itself on its own host if I'm able to access it elsewhere?  There isn't a whole lot of information to try and troubleshoot this with that I'm able to find, and the server itself is not forthcoming.

A: There were several things that needed to happen in order to fix this:

*

*Configure Loopback settings correctly:  https://docs.microsoft.com/en-us/troubleshoot/windows-server/networking/accessing-server-locally-with-fqdn-cname-alias-denied

*Disable "Enhanced Protection Mode" on Internet Explorer.

*Configure Group Policy to allow users to bypass bad certificates.
In my case, #3 was required because the machine cert has a Principal Name that matches the machine's hostname, but the website name is slightly different and thus it thinks it's wrong.
Additionally, Microsoft Guidance claims you can access the site with localhost as the hostname, but this never worked - I was only able to get this to work when using the website's actual name.


CED Member and CED Life Science Conference 2013 presenting company TearScience®, Inc., a privately held medical device company, today announced that it has secured up to $70 million in funding from HealthCare Royalty Partners to fully implement the company's commercialization efforts and establish the TearScience® system as the "Standard of Care" for evaporative dry eye.
This news comes a month after TearScience® received FDA clearance for the LipiView® Ocular Surface Interferometer.
TearScience® is focused on the worldwide dry eye market with more than 100 million sufferers and 86 percent having evaporative dry eye.
"We are blessed to obtain this funding to build on our commercialization success. Our company had an exceptional first year product launch with TearScience® selling more than 100 systems and effectively treating thousands of dry eye sufferers and proving our commercial business model. HealthCare Royalty Partners' funding and partnership will provide TearScience® the financial resources to build on our success and fully execute on our global commercialization efforts," said Tim Willis, President & CEO of TearScience® in a statement.
"The TearScience® system revolutionizes the eye-care professional's entire approach to evaporative dry eye," commented Gregory B. Brown , M.D., founding managing director at HealthCare Royalty Partners.
More than 23 million Americans suffer from dry eye disease. With the majority (86 percent) suffering from evaporative dry eye, this represents a more than $10 billion market potential in North America.
TearScience® has developed and launched its system to address this market. The system includes the LipiView® Ocular Surface Interferometer and the LipiFlow® Thermal Pulsation System. Evaporative dry eye occurs when Meibomian glands in the eyelids become obstructed and do not secrete the oily lipids needed to keep the water portion of tears from evaporating too quickly.
LipiView measures the absolute thickness of the lipid layer of a dry eye patient's tear film while LipiFlow treats the root cause of evaporative dry eye disease by unblocking obstructed Meibomian glands during an in-office procedure.
The goal of treating evaporative dry eye by unblocking the Meibomian glands is to allow the glands to resume their natural production of lipids required for a healthy tear film and ocular surface.


Bobby Verdugo and Yoli Rios met in high school and soon found themselves leading the historic 1968 walkouts in East Los Angeles, California – a student-led effort to bring education reform to disenfranchised schools with large populations of Hispanic students.
Fifty years later, on a campus more than 2,100 miles away, their monumental husband-and-wife legacy has been honored. The newly named Bobby Verdugo and Yoli Rios Bilingual Mentor and Tutoring Center, in McCreary Hall at Eastern Kentucky University, is helping to shape the next generation of Latino leaders. Hours before they were to deliver a Chautauqua lecture and keynote address for Hispanic Heritage Month at EKU, where more than 450 Latino students are enrolled, Verdugo and Rios were feted during brief ceremonies at the center Thursday, Sept. 27.
The center provides tutoring in languages offered by the Department of Languages, Cultures, and Humanities, including Spanish, French, German and Japanese, and celebrates Latino heritage and culture, providing tutoring and peer mentorship to current and prospective EKU students. Student tutor-mentors are also engaged in community outreach by assisting Latino students and their families with achieving access to higher education.
The facility is graced on one wall by a brightly colored mural painted by Dr. Javier Alvarez-Jaimes, a professor in the Department of Languages, Cultures, and Humanities, with the assistance of the Latino Student Association. The artwork depicts Verdugo flanked by Dolores Huerta, Cesar Chavez and Sylvia Mendez, all icons of Chicano civil rights movement.
The mural served as a fitting backdrop as EKU students, faculty and administrators joined Verdugo and Rios for a succession of photos after the ceremony.
Eastern also boasts an active Latino Student Association.


If you have a Jaguar I-PACE, then you use the CCS plug. Please ensure that you insert the plug properly.
The charge speed is up to 100 kW at our 175 kW fast chargers and 50 kW at our other chargers. In the charge curve below you can see the charge speed of the I-PACE at both chargers. On average the I-PACE charges 100 km in 15 - 30 minutes. At a 175 kW charger the charge speed will slowly drop as of 40%. At a 50 kW charger this happens as of 80%.
The software update for the I-PACE to enable fast charging up to 100 kW is available at the Jaguar dealer since March.
In some cases the car does not release the connector.
To unlock the charging port when the vehicle is locked: Press the unlock button on the smart key twice. Wait 6 seconds for the charging port lock to release.
Another option is the emergency release: For that, please open the bonnet and pull the emergency release ring, adjacent to the charge port. This will allow the charge cable to be removed from the charge port.
For more information, please contact your car dealer.


Materials: High quality linen, Upholstery weight fabric, Washable heavyweight Interfacing, Cotton Lining in complementary striped fabric. Handles in matching fabric.
The straps are 23.5 inches or 60 cms long so the bag can be carried comfortably as a shoulder bag.
The lining and matching handles come in a choice of 2 types of striped fabric - light pink strips or dark pink stripes . Please choose option at checkout.


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DIRITTI GLOBALI – Italian Site
El establecimiento reciente de relaciones diplomáticas entre Nicaragua y China popular
La elección de Argentina, Honduras y Paraguay en el Consejo de Derechos Humanos de Naciones Unidas: breves apuntes
Sudáfrica profundamente "consternada" por decisión de la Unión Africana sobre Israel
Embargo norteamericano contra Cuba: Estados Unidos exhibe nuevamente su soledad
Infinito Gold vs. Costa Rica: breve análisis del laudo arbitral del CIADI
The Sheikh Jarrah Intifada
ECONOMICAL RIGHTS
MAS ALLÁ DEL CORONAVIRUS – NEWSORUND/4
La retraite et le paradis sur terre
Un informe destaca que la banca ética rinde el triple que la tradicional
Ireland "Summer of the Vultures"
Ireland: No Longer Homes – Only (Bank) Assets Now?
Five ways to curb the power of corporations
SanPa. Where did we leave off? Where are we now?
Ireland: Mother & Baby Homes report a whitewash — but Church and State are guilty!
Elections in Euskal Herria and Galicia: Historic, seismic and left!
Sinn Féin set for 12 December Westminster elections
Ireland faces biggest challenge as Brexit becomes reality
Voting for the next President of Ireland
Al conmemorarse los 40 años del asesinato de Viviana Gallardo en Costa Rica
INFORME PRELIMINAR VIOLACION DE DDHH EN COLOMBIA
Naciones Unidas: el voto en favor de mas justicia para las víctimas palestinas
Palestine/Cour Pénale Internationale: la campagne israélienne contre la décision de la Chambre préliminaire
In memory of Sakine Cansiz, Fidan Dogan and Leyla Saylemez
#CoronaCapitalism: Riots, resistance and releases – the Coronavirus and the prison industrial complex
ENVIRONMENTAL RIGHTS
Acuerdo de Escazú: una nueva publicación
La entrada en vigencia del Acuerdo de Escazú: una no celebración teñida de tensión en Costa Rica
De cara a la entrada en vigencia del Acuerdo de Escazú: algunas actividades
El denominado "Pacto de Leticia por la Amazonia": breves apuntes
Crísis diplomática a raíz de los incendios en la Amazonía brasileña
El archipiélago ruso de Nueva Zembla sufre una "invasión" de osos polares por el cambio climático
CULTURE OF LIBERATION
Cuentas Claras 3.0
TALKING PRISON
GR INTERVIEWS
GLOBAL RIGHTS
TALKING PEACE
Global Rights Magazine
Dear Secretary General Guterres, stop Turkey's massacre in Afrin
14 Mar, 2018 by ANF-News
"The Turkish state is denying killing civilians in Afrin. However, in wars the truth is lost first. The three-month-old Miray Ince who was killed in Cizre and three-month-old Diyana Xazî Salih who has been killed in a bombardment in Afrin are the victims of the same silence. If we look at what has happened so far, the Turkish state and FSA's progress towards Afrin may lead to a horrific massacre." HDP MP Faysal Sarıyıldız
HDP MP Faysal Sarıyıldız, – who himself was targeted by Turkish gunfire 2 years ago, as he attempted to help civilian casualties of the Turkish military assault on the Kurdish communities of Northern Kurdistan – has written a letter to the United Nations Secretary General António Manuel de Oliveira Guterres…
An open letter to the United Nations Secretary General António Guterres on the Turkish state's invasion operation against Afrin Canton of Northern Syria:
"The Turkish state's operations against Afrin, initiated on 20 January 2018, is in its 47th day. According to figures given by international human rights organizations at least 250 civilians, mostly women and children, have been killed in bombardments with 600 people wounded. After rising civilian deaths the United Nations decided to declare a 30-day ceasefire on 24 February 2018. Although it is a member of the UN, Turkey has disregarded this decision and continues its bombardment of Afrin with civilian casualties hitting new heights every day. Despite this occupation occurring in front of the world's eyes, the lack of action by the UN is having a detrimental effect on the organization's respectability and reliability. This is being watched with anger by the Kurds and all the peoples of the world.
Mr. Guterres,
We have seen many times in the past that states can be stopped and punished by international organizations that they are a member of. Turkey's Afrin operation has no legitimate grounds. The Turkish state is using UN's article 51 to legitimize its attack. As a matter of fact, there has been no attack against Turkey from Afrin. The local administration in Afrin has stated that an observational delegation can come to Afrin to investigate allegations of Turkish state atrocities. The Turkish state has also not received any permission from the Syrian state to enter its territories. The YPG, who is defending its people in Afrin, is responsible for the defeat of ISIS in Kobani, Raqqa and other parts of Syria.
Erdogan, who possesses the second biggest army in NATO, along with the "Free Syrian Army" is attacking Afrin, a city that has maintained relative peace and stability throughout the Syrian civil war, in order to invest in the nationalist voter base and also pursue expansionist regional policies.
The UN should have prevented this occupation, which has the potential to destabilize the whole region, from the outset. While this is what should have happened, instead the UN Secretary General's Spokesperson Stephane Dujarric said "local administrators in Afrin are preventing civilians from leaving Afrin." I am sorry to say that statements like these only serve to encourage Erdogan. The people of Afrin do not want to leave their lands. Where else can the people of Afrin go? Afrin was actually a safe haven for over a hundred thousand people who had fled the war in neighbouring Al-Bab and Jarablus. Right now it is an area where people of all ages are dying from bombardments night and day. Footage of the FSA, who are fighting alongside the Turkish army in Afrin, mutilating a woman fighter's dead body is only one of many documents showing the brutality.
Dear Mr. Guterres,
I am a live witness to the massacre that occurred in the town of Cizre on 14 December 2015, on the 79th day of the blockade. I was there as an elected representative of my people. 280 people were massacred, from three-month-old babies, to eighty-year-old mothers. I was fired upon, and almost killed, while trying to take injured civilians to the hospital. Two weeks after this incident, the Turkish state and its state of the art equipped army burned 143 people alive in the basements of buildings in Cizre.
The United Nations High Commissioner for Human Rights, Zeid Ra'ad Al Hussein, had stated that what had occurred in both Sirnak's town of Cizre and Diyarbakir's town of Sur were "shocking". The subsequent report that was released by the United Nations High Commissioner for Human Rights had deemed what had happened as "chaos". The report stated that two thousand people had been killed, half a million people had been displaced, and that the towns were systematically destroyed. The report had also called upon the Turkish state to respect the fundamental rights of civilians.
Turkey did not respect both the European Court of Human Rights' judgment on protecting civilians and the UN's 'humanitarian plea'. The subsequent silence of the European Union and the United Nations had only served to encourage the Turkish state. With time, the Turkish government became more and more authoritarian. The UN's Special Rapporteur on Torture, Nils Melzer, said in a statement published last week that they were concerned by the rising cases of torture and malpractice in Turkey.
Dear Secretary General,
The Turkish President Erdogan has already turned into a war machine. Erdogan is proud of being the leader of a country where the people who ask for peace are punished, and the people who want war are rewarded. Everyday he announces civilians who are being massacred like a match score. The worrying statement by Turkish Prime Minister, Binali Yildirim, "we will place 350,000 Syrians into Afrin" is absolutely an indication of the planned ethnic cleansing based on demographic change in Afrin. The Turkish state's previous assaults in Jarablus, Azzaz and Mareh resulted in the Interior Ministry appointing governors and heads of security for these towns, effectively turning these areas into Turkish run territories.
The Turkish state, which has been encouraged by the fact that international institutions such as the UN have largely remained silent, continues its aggressive and invading stance now in Afrin. The Turkish state is denying killing civilians in Afrin. However, in wars the truth is lost first. The three-month-old Miray Ince who was killed in Cizre and three-month-old Diyana Xazî Salih who has been killed in a bombardment in Afrin are the victims of the same silence. If we look at what has happened so far, the Turkish state and FSA's progress towards Afrin may lead to a horrific massacre. If this is not avoided, the position of the UN, if it remains a mere on-watcher, will be questionable.
The UN, which was created after the destruction caused by the Second World War, must take a more active stance against this tragedy in the Middle East. The offensive initiated by Turkey against Afrin has the potential to ignite a new regional war. We invite the UN, as an organization responsible for pursuing global peace, to fulfill its mission by pressuring Turkey to end its occupation of Afrin."
https://anfenglish.com/rojava/open-letter-to-the-united-nations-on-turkey-s-afrin-operation-25372
By VOA [Public domain], via Wikimedia Commons
http://kurdishquestion.com/oldarticle.php?aid=cizre-is-like-kobane-and-sinjar-now-kq-exclusive-interview-with-faysal-sariyildiz-part-1
http://kurdishquestion.com/oldarticle.php?aid=resistance-is-life-silence-is-death-part-2-of-kq-s-exclusive-interview-with-faysal-sariyildiz
https://www.globalrights.info/?s=Cizre
AfrinAntónio GuterresFaysal SarıyıldızFree Syrian ArmyHDPKurdistanSyrian warTopUnited Nations
0 Uncategorised 4 years ago
The Constituent Council for The Federal System in Rojava/Northern Syria
We publish here the Statement issued by the Constituent Council for The Federal System in Rojava/Northern Syria
0 KURDISTAN 2 years ago
"Turkey seeks to open new lands for ISIS to prolong its life"
The General Command of the Military Councils in Al-Jazeera region called on human rights organizations, the European Union and the United Nations to take an anti-invasion stand
ROJAVA! …Political upheaval…military conflict…social revolution…
In the 2 years since the Turkish military declared war on the Kurdish people in the south east of their country (in Northern Kurdistan) there has been little concerted protest from the 'Left'
ARTICLES RECENT
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A Binding Treaty on Business and Human Rights
Brid Brennan and Gonzalo Berrón *	14th November 2021
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Kamel Jendoubi *	8th November 2021
GLOBAL RIGTHS
News & International Magazine
This site is considered a blog and not a newspaper on line. It does not pursue any commercial purposes and access is totally free. Some of the published images are taken from the Internet, as well as articles and news; if their use violates copyright, it communicates, and will be promptly removed. Of each article published in this site it is clearly indicated the source and the author. Not necessarily the www.globalrights.info site shares the contents and opinions that public and come from other sources and tested, with respect to which therefore declines all responsibility. The reader comments are not attributed to www.globalrights.info, but the readers themselves, which they fully accept responsibility
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Q: Inverting amplifier not acting as expected with non-ideal op amp I'm fairly new to using op amps, so this may be a simple issue. I am building an inverting amplifier for monitoring a negative voltage on an analog rail. Since the ADC I'm using requires a positive voltage an inverting amplifier seems to be the way to go.
First, here is the LTSpice model using the OP07 (I have tried a variety of op amps with little to no improvement)

In this configuration the output voltage is higher than expected. With a -2V input and unity gain I would expect the output to be 2V, however it is slightly higher at 2.097V. The voltage at the inverting pin is 48.9mV, which seems to be the cause of the higher than expected output voltage.
Things I've tried

*

*Changing V- to -5V. This solves the issue, but I'd prefer to not require another voltage rail

*Using an ideal op amp the circuit works as expected, further indicating there is some parameter of non-ideal op amps that I don't understand

Any suggestions are appreciated

A: OP07 input range is only guarranteed to within 2 V of the negative rail, typically 1 V. You need to use something like LM324 whose range includes the negative rail for it to work properly.
There are plenty of other opamps that will also include the negative rail. They tend to be called 'single supply' amplifiers, as they are intended to be used with ground as the negative rail. Most R2R (Rail to Rail) amplifiers will also handle inputs around 0 V properly.


They buy quality used sports and fitness equipment like baseball bats and softball gloves, lacrosse and golf gear, treadmills, ellipticals and more.
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We are located at 2963 Battleground Avenue in Greensboro, NC in Battleground Village shopping center.


Raja Felgata is a Dutch-Moroccan journalist from Amsterdam. After her journalism study she had dreams of working in broadcast media, because she didn't see cultural rolemodels in mainstream media. Her career started at the big local news broadcaster in Amsterdam: AT5. She became one of the first Moroccan news anchor in Holland and therefore paved the way for - and inspired many upcoming Moroccan journalists to be. Her enthusiasm and professional attitude were the reasons for national TV to make her an offer she could not refuse. She made her way onto national TV for the breakfast show called Good Morning Netherlands where she covered the news and produced items.
The past years she has been busy producing The Diversity Top 100. A magazine/platform which is based on the many 'Most powerful/influential lists made in Holland. These lists never represent the cultural diversity the country has, so she decided to make her own which proved to be a huge success. Representation in the media is her main objective.
Working on the 8th edition in 2018, the list is growing as a platform and as a movement with many partners from broadcast media, multinationals and government organizations. In 2011 she received a Democracy Ribbon for her work.
Her vision is to make hidden talents and influencers visible to the world and give them the platform they deserve to shine and to build a strong network that is as diverse as the diversity of the Dutch society. Raja has always fought for equality for women and is a strong outspoken personality. She also produces and hosts an online Q&A #LiveTalk – every Friday at 16hr, on Facebook which is a live video with quality discussions and interesting guests and topics.
She is the founder of Next Gen Women a new girls platform to connect leaders, and create an (inter)national platform for female leadership and inspiration.
She is part of the speakersteam of TedxMarrakech 2019.
Why does everyone hate modern architecture?


There are many things to think about when you're moving, such as finding a new home or adjusting to a new neighborhood. Finding a new Medicare Part D plan might be overlooked. Whether you're moving to a new state or a snowbird that migrates to a warmer climate during the colder months, it's important to know how relocating can affect your Medicare Part D coverage.


Questions & Answers / What's the difference between Hyaluronic acid and Collagen?
Question: How does an injectable filler of hyaluronic acid differ from collagen?
Answer: Our skin contains collagen protein fibers that are "swimming" in a Hyaluronic acid matrix normally. The older dermal fillers were collagen based. Some were animal collagen (cow or pig) and some were human collagen. They did not last very long and allergic reactions were common so testing was required with the animal collagens. Hyaluronic acid fillers like Restylane or Perlane or Juvederm are relatively newer and have a longer longevity and are now the main workhorse filler for most plastic surgeons and dermatologists.