AIMP : Events - PMA Meeting: What's The Value Of Music?
PMA Meeting: What's The Value Of Music?
With the explosion of social media & new media platforms, music is being used more than ever. How are copyrights being valued and compensated in this new world order? Join in a discussion with respected industry experts as we explore the intrinsic and monetary value of music.
Richard Bellis is an Emmy award-winning composer and author of "The Emerging Composer: An Introduction to the People, Problems and Psychology of the Film Music Business". He is a past president of the Society of Composers & Lyricists; served on the faculty of the University of Southern California: served on the Board of Governors for the Academy of Television Arts and Sciences and mentors the participants of the "ASCAP Television and Film Scoring Workshop with Richard Bellis". He currently serves on the Board of Directors of ASCAP.
Steve Celi has been at FOX for over 12 years. As Manager of Music for On-Air Promotion including TV, Radio and New Media, Celi oversees all aspects of music production, clearances and library music for all of the FOX primetime lineup including American Idol, X Factor, Glee, House, Bones, Fringe, New Girl, Terra Nova, So You Think You Can Dance, Hell's Kitchen, Master Chef, Kitchen Nightmares, Raising Hope, Cops, and the entire Sunday night lineup. Previously Celi worked for 5 years as head of music for E! Entertainment Television and is also a composer, producer, singer-songwriter, vocalist and father of 3.
Norman Chesky is the co-founder of Grammy Award winning audiophile record label, Chesky Records. Chesky Records has recorded hundreds of records with such legends as McCoy Tyner, Chuck Mangione, and the late Peggy Lee. He is also the co-founder of leading independent music library, Manhattan Production Music. His newest venture is HDtracks.com, a high-resolution digital music store featuring content from many heralded record labels. Chesky is a current Governor in the New York Chapter and two-time former Trustee in the Recording Academy. He is also a founding member of the PMA and currently sits on the board.
Steve Pecile is the President of Soundminer, Inc. and was a composer in a previous life writing for several children's series in Canada. Pecile also owned a post-production studio in Toronto, Canada where he, along with Justin Drury, began developing what would later become Soundminer. Now a world leader in audio software for professionals, Soundminer clients include both large and small post- production, production, broadcast, film, music and publishing companies. Advanced music searching software, advanced metadata management, web hosting and web portal software (with an advanced iPhone application option) as well as broadcast cue-sheeting software are just some of the notable array of products Soundminer offers.
David Renzer is a veteran music and entertainment executive whose career has included leadership positions with the world's largest and most well-known music publishing companies. With over 25 years of experience in music and entertainment, Renzer most recently served at the helm of Universal Music Publishing Group as Chairman & CEO, responsible for overseeing the activities of the company's 57 offices in 47 countries. Since Renzer joined the company (then called MCA Music Publishing) in 1996, UMPG grew exponentially through direct signings and catalogue acquisitions, including the BMG Music Publishing, Zomba, Polygram, and Rondor catalogues. Under Renzer's tenure, UMPG also became the global leader in the areas of Production Music, Christian, and Classical Music.
countries. Saba is a multi-instrumentalist, a Columbia grad and a founding father of the PMA.


Audi UK has promoted sales operations manager James Buxton to the role of head of fleet sales.
He replaces Tom Brennan, who left the carmaker towards the end of last year to pursue interests outside the VW Group.
Buxton brings 15 years' automotive sector experience, including two years each at Nissan Motor GB and Porsche Cars GB prior to his move to Audi in 2016 as national used car manager; a role which saw him drive significant growth in both used car volumes and network used car profitability.
More recently, Buxton's role as sales operations manager has seen him prove instrumental in rationalising the administration and performance of the various sales channels by forging stronger and more fruitful relationships, not only with the Audi franchise network but also with key stakeholders at parent company Audi AG and across the wider Volkswagen Group.


The Baton Rouge Police Department has a long history of nepotism and favoritism that predates the killing of Alton Sterling. However, recent events bring to light just how difficult the work of Mayor Sharon Weston Broome will be to reform the police department that she has inherited from former mayor Kip Holden. In recent weeks conversations around the pending DOJ decision in the Alton Sterling case have heated up, with expectations that the decision is fast approaching. With this in mind a recent promotion in the ranks of BRPD are potentially problematic.
The new head of uniform patrol from the police department is Capt. Duane Scrantz. He is the son of former Capt. Calvert Scrantz. The Scrantz family name in the Baton Rouge police department is one that has produced several of the leaders in the department. Randy, and Duane both sons of Capt. Scrantz, and Melissa Scrantz Salamoni the daughter of Capt. Scrantz, the wife of Capt. Noel Salamoni and the mother of Blane Salamoni the killer of Alton Sterling. That is right, in the top ranks of BRPD, Alton Sterling's killer has had his mother who is retired, his father who is the head of Special Operations, his uncle who is now the head of the largest division of the department uniform patrol, and his retired uncle and grandfather. So while we have been caught up on the last name Salamoni, it is really the Scrantz name that has long influenced the department.
Some would ask why should it matter? If they are good officers, so be it. The problem is, when you have Blane Salamoni, who killed Alton Sterling which caused national protest in a department where his father and uncle are in charge of giving officers orders after the DOJ decision comes down there is a huge conflict of interest. There are two scenarios here. The first is if, Blane Salamoni is charged in the death of Alton Sterling, his father and uncle are the shot callers in the police department for the response to what could be cheering from the streets of Baton Rouge. How does a father not see this as a insult? The second is, if the Salamoni isn't charged and protest against that decision erupt in the city, the two men over the largest divisions of response are relatives of the man the community feels should be held responsible for the death of Alton Sterling. There is no way these men can completely separate themselves from the relationship they have with their loved one. It would be foolish to expect that their response not be one of some sort of anger. Yet it was the decision of the police chief to promote Scrantz at a time like this to the head of uniform patrol. It is a most insensitive and irresponsible action by Chief Carl Dabadie.
The police union will come out and praise these men as first class officers, but that doesn't change the fact that these men are relatives of the killer of Alton Sterling and should not be in positions to call shots after this DOJ decision. Further it shows the fight that Mayor Broome has on her hands to reform the police department. There will be resentment within the ranks of leadership in this department because of the family ties that exist. Mayor Broome has said she will change the chief of police in the department, the question remains, how can change come when the ties run so deep in the department.
The next chief of police will have to fight against the ties that bind. The union that Capt. Calvert Scrantz helped to shape and some of the ranking officers he trained. These men and women are deeply connected, and if they uphold the actions seen in the video of Alton Sterling being killed, they indeed are a part of the problem. The problems in the BRPD, run deep, and must be cut out at the root in order to truly reform the department.
When the DOJ decision comes down, none of those related to Blane Salamoni should be allowed to make any decisions. They should all be placed on leave or desk duty until a understanding of the path forward is clear.


A day after Congress politician Sam Pitroda's statement demanding more 'facts and proof' on Balakot airstrike created an uproar, BJP national president Amit Shah, in a press conference in New Delhi Saturday, demanded an apology from Congress president Rahul Gandhi.
Shah questioned Congress' stand on Pulwama attack and asks if the grand old party believes that Pakistan has something to do with these terror incidents that keep happening on Indan soil. "Who is responsible for these attacks?" asked Shah.
Prime Minister Narendra Modi had Friday cited Pitroda's comments to launch an all out attack against the Congress on the issues of terrorism and national security.


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CVWD approves steep water bill hikes for small homeowners
Janet Wilson
The Coachella Valley Water District board voted Tuesday to approve a rate hike — the first of potentially several over the next five years — that includes steep increases for small homeowners beginning July 1.
"It's never a joy to increase rates... but I look across the (Coachella) valley and into Riverside and I think we're competitive," Director Peter Nelson said.
While a few customers objected by phone and Zoom before the vote, and 166 written protests against the increases were received, a whopping 64,906 written protests would have been needed to stop the vote per state law.
The proposed hikes each year are the maximum amounts that will be allowed. The board would need to publicly discuss and vote separately each year on an additional increase.
Director Anthony Bianco, the sole dissenter on the 4-1 vote, said while he ultimately decided to vote no, he understands that state law (known as Proposition 218) leaves the board with with no choice but to raise revenues in certain ways that aren't always favorable to the smaller user.
"We can't arbitrarily change things to make it more expensive for commercial and less expensive for homeowners," Bianco said. "Under state law we can't, our hands are tied."
Residents expressed frustration with how much the hikes would increase their bills, and also with the overall protest and comment process.
"Why on Earth are the brunt of expenses being put on individual homeowners rather than businesses that are making money?" asked one speaker who phoned in, identified only as Elizabeth.
She said the timing of the meeting early on a Tuesday during working hours, the fact that a tally of who had protested is not publicly available before the meeting, and other issues convinced her that "It did not seem like you really wanted to hear from me."
"I think the rate for domestic users is out of proportion to other users," said Bill Taylor said. "I mean if you're a huge user, your rates are actually going to be going down."
Jenny Bates of Salton City said, "The calculations of my bill show nearly a 25% increase, whereas the larger commercial rates are going to have a significant decrease. How can you justify that?"
Overall, the hikes if fully adopted would mean an average family that uses about 20 ccf per month could see their bill rise from $32 currently to $48 by 2026, according to agenda materials. A ccf, or one hundred cubic feet, equals is 748 gallons of water.
But some large user rates will actually fall starting this July 1, and some small, single-family users could see much higher initial rate increases.
The district said an independent study had found it needs to significantly increase its overall revenues each year through 2026 to cover expenses, including overhauling decades-old equipment. But by law, a spokeswoman said, the district can only allocate specific costs to the type of customer using them.
So while fixed costs will rise for everyone, other costs are apportioned based on how large a meter is being used by what type of customer. That means smaller homeowners who use less water could see rates go up sharply to cover their share of fixed costs, while larger users could see smaller hikes or even decreases. In addition, each type of customer pays for consumption costs.
"It's very complicated, I know," said spokeswoman Katie Evans. "This is not based on our choices or our discretion, this is by law."
For instance, according to examples laid out in the presentation, a single-family home in "Tier 1" that uses just a quarter of its allocated water could see its total bill rise from $11.84 to $16.41 a month when the new fiscal year begins in three weeks, or a 38.6% increase.
But an average home in "Tier 2" that uses slightly more than its allocated amount could actually see bills drop 79 cents each month, a reduction of 1.54%. A large, single-family home with a swimming pool in "Tier 4" that uses more than double its allocated water would see a July 1 rate increase of just 2.61% or $10.48 a month, according to the documents.
Large homeowner associations' outdoor landscaping rates could fall by as much a 16.51%, or about $223 in July if usage is cut sharply with efficiency measures, while HOAs that have leaking systems or otherwise regularly exceed their allowance could see rates climb $14.8% or about $3,614 in July.
Customers can go to cvwd.org/ratechanges to calculate how much their own bills might rise.
Because several older customers on fixed incomes and others submitted written comments saying they could not afford another rate increase, board members asked staff to publicly explain a rate relief program available to those truly in need, which allows up to $100 annually in subsidies.
"One hundred dollars is not a lot of money but for some of our customers that can mean six months of water," said director John Aguilar.
Board President John Powell said they might ask staff to consider raising the subsidy amount in the future.
How the money would be allocated
Customer rates will still be lower than other area water providers, according to the district, and much of the additional revenue would be used to pay for major updates and overhauls of aging pipes, reservoirs and other infrastructure.
This year's proposed budget also includes $2.4 million in salary increases, according to a staff presentation. The district has about 560 approved positions, and raises are based on merit and performance. Salaries are paid for by the fund that position serves, so if someone works only on a canal that typically serves large users, their salary is budgeted from the canal fund.
A chart that was part of the proposal for the rate hikes shows while CVWD customers currently pay less than Myoma Dunes, Coachella or Indio water customers, they could pay more than those districts by 2026, assuming those districts don't raise their rates, too. But CVWD rates could still be less than Beaumont Cherry Valley, Desert Water, Mission Springs or Eastern Municipal Water districts' customers.
CVWD serves approximately 110,000 customers over a sprawling area that covers approximately 1,000 square miles from the San Gorgonio Pass to the Salton Sea, mostly within the Coachella Valley in Riverside County. Its boundaries also extend into small portions of Imperial and San Diego counties. The district was founded in 1918, and some of its large pipes and other infrastructure are decades old.
The district last raised water rates two years ago, at a much lower rate than was recommended by staff.
Palm Desert resident Randall Roberts has sued CVWD five times over the the processes they use to set increases, but has yet to win in court, Evans said. He argues domestic water users like him have long unfairly subsidized large agricultural growers and other major users. CVWD has denied those charges and said it follows state law on its increases.
CVWD's board last week also approved rate increases for major growers, golf courses and other large pumpers who typically use their own well water but rely on CVWD equipment to pump and pipe it.
Janet Wilson is senior environment reporter for The Desert Sun. She can be reached at janet.wilson@desertsun.com or @janetwilson66 on Twitter

redpajama_set_name: RedPajamaCommonCrawl


Very many Belgian children were separated from their families, orphaned, killed and suffered from various types of physical abuse between 1914 and 1918 but they were not entitled to any special legal protection. Many of them suffered physically.
FACIAL INJURIES. Lucie V. was 13 when she was seriously injured by shrapnel in August 1918 in Koekelare (Dixmude). She was struck in the face and her entire chest. The Germans treated her and sent her to Saint-Jean hospital in Bruges to be operated on. She did survive but worked only from time to time after the war, as the lasting damage to her face was extremely debilitating.
BEATEN AT 3 YEARS OF AGE. Born in Brussels in 1911, William V. suffered severe injuries in his left leg. He was violently abused and beaten by the German soldiers for some unknown reason. He was offered care and treatment at Katwijk aan Zee in the Netherlands, along with other orphans. It was discovered during the medical examination that his entire left leg and foot were severely atrophied, resulting in 30% permanent atrophy.
LETHAL GASES. Two young teenagers suffered from poison gas in October-November 1918: Honoré D. in Ruddervoorde (Dixmude), and Marcel L. in Tournai.
Honoré, seeking refuge in the cellars of the Verscheure brewery, was affected by gas coming from the German lines, as the front was not so very far away. He was taken to Bruges where he was treated with a certain degree of success.
Unlike Marcel, who, unfortunately, did not survive the poisonous gases launched during a British bombing raid on the city of Tournai. He had sought refuge in a cellar with his family and their neighbours.
INJURED ON THE BEACH. 7-year-old Madeleine D. lived in Ostend. On the morning of 15 June 1915, a plane bombed the city before crashing into the sea, not far from the little girl. Madeleine was severely injured in the foot by shrapnel. She was taken to Saint-Jean hospital in Bruges, where she stayed for 4 months, being operated on several times.


"Being able to spend every day with a wonderful pack of dogs and giving them the opportunity to be their doggy selves - that is the highlight of my day!"
Dogs love being outside, sniffing around, and playing with their friends, and quite frankly so do we (well, maybe not the sniffing!). In fact, this love of dogs is what created the foundation for Hikin' Hounds, Dog Adventures. Dog walking is a social activity. It is meeting up with a good group of friends everyday and enjoying a fun-filled adventure together that deepens bonds and continually creates new memories. But even with all the fun there is a serious side to it too. Understanding how dogs interact, both with each other, their physical environment, and their human counterparts, is important in keeping our loved ones safe and healthy.
In 2006 Hikin' Hounds was born from a love of dogs and an outdoor lifestyle. Over the years Vancouver has grown into a vibrant city and with that has come a huge growth in the number of dogs at the local dog parks and beaches.
Cora Seppala is the owner and primary dog walker for Hikin' Hounds. Surrounded by animals her entire life and having a love for the outdoors, she decided to combine her two greatest passions into a career.
Our mission is simple, we want to help owners have rewarding relationships with their dogs by providing safe, reliable and fun dog walking services. We strongly believe in dogs being allowed to be dogs!
Our number one priority is the well being of our dogs. Cora is an avid dog lover with 5 years of professional dog walking experience. We are licensed in Vancouver and North Vancouver and are fully insured by Profur.


(July 6, 2013) Coming into the Wimbledon final, Mike and Bob Bryan had won 23 consecutive matches. The last time the twins saw defeat was April 21, 2013 when they failed to capitalize on seven match points against Nenad Zimonjic and Julien Benneteau in the Monte Carlo Masters final.
Less than 15 minutes into today's final, the Bryan's opponents, Ivan Dodig of Croatia and Marcelo Melo of Brazil, were playing like the team that hadn't lost a match in nearly three months. In Bob Bryan's first service game, the overwhelming underdogs quickly created two break points and converted the second after Dodig nailed a marvelous return at Bob's feet nd the 6'8 Brazilian put away the response with an overhead.
On their own serve, Dodig and Melo were serving huge facilitating many short points finished by simple volleys and overheads. In addition, Dodig and Melo were varying their formations and really did an effective job keeping the Bryan's guesing especially with the I-formation. For those not familiar, the I-formation is when the server's partner crouches down hovering over the center service line as the server moves near the center mark on the baseline. This formation is a difficult one to consistently execute but it keeps the returners guessing because they aren't sure where the net player and the server will move. Thus, if you have a team like the Bryan's who can drill cross court returns all day long, it helps to keep them honest and prevents them from entering a rhythm off the return.
Five games in and the Bryan's were in paramount danger of losing a 6-0 set for the first time since the 2012 Australian Open as they fell behind 5-0. Amazingly enough, the Bryan's have only ever lost five 6-0 sets during their professional career. The Bryan's were able to escape from a 0-5, 15-30 hole, break their opponents, and hold once more before dropping the first 6-3 in 31 minutes.
Looking back, the three games the Bryan's rallied off at the end of the first set were crucial. It was abundantly clear the Bryan's had gained a sizeable amount of momentum despite losing the set.
This transition in momentum translated into a fast start to the second set. The Bryan's broke serve after Dodig, who had been extremely potent on serve in the first set, gifted away the break with a double fault.
To make matters worse for Dodig and Melo, their cogency off the return completely vanished in the second set. Daren Cahill of ESPN astutely pointed out that the Bryan's began to introduce the body serve with increased regularity in the second stanza of the match. This tactic seemed to jam Dodig and Melo both physically and mentally. Not only were the Bryan's hitting more unreturnable serves, but they seemed to draw Dodig and Melo into a major state of confusion. The Brazilian and the Croatian, when given a chance to cleanly hit a return, continually kept going down the line at the net player. And almost every time they did this, the Bryan's made sure to make them pay for their mistake and end the point then and there. Such a bizarre strategy, whether decided upon or forced by the powerful serves of the Bryan's, is not bound to work considering how swift the Bryan's hands are at net.
All the Bryan's needed in the second set was one break, and behind 15/16 first serve points won, they closed out the set 6-3 without facing a break point.
As the third set commenced, one of the notes I wrote to myself was "Not seeing too many down the line returns from the Bryans." Ultimately, one of the main factors in the Bryan's success in the match was their ability to consistently strike dipping, cross-court returns. Dodig and Melo continually returning at the net player really made breaking serve nearly impossible.
In addition, on serve, Dodig and Melo seemed less willing to stray from standard formation as the Bryans started to dial in on their returns. The lack of formation variation extended to serve placement as Dodig and Melo hit almost all of their serves into the Bryan's backhand. Serving into the Bryan's backhand is definitely the smart play but if you do it over and over and over, it becomes far too predictable. The Bryan's broke to go up 2-1 and were cracking the backhand returns that failed them earlier in the match. Needless to say, the twins had Dodig and Melo right where they wanted them.
The patterns I previously described held suit for the rest of the third set. The only inroad Dodig and Melo made in a service game was when the Bryan's were serving at 3-2 30-30. Mike Bryan quickly eradicated any notions Dodig and Melo had of breaking nailing a body serve and then an ace to hold for 4-2.
Winning the third set 6-4, the result seemed inevitable. The fourth set was definitely duller than the other sets and was characterized by a series of quick holds. The Bryan's eventually broke through at 4-4 and put the match in the hands of Bob Bryan's reliable lefty serve. Bob hit a monstrous serve down the middle at 30-15 and ended the match just like Marion Bartoli did in the Women's Singles Final– with an ace.
The Bryan's celebrated the win with their trademark chest-bump. With the victory, the Bryan's became the first doubles team in the open-era to hold all four majors at the same time. With a win at the U.S. Open in September, the Bryan's would be the first team to complete the calendar year slam since Ken McGregor and Frank Sedgman did it 1951 and be only the second doubles team in tennis history to do so.
March 23, 2013 — It has been barely a year since John Isner defeated world No. 1 Novak Djokovic in the semifinals of Indian Wells to reach his first career final at a Masters 1000 tournament. While he could not claim the title there, Isner appeared to have notched a decisive breakthrough in his career that would propel the top-ranked American man forward.
Events since then have questioned this interpretation of that memorable fortnight in the desert, especially over the last few months. Struggling for form from the US Open onward, Isner absorbed a serious blow when a knee injury forced him to withdraw from the Australian Open. That injury, not unexpected for a player of his height, disrupted the rhythm of his preparations for the 2013 season and undermined his confidence. At the Memphis indoor tournament in February, he lost his opener in straight sets to Denis Istomin, a player who normally should not have troubled him. But his slump reached its nadir at Indian Wells, the scene of his greatest triumph to date. Returning to the California desert, Isner lost his first match to Lleyton Hewitt as virtually every component of his game abandoned him at critical moments. With that loss came the loss of his status as the top-ranked American man, now held by Sam Querrey.
A man who shines most on home soil, Isner desperately needed to avoid a similar exit at the outset of the Miami tournament. With the long European swing ahead, he could not afford to let his confidence sink any lower before the inevitable setbacks on the red clay that dulls his greatest weapons. The Sony Open thus loomed large in the trajectory of his season as his last chance to regroup before the US Open Series in July. Against the occasionally dangerous Croat Ivan Dodig, who has defeated Nadal on North American hard courts before, Isner needed all of his perseverance and first-strike power to survive.
While he dropped serve four times across the three sets, an uncharacteristic number for him, the towering man from the University of Georgia showed resilience in rallying from losing the first set and from the brink of defeat in the third. Breaking Isner at 5-5 in the final set, Dodig served for the match at a stage when the reeling competitor across the net might well have resigned himself to a third straight loss. Despite the sweltering heat and his inconsistent form, Isner persevered to strike some of his best returns and play some of his most opportunistic tennis in the twelfth game and in the tiebreak that followed. Taking a lead at the outset, he never trailed in the tiebreak as he approached the net aggressively behind his serves and stayed just consistent enough from the baseline to earn the crucial mini-break that he needed for a 4-6, 7-5, 7-6(5) victory.
Finishing the match with a thunderous first serve out wide, Isner showed just how much the victory meant to him by leaping in the air on his way to the net for the handshake. Even in view of the match's airtight scoreline, that reaction might have surprised some onlookers because of his favored status and the early-round setting. But the context in which this victory came provided ample explanation for Isner's delight in eking out the type of nail-biting epic that he has played so often in his career. These are the matches that can restore a player's confidence in his ability to deliver at key moments, so the tenuous nature of his triumph in fact might have boosted him more than a routine win would have.
Always a perfectionist who demands a lot from himself, Isner expressed disappointment about losing his serve so often on a day when he otherwise had strong serving statistics. But he found it "a positive that I lost my serve four times and was still able to win the match." Isner also acknowledged that he "needed [the win] for sure" because of a difficult season in which he had "lost matches I feel like I could have won," always a demoralizing feeling for a tennis player.


Athletes turn out to be nervous throughout competition, it is a natural pat of the training curve. Baseball Almanac has MORE than 500,000 pages of baseball history, MORE than 1,500,000 quick information, unique research from acknowledged specialists AND material not found or seen on some other web site on this planet. I remember when Derrick Thomas, the linebacker for the Kansas City Chiefs, died tragically, and in one column I called for him to be immediately enshrined in the Pro Football Hall of Fame.
Time for the best to face off in quest of a hoop and Wheaties field, and time for the Baseball Project to announce that they are within the ultimate phases of including yet one more compelling batch of timeless (or not less than 'timely') songs to their sporty cannon. Instant replay has been round for a long time now and I was not at all shocked after I heard that it was going to be used in soccer and it was only a matter of time earlier than baseball jumped in and adopted the same system. Millions of fans world wide may now watch the games stay and cheer their favorite heroes.
But The Baseball Project has since blossomed into a full-fledged, much-beloved band in its own right, one which at present includes drummer Linda Pitmon (Steve Wynn and the Miracle three, Zuzu's Petals) and R.E.M.'s Peter Buck and Mike Mills on its official roster, and one whose following and creativity has steadily grown with every release and tour.
One turn at bat for every group constitutes an inning; 9 innings make up a baseball recreation. The quantity of women in baseball was about to extend because the Second World War saw many men go off to battle for his or her country. The eight players involved get suspended, and later are banned from baseball for life. Haupert's The Economic History of Major League Baseball reports that common salaries went from $45,000 in 1975 to $289,000 in 1983 and to $1.2 million in 2002. Later, and to add some variety to this fascinating matter, one of many many baseball scandals embrace the 1919 Chicago White Sox sellout.
Formed in 2007 by Scott McCaughey (Young Fresh Fellows, The Minus 5, R.E.M.) and Steve Wynn (The Dream Syndicate, Steve Wynn and the Miracle 3, Gutterball), The Baseball Project began as a method for a couple of followers to pay musical tribute to our national pastime — and maybe rating some free baseball tickets in the course of. The reserve clause, part of all organized baseball contracts, forbade ballplayers to depart the group with which they'd signed with out that team's approval even after the term of the contract ended. The website has rapidly grown into an interactive baseball encyclopedia filled with practically 500,000 pages of in-depth baseball details, authentic baseball research and baseball statistics not discovered anyplace on the Internet.


Donna Bianco is married to a talented general contractor and mother to an amazing son who is in webdesign. Her underground house designed by her husband has been on television's HGTV. She has a masters degree in Special Education and 30 years experience in teaching both in NY and NC. She also started her own private school in 2006 along with a pizzeria which quickly grew into a thriving business.
In 2012 Bella Donna purchased the property at the old Pizza Hut location in downtown Pittsboro. With this, Donna was able to create "Bella Donna Italian Restaurant". She loves cooking REAL food for her customers and is very careful about every item on the menu being clean and from a reliable source. She purchases a cow every 6 months from a local farmer as well as other local fare and has gardens in downtown Pittsboro, at her home and connects with local farmers.
She loves cooking for people, mangia, mangia, (eat,eat) is in her DNA.


Description Text on front states: Xtreme Entertainment, Inc. and PHD Entertainment, Inc. proudly presents SBGA Summit, The State of Black Gay America Summit.
Citation Q110_textiles073, Lorraine Fontana papers, Archives for Research on Women and Gender. Special Collections and Archives, Georgia State University.


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Dr. Janet Hartley leads international Decision Sciences Institute
Dr. Janet Hartley, a professor of management at Bowling Green State University, has begun her term as president of the Decision Sciences Institute (DSI). She was elected last year to lead the professional organization of more than 2,200 academicians and practitioners worldwide.
In November, the institute will return to New Orleans, the site of its first conference in 1969, for its annual conference and celebration of its 50th anniversary. Hartley is an active, longtime DSI member, having joined the institute in 1993 as a doctoral student. Over the years, she has served in various roles on DSI committees, conference planning teams and on the DSI Board of Directors.
The first person from BGSU and the first from a Mid-American Conference school to lead the organization, Hartley joins an elite group of past presidents from prestigious universities such as the University of Notre Dame, Michigan State University, Ohio State University, Stanford University and the University of North Carolina-Chapel Hill.
"We are proud to have Jan serving as the new president of DSI," said Ray Braun, dean of the College of Business. "DSI is held in such high regard globally, and we are fortunate to have her latest leadership role bring increased visibility to our supply chain management program at BGSU. It also says a lot about the high regard that Jan's colleagues around the world have for her."
DSI is concerned with the application of quantitative and behavioral methods to the problems of society, with the goal of improving managerial decisions. The institute provides an international forum for presenting and sharing research in the study of decision processes across disciplines through its national, international and regional conferences, competitions and publications, which include the academic journals Decision Sciences and Decision Sciences Journal of Innovative Education and the newsletter Decision Line. Among DSI's purposes is improving educational programs and instruction in the decision sciences. It also offers professional development activities and job placement services.
A specialist in supply chain management in the BGSU College of Business, Hartley has taught at the University since 1994. She served as chair of the Department of Management from 2002-10 and as director of BGSU's Supply Chain Management Institute from 1999-2003 and again from 2010-17.
She has published 37 refereed academic journal articles and three books. Her research has been published in the Journal of Operations Management, Journal of Supply Chain Management and the Journal of Business Research. She also serves as an associate editor for six academic journals, including the highly regarded Journal of Operations Management. The International Journal of Operations and Production Management, a top tier journal, will present her the 2019 Best Associate Editor Award at the 26th annual EurOMA Conference.
Hartley is also highly regarded for her contributions to teaching excellence. She received the international APICS (now the Association for Supply Chain Management) Student Chapter Mentor Award twice, in 2014 and 2017, an honor presented to only one person a year. In 2017, an article co-authored with BGSU colleague Dr. Karen Eboch and BGSU alumnus Jonathan Gilberg received the Best Teaching Brief Award from the Decision Sciences Journal of Innovative Education. This work also received the Decision Sciences Instructional Innovation Award in 2015.
In her introductory letter to the DSI membership as president, Hartley called for the organization to continue its focus this year on its strategic goals of growing and retaining members, increasing the stature of DSI academic journals and building new and enhancing existing connections with DSI stakeholders. Further, she is working to expand the number of international chapters and is focusing on ways to increase collaboration between DSI and other academic and practitioner organizations.


MARY BERNARD (Verena Bütler) was born in Auw, in the Canton of Argovia, in Switzerland, on the 28th of May 1848 and was baptised on the same day. She was the fourth child of Henry and Catherine Bütler, modest but exemplary country people, who educated the eight children born of their marriage in the love of God and of neighbour.
Gifted with excellent health, Verena grew up happy, intelligent, generous and a lover of nature. She began to attend school at seven years of age. The fervour and commitment with which she made her First Communion, on the 16th of April 1860, remained constant in her for the rest of her life.
Devotion to the Eucharist would, in fact, form the foundation of her spirituality.
Having completed her elementary studies at the age of 14, Verena dedicated herself to farm work and experienced affection for a worthy young man with whom she fell in love. On feeling the call of God, she broke off the engagement in order to turn completely to the Lord. During this period in her life she was granted the grace of enjoying the presence of God, feeling Him very close. She herself said: "To explain this state of soul to someone who has never experienced anything similar is extremely difficult, if not impossible".
And again: "The Holy Spirit taught me to adore, praise, bless and give thanks to Jesus in the tabernacle at all times, even at work and in real life.
Drawn by the love of God, she entered a convent in her region as a postulant at 18 years of age. However, becoming aware that it was not the place to which the Lord was calling her, Verena very quickly returned home.
Work, prayer and apostolic activity in the parish kept her desire for the consecrated life alive. At the suggestion of her Pastor, Verena entered the franciscan Monastery of Mary Help of Sinners in Altstätten on the 12th of November 1867. She took the franciscan habit on the 4th of May 1868, taking the name of Sister Mary Bernard of the Heart of Mary, and made her Religious Profession on the 4th of October 1869 with the firm proposal of serving the Lord until death in the contemplative life.
She was very soon elected Mistress of Novices and Superior of the Community on three occasions, carrying out this fraternal service for nine consecutive years. Her zeal and love for the Kingdom of God had prepared her to begin a new missionary experience. Having willingly accepted the invitation of Msgr. Peter Schumacher, Bishop of Portoviejo in Ecuador, who, outlining the precarious situation of his people, asked her to come to his Diocese. Mary Bernard clearly saw the will of God, who was calling her to be an announcer of the Gospel in that far away country, in this invitation.
Having overcome the initial resistance of the Bishop of St. Gall and obtained a regular pontifical indult, Sr. Mary Bernard and six companions left the Monastery in Altstätten and set out for Ecuador on the 19th of June 1888. Only their light of faith and zeal to announce the Gospel sustained the Blessed and her companions in the difficult separation from their beloved Monastery and Sisters. In her intentions, Mary Bernard thought of giving birth to a missionary foundation dependent on the Swiss Monastery.
The Lord, however, made her instead the foundress of a new Religious Congregation, that of the Franciscan Missionary Sisters of Mary Help of Sinners.
They were received paternally by the Bishop, who entrusted to Mary Bernard the community of Chone, which presented a distressing spectacle because of the total lack of priests, scant religious practice and rampant immorality. Mary Bernard became "everything to everyone", placing prayer, poverty, fidelity to the Church and the constant exercise of the works of mercy at the base of her missionary work. She, together with her daughters, began an intense apostolate among families, deepening their knowledge of the language and of the culture of the people. The first fruits did not delay in maturing. The Christian life of the people blossomed again as if by magic.
The new Franciscan Congregation also grew in number and two filial houses were founded in Sant Ana and Canoa. Very soon after however, the missionary work of Mother Mary Bernard was marked by the mystery of the Cross. Many indeed were the sufferings to which she and her daughters were submitted: absolute poverty, torrid heat, uncertainty and difficulties of every kind, risks to their health and security of their lives, misunderstanding on the part of ecclesiastical authorities and, besides, the separation of some Sisters from the community, establishing themselves later as an autonomous congregation (the Franciscans of the Immaculate: Blessed Charity Brader). Mary Bernard underwent all this with heroic fortitude and in silence without defending herself or nourishing resentment towards anyone, but forgiving them from her heart and praying for those who made her suffer.
As if all these trials were not enough, a violent persecution in 1895, begun by forces hostile to the Church, obliged Sr. Mary Bernard and her Sisters to flee from Ecuador. Without knowing where to go, she went, with 14 Sisters, towards Bahia, from where she continued towards Colombia.
The group was still wandering when it received an invitation from Msgr. Eugene Biffi to work in his Diocese of Cartagena. So, on the 2nd of August 1895, the feast of the Porziuncola of Assisi, the Foundress and her Sisters, exiled from Ecuador, reached Cartagena, and were received paternally by the Bishop. They found hospitality in a female hospital, commonly called a "Pious Work". The Lord had led her by the hand towards that asylum, where Mother Mary Bernard would remain to the end of her life. After the house in Cartagena, the Foundation was extended not only in Columbia but also in Austria and Brasil.
With a compassionate heart, authentically franciscan, she engaged above all in relieving the spiritual and material needs of the poor, whom she always considered to be her favourites. She used to say to the Sisters: "Open your houses to help the poor and marginalised. Give preference to the care of the indigent over all other activity". The Mother guided her Congregation over thirty years. Even after resigning from the Office of Superior General, she continued to animate her dear Sisters with feelings of true humility, especially through the example of her life and her words and writings.
Struck by piercing hypo-gastric pains, while at the "Pious Work" in Cartagena, an establishment of her Daughters, and loved and venerated by all as an authentic saint, Mary Bernard quietly went to sleep in the Lord on the 19th of May 1924. She was 74 years of age, 56 in the consecrated life and 38 in missionary life. News of her death spread quickly. The Pastor of the Cathedral of Cartagena announced her passing away, saying to the faithful: "A saint has died in this city, this morning: the reverend Mother Bernard!". Her tomb immediately became a centre of pilgrimage and a place of prayer.
The apostolic zeal and ardour of charity of Mother Mary Bernard are being re-lived today in the Church, particularly through the Congregation founded by her, present at the moment in various countries on three continents. The Blessed can be pointed out as an authentic model of "inculturation", the urgency of which the Church has underlined for an efficient announcement of the Gospel (cf. Redemptoris Missio, n. 52). She incarnated perfectly her orienting motto: "My guide, my star, is the Gospel".
During her life, she found support and comfort in God alone.
From the time she abandoned her homeland, to which she never went back, when she left her dear Monastery in Altstätten and during her untiring apostolic activity, she was always sustained by a solid spirituality of unceasing prayer, heroic charity towards God and her neighbour, by a faith that was solid as rock, by an unlimited trust in the Providence of God, by evangelical strength and humility, and by a radical fidelity to the commitments of her consecrated life. From her contemplation of the mysteries of the Most Holy Trinity, the Eucharist and the Passion of the Lord, she also drew the gift of mercy towards all, which she practised and left as the particular charism of her Congregation. Very devoted to the Virgin Mother of the Lord, she wished her Congregation to have Our Lady Help of Sinners as mother, protector and life model in her discipleship of Christ and in her missionary activity. As a Franciscan, she cultivated the same veneration which St. Francis of Assisi nourished for "Holy Mother Church", Pastors and priests, whom she called "the anointed of the Lord".
The Blessed left an admirable example of the biblical woman: strong, prudent, mystical, spiritual teacher and notable missionary. She left the Church a wonderful testimony of dedication to the cause of the Gospel, teaching all, especially today, that it is possible to unite contemplation and action, life with God and service to humanity, bringing God to men and women, and men and women to God.
The Servant of God Pope John Paul II conferred the title and honour of Blessed her on the 29th of October 1995. The Holy Father, Benedict XVI, inscribed her in the register of Saints on the 12th of October 2008.


The vertebrate neural retina is derived from the ventral region of the forebrain. In this region, six classes of neurons differentiate and form the neural circuit underlying visual transduction. Thus, the retina provides an excellent model for studying cell differentiation and neural circuit formation in the vertebrate brain. Furthermore, more than one hundred hereditary retinal diseases causing photoreceptor degeneration have been identified in humans. Understanding the pathological processes of photoreceptor degeneration is an important issue from a medical perspective. We are currently investigating the mechanisms underlying retinal cell differentiation and photoreceptor degeneration, using zebrafish as an animal model. The results have revealed that five signaling molecules, including Histone deacetylase 1 (Hdac1), regulate retinal neurogenesis in zebrafish. Regulatory factors that modulate the Hdac1 activity during retinal neurogenesis have been examined. Furthermore, to examine cell-cycle regulation in retinal neurogenesis with high accuracy, we visualized cell-cycle phases differentially with fluorescent proteins using zebrafish fluorescent ubiquitination-based cell cycle indicator (Fucci). We applied this Fucci technique to zebrafish lens epithelium and revealed a spatial regulation of cell proliferation and migration. In the project on photoreceptor degeneration, we have identified zebrafish mutants showing photoreceptor degeneration. In 2012, we revealed that a zebrafish b-SNAP mutation causes photoreceptor apoptosis, which depends on a BH3-only SNARE, BNip1. Because b-SNAP regulates the fusion of transport vesicles to intracellular membrane organelles, this finding suggests that BNip1 mediates photoreceptor apoptosis in response to vesicular fusion defects.
The vertebrate retina is initially specified in the anterior neural plate and evaginates from the ventral region of the forebrain as the optic cup. In this region, six major classes of retinal neurons and one class of glial cells differentiate to form the neural circuit that mediates phototransduction and visual processing (Fig. 1). Thus, the retina provides an excellent model for studying the mechanisms underlying cell differentiation and neural circuit formation in the developing brain. In the developing zebrafish retina, neurogenesis is initiated at a few cells adjacent to the optic stalk and progresses to the entire neural retina. This pattern of retinal neurogenesis provides a good model for studying the mechanisms regulating the spatial and the temporal pattern of neurogenesis in the nervous system. Previous studies, including research in our lab, suggest that at least five families of signaling molecules regulate the pattern of retinal neurogenesis in zebrafish (Fig. 2). Fibroblast growth factors (Fgfs) are expressed in the optic stalk and are required for the initial induction of retinal neurogenesis in zebrafish. The Hedgehog (Hh) signaling pathway is important for the progression of retinal neurogenesis in zebrafish. Activation of the Wnt signaling pathway promotes cell proliferation in the zebrafish retina, and activation of the Notch pathway inhibits retinal neurogenesis. Previously, we identified a zebrafish histone deacetylase 1 (hadc1) mutant, in which retinal progenitor cells fail to exit from the cell cycle and continue to proliferate. HDAC1 promotes retinal neurogenesis by suppressing both the Wnt and Notch signaling pathways. HDAC1 is recruited to several transcription repressor and corepressor complexes as well as those in the Wnt and Notch pathways. To elucidate the HDAC1-dependent regulation of retinal neurogenesis, we have identified a new mutation, oki150, that modifies the neurogenic defects in heterozygous hdac1 mutants. In 2011, using polymorphic markers, we mapped the oki150 mutational locus on zebrafish chromosome 20. We currently clone the oki150 mutation.
Figure 1: Zebrafish retina. Plastic section of 3 dpf zebrafish retina. Six major classes of retinal neuron including photoreceptors differentiate and form layered structures.
Figure 2: Molecular signaling network regulating retinal neurogenesis in zebrafish. FGF and Hh regulate the induction and progression of retinal neurogenesis in zebrafish. Wnt and Notch signaling pathways promote cell differentiation and neurogenic inhibition, respectively. Hdac1 promotes retinal neurogenesis by suppressing both Wnt and Notch signaling pathways. A novel mutation namely oki150 interacts with Hdac1 to promote neurogenesis.
The first step of neurogenesis is the exit from the cell cycle. Previously we showed that the earliest neurogenic marker, ath5 (also designated as atoh7), is initiated in the G2 phase in retinal progenitor cells just prior to the final cell division, which generates two neuronal daughter cells. Thus, it is very likely that the commitment to the retinal neuron is associated with cell-cycle progression. To accurately understand the relationship between cell proliferation and cell differentiation, we visualized cell-cycle phases differentially with fluorescent proteins, using the zebrafish Fucci (fluorescent ubiquitination-based cell cycle indicator) (Sugiyama et al., 2009, Proc Natl Acad Sci USA 106, 20812–20817). In the Fucci system, the cell-cycle dependent expression of two cell-cycle regulators, Geminin and Cdt1, are visualized with fluorescent proteins fused to their regulatory peptide sequences. We generated the zebrafish transgenic line carrying genes encoding mCherry-tagged Geminin and green fluorescent protein (GFP)-tagged Histone 2A. In this transgenic fish, we were able to clearly distinguish three different phases in the developing retina as well as the lens; the G1, S-G2, and M phases (Fig. 3A). Furthermore, we were able to observe chromosome condensation in the M phase (Fig. 3B) and measure the orientation of cell division from in vivo time-lapse imaging data.
In 2012, using this transgenic fish, we observed the cell-cycle progression, cell division, and cell migration in the zebrafish lens epithelium using time-lapse techniques, because the lens epithelium is more easily accessed than the neural retina (Fig. 4A). We found that cell proliferation was highly active in a marginal zone just anterior to the equator in the lens epithelium. Furthermore, cell-division orientation was biased along the circumferential axis in this proliferating zone (Fig. 4B). These data suggest that cell proliferation and cell division are dynamically regulated in the zebrafish lens epithelium. In many developing tissues, it has been reported that cells tend to divide along their longest axis. This is referred to as "the Hertwig rule". We found that the longest axis was also circumferentially biased in the proliferating zone in the zebrafish lens epithelium (Fig. 4C), suggesting that lens epithelial cells follow the Hertwig rule. These observations suggest that apical cell geometry correlates with cell division orientation in the proliferating zone of the lens epithelium. Since cell geometry depends on cell adhesion and a cell adhesion molecule, E-cadherin, is expressed in the lens epithelium, we are examining epithelial cell behaviors in zebrafish E-cadherin mutant.
Figure 4: Cell proliferation and division are spatially regulated in the zebrafish lens. (A) Schematic drawing of lens structures. Anterior lens epithelial cells (yellow) are proliferative and start to differentiate into lens fiber cells (green) at the equator (orange). Differentiating lens fiber cells elongate to cover the old lens fiber core (blue). (B) (Left) Plotting of mitosis position on anterior projection view of lens epithelium. Cell division was more frequent in the marginal zone anterior to the equator. Angles of cell-division orientation relative to the circumferential axis are indicated with color tone spectrum from red (0 degree) to blue (90 degree). Cell division was the most frequent in the marginal zone anterior to the equator and its orientation was biased circumferentially. (Right) Profile for cell division orientation. (C) (Left) Labeling of lens epithelium at the proliferating zone with a fluorescent lipid dye (green), which visualizes cell membranes. (Right) Histogram of angle of cell division to the circumferential axis. A majority of cell divisions are in parallel with the circumferential axis in the peripheral region.
Visual information processed in the retina is transmitted from retinal ganglion cells to the second visual center, called the optic tectum, through retinal axons. In lower vertebrates including fish, all retinal axons project to the contra-lateral side of optic tectum and no ipsi-lateral projection occurs, resulting in the formation of the optic chiasm, where retinal axons from the left and right eyes cross without combining. Our previous study showed that retinal axons are misrouted to the ipsi-lateral side of the optic in zebrafish N-cadherin mutants, suggesting a role of cell adhesion in retinal axon guidance at the midline. However, the mechanism underlying retinal axon guidance in crossing on the midline remains to be elucidated.
The molecular mechanism underlying axon guidance at the midline has been studied using commissural neurons in the vertebrate hindbrain and spinal cord as well as in the Drosophila embryonic central nervous system (CNS). It is generally accepted that pre-crossing axons are attracted by a guidance cue emanating from the midline tissue, Netrin, and that the midline tissue expresses not only Netrin but also a repellent cue, Slit. A recent model proposes that pre-crossing axons are insensitive to Slit and only respond to Netrin, resulting in the attraction of their growth cone to the midline. When their growth cone passes over the midline, the sensitivity to Slit is increased, which enables post-crossing axons to leave from the midline. It has been reported that the expression level of a receptor of Slit, namely Roundabout (Robo), is very low in pre-crossing axons but increased in post-crossing axons in Drosophila CNS. In addition, it was reported that one of the Robo family proteins, Robo3, is exclusively expressed in the pre-crossing axons and functions as dominant-negative repressor of Robo1, which is thought to mediate repulsive response instructed by Slit. However, the way in which the responsiveness of Slit is differentially regulated in pre- and post-crossing axons remains unclear.
We have established an in vitro culture assay system using commissural axons that reflects the acquisition of Slit responsiveness in post-crossing axons. Using this assay system, we showed that a Robo1-associating deubiquitinase, USP33, is required for the acquisition of Slit responsiveness and crossing of commissural axons over the midline. From 2011 to 2012, we revealed that the endocytic trafficking of Robo1 modulates its own expression level on axons as well as the sensitivity of axons to Slit. These findings suggest a new mechanism that modulates axonal responsiveness to guidance cues in crossing the midline of the CNS. We are confirming the role of the endocytic trafficking in axon crossing the midline in vivo using mouse and chick neural tube.
Photoreceptors are highly specialized neurons that efficiently detect light stimuli. To date, more than a hundred genes associated with inherited photoreceptor degeneration have been identified in humans (see the homepage of the Retinal Information Network at http://www.sph.uth.tmc.edu/Retnet/). However, the mechanisms underlying the pathological processes involved in photoreceptor degeneration also remain to be elucidated. To determine the mechanisms underlying photoreceptor degeneration, we have screened zebrafish mutants with dysfunctional visual behavior by testing the optokinetic response. We identified several zebrafish mutants, in which photoreceptors differentiate but later degenerate. In 2010, we reported that one of these mutants carried a genetic mutation in cGMP-phosphodiesterase 6c (PDE6c), a mediator molecule of cone-specific phototransduction, suggesting a link between achromatopsia and progressive cone dystrophy. In 2012, we examined another mutant, coa, whose photoreceptors rapidly undergo apoptosis before maturation (Fig. 5A). We found that the coa mutant gene encodes b-soluble N-ethylmaleimide-sensitive factor attachment protein (b-SNAP) (Fig. 5B). b-SNAP regulates the fusion of transport vesicles to intracellular membrane organelles. These observations suggest that vesicular transport defects cause photoreceptor apoptosis in zebrafish.
Mitochondria-dependent apoptosis is promoted by proapoptotic Bcl2 family proteins, Bax, and inhibited by anti-apoptotic Bcl2 family proteins, Bcl2. BH3-only proteins promote apoptosis by modulating the balance between pro-apoptotic and anti-apoptotic Bcl2 proteins. We searched which BH3-only proteins are involved in the coa-mediated photoreceptor apoptosis and found that a BH3-only SNARE, BNip1, mediates the coa-mediated photoreceptor apoptosis (Fig. 5C). BNip1 is a component of the syntaxin 18 SNARE complex, and the syntaxin 18 SNARE complex regulates retrograde transport from the Golgi apparatus to the ER. b-SNAP promotes the recycle of vesicular fusion machinery, SNARE, by disassembling the cis-SNARE complex generated by vesicular fusion. Thus, it is likely that the syntaxin 18 cis-SNARE complex is accumulated in the coa mutant. We found that failed disassembly of the syntaxin 18 cis-SNARE complex activates the BNip1-dependent photoreceptor apoptosis in the coa mutant. These data suggest that the sytaxin 18 cis-SNARE complex monitors vesicular fusion competence and that BNip1 transforms vesicular fusion defects into apoptosis (Fig. 5D). Our findings indicate a novel role for BNip1in linking vesicular fusion competence and photoreceptor apoptosis.
Figure 5: BNip1 mediates photoreceptor apoptosis in response to vesicular fusion defects. (A) Zpr1 antibody labeling of 6 dpf wild-type and coa mutant retinas. All nuclei are counterstained with Sytox-Green (green). Arrowheads indicate zpr1 expression (magenta) in the CMZ of the coa mutant. (B) A non-sense mutation occurs at 152Y in b-SNAP gene in the coa mutant. (C) (upper panels) TUNEL (green) of 84 hpf wild-type and coa mutant retinas, and coa mutant retinas injected with a mixture of BNip1a and BNip1b morpholino anti-sense oligos. Arrowheads indicate apoptosis in the ONL. (lower panels) Zpr1 labeling (green) and GFP-tagged Peripherin (magenta) in 84 hpf wild-type, and coa mutant retinas, and coa mutant retinas injected with a mixture of BNip1a and BNip1b morpholino anti-sense oligos. Arrowheads indicate rescued photoreceptors. (D) BNip1 is a component of the syntaxin18 SNARE complex, which regulates retrograde transport from Golgi to ER. Vesicular fusion generates the cis-SNARE complex, which is subsequently disassembled by SNAP and NSF for SNARE recycle. In the coa mutant, b-SNAP activity is reduced, resulting in the accumulation of the syntaxin 18 cis-SNARE complex, which activates BNip1 pro-apoptotic activity. We propose that the syntaxin18 cis-SNARE complex functions as an alarm that monitors vesicular fusion competence and that BNip1 transforms vesicular fusion defects into photoreceptor apoptosis. Scale bars: 50 micro-m.
Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T. and Masai, I. (2013). The BH3-only SNARE BNip1 mediates photoreceptor apoptosis in response to vesicular fusion defects. Dev. Cell 25, 374 – 387.
Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T. and Masai, I. Genetic mutation of beta-SNAP causes photoreceptor degeneration through the activation of the BH3-only SNARE, BNip1. 10th International Conference Zebrafish Development and Genetics, Madison, USA, 20–24 June 2012.
Mochizuki, T., Suzuki, S., Sakaue-Sawano, A., Miyawaki, A. and Masai, I. E-cadherin controls apical cell geometry and orientation of cell division in the zebrafish lens epithelium. 10th International Conference Zebrafish Development and Genetics, Madison, USA, 20–24 June 2012.
Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T. and Masai, I. Genetic mutation of beta-SNAP causes photoreceptor degeneration through the activation of the BH3-only SNARE, BNip1. APDBC Taiwan 2012 Asia-Pacific Developmental Biology Conference 2012, Taipei Innovation City Convention Center, Taipei, Taiwan, 5–8 October 2012.
Mochizuki, T., Suzuki, S., Sakaue-Sawano, A., Miyawaki, A. and Masai, I. E-cadherin controls apical cell geometry and orientation of cell division in the zebrafish lens epithelium. APDBC Taiwan 2012 Asia-Pacific Developmental Biology Conference 2012, Taipei Innovation City Convention Center, Taipei, Taiwan, 5–8 October 2012.
Mochizuki, T. and Masai, I. Spatial regulation of cell proliferation and differentiation in the zebrafish lens. The 46th Annual Meeting of the Japanese Society of Developmental Biologists Matsue, Shimane, Japan. 28–31 May 2013.
Masai, I. Mechanism underlying lens differentiation through the ubiquitin-proteasome system. The joint meeting of the 27th annual meeting of the Japanese society of cataract and refractive surgery and the 51st annual meeting of the Japanese society of cataract research. Tokyo, Japan. 15–17 June 2012.
Masai, I. Mechanism underlying lens differentiation using zebrafish mutants. Wakayama Medical University, 15 June 2012.
Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T. and Masai, I. The BH3-only SNARE of syntaxin18, BNip1, is a mediator of photoreceptor apoptosis in response to vesicular fusion defects. The 35th annual meeting of the Molecular Biology Society of Japan. Fukuoka, Japan. 11–14 December 2012.
Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T. and Masai, I. Genetic mutation of beta-SNAP causes photoreceptor degeneration through the activation of the BH3-only SNARE, BNip1.The 18th Japanese Medaka and zebrafish meeting. Kyoto, Japan, 22–23 September 2012.
Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T. and Masai, I. The BH3-only SNARE of syntaxin18, BNip1, is a mediator of photoreceptor apoptosis in response to vesicular fusion defects. Neuroscience 2012. The 35th annual meeting of the Japan Neuroscience Society. Nagoya, Japan. 18–21 September 2012.
Nishiwaki, Y., Yoshizawa, A., Kojima, Y., Oguri, E., Nakamura, S., Suzuki, S., Yuasa-Kawada, J., Kinoshita-Kawada, M., Mochizuki, T. and Masai, I. Genetic mutation of beta-SNAP causes photoreceptor degeneration through the activation of the BH3-only SNARE, BNip1. Joint meeting of the 45th annual meeting of the Japanese society of Developmental Biologists and the 64th annual meeting of the Japanese society of Cell Biology. Kobe, Japan, 28–31 May 2012.
Mochizuki, T., Suzuki, S., Sakaue-Sawano, A., Miyawaki, A. and Masai, I. Profile of cell cycle, cell division, and cell shape in lens: possible determinants of lens morphology. Joint meeting of the 45th annual meeting of the Japanese society of Developmental Biologists and the 64th annual meeting of the Japanese society of Cell Biology. Kobe, Japan, 28–31 May 2012.
Mochizuki, T., Suzuki, S., Sakaue-Sawano, A., Miyawaki, A. and Masai, I. E-cadherin controls apical cell geometry and orientation of cell division in the zebrafish lens epithelium. The 35th annual meeting of the Molecular Biology Society of Japan. Fukuoka, Japan. 11–14 December 2012.
Yuasa-Kawada, J., Kinoshita-Kawada, M., Yanagi, S., Masai, I., Rao, Y., and Wu, J.Y. A switch required for axon crossing at the midline: crucial roles of Robo receptor endocytic trafficking and the deubiquitinase USP33. The 35th annual meeting of the Molecular Biology Society of Japan. Fukuoka, Japan. 11–14 December 2012.
Kawada, J., Kinoshita-Kawada, M., Yanagi, S., Masai, I., Rao, Y., and Wu, J. Y. Upregulation of sensitivity to repellent Slit during midline crossing by commissural axons. Joint meeting of the 45th annual meeting of the Japanese society of Developmental Biologists and the 64th annual meeting of the Japanese society of Cell Biology. Kobe, Japan, 28–31 May 2012.


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redpajama_set_name: RedPajamaGithub


text:
The Chariot
Unsung EP
Album length: 6 tracks
Street Date: December 6, 2005
The Chariot has one of the most devout followings in Christian hardcore. The interesting part is that they have only been around a couple of years, and have only released one album. That is, until this, their highly anticipated follow-up, if you can even call it that. In much the same way Mae's Destination: B-sides explained the transition between their debut and The Everglow, The Chariot's Unsung EP takes some of the old and mixes it with some of the new for a delicious appetizer, leading up to what should be a most delectable main course.
The EP begins with the first of two new songs featured on the six track release. It's a bit more structured than Everything Is Alive, Everything Is Breathing Nothing Is Dead and Nothing Is Bleeding, and perhaps a bit more techincally tight. Purists may be put out by the "lack of feedback" and tighter sound, but the carnage and chaos that makes The Chariot such a joy to listen to is still there, and in some aspects seems even more intense. The other new song on the EP, "Kenny Gibler" seems almost, dare I say it, epic, without compromising the Chariot sound.
The other four tracks included on the album are rerecorded versions of tracks from Everything Is Alive.... Seemingly unnecessary, but the reworkings incorporate the maturity the band has experienced over the past couple of years, while granting new drummer Jake Ryan an opportunity to strut his stuff. While nothing can capture to magic that was The Chariot's debut, the rerecordings are memorable.
Also included on the disc is a enhanced CD video of performance in Atlanta at The Masquerade, which rounds off the disc very well with it's depiction of the hardcore carnage we've come to expect from The Chariot. If the Unsung EP is any indication of where this band is going, the future looks very, very bright.
- Review date: 12/6/05, written by Josh Taylor
Record Label: Solid State Records
Buy It: Amazon.com
Yanni Depp
Phil Cosby/Before There Was Atlanta, There Was Douglasville
Vin Affleck/Goodnight My Lady and a Forever Farewell
Kenny Gibler/Play the Piano Like a Disease
Sargeant Savage/Die Interviewer (Germanickly Speaking)
Donnie Cash/The Company, The Comfort, The Grave


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text:
let us discuss Sept. 16, 2016
Let's Talk About the Ending of Bridget Jones's Baby
By Nate Jones
Push! Push! Photo: Giles Keyte/Universal Pictures
Today sees the release of Bridget Jones's Baby, the latest installment of the Bridget Jones Cinematic Universe. As in the previous editions — 2001's Diary and 2004's The Edge of Reason — Baby sees our Bridge torn between two very different men, either of whom could be the father of the eponymous infant. There's Mark Darcy (Colin Firth), of course, the stiff-lipped human-rights lawyer whose demeanor runs the gamut between reserved and aloof, and there's the improbably named Jack Qwant (Patrick Dempsey), an American dating-site billionaire who loves algorithms almost as much as he loves buttoning his shirts to the very top. Early on, Bridget refuses the amniocentesis that would let her figure out which man impregnated her, and so the identity of the true father isn't revealed until the last scene of the film, where we learn …
Spoilers for Bridget Jones's Baby below!
Okay, so: It's clear early on that Bridget is not going to end up with Jack. He's sketched so broadly that he's barely a character, and Dempsey in his initial scenes gives what can only be called a terrible performance. But for most of the second half, the plot seems to be moving toward one particular resolution: Bridget is going to end up with Mark Darcy, whose coldness about the two-dads situation seems to be an obvious case of jealousy, but the biological father is going to be Jack, who is 110 percent into the whole baby thing. That way everybody gets an arc, and we the audience learn a sweet lesson about the nature of family in the 21st century.
Up to and including the penultimate scene of the movie, that's how it looks like things will shake out. After the kid's born, we flash forward to Bridget and Mark's wedding, where Jack is standing in the front row. He's holding the baby and beaming, looking every inch the happy dad. Except, not two minutes later, Mark asks Jack to "give me back my son."
Mark is the father!? (Oh yeah, and the baby's a boy. He's pretty cute.)
It's an odd twist, and it seems to come out of nowhere. Was it added purely for shock factor — or was the shadowy hand of outside interference at work? Evidence in favor of the latter theory comes in another scene, about halfway through the film. While discussing the baby's big feet, Bridget's father (Jim Broadbent) mentions that Bridge has inherited his own exceptionally small feet. At first, this seems like a clue: Could the film subtly investigate which of the suitors gave the baby its big-footed genes? But no — the foot-size conversation simply gets tabled, and it never comes up again.
What gives? Did some executive decide that, if Mark Darcy is Bridget's soul mate, he damn well must also be the dispenser of the champion sperm? Did test audiences hate an ending where Dempsey was the father, and all the foot-related shenanigans that preceded it? And if he's not the dad, why do they let Jack hold the kid at the wedding? Is that the normal consolation prize for dudes who find out they're not the father?
Regardless of what really happened (and yes, I'm prepared to go full truther) the movie's current ending muddles the narrative. Over the course of the film, Mark Darcy is forced to come to terms with what it would mean to love Bridget even while she's pregnant with another man's child. It's a gripping emotional journey, and it's undercut completely by the twist at the end: Turns out Mark doesn't need to work on his jealousy at all. There's also a weird whiff of social conservatism that seems surprising in a film where Bridget invigorates her mother's political career by convincing her to become the candidate of gays, immigrants, and single moms. After a film's worth of lip service to the idea that a family can be whatever you want it to be, the happy ending for Bridget and Mark is still a traditional, biological nuclear family.
bridget jones's baby
let us discuss
Let's Talk the Bridget Jones's Baby Ending


Despite all the hysteria worldwide, Europe and America are now seeing far less immigration than they have had in the past.
Europe had 1 million migrants from across the Mediterranean in 2015. This year Europe has had just 89,000 so far. Just over 18,000 arrived over sea to Italy, an 80% drop since the same time in 2017.
In America, the number of migrants trying to cross our Southern border is now probably the lowest it has been since at least the 1970s.
When Trump became president, more illegal immigrants were moving back to Mexico than entering our country.
In the 10 years before Trump's election, the number of illegal immigrants in the US shrank by over 1 million.
None of the 3 million refugees who have entered this country in the last 40 years has killed anyone in a terror attack. Refugees contribute $63 billion more to our economy than they cost.