The best car maintenance starts at the best auto shop near Baker. Make an appointment at Firestone Complete Auto Care for all your automotive needs today!
Engine knock, oil leak, or low tire pressure, we'll get to the bottom of it. Come to your local Firestone Complete Auto Care with any car problem. You can depend on our knowledgeable technicians to deliver professional auto services near Baker on top of maintenance, oil changes, brakes, car battery tests, alignment, inspections, and more. We know cars and trucks from bumper to bumper, but we also know drivers. That means we'll only recommend services and repairs we believe are a good match for your needs. Besides, we're drivers just like you! Plus, our Triple Promise Guarantee means that your car will be Fixed Right, Priced Right, and Done Right On Time. With 1,700 Firestone Complete Auto Care shops across the country, you should always be close to the right car care at the right time.
We'll help keep things under the hood in working order, but also what keeps you on the road: your tires. Investing in the best truck or car tires can be one of the easiest ways to help keep your vehicle running newer, longer. Whether you want fuel-efficient touring tires or performance sport tires, you'll find some of the best tires for your climate, budget, driving style, and vehicle type. And how about tire pressure checks and flat repairs? You can count on our technicians. Compare tires in-store or online and come to Firestone Complete Auto Care near Baker to help make sure your tires are properly inflated, aligned, balanced, and more. We're a leading tire provider in Minnesota.
Now when it comes to keeping your car running its best, there are two simple things you shouldn't overlook: car batteries and oil changes. Car batteries may be little, but the power they provide is gigantic. When your battery is old or weak, your car may not start. That's where we can help! Stop by Firestone Complete Auto Care for a free car battery test near Baker. A fast test will find out if your car battery is providing enough power and at what temperature it could potentially die. You can also request a car battery test when you stop by for your regular oil change, another service that helps keep your engine healthy. Whether you prefer synthetic blend, synthetic, conventional, or high mileage oil, your car needs new oil at the factory recommended interval, which is typically every 3,000 miles. Fresh, new oil helps keep your engine clean, lubricated, and at its optimum temperature. When it's time for a new battery or quick oil change, come see us. We perform more than 19,000 oil changes every day and install more than 800,000 car batteries a year. Easily book an appointment online and take advantage of our great oil change coupons, tire deals, and service offers. Whether you sit behind the wheel of an everyday sedan or slick sports car, visit your local Firestone Complete Auto Care near Baker today!
From state inspections to spark plug replacement to pothole damage repair, rely on your nearby Firestone Complete Auto Care for your automotive service needs. We're your local car care center, tire store, and automotive shop combined into one. Could caring for your vehicle get any simpler? Our highly qualified technicians believe in truly complete auto care. When you need work done on your car or truck, we promise affordable prices and exceptional service. Explore our offerings below and book an appointment online for auto service near Baker, Minnesota today.


View my new House for sale at 18932 55A AV, Surrey and currently listed at $789,000.
Come have a look at this custom home in a sought after Cloverdale location. Home sits on a 6094sqft southern exposed rear lot with unrestricted views of Mount Baker. Spacious 4000sqft home with quality on all 3 levels and a walkout basement. This home has it all from open ceilings to modern finishings and 2 master bedrooms on the main and upper floor. Finished with all the bells and whistles. Come view this castle and call it "mi casa".


Newport Beach-based Turner Real Estate Investments bought two industrial properties in the heart of Orange County vacated last year by Royalty Carpet Mills Inc. The purchase totaled 546,854 square feet.
Receiving strong interest from e-commerce related operators, the 414,309 square foot property located at 515 East Dyer Road was sold out of escrow to Hines.
TREI will focus on an extensive update of the remaining 132,545 square foot building located at 17352 Derian. As part of the Irvine Business Complex, it is near the Diamond Jamboree shopping center. Anticipated occupancy is January 2019.
It's Turner's largest industrial investment in Orange County in several years.


Mary Jo Lindsey of West Bend, formerly of Theinsville, died peacefully June 10, 2012 at Belgium Gardens, Belgium where she had resided the past two years.
She was born November 12, 1933 in Thiensville, Wisconsin to Melvin and Margaret O'Leary Stowell. Growing up in Thiensville, she attended and graduated from Messmer High School in Milwaukee. She raised her family in West Bend, Wisconsin and worked as a supervisor for Amity Leather Products in West Bend for many years, retiring in 1991. Mary Jo was a caring and proud grandma. She enjoyed cheering on the Brewers and Packers and traveling. She liked to read, sew and craft.
She is survived by her children John Lindsey of Theresa, WI, Kathleen "Bridget" Weiss of Chippewa Falls, WI, Corrine (James) Mikesell of West Bend, WI, Mary (Dave) Leininger of Saukville, WI; grandchildren Patrick and Julie Lindsey, Beth Payne, Jill Schaefer, Laura Remy, Nathan and Erin Weiss, Kaitlin and Shane Jach and great grandchildren Wyatt, Zeviah, Kearsten, Natalee and Abigale. Further survived her sister Margaret "Peggy" (Jerry) Egelhoff of Thiensville, canine pal Maddie, other relatives and friends. She is preceded in death by brothers John and Robert Stowell and sister Virginia "Jean" Taylor.
Reverend Gerald Presuhn will officiate services at NOON Saturday, June 16, 2012 at the funeral home. Visitation Saturday 10 am to Noon on Saturday. Memorials appreciated.
The family sends their deepest thanks to the staff of Belgium Gardens for their wonderful and supported care.


Small, approximately 10-kilobase microhomology-mediated tandem duplications are abundant in the genomes of BRCA1-linked but not BRCA2-linked breast cancer. Here we define the mechanism underlying this rearrangement signature. We show that, in primary mammalian cells, BRCA1, but not BRCA2, suppresses the formation of tandem duplications at a site-specific chromosomal replication fork barrier imposed by the binding of Tus proteins to an array of Ter sites. BRCA1 has no equivalent role at chromosomal double-stranded DNA breaks, indicating that tandem duplications form specifically at stalled forks. Tandem duplications in BRCA1 mutant cells arise by a replication restart-bypass mechanism terminated by end joining or by microhomology-mediated template switching, the latter forming complex tandem duplication breakpoints. Solitary DNA ends form directly at Tus–Ter, implicating misrepair of these lesions in tandem duplication formation. Furthermore, BRCA1 inactivation is strongly associated with ~10 kilobase tandem duplications in ovarian cancer. This tandem duplicator phenotype may be a general signature of BRCA1-deficient cancer.
We thank J. Haber, L. Symington, S. Nik-Zainal and P. J. Campbell for discussions. This work was supported by NCI/DFCI SPORE in Breast Cancer Developmental Research Project Award DF/HCC 5 P50 CA 168504-03 (to N.A.W.), ACS postdoctoral research fellowship PF-12-248-01-DMC (to N.A.W.), R01 ES022054 and R01 CA188032-01 (to E.P.H.), NCI grant P30CA034196 and Andrea Branch and David Elliman Cancer Study Fund (to E.T.L.), grants R01CA095175, R01CA217991, CDMRP OC160440 and HeritX funding (to R.S.), a BIDMC-JAX pilot grant and CDMRP grant BC160172 (to R.S. and E.T.L.). F.W.A. is an investigator of the Howard Hughes Medical Institute.
Department of Medicine, Division of Hematology-Oncology and Cancer Research Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
Boston Children's Hospital, Howard Hughes Medical Institute and Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
Department of Medicine, Flow Cytometry Core, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
N.A.W. and R.S. developed the overall experimental plan. N.A.W. performed or participated in all experiments with the exception of cancer genome analysis. N.A.W. and R.S. planned and designed all the experiments, with additional contributions as follows. HTGTS experiments: plan and design: R.L.F. and F.W.A.; execution: R.L.F. and N.A.W. Cancer genome analysis: plan and design: F.M. and E.T.L.; execution: F.M. Analysis of Brca2 mutant cells: plan and design: E.P.H.; execution: N.A.W. Optimization of FACS analysis and FACS sorting protocols: V.C.; execution: N.A.W. and V.C. Construction and characterization of pHIV lentiviral vectors for expression of Xrcc4: N.A.W., E.E.D., A.P. and R.S. N.A.W. and R.S. wrote the manuscript. Individual figure panels were generated by N.A.W., R.L.F., F.M. and R.S.
Reviewer Information Nature thanks A. Grigoriadis, J. Jonkers, and the other anonymous reviewer(s) for their contribution to the peer review of this work.
BRCA1 suppresses RAD51-independent Tus–Ter-induced GFP–RFP+ repair outcomes.
Examples of breakpoint sequence analysis of Tus–Ter-induced GFP–RFP+ products.
Specificity of BRCA1 loss on Tus–Ter-induced TDs.
Tus–Ter-induced TDs in FANCM- or BLM-depleted Brca1Δ/exon11 6×Ter-HR reporter cells.
BRCA2 is not a major suppressor of Tus–Ter-induced TDs.
Tus–Ter-induced TDs arise by a replicative mechanism involving canonical end-joining.
Breakpoint analysis of Tus–Ter-induced TDs.
Analysis of TD and HTGTS breakpoints.
BRCA1 loss in ovarian and breast carcinomas is associated with widespread TDs of approximately 10 kb (group 1 TDs).
Downregulation of BRCA1 expression is the most prominent and consistent transcriptional feature of ovarian and breast carcinomas associated with TDP group 1 profile.
This file contains gel source data figures.
One type of genomic rearrangement, a microhomology-dependent tandem duplication, is found in BRCA1-deficient but not BRCA2-deficient cells. Using a system to induce replication fork stalling in primary mammalian cells, Ralph Scully and colleagues show how BRCA1 can suppress the formation of tandem duplications at a natural chromosomal replication fork barrier. Interestingly, BRCA1 does not have a similar function during double-stranded DNA break repair by homologous recombination.


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Dark comedy-drama about a group of police working the ugliest streets Manchester has to offer. Keeping the streets clean is a hard task but Inspector Vivienne Deering and her team show they have what it takes to tackle anything criminals can throw at them.
Uni-versalEXTRAS supplied extras and supporting artists for the third series of No Offence TV series.
Civil Servants, Major's Audience, Wealthy Customers, Medical Staff, Market Goers, Passersby With Dogs, Mosque Attendees, Protesters, Traffic Wardens, Tow Truck Assistants, Couples, Counsellors and Lots of Manchester Locals.


Our wildly popular Millefiori yarn got upsized! Millefiori Big blends equal parts wool and acrylic in colorful variegated shades to create projects that are fast and fun to knit or crochet.
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text:
of the Sainte-Justine University Hospital
Hospital & care Learning centre Research Rehabilitation Health Promotion Foundation
Media > News > 2015 > A $6.5-million Canadian Foundation for Innovation funding for CHU Sainte-Justine and Université de M
Monday, June 1 2015
A $6.5-million Canadian Foundation for Innovation funding for CHU Sainte-Justine and Université de Montréal
From gene discovery to treatment of rare diseases and cancers in children in adolescents
MONTRÉAL, June 1, 2015 – The honourable Ed Holder, Minister of State (Science and Technology), announced Friday investment for new research infrastructure through the Canadian Foundation for Innovation, that Canadian researchers across the country will use to advance knowledge. An amount of $6.5-million was allocated to CHU Sainte-Justine and Université de Montréal, partners on the Research Program for Rare Pediatric Diseases RaPiD, a transcanadian pipeline for the discovery, disease phenotyping and mechanism identification, as well as identification of efficient treatment approaches for pediatric rare diseases and cancers, to be conducted in collaboration with University of Ottawa, the Children's Hospital of Eastern Ontario, Dalhousie University and University of British Columbia.
"For children and adolescents with rare diseases or cancers, the first and foremost need is to be diagnosed and adequately cared for," said Jacques Michaud, paediatrician, geneticist and principal investigator of the RaPiD initiative at CHU Sainte-Justine and professor in the Department of Pediatrics at Université de Montréal. "Until now, 50% of patients with rare diseases had no diagnosis at all. This new funding will enable us to accelerate the discovery of genes specifically responsible for each of these approximately 7000 different conditions, and to increase dramatically the pace of treatment development," he continued. Among the rare diseases specifically investigated at CHU Sainte-Justine are brain development disorders including genetic forms of epilepsy and intellectual disability, rare heart diseases and pediatric cancers such as acute lymphoblastic leukemia.
The announced federal funding is pivotal in consolidating genomics research at CHU Sainte-Justine, which is responsible for the diagnosis and treatment of a majority of the most serious childhood diseases in Quebec. It will also help enhance the genomics and bioinformatics core facilities of Génome Québec and CHU Sainte-Justine Integrated Clinical Genomic Center in Pediatrics, and be an invaluable resource for CHU Sainte-Justine Center for Rare Genetic Disorders. These facilities will support genome sequencing and identification of disease causal genes, development of cell models and model organisms for understanding the mechanisms underlying these rare diseases and personalized treatment approaches for the benefit of patients with rare diseases from all over Canada. This infrastructure will support the work of many researchers at CHU Sainte-Justine and of those working in the other institutions forming the RaPiD network.
It is estimated that some 500,000 Canadians collectively have one in about 7,000 rare diseases, for which only approximately 400 therapies are available. Two-thirds of rare diseases are serious and disabling, with over half of them being life-limiting, and 80% appearing early in life. About 30% of children with rare diseases will die before their fifth birthday.
Mélanie Dallaire (French-speaking media)
Senior Advisor, Media Relations, CHU Sainte-Justine
514 345-7707 (direct line)
514 415-5727 (media pager)
melanie.dallaire.hsj@ssss.gouv.qc.ca
William Raillant-Clark (International and English-speaking media)
International Press Attaché, Université de Montréal
w.raillant-clark@umontreal.ca
Communications, Centre de recherche du CHU Sainte-Justine
marise.daigle@recherche-ste-justine.qc.ca
Persons mentioned in the text
Jacques L. Michaud
About CHU Sainte-Justine Research Center
CHU Sainte-Justine Research Center is a leading mother-child research institution affiliated with the Université de Montréal. It brings together more than 180 research investigators, including over 90 clinicians, as well as 350 graduate and post-graduate students focused on finding innovative prevention means, faster and less invasive treatments, as well as personalized approaches to medicine. The Center is part of CHU Sainte-Justine, which is the largest mother-child center in Canada and second most important pediatric center in North America. More on research.chusj.org
Updated on 6/1/2015
Created on 6/1/2015
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Thank you for your generosity.
It's people like you that allow us to accelerate research and heal more children better every year and, as such, offer among the best healthcare in the world.
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text:
Home / gaming
Yasai Ninja Review
By Christian Law @claw3821 4 years ago
Review of: Yasai Ninja Review
gaming:
Christian Law
Reviewed by: Christian Law
Last modified:July 27, 2015
Casting vegetables as heroes can't save Yasai Ninja from sluggish combat, terrible audio-visual design and outright broken programming.
Ninjas have permanently imprinted themselves on popular culture in pretty much every way, shape and form. From assassins to pandas, anything with a sword and a six minute mile can become a ninja. While we can now add vegetables to that list, it might be for the best that we don't, since Yasai Ninja doesn't imprint itself on the world of ninjas in the slightest, but if you've ever wondered how agile and lithe an onion and a stalk of broccoli can be, this is the game for you.
Following the aforementioned onion's quest for vengeance, Yasai Ninja pairs the stoic veggie, named Kaoru Tamanegui, with a sentient stalk of broccoli fittingly named Broccoli Joe. Kaoru is out to defeat his former leader because he turned evil, and Joe is hungry. Plot's not exactly a huge factor here, as you can probably tell.
In the course of ten thankfully short missions, the pair fight their way through an admittedly stylish feudal Japan, trekking across boring environments that are animated in a style that doesn't quite fit the rest of the game. The art style was most reminiscent of the Afro Samurai video game from a few years ago, only filtered through a PS2 rather than a next-gen console. Surprisingly, I found myself enjoying the traditional Asian music as well, although that only lasted until the short clip ended and paused before looping back to the beginning. Around the hundredth time, I started to realize that the music sounds oddly similar to what would be playing in every Chinese buffet in the midwest.
If you've noticed that I haven't mentioned anything about the actual gameplay yet, that's just because there's not really much to say. Yasai Ninja is a third-person hack-and-slasher, and it's not a very good one. Both Kaoru and Joe are extremely sluggish brawlers, and control inputs for both light and heavy attacks feel like they take years to translate to actual action. The first time I took a swing at an enemy, my jaw literally dropped at the delay. Neither character is particularly agile, so switching from one to the other quickly becomes a futile task.
About 90% of the baddies you'll face throughout your journeys are cucumbers, all of which turn into slices when you defeat them, even if it's with Joe's nunchucks. Adding to the frustration of sluggish combat is terrible hit detection and downright awful sound design, leading to enemies turning themselves into sliced snacks without a single noise or even direct hit. You never realize just how much you rely on sound cues to let you know you're connecting with an enemy until the sound drops out entirely.
That being said, Yasai Ninja is hardly a difficult game. In fact, most of my deaths were caused by my horrendous AI partner. I watched the AI fall into lava, throw themselves into armies of baddies and constantly fall on spikes until they died, leaving me to either heal them or instantly sending us back to the last checkpoint. If the player loses all of their health, they have to wait for their partner to come heal them before they can get back into the action. However, rather than switching to your partner so you can come heal yourself or finish the fight on your own, you have to sit and stare at the screen until the AI deems you worthy of being saved. I understand this mechanic being utilized in multiplayer, but in single player it becomes a glaring and infuriating oversight.
Sometimes the action is broken up by running segments that are slightly reminiscent of the treasure chest levels from the past few Rayman titles, albeit not as fun or visually striking. While these levels tend to function normally, they're hardly ever challenging, with much of the difficulty stemming from the art design getting in the way of the gameplay. For some reason, most of these levels aren't lit very well, making jumping from a thin ledge onto another an obnoxious task. Other times, the back beam of a bridge will follow the exact line of the platforms, making it indistinguishable between the next ledge you're aiming for. I died countless times trying to figure out what was a platform and what was in the background.
There are also tons of pedestals to push and machines to activate or dismantle, although there are never any puzzles or actual thought put into these diversions. One segment in particular matched certain buttons to segments of a spike trap, insinuating you would need to hit the right combination to get them all to go down. Instead, all you needed to do was push all three buttons once and you were done. It was just as exhilarating as it sounds.
As I mentioned before, there are only ten stages, making Yasai Ninja an easy title to breeze through if you have the patience. However, I only made it to stage seven before I gave up. Multiple times throughout that level (which was fittingly titled In Hell), the game simply crashed, throwing up an error screen and sending me back to the PS4 home screen. At one point, I had finally reached the boss of the level, and right before I could defeat it, the game once again crashed, sending me back to the very beginning of the level I had just spent an hour playing over and over again. Not only is the game poorly made, it's just plain broken.
I would never be ignorant enough to assume that every single copy of the game will play just like mine did, but Yasai Ninja is simply impossible to recommend based on my experience with it. Even without it crashing to the point where progress was impossible, it was just a messy experience that didn't even have a clever idea behind it. Veggie ninjas could be interesting, but not once does it enhance the plot or lead to some clever, cheesy puns. Everything is played incredibly straight-faced without even an ounce of levity, making it just another generic ninja-revenge story as performed by vegetables.
Here's the rundown: the gameplay is bad, the sound design is bad, the controls are bad, the story is bad, the actual programming is bad, and the art is occasionally good. Aside from turning bland characters into bland vegetables, Yasai Ninja has nothing to offer. No original thought has been put into the design, the writing is bland exposition, and much of the game hardly works. I had hoped to find some quirky little gem hiding behind a neat idea that would balance humor with a short jaunt of arcadey action. Rather, I got a month old onion lazily thrown at my face.
This review is based on a PlayStation 4 version of the game, which was given to us for review purposes.
Tags: gaming reviews, Reviews, yasai ninja


text:
<?php

declare(strict_types=1);

/*
 * This file is part of the RollerworksSearch package.
 *
 * (c) Sebastiaan Stok <s.stok@rollerscapes.net>
 *
 * This source file is subject to the MIT license that is bundled
 * with this source code in the file LICENSE.
 */

namespace Rollerworks\Component\Search\Extension\Core\ValueComparator;

use Rollerworks\Component\Search\ValueComparator;

/**
 * Default ValueComparator implementation, only able to compare equality.
 *
 * @author Sebastiaan Stok <s.stok@rollerscapes.net>
 */
final class SimpleValueComparator implements ValueComparator
{
    public function isHigher($value, $nextValue, array $options): bool
    {
        return false;
    }

    public function isLower($lower, $higher, array $options): bool
    {
        return false;
    }

    public function isEqual($value, $nextValue, array $options): bool
    {
        // This does not work for objects, so they should have
        // there own comparison classes.
        return $value === $nextValue;
    }
}

redpajama_set_name: RedPajamaGithub


kernel/bpf/verifier.c in the Linux kernel through 4.14.8 ignores unreachable code, even though it would still be processed by JIT compilers. This behavior, also considered an improper branch-pruning logic issue, could possibly be used by local users for denial of service.
The check_stack_boundary function in kernel/bpf/verifier.c in the Linux kernel through 4.14.8 allows local users to cause a denial of service (memory corruption) or possibly have unspecified other impact by leveraging mishandling of invalid variable stack read operations.
kernel/bpf/verifier.c in the Linux kernel through 4.14.8 allows local users to cause a denial of service (memory corruption) or possibly have unspecified other impact by leveraging the lack of stack-pointer alignment enforcement.
kernel/bpf/verifier.c in the Linux kernel through 4.14.8 allows local users to cause a denial of service (memory corruption) or possibly have unspecified other impact by leveraging improper use of pointers in place of scalars.
kernel/bpf/verifier.c in the Linux kernel through 4.14.8 allows local users to cause a denial of service (integer overflow and memory corruption) or possibly have unspecified other impact by leveraging unrestricted integer values for pointer arithmetic.
kernel/bpf/verifier.c in the Linux kernel through 4.14.8 allows local users to cause a denial of service (memory corruption) or possibly have unspecified other impact by leveraging incorrect BPF_RSH signed bounds calculations.
kernel/bpf/verifier.c in the Linux kernel through 4.14.8 allows local users to cause a denial of service (memory corruption) or possibly have unspecified other impact by leveraging mishandling of 32-bit ALU ops.
kernel/bpf/verifier.c in the Linux kernel through 4.14.8 allows local users to cause a denial of service (memory corruption) or possibly have unspecified other impact by leveraging register truncation mishandling.
The check_alu_op function in kernel/bpf/verifier.c in the Linux kernel through 4.14.8 allows local users to cause a denial of service (memory corruption) or possibly have unspecified other impact by leveraging incorrect sign extension.
The KEYS subsystem in the Linux kernel before 4.14.6 omitted an access-control check when adding a key to the current task's "default request-key keyring" via the request_key() system call, allowing a local user to use a sequence of crafted system calls to add keys to a keyring with only Search permission (not Write permission) to that keyring, related to construct_get_dest_keyring() in security/keys/request_key.c.
The HMAC implementation (crypto/hmac.c) in the Linux kernel before 4.14.8 does not validate that the underlying cryptographic hash algorithm is unkeyed, allowing a local attacker able to use the AF_ALG-based hash interface (CONFIG_CRYPTO_USER_API_HASH) and the SHA-3 hash algorithm (CONFIG_CRYPTO_SHA3) to cause a kernel stack buffer overflow by executing a crafted sequence of system calls that encounter a missing SHA-3 initialization.
The Salsa20 encryption algorithm in the Linux kernel before 4.14.8 does not correctly handle zero-length inputs, allowing a local attacker able to use the AF_ALG-based skcipher interface (CONFIG_CRYPTO_USER_API_SKCIPHER) to cause a denial of service (uninitialized-memory free and kernel crash) or have unspecified other impact by executing a crafted sequence of system calls that use the blkcipher_walk API. Both the generic implementation (crypto/salsa20_generic.c) and x86 implementation (arch/x86/crypto/salsa20_glue.c) of Salsa20 were vulnerable.
The usb_destroy_configuration function in drivers/usb/core/config.c in the USB core subsystem in the Linux kernel through 4.14.5 does not consider the maximum number of configurations and interfaces before attempting to release resources, which allows local users to cause a denial of service (out-of-bounds write access) or possibly have unspecified other impact via a crafted USB device.
net/netfilter/xt_osf.c in the Linux kernel through 4.14.4 does not require the CAP_NET_ADMIN capability for add_callback and remove_callback operations, which allows local users to bypass intended access restrictions because the xt_osf_fingers data structure is shared across all net namespaces.
The __netlink_deliver_tap_skb function in net/netlink/af_netlink.c in the Linux kernel through 4.14.4, when CONFIG_NLMON is enabled, does not restrict observations of Netlink messages to a single net namespace, which allows local users to obtain sensitive information by leveraging the CAP_NET_ADMIN capability to sniff an nlmon interface for all Netlink activity on the system.


text:
All issues Volume 63 / No 2 (July 2003) Europhys. Lett., 63 2 (2003) 247-253 Abstract
Volume 63, Number 2, July 2003
Condensed matter: structure, mechanical and thermal properties
https://doi.org/10.1209/epl/i2003-00520-y
Thermophoresis in protein solutions
S. Iacopini and R. Piazza
INFM, Dipartimento di Ingegneria Nucleare, Politecnico di Milano via Ponzio 34/3, 20133 Milano, Italy
Received: 7 April 2003
Thermophoresis, unlike thermal diffusion in simple mixtures, consists in particle drift induced by a temperature gradient . We show that thermophoresis in lysozyme solutions has a very distinctive behavior: particle motion can indeed be tuned from "thermophobic" (towards the cold) to "thermophilic" (along ) by decreasing T. The observed temperature behaviour weakly depends on electrostatic effects, and rather suggests a primary role of hydrophobic interactions, further supported by comparison with the temperature dependence of lysozyme equilibrium solubility. Most of the observed features can be qualitatively understood by envisaging thermophoresis as a "microscopic Marangoni effect", due to thermally induced gradients of the interfacial free energy.
PACS: 66.10.Cb – Diffusion and thermal diffusion / 82.70.Dd – Colloids / 87.15.Nn – Properties of solutions; aggregation and crystallization of macromolecules
The "macromolecular tourist": Universal temperature dependence of thermal diffusion in aqueous colloidal suspensions
Eur. Phys. J. E (2006) 19: 59-67
Influence of temperature and charge effects on thermophoresis of polystyrene beads⋆
Eur. Phys. J. E (2016) 39: 129
How does thermodiffusion of aqueous solutions depend on concentration and hydrophobicity?
Eur. Phys. J. E (2014) 37: 94
Eur. Phys. J. E (2004) 15: 233-234
Do thermal diffusion and Dufour coefficients satisfy Onsager's reciprocity relation?


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text:
So, The South Carolina Debate Was A Hot Mess
Story from News
The South Carolina Debate Was A Hot Mess — Here's What Happened
Leora Yashari, Natalie Gontcharova
Photo: Mario Tama/Getty Images.
All eyes were on South Carolina Tuesday night for another heated Democratic presidential debate, this time between seven candidates: Former VP Joe Biden, Sen. Bernie Sanders, former Mayor Pete Buttigieg, Sen. Elizabeth Warren, Sen. Amy Klobuchar, as well as billionaires Tom Steyer and Michael Bloomberg.
Biden is clearly the crowd favorite in South Carolina — walking into the Gaillard Center in Charleston, we saw a huge group of his supporters waving signs and dancing to "Turn Down For What" — and is expected to win the state, considering his history here and influential endorsements from politicians such as Rep. Jim Clyburn (who announced his endorsement Wednesday morning after the debate).
But with Super Tuesday coming up next week, everyone was watching the candidate who has racked up the most delegates so far: Sanders, who recently won the Nevada caucuses. It was unsurprising that Sanders was a target of virtually all of the other candidates at tonight's debate. After Bloomberg agreed to release women from his company's NDAs at Warren's urging, we were also watching for the Massachusetts senator to again take him to task for his treatment of women.
It was a rather messy debate with no clear winners. Ahead, we've mapped out all of the biggest moments from the South Carolina debate.
Elizabeth Warren backs up Bernie's progressive ideas (but says she'd make a better president).
"Bernie and I agree on a lot of things, but I think I would make a better president than Bernie," because she has the details and tenacity to enact her progressive agenda, says Warren, who's been making this argument for a while, particularly as it relates to getting to universal healthcare. "I dug in. I did the work. And then Bernie's team trashed me for it," she pointedly says about her plan for Medicare for All. Pete Buttigieg adds that if we think America's divisive now, wait until we have a Trump vs. Bernie showdown. "Imagine spending the better part of 2020 with Bernie Sanders vs. Donald Trump."
Gayle King grills the candidates on stop and frisk.
Gayle King came prepared to ask tough questions tonight, and she immediately turns the attention to Bloomberg's history with stop and frisk in New York City. King says that although Bloomberg has apologized for stop and frisk, she wants to know exactly what he is apologizing for. "We let it get out of control and when I realized that, I cut it back by 95%," Bloomberg responds. "And I've apologized and asked for forgiveness. I've met with Black leaders to try to get an understanding of how I can better position myself and what I should have done and what I should do next time." Then, Mayor Pete — who himself has faced criticism on race relations — has a bit of a hero moment, calling out the fact that every candidate on the debate stage is white.
Bloomberg swoops in with the urgent news that he has met black human beings and that they've reported a phenomenon known as "racism"
— Sady Doyle (@sadydoyle) February 26, 2020
Warren hammers Bloomberg on his comments to women and NDAs — again.
After she talks about her experience with pregnancy discrimination, Warren calls Bloomberg on allegedly having told a coworker to "kill it" when finding out she's pregnant, which he claims he never said. Bloomberg then says he thinks he's done enough by releasing women at his company from their NDAs, purporting that he's never been accused of making more than a "joke" that he "probably" shouldn't have made. For Warren, this isn't enough — the senator who has gone after Bloomberg's history of offensive comments about women is planning to continue holding him accountable at every turn.
Gayle King asked Warren for evidence that Bloomberg told a pregnant woman to "kill it." Not only was that the woman's testimony, a third party witness — the kind Bloomberg said in a deposition he required for an assault claim — backed it up to Wapo https://t.co/v9f9qT82Rw pic.twitter.com/KgigO7KoZr
— Irin Carmon (@irin) February 26, 2020
Bernie Sanders: "Here's how we're going to pay for it."
Bernie Sanders released a document detailing how he's going to pay for Medicare for All and other plans earlier this week. When the moderators ask him about his spending plans, the other candidates pile on about why they don't believe they're realistic. It's the first of many moments in the night when Sanders, as the frontrunner, is targeted.
Warren says Democrats won't get gun reform passed without abolishing the filibuster.
Every debate: Warren is the only one who brings up nuking the filibuster. Every time, I say this is the most important thing. Every spin, the media ignores.
— Elie Mystal (@ElieNYC) February 26, 2020
Amy Klobuchar brings up her bill to close the boyfriend loophole.
Amy Klobuchar praises her bill calling to close the "boyfriend loophole," which is a legislation gap allowing physically abusive dating partners and ex-boyfriends with convictions to continue accessing guns. Biden immediately takes credit for it — although after some heated back-and-forth, they establish that he wrote the Violence Against Women Act (the boyfriend loophole is an amendment to VAWA).
Bloomberg thinks he won the last debate...?
If you don't live in NYC, here's what Bloomberg meant when he mentioned the Naked Cowboy.
Bloomberg seems to be full of jokes tonight, and one of them is a shoutout to New York's infamous Naked Cowboy — a Times Square staple. For those outside of NYC, the Naked Cowboy is an actor and singer who performs in Times Square wearing only a cowboy hat, tighty-whities, and a strategically placed guitar.
If you had "Uncle Dick in the deer stand" or the "Naked Cowboy" on your #DemDebate bingo card, consider yourself a winner. https://t.co/xFDf5zkKPK
— Twitter Moments (@TwitterMoments) February 26, 2020
Bernie Sanders wants to legalize marijuana on day one.
Sanders is famously the pro-weed candidate — and his position is not necessarily shared by everyone on stage. Bloomberg, for instance, says that we should decriminalize possession of small amounts, but that there's not enough research to make it completely legal everywhere. All of the marijuana talk sets off a lively debate on criminal justice, and then it comes back to Bernie, who says: "We will change the Federal Controlled Substance Act, which, if you can believe it, now equates heroin with marijuana. That's insane." He adds: "We're going to provide help to the African-American, Latino, Native American community to start businesses to sell legal marijuana, rather than let a few corporations control the legalized marijuana market."
The candidates discuss the coronavirus.
Moderators ask the candidates how they would handle the coronavirus outbreak. Klobuchar stresses that Americans should educate themselves by understanding how the CDC is handling the coronavirus, while Biden blames Trump for cutting funding of the CDC.
Bernie & Pete spend a full two minutes screaming over each other.
Several of the candidates (but mostly Pete Buttigieg) continue to criticize Bernie for "praising" authoritarian leaders after his comments about Fidel Castro's regime have angered some, particularly in the Cuban community in Florida. Bernie has clarified that he does not condone Castro's authoritarian tactics, but simply stated the fact that he increased literacy in his country. As Buttigieg keeps digging, Bernie can't seem to get a word in, and the two end up screaming over each other for what seems like an eternity (even debate moderators could not get a word in during their simultaneous rants).
Bernie's team hit back on Pete for his comments.
Wait ... is it bad to have nostalgia for the revolutionary politics of the 1960s Pete?
I'm seem to recall Black people fighting for and securing some important rights during that revolutionary period. #DemDebate
— Briahna Joy Gray (@briebriejoy) February 26, 2020
Bernie & Bloomberg are asked about their plans for Israel as the only Jewish candidates on stage.
Bernie says that he is proud of being Jewish, but there is a "reactionary racist" running Israel in the form of Benjamin Netanyahu. "I happen to believe that what our foreign policy in the Mideast should be about is absolutely protecting the independence and security of Israel, but you cannot ignore the suffering of the Palestinian people." Bloomberg, the other Jewish candidate on stage, says the "only solution here is a two-state solution." He also speaks against moving the American embassy back from Jerusalem to Tel Aviv.
Candidates close out the debate by listing their personal mottos outside of politics.
Tom Steyer: "Every day, I write a cross on my hand to remind myself to tell the truth and do what's right, no matter what."
Amy Klobuchar: "Politics is about improving people's lives."
Joe Biden: "When you get knocked down, get up. And everyone is entitled to be treated with dignity, no matter what, no matter who they are. Also, that everyone should be represented," he says, adding that he wants to make sure there is a Black woman on the Supreme Court — so far there have been zero.
Bernie Sanders: "Everything is impossible until it happens." (Quoting Nelson Mandela.)
Elizabeth Warren: "Inasmuch as ye have done it unto one of these, the least of thy brethren, ye have done it unto me." (Quoting Matthew 25.)
Pete Buttigieg: "I seek to live by the teachings that say if you would be a leader, you must first be a servant. And, of course, the teaching, not unique to the Christian tradition, but a big part of it, that holds that we are to treat others as we would be treated."
Mike Bloomberg: "I've trained for this job for a long time and when I get it I'm going to do something rather than just talk about it."
South Carolina Democratic Debate: Winners & Key Moments
News • 2020 Election • The Latest • Politics • US News
written by Leora Yashari
written by Natalie Gontcharova
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<transcripts>
<transcript id="10" title="Healthy Recipes- Blueberry Protein Pancakes " url="https://www.youtube.com/watch?v=FaPX7_KslTo" mode="non-automatic">
I'm Natalie Hodson, here today in the bodybuilding.com kitchen showing you how to make a recipe that I make a lot of mornings, and it's my <entity type="Recipe">Blueberry Protein Pancake</entity>.<s>
This is a really good recipe.<s>
If you're getting tired of the same old <entity type="Ingredient">egg whites</entity> and <entity type="Ingredient">oats</entity>.<s>
This uses the exact same ingredients.<s>
It just mixes them into a different way.<s>
I know there's a lot of protein pancake recipes out there, but I like this one because it uses all whole foods and it tastes really good.<s>
These are all the ingredients that we're gonna use for today's recipe.<s>
We're gonna use <entity type="Amount">6</entity> <entity type="Ingredient">egg whites</entity>, and <entity type="Amount">1/2</entity> <entity type="Unit">cup</entity> of old fashion <entity type="Ingredient">oats</entity>.<s>
I like the old fashion <entity type="Ingredient">oats</entity> better than the <entity type="Ingredient">instant oats</entity> just because they're a little bit less processed.<s>
The <entity type="Ingredient">instant oats</entity> have actually been cooked and dehydrated to make them cook faster, and these haven't.<s>
They've just been rolled.<s>
We have <entity type="Amount">1/4</entity> <entity type="Unit">cup</entity> of <entity type="Ingredient">blueberries</entity>.<s>
You can use fresh or frozen or you can substitute it for raspberries or strawberries.<s>
We have <entity type="Amount">1/2</entity> <entity type="Unit">cup</entity> of <entity type="Ingredient">unsweetened vanilla almond milk</entity>.<s>
And just make sure that when you get the <entity type="Ingredient">almond milk</entity>, you're getting the unsweetened vanilla kind.<s>
I like the Almond Breeze brand.<s>
It's 40 calories, has no sugar in it.<s>
Also, if you wanted, you could substitute milk, but I prefer the <entity type="Ingredient">almond milk</entity>.<s>
And then we have <entity type="Amount">1</entity> <entity type="Unit">teaspoon</entity> of <entity type="Ingredient">baking powder</entity>.<s>
This is just to help the pancakes rise a little bit.<s>
<entity type="Amount">Two</entity> <entity type="Unit">packets</entity> of <entity type="Ingredient">Truvia</entity>.<s>
This is to make them a little bit sweeter.<s>
I have <entity type="Amount">1/2</entity> <entity type="Unit">cup</entity> of <entity type="Ingredient">unsweetened applesauce</entity> and just <entity type="Amount">a</entity> <entity type="Unit">dash</entity> of <entity type="Ingredient">cinnamon</entity>.<s>
And those two items we're gonna save 'til the end and use it as a topping on top of the pancakes.<s>
So for today's recipe, I'm actually gonna use a blender to mix everything together.<s>
And I'm gonna start with my liquid ingredients.<s>
Gonna pour in my <entity type="Ingredient">almond milk</entity>, and then I'm going to do my <entity type="Ingredient">egg whites</entity>.<s>
And I'm just gonna crack these right into the blender.<s>
Now some people just throw their yolks away into the trash can.<s>
I actually like to put mine in the garbage disposal, and I found that out the hard way.<s>
I used to just throw my yolks into the trash can, and one day I came home and my house smelled really bad and I couldn't figure out why.<s>
And it's because I left the yolks in the trash can for too long, and so now what I do is I'll just put them right into the garbage disposal.<s>
Some people like to feed the egg yolks to their dog, and I guess that helps with their coat and makes it a little bit shinier.<s>
And this is a really good breakfast recipe if you have kids.<s>
I have a 2 year-old and he loves this recipe.<s>
We eat it a couple times a week.<s>
And it's a really good way to incorporate some whole grains into their diet, and the <entity type="Ingredient">blueberries</entity> has some really good antioxidants.<s>
Another thing you can do is you can make these in bulk on the weekend, and then freeze them.<s>
I think they taste a little bit better fresh but you definitely can freeze them.<s>
And when I do that I just put them in a Ziploc bag and then when I wanna eat them, I stick them in the microwave for about a minute.<s>
Alright.<s>
So we have <entity type="Amount">6</entity> <entity type="Ingredient">egg whites</entity>.<s>
Then I'm just gonna add my <entity type="Ingredient">oats</entity>.<s>
And I'm gonna save the <entity type="Ingredient">blueberries</entity> until we're actually in the griddle.<s>
I'm gonna add my <entity type="Ingredient">baking powder</entity>.<s>
I'm just gonna do <entity type="Amount">a</entity> <entity type="Unit">dash</entity> of <entity type="Ingredient">salt</entity>.<s>
It's probably about <entity type="Amount">1/8</entity> of a <entity type="Unit">teaspoon</entity> if you were to measure it.<s>
And then <entity type="Amount">two</entity> <entity type="Unit">packets</entity> of <entity type="Ingredient">Truvia</entity>.<s>
If you want to eat the pancakes without any applesauce on top, you could add <entity type="Amount">a third</entity> <entity type="Unit">pack</entity> of <entity type="Ingredient">Truvia</entity>.<s>
It would make your pancakes sweet so you wouldn't need to add the applesauce on top.<s>
And then I'm just gonna blend this really fast.<s>
Alright.<s>
I'm quickly gonna turn my skillet on to about medium-high heat.<s>
Then I'm just gonna spray it with a little bit of non-stick cooking spray.<s>
And then I'm just gonna take my batter and--this recipe makes two pancakes.<s>
Two pancakes is one serving so usually just kinda eyeball it.<s>
And put about half of the batter in the skillet, and then I'm gonna take <entity type="Amount">half</entity> of my <entity type="Ingredient">blueberries</entity> and just drop them in the top.<s>
You can blend these, the <entity type="Ingredient">blueberries</entity>, in too if you want.<s>
I've done that before, but I think it tastes a little better this way.<s>
Makes them a little bit juicier.<s>
So we're just gonna let this cook.<s>
Usually you can tell they're ready to flip when there's bubbles in the center of the pancake.<s>
So I went ahead and flipped the pancake.<s>
We've been cooking it about 1 to 2 minutes on each side.<s>
And sometimes the first pancake doesn't flip quite as well as the second pancake, and it's because sometimes in the blender the <entity type="Ingredient">egg whites</entity> tend to kinda stay at the top and the oats fall to the bottom, but this one turned out pretty good.<s>
So I'm just gonna take the pancake and put it on my plate.<s>
I'll flip it I guess.<s>
That side's not quite as pretty.<s>
And then I'm gonna go ahead and put my second pancake in.<s>
I'm just gonna blend it for just a second to get everything shaken up.<s>
Gonna spray my pan with the spray.<s>
Then I'm just gonna pour the rest of my batter in.<s>
Make sure to get all those <entity type="Ingredient">oats</entity> out.<s>
And I'm gonna add the rest of my <entity type="Ingredient">blueberries</entity>.<s>
And we're just gonna let it cook about 1 to 2 minutes per side.<s>
You know it's ready to flip once the edges look like they're cooked all the way through and there's bubbles starting to form in the center of the pancake.<s>
Alright.<s>
So we are done cooking our second pancake.<s>
I'm gonna go ahead and put it on the plate.<s>
Oops.<s>
As you can see, this is a lot of food.<s>
This is another reason I like this recipe is 'cause it's really great way to start the day with a nice hearty meal.<s>
And then--the pancakes are really sweet on their own I think, and so a lot of times I'll actually eat these even without any applesauce on top.<s>
You can use <entity type="Ingredient">sugar free syrup</entity> if you want, but I prefer to stay away from that just because it has a lot of preservatives in it.<s>
So sometimes if I want a little extra something on top, I'll use <entity type="Amount">some</entity> <entity type="Ingredient">unsweetened applesauce</entity>.<s>
Just make sure you get the <entity type="Ingredient">applesauce</entity> that says no sugar added or unsweetened or if you read the ingredient list, the only ingredients are apples, water, and maybe ascorbic acid which helps keep the coloring.<s>
So I'm just gonna go with this <entity type="Amount">half</entity> of a <entity type="Unit">cup</entity> of <entity type="Ingredient">applesauce</entity>.<s>
I'm just gonna pour it on top.<s>
Sometimes I like to put a little bit underneath.<s>
And then I like <entity type="Ingredient">cinnamon</entity> so I'm gonna put <entity type="Amount">a</entity> <entity type="Unit">dash</entity> of <entity type="Ingredient">cinnamon</entity> on top.<s>
You don't have to do that if you don't like cinnamon.<s>
Sprinkle a little <entity type="Ingredient">cinnamon</entity> on top and there you go.<s>
You have a really good breakfast.<s>
One serving is 2 pancakes, and each serving has <entity type="Amount">6</entity> <entity type="Ingredient">egg whites</entity>, and <entity type="Amount">1/2</entity> a <entity type="Unit">cup</entity> of <entity type="Ingredient">oats</entity>, <entity type="Amount">some</entity> <entity type="Ingredient">blueberries</entity>, and <entity type="Amount">some</entity> <entity type="Ingredient">almond milk</entity>.<s>
So to get this <entity type="Recipe">Blueberry Protein Pancake</entity> recipe, you can check out the link on the page below, and continue to go to bodybuilding.com to find all of my other recipes as well as nutritional information, workout programs, and motivation.<s>
</transcript>
</transcripts>


text:
PhD Thesis Defense by Mustafa Ütkür
Cancer Imaging and Treatment Monitoring With Color Magnetic Particle Imaging
Mustafa Ütkür, Ph.D. in Electrical and Electronics Engineering
Advisor: Assoc. Prof. Emine Ülkü Sarıtaş
Date and Time: September 06, 2021, 11:30 a.m
Zoom Access Link: https://zoom.us/j/6454523840?pwd=NWovV0JDbnFIZExqamlYYzkxWEI4UT09
Magnetic particle imaging (MPI) is emerging as a highly promising non-invasive tomographic imaging modality for cancer research. Superparamagnetic iron oxide nanoparticles (SPIONs) are used as imaging tracers in MPI. By exploiting the relaxation behavior of SPIONs, the capabilities of MPI can also be broadened to functional imaging applications that can distinguish different nanoparticles and/or environments. One of the important applications of functional MPI is viscosity mapping, since certain cancer types are shown to have increased cellular viscosity levels. MPI can potentially detect these cancerous tissues through estimating the viscosity levels of the tissue environment. Another important application area of MPI is temperature mapping, since SPIONs are also utilized in magnetic fluid hyperthermia (MFH) treatments and MPI enables localized application of MFH. To achieve accurate temperature estimations, however, one must also take into account the confounding effects of viscosity and temperature on the MPI signal. This dissertation studies relaxation-based viscosity and temperature mapping with MPI, covering the biologically relevant viscosity range (<5 mPa·s) and the therapeutically applicable temperature range (25-45˚C). The characterization of the SPION relaxation response was performed on an in-house arbitrary-waveform magnetic particle spectrometer (MPS) setup, and the imaging experiments were performed on an in-house MPI scanner. Both the MPS setup and the MPI scanner were designed and developed as parts of this thesis. The effects of viscosity and temperature on relaxation time constant estimations were investigated, and the sensitivities of MPI to these functional parameters were determined at a wide range of operating points. The relaxation time constants, 𝜏's, were estimated with a technique called TAURUS (TAU, 𝜏, estimation via Recovery of Underlying mirror Symmetry), which is based on a linear relaxation equation. Although the nonlinear relaxation behaviors of the SPIONs are highly dependent on the excitation field parameters, SPION type, and the hardware configuration, the results suggest that one-to-one relation between the estimated 𝜏 and the targeted functional parameters (i.e., viscosity or temperature) can be obtained. According to these results, MPI can successfully map viscosity and temperature, with higher than 30%/mPa/s sensitivity for viscosity mapping and approximately 10%/˚C sensitivity for temperature mapping, at 10 kHz drive field frequency. In addition, the results suggest that the simultaneous mapping of viscosity and temperature can be achieved by performing multiple measurements at different drive field frequencies and/or amplitudes. Overall, these findings show that hybrid MPI-MFH systems offer a promising approach for real-time monitored and localized thermal ablation treatment of cancer. The viscosity and temperature mapping capabilities of MPI via relaxation time constant estimation can provide feedback for high accuracy thermal dose adjustment to the cancerous tissues, thereby, increasing the efficacy of the treatment.
Key words: Magnetic particle imaging, superparamagnetic iron oxide nanoparticles, nanoparticle relaxation, temperature mapping, viscosity mapping


It's no secret at this point that a high level of emphasis on data collection and analytics should be a pivotal part of every business' strategy. For any corporate leader that wants to better understand consumers, improve marketing strategies and lock in more sales, it's vital to have a comprehensive approach to gathering data and using it.
There are a lot of questions to answer throughout this process, though. One of them pertains to data quality - it can be difficult for companies to ensure the information they're working with meets a high standard for accuracy and usability, especially when they're trying to work quickly and avoid wasting any time or money. In this regard, it's important for companies to make efficient use of customer data a top priority.
Perhaps the most important, overarching question is this - what's the best way to get real value from data? After all, every company out there is putting significant effort and funding into analytics, and it's not enough just to be one of those faces in the crowd. To really make an impact, you need to have a strategy that gets better results than anyone else. You need to do more with less.
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There are opportunities to improve in this area. B2C also cited research from data insight company ClickFox, which discovered that about 32 percent of consumers are "most willing to share personal data if they feel loyal to a brand." There's definitely an opening for companies to improve their data strategies.
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Along those lines, here are three ways to get more out of a customer data strategy.
The most advantageous thing about data-driven customer relationships is they can help customers find the information that matters most to them. Whether it's about what products they might like, how they can purchase them cheaply or what technology they should use, people always appreciate useful knowledge. Companies can use their data to explore how to make their customers more informed.
Is there a specific problem that consumers have that makes it difficult for them to grow into more loyal customers? Are your products too expensive, or are they not finely tuned enough to people's needs? The whole point of selling a product is to satisfy consumers' tastes. Gathering better data can help gauge what those tastes are, making it easier to connect with people on a more authentic level.
Companies can best take advantage of data when they're working in a free-flowing environment, with information moving seamlessly on both sides. When companies engage easily with customers, and the customers willingly respond, everyone benefits. The primary goal should be to nurture an environment where everyone shares knowledge freely, working together to improve both the customer experience and a company's bottom line.


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I was turned into the Hayward Shelter as a stray. I was friendly, outgoing and playful, but every once in a while I would do my "trick." People found that upsetting, and it eventually got me labeled as "unadoptable." Nobody's Perfekt Dogs took me in to see if there was a solution for my "trick."
They think I was probably mercilessly teased in my former home. It caused me great stress, and I coped by doing my trick. People probably thought my trick was cute, so they teased me more so that I would do it. My trick is that when I am stressed, I chase my tail - not in a playful way, but in an aggressive way. I don't catch it or bite it. I don't do it for very long, but I have been known to do it multiple times, back-to-back. I am on medication to help with stressful times, but I do the best with no other dogs around and in a quiet home.
When I am not doing my trick (which is most of the time), I love playing with toys, especially fetching a small ball. I could do that for hours. I like getting attention, being on a lap, getting treats. I am good on a leash and I use pee pads it I don't have access to go outside. I like all kinds of people and I don't bark much.


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Artists to Napa's di Rosa center: Selling collection 'would lead to an irretrievable loss'
Charles Desmarais August 20, 2019Updated: August 22, 2019, 1:28 pm
Enrique Chagoya, "When Paradise Arrived" (1988) is among the works at the di Rosa Center for Contemporary Art. Photo: di Rosa, Napa
More than 125 prominent artists, gallerists and others have signed an open letter to leaders of the di Rosa Center for Contemporary Art, protesting a plan to sell most of the center's famed collection.
The letter states that the signatories "express our opposition to the dismantling and commercial sale of the di Rosa Collection." It asks that the center's board and director identify "an alternative institution to house, preserve, and appropriately utilize this unique collection."
Mark di Suvero's "For Veronica" (1987), at di Rosa. Photo: Faith Echtermeyer / di Rosa, Napa
Among those who had signed the letter as of noon Tuesday are more than 60 artists whose work is included in the collection, a unique repository of late-20th century Northern California art. They include many of the most celebrated figures associated with the region, among them Terry Allen, Luis Cruz Azaceta, Deborah Butterfield, Squeak Carnwath, Enrique Chagoya, Mark di Suvero, Mildred Howard, Robert Hudson, Paul Kos, Lynn Hershman Leeson, James Melchert, Richard Misrach, Ron Nagle, Richard Shaw and William T. Wiley. Representatives of the estates of Robert Arneson, Wallace Berman, Joan Brown, Jay DeFeo and Mel Ramos also signed.
The letter expresses concern for what it calls "the only collection in the world dedicated exclusively to the history of post-World War II art in Northern California in all its diversity of media, gender, race, and philosophy," and it pointedly makes the case that artists helped to build it.
Joan Brown's painting "Girl Standing" is among the works in the di Rosa collection. Photo: di Rosa, Napa
"The collection was borne from the relationships Rene and Veronica di Rosa had with the artists and curators of the Bay Area," it states. "The collection benefited from those relationships in the form of gifts of work or substantially discounted purchases made with all participants in agreement that the acquisitions were to be part of a museum collection, meaning that they would be properly stored, conserved, made available for viewing, loans, and exhibition."
On Wednesday Robert Sain, the director of the di Rosa center, responded with a letter that repeated claims that the center did not have sufficient funds to maintain the collection. "It would … have been wonderful if additional donors beyond our board, membership, and strong base of supporters had responded to our fundraising efforts," he wrote.
The letter cites what it calls an "unfortunate" circumstance, "that we finally had to face the reckoning … or close our doors forever."
This article has been updated to include the response from the di Rosa Center for Contemporary Art, and to include copies of the original letters.
Following are the two letters, as received by The Chronicle:
Charles Desmarais
Charles Desmarais Charles Desmarais is The San Francisco Chronicle's art critic. Email: cdesmarais@sfchronicle.com Free weekly newsletter: http://bit.ly/ArtguyReviews
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Two things drove this particular Forgotten Film post. First, since good friends and colleagues Paula (of Paula's Cinema Club) and Kevin (aka Jack Deth) hosted and contributed handsomely to the recent What A Character blogathon with another wonderful piece (this time spotlighting actor Richard Jaeckel), I thought it appropriate to dust off an old look-back article of mine for a film the three of us love. And second, it's in keeping with the World War II theme my duo-post partner Rachel and I will have going for the close of September.
It was the summer of '67, and remains keen even in this old-ish mind of mine. I being a dozen years old back then became highly aware of — and secretly wanted to be as cool as — the actor Lee Marvin. The moment remains crystal. Heading over to the Warner Theatre in Huntington Park as June turned into July that year, I became mesmerized to that very fact as I took in Robert Aldrich's The Dirty Dozen. Growing up, every kid I knew had seen Marvin plenty of times before in reruns of M-Squad. Plus, his guest appearances as the heavy-of-the-week on TV shows of the time (Rawhide, Bonanza, etc.) and older movie westerns (Comancheros, The Man Who Shot Liberty Valance, and others) only added to the exposure.
Yet, it was in this action/war film that the real impression of Marvin, the man, was gauged. At least by me. Here was where that no-nonsense aura of good ol' American red-blooded maleness was ingrained into my susceptible pre-teen psyche. I'll stipulate for the record that being tough/cool then was a hyper-dimensional shift away from what that means today. It was definitely a more masculine era ages ago (for better or worse). Plainly, what courses as the contemporary equivalent need not apply.
From that point on in the summer of 1967, if Lee Marvin was in a film, I had to see it. Whether it was on television or the movie theater, it was a given. Having caught films like Richard Brooks' rousing western The Professionals, or the earlier and highly underrated war drama, Attack, which was also directed by Aldrich, as TV fare was nothing to sneeze at. More so if it was on the big screen with the likes of Point Blank, Monte Walsh, Prime Cut and others.
Personally, I place Lee Marvin in the same class of actor as the great Robert Mitchum, skill and reputation-wise. Both were the type of actor who could effortlessly pull off their roles as rugged, dangerous, but oh so self-possessed men. Marvin and Mitchum seemed cut from the same cloth in that regard. There certainly was no shortage of testosterone when these guys were in the room (or on-screen). Each of them was a man's man (yes, an old maxim, if there ever was one… but it still fits here).
After viewing The Dirty Dozen, I could only imagine if guys were going into battle, they'd want someone like Lee Marvin as their squad leader (he being a former Marine from WWII, in actual fact). And they'd, beyond question, dread having him as their nemesis, as well (especially, if he was leading their squad). When I remember this actor, I instantly think of him in the role of Major John Reisman, right along with this one-of-kind war film.
If there's one film that served as the template for 'men on a mission' movies, I'd have to nominate The Dirty Dozen as it. Like some of the big pictures of the period, it had an extraordinarily rich cast. Besides Marvin, it boasted as having the sturdy likes of Charles Bronson, Ernest Borgnine, John Cassavetes, George Kennedy, Robert Ryan, Ralph Meeker, Clint Walker and early significant roles for the budding talent of Donald Sutherland and the football legend Jim Brown. Add to this a rousing style instilled by the filmmakers that brought the actors on the screen to the full and cheering clamor of the audience.
The film's director would mine a similar subversive level a few years later, featuring the same undisguised and rebellious ferocity, with 1974's The Longest Yard (and don't get me started on the lame Adam Sandler remake of 2005). Still, nothing packed a wallop like this wartime actioner. Robert Aldrich's films historically celebrated a defiant individualism, and had a decidedly anti-establishment bent to them. Obviously, The Dirty Dozen was no exception. Even amongst the humor and action of the piece, there is an intense disdain of authority at its core and in its telling of the behind the lines (and somewhat gonzo) pre D-Day raid it depicted.
That much was certainly clear since the film's military leadership (represented so snakily well by Borgnine and Robert Webber as the generals in question) handed Reisman what amounted to a suicide mission for his fealty. By today's standards, its violence is not that shocking. Still, the high body count made for a good bit of criticism by some when it was first released. The efficient, and almost carefree, manner our merry dozen go about eliminating German soldiers (especially the officers) at its climax was probably a point of pride for the filmmaker. That didn't stop it from being popular with the movie-going public, though.
Far from it. Especially, as the Vietnam War was really beginning to boil to the forefront at the time. We, the movie patrons, could eat it up without too much cynicism since Tet was still months away. Regardless, visually it remains an amazing experience for those who've seen it in a movie theater. It's tailor-made for the big screen. What's interesting to note is the film was originally released in a blown up 70mm format called "Metroscope". As good as today's high-definition Blu-ray Discs and flat-panel home theater set-ups can be, this is one of those motion pictures, if you'd ever get the chance to view it in a movie hall, that's not to be missed.
A couple of years back, The Dirty Dozen and Attack were on the bill for the Robert Aldrich Double Feature event for a Memorial Day weekend screening by the American Cinematheque Los Angeles. While I have this film on DVD and BD, catching it on the big screen once again was a treat beyond measure. Not only did it showcase a true rebel, a highly underrated director far too many of today's young moviegoers and filmmakers overlook, it demonstrated how great this old film (it turned 45 this year), and the screen presence of one Lee Marvin, really was.
Let it be said though, director Quentin Tarantino gave this film an indirect homage with his vigorously dialogued and unique take of the genre in 2009's Inglourious Basterds. While it was a wilder remake of this '78 war film, which was itself a poor man's version of Aldrich's, both movies had their similarities. However, as much as Brad Pitt tried, his Lt. Aldo Raine will always take a backseat to Marvin's Major Reisman, in my opinion. That said, I did get to re-encounter The Dirty Dozen in the same historic movie theatre where I first saw The Empire Strikes Back 30 years prior. And well, that turned out to be just icing on the cake.
Thank you very much, Tyson.
Excellent as always Michael. It's been too long since I've seen this classic.
Yes, this is a film that's so entertaining, yet with Robert Aldrich's sense of things, that's worth periodic screenings. Thanks, Mark.
Fantastic write-up. Love this film and watch it every so often. Whenever I do it reminds me of my grandfather who was a big Lee Marvin fan and the times I would watch it with him as a kid. Good times.
Agreed! These guys are definitely cut from the same cloth and really embodied what it meant to be a man.
Thank you very much, J.D. I certainly can understand your experience with the film and the Lee Marvin fan that was your grandfather. This is a film and that readily lends itself to such memories.
I haven't seen this movie in a long, long time. Now, thanks to you, I'm going to have to borrow it from my local library and watch it.
Oh, yeah! Teeing this one up is something I well support. Many thanks, John.
Thanks so much for the fine introduction. 'The Dirty Dozen' ranks very high in my personal category of 'Guy Flicks'. Led by the always intriguing tough guy, Lee Marvin. No other actor handled a rifle or pistol with such familiarity, respect and ease.
Great cast. Believable plot and superbly executed story. In one of the first and best of the 'Badass genre', which Mr. Marvin and many of his ensemble were made for!
Always my pleasure to give you a shout-out, my friend. Yes, this is one of the ultimate 'Guys Flicks', alright. As you state, Lee Marvin was "always intriguing" and a "tough guy". He did handle weapons effortlessly and naturally, didn't he? Thanks, Kevin.
Robert Aldrich and Lee Marvin – two great favourites of mine! The machismo, grit and cool cynicism fairly pummel you into submission, and leave you wishing it could keep on coming.
They did fit and work together well, didn't they?
Truer words, Colin. Many thanks.
Michael, you give such great context for the films you write about. This makes it a richer experience when I see them again 🙂 I sort of thought QT was alluding to THE DIRTY DOZEN in Raine's first scene in INGLOURIOUS BASTERDS. I'm so far from being the target audience for both IB and DIRTY DOZEN. After some thought, I've decided that in addition to enjoying a good action picture, I just like seeing the Nazis lose.
You're very kind, Paula. Love this comment! We're definitely in the same boat with your statement ;-). Thank you so very much.
I love Lee Marvin's voice. I think it adds intensity to the films he is in.
Great point, Marianne. Lee Marvin's voice could denote so much, and he used it so very well in whatever he did (TV or film). As a villain or hero, the man was somethin'! Thank you, Marianne.
Great look at this movie… I dont know that it's forgotten… well, maybe it is. But the title stuck in pop culture. Now its a famous phrase! The movie will always have that association!
Great quote to bring up, Fogs! And it did have one Hell of a cast.
I did go round and round about calling it a forgotten film. Ten, fifteen years ago I'd never have considered that. It remains well known among the fans of the director and lead actor. Yet, when Tarantino's film, IB, debuted the talk of 'Inglorious Bastards' from '78 (a source of the remake) seemed to stop there without giving due to what Aldrich accomplished with 'The Dirty Dozen' the previous decade. That basically told me, now 45 years later, that younger moviegoers were kinda of ignoring such older, great fare like this. Hence, I included it as something I wanted to spotlight and not have anyone 'forget'.
Thanks so much, my friend, for the deft comment.
One of the great war movies of all time. I really don't think it was forgotten though. Maybe somewhat overlooked next to the Magnificent Seven and Seven Samurai but I think a lot of people appreciate this film's greatness.
Please reference what I said to Fogs about this point. Yes, I readily admit this film, among certain groups of movie fans, this is far from a forgotten film. Yet, as more time passes amid today's younger audiences, 'The Dirty Dozen' is something they (perhaps) have heard of, but haven't seen. Lee Marvin, same. Robert Aldrich, less so. And that's really unfortunate. Just my way of promoting and appreciating the set. Thanks for reading and the comment, my friend.


Bacharova L, Mateasik A. Bacharova L, Mateasik A Bacharova, Ljuba, and Anton Mateasik.Chapter 11. Dipolar Electrocardiotopography Imaging. In: Pahlm O, Wagner GS. Pahlm O, Wagner G.S. Eds. Olle Pahlm, and Galen S. Wagner.eds. Multimodal Cardiovascular Imaging: Principles and Clinical Applications New York, NY: McGraw-Hill; 2011. http://accessmedicine.mhmedical.com/content.aspx?bookid=382&sectionid=40663662. Accessed April 19, 2019.
Bacharova L, Mateasik A. Bacharova L, Mateasik A Bacharova, Ljuba, and Anton Mateasik.. "Chapter 11. Dipolar Electrocardiotopography Imaging." Multimodal Cardiovascular Imaging: Principles and Clinical Applications Pahlm O, Wagner GS. Pahlm O, Wagner G.S. Eds. Olle Pahlm, and Galen S. Wagner. New York, NY: McGraw-Hill, 2011, http://accessmedicine.mhmedical.com/content.aspx?bookid=382&sectionid=40663662.
The vector principle is the basic principle of electrocardiography for the interpretation of the standard 12-lead electrocardiogram (ECG) as well as for teaching.1 However, its application in the interpretation of the standard 12-lead ECG is demanding for a mental three-dimensional imagination, and the "mental image" requires linking the orientation and magnitude of the vector to the anatomy of the heart, its position in the chest, and the sequence of activation (Fig. 11–1).
A. The scheme of the hexaxial coordination system of the standard 12-lead electrocardiogram (ECG). B. The short axis view (right) and long axis (left) view of magnetic resonance imaging (MRI). The mental three-dimensional image that would include the structural (MRI) and functional (ECG) characteristics of the heart and their temporo-spatial relations is too complicated.
Vectorcardiography partially reduces these problems. It presents the distributed electric field at every instant of time by a dipole—the equivalent dipole. This dipole is represented by a vector, defined by its magnitude and orientation, theoretically corresponding to the extent of the activation front and its location. The origin of the dipole is fixed in the center of an orthogonal coordinate system, and the trajectory of the end point of the vector during the atrial/ventricular depolarization and repolarization depicts the spatial vectorcardiographic loop. The classical graphical presentation of vectorcardiography is the planar vectorcardiogram—the planar projection of the spatial vectorcardiographic loop onto three perpendicular planes: the frontal, sagittal, and horizontal (transverse) planes.
Compared with the standard 12-lead ECG, the orthogonal ECG does not contain redundant information. The coordinate system of the orthogonal ECG/vectorcardiogram may be aligned with the geometry of the heart and to our knowledge about the sequence of atrial and ventricular activation. These characteristics make the vectorcardiogram instrumental for teaching the principles of ECG diagnosis, as well as for comparative studies with other imaging methods. However, the interpretation of vectorcardiograms is demanding for three-dimensional imagination and for good orientation in the anatomic structures and their relationships to the processes in the heart. In addition, these graphical presentations—scalar tracings of orthogonal ECG and planar vectorcardiogram—are not directly comparable with images of the heart developed from another imaging method.
In this chapter, we describe a method for graphical presentation of the orthogonal ECG/vectorcardiogram that allows the visualization of the vectors representing the cardiac electrical field comparably to other imaging methods used in cardiology. This graphical presentation of ECG is suitable for side-to-side comparisons as well as for superimposition or fusion of information from multiple imaging modalities.


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Nickel prices poised for a rebound – by Biman Mukherji (Wall Street Journal – March 9, 2015)
March 9, 2015 in Asia Mining, International Media Resource Articles, Nickel, Nickel Laterites
http://www.wsj.com/
PRICES of nickel hit their lowest levels in more than a year last week, suggesting it is just another metal suffering from weaker Chinese demand growth and a strong dollar.
But many traders and analysts think the long decline in nickel's price is reaching an end, as China's drive to produce more of a substitute product — nickel pig iron — shows signs of cracking. NPI is commonly used in China as a cheaper alternative to pure nickel for producing stainless steel.
China's burgeoning output and usage of NPI has meant that the world has had plenty of spare pure nickel. That has put pressure on prices for the commodity: the benchmark three-month nickel futures contract on the London Metal Exchange is down around 30 per cent in the past year.
For more than a year, Chinese producers of nickel pig iron have countered an export ban on the nickel ore they need from their largest supplier, Indonesia, by drawing upon stockpiles of the ore they built up just before the ban was imposed in early 2014. But now China's stockpile of nickel ore is running short: stocks in five of the country's main ports have halved within one year, according to Commerzbank.
As the ore hoard runs down, Chinese stainless-steel producers will likely have to import more pure nickel, putting upward pressure on prices.
Moreover, tougher anti-pollution laws in China are forcing low-grade NPI producers to close. Some NPI producers have already shut down because low prices have made them economically unviable. In total, China's NPI production could fall by as much as 12 per cent this year, Commerzbank forecasts.
Factor in an expected rise in global stainless-steel production — Commerzbank reckons output will grow by 5 per cent — and the conditions for a resurgence in nickel prices look to be in place.
A rally would make nickel stand out in a depressed picture for global metals. Iron ore has continued its slide this year to multimonth lows, while copper and aluminium prices remain in the doldrums.
The price of nickel futures on the London Metal Exchange, which touched its lowest level in more than a year, at $US13,610 a tonne, in intraday trading Wednesday, rebounded to $US14,370 Friday on increased talk about NPI smelter closures.
For the rest of this article, click here: http://www.wsj.com/articles/nickel-prices-look-poised-to-rebound-1425848978
'India poised to be world's 3rd largest economy' (Business Standard – March 9, 2015)
NEWS RELEASE: SAMSSA: The growth of a Mature Mining Cluster in Northern Ontario – by Dick DeStefano (March 9, 2015)


For young and middle-aged adults, going out and socializing is often associated with drinking. Not everyone drinks with the intention of harming themselves or others. But even social drinking can become problematic when we don't know when to stop.
The realization that alcohol consumption is a problem can be devastating. Many people believe that because alcohol is legal, they should be able to enjoy it without having to suffer any adverse consequences. But you don't have to be addicted to alcohol to find yourself facing unpleasant consequences from . The belief that excessive social drinking or alcoholism is a character flaw or weakness only serves to compound the problem. A tailspin of guilt, fear, and shame often results when these common misconceptions come face-to-face with the desire to enjoy some adult beverages while out having a good time.
Consider the statistics: Alcohol is the most in the U.S., and approximately 18 million Americans are affected by alcohol-related problems. In 2010 nearly 26,000 people (not including homicides or accidents) died from alcohol-related causes. conducted in 2006 revealed that excessive drinking cost the U.S. more than $223 billion.
Despite these significant statistics, it's possible to enjoy social activities or relax at home without the abuse of alcohol. Educating yourself on alcoholism and to drink in moderation are ways to maintain your health and well-being.
Monitor your intake. Before going out, it's important to decide how many alcoholic servings to enjoy. Pace is also important; rather than downing three drinks in one hour, it's wiser to enjoy a few drinks over the course of a few hours.
Enlist friends and family. Those who find themselves repeatedly drinking too much may need to examine their social circles to see if excessive drinking is being encouraged. A good friend will be happy to help us cut back on drinking.
Set a limit; keep track. Men should aim to no more than three to four ounces, which is typically three to four shots, of alcohol daily, while women should limit themselves to two to three ounces. Bring a pen and mark your hand with how many drinks you've had to avoid getting carried away, which easily happens when we're having fun. You can also ask a friend to help you keep track of the amount you've consumed. Additionally, keep track of how many consecutive days include drinking as part of your social life. Everyone should have a minimum of two alcohol-free days per week. for 48 hours after getting drunk and or out of control.
Eat and stay hydrated. Eating and drinking water should precede or be part of any social event where drinking alcohol is involved. Drinking on an empty stomach can lead to quicker alcohol absorption. It's also wise to drink a pint of water before each alcoholic beverage is consumed to avoid dehydration.
Focus on the benefits of not drinking. Thinking about the of being and feeling healthy can actually make people drink in moderation or avoid alcohol altogether. Start by putting together a list of 10 ways in which being alcohol-free feels better. Post the list where it can be seen daily. In addition, put your focus on enjoying healthier alternatives not involving drinking alcohol.
Even if an individual is cutting back rather than quitting, it's best to take the process one day at a time. From the first six hours to a few weeks after a last drink, medium to heavy drinkers can experience , including twitching, cold sweats, anxiety, and difficulty sleeping, eating and concentrating. By ending alcohol consumption, they may see a difference in the puffiness of their face. Their fatigue and lethargy will disappear, forcing . After a few months, excess weight begins to disappear as the . Although most people don't realize it, alcohol, especially beer, adds up to a lot of calories and can easily add pounds to the body.
Those affected by excessive alcohol consumption or abuse often feel the task of overcoming it is hopeless. But there is hope for an individual, family member or friend who desires to enjoy alcohol more responsibly or quit it, altogether. Follow the steps and tips shared here to cut back on alcohol consumption. If drinking has become a problem the individual is no longer able to control, it's best to reach out to a trusted family member or friend, mentor, or someone at a rehab center who can help them begin the process of breaking free from alcohol addiction.
This post was written by guest contributor , founder of , a rehabilitation center that helps people overcome drug addictions through holistic, natural methods. All views and opinions expressed in the piece are his. To learn more about Per, follow him on and , or at his website .


Having originally formed at university with members Harry Sullivan and Charlie Hawkins from Bengal Lancers, originally started life as a Leicester-based two-piece. Armed with little more than a wealth of covers and a smattering of originals, it wasn't long before ambition saw the duo enlist drummer Max Hutchi, and relocate to the Capital.
Now a four-piece, and a band in the truest sense of the word, their relocation allowed their talent to blossom, while the addition of fourth member Aidan Wickham saw their trademark sound flourish, becoming the encompassing brand of alt-rock the band peddle today.
With a small collection of singles and two EPs under the beat, the releases of which were all met with acclaim, it's clear that Bengal Lancers are making all the right noises and have the medals to prove it.
The band is now set to release their next single 'Eclipse', which is their first exciting offering into 2018. 'Eclipse' stands out fearlessly and packs with a wonderful blend of adventurous lyrical storytelling and progressive instrumental approaches leading into a stellar climax of raucous rock moments. It's something to behold.
'Eclipse' explores confusion and chaos that surrounds the break-down of a relationship, but still harbouring the glimmer of optimism that's so often clung to in such situations. Check it out below.
Bengal Lancers will release new single Eclipse on January 26th 2017.