Radical Cystectomy for Bladder Cancer in Patients With and Without a History of Pelvic Irradiation: Survival Outcomes and Diversion-related Complications.
Nguyen, Daniel P; Al Hussein Al Awamlh, Bashir; Faltas, Bishoy M; O'Malley, Padraic; Ayangbesan, Abimbola; Inoyatov, Igor M; Scherr, Douglas S.
Urology; 86(1): 99-106, 2015 Jul.
Recurrence patterns after open and robot-assisted radical cystectomy for bladder cancer.
Nguyen, Daniel P; Al Hussein Al Awamlh, Bashir; Wu, Xian; O'Malley, Padraic; Inoyatov, Igor M; Ayangbesan, Abimbola; Faltas, Bishoy M; Christos, Paul J; Scherr, Douglas S.
Eur Urol; 68(3): 399-405, 2015 Sep.
ICl-induced intramolecular electrophilic cyclization of 1-[4'-methoxy(1,1'-biphenyl)2-yl]alkynones--a facile approach to spiroconjugated molecules.
Chen, Yu; Liu, Xiaochen; Lee, Minwook; Huang, Chenlong; Inoyatov, Igor; Chen, Zhiwei; Perl, Abraham C; Hersh, William H.
Chemistry; 19(30): 9795-9, 2013 Jul 22.


? Part of this wiki because he challenges anti-white migration policies and the islamization of Europe.
He's the far-right activist who has made Holocaust-denying statements and was recently pictured with Katie Hopkins in Sicily.
r/ChapoTrapHouse - The folks over on Peter Sweden twitter are having a brawl over being pro-giant mushroom immigration or anti-giant mushroom immigration.


text:
Children Were Gods And Bitches Got Dysentery: Oregon Trail, For Those Too Young To Remember
Posted in Entertainment, GSOY (Gratuitous Story of Yourself) by Molly
When was the last time you went to a magic lantern show? Or a melodrama? And liked it? Some forms of entertainment don't hold up over time. Imagine a curly-mustached Victorian fop trying to convince you that no, seriously pantomimes are riveting. That's how it feels explaining Oregon Trail to people who were too young to live it firsthand. But now that Oregon Trail is available to play online, there are going to be a lot of folks in the 23-and-under* crowd trying to understand the fuss – so I'll make an effort.
The Life And Times Of '80s and '90s Kids
I call this costume 'Annie Hall Of Green Gables.'
I've mentioned this before, but there was this weird trend in the early-mid 90s that nobody ever talks about. It's not leggings or crop tops, which if anything are over-represented in 90s nostalgia. No, it was this thing where it was sort of normal for a child to be into the 1800s. A new version of Little Women came out, those American Girl books were everywhere, and moms watched Dr. Quinn. The Indian In The Cupboard was surprisingly popular. Craft books taught you how to make yarn dolls like Laura Ingalls. We were standing on the cusp of the digital age, playing with doll-sized butter churns.
In addition to old-timey pursuits like microwaving popcorn right on the cob just like they did in Colonial Williamsburg, us early millennials were the first generation to use computers as soon as we started school. Well, they were less like computers and more like giant graphing calculators. The screens were all-black with green or orange lettering and simple line graphics. A big part of every computer class was booting up your computer – not because it was exciting, but because it took ten minutes. Those of us who were lucky had Nintendo at home, and later, maybe a Sega system. Still, computer games were new and exciting and required "floppy disks." There weren't many choices, but kids and lazy substitute teachers alike loved Oregon Trail. Adults appreciated that it was educational – in that it provided a one-sided view of Manifest Destiny, I suppose. And kids loved it, because it represented a world …
Where Children Were Gods
I once read that youngest children are drawn to animals because they enjoy having someone that they could be the boss of. As a youngest child, I'd argue that we just liked being around living things that couldn't pick on us, but I digress. Sometimes a kid does like being in charge of things. Every game of Oregon Trail was a tiny, horrifying example of what would happen if kids ruled the world – like a virtual Lord Of The Flies.
You would think that the goal of any game would be to win it. That discounts just how cruel and terrible children can be. Sometimes, you'd play just to see how disastrous you could make the lives of the characters. Here's how:
You were allowed to name the wagon party. That meant that the most common names in Oregon Trail character history were probably Poop, Butt, Jesus and (Sibling's Name) Sucks.
You'd become a dreadful taskmaster, especially if the game handed you a low-income profession. The harshest sentence? Grueling pace and meager rations. That's also the title of my future memoirs. And with that burden, it's no wonder that…
Bitches got dysentery. And bitches who get dysentery get buried under a solitary rock along the roadside before we continue on our journey. Sorry, Butt.
"I tried to ford the river and my f***ing oxen died." That was one of the biggest Facebook groups of the 2004-2006 era, and a universal experience during Oregon Trail's heyday. When you got to the river you could hire a local to ferry it across, caulk the wagon, or sort of just hurl yourself headlong into the river. That's how I remember it anyway. And I always found myself thinking, shouldn't we have figured this out before we got to the damn river?
We killed the American Buffalo. When you'd go hunting, those slow-ass buffalo mosied across the screen, leaving you ample time to shoot them. You'd kill every buffalo that ambled by. Then, you'd be informed that you could only bring 100 pounds of meat into your wagon and had to leave all that buffalo carrion to fester in the prairie sun. We knew that would happen. We just wanted to hear the hollow thud when they died. Children are sick. Someone, please make a horror movie in which all of the events of the Westward Expansion – including the near-extinction of the buffalo – were under the control of 7-year-old Kimberly in Miss Smith's computer class in 1992.
Ain't No Party Like An Oregon Trail Party Cuz An Oregon Trail Party Proffers a Tombstone Generator When You Die From Pooping Too Much
On one hand, children were pioneer overlords in Oregon Trail – but on the other, the cruel hand of fate was always at play. It was like the game of Life, but instead of teaching children that you may fritter your life away in middle-management at a bank, it taught you that sometimes you do your best and thieves still steal all of your oxen in your sleep. Even if you played the game the "right way," giving your settlers proper Oregon Trail names like Rebecca and Amos and setting a pace that would get you to Oregon before winter without killing you from exhaustion (before it was the trendiest cause of celebrity hospitalization), there were no guarantees that you'd arrive in the promised land. The dream of the 1850's was alive in Portland – but would you be alive to see it? Here are some ways you could die:
Snakebite
Broken limbs
Failing to save your progress at the end of a class period.
Godspeed, 90s kids. You have a 40-minute computer class ahead of you, and your teacher has laryngitis. During that time you may reach the promised land, and you may die from drinking river water. And even if you live, PoopfaceJesus may not. Oh, cruel world.
*This probably varies depending on how outdated your school's computer game library was.While later versions of Oregon Trail came out on CD-ROM, I think that after the early-mid 90s, there were more games to chose from and Oregon Trail was no longer the only, um, ox on the prairie? So to speak.
90s, 90s kids, computer games, MS-DOs, nostalgia, oregon, oregon trail, video games 7 Comments
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Home > Conversations in Integration > Two cheers for the Global Compact
Two cheers for the Global Compact
By Rebekah Smith
The draft Global Compact on Migration is surprisingly ambitious – but will it be implemented?
The Trump administration withdrew the United States from the talks last December. Hungary's authoritarian nationalist government threatened to pull out too. But the Global Compact for Migration (GCM) is going forward without the US – and its current draft is a surprisingly progressive document.
The international community now has an unprecedented opportunity to shape the future of migration. Negotiations to finalise the GCM, which opened last month, aim to produce an agreement for signature by the end of the year. A new "zero draft plus" was published yesterday and the second round of intergovernmental negotiations start on 12 March. As it stands, the draft comprises 22 objectives for "safe, orderly and regular migration," each underpinned by tangible commitments. But the deal is not done yet. And since it is non-binding, ensuring it is implemented will be a huge challenge.
The wins
The most important advance in the current text is the recognition and acceptance of the need for "options and pathways for regular migration in a manner that reflects demographic and global labour market realities." This includes tangible commitments to introduce new legal pathways for regular migration, an unprecedented step at the international level. Underlying this statement is an understanding that migration is bound to increase in coming years (as I explain in another OPEN piece). That is a significant shift from the stance of many receiving countries that seek to deter migration by addressing its drivers (though these attempts also feature in the document as noted below).
The GCM is similarly forward-looking in recognising the need to create pathways for predictable movements of people in response to climate change. It commits to developing "tailored migration schemes of various duration… to facilitate migration as an adaptation strategy to slow-onset environmental degradation." New Zealand became the first country to introduce such a scheme when late last year it introduced a climate refugee visa for Pacific Islanders likely to be displaced in the near future. But there has otherwise been little recognition of, or preparation for, the masses of people likely to be displaced by climate change.
While affirming the principle of national sovereignty, this GCM also implicitly works towards balancing it with the sovereignty of the person. It supports the decriminalisation of irregular border entry (making irregular entry an administrative, not a criminal, offence). It also commits states to save lives and prevent migrant deaths regardless of legal or entry status. This extends to relegating migrant detention to a measure of last resort. Given that the last few years have been full of horror stories of lives lost from the lack of such protections, it is good that the GCM seeks to value migrant lives properly.
The losses
But while the current draft of the GCM recognises the need to open new legal pathways for migration, it also includes an entire section on "minimis[ing] the adverse drivers and structural factors that compel people to leave their country of origin." This not only contradicts the spirit of the document, which recognises migration as bringing benefits and prosperity to all. It is also based on the fallacy that economic development at home can deter voluntary migration, as Marta Foresti remarks and Michael Clemens and Hannah Postel point out.
More broadly, the GCM could benefit from a deeper emphasis on the agency of migrants themselves and the incentives they face. While its proposals are progressive, they still generally focus on the factors and systems influencing migrants, rather than migrants' agency in shaping their own future. For example, the section on recruitment reiterates existing international conventions insisting on zero-fee recruitment. These conventions position migrants as victims of exploitation, while ignoring their own decision making in what is essentially a market exchange for services.
What is this all likely to mean? For the moment not much. As it is stands, the Compact is a non-binding agreement that includes tangible commitments but no tangible implementation plan. Of the Compact's 25 pages, less than one is on implementation (and even this is far from clear). So even if all the progressive commitments make it into the final document, how can one ensure they are rolled out on the ground?
With 22 objectives, each with five or more commitments, it is obviously impossible to do everything at once So what is needed is a coordinated action plan across states and actors with clear priorities and benchmarks.
One priority should be practical innovations that could offer results without requiring difficult policy changes, such as Michael Clemens' proposal for a Global Skills Partnership. This leverages differentials in the cost of training and skilled wages across countries to facilitate skills mobility while simultaneously increasing the skills base in both sending and receiving countries. Low-hanging fruit such as this should be prioritised, while supported by the more difficult long-term policy changes.
Implementing the GCM will also require innovative financing mechanisms. As international migration is by definition a cross-border issue, states may be loath to invest in such mechanisms on their own. Receiving states (for example) can benefit significantly from the investments made by origin countries on their sending systems. A Joint Financing Facility, similar to that put forward by the International Civil Aviation Organisation here, could make it easier and more politically feasible to develop a realistic action plan.
While the GCM has put forward a surprisingly progressive vision for the global governance of migration, it remains to be seen whether this vision is reflected in the final text. Governments also need to recognise that implementing the Compact will require an action plan and commitment mechanisms. Even so, against the backdrop of so much negative news about migration, it is cheering that the global community has recognised migration as a "source of prosperity, innovation and sustainable development in our globalised world."
Source: Reprinted from Open Political Economy Network (OPEN), Two Cheers for the Global Compact, March 6, 2018
Rebekah Smith is is a development consultant specialising in designing migration policies, particularly in South Asia-Middle East corridors. She is an alumna of the Harvard Kennedy School of Government.
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text:
Q: Restrict editText from accepting alphabets (in java)? I defined an EditView in Java and set it to accept numbers. Then it is accepting numbers only, but I needed float values so changed it to following code:
final EditText eQuantity = new EditText(getActivity());
                eQuantity.setHint("Enter Quantity here");
                eQuantity.setInputType(InputType.TYPE_NUMBER_FLAG_DECIMAL);

But now it is also accepting alphabets along with float values. Am I missing something over here?

A: try as:
eQuantity.setInputType(InputType.TYPE_CLASS_NUMBER |
                InputType.TYPE_NUMBER_FLAG_DECIMAL |
                InputType.TYPE_NUMBER_FLAG_SIGNED);

redpajama_set_name: RedPajamaStackExchange


Easter is 3 days after Good Friday. It is also a day of celebration, because Jesus died for everyone's wrongdoings, but 3 days later, He rose again!
You probably have question marks on your faces, but basically, Jesus was resurrected and pretty much came back from the dead. He was able to do this because he is the Son of God and he was able to conquer everything – even death!!


text:
Title: Broth
Subject: Sorrel soup, Yahni, Chinese steamed eggs, Tharid, Chicken soup
Collection: Food Ingredients, Soups
Broth is a liquid food preparation, typically consisting of water, in which bones, meat, fish, cereal grains, or vegetables have been simmered.[1] Broth is used as a basis for other edible liquids such as soup, gravy, or sauce. It can be eaten alone or with garnish. If other ingredients are used, such as rice, pearl barley or oats, it is then generally called soup.
Commercially prepared liquid broths are available, typically for chicken broth, beef broth, and vegetable broth. Dehydrated meat stock, in the form of tablets, is called a bouillon cube. Industrially produced bouillon cubes were commercialized by Maggi in 1908 and by Oxo in 1910. Using commercially prepared broths allows cooks to save time in the kitchen.
Refining 1
Cultural distinctions 2
Broth has been made for many years using the animal bones which, traditionally, are boiled in a cooking pot for long periods to extract the flavor and nutrients.[2] The bones may or may not have meat still on them.
Egg whites may be added during simmering when it is necessary to clarify (i.e., purify, or refine a broth for a cleaner presentation). The egg whites will coagulate, trapping sediment and turbidity into a easily strained mass. Not allowing the original preparation to boil will increase the clarity.
Roasted bones will add a rich flavor to the broth but also a dark color.
Cultural distinctions
In Britain, a broth is defined as a soup in which there are solid pieces of meat or fish, along with some vegetables. A broth is usually made with a stock or plain water as its base, with meat or fish added while being brought to a boil, and vegetables added later. Being a thin and watery soup, broth is frequently made more substantial by adding rice, barley or pulses.[3][4]
In East Asia (particularly Japan), a form of kelp called kombu is often used as the basis for broths (called dashi in Japanese).
In the Maldives the tuna broth known as garudiya is a basic food item, but it is not eaten as a soup in the general sense of the term.[5]
Bouillon cube
Scotch broth
Rosół
^ Xavier Romero-Frias, The Maldive Islanders, A Study of the Popular Culture of an Ancient Ocean Kingdom, Barcelona 1999, ISBN 84-7254-801-5
Ice, Oxygen, Hydrogen, Energy, Drinking water
Malé, India, Sri Lanka, Pakistan, Yemen
Water, Salt, Polish cuisine, Russian cuisine, Ukrainian cuisine
Yahni
Greek cuisine, Pakistan, Turkish cuisine, %s%s, Pekmez
Chinese steamed eggs
Chinese language, Pinyin, Cantonese cuisine, Pearl River Delta, Cantonese


(or $185 with food stamp documentation. You must have medical records at the time of the appointment).
(or $75 with food stamp documentation).
(or $155 with food stamp documentation. You must have medical records at the time of the appointment).
(or $455 with food stamp documentation. You must have medical records at the time of the appointment).
(or $275 with food stamp documentation).
(or $405 with food stamp documentation. You must have medical records at the time of the appointment).
your Certification can take place as soon as the next day.
1. Bring them in person.
2. Fax them to 623-321-0219.
3. Use our Contact form to upload your records.
1. Download and fill out our Medical Records Release form and fax to 623-321-0219.
you when your medical records have arrived.
Cupping is used to treat pain, ease scar tissue deep within muscles and connective tissues, and reduce swelling and muscle knots. Also, like many complementary treatments, cupping is used to minimize circulating toxins by drawing them into the skin where they are more easily removed.
Let's do something about those pesky, little imperfections.
(Fill in our Intake form before your first consultation then our Botox form if required).
Botox is a purified Botulinum toxin and is used to soften facial lines and wrinkles. Botox works well for forehead lines, crow's feet and frown lines. Botox is injected into the muscle in these areas and works by weakening the muscle, which in turn lessens the lines of facial expression. Botox relaxes the muscles so they do not contract fully. Botox blocks impulses from the nerve to the tiny facial muscles that are related to expression lines.
BOTOX units per procedure: (may vary per individual patient).
We have CBD tinctures for sale. CBD is famous for the promise it holds for treating treatment-resistant forms of childhood epilepsy. A number of clinical trials, testing the efficacy of CBD in human epilepsy patients, are currently underway. But there is also evidence, mainly from animal studies and in vitro experiments, that CBD may have neuroprotective, anti-inflammatory and analgesic (pain-relieving) properties, and potential therapeutic value in the treatment of motivational disorders like depression, anxiety, and addiction.
What's the biological basis for this wide range of potential medical uses? A key part of the answer lies in CBD's promiscuous pharmacology—its ability to influence a wide range of receptor systems in the brain and body, including not only cannabinoid receptors but a host of others.
All natural, enhancing the body's own elimination processes; Liver, Gall bladder, Pancreas, Stomach, kidneys and skin. A proprietary blend of micronutrients to aid weight loss, enhance energy, and reduce fatigue.
A vitamin injection booster made readily available to cells in the form of methylcobalamin.
(Download and fill in our B-12 Consent form).
Several organic herbs and medicines are available.
Herbs were commonly used before western pharmaceuticals were introduced. Treating and preventing medical conditions with herbs is naturally safe, as an overdose would cause irritation or nausea instead of landing one in the emergency room.
 Are you disabled? Unable to leave your home? Are you in hospice care?
Do you have questions about the Medical Marijuana Program and would like to schedule a private in home session?
Requires SNAP Benefits. To qualify for this State discount you MUST provide, at time of the appointment, a copy of a current eligibility letter or an EBT card with your NAME on it.
A solution of concentrated dextrose and local anesthetic ( no steroids) is injected into the affected ligaments, tendons, or joint capsules. This solution encourages growth of new ligament or tendon fibers to help repair the damaged tissue.
(Download and fill in our Consent form) .
Intravenous micronutrient therapy for treatment of Parkinson's.
and inflammation such as hepatitis and fibrosis.
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Your medical history and your current condition will be evaluated and a treatment plan devised.
our Forms page to fill in the Intake form online or use the link above in the dashboard.
appointments are for 30 minutes.
Traditional Chinese medicine (TCM), therapeutic treatment for a wide range of diseases and conditions including pain syndromes, allergies, depression, lack of energy, cancer, stroke, gynecological disorders and GI problems.
This is a comprehensive physical evaluation to help screen athletes for potential illness or conditions that may limit or restrict their sports activity and help determine their fitness for athletic activity. This evaluation meets the requirements of the Arizona Interscholastic Association for participation.
Download and fill in the AIA Physical Evaluation form.
(Download and fill in our SymptomChart and Informed Consent form).
Individually tailored treatment regimens following consultation.
boost to your immune system. Ideal for patients with immunocompromised systems.
Extra zinc and mega-dose Vitamin C are included.
conditions, chronic vomiting , chronic diarrhea.
Intravenous micronutrient therapy for detoxification. Ideal for detoxifying patients.
IRIE NATURAL MEGA VITAMIN C (orthomolecular protocol) Intravenous micronutrient therapy for treatment of various clinical conditions including cancer, reduces toxicity from chemotherapeutic agents.


Supporters of Uche Nwosu, son-in-law to Rochas Okorocha, governor of Imo state, mounted billboards with his picture and that of President Muhammadu Buhari across Imo on Monday.
Nwosu had lost out in his bid to secure the governorship ticket of the All Progressives Congress (APC) despite efforts of his father-in-law.
The national working committee of the APC had declared Hope Uzodinma, a serving senator, as candidate of the party in the state.
Commenting on this while addressing his supporters in Owerri, the state capital,Okorocha said Nwosu was robbed of the ticket.
He said he would not stop him from joining another party to pursue his governorship ambition.
"What happened in Imo was a clear case of injustice, where Uche Nwosu won the primary and was robbed of the ticket. This injustice must be addressed.
However, in spite of the fact that my aides are leaving the party, I am still a member of APC and will not leave the party," he had said.
Okorocha had absolved Buhari of the alleged irregularity, blaming it on Adams Oshiomhole, national chairman of the APC.
The billboard mounted across the state shows Nwosu is now a member of Action Alliance.


"If you knew me, you'd know that I'd never post pictures of me for the world to see! To some it looks like I've been on an exercise & diet fad, here's the thing … I HAVEN'T.
Mid-July this year I took a step (quite a number actually) … climbed up what seemed like a million stairs to Universal Health and with the help, support and guidance of Nic & Roger made some permanent lifestyle changes … I'm choosing to live with the thoughts of "nourish, move, rest" (rather than diet and rush!).
After 20 weeks I'd lost 20kg (21.5kg as of today). I've gone from a size 20 to a loose 14 and I can RUN 5km and walk 21km!!! (First picture taken April 2014, 2nd yesterday). The weight loss is obviously amazing, but the life I've gained is so much more amazing!! Among other things, thanks to the changes in my diet, I no longer get headaches (except for when I eat too much chocolate), I sleep (before that I was always awake at 330am for the day) and my Heyfever has all but gone! I tried on a dress last night in a shop for the first time in years and one day soon I may even buy one! Sometimes my job is really stressful & I don't manage things particularly well … but I'm learning new ways of dealing with stuff & thanks to the things I've learnt from these guys about nutrition, exercise, rest, cooking … I'm looking forward to lasting the distance in life.
What I like about Nic & Roger is that they are actually living what they teach … and share that information without judgement and with patience (even though I ate a whole lot of chocolate and I thought I'd failed, they still think I'm doing amazing!). I'm still walking along this path and I have another 15kg to lose – the first 20kg took almost no effort at all and I ate more than I ever have …am sure the next 15kg will be ok too.
Roger has been a competing body builder for many years. In the off season Roger has historically gained body fat, and had to work very hard to get the body fat off. He has tried all sorts of approaches, and in 2014 after a year off he chose to do it differently. He chose to practice what we at Soul-full Living preach. His focus was on nourishment, reducing stress, training hard, and using supplementation (natural supplements) and sprints to achieve the goals he had set. He competed in both Nabba and Naturals competitions, and has his sights set now on new goals for 2015.
This is his 2014 transformation.
Dave Hadfield took the 20 Week Challenge and after some hard work saw some amazing results!
Michelle says I don't snore nearly as loud as before I started this journey, so that's a good thing, not sure if it's down to weight lost or just being fitter. I had to get some new work pants, as the current ones were way too big now and I had no more holes left in my belt!! I also brought some new jeans. Towards the end of July now, and I'm down around the 86kg mark!!
I've made some good friends on my journey to a better me, and will always be grateful to them, and especially to Roger, for his support and effort, to get me on the right path. I can't wait until I see the final photos and see what I will have achieved. I plan to continue my healthy path when the 20 weeks is up.


text:
Puma Swede, született Johanna Jussinniemi (Huddinge, Stockholm, 1976. szeptember 13. – ) svédországi finn születésű amerikai pornószínésznő, fotomodell, sztriptíz-táncosnő, Pályájának 2005-ös indulása óta mintegy 108 pornófilmben szerepelt.

Pályafutása
Johanna Jussinniemi a Stockholm elővárosában, Huddingében született svédországi finn családban. Szülei korábban a finnországi Ouluból,  Uleåborg) költöztek ide.

Johanna először Svédországban dolgozott üzletkötőként számítógép-kereskedelmi cégeknél. Később minőségi fotomodellként kapott megbízásokat, majd fejest ugrott a pornográf filmkészítésbe.

2004-ben, 28 évesen Kaliforniába költözött. Összeköltözött Keiran Lee brit pornószínésszel, jelenleg vele él. Szoros barátságot tart fenn Nikki Benz pornószínésznővel is. Ebben az időben vette föl a Puma Swede művésznevet.

Pornószínésznői pályájának kezdetén még csak leszbikus jelenetekben szerepelt, férfiakkal együttesen előadott első hardcore jelenetét csak 2005-ben, az Antiinnocence Video filmstúdió School of Hardcore c. pornófilmjében forgatta. (Johanna ettől a stúdiótól már korábban is kapott szerep-szerződéseket).
2009-ben a pornófilm-készítők díjára, az AVN Award-ra jelölték, mint az év legjobb internetes ifjú pornósztárját (Web Starlet of the Year),
és ugyanebben az évben az XBiz-díjra is jelölték, mint az év Netes ifjú pornósztárját (Web Babe/Starlet of the Year).

Saját honlapján Puma maga írt meg leszbikus és biszex szokásairól, ugyaninnen tudható impozáns testmagassága (178 cm), valamint az, hogy jelenleg (2010 áprilisában) honlaptervezői (webdesign) képzésre jár.

Testi jellemzői
Puma sikerének egyik záloga impozáns kebelmérete, az amerikai tucatmodellekhez képest magas, nyúlánk termete, és skandináv felmenőitől örökölt, érdekesen egyéni arcvonásai. Testi adottságai: testmagassága 178 cm (5 láb és 10''). Testsúlya (2004-ben) 56 kg (123 font), testméretei 81,5–63,5–89 (32F-25-35), szeme kékeszöld, haja szőke.

Díjai
 2009 – AVN Award jelölés
 2009 – XBIZ Awards jelölés (Web Babe/Starlet of the Year)

Fontosabb filmjei
 Diary of a MILF (2006)
 Naughty Office (2006)
 American Daydreams (2006)
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Home Science How an 'atlas' of living organs could save lives
How an 'atlas' of living organs could save lives
Theresa Taboada/Press releases
After an accident, a patient was rushed into surgery and, from there, into the intensive care unit, where he was recovering. But, days later, one by one, his organs failed. The patient didn't survive. Later, trying to understand what went wrong, doctors ordered an autopsy. But the result was a puzzle: the organs weren't damaged. So why did they shut down?
This is a typical story of multiple organ dysfunction syndrome, better known as multiple organ failure. Although it's the leading cause of death in patients who make it through the first few hours after a trauma, its origins remain a mystery.
Plamen Ch. Ivanov, a research professor of physics at Boston University, and his colleagues at the university's Laboratory for Network Physiology think the answer may lie not in the individual organs but in the biological communications network that keeps them working in sync. They are laying the groundwork for an emerging field—network physiology—to study these connections and generate a new human "atlas" that will reveal how organ systems interact in both sick and healthy patients.
Ivanov introduced the field to the scientific community with a 2012 paper in Nature Communications, and he delivered the opening lecture at a Harvard symposium on network medicine later that year. A special issue of the New Journal of Physics followed in 2013. "We were really opening a blank page," Ivanov says.
Organs in isolation
Biologists and doctors have typically studied organs in isolation. If you're having heart trouble, you go to the cardiologist; if your eyes are bothering you, you see an eye doctor. This "reductionist" approach "has been very useful scientifically in every field for the last two to three hundred years, but it has its limitations," especially in biomedicine, where it is impossible to isolate the systems that make up the whole, says Joseph Loscalzo of Harvard Medical School, who studies the related field of network medicine, which aims to understand the relation between diseases and genetic mutations using graphs and networks.
"Maybe we can see something in the coupling between systems that we cannot see in the individual systems"
Loscalzo and Ivanov discovered that they were both interested in developing novel network approaches to medicine and the human body when Ivanov joined Harvard Medical School's Sleep Medicine division.
Treating organs in isolation also can't explain medical crises that seem to happen in the space between individual organs, like multiple organ dysfunction, or altered states like coma.
Yet examining the linkages between the organs is a major challenge. For one thing, there's the problem of time: each organ seems to hear the ticking of a different clock. The eyes and brain exchange lightning-quick signals in a matter of milliseconds; the kidneys plod along through a 24-hour cycle; the heart beats every second or so. Communication between the organs takes multiple forms, too. Electrical signals combine with chemical messengers like hormones to form a sort of internal full-body internet. And, of course, we still don't have a complete understanding of how individual organs work.
Building an 'atlas'
But to figure out how the network functions, Ivanov and his colleagues have to start with even more basic questions, says Ronny Bartsch, formerly a research assistant professor of physics at Boston University and now part of the faculty at Bar-Ilan University in Israel, who has worked with Ivanov since 2008.
"What do we measure?" he asks. "Do we have the technology to measure it? And can we make sense of the measurements?" It isn't as simple as just collecting heart rate or EKG readings, points out Ivanov: the real challenge is getting useful information from these signals.
To address this challenge, Ivanov has assembled a team of scientists, including researchers with backgrounds in statistical and computational physics, neuroscience, physiology, applied mathematics, and biomedical engineering.
The ultimate result of their work, they hope, will be a new way of looking at the human body—what Ivanov calls a dynamic "atlas" animated with the living, changing connections between organs. Ivanov describes the atlas as a collection of "blueprint reference maps" that will ultimately show how the body's systems interact under all sorts of human conditions: healthy and sick, young and old, awake and asleep, stressed and relaxed.
This atlas will be to the traditional, encyclopedia-style atlas of human anatomy what a live traffic report is to a paper road map, revealing not just the "infrastructure" of the body but the traffic that animates it.
A closer look at sleep
Ivanov and his colleagues asked themselves: When is the body most isolated from all the noises, sights, smells, and activity of the world? Answer: During sleep.
Sleep also presented a compelling scientific mystery: How do the body and brain manage to seamlessly transition from one sleep stage to another, over and over again, each night?
Ivanov had previously studied how variations in heart rate change during each stage of sleep. The next step would be to see not just how individual systems operate during sleep, but also to map how the connections between brain and body change as a person passes into light sleep, deep sleep, and REM sleep. For full eight-hour sleep periods, Ivanov and his colleagues tracked subjects' brain activity, eye movement, breathing, heart rate, and leg and chin movement. Then they looked for correlations between activity in each part of the body.
During deep sleep, they found, most of the body's systems seemed to be disconnected. But new linkups suddenly switched on when each subject shifted into REM sleep. Even more connections flipped on for light sleep until, when subjects woke up, all the connections were suddenly illuminated. His team was astonished to find how quickly the communication network could be rearranged, Ivanov recalls.
Though researchers had expected that the body's "network topology"—that is, the shape of a map that represents its connectivity—would change over hours or days, no one had anticipated that it might change in a matter of seconds.
Real-time organ maps?
Sleep, though, is just the first test case in a much broader research program. In 2015, Ivanov's team will bring their work into a real-world laboratory where the stakes are, literally, life-and-death: the Medical Intensive Care Unit at Massachusetts General Hospital, which takes a multidisciplinary approach to caring for severely ill patients.
The goal: a new model of ICU monitoring in which the connections between a patient's body systems are being constantly mapped in real time, so that dangerous breakdowns, like the ones that might cause multiple organ dysfunction, can be anticipated and even prevented.
Today's monitoring devices aren't capable of taking in and integrating all this data from multiple systems, says Ivanov. That's where the device makers at MD PnP come in. Working with MGH's MICU physicians and members of the Network Physiology Lab, they will be designing new all-in-one monitors that record heart rate, respiration, and more.
Making sense of all that data, and discovering which dropped connections should raise alarms, will fall to data scientists like Aijing Lin, who is visiting the Network Physiology Lab from Beijing Jiaotong University in China, and Xiaolin Huang, a biomedical signals expert visiting from Nanjing University. With the right biomedical data in hand, they hope, it may even be possible to flip the "reactive" model of critical care on its head and prevent the events, like heart failure, that send patients to the ICU in the first place.
"It's very difficult to predict sudden cardiovascular events," says Huang. Doctors track patients' blood pressure and heart rate, but by the time blood pressure starts dropping, says Huang, it is too late to stop a heart attack. "Maybe we can see something in the coupling between systems that we cannot see in the individual systems," says Ivanov. That could help doctors predict imminent cardiac events before heart rate and blood pressure change.
Just as it has been a long road from the first human genome to meaningful medical applications, it will take time for network physiology to mature into new diagnostics and treatments. When it does, though, Ivanov hopes that it will reveal a fresh picture not just of illness, but of health, too. "Most biologists have a healthy skepticism about whether this approach will yield new insight. But the evidence that it will is growing," says Loscalzo.
This text is published here under a Creative Commons License.
Author: Kate Becker-Boston University
Check here the article's original source with the exact terms of the license to reproduce it in your own website
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"I would still like to go up in the space shuttle. It's appalling that the accident happened, but it was an accident and obviously if I knew there was any risk, I'd be foolish to do it. I'd love to stand outside the Earth and look at it. Extraordinary feeling that, something that we've been tied to for millions of years, and a handful of people have looked at it, to be able to do that would be stunning."
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text:
Skala Oropou () è una ex comunità della Grecia nella periferia dell'Attica (unità periferica dell'Attica Orientale) con 3.775 abitanti secondo i dati del censimento 2001.

È stata soppressa a seguito della riforma amministrativa, detta Programma Callicrate, in vigore dal gennaio 2011 ed è ora compresa nel comune di Oropos.

Località
La comunità è suddivisa nei seguenti villaggi (popolazione al 2001):

Skala Oropou (pop. 1.289)
Chalkoutsi (pop. 2.082)
Nea Politeia (pop. 404)

Note

Altri progetti

Comuni dell'Attica soppressi


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What on earth is the Kyrangle?
Thank you for asking! When I named the "Star Spangled Kyrangle", I thought it was common knowledge, as it is marked on Google Maps. But it managed to bemuse some local residents who hadn't heard the name before.
It's the area of green next to Clyst Heath School, west of the railway line. In times past, the area used to be a quarry and source of red sand. I wonder whether 'Kyrangle' is a corruption of 'quarry'.
Here is what the area looks like on the old OS map from 1873-88 compared with today.