text:
Children DO appear to have a much lower chance of suffering severe coronavirus cases, CDC research confirms
There have been only three reported coronavirus deaths among U.S. children, even as it kills thousands of older adults
Contradicting some previous hysterical media reports to the contrary, the first major CDC report on how the new coronavirus is impacting children in the United States indicates that they are apparently much less likely to develop severe cases than adults.
However, as The New York Times reports, there have nevertheless been some children who have become very ill from COVID-19, the respiratory illness that coronavirus can cause.
At least three children have died of the disease, according to the CDC report, which was published Monday.
Concerningly, because children seem to have milder overall cases of coronavirus infection, it is possible that young people infected with the virus may drive transmission to others.
(Photo by Yifan Ding/Getty Images)
The most common symptoms among children with the virus, Fox News reports, are fever, cough and shortness of breath -- just as with adults. But children appear to have it better off than adults where such symptoms are concerned.
[The CDC report states] that children appear less likely than adults to develop any of the major known coronavirus symptoms: fever, cough or shortness of breath. That could suggest that many children have mild or undetected cases of the disease and could be spreading the virus to others in their families and communities. "We don't think many kids get severe disease, so are kids transmitting the disease at a significant rate that's going to propagate this outbreak?" asked Dr. Srinivas Murthy, an associate professor of pediatrics at the University of British Columbia, who was not involved in the study. The answer to that question, he said, will be important in deciding how to manage the pandemic, when to reopen schools and how to predict future waves of infection.
U.S. Children With Coronavirus Are Less Hard Hit Than Adults, First Data Shows
As the Washington Post reports, the CDC study looked at the nearly 150,000 confirmed cases of coronavirus reported in the United States between February 12 and April 1.
Just 2,572, or 1.7%, of those reported cases were in children younger than 18.
This does not necessarily suggest that only a small number of children are contracting the virus. Given the inadequate coronavirus testing the U.S. has thus far performed, the diagnosed cases tend to be those that are more symptomatic. Parents may simply not take children in for testing if their symptoms are mild or nonexistent.
So such children's cases may fly under the radar.
For most people, the virus causes mild or moderate symptoms that clear up in a few weeks. But for some, especially adults above 60 and people with existing health problems, it can cause life-threatening illnesses like pneumonia. Confirmed U.S. cases top 356,000 with more than 10,500 reported deaths. Globally, there have been more than 1.3 million confirmed cases, and nearly 74,000 reported deaths.
CDC's first national data showing coronavirus' impact on children
Another major limitation of the CDC's pediatric coronavirus study was the considerable gaps in the available data about pediatric coronavirus cases. For example, for many of the children, the CDC did not have information about whether they were hospitalized.
There were data available on the hospitalization status of 745 of the children with confirmed coronavirus. About one in five of them, or 147, were hospitalized.
(Photo by DOUGLAS MAGNO/AFP via Getty Images)
Again, this figure does not mean that children have a 20 percent chance of hospitalization if they contract the virus, given how the overall sample of diagnosed pediatric cases was biased toward children experiencing symptoms.
By comparison, of the identified adult cases of coronavirus, about one in three involved hospitalization. The overall adult sample is also biased toward cases that are more symptomatic.
The CDC did not provide details about the three children who have died of COVID-19. However, as The New York Times points out, an infant in Illinois has died of the disease, according to the state's health department.
Studies on coronavirus in adults have indicated that those with underlying medical conditions are at greater risk of severe symptoms as well as death. These conditions include diabetes, cardiovascular disease, lung disease, kidney disease, cancer and having a suppressed immune system.
The CDC's data indicated that boys appeared somewhat more likely to be diagnosed with coronavirus than girls, as the Daily Mail reports.
Fifty-five per cent of the 2,500 coronavirus cases in under-18s were boys. Forty-two per cent were girls, while the gender was unknown for another three per cent. The researchers said the higher rate of boys testing positive 'suggests that biologic factors might play a role in any differences in COVID-19 susceptibility by sex'. Females are believed to have a stronger immune system due to genetic differences, making them more resilient to fight off infections like SARS-CoV-2 [the official name of the new coronavirus].
55% of child coronavirus cases are BOYS, reveals CDC report - with up to one in five children who catch the illness needing hospital care
Unfortunately, the CDC study had data on the underlying health conditions of children with confirmed coronavirus in only 13 percent of cases.
Just 10 percent of the children's case reports provided the CDC with information about any symptoms they had as a result of the infection.
Among the 291 children for whom there were data on symptoms, three quarters had a fever, cough or shortness of breath. By comparison, 93 percent of the reported adult cases for which there were data on symptoms experienced such health outcomes.
The CDC said its findings seemed to support an earlier study on pediatric cases in China, which found that covid-19…might be less severe in children. The CDC researchers cautioned, however, that the information was incomplete and that severe cases have been reported among some people younger than 18, including three deaths that remain under investigation.
U.S. children less likely than adults to get very ill from coronavirus, CDC study suggests
Indeed, a previous study of Chinese children found that some 6 percent of 2,150 confirmed or suspected pediatric cases or coronavirus resulted in a severe or critical health outcome. One 14 year-old boy died. Severe illness appeared more common among those who were five years old or younger.
"Social distancing and everyday preventive behaviors remain important for all age groups because patients with less serious illness and those without symptoms likely play an important role in disease transmission," the authors of the CDC report concluded.
'Tiger King' star Joe Exotic is '100 times worse' in real life, videotaped his workers having sex with zoo animals and stored frozen dead tiger cubs: niece


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Q: Using functions from dplyr package to add equation to qqplot with facets I'm trying to produce scatterplots with regression equation and r2 for grouped data.
I can do one, but with grouped data I'm finding trouble when calculating the equations and r2 for all groups in a way that can be automatically extracted and added as annotation.
I believe that I'm pretty close, just making some silly mistake but can't seem to identify it.
1 - First I create a function that creates a model and the string of characters with the results.
library(dplyr)
eqlabels <- function(iris){
  m <- lm(Sepal.Length ~ Sepal.Width, iris);
  eq <- substitute(italic(y) == a + b * italic(x) * "," ~~ italic(r) ^ 2 ~ "=" ~ r2,
                   list(a = format(coef(m)[1], digits = 3),
                        b = format(coef(m)[2], digits = 3),
                        r2 = format(summary(m)$r.squared, digits = 2)))
  as.character(as.expression(eq));
}

I came as far as this, but on step 2 it all breaks down:
2 - Now I must use the function on the grouped data.
This post suggests the use of ddply (from plyr package). I tried to replace that with something equivalent from the dplyr package, as suggested here.
 labelsP3 <- iris %>% group_by(Species) %>% do(eqlabels(.))

However, this results in warning message (and then it does not plot...):
Warning message:

Error: Results are not data frames at positions: 1, 2, 3

As suggested here, I tried:
labelsP3 <- iris %>% group_by(Species) %>% do(with(eqlabels(iris)))

But this results in error:

Error in eval(substitute(expr), data, enclos = parent.frame()) :
    invalid 'envir' argument of type 'character'

The plotting should be fine like this, but I'm stuck at this stage.
plot3 <- ggplot(iris, aes(x = Sepal.Length, y = Sepal.Width)) + geom_point(colour = "grey60") +
  facet_grid(Species ~ .) +
  stat_smooth(method = lm) +
  annotate("text", label = labelsP3, parse = TRUE)

Thank you.

A: Alrighty let's try this again:
do the following:labelsP3<-ddply(iris,.(Species),eqlabels) that will get you your equations:
    Species
    1     setosa  italic(y) == "2.64" + "0.69" * italic(x) * ","
~italic(r)^2 ~ "=" ~ "0.55"
    2 versicolor italic(y) == "3.54" + "0.865" * italic(x) * "," ~
~italic(r)^2 ~ "=" ~ "0.28"
    3  virginica italic(y) == "3.91" + "0.902" * italic(x) * "," ~
~italic(r)^2 ~ "=" ~ "0.21"

Now that you have the equations, you should easily be able to plot them on your graph
you can then use this to graph the equations on your plot
geom_text(data=labels3, aes(label=V1, x=7, y=2), parse=TRUE)

EDIT: THIRD TIME IS A CHARM
So after a lots of trial and error I got it to work, I still get a warning but at least it's a step in the right direction. As I suspected earlier, you have to use as.data.frame, like so:  labelsP3 <- iris %>% group_by(Species) %>% do(as.data.frame(eqlabels(.)))
you get the following output:
     Source: local data frame [3 x 2]
        Groups: Species [3]

             Species                                                                   eqlabels(.)
              (fctr)                                                                         (chr)
        1     setosa  italic(y) == "2.64" + "0.69" * italic(x) * "," ~
~italic(r)^2 ~ "=" ~ "0.55"
        2 versicolor italic(y) == "3.54" + "0.865" * italic(x) * "," ~
~italic(r)^2 ~ "=" ~ "0.28"
        3  virginica italic(y)

    == "3.91" + "0.902" * italic(x) * "," ~ ~italic(r)^2 ~ "=" ~ "0.21"

Does that help you??
UPDATE:
For the plotting part you can do it as follow:
    plot3 <- ggplot(iris, aes(x = Sepal.Length, y = Sepal.Width)) + geom_point(colour = "grey60") +
      facet_grid(Species ~ .) +
      stat_smooth(method = lm) +
      geom_text(data=labelsP3, aes(label=`eqlabels(.)`, x=7, y=2), parse=TRUE)

the x and y is geom_text is for the placement of the label on the graph.
or this even looks a bit better:
 plot3 + geom_text(data=labelsP3, aes(label=`eqlabels(.)`, vjust = -1, +
hjust=-0.5,x=4, y=0), parse=TRUE)

redpajama_set_name: RedPajamaStackExchange


Lucky Lindy we dug you as a flyboy, but what's the deal with all the chicks ?
OK, we can give the nod to Charles Lindbergh as the first flyboy who flew solo from New York to Paris (has Jimmy Stewart ever been finer?), but the whole America First Committee (AFC) thing, where as the chief spokesman, he campaigned to keep the United States out of World War 2 and was branded an anti-semite for statements he made on behalf of that cause (" The Jews are a race with undue influence in the media, warning that the passions and prejudices of such " other people" would lead the country to ruin.") We knew then that there was something dark, twisted, and acheiving a high mark on the weirdo meter, behind his big blues. He was a supporter of racial purity and a staunch eugenicist, which is someone who believes in the improvement of the human species through control of hereditary factors in mating. Lindbergh's knowledge of this came from breeding animals on the farms of Minnesota. More black marks on his resume – he never really retracted his groove of Nazi Germany in the 1930's and made public the invincibilities of the Nazis and their value as a bulwark against the hated Russians, who he regarded as a much greater evil.
Lindy's private life was no day at the beach, most of which was his own doing. He married Anne Morrow, daughter of the U.S. Ambassador to Mexico, and stayed married for 45 years. Towards his own family Lindbergh could be cruel, locking his 18 month old son out of the house to foster independence and forbidding his wife to cry when the baby was famously kidnapped and murdered a few months later. Anne was a very accomplished author and a champion of women's flight but Lindy was " physically and emotionally absent" and was a control freak of the highest degree. Needing someone to tell her she was a groove, Anne entered into an affair with her own physician who provided support and fun – something that Charlie was never good at.
Lindbergh's real weirdness emerged when after he died of cancer, it was revealed that in addition to his five kids he had with Anne, Charlie had not one, not two, but three separate families living in Germany and Switzerland from which he had 7 more kids. All were perfectly concealed until after he was gone. The three lovers bore him 7 kids between the years 1958 and 1967. The children recall a tender father who always arrived in a Volkswagon beetle wearing a beret (was it raspberry in color ?) Their mothers told the children that their father was a famous writer from the United States who had been trusted with a secret mission and they should never speak of him. Their birth certificates declare "father unknown". No wonder that the very popular dance " The Lindy Hop" was named for Charlie.
Then in 1972 , at age 72 , the " Lone Eagle" crashed to earth, dying of lymphatic cancer at his home in Maui, Hawaii. Always the control freak, he specified the exact dimensions and constructions of his grave (" Father was obsessed with drainage" said son Jon.) (Aren't we all?) He wanted his body wrapped in all cotton sheets, but had to settle on a cotton- polyester blend (all they had at the local store – don't you hate that). Only his wife Anne was allowed to sit at his deathbed when" Lucky Lindy " exhaled his last breath and only then by instructions could she kiss him. He hated to be touched.
Charlie Lindbergh was an excellent flyer, but a flawed man who was a cold customer with deep rooted weirdness. Maybe he is guy who could fly you out of a sky full of trouble, but let's not call Charlie for the good times. Groove.
Scott Berg is a wonderful writer. In addition to his book about Lindbergh, he has written biographies of Max Perkins, Samuel Goldwyn, and Kate Hepburn. He is a graduate of Palisades High School, 1967, est.


What jumps out of your mind when you hear the word ballerina? Is it an image of a waif like a-la-Black-Swan's-Nina-Sayers antihero? Probably a woeful, willowy creature, maniacally counting the calories of her sans-dressing cucumber salad, in the very rare moments when she is not toiling away at the barre of shame? What if you found out that inside that twirling head of hers hide demons and insecurities, but also wisdom—lots of wisdom, in the making?
"Ballerinas and danseurs undergo years of hard physical and mental training, enduring intense anxiety about both performance and personal body image. Those who stick with ballet are also those who learn the tools needed to manage negative experiences and perceived failure," says Dr. Patrick Williams, who was a Postdoctoral Scholar in the Department of Psychology at the University of Chicago, and lead researcher of a cutting-edge recent research titled: "The Relationship between Mental and Somatic Practices and Wisdom".
Williams and the rest of the team first framed wisdom as: "A deep and accurate perception of reality, in which insight into human nature and a diminished self-centeredness are acquired through life experience and practice in perspective taking," and then sought to track how it develops along some structured mental and somatic practices. They had 298 practitioners of four different physical practices answer a psychological questionnaire inquiring into the amounts of empathy, compassion, self-transcendence and anxiety they possessed—characteristics designated as the building blocks of wisdom. The scientists eventually found ballet dancers to be less wise than, for instance, meditators, but also found prolonged ballet experience to be positively associated with wisdom.
"Wisdom is one of the oldest subjects studied by human-kind as an intellectual pursuit, but as a scientific pursuit, it is one of the youngest. The relationship between ballet and wisdom, in specific, is a mystery to us," confesses the researcher of the pioneering realm of Embodied Cognition. "We can hypothesize, however, that the successful management of pain and resilience to adversity that are part and parcel of a ballet dancer's life might forge paths to wisdom." Continnect drew on this research and chronicled the experiences of three dancers of different level and ability; has dance really made them wiser—how, and why?
Helena Sgouramani already knew at three years of age that she would be a dancer. At six she started practicing daily, and at eighteen she joined Niki Kontaxaki Dance School (and later the Greek National Opera Dance School). In her second professional year, she auditioned in front of the director of the famous Ecole-Atelier Rudra Maurice Bejart Ballet School, Michel Gascard. With a resounding yes, she packed her suitcases and headed for Lausanne, Switzerland.
"At a sensitive age (nineteen), I was in a foreign country alone, pursuing a wild dream. Where others still played, I worked full-time." In due time, the number of dancers that entered the professional arena ahead of their peers started dwindling like a hourglass sand. "Out of the forty dancers that got accepted in my year, eight graduated. Every three months we had assessments. Several were kicked out, others dropped out of their own accord," says the dancer.
Sgouramani, standing erect, spindly, with a balletic body pliability that gives the illusion of bonelessness, was one of the lucky dancers, physically well-suited for the demands of classical dance. Few are the injuries under her balletic belt. "Of course I miss my toenails, and my joints are those of a fifty-year-old, not a thirty-three-year-old woman," the dancer says in jest. "But these are nothing compared to what other dancers have gone through," she adds, flashing on memories of dancers rushed to hospital suffering with life-threatening anorexias, which would usually kick off after someone pointed at those two "extra" kilos.
"I don't recall a single day of my life not dancing," are the words of Pat Catterson, acclaimed choreographer, dancer and veteran teacher, who has choreographed and presented over one hundred works in New York City since 1968, and taught composition and mentored student works at UCLA, the Juilliard School, Danshögskolan in Stockholm and elsewhere. An offspring of parents-ballroom dancers and a tap dancer-grandfather, she had no other choice than first-dance at three.
Still, growing up in Indiana, US, Catterson wasn't given the chance to attend a great ballet school, so she trained, but not at the intensity wannabe ballerinas do. She was, however, a bright student, and later majored in Psychology at Northwestern University. There, her fire for dance re-ignited. She apprenticed with Judith Scott Dance Company in Chicago, participated in the American Dance Festival at Connecticut College, experimented with choreography, and received prizes and accolades. Dance won out. In 1968 she moved to New York, to work under mammoth names like James Cunningham and Yvonne Rainer.
She is now seventy and goes to class every single day. "It is not so much my perfect body that led to my lasting career, but my talent and passion. You can't be mediocre if you are a professional dancer. A plumber can be mediocre and make a living, a dancer no," says the seasoned creator, who often tours the world teaching seminars. "Competition is fierce, and resources are few. To just scrape a living, you quickly figure out that time is money. One moment you learn new steps, the next you throw them away. Let alone the need for constant adjustment. Dance equips you with a mental sharpness, toughness, flexibility and speed," monologues a sleek, spark-eyed, astonishingly fit Catterson, who reminisces the times she adjusted her dancing to a wrecked stage, or out of tune violins. But, if, mentally, dance postulates a hyper-versatility that extends from strict discipline to lines and techniques to ample resourcefulness in unforeseen occasions, what holds true in the case of wisdom?
When Others Count Sheep to Fall Asleep, I Count Ballet Steps. And Everything Falls into Place.
Those who climb the higher echelons of Terpsichore's art might open the gates of wisdom, science says. But, what happens with those who take up ballet as a mere recreational activity? The same groundbreaking research contains surveys showing that even an expanding posture will increase feelings of power and tolerance of risk, while tilting the head upward induces pride. To the extent that somatic training alters movement patterns, Embodied Cognition claims ballet may contribute to psychological changes associated with wisdom. "If you ask me, the upright posture I gained through ballet—something I physically lacked—has certainly boosted my self-esteem," answers forty-four-year-old Leda Contogiannopoulou, one of the leading artists of her generation, albeit in … painting. "The truth is I wanted to become a ballerina, but I liked food a bit too much. At fourteen I came to grips with the fact that my chunky body frame would mean I would literally need to starve to become a ballerina, so I chilled out end enjoyed," the mother of two says.
Stav Dimitropoulos is a journalist and writer who has appeared on CBC, CBS Radio and FOX Channel, and has written for In The Fray, YourTango, Gadgette and many more.


Some commercial applications of assistant capabilities are interesting to see. Some interesting details here.
ATLANTA – Honeywell (NYSE: HON), a global leader in connected buildings, announced the launch of its next generation thermostat for the hospitality industry. Honeywell's INNCOM e7 Thermostat (e7) is the first enterprise grade environmental control and energy management solution that incorporates Amazon Alexa voice control for an effortless guest experience that includes room temperature, lighting, drapery and amenities services. With its modern design with easy-to-use controls, the e7 is based on a patent-pending Smart Wall Plate design that provides hotel staff with an easy and reliable back-up of the device configuration. This makes routine maintenance or replacement of the e7 energy management system simple, even for other staff which helps reduce ownership costs.
The e7 automatically reduces energy costs and is compatible with most HVAC solutions and equipped for Honeywell's Connected Guest integration. Now available for installation, the e7 can maximize guest comfort, energy savings, and operational efficiency. Honeywell's INNCOM hospitality solutions are used in more than 1.5 million guestrooms around the world. .... "


As the war in Syria grinds into its seventh year this week, a vital building block of the country's future has fallen victim to the carnage: the education of its children.
About 1.75 million children and youth in Syria are out of school and most are up to six years behind in their reading and math skills, according to a report published Monday by the International Rescue Committee.
"This is quite alarming," said Paul Frisoli, the organization's senior technical adviser for education. "In a country that really promoted the value of education we are now seeing severely low levels of literacy and numeracy, which can have a severe impact on children's learning going forward."
The aid group did not have access to baseline findings about learning levels in Syria before the war, but the Arab nation was known to have "a 95%-plus literacy rate," Frisoli said.
Access to education and learning are not only problems for children inside Syria, according to advocacy groups. Human Rights Watch reported in September that more than half of the 1.5 million school-age children from Syria taking refuge in Turkey, Jordan and Lebanon were not enrolled in formal education the previous school year.
Without an education, the children are likely to be exploited, get caught in poverty, fall victim to extremist ideologies, and will become a "lost generation," the Karam Foundation, a Chicago-based nonprofit that invests in Syrian schools and supports refugee families, said in a report last year.
Before the war, there were more than 22,000 schools operating across the country, according to the U.N.'s 2017 Humanitarian Needs Overview. Today, at least 7,400 schools are closed and those that remain operational generally have, "poor water, sanitation and hygiene conditions," IRC officials said.
Monday's report, conducted in November and based on a survey of about 3,000 children at five schools in northern Syria, shows that almost half of the 13-year-olds surveyed could not complete a math task designed for 7-year-olds, according to the report. And roughly one-third of eighth graders could not properly read a 60-word story intended for second-graders.
The decline in learning is due to several factors, including interrupted schooling due to bomb threats, violence, insecure access to schools, and disruption of the home environment and family structure, child advocacy officials said.
"We know from neuroscience that children who do experience prolonged toxic stress in their lives, that does hamper their brain development," Frisoli said. "We think there has been learning reversal in some cases. Kids are so stressed because of the environment they are living in."
More than a quarter of the 3,500 schoolchildren receiving assistance from the International Rescue Committee have had to flee their homes, and many were traumatized after witnessing the impact of the fighting on family members and the harm and destruction caused by airstrikes, according to the report.
Other significant findings include the fact that there are 5.8 million children between the ages of 5 and 17 who need education assistance, meaning they have trouble getting to school because of danger along the way, are not learning due to poor quality education or a lack of teachers, and are at extreme risk of dropping out, among other factors. Fifty-nine percent of sixth graders could not read a simple 7- to 10-sentence story--the equivalent of second-grade reading skills--while 63% of seventh graders could not solve a second-grade subtraction problem. Some 150,000 teachers have left the education system.
The Rescue Committee's recommendations for improving learning include studying educational programs that work and determining how best to spend money on schools. The report also calls for putting an emphasis on remedial programs that help reinforce children's basic skills and close the gap between what they know and what they should know at certain grade levels, and helping children build social and emotional skills.


The minister, who made the call when he received the National Association of Nigerian Students, NANS, FCT Chapter, on an advocacy visit to his office last week said the administration has already laid a solid foundation that will take education out of the woods.
He said the impending emergency declaration in the sector will give further impetus to the gains already made.
Bello noted that it was imperative for students to give their support to government to ensure that the agenda is not derailed, adding that students were part of the main group that would benefit when these programmes and policies are eventually realized.
According to him, "We will continue to count on your support because at the end of the day, what the President is doing is building a foundation for a better tomorrow and those that will benefit in this greater tomorrow are basically yourselves and your membership.
"So, we need the primary support of all of you who are the primary stakeholders so that we can build something that as time goes by, all of us will be proud to be associated with."
Speaking earlier, chairman of the association, Comrade Mojeed Omolaja, commended the minister for the giant strides recorded in the FCT education especially achievements at the Federal University of Science and Technology, Abaji.
Omolaja, who announced that members of the association would be embarking on a 5-day rally in the FCT, pledged their willingness to collaborate with the FCT Administration in order to promote the interest and welfare of students.
Highlight of the meeting was the conferment of the award of 'Grand Patron of Nigerian Students in the FCT' on the FCT Minister by the aassociation, in recognition of the positive roles he has played in transforming the education sector in the territory.


text:
The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians
Seon Young Kim, Kwantae Kim, Byungjin Hwang, Kyongok Im, Si Nae Park, Jung Ah Kim, Sang Mee Hwang, Duhee Bang, Dong Soon Lee
Mutational profiles of 153 Korean myelodysplastic syndrome (MDS) patients were investigated. Sequencing of 87 genes presented similar mutational profiles in Korean MDS patients compared with previous reports. The most frequently mutated genes were ASXL1 (22.9%), U2AF1 (16.3%), TP53 (13.7%), RUNX1 (10.5%), TET2 (10.5%), DNMT3A (8.5%), and SRSF2 (8.5%). The U2AF1 mutation frequency was higher, with different frequencies in the mutated sites of U2AF1 (S34Y, 6/25; S34F, 11/25; and Q157P 8/25). The U2AF1 S34Y mutation was strongly associated with isolated trisomy 8 (5/6, 83%) and was characterized by a younger age of MDS onset (median, 39 years). The S34F mutation was associated with trisomy 8 (6/11, 55%) and del(20q) (3/11, 27%). Data from 10 literatures (total 3460 patients) of 229 U2AF1-mutated cases revealed a significant association between the S34Y and trisomy 8 in Asians (P = 0.0001), but not in Caucasians (P = 0.080). We infer that U2AF1 S34 mutations characterize a distinct subgroup of MDS: younger age of onset and differential associations with particular cytogenetic aberrations depending on specific mutations [S34Y to +8; S34F to +8 and del(20q)]. The impact and causal relationship between U2AF1 S34 and trisomy 8 need to be elucidated, which might contribute to design of tailored treatments.
Leukemia Research
https://doi.org/10.1016/j.leukres.2017.09.001
Mutation Rate
Age of Onset
Trisomy Chromosome 8
Kim, S. Y., Kim, K., Hwang, B., Im, K., Park, S. N., Kim, J. A., ... Lee, D. S. (2017). The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians. Leukemia Research, 61, 96-103. https://doi.org/10.1016/j.leukres.2017.09.001
Kim, Seon Young ; Kim, Kwantae ; Hwang, Byungjin ; Im, Kyongok ; Park, Si Nae ; Kim, Jung Ah ; Hwang, Sang Mee ; Bang, Duhee ; Lee, Dong Soon. / The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians. In: Leukemia Research. 2017 ; Vol. 61. pp. 96-103.
@article{53197b7d8a194704922840f54af0d173,
title = "The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians",
abstract = "Mutational profiles of 153 Korean myelodysplastic syndrome (MDS) patients were investigated. Sequencing of 87 genes presented similar mutational profiles in Korean MDS patients compared with previous reports. The most frequently mutated genes were ASXL1 (22.9{\%}), U2AF1 (16.3{\%}), TP53 (13.7{\%}), RUNX1 (10.5{\%}), TET2 (10.5{\%}), DNMT3A (8.5{\%}), and SRSF2 (8.5{\%}). The U2AF1 mutation frequency was higher, with different frequencies in the mutated sites of U2AF1 (S34Y, 6/25; S34F, 11/25; and Q157P 8/25). The U2AF1 S34Y mutation was strongly associated with isolated trisomy 8 (5/6, 83{\%}) and was characterized by a younger age of MDS onset (median, 39 years). The S34F mutation was associated with trisomy 8 (6/11, 55{\%}) and del(20q) (3/11, 27{\%}). Data from 10 literatures (total 3460 patients) of 229 U2AF1-mutated cases revealed a significant association between the S34Y and trisomy 8 in Asians (P = 0.0001), but not in Caucasians (P = 0.080). We infer that U2AF1 S34 mutations characterize a distinct subgroup of MDS: younger age of onset and differential associations with particular cytogenetic aberrations depending on specific mutations [S34Y to +8; S34F to +8 and del(20q)]. The impact and causal relationship between U2AF1 S34 and trisomy 8 need to be elucidated, which might contribute to design of tailored treatments.",
author = "Kim, {Seon Young} and Kwantae Kim and Byungjin Hwang and Kyongok Im and Park, {Si Nae} and Kim, {Jung Ah} and Hwang, {Sang Mee} and Duhee Bang and Lee, {Dong Soon}",
doi = "10.1016/j.leukres.2017.09.001",
journal = "Leukemia Research",
Kim, SY, Kim, K, Hwang, B, Im, K, Park, SN, Kim, JA, Hwang, SM, Bang, D & Lee, DS 2017, 'The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians', Leukemia Research, vol. 61, pp. 96-103. https://doi.org/10.1016/j.leukres.2017.09.001
The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians. / Kim, Seon Young; Kim, Kwantae; Hwang, Byungjin; Im, Kyongok; Park, Si Nae; Kim, Jung Ah; Hwang, Sang Mee; Bang, Duhee; Lee, Dong Soon.
In: Leukemia Research, Vol. 61, 10.2017, p. 96-103.
T1 - The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians
AU - Kim, Seon Young
AU - Kim, Kwantae
AU - Hwang, Byungjin
AU - Im, Kyongok
AU - Park, Si Nae
AU - Kim, Jung Ah
AU - Hwang, Sang Mee
AU - Bang, Duhee
AU - Lee, Dong Soon
N2 - Mutational profiles of 153 Korean myelodysplastic syndrome (MDS) patients were investigated. Sequencing of 87 genes presented similar mutational profiles in Korean MDS patients compared with previous reports. The most frequently mutated genes were ASXL1 (22.9%), U2AF1 (16.3%), TP53 (13.7%), RUNX1 (10.5%), TET2 (10.5%), DNMT3A (8.5%), and SRSF2 (8.5%). The U2AF1 mutation frequency was higher, with different frequencies in the mutated sites of U2AF1 (S34Y, 6/25; S34F, 11/25; and Q157P 8/25). The U2AF1 S34Y mutation was strongly associated with isolated trisomy 8 (5/6, 83%) and was characterized by a younger age of MDS onset (median, 39 years). The S34F mutation was associated with trisomy 8 (6/11, 55%) and del(20q) (3/11, 27%). Data from 10 literatures (total 3460 patients) of 229 U2AF1-mutated cases revealed a significant association between the S34Y and trisomy 8 in Asians (P = 0.0001), but not in Caucasians (P = 0.080). We infer that U2AF1 S34 mutations characterize a distinct subgroup of MDS: younger age of onset and differential associations with particular cytogenetic aberrations depending on specific mutations [S34Y to +8; S34F to +8 and del(20q)]. The impact and causal relationship between U2AF1 S34 and trisomy 8 need to be elucidated, which might contribute to design of tailored treatments.
AB - Mutational profiles of 153 Korean myelodysplastic syndrome (MDS) patients were investigated. Sequencing of 87 genes presented similar mutational profiles in Korean MDS patients compared with previous reports. The most frequently mutated genes were ASXL1 (22.9%), U2AF1 (16.3%), TP53 (13.7%), RUNX1 (10.5%), TET2 (10.5%), DNMT3A (8.5%), and SRSF2 (8.5%). The U2AF1 mutation frequency was higher, with different frequencies in the mutated sites of U2AF1 (S34Y, 6/25; S34F, 11/25; and Q157P 8/25). The U2AF1 S34Y mutation was strongly associated with isolated trisomy 8 (5/6, 83%) and was characterized by a younger age of MDS onset (median, 39 years). The S34F mutation was associated with trisomy 8 (6/11, 55%) and del(20q) (3/11, 27%). Data from 10 literatures (total 3460 patients) of 229 U2AF1-mutated cases revealed a significant association between the S34Y and trisomy 8 in Asians (P = 0.0001), but not in Caucasians (P = 0.080). We infer that U2AF1 S34 mutations characterize a distinct subgroup of MDS: younger age of onset and differential associations with particular cytogenetic aberrations depending on specific mutations [S34Y to +8; S34F to +8 and del(20q)]. The impact and causal relationship between U2AF1 S34 and trisomy 8 need to be elucidated, which might contribute to design of tailored treatments.
U2 - 10.1016/j.leukres.2017.09.001
DO - 10.1016/j.leukres.2017.09.001
JO - Leukemia Research
JF - Leukemia Research
Kim SY, Kim K, Hwang B, Im K, Park SN, Kim JA et al. The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians. Leukemia Research. 2017 Oct;61:96-103. https://doi.org/10.1016/j.leukres.2017.09.001
10.1016/j.leukres.2017.09.001

redpajama_set_name: RedPajamaCommonCrawl


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Damascus residents in defiance of US-led attack rally in support of the Syrian armed forces
SyriaHeadline NewsMENA
By Paul Antonopoulos	 On Apr 16, 2018
DAMASCUS, Syria – Residents of Damascus held a rally at the capital's Umayyad Square, Monday, to show their support for the Syrian military in the wake of the US-led airstrikes on Syrian government targets.
Attendees waved Syrian flags as they chanted in support of the government forces and Syrian President Bashar Assad.
The US, UK and France launched airstrikes against multiple government targets in Syria early on Saturday morning, targeting alleged chemical weapons sites.
A total of 103 cruise missiles were launched during the attack, the Russian Defence Ministry says. At least 71 of those were intercepted by Syrian air defence forces, it adds.
The airstrikes were carried out in response to an alleged chemical weapons attack in the Syrian town of Douma last week. Several Western powers, led by the United States, claimed chemical substances, most likely chlorine and sarin, were used by Syrian government forces on April 7. The claim has been denied by Damascus and Moscow.
DamascusSyria
Former Pink Floyd frontman denounces the White Helmets, calls them a terrorist front – VIDEO
Erdogan does nothing but appease EU on Syria stance


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The creed of the sports columnist
February 16, 2005 12:00 am by Mark Lennox
Lately in the sports world, it seems fitting that the only way to get press is to call your cohorts out. With the release of Jose Canseco's new book, Juiced, the cool thing to do is exploit former friends and future enemies.
Let's give that a shot.
Since the beginning of the spring semester, the sports page has gone through some heavy revamping.
The layout has improved, fit with new bright and shiny pictures for students and Ralph Wiggums alike. There is aimless trivia that floats around the bottom of the section, enticing the reader to turn the page. And finally there has been an influx in the amount of columns run on our beloved sports page.
Now, being a former sports writer who has migrated to the news staff, I find it only fair for current and future sports writers to get a heads-up on the creed of the sports column. We could have called it, "Everything you wanted to know about writing a college sports column but were afraid to ask," but we don't want Woody Allen suing us for title rights.
In that case, we'll go with the simple "College Sports Columns: Where clichés live and breath."
Ok, let's begin.
Step one: Getting past the editor.
You can't just submit a column and expect it to run. First you have to butter up the boss. This may seem to be a daunting task at first, given our red card-carrying captain Sports Editor Mike Camunas. Once you get past his rhetoric and conspiracy theories, compliment him on his smirk and the press pass that constantly dangles from his sleeve. After this, you should be ready to write.
Step two: It is important to make fun of your institution's sports program as much as possible.
Let me stress this point. You can support your team, but having an overall sense of angst is the only way to navigate a sports column. Sports columnists in the rah-rah business, visit TheBullsPen.com.
It doesn't matter if your women's basketball team breaks the school record for wins in a season — if one of them stubs a toe, you had better call her out for it.
If your football team wins by 21, then you say they should have won by 22. Go for a two-point conversion next time, jerks!
Step three: If you ever get into a bind and can't think of what to say, just fill space with a quote from a cheesy '80s flick.
Examples of this would be: "Why did it have to be snakes?" "Let's see if this baby can do 90!" or "E.T. loves Elliot!"
Step four: If all else fails, crack jokes at things that have nothing to do with sports.
Nobody likes the Olsen twins, so why not take pot shots at them? For examples of this, look no further than the trusty UCF Future. The columns seem riddled with schlock regarding the sports editor's lack of a love life and his affinity for said twins. On four occasions in the past two years, the sports editor has used the twins, so I guess this works.
Give the Future's archives a search for the Olsens if you need help placing them in your story. They have been printing for some time without complaint.
Step five: The final step in the process of becoming an elite sports columnist: Burn as many bridges as humanly possible.
This seems to work for Major League Baseball, so why not the rest of sports? Granted, steroids are not rife within The Oracle, but nobody can prove Canseco's claims.
If you really feel the need for a good column and can't come up with anything else, then just fabricate drug claims against your former employers and employees.
With all this information, you should be able to write a funny, outgoing column with no aim or basis. Now that I have revealed the secrets of "the game," I'm sure 60 Minutes will come calling as well as every other media outlet that has bitten on Canseco's claim.
I'm just trying to get my fifteen minutes.
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Thank You Network(SM) Advances Rewards Programs to Another Level
First Reward Program to Include Contemporary Art from One of America's Preeminent Pop Icons, As Part of its Rewards Collection
NEW YORK, NY (May 16, 2007) – In an effort to continuously bring its members the most unique and compelling reward offerings available, ThankYou Rewards Network today announces the beginning of a special relationship with world-renowned artist Peter Max. As the first artist associated with ThankYou Network, Peter Max makes his popular artwork accessible to all 11 million ThankYou Members, including limited edition lithographs.
"I am very pleased to make my artwork accessible to people who previously weren't able to purchase one of my pieces," states Peter Max. "Now through ThankYou Network, members will have the chance to redeem their points for some of my most popular work."
With paintings on exhibition in hundreds of museums and galleries worldwide, Peter Max and his vibrant colors have become a significant part of contemporary culture. Peter Max has been referred to as a Pop icon, Neo Fauvist, Abstract Expressionist and America's "Painter Laureate" – having painted for the last six U.S. Presidents. In addition to his work on canvas, Peter Max's most recent visions have been seen on a Boeing 777 Continental Airlines jet, across a 600-foot stage for Woodstock Music Festival, on the covers of the Verizon New York City yellow and white pages, and on a giant mural unveiled at the 2002 Winter Olympics. He has been designated Official Artist of five Super Bowls, six Grammy Awards, World Cup USA, The World Series, The United Nations Earth Summit, and numerous other events.
"We are so excited to have the art of Peter Max – who is not only a critically-acclaimed artist, but also someone who has enjoyed broad popular appeal throughout his storied and prolific career – as part of the ThankYou Network rewards collection," said Nancy Gordon, Executive Vice President, ThankYou Network. "This relationship follows through on our long-standing commitment to our members to continually provide them with exciting and unique reward opportunities that can be appreciated and valued for a lifetime. Now our members can use their ThankYou Points to become art collectors. From Peter Max posters, limited-edition prints or custom portraits, there is a reward option for everyone."
As a result of ThankYou Network's relationship with Peter Max, members can now redeem points, starting at the 32,200 point level, for fine art to begin or expand their own collection. Members can browse the Peter Max collection on the online gallery at www.ThankYou.com which features a range of 18 pieces spanning the past four decades and includes:
# 2 original works painted in acrylic on canvas
# 10 signed lithograph prints
# 6 posters signed and dedicated to the recipient by Peter Max
In addition, members with high point levels can take advantage of an exceptional and very limited premium reward opportunity – where they can redeem their ThankYou Points to have Peter Max paint a custom portrait of their dreams.
ThankYou Network's relationship with Peter Max was facilitated by The Erlick Group, a New York-based agency that represents leading cultural and entertainment properties.
Citi, the leading global financial services company, has some 200 million customer accounts and does business in more than 100 countries, providing consumers, corporations, governments and institutions with a broad range of financial products and services, including consumer banking and credit, corporate and investment banking, securities brokerage, and wealth management. Major brand names under Citi's trademark red arc include Citibank, CitiFinancial, Primerica, Citi Smith Barney and Banamex. Additional information may be found at www.citigroup.com or www.citi.comg.
ThankYou Network
Founded by Citi, the ThankYou Network is a free rewards program that lets members earn points from a growing network of places and pool these points into one ThankYou Member Account. Members get points for using participating Citi credit cards, banking at Citibank with an eligible checking account and booking qualified travel on Expedia.com. Members can reward themselves with almost anything – from travel, brand-name goods, and gift cards at favorite stores, to unique experiences and charitable donations at www.ThankYou.com
CITIGROUP INC


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Desert DigestQ&A
Chef Lee Hillson Returns to T. Cook's at Royal Palms Resort
Marilyn HawkesDecember 9, 2019
Chef Lee Hillson recently returned to T. Cooks at Royal Palms Resort and Spa as executive chef and he couldn't be happier. He spent 12 years at the iconic resort in the early 2000s as executive sous chef and then as executive chef. Hillson, a James Beard House featured chef and a participant on the Food Network's Iron Chef America, has also graced the kitchens of The Phoenician Resort and the Sheraton Grand at Wild Horse Pass. We caught up with the jovial chef recently to see how things are going since his return.
Why did you decide to come back?
I'm just super excited to be back because I love the Royal Palms. It's like home. To me it's one of the most beautiful places in the Valley, if not in the world. It's gorgeous and my heart is here and I think so many people who work here feel the same. It's just a great opportunity to come home. We have a phenomenal team here.
How have you revised the menu?
We've taken it back to a Mediterranean feel. I brought some old classics back – the lobster bisque, pasta carbonara and paella, although it's coming from the kitchen and not being fired in the fireplace. It's still very good and has a great flavor. I'm just bringing back some of the old flavor profiles and making it more comfort style. I think the menu is more approachable now.
What about Sunday brunch?
You can have the brunch buffet, which has charcuterie and shellfish platters and breakfast items like scrambled eggs, bacon, sausage, potatoes. We also have smoked fish and desserts and different types of salads and you can choose from five or six different entrees, anything from Mary's chicken breast to braised short ribs to the breakfast burger that one of my sous chefs came up with. It's a burger with bacon, hollandaise sauce and egg. It's to die for. We also have peanut banana French toast with bacon mascarpone and crème anglaise. It's off the charts good.
What do you have planned for the future?
I want to get the fireplace back up and running because that was always such an amazing focal point in the restaurant. And then sometime next year, not sure yet when, we'll have lunch cooking classes and demos. The guests will come in – anywhere from 2-10 people – and I or one of the sous chefs will make a three-course lunch in front of them. It will be interactive.
Who inspires you in the culinary world?
My mother. I remember just being in the kitchen cooking with her when I was a kid and I loved watching my parents cooking. It was something that I'd always wanted to do. Whenever I eat certain things, it brings back memories and really that's what we're trying to do in the restaurant. It's just really about invoking memories and taking people back to a happy place.
Lee Hillson
Royal Palms Resort & Spa
T. Cook's
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Scenes of Vermont Forums • Full Harvest Moon 2017- Will you be in VT to watch it rise over the mountains?
Full Harvest Moon 2017- Will you be in VT to watch it rise over the mountains?
Those who know me, know I LOVE full moons. Especially the full harvest moon! Let's hope the weather is clear on the night of the full harvest moon this year. Technically, the Harvest Moon is the Full Moon closest to the September equinox around September 22. Most years it is in September, but around every three years, it is in October. The Harvest Moon is the only Full Moon name which is determined by the equinox rather than a month. Traditionally, people in the Northern Hemisphere spent the month of October preparing for the coming winter by hunting, slaughtering and preserving meats for use as food. This led to October's Full Moon being called the Hunter's Moon, Dying Grass Moon, and Blood Moon or Sanguine Moon. However, this should not be confused with a Total Lunar Eclipse – Blood Moon.
I love it when the harvest moon occurs when I am in Vermont. It is a special treat to be at my inn and see the harvest moon rise over the mountains, stirs the soul! I'll be in Waitsfield this year for this event and am hoping for a clear, autumn evening!
Neil Young's Harvest Moon is the best song to play as the moon rises in Vermont.
Re: Full Harvest Moon 2017- Will you be in VT to watch it rise over the mountains?
Folks! Don't forget the Full Harvest Moonrise in Vermont on October 5th!!! I'm going to sit on my porch at the inn and watch it rise over Common Road in Waitsfield. It's a totally special experience to see it when you are on vacation in Vermont.
The weather is going to be amazing, enjoy!
Peacham is a great place to photograph the moonrise as well. The view to the east is excellent there.
Tim that is one spectacular photo. We will be in Vermont for the full Harvest moon. I can't wait. How far is Waitsfield from White River Junction?
courtmel wrote: Tim that is one spectacular photo. We will be in Vermont for the full Harvest moon. I can't wait. How far is Waitsfield from White River Junction?
If you take I-89 to Middlesex and down Rt 100 it is around 1 hr 15 min.
If you take Exit 3 off of I-89 oyu have the option of going over Roxbury Gap or going over Bethel Mtn Rd to Route 100. Both of which are scenic and will take closer to 1.5 hrs.
The full moon is on October 5th. Note that on 10/5 the moon rises at 6:44 pm and sunset is 6:23 pm.
But on October 4th the nearly full moon rises at 6:13 pm and sunset is 6:24 pm. That night would also be good for viewing and photographing the moon with a little more light available.
Thanks for the information Ed. Two great nights to relax by the harvest moon! It is so enchanting!
Last year I drove up to Common Road to watch the moonrise but it was sooooo dark up there and I started hearing noises in the woods so I scooted back to my inn! I'll watch it from the porch this time. Someone later told me there were porcupines on the same area I was standing!!!
Tim Thanks for the info. I hope Peacham isn't as far from our base in White River Junction. I would love to be around Peacham for the full Harvest Moon on Thursday evening. Your picture is so awesome. Great work! I love this forum.
Oh my goodness! The full harvest moon rising over Common Road was AMAZING tonight! A gorgeous evening in Vermont paired with the full harvest moon. Now how's that for perfection? Sitting on the rocking chairs with a slight breeze curling around the inn and crickets in the background. I'll save this one in my memory bank!
Got some folks at the inn together on the front porch and it was wonderful! Met some incredible travelers here this time around.
Hope you all enjoyed it as well!
Another full moon winner out there tonight! Clear skies and blissful! Hope you all enjoyed watching it rise high in the sky! Most of all, we are here in Vermont to witness such a lovely event!


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Claude Charles François Leblanc de Marnaval est un maître de forges né en 1720 et mort le . Il a fait construire le château de Bouges à Bouges-le-Château.

Biographie
La famille Leblanc est originaire de Saint-Dizier dans la Haute-Marne et possédait au  la terre et les forges du Buisson ainsi que le fief du Châtelier comprenant un haut fourneau. André Leblanc est assesseur en l'élection de Vitry-le-François et achète une charge de secrétaire du roi, dite vulgairement « savonnette à vilain », qui confère la noblesse héréditaire à ses descendants.

Son fils, Claude Leblanc, désigné comme « écuyer », est propriétaire des forges et hauts fourneaux de Marnaval. Le , il quitte la Champagne pour le Berry avec ses quatre enfants :
 Claude Marie François, dit Leblanc de Coings ;
 Marie Angélique qui épousa Louis Girard de Vasson, chevalier de l'ordre royal et militaire de Saint-Louis, dont postérité ;
 André, dit Leblanc de Logny, capitaine des chasses du duché de Berry ;
 Claude Charles François, dit Leblanc de Marnaval.

En 1735, il prend à bail l'exploitation des forges de Clavières (Indre) en formant une société avec de proches parents. Le bail est renouvelé en 1744 puis repris par son fils Leblanc de Marnaval en 1753. Les forges, dont l'activité est soutenue grâce à des marchés passés avec la Compagnie des Indes, lui permettent d'accumuler une grande fortune. Le bail de la forges est porté à dix-huit ans par le Conseil du Roi en 1771.

Son aisance est encore accrue par les revenus de la manufacture royale de draps installée dans le château du Parc à Châteauroux et qui produit du drap de laine destiné à l'habillement des armées. Créée en 1751 à l'instigation de Trudaine, intendant des finances, grâce à un privilège accordé par Louis XV à un tisserand originaire de Lodève, elle est dirigée par Leblanc de Marnaval de 1766 à 1774. Celui-ci dispose d'un correspondant à Paris, Joseph Joachim Méry.

En 1753, Leblanc de Marnaval a fait une alliance brillante en épousant Marie Anne Gaudard, fille de Pierre Gaudard, seigneur de La Verdine, trésorier de France au bureau des finances de Bourges et commissaire des ponts et chaussées de Berry. Ils ont une fille, Victoire Pauline qui épouse le  Louis François Hélion de Barbançois (1750-1780), officier au régiment Royal-Pologne, fils du marquis de Sarzay, dont la famille possède le château de Villegongis.

Leblanc de Marnaval achète en 1763 la terre de Bouges et, deux ans plus tard, il fait raser la maison forte qui s'y trouve et construire le château de Bouges dont le fronton porte ses armes et celles de son épouse. Les travaux sont menés rapidement puisque l'affiche de la vente de 1781 indique que « le château est bâti à neuf depuis dix ans ». Le , des lettres patentes confèrent à Marnaval d'autorisation d'exercer ses droits seigneuriaux de basse, moyenne et haute justice et celui-ci fait dresser à cette fin, l'année suivante, un plan terrier de son domaine en 28 planches par l'arpenteur François Bonnin.

Le propriétaire ne cesse d'effectuer des travaux et améliorations dans son domaine. En 1778, il procède à une transformation d'ampleur des toitures : c'est peut-être seulement à cette époque qu'elles sont réalisées à l'italienne. L'allée cavalière est tracée après échange de prés avec divers particuliers. Des orangers sont placés sur les terrasses. Une volière et une fabrique trouvent leur place dans le parc.

Marnaval est accusé de détournement de fonds et tombe sous le coup d'un arrêt du Conseil du  qui le dessaisit sans indemnité de son bail de forges au profit de Jean François de Barandier Montmayeur, comte d'Esseville, qui obtient la concession du duché de Châteauroux et réclame une enquête sur les agissements de Marnaval, qui conclut que ce dernier sous-estimait les baux et s'enrichissait alors que les profits tirés des forges auraient pu être consacrés à la création d'un canal reliant l'Indre et le Cher à la Loire au niveau d'Orléans. Les manœuvres du comte d'Esseville ne tardent pas à être à leur tour dénoncées, le duché de Châteauroux réintègre le domaine de la Couronne en 1776 avant d'entrer dans l'apanage du comte d'Artois. Mais il est trop tard pour Leblanc de Marnaval qui doit se déclarer en faillite en 1778. Il est placé sous tutelle du syndic de ses créanciers qui le dessaisit du bail de la manufacture de draps de Châteauroux et le contraint à vendre la terre de Bouges, le  « avec tous les bâtiments, basse-cour y contiguë, l'orangerie, jardin, parc, terrasses, avenues et autres dépendances », ainsi que les ornements et le mobilier dont  livres de glaces. Son frère, Leblanc de Logny, la remet contre  livres à Jean François, marquis de Rochedragon, colonel d'infanterie, qui n'en disposera qu'à partir de 1781.

Sa femme, installée à Bourges est reconnue séparée de biens par un acte du , et portée au premier rang des créanciers dont l'assemblée comprend aussi ses deux frères, Leblanc de Coings et Leblanc de Logny, ainsi que son gendre, Charles Hélion de Barbançois, qui décède en 1780. Ruiné, Marnaval s'installe dans la paroisse de Saint-Denis à Châteauroux. À l'issue des ventes ordonnées par le syndic, il ne conserve que les dépendances de Balzence, Rouvres et Baudres avec les revenus afférents et une pension de  livres. Il se retire alors sur la métairie de Boisseloup sur la commune de Baudres, jusqu'à sa mort, le .

Notes et références

Sources
 Vincent Cochet, Le Château de Bouges, Paris, Éditions du patrimoine, coll. Itinéraires du patrimoine, 2004 -

Naissance en 1720
Décès en avril 1803
Industriel français du XVIIIe siècle
Maître de forges

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Hi, and welcome to my blog! I'm Susan E. Mazer -- a knowledge expert and thought leader on how the environment of care impacts the patient experience. Topics I write about include safety, satisfaction, hospital noise, nursing, care at the bedside, and much more. Subscribe below to get email notices so you won't miss any great content.
Florence Nightingale: On Nursing, Hospitals, and Hope
In 1996, my husband Dallas Smith and I were asked to do a presentation on Florence Nightingale. So, together with lots of her writings and books, we developed "Florence Nightingale: In Her Own Words" — combining Nightingale's words and our music to bring the telling of her story together with the emotional component that only music can deliver.
Until that time, I knew little about Florence Nightingale other than her title, "Mother of Modern Nursing." In fact, I knew little about why nursing became modern and what it was prior to Nightingale.
Since then, of course, I have learned over and over that the history of nursing is one that tells the tales of healthcare probably more than any other profession.
Doing this presentation now for so many years, I have come to feel that Nightingale is whispering in my ear. In costume and with what seems to be a channeled British voice, I have told her story in the first person as a means of bringing to life her intolerance for even one life ended because of, "what we neither knew nor practiced."
And, the knowing and the practicing may not come together even today.
As I look at the hospital of today – the most common assumptions we all make and what we accept as hospital practices, it is clear that nursing has undoubtedly progressed while the hospital environment has been victim to competing interests.
For example, Nightingale claimed that daylight and fresh air were critical to patient recovery. It took a study in 1984 by Roger Ulrich to attach the science to Nightingale's theory to change hospital construction standards to require patient rooms to have windows.
While fresh air is yet to be re-added to the hospital room, what is clear is that our ventilation systems are far from effective in ensuring that the air is as clean as needed.
Nightingale opened her School of Nursing at St. Thomas Hospital as the first secular school of nursing. Until then, all nurses were religious women or, as is today, sisters, daughters, wives, or mothers.
The profession has expanded dramatically. Today, one can be a certified nursing assistant, a registered nurse, a clinical nurse specialist, a nurse practitioner, or a doctor of nursing. These many levels of expertise play out at the bedside in dramatic ways, with nurse practitioners being able to not only examine patients but prescribe medications and perform many functions that were once limited only to physicians.
The relationship between nurses and doctors has been dramatized, with physicians portrayed as being heavy-handed and nurses as struggling to save their patients. This is not wholly true nor wholly false.
Nurses are the professional patient advocates – the individuals who take on ownership of the patient's journey from illness into recovery. The physician does not advocate in the same way; rather the physician diagnoses and authorizes treatment for the patient.
Even when a patient is in the hospital, the doctor does patient rounds, but nursing is done over the full 24 hours, being available in moments as the patient needs require.
Without exception, the physicians and nurses serving the needs of our communities are the heroes. Those who cannot or could not take the stress created by a system that continually monetizes the value of life and health – placing more value on illness than recovery.
The nurses are the ones doctors count on to take care of their patients. To patients, nurses are the voice of hope as well as the sure hand in relieving their pain and suffering.
One more thought: Intolerance for carelessness that carries with it a human price tag is not difficult to defend. If you read Notes on Nursing, specifically the footnotes, you will find Nightingale's pithy voice of such intolerance.
Again, neither difficult to defend or adopt. To give you an idea of her attitude and directness, her treatise, Notes on Hospitals, begins with:
It may seem a strange principle to enunciate as the very first requirement in a Hospital that it should do the sick no harm. It is quite necessary, nevertheless, to lay down such a principle, because the actual mortality in hospitals, especially in those of large crowded cities, is very much higher than any calculation founded on the mortality of the same class of diseases among patients treated out of hospital would lead us to expect.
I hope that the progress of nursing and medicine are forward – that science monitors and checks itself, and that nursing practice just keeps getting better and better.
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Wipeout Canada is RACIST because they didn't pick me! I'm Chinese, so they must hate Chinese people! Actually, that's probably not true at all....I think they didn't pick me because I wore glasses in my audition video. I can really see without my glasses! Ugh. Also, they're racist.
The callback interview/auditions(?) were last Thursday (July 22) at the River Rock Casino, and I was not invited. I saw the snippet they did on Global BC news that night and most of the people in line where (drumroll please....) white! Surprise, surprise! I bet all the show's producers are......WHITE! I think all the judges were white. Anyways, I saw one girl's face that was Asian-looking....other than that....nope. In all seriousness, I'm joking about the racist thing. I just like to stir up trouble because I have nothing else better to do. Or do I?
The main website claims that applicants shouldn't give up hope and that they will still contact people.....so I guess I should cross my fingers. One percent of me is actually really excited that I still have a chance! The other 99% is plotting vendetta. I mean, I didn't say that out loud.
PS - I love white people. I was just kidding, haha Chinese make the funny joke!


From childhood tragedy to leading voice among young entrepreneurs in Silicon Valley.
As the year ends, USA TODAY recognizes people in the news who embody these qualities. Today in Tech we profile Walker & Company Brands founder and CEO Tristan Walker. Even in Silicon Valley, where outsized ambition gives the biggest overachievers pause, Walker, 30, is betting he can use his know-how to take on industry giants and transform the health and beauty market for people of color. He has emerged as a rising star on matters of tech and diversity.
PALO ALTO, Calif. — Even here in Silicon Valley, where this generation's brightest minds dream up big ideas to smash the status quo, Tristan Walker's level of ambition stands out.
He is not building another social network or a mobile app to solve First World problems, say, how to order a gourmet dinner or hire a private car on your smartphone.
Instead, this 30-year-old is betting he can use his Silicon Valley know-how to take on industry giants and transform the health and beauty market for people of color.
His company is called Walker & Company Brands, and its first product is Bevel, a single-blade razor system for men and women with coarse, curly hair.
Walker says he's addressing the problem of razor bumps and skin irritation that affects up to 80% of African Americans and up to 30% of people of other races.
"It's crazy that no one has developed something like this in the hundreds of years that shaving has existed," Walker said.
Bevel started taking pre-orders in December 2013 and officially launched in 2014. Walker & Company Brands raised its $6.9 million Series A funding this year.
Bevel was inspired by Walker's own frustrations with shaving.
"I couldn't find products that worked for me, where I felt respected as a consumer, and I felt that needed to change," Walker said. "We feel like we are working on something really, really, really necessary and important for the world."
If the grateful e-mails he receives from customers are any indication, he's on to something. A single mom wrote to Walker that Bevel helped her teach her son to shave. A member of the U.S. Army said razor bumps had been as big a part of his military career as his uniform.
"Those are the only stories we need to hear to know we are on to something fairly significant," Walker said.
Yahoo executive Erin Teague says Walker, a top Silicon Valley executive who made his mark as head of business development at Foursquare, could have pursued any idea or built any company. Instead, he took a huge risk.
"Building a set of products targeted at people of color is not something people in Silicon Valley do," Teague said. "He is throwing all of his resources, energy, time and dedication into this company. This is his life's passion."
Walker & Company Brands is tucked away in a small but airy ground-floor office on a quiet Palo Alto street in the heart of Silicon Valley.
R&B tunes play on Sonos. Vinyl album covers — Little Richard, Al Green, Michael Jackson, Nas, Whitney Houston, Prince — line the conference room wall.
An inspiration wall features African-American greats such as Spike Lee and Ray Charles as well as a tender photograph of the NBA's Chris Paul and his young son and another photograph of a boy getting his first haircut. The newest addition: a restored 1920s barber chair.
The energy is palpable, lit up by Walker's broad grin, which he flashes regularly.
Something else is very different about this start-up. Silicon Valley companies are dominated by white and Asian men, but Walker & Company Brands has only one white man on the 15-person staff.
The staff is majority minority and majority women — and that is by design. Walker says it's a comparative business advantage.
"Our employee base really reflects the customers we want to serve," Walker said. "There is no shortage of research out there to suggest that more diverse teams lead to higher profits, and that is something we recognize in a very big way."
Silicon Valley is just now starting to face up to its diversity problem as companies look to compete in an increasingly diverse global marketplace. Just a tiny percentage of workers in major high-tech companies are black or Hispanic.
"I didn't know Silicon Valley existed until I was 24, and that's a problem," Walker said. "When I was growing up, I knew I wanted to be an actor or an athlete. I knew I wanted to work on Wall Street. Because they were archetypes I wanted to aspire to be like. In Silicon Valley, there were none, and I'd argue that there still are none. We have a lot of work to do to really build and create those archetypes to inspire a generation of folks to want to really participate out here in a big way."
Walker — who has emerged as the highest-profile African-American CEO and founder in Silicon Valley — is now that archetype. And he is using his success to nurture a new generation.
With Laura Weidman Powers, he co-founded a non-profit called Code 2040, which finds top Hispanic and African-American engineers and gets them internships with tech companies.
His reasoning: Black and Latino consumers are the greatest consumer demographic in the world. "Imagine America's competitiveness if we could help the greatest consumer demographic in the world be the greatest producing demographic in the world," he says.
Walker has come a long way from the rough neighborhood in Queens where he was raised. His father was shot and killed when he was 4 years old. His mom worked two jobs.
A scholarship sent him to Hotchkiss, an elite boarding school in Connecticut. The experience transformed him, he says.
He earned a degree in economics from Stony Brook in New York in three years. He was class valedictorian.
For two years, he traded energy derivatives for Lehman Bros. and JPMorgan, one of few black men on the trading floor.
He yearned to get away from New York, so he headed as far west as he could, enrolling at Stanford Business School.
An internship at Twitter opened his eyes to the power of technology.
"Twitter and Foursquare were changing our lives. I wanted to be a part of that," Walker said.
He e-mailed Dennis Crowley eight times asking for a job before the co-founder and CEO of Foursquare agreed to meet with him.
Crowley challenged him to sign 30 businesses in a month. Walker found 300 in a little more than a week.
Walker signed on at Foursquare as employee No. 3 and juggled working full time there during his second year of business school.
In 2012, Walker left Foursquare to become the first African-American entrepreneur in residence at venture capital firm Andreessen Horowitz. He rejected countless business ideas before landing on Walker & Company Brands.
Even with his credentials, investors did not readily open up their wallets.
"Raising money for a start-up is hard in general, but for us it was a little bit harder, particularly because a lot of the investors that we were pitching had no context about the problems we were hoping to solve," Walker said. "Again, if you think about Bevel, it's (addressing a) problem up to 80% of black men and women have. But the folks I was pitching weren't black men and women."
Undaunted, Walker has raised $9.3 million in funding from top investors, including Andreessen Horowitz and rapper Nasir "Nas" Jones, general partner with QueensBridge Venture Partners.
"When I heard the pitch for Walker & Company, I asked to invest before finishing my coffee," said Aaron Batalion, co-founder of LivingSocial and an angel investor. "One of Tristan's greatest strengths as a person and as a CEO is his authenticity. He realized that he, himself, and other young people of color, were being ignored by the companies that fill our store shelves."
Walker & Company Brands has more products planned for 2015 "in a big way," Walker says.
He won't say exactly what they are, but expect him to target what he calls "acute" health and beauty issues for people of color, everything from vitamin D deficiency to natural hair transitioning.
"You will never see us make shampoo for shampoo's sake," Walker said.
Walker says he's determined to change the world his infant son will grow up in. Avery James was born in September.
"When I think about the future that I want to leave for him, I really want him to do two things. No. 1, I want him to be treated as a consumer on equal footing with other consumers, not a second-class citizen but an equal. And secondly, I really want to inspire him to know that he can produce on equal footing with other folks as well," Walker said. "If I can do that, we will know that we've done something pretty important for the world. Because if we can do it for him, we can do it for a hell of a lot of other folks."
Even here in Silicon Valley, where this generation's brightest minds dream up big ideas to upend the status quo, Tristan Walker's level of ambition stands out.


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Excellence in business
Business faculty to hand out awards at annual celebration April 26
By Susan White
Leaders in aviation and advertising will be honoured by Memorial's business faculty at its annual Partners Celebration this month.
Joseph Randell (MBA'85), president and chief executive officer of Chorus Aviation Inc., will receive the 2016 Alumni Honour Award. Derek Langdon (B.Comm.'78) and Gary Wadden (B.Comm.'78), partners at group m5, will take home the P.J. Gardiner 2016 Newfoundland and Labrador Entrepreneur of the Year Award.
From left, Derek Langdon, Gary Wadden and Joseph Randell will receive awards from the Faculty of Business Administration at Partners on April 26.
Partners will be held April 26 at the Sheraton Hotel Newfoundland.
"I feel honoured to be recognized by Memorial's business faculty," said Mr. Randell. "This is very meaningful to me and reminds me of the value of my time at the university."
Chorus Aviation Inc. is an aviation holding company, based in Halifax, N.S., that owns Jazz Aviation LP, one of the world's largest regional airlines, and Voyageur Airways, a provider of specialized aviation services and aircraft leasing companies.
"The original research and marketing plan for Air Nova was developed as part of my master of business administration." – Joseph Randell
Jazz Aviation employs 4,100 people from coast-to-coast in Canada and flies to more than 70 destinations in North America. Its genesis, however, began at Memorial when Mr. Randell conceived of Air Nova. He had earlier begun his career in the airline industry at Eastern Provincial Airways in 1974.
"The original research and marketing plan for Air Nova was developed as part of my master of business administration degree," he said. "This has evolved through many forms to be what Chorus Aviation is today."
Mr. Randell completed his MBA in 1985 and co-founded Air Nova that same year, serving as its president. Later, he led the consolidation of Canada's regional airlines, which led to the creation of Jazz Aviation in 2001. Mr. Randell also studied engineering at Memorial before transferring to Dalhousie University to finish with an industrial engineering degree (a program not offered by Memorial at the time).
Commerce connection
The connection between Mr. Wadden and Mr. Langdon also began at Memorial, where they both studied marketing as part of the bachelor of commerce (co-operative) degree program. Later, they worked together in client/agency roles as Mr. Langdon was employed by the Department of Tourism and Mr. Wadden worked for an agency that was involved with the department's marketing efforts.
Mr. Wadden founded M5 Advertising in 1981 and Mr. Langdon joined as a full partner in 1985.
"Recognition of this nature is not something we are accustomed to receiving," said Mr. Langdon. "We tend to be focused on our business, the work we produce and our clients … We have never been about personal or company awards but there is a sense of satisfaction and accomplishment in being recognized by an organization that fosters and promotes entrepreneurship. It's a real honour to receive this business award."
Group m5 is an integrated communications company consisting of m5 Marketing Communications, MQO Research, m5 Public Affairs and Wavelight Productions. It's the largest communications company of its kind in Atlantic Canada, operating in four provinces as well as the United States and employing more than 200 people across its companies.
Group m5 also invests in many local charities and organizations including Choices for Youth, Team Broken Earth, Health Care Foundation, Camp Out Day and Big Brothers Big Sisters.
"We consider ourselves humble people [and] we have always stayed low-key personally," said Mr. Wadden. "But what I like about receiving this award is that others in Newfoundland and Labrador and beyond realize that it's possible to do your own thing and have a successful career."
Recognizing visionary leaders
Partners is the Faculty of Business Administration's annual celebration that brings together members of the faculty, business community, donors, alumni and students to pay tribute to those who have excelled in business while using their skills and expertise to contribute to their peers and communities.
"This year's award winners are excellent examples of the kind of business leaders we hope to pay tribute to with these awards," said Dr. Wilfred Zerbe, dean. "We are especially pleased that all of this year's award winners are alumni of our business faculty. It's a testament to the high-quality education and opportunities we provide here at Memorial University as well as to the hard work these individuals put into their businesses every day.
"Mr. Randell, Mr. Langdon and Mr. Wadden are all visionary business leaders and truly deserving of this recognition. They are excellent ambassadors for Memorial and we are pleased to be able to recognize their success."
For ticket information about Partners, please contact Wanda Whelan at wwhelan@mun.ca or (709) 864-2812.
Susan White is a communications advisor with the Faculty of Business Administration. She can be reached at susanwhite@mun.ca.


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Home | Entertainment
The Internet Thinks Game Of Thrones' Arya-Night King Scene Has An Indian Connection
The scene in which Arya stabs the Night King resembles a scene from Indian TV show Aladdin - Naam Toh Suna Hoga.
Entertainment | Indo-Asian News Service | Updated: June 18, 2019 16:12 IST
A still from Game Of Thrones 8 episode The Long Night. (Image credit: Hotstar)
The Internet suggested that GOT scene was inspired by the Indian show
Many users said that the Aladdin showrunners copied GOT scene
The final season of Game Of Thrones aired in May
It has been almost a month since Game Of Thrones aired its final episode but it seems fans are still gripped by the show's fever. Recently, a social media user pointed out a scene in the Indian TV show Aladdin - Naam Toh Suna Hoga, which resembled a sequence in David Benioff and DB Weiss' international show Game of Thrones.
The third episode of the finale season of Game Of Thrones saw Arya Stark jumping out of the darkness and killing the Night King with the dagger. The scene was hailed by some, while some fans criticised the sequence and created a pool of memes on social media.
One user on the website Reddit shared a video from an episode of Aladdin - Naam Toh Suna Hoga, and drew a parallel.
In the video, a skeleton is jumping at the lead actor and trying to attack him but the hero saves himself by grabbing the skeleton by its bones and stabbing it with a weapon. It is reminiscent of the killing scene of the Night King in Game of Thrones.
The video, which is now doing the rounds on the Internet, has left netizens in splits, with many saying that Indian makers have copied a scene from the Game of Throneswhile a section of social media users felt that the scene from Aladdin - Naam Toh Suna Hoga may have inspired the makers of the international show.
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)
India Vs New Zealand World Cup Semi-Final: Amitabh Bachchan Had A Good Laugh Over This Viral Meme Featuring Him
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Emmys 2019: List Of Nominations, Game Of Thrones Gets Record 32 Nods
San Diego Comic-Con 2019 Preview: Marvel, Star Trek, Westworld, and More
Game of Thrones Prequel Will Have Starks, Direwolves, Mammoths: George R.R. Martin
game of thronesarya night king


text:
RBA Inc
PPP Loan Data — RBA Inc, Wayzata, MN
Industry: Other Management Consulting Services
Location: Wayzata, MN
RBA Inc is a corporation located at 294 Grove Ln Suite 100 in Wayzata, Minnesota that received a Coronavirus-related PPP loan from the SBA of $2,679,200.00 in April, 2020.
RBA Inc in Wayzata, MN received a Paycheck Protection Loan of $2.68M through Bell Bank, which was approved in April, 2020.
For RBA Inc, the calculation used to estimate payroll costs is shown below:
Based on the standard PPP eligibility formula, it may be possible to estimate the payroll expenses represented by a company on their PPP application (see details above). In order to qualify for the PPP loan amount received, RBA Inc's 2019 payroll expenses are estimated to be at least $12.86M (not accounting for salary amounts > $100k).
On the PPP application, RBA Inc reported intending to use the proceeds of their PPP loan for the following expenses:
Because the loan received by RBA Inc is at least $2M dollars, it is subject to a full review by the SBA to ensure eligibility and compliance with PPP program requirements.
Business Information - RBA Inc in Wayzata, MN
294 Grove Ln Suite 100
Other Management Consulting Services
Hennepin County, MN — SBA Office 0508 — Congressional District: MN-03
Similar Companies near Wayzata
In the Wayzata area, 16 businesses in the "Other Management Consulting Services" industry received a PPP loan. These local businesses reported an average of 10 employees (compared to this company's 118) and received an average PPP loan of $209,939 (compared to this company's $2.68M).
She Rocks Research LLC
Inlay Insights LLC
Hale Management Services Compa
Customer Imperatives Group LLC
Summit Sourcing Group, Inc
Keelan Consulting, LLC
Gretchen Piper Consulting, LLC
Stephen L Peterson & Associates, Inc
Bridgeworks III LLC
Nationwide, 82,222 businesses in the "Other Management Consulting Services" industry received a total of $3.7B in PPP loans. This industry in total received less than 1% of the total PPP funding distributed.
PPP recipients in this industry report an average of 4 employees, 97% lower than RBA Inc's reported 118 employees, and received an average PPP loan of $44,991, 98% lower than this company's loan of $2.68M.
Source: www.federalpay.org/paycheck-protection-program/rba-inc-wayzata-mn


I think it would be helpful if I gave you, the parent an overview of the plan for spelling this school year. I hope no one is too disappointed 😉 but as an experiment this year we are dispensing with the workbook for spelling this year.
Why are we doing this in 2nd class?
We found that using a textbook was not efficient in helping us to reach our objectives. We found that we were teaching spellings that weren't sufficiently relevant to the individual child.
– spellings from the Dolch List of commonly used words.
especially words that sound alike but are spelt differently e.g. to, too, two.
We will supplement this work in class with exercises from 'Jolly Grammar'.
We will work on the Dolch list of commonly used words.
In theory if we study the Dolch list, there will be less of the children's own commonly mispelt words to learn subsequently.
A pretest on Monday to start the week.
It will be helpful to the children if we give them a pre test at the beginning of the week. I begun this experiment in the last term of the last school year. I found that a pre test is motivating for the children.
They will find if they do well they will have less words to 'learn' for homework. In order to keep the 'pre test' simple and straight forward, the children are asked to write down the spellings in isolation (rather than in the context of a full sentence).
I will refer to this as a 'pre check' when talking to the children. I try not to use the word 'test' with them as for some the thought of a 'test' can be stressful.
To put the word in context for the child, it will be called out as part of a sentence but we will only want the child to write the one word. To engage the children, the sentences may be humorous.
Using the names of children in the class in the sentences also keep them interested.
In this way the fortunate children who find spelling easy and whose time would otherwise be 'wasted' are identified quickly. Instead they will do 'free writing' at the back of these same spelling copies and 'have a go' at writing stories. Teacher will find reading this 'free writing' useful, in order to identify their 'commonly mispelt words'.
We will staple a photocopy of the Dolch word list into the copies. We hope the children will learn to use a highlighter to mark the spellings they get wrong in the pretest/precheck and have to learn. In this way children are learning to take responsibility for their own learning.
I found this very motivating for children last year. The numbers having to do regular spelling tests/check ups quickly reduced by a third as the students saw that if they did well they could write a story at this time instead.
The learning from the Dolch List will be checked daily and we will prioritize mastering these commonly used words.
Dictation; revising the Dolch List using stories based on the list.
Then to revise the words from the Dolch list teacher will dictate a story which features the Dolch spellings to all students.
There will be opportunities in doing this to address a certain amount of grammar and punctuation.
Last year, at this point, as these spellings had been already learnt, I found the numbers of children who needed to write out these stories as dictation fell away by two thirds very quickly. These children spent this time doing 'free writing' instead.
to work with a smallish group (ten or so) for whom spellings didn't come easy. I found spelling challenging enough myself as a student, so I hope I have an understanding of children who find spelling hard.
We will try to make this group work, learning the spellings in class as pleasant as possible. They will be working in a group of children whose ability was similar, so they won't be discouraged by the lucky children for whom spelling comes easy.
without needing to check back on the spelling hopefully.
– sound alike but are spelt differently e.g. to, too, two.
This work will be supplemented class with exercises from 'Jolly Grammar'.


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WANTED Dem bones, dem bones them crinoline bones...6 bones or walking cage.
I was told this weekend that my skirts were not bell like enough...not that I was the only one, mind you...I had been thinking about a 6 bone hoop, and I did see a walking cage that was nice, but not 250 bucks nice..
Anyone have a used one, or can point me to a reasonable priced hoop? I'd rather spend money on fabric!
Bumping this. Anyone out there with a set of crinolines they no longer use?


text:
Title: The history of the Buddhist Sangha in Ceylon from the reign of Sena I to the invasion of Magha
Author: Gunawardana, Ranaweera Appuhamillage Leslie Herbert
Awarding Body: SOAS University of London
Current Institution: SOAS, University of London
https://doi.org/10.25501/SOAS.00028543
The period of about four centuries from the reign of Sena I to the invasion of Magha is significant in the history of Buddhism in Ceylon primarily for the changes it brought in the organization of title sangha. In the ninth and the tenth centuries, the three nikayas of the Sinhalese sangha, which grouped monasteries spread over various parts of the Island under the leadership of three monasteries at the capital, reached the highest stage of their organizational development. As an institution owning extensive agricultural resources, the monastery of this period occupied an important position in Sinhalese economic organization. The immunities acquired in the ninth and the tenth centuries increased its income and extended its control over its tenants. The elaborate administrative system, devised for the new responsibilities of the monastery, was a vital factor which strengthened the cohesion of the nikaya. The loss of property by the monasteries during the period of Cola rule and again in the period between the death of Vijayabahu I and the accession of Parakkamabahu I affected the organization of the nikava; and its disintegration led to a new grouping of the sangha based on eight fraternities. The unification of the sangha in the reign of Parakkamabahu I was achieved by bringing these eight fraternities under a common leadership: it did not involve the suppression of the Abhayagiri and the Jetavana nikayas as has been hitherto supposed. Throughout the period under study, the sangha occupied an important position in Sinhalese society as its literati; as intermediaries in cultural contact with foreign lands; and as functionaries in the ceremonial and cultic practices of the laity. The reforms in the reign of Parakkamabahu I gave an impetus to the activities of the sangha. which is particularly evident in the literary works produced during the subsequent period and in the expansion of Sinhalese Theravada in South East Asia. They also created, for the first time in the history of the Island, a unified organization of the sangha.
10.25501/SOAS.00028543


text:
Personal Loan sonipat, 22 January 2020 from Lakshmi Vilas Bank
Advance Salary Loan from Lakshmi Vilas Bank in sonipat
The city of Sonipat is also a Municipal Corporation in the Indian state of Haryana. Situated at a distance of 43 kilometers from the capital city of Delhi, Sonipat is a part of the National Capital Region. The Yamuna marks the eastern boundary of Sonipat, which was earlier a part of Rohtak but was separated and made into a full-fledged district in 1972. Legend says that Sonipat was previously known as Sonprastha, which was modified to svarnaprastha or the golden city. Later, the name was shortened to Svarnpath, and eventually to its current form, Sonipat - also spelled as Sonepat. The Hindu epic Mahabharata says that Svarnaprastha was founded by the Pandavas. The district of Sonipat is divided into three regions - Khadar, Upland Plain and Sandy Region. The city is located on the upland plains. This area is rich in old alluvium, which is highly productive if properly irrigated. Wheat, rice, sugarcane, cotton, millet, oilseeds, pulses, barley, maize are abundantly cultivated at Sonipat using irrigation through tube wells and canals. Horticultural plants, vegetables and flowers are also cultivated. Dairy farming and animal husbandry form an essential part of Sonipats rural economy. Four industrial areas have been developed at Sonipat and factories of HSIIDC, Atlas, Birla Factory, OSRAM India, etc. have been set up. The Rajiv Gandhi Education City at Sonipat has been set up by the government that offers space to many universities for setting up their campus.
Low interest rate Premium Bike Loan in sonipat, 22 January 2020 from Lakshmi Vilas Bank
In 1926, seven businessmen of Karur founded Lakshmi Vilas Bank under the leadership of Shri V.S.N. Ramalinga Chettiar. They aimed to serve the financial needs of people who were occupied in trading businesses, industry and agriculture, in and around Karur. The bank was established on November 3, 1926, under the Indian Companies Act, 1913, and on November 10, 1926, it obtained the certificate to commence business. After the Banking Regulations Act was introduced in1949, the bank received its banking license from RBI and became a scheduled commercial bank? revealing its capability to operate as a full-fledged commercial bank. Lakshmi Vilas Bank did considerable expansion of its branch network from 1961 to 1965, when the bank took over nine other banks. The bank started the development of its branch network beyond Tamil Nadu in 1974 to take benefit from the additional opportunities across India. Thus, offices were established in the neighboring states of Karnataka, Andhra Pradesh, and Kerala, critical financial centres like Kolkata, Mumbai and New Delhi, as well as in other prominent business centers in Madhya Pradesh, Maharashtra, and Gujarat.