Langerhans cell sarcoma (LCS) typically presents as cytologic atypia and clinical aggressiveness and may involve multiple organs during the progression of the disease. Primary skin LCS without any extra-cutaneous site association is extremely rare and only a few such cases have been described in the literature. We present a case of unusual primary LCS in skin occurring in a middle-aged male patient. Physical examination revealed a large ulcerated cutaneous lesion and a smaller nodular lesion were located in the skin of the extensor side of his right knee. There was no regional lymph node or any other extra-cutaneous organ involvement. Histologically, typical large and pleomorphological tumor cells with epithelioid appearance and significantly malignant cytological features were observed to infiltrate in dermis and subcutaneous tissue. By immunohistochemistry, the tumor cells were positive for CD1a, S-100 protein and largerin strongly and diffusely. However, these cells were negative for CD3, CD20, CD21, pan-cytokeratin, HMB-45, Melan-A, and MPO. A diagnosis of primary cutaneous LCS was made. The patient received systemic chemotherapy of CHOP regimen, and was on a regular follow-up period for 12 months. There was no sign of relapse of tumor or any other extra-cutaneous organ involvement by whole body positron emission tomography/computed tomography (PET/CT) study. Because LCS is a high-grade malignancy with poor prognosis, it suggests that strict histological analysis and thorough radiographic examination are necessary for accurately diagnosing this tumor even if cutaneous involvement presented only.
According to the degree of cytologic atypia and clinical aggressiveness, Langerhans cell tumors are divided into two main subgroups: Langerhans cell histiocytosis (LCH) and Langerhans cell sarcoma (LCS) . LCS is a rare high-grade neoplasm with overtly malignant cytologic features and aggressive clinical course. It can occur at any age and may involve multiple systems or tissues. Skin and underlying soft tissue are the most common involvement, but other unusual locations, such as bone , lung , gallbladder and peritoneal lymph nodes  have also been described in the literature. LCS may be limited to cutaneous involvement or may progress to affect other organs. However, to our knowledge, primary cutaneous LCS without any extra-cutaneous association is extremely rare and so far only a few such cases with immunohistochemical and/or ultrastructural confirmation have been described in the literature [5, 6]. Due to its rareness in skin, the accurate diagnosis of cutaneous LCS could be difficult to be made because similar microscopic features may be encountered in metastatic cancer, malignant melanoma, anaplastic large cell lymphoma and myeloid sarcoma. Therefore, it is indeed a challenge for clinicians to make a correct diagnosis when the LCS presents as a solitary cutaneous mass because inaccurate diagnosis may lead to improper treatment. Herein we describe an additional case of primary cutaneous LCS arising in the skin in a middle-aged male patient without any extra-cutaneous manifestation in order to provide valuable information in this field.
A 48-year-old Chinese male visited his local hospital in May 2010 with a gradually enlarged and ulcerated erythematous plaque on his right knee. The patient stated that the lesion had been presented on the extensor side of his right knee for approximately 6 months and treated with a steroid ointment initially. However, the lesion gradually enlarged and ulcerated, and a new skin nodule presented with pain during the last few months. As a result, the patient was referred to our hospital for examination and treatment. Physical examination showed 8.0 cm×6.0 cm well-defined ulcerated plaque on the extensor side of his right knee. A solitary nodular mass, measuring 1.5 cm in diameter was also found near the large ulcerated lesion (Figure 1). There was no weight loss and no palpable lymphadenopathy or organomegaly. The laboratory results, including blood count, differential, liver and renal function, were within the normal range. A clinically presumed diagnosis was squamous cell carcinoma of skin. Surgical resection of the skin lesion without preoperative skin biopsy was performed. After diagnosis, the patient underwent polychemotherapy according to a CHOP protocol (cyclophosphamide, doxorubicin, oncovin, and prednisone) for six cycles. The skin ulcerated lesion regressed and the nodule became smaller in size. The patient was on a regular follow-up period for 12 months after chemotherapy. The bone marrow examination was performed 6 months after chemotherapy, but there was no abnormality found. Since there was a possibility of multiple organs involvement, the patient was referred to a whole body positron emission tomography/computed tomography (PET/CT) study to search the potential secondary tumor, but no abnormality was found. During the period of follow-up, there was no sign of recurrence of tumor and lymph node enlargement.
Physical examination showed a 8.0 cm×6.0 cm well-defined ulcerated lesion in the skin of the extensor side of his right knee. A solitary nodular lesion, measuring 1.5 cm in diameter was also found near the large ulcerated lesion (black arrow).
The surgical specimens, including large ulcerated plaque and small nodular mass, were routinely fixed in 10% neutral buffered formalin. The tissues were embedded in paraffin. Four micrometer-thick sections were stained with H&E. Immunohistochemical analyses were performed using the ChemMate Envision/HRP Kit (Dako, Glostrup, Denmark). The antibodies used in this study included a broad panel of antibodies against CD1a, CD3, CD5, CD20, CD21, CD30, CD38, CD56, CD68, CD79a, ALK, S-100 protein, Langerin, pan-cytokeratin, HMB-45, Melan-A, MPO and ki-67. The antibodies were obtained from Dako Cytomation (Dako, Glostrup, Denmark), Santa Cruz Biotechnology (Santa Cruz, CA, USA) and Novocastra laboratories LTD (Hong Kong, China).
For detection of Epstein-Barr virus (EBV) infection in the tissues, in situ hybridization for EBERs (EBV-encoded RNAs) was performed. The EBERs detection kit was purchased from Dako (Glostrup, Denmark). The detection process was conducted according to the manufacturer's instructions.
Under microscopic examination, the ulcerated lesion and solitary skin nodule shared similar histopathological appearance characterized by diffusely infiltrating of large tumor cells in dermis and subcutaneous tissue but epidermotropism was not appreciated. The tumor cells exhibited large epithelioid appearance with abundant eosinophilic cytoplasm and ill-defined cell borders. They had large oval to convoluted nuclei with nuclear groves and dispersed chromatin. These cells showed significantly malignant cytological features with active mitotic figure and multinuclear giant cells. Infiltrated neutrophils, eosinophils and lymphocytes could also been observed (Figure 2). The immunohistochemistry staining showed that the tumor cells were diffusely positive for S-100, CD1a, langerin and CD68, but negative for CD3, CD5, CD20, CD21, CD30, CD38, CD56, CD79a, ALK, HMB-45, Melan-A, pan-cytokeratin and MPO. Ki-67 proliferating index was high approximately 80% (Figure 3). EBERs detection demonstrated that there was no EBV infection in tumor cells. Taken together, these morphological and immunological data were consistent with a cutaneous LCS according to the WHO diagnostic criteria .
Photomicrographs of the cutaneous lesions. (A) Under low-power microscopic examination, the ulcerated lesion showed erosion of epidermis and diffuse infiltrating of large tumor cells in dermis and subcutaneous tissue. (B) The nodular cutaneous lesion was characterized by sheets of tumor cells in the dermis but the epidermotropism was not appreciated in the lesion. (C) Tumor cells were large epithelioid with large oval to convoluted nuclei and nuclear groves. (D) At high-power fields, the tumor cells exhibited significantly malignant cytological features with ill-defined cell borders and active mitotic figure (A and B, HE staining with original magnification ×40; C, HE staining with original magnification ×200; D, HE staining with original magnification ×400).
Immunohistochemical analysis of the cutaneous lesions showed tumor cells were diffusely positive for largerin (A), CD1a (B) and S-100 protein (C). (D) Ki-67 proliferating index of tumor cells was high approximately 80%positive (A-D, immunohistochemical staining with original magnification ×400).
Langerhans cell sarcoma (LCS) is a rare but distinct tumor derived from dendritic cell lineage. It was firstly recognized by Wood and colleagues in 1984 as malignant histiocytosis X to describe a rapidly fatal cutaneous mass with massive tumor infiltration of multiple organs occurring in an elderly male patient . In 1992, Tani et al. defined it as a "malignant neoplasm of Langerhans cells with the following criteria: (i) proliferation of typical Birbeck granule-containing tumor cells, and (ii) malignant cytological features such as atypia and frequent mitotic figures" . The classification of tumor of dendritic cells is indeed controversial, and there are overlapped features among various entities of the histiocytic and dendritic cell lesions, making definitive diagnosis difficult . According to the WHO classification, tumors of dendritic cell lineage include follicular dendritic cell tumors, interdigitating dendritic cell tumors, Langerhans cell tumors and other rare dendritic cell tumors. Langerhans cells and interdigitating dendritic cells share a common hematopoietic CD34+ precursor; in contrast, follicular dendritic cells do not have a hematopoietic origin. Langerhans cell tumors show expression of both CD1a and S-100 protein, however, interdigitating cells are positive for S-100 but negative for CD1a. Follicular dendritic cells express CD21 consistently, but never express CD1a. These specific immunophenotypes of tumor cells may be helpful to identify the accurate diagnosis of dendritic cell tumors. However, indeterminate dendritic cell tumor, a rare type of dendritic cell tumor and originate from the alleged precursor cells of Langerhan cells, is indeed difficult to distinguish from Langerhans cell tumor because both tumors consistently express S-100 protein and CD1a. By definition, indeterminate dendritic cells lack Birbeck granules on ultrastructural examination . However, not all cases diagnosed as Langerhans cell tumors had ultrastructural studies to confirm the presence of Birbeck granules. Ben-Ezra et al. reported that only 3 cases presented Birbeck granules among 9 cases of LCS . Deng et al. also described a cutaneous LCS without Birbeck granules and doubted it might be an indeterminate cell sarcoma . Therefore, it is possible that some previously reported LCS might be confused with indeterminate cell neoplasms, and indeterminate cell neoplasms are actually underreported.
Recent studies suggest that langerin (CD207) represents a very specific marker for Langerhans cells and derived tumors [4, 12], and it has been negative in reported indeterminate cell neoplasms [13, 14]. Langerin is a type II Ca2+-dependent lectin and induces the formation of Birbeck granules, the presence of which supports a Langerhans cell origin. However, Wang et al. recently demonstrating a langerin-positive LCS did not indicate Birbeck granules in the cytoplasm of the neoplastic cells on ultrastructural examination . Verdijk et al. found a lack of Birbeck granules in Langerhans cells to be associated with a mutation in the langerin gene . The lack of Birbeck granules under the electron microscopy might be due to the damage of Birbeck granules during histological process  or poor differentiation of tumor cells . Thus, langerin is a useful marker for distinguishing Langerhans cell tumors from indeterminate cell tumors even in Birbeck granules-negative cases [12, 17]. In the present case, we found that the tumor cells exhibited remarkably cellular atypia and higher mitotic activity with co-expression of CD1a, S-100 protein and langerin. This is consistent with a typical primary LCS in spite of the presence of Birbeck granules in tumor cells.
Despite its enigmatic histogenesis, LCS is an exceedingly rare tumor. To the best of our knowledge, only 30 LCS cases (including the present case) have been reported in the English-language literature to date [2–8, 11, 15, 18–24]. The age at the time of diagnosis ranged from newborn  to 81 years old  without gender bias. LCSs show a multiple organs involvement. Most of the patients had lymph node and skin involvement, although the lung, bone, mediastina, liver, spleen and heart can also be involved. The skin was the only organ involved in a few cases [5, 6]. Although most LCSs exhibited classical morphological and immunohistochemical features, individual cases showed unusual appearances, such as aberrant cytoplasmic CD3 expression and involving epidermis [15, 25]. LCSs are high-grade malignancy and show aggressive clinical course. Chemotherapy regimens have been demonstrated to be helpful to slow progression of LCS in various degrees. Radiotherapy has also been applied in several cases, but the effects remain uncertain. From the patients for whom follow-up data are available, 53.3% (16/30) died of their disease within 2 years despite conventional combination chemotherapy, surgery, and radiotherapy. However, 2 patients of 3 reported LCSs with only cutaneous involvement survived and were alive in complete remission (Table 1). In the present case, we found that the patient achieved a partial remission after chemotherapy and extra-cutaneous manifestation was not observed during the period of follow-up, although the follow-up period was not very long for the patient after therapy. These findings indicate that primary cutaneous LCSs without multiple organs involvement might have a somewhat smoldering stage. Once the tumor progress, dissemination of extracutaneous sites might be presented and the patient might gain a poor prognosis with aggressive clinical course. A recent study has demonstrated that some cases of histiocytic sarcomas do not pursue an aggressive clinical course, particularly cases with clinically localized disease, and the tumor size appears to be an important prognostic factor . In addition, Kawase et al. suggested that CD56+ Langerhans cell neoplasms share an aggressive clinical behavior and a worse outcome . For our reported patient, the tumor was localized but was large in size. There was no CD56 expression in tumor cells. It should carry an unfavorable prognosis. Of course, long-term follow-up should be performed to verify this postulation.
EM, electron microscopy; MA, molecular analysis; EMA, epithelial membrane antigen; CK, cytokeratin; MPO, myeloperoxidase; EBERs, Epstein-Barr virus-encoded small RNAs; PR, partial remission; NA, not available.
As its rareness in skin and poorly differentiated morphologic features, cutaneous LCS should be differentially diagnosed from other epithelial or mesenchymal malignancy of skin, including metastatic cancer, malignant melanoma, anaplastic large cell lymphoma and myeloid sarcoma. All of these diseases exhibit skin lesion and a frankly malignant cytologic appearance with highly aggressive clinical course and a poor prognosis, which may sometimes cause diagnostic confusion with LCS. However, cutaneous squamous cell carcinoma or metastatic cancer shows an obvious nest structure with epithelial phenotype, such as pan-cytokeratin, CK7 or CK20. Melanoma might share S-100 protein positivity, but also expresse other melanocytic markers, such as HMB45 and melan-A. Anaplastic large cell lymphomas are CD30+ and EMA+ and may show ALK positivity. Occasionally, myeloid leukemia can firstly present in skin, in which CD68 and lysozyme positivity could be observed and sometimes difficult to be distinguished from LCS. The presence of myeloid specific markers, such as MPO, CD117, CD99 and CD34 should be helpful in making a diagnosis of myeloid leukemia first presenting in skin or cutaneous myeloid sarcoma. In our case, the tumor cells strongly expressed CD1a, S-100 protein and langerin, which were Langerhans cell-specific marker, arguing against other cutaneous hematological neoplasma.
In conclusion, LCSs are extremely rare and only a few cases of LCSs with only cutaneous involvement have been reported in the literature. Our additive case also presented its rarity of site. The diagnosis of primary cutaneous LCS is difficult and should be made cautiously, particularly for those cases with clinically localized disease, but lacking the extra-cutaneous manifestation. LCS is a highly aggressive hematopoietic malignancy with poor prognosis. We suggest a long period of follow-up is necessary and radiographic examination is helpful for demonstrating organ involvement to inspect the progression even if the patient had complete remission at initial chemotherapy.
Yang Li, Bin Li contributed equally to this work.
YL and BL made contributions to acquisition of clinical data, and analysis of the histological and immunohistochemical features. They are co-first authors, and have an equal contribution to this work. XYT drafted the manuscript. ZL revised manuscript critically for important intellectual content and had given final approval of the version to be published. All authors read and approved the final manuscript.


This is terrific. Whatever is the opposite of AutoTune (AntiTune?) this uses it.
While not astonishingly attractive, there is something to admire about the confidence she has. Make me a hot teacher! Give me a class full of white-shirted cowboys preoccupied with dancing and looking away from me, the one woman around! That edginess gives her a bonus +2 points on the hottie scale.
She has difficulty standing upright, or walking in a straight line. Am left to guess that she has recovered from some trauma that gave her the gumption to fulfill a 20, 30 year-long dream to star in a music video. Bully for her! Don't dream it, BE it!
-3 points for controlling behavior, allowing for three seconds of a wandering eye and then, snap to attention, buster! Contemplate me and my odd fashion choices!
Actually, three seconds is more generous than some who would allow NO visual meandering. Maybe a sense of ovary competition gets her going. "Three seconds of looking at another woman, then I'm taking you HOME and will order you to do what I want." Maybe her album features tracks detailing what she demands in recompense for the three seconds her man's gaze strayed. Each second he stared leads to ten minutes complying with her demands. I'd listen to those songs, would probably stay away from those videos.


text:
BP CEO: Oil to start rebalancing in late 2016
Published: Feb. 10, 2016 at 5:44 a.m. ET
Sarah Kent
LONDON--The oil market should start to rebalance in the second half of the year but it will be some time before the $100 a barrel price is seen again, BP PLC's BP, -0.41% chief executive Bob Dudley said Wednesday.
Mr. Dudley said the oil giant is "very bearish" on the first half of 2016, but things will start to turn around in the third or fourth quarter.
"By that time, every storage tank and swimming pool in the world will be filled with oil," Mr. Dudley said, warning that a price recovery would likely start slowly.
Speaking at the International Petroleum Week conference in London, Mr. Dudley acknowledged that the mood was more subdued than usual.
He also spoke on another major challenge for the energy industry: new regulations surrounding climate change.
The oil executive warned that BP sees climate emissions growing by 1% a year to 2035, a level that would fail to prevent temperatures rising by more than 2 degrees Celsius (3.6 degrees Fahrenheit).
Write to Sarah Kent at sarah.kent@wsj.com
The reduction, which follows a similar move by Tesla, will allow the base model Mach E to qualify for a purchase tax credit.

redpajama_set_name: RedPajamaCommonCrawl


Canvas prints are an affordable way to display your photos and favorite art prints. The texture of the canvas creates a soft, appealing complement to your chosen image. This makes for a beautiful accent in your home or office.
Canvas prints are extremely easy to produce and an affordable option to add an artistic flair to your photo prints. Rather than a traditional framed photograph, you can use canvas to create modern home decor. If you prefer to showcase art prints, we can reproduce works of art with high-quality inks and high-resolution display.
We can print your canvas photo prints in high-quality UV inks in any colors.
Canvas prints are an excellent way to present your favorite photos. Printing a large photo print and finding a corresponding frame can also be costly. However, frames are not necessary on canvas prints, and they make for the modern office or home decor.
How are canvas prints made?
We print your image onto 17mm artist canvas that is fade and scratch-resistant. We then carefully mount and wrap the cloth over a wood frame. This material is also a museum quality canvas to ensure that your favorite moments are captured on gallery wrapped canvas as wall art for years to come.
How else can I display my photo prints?
If you don't love canvas material for your print, we have a variety of other materials you can print your pictures and art on. We have acrylic photo prints, metal prints, and even wood prints! You can also create other items out of your photos, like travel mugs, desk calendars, wall calendars, mousepads, and other photo gifts.
What if I want more than one design?
If you can't choose between your favorite memories, we can create a collage canvas for you! We'll arrange several images on the front of the canvas rather than one. A larger collage canvas accomplishes a lot with relatively little cost. That is because when you print a large gallery canvas, you display more of your photos for less!
What other photo creations can I make?
If you want to display your treasured memories anywhere other than a gallery wall, we can help. We can also help you produce photo cards, party invitations, birthday invitations, wedding announcements and more. Photo cards are also perfect for inviting guests to an engagement party, bachelorette party, or for bridal shower invitations. Finally, baby shower invitations look great with photo designs.
How can I display my canvas print?
Each canvas print comes with hanging hardware to mount it on the mall. However, easel back hardware is famous for displaying smaller canvas prints on tabletops or as centerpieces!
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text:
Nextbike West Midlands launch (Nextbike)
West Midlands seeking new bike-share supplier after only 25 out of 5,000 bikes were delivered
Nextbike struggled to find a corporate sponsor for the scheme
Fri, Jul 26, 2019 12:31
The West Midlands bike share scheme that was supposed to see 3,000 and 5,000 bikes made available across multiple cities and towns is looking for a new supplier after German firm Nextbike managed to deliver just 25. The firm has previously blamed technology issues and problems finding a sponsor for the scheme.
The scheme was originally due to launch in September 2018. However, in November it was announced that it would be delayed.
A pilot scheme was launched in Wolverhampton in February, but Birmingham Live reports that no further bikes were delivered.
The Express and Star reports that only around 1,100 individual rides have taken place, at an average of around seven per day.
A briefing note prepared by officials at Transport for the West Midlands stated: "Under the contract agreed last year, Nextbike committed to deliver 5,000 bikes across the West Midlands with the first batch arriving by September 2018, with the reminder rolling out in 2019.
"Despite numerous promises to get the scheme up and running to date it has only provided 25 bikes for a limited trial in Wolverhampton City Centre."
Nextbike is now said to be offering only a fraction of the 5,000 bikes agreed and West Midlands Combined Authority (WMCA) is thus terminating the contract.
Labour MP for Birmingham Hodge Hill, Liam Byrne, commented: "I don't know why our Tory mayor can't organise a cycling scheme in what was once the capital of Britain's cycling industry. But I know I speak for cyclists, old and new, when I say we'd like some answers."
A Transport for the West Midlands spokesperson said: "Transport for West Midlands (TfWM) has terminated its contract with Nextbike after persistent breaches by the provider.
"TfWM remains committed to providing a bike share scheme for the West Midlands and is considering alternative options."
Krysia Solheim, managing director of Nextbike UK, said: "Nextbike operates in more than 200 territories and is proud to be the most extensive bike share scheme in the world.
"Our track record is second to none and only yesterday we were praised in Parliament for the inclusivity and community-minded nature of our ground-breaking projects.
"We are understandably disappointed by WMCA's decision to terminate the contract and we have had extensive discussions with the team in Birmingham about how to make this work. While we have already outlined the reason behind some of the delays – none of which were in our powers to change – we remained truly committed to delivering a bike share scheme that the West Midlands would be proud of."
Speaking about the challenges the firm has faced last week, Solheim said: "We originally planned to have the scheme in full operation by the end of 2019.
"Finding one title corporate sponsor proved a bigger challenge than originally expected, so we decided to change our strategy to focus on regional and shared sponsorship."
She also said the firm had, "experienced an unfortunate difficulty in our global supply chain concerning a key element of the smart technology we use in our bikes," but said both issues had been resolved.
West Midlands Combined Authority
peted76 46 sec ago
Rendel Harris 1 min 35 sec ago
I experienced exactly the opposite, an increase in power, because the sanding removes the glaze that both impairs braking power and causes squealing.
LeadenSkies 1 min 53 sec ago
chrisonatrike 2 min 3 sec ago
muhasib 53 min 6 sec ago
"Frustrating" cycle lane parking getting worse, says councillor – in town where Daily Mail claimed motorists were being driven "off the road"
"Is that the unicycle lane?" Cyclists blast new painted cycle lane that's "narrower than a pair of handlebars"
Mathieu van der Poel outsprints Wout van Aert to win cyclocross world title after thrilling duel


text:
Q: Trying to dynamically create a data frame in R I have a vector of Strings that I wish to use as column headers for a data frame.
Example: cols <- c("A: Ike (N=428)", "F: Mike (N=691)", "G: Bike (N=380)", "Total (N=1499)", "p value")
I have a list of lists of lists of Strings that I want to add as the data from my data frame.
Example, 1st three rows:
[[1]] [[1]]$Female [[1]]$Female[[1]] [1] "151"   "35.3%"

[[1]]$`Age in Years` [[1]]$`Age in Years`[[1]] NULL

[[1]]$`Mean (SD)` [[1]]$`Mean (SD)`[[1]] [1] "59.7" "11.4"

[[2]] [[2]]$Female [[2]]$Female[[1]] [1] "280"   "40.5%"

[[2]]$`Age in Years` [[2]]$`Age in Years`[[1]] NULL

[[2]]$`Mean (SD)` [[2]]$`Mean (SD)`[[1]] [1] "60.3" "11.6"

[[3]] [[3]]$Female [[3]]$Female[[1]] [1] "152" "40%"

[[3]]$`Age in Years` [[3]]$`Age in Years`[[1]] NULL

[[3]]$`Mean (SD)` [[3]]$`Mean (SD)`[[1]] [1] "59.8" "11.5"

[[4]] [[4]]$Female [[4]]$Female[[1]] [1] "583"   "38.9%"

[[4]]$`Age in Years` [[4]]$`Age in Years`[[1]] NULL

[[4]]$`Mean (SD)` [[4]]$`Mean (SD)`[[1]] [1] "60"   "11.5"

[[5]] [[5]]$Female [[5]]$Female[[1]] [1] "0.190"

[[5]]$`Age in Years` [[5]]$`Age in Years`[[1]] [1] "0.614"

IOW, I want a data frame where column 1 is called names[1] and consists of frameLists[[1]].
Per the suggestions below, I changed my code to the following:
outFrame <- do.call(data.frame, c(frameLists, stringsAsFactors = FALSE))
colnames(outFrame) <- cols

Results come back looking like this:
  A: Ike (N=428) F: Mike (N=691) G: Bike (N=380) Total (N=1499) p value   NA     NA   NA    NA    NA
1            151            59.7             280           60.3     152 59.8    583   60 0.190 0.614
2          35.3%            11.4           40.5%           11.6     40%  1.5  38.9% 11.5 0.190 0.614

The results I want:
  A: Ike (N=428) F: Mike (N=691) G: Bike (N=380) Total (N=1499) p value
1     151, 35.3%      280, 40.5%        152, 40%     583, 38.9%   0.190
2                                                                 0.614
3     59.7, 11.4      60.3, 11.6      59.8, 11.5       60, 11.5

A: Assuming all the lists have equal number of string inside, try
result <- do.call(data.frame, c(lapply(frameLists, unlist), stringsAsFactors=F))
names(result) <- name

Example data of list of lists (not sure if this is what you meant, please provide sample data otherwise) and vector of name
frameLists <- list(list(c("asd", "faf"), NULL, c("3", "2")), list(c("aaa", "zzz"),NULL, c("1", "3")), list(c("qw", "gs"), NULL, c("3", "2")))
name <- c("a", "b", "c")

Output
> result
    a   b  c
1 asd aaa qw
2 faf zzz gs
3   3   1  3
4   2   3  2
> str(result)
'data.frame':   4 obs. of  3 variables:
 $ a: chr  "asd" "faf" "3" "2"
 $ b: chr  "aaa" "zzz" "1" "3"
 $ c: chr  "qw" "gs" "3" "2"

Another possible interpretation (not sure what output you want) of the same input:
res <- as.data.frame(do.call(cbind, lapply(frameLists, function(x) do.call(cbind, x))), stringsAsFactors=F)

Output is
> res
   V1 V2  V3 V4 V5 V6
1 asd  3 aaa  1 qw  3
2 faf  2 zzz  3 gs  2
> str(res)
'data.frame':   2 obs. of  6 variables:
 $ V1: chr  "asd" "faf"
 $ V2: chr  "3" "2"
 $ V3: chr  "aaa" "zzz"
 $ V4: chr  "1" "3"
 $ V5: chr  "qw" "gs"
 $ V6: chr  "3" "2"

A: Your code doesn't work because you initialized results as an empty data frame, which R takes to be a data frame with 0 rows and 0 columns. When adding a column to a data frame, its number of rows must match the existing frame's. That's why you got the error message replacement has 2 rows, data has 0.
It'd easier to bind a list of columns together into a dataframe all at once. Problem is, the data.frame function doesn't want a list, it wants each column as a separate argument:
data.frame(c(1,2,3),c(4,5,6),c(34,1,1)).
How can you make data.frame take a list of columns rather than multiple arguments?
That's what do.call is for!
Give do.call a function and a list of args, and it deals the args to the function one at a time.
colList <- list(c(1,2,3),c(4,5,6),c(34,1,1))
col_names <- c('a','b','c')
df <- do.call(data.frame,colList)
colnames(df) <- col_names

Result:
> df
  a b  c
1 1 4 34
2 2 5  1
3 3 6  1

Works equally well if colList is a list of vectors of strings, but you may want to use stringsAsFactors = F to avoid factor conversion by data.frame.

A: Built the following to meet my needs.  It's clunky, but so far it works.  First: the output:
> myDF
             A: Ike (N=428)   F: Mike (N=691) G: Bike (N=380) Total (N=1499) p value
Female           151, 35.3%        280, 40.5%        152, 40%     583, 38.9%   0.190
Age in Years                                                                   0.614
Mean (SD)        59.7, 11.4        60.3, 11.6      59.8, 11.5       60, 11.5
Q1, Q3               53, 68            52, 69          52, 68         52, 68
Range                27, 88            19, 88          26, 85         19, 88

Now the code that generated it:
#' Make a data.frame given the column headers and data to fill the data.frame
#'
#' @param cols          Vector of text holding the column names
#' @param frameLists    List of lists holding the data for the data frame.  First list element
#' must have all the names used in frameLists. Must be as many lists in frameLists as there are
#' Strings in cols
#' @returnType  Data Frame
#' @return  Data Frame with all the elements set up and filled in
buildFrame <- function (cols, frameLists) {
    outList <- list()
    for (col in cols) {
        outList[[col]] <- NA
    }

    outFrame = data.frame(outList, stringsAsFactors = FALSE)
    colnames(outFrame) <- cols

    outList <- list()
    for (col in cols) {
        outList[[col]] <- list()
    }

    theNames <- names(frameLists[[1]])
    whichCol <- 1
    for (topList in frameLists) {
        colList <- outList[[whichCol]]
        for (aName in theNames) {
            data <- topList[[aName]]
            if (is.null(data)) {
                colList[[aName]] <- ""
            }
            else {
                colList[[aName]] <- data
            }
        }
        outList[[whichCol]] <- colList
        whichCol <- whichCol + 1
    }

    outFrame <- rbind(outList, outFrame)
    outFrame <- outFrame[-1 - length(theNames), ]
    rownames(outFrame) <- theNames

    return(outFrame)
}

redpajama_set_name: RedPajamaStackExchange


Software for scheduling, co-ordinating and billing property services.
Centrally managed and with seamless communication to a mobile work force.
1. Is responsible for logging the existence of a reported problem.
2. Needs to manage this problem effectively through to its resolution.
3. May have mobile technicians who are part of your solution.
4. May wish to bill for some or all of the services rendered.
5. May be a single PC office or a large corporation.
• An "out of the box" solution that can be configured by you, to meet your individual needs.
Comprehensive search screens enable customers to be found and their queries to be answered promptly, without having to phone them back!
Property Services is designed to enable jobs to be scheduled in three different ways.
1. The office decides and schedules everything.
2. The technician decides and schedules everything.
3. The third and most flexible is where the office schedules the jobs when required but leaves the technician to schedule the remaining.
The scheduled dates, full job details and job notes along with work carried out to date can be viewed by the office, the associated manager and designated technician.
Below is the office administrator's view where the quick filters are being used to show unscheduled critical jobs so that they can assign to the technicians.
Most customers would find an estimated start date useful. Based on the jobs priority status, existing work scheduled and hours worked per day Property Services can estimate the approximate date and time of attendance.
If a customer requests and you are able to offer a fixed appointment you can schedule the job there and then.
The software is clear and unambiguous ensuring that completion of the required information (time taken and materials used) is quick and easily after only minimal application training.
Below you can see the technicians screen for assigning outstanding jobs to his diary.
Manager roles can also be defined. The manager will receive copies of all jobs that have been allocated to their defined team enabling them to monitor progress and work completed.
The pricing of invoices is highly configurable from within the Property Services.
Different Labour types can be priced as £x for the first hour and then £y per additional hour.
Material pricing is configured again in the set up area. A mark up from cost for each category type can be defined.
Alternatively any job can have a fixed price assigned to it.
At any point an operator can select to create invoices.
Where a customer is happy to receive a consolidated bill, this can be defined within the software.
Invoice Import File for other ERP systems.
The software can not only be producing invoices within Sage 50 but also enables effective integration with many other management account suites.
All completed jobs can be viewed offering a complete history of works.
We have designed our solution using simple, robust web objects. These can sit on most office computers and servers that run the Microsoft operating system. This can therefore be an existing single PC, part of your existing corporate solution or a new computer, provided by us with everything installed ready to go.
Property Services is been designed from the outset to be highly configurable ensuring that it can meet your particular needs.
Where you may have any further requirements, as the authors, our in-house development team can deliver a detailed proposal.
Virtually every element of the package can be tailored to reflect your business processes.
We have designed the Project Manager security to be easily managed and to meet the needs of most large organisations.
Property Services has a growing list of standard documents and reports that can be produced to organise and present the wealth of information held within the software. The reports can also be exported in many different formats.
The standard documents and reports can be amended to suit your design equipments. You can also generate your own reports from scratch and define the security level required.
If you want to benefit from using the communication features, all you will need is a normal broadband connection at your office with a router and your external technicians need a device running Microsoft Windows 7 or above with internet access.
For further information or to arrange a demonstration please contact us.


text:
Q: extract all the headings(titles) from a ppt slides I am looking for code to extract only the titles from every power point slides. Is there any python function available. Any help is appreciated.

A: Not by Computer vision (this would be more complicated)
But using some libraries it is possible:
from pptx import Presentation

filename = "test.pptx" #your ppt filename

prs = Presentation(filename)

for slide in prs.slides:
    title = slide.shapes.title.text
    print(title)

Source: How to read PPT titles
Don't forget to install the library:
pip install python-pptx

A: in previous versions there was a function like this buitl-in. But it has been abandoned.
But if you right click in the Outline view you can choose collapse all, which will give you only the highest level. Then you can copy paste, the slide number of course will not be there, but if you paste to Word every title will be a paragraph so applying a number should do it


TO KICK OF OUR NEW RELATIONSHIP WITH GLOBAL GIANT, COTTON ON, WE HELPED LAUNCH THEIR FIRST EVER STREET WEAR COLLECTION, AMONG EQUALS.
AMONG EQUALS' LAUNCH MARKED A NEW DIRECTION FOR THE BRAND, DRAWING INFLUENCE FROM URBAN STREETWEAR AESTHETIC TO CAPTURE THE FEEL OF INNER CITY YOUTH. LOCAL DESIGNER, DAN TUPARI, TRANSLATED THIS INTO THE DEBUT COLLECTION, WHERE RAW WERE BROUGHT ON TO MANAGE THE LOCAL PR + MEDIA ACTIVITY, WORKING WITH LOCAL INFLUENCERS, MEDIA + A COLLAB WITH HYPEBEAST TO SPREAD THE GOOD WORD FOR THIS BRAND NEW LABEL.


text:
Home plate umpire Tony Randazzo leaves game in…
Home plate umpire Tony Randazzo leaves game in 14th inning
PUBLISHED: May 13, 2017 at 2:34 a.m. | UPDATED: July 27, 2018 at 6:12 a.m.
SAN FRANCISCO (AP) — Home plate umpire Tony Randazzo left the game between the Cincinnati Reds and San Francisco Giants before the top of the 14th inning.
Randazzo was hit directly in the mask by a 91 mph fastball from San Francisco's Johnny Cueto in the fifth inning but remained in the game until after the 13th inning Friday night. Second-base umpire Clint Fagan took his place.
Randazzo originally got hurt when Billy Hamilton squared to bunt Cueto's pitch but pulled the bat back at the last minute. Catcher Buster Posey couldn't get his glove on it and the ball hit Randazzo and knocked him straight to the ground. Giants trainer Dave Groeschner rushed out to check on Randazzo.
More AP baseball: apnews.com/tag/MLBbaseball
Sports briefs: Archie Williams in control of playoff destiny
Sports in Marin: Thursday, Friday


text:
U.S. Dash To Top Gas Exporter Spot Continues
by Tim Daiss November 22, 2019 November 22, 2019 03074
LNG carrier with Logan Airport in background
Image by lightgraphs
The U.S. is continuing its breakneck dash to the top of the liquefied natural gas (LNG) exporters club, but that momentum is still being threatened by the ongoing trade war between the U.S. and China.
On Thursday, the Federal Energy Regulatory Commission (FERC) said it had approved the construction of four LNG projects and related facilities to export natural gas from the U.S.
The FERC approved NextDecade's 3.6 billion cubic feet/day (bcfd) Rio Grande project, Cheniere Energy's 1.5-bcfd Corpus Christi Midscale, Exelon Corp.'s 0.8-bcfd Annova LNG Brownsville, and Texas LNG's 0.3-bcfd Brownsville.
All four LNG project sponsors have applications pending before the U.S. Department of Energy (DOE) seeking authorization to export gas to non-Free Trade Agreement (FTA) countries.
"The Commission has now completed its work on applications for 11 LNG export projects in the past nine months, helping the U.S. expand the availability of natural gas for our global allies who need access to an efficient, affordable and environmentally friendly fuel for power generation," FERC Chairman Neil Chatterjee said in a release.
Second Phase Push
The FERC approvals also mark the continued push of the so-called second phase of the U.S. LNG juggernaut that has the potential to rival both Qatar and Australia as the world's top LNG exporter by the mid part of the next decade. However, that possibility is in jeopardy as the trade war between the U.S. and China nears the 1-½ year mark.
For the U.S. LNG sector to reach its full potential, it needs a plethora of help from China in both the signing of long-term offtake agreements so several project proposals can reach the all important final investment decision (FID), as well as funding from Chinese financial institutions.
The longer the trade war persists the greater the chance that it will negatively impact the U.S. LNG sector for the long-term, thus causing a loss of potential global LNG market share to not only Qatar, and Australia, including market share in the Asia-Pacific region, which accounts for two-thirds of global LNG demand, with that amount forecast to increase going forward, but also to Russia as it ramps up its LNG export sector as well as a host of other smaller and ambitious LNG exporters.
Notwithstanding, one noteworthy significance from yesterday's FERC approval is that the Texas LNG project is a so-called mid-size project at 4 million tons per annum (mtpa) of liquefaction capacity. Some in the industry maintain that mid-scale LNG projects range up to 3 mtpa, but the Texas LNG project was intentionally designed with mid-scale in mind, which has advantages over larger scale LNG projects, including quicker speed going to market, LNG offtake flexibility, efficient use of capital, and creative technical solutions. According to Texas LNG, the project will also promote a low-risk tolling model which will optimize gas price arbitrage between Texas and global markets.
As of June, Texas LNG had signed a number of non-binding agreements with Chinese, Southeast Asian and European customers for cumulative total volumes exceeding phase one volumes of 2 mtpa. These customers are a mix of state-owned and private enterprises, the company said.
Texas LNG is also in discussions with additional potential offtakers, including traders and portfolio players, according to the company. Moreover, marketing for full capacity of 4 mtpa is also is underway with negotiations of binding agreements expected to be completed prior to ground breaking in 2020.
"The World Is On Fire": CD Media Interviews Steve Bannon
The Hi-Tech Traditionalist: Emasculated Mutilated Castrated American Christianity And Judaism Are Holding Hands As They Are Jumping Off The Cliff Of Oblivion
FERCLNGnatural gasTexas
BREAKING: Former Ukrainian MP Alleges Biden Family Received $12M Kickback From Transaction With Burisma Owner To Kill London Criminal Cases, Provides Details To DOJ
Tim is an oil markets and geopolitical analyst, journalist and author that has been working out of the Asia-Pacific region for more than ten years. He's worked for Forbes, S&P Global Platts, Interfax, NewsBase, and the UK-based Independent newspaper. He's also authored geopolitical reports and analysis for Association of Southeast Asian Nations (ASEAN) defense ministries. His analysis and news reports have been cited in media outlets around the world, including in the US, Japan, China, Vietnam, the UK, and Russia and have been translated into several languages and used in television news reports.
Productivity Drops More Than Expected
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You probably don't have many post-menopausal white women in your fan base. The only reason I know who you are is because I read US Magazine on the treadmill. For that reason, I know that you sort of ruined Taylor Swifts's big moment at the Grammys and that you are Kim Kardashian's Baby Daddy. I also know about your interview with Ryan Seacrest, because of Yahoo News.
Yahoo News is filled each day with items that have nothing to do with my actual world, like talking dogs and the world's largest baby, and the fact that Will Smith's 15-year-old son has gone public with his relationship with his 16-year-old girlfriend who is the daughter of Bruce Jenner Kardashian, I try to bypass these items, in order to get to my mailbox. But each day, at least one headline accounts for me checking my mail about 30 seconds after I intended to do so.
Last week, I was sucked into your interview with Ryan Seacrest, in which you blamed "classicism" for your not being able to achieve all of your goals in life. I'm not sure what "classicism" is but if it means "lack of class" I'm on board with your statement.
You also said that no one cares if Michelle Obama Instagrams a picture of herself in a bikini. I completely agree with that statement as well. We live in a pretty fucked up world, Kanye. There are few things nowadays that give me any hope for the future. But I have to say that one of them is that the American public sees the First Lady as being more than booty.
I think maybe you are confusing popular culture with culture. Most of us love something about popular culture, whether it be following fashion or sports, or picking up the latest fare from some author of international thrillers to read on the beach. We watch reality shows and we vote for American Idols. We read everything we can about Wills and Kate. Popular culture is available to all of us. We don't have to be talented or smart or wealthy to be fans.
Culture is something else. Culture is human intellectual achievement. It is what defines a society, the legacy we leave to the generations that will follow. When we look at the Roman Empire, Pharaonic Egypt and the ancient dynasties of Asia and the Middle East, we marvel at the feats of government, the arts and engineering that created nations from tribal societies. The internal violent and sexual shenanigans of many of the rulers of these civilizations is no doubt a fascinating sideline, but it in no way defines the civilizations that these people created and ruled.
Your fiance probably has more Twitter followers than the First Lady. Hell, she might even have more followers than the president. But our fascination with her is limited to the externals of her life: her face, her body and the clothes she puts on it. She is a fantasy, whether one's fantasy is for giant booty or designer duds. The best you can say about her is that she has turned her ability to showcase her body parts into a lucrative profession, indeed.
The fascination we have for Michelle Obama has nothing to do with what she looks like or what she wears (although an attractive First Lady is always more interesting). When we look at Michele Obama, we think about her intelligence, her strength, her ideals. No matter your political affiliation, you have to admit that Michele Obama is a powerhouse. Your girlfriend reminds us of what one can do with the gift of outstanding good looks. Michelle Obama reminds us of what one can do with outstanding intellect and drive.
So Kanye, draw Kim and North close to you. Tell them that you love them and that they are the most important people in your life. And be grateful that you live in a society that worships celebrity to such a ridiculous degree that someone like you, someone who sets the bar ever higher for pretention and self-absorption, can be worthy of taking up space with talking dogs and giant babies.


text:
Home Voices The Exchange Critical Theory and Precursors to Approaching Critical Race Theory
Critical Theory and Precursors to Approaching Critical Race Theory
Sherelle Ducksworth
A Note from Ed Stetzer: We are launching a series on Critical Race Theory. It's an important conversation today, since many are using the description and meaning different things. At the Wheaton College Billy Graham Center, we are committed to help Christians know and engage the culture with biblical discernment, so we are launching a conversation with, well, different views. As Christians, we want to think through these things together, and the series will include not just one opinion, but several.
We started with a positive framing, and will include others who are more negative, and some in the middle. All will come from evangelicals. And, it is important that we hear from people of color, and, in this series, not all people of color will agree. It's a conversation— mature, Christ-like, and God-honoring. We hope it serves you and your church well.
To start it off, I asked Sitara Roden from my team to give us a framing article. Now, we are dropping articles, pro, con, and others on a continuum, modeling Christian dialogue and learning. Our first contributor, who will be sharing a three-part article, was Dr. Pat Sawyer, with references to be shared at the conclusion. You can read part one here, part two here, and part three here. Then, we heard from D.A. Horton, as he shares a four-part article of his examination of CRT. You can read part one here, part two here, part three here, and part four here. Now, we will hear from Sherelle Ducksworth. Read part one of her contribution here, and part two below.
by Sherelle Ducksworth
In Part I, we walked through four precursors about sociological theory to consider before engaging Critical Race Theory (CRT). Those precursors included understanding that:
Sociological theories are suggestions on how to see the world.
Sociological theories show us what to look for in the world.
Sociological theories morph into a multitude of ideas and assertions.
Sociological theories are descriptive but are used with research orientations that aim at prescribing solutions.
Since CRT traces its lineage to critical theory, it will be helpful to grasp some tenets of critical theory that will help us draw conclusions on how to approach critical race theory.
1. Critical theory utilizes an oppressor/oppressed binary in its investigation and interpretation of the social world.
The roadmap for sociological analysis for critical theory is a fixed binary of oppressed versus oppressor. These two groups exist in conflict, tension, and struggle as the oppressed group seeks liberation and the oppressor group seeks to maintain the status quo and their social dominance. Critical theory challenges the notion that society is "fixed" in hopes of removing the traditional norms and ideologies that allow the oppressor group to maintain power and privilege.
Previous articleVoices With Ed Stetzer: Social Justice, Critical Race Theory, Marxism, and Biblical Ethics
Next articleJesse Duplantis Claims Donations Can Speed the Return of Christ
Sherelle Ducksworth is a native of Clarksdale, Mississippi and currently serves as a sociology instructor at Louisburg College in Louisburg, North Carolina. She earned an AA degree in general education from Coahoma Community college, her B.A. degree in sociology from Mississippi Valley State University, her M.S. degree in sociology with a concentration on social stratification from Mississippi State University, her M.A. in theology from Mid-America Baptist Theological Seminary and is currently working on a Ph.d in systematic theology at Southeastern Baptist Theological Seminary. Her and her husband Aaron currently live in Wake Forest, North Carolina and attend Christ Our King Community Church in Raleigh, North Carolina.
A Somber Anniversary
On Martin Luther King, Jr. Day: "Paul's Letter to American Christians (From MLK)"
Biblical Literacy by the Numbers, Part 3: Fixing the Problem
Biblical Literacy by the Numbers, Part 2: Scripture Engagement
Biblical Literacy by the Numbers, Part 1: The Challenge
Ed Stetzer: 'Cancel' the Salvation Army? I Think Not.
Ed Stetzer: The Church and Donald Trump: We Need Christ at the Center of Our Services, Not Democrats, Republicans or Any Other Politician
Choose Faith at Christmastime
Church Attendance During Christmastime: Stats on Christmas Outreach
Sharing Christ at Christmas: What the Stats Say


text:
Home › Forums › NMA › NMA News and Information ›
Crimea hits IndieGogo
Discussion in 'NMA News and Information' started by Tagaziel, Oct 2, 2014.
Tagaziel Panzerkatze Staff Member Admin Orderite
Crimea, a Polish indie RPG, has just hit IndieGogo in a bid to secure funding for the further development of the project. The current goal is $37,500 in 40 days.
What makes Crimea interesting? Unlike most other projects, the game is already being developed and is in a fairly advanced state: A playable demo showcasing the technology and the general gameplay is available for download on IndieDB. As it goes, you can try it before you buy it.
Link: Crimea on IndieGogo
Last edited by a moderator: Jan 9, 2016
Tagaziel, Oct 2, 2014
AtomBomb It Wandered In From the Wastes
Not going to lie, doesn't look half bad. I'm not sure how possible it is for me as an english-speaking American to play a foreign game though
AtomBomb, Oct 4, 2014
Krai Mira First time out of the vault
There are a lot of 'foreign games' you can play without vocabulary - Call of Juares, Commandos, Painkiller... It's just a matter of quality translation which is not a high priority for the tech demo. Currently the only non-English sounds are voices of enemies that don't affect game mechanics.
Krai Mira, Oct 4, 2014
BigBoss Your Local Scrub
So I'm guessing at the end of the game-development you guys will focus more on English translation? Hook me up with a translator and I'd be willing to help you guys out in translating it to English (I mean, your translator will tell me the "English" version of what you want to say, and I'll help you translate it further into more, well, "English-sounding" English. Meaning you won't find lines in the game that say "You jump in back of truck now!" like in Metal Gear for the MSX. Granted though, like any game when translating it to a different language, the script will change a bit. Look at MGS 1 for example.
And I promise, no drinking on the job....
Alright I don't promise that but I swear I'll get stuff done.
BigBoss, Oct 4, 2014
223Pistol First time out of the vault
do i get to see Natalia Poklonskaya ?
223Pistol, Oct 6, 2014
alec White heterosexual male Orderite
I sort of feel sorry for these guys when I see that they only raised $155 in one week. I know they have five weeks left, but it doesn't bode well. If the next five weeks are the same as the first one, they won't even have raised a grand when their IndieGogo ends. And they need $37,500.
alec, Oct 7, 2014
Diospyros First time out of the vault
I was kind of thinking the same thing. I'm sure the funding will go up more especially in the last few days, but unless someone gives them a bigger push than NMA can I don't see it happening. But if it fails hopefully they will try again.
As odd as it may sound, I also wonder if the amount they are asking for is too small to attract donors. When I see someone asking for $37,500 for a full fledged video game I think "wow, that's cheap" and it makes me nervous the final product will look cheap too. I mean Wasteland 2 is a good comparison in that Crimea, like W2, are trying to make a modern game that has the look and feel of the late 90s classics (most obviously Fallout). But they had millions of dollars to work with. These guys are trying to do it on 1/100th as much money. I'd love to see them come out with an enjoyable game (even if it is smaller and less polished than W2) but it is hard to envision the money and the developers ambition aligning.
Diospyros, Oct 7, 2014
Diospyros said: ↑
As it was said on the indiegogo page $37,500 is the sum for the basic version of the game.
"Goal #1 (default version) - $ 37 500
A player will follow a predefined sequence of locations, with the ability to enter so called 'random areas' from the global map. The gameplay will be focused on fighting. You will also be able to gain experience, improve your basic skills, buy equipment and take quests that will follow you through the main storyline."
This version boils down to linear story and basic player's parameters that can be enhanced when you gain some experience. Taking into account that we already have developed significant part of battle mechanics and have some content, we plan to distribute costs on buying 3D content on Turbosquid, payment for irregular freelance work and software licenses. This will allow our tiny team to work 1.5 years on the project.
There are also so called 'Stretch Goals', and current state of the development requires to determine which version we will choose before we start adding new locations. Expanded version is more interesting of course.
Crni Vuk M4A3 Oldfag oTO Orderite
maybe another problem is that there are pretty many post-apoc-wasteland games out there, or at least games that go in a similar direction, particularly if we are talking about role playing games. I mean just look at the sher number of games that are either in the works or saw some release. And I hope you dont get this the wrong way, it is simply my honest feeling, but the project doesnt strike me as something unique. If you have to decide where to spend your money, then you have to sometimes prioritise, just like every investor does, because there simply are way to many interesting projects out there, and there is only so much money people can spend on video games. Though with saying that I really hope that you can get your project to work and that you will get teh funding. After all, I am nothing more then just some random idiot rambling on the internet.
Crni Vuk, Oct 9, 2014
drawnacrol It Wandered In From the Wastes
A big problem is people just got Wasteland 2 and aren't going to be even thinking about another old school post-apocalyptic game for a long time. With Tides of Numenara and Pillars of Eternity coming out soon I won't be backing anymore games until I have gotten the perks I have paid for. It looks like a promising game and I hope it does well.
drawnacrol, Oct 9, 2014
Our new demo is now available for download. Updates include:
- new locations
- new weapon (flamethrowers)
- improved usability and GUI ('Take All' button, 'fiddle' animations, etc)
- fixed bugs (duplicating traps, animations, reloading weapons, inventory)
- basic vehicle
Demo v. 0.8
Krai Mira, Oct 14, 2014
Gnarles Bronson regular mutant
AtomBomb said: ↑
Doesn't look very text heavy to me...
Gnarles Bronson, Oct 16, 2014
They were able to raise $421.
alec, Nov 13, 2014
oxidize It Wandered In From the Wastes
alec said: ↑
Probably because it was a no-money-back-if-fail campaign, and the fact that it wasn't on Kickstarter.
oxidize, Nov 18, 2014
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The hacking attacks on Equifax and Panera, less than a year apart, were highly publicized events. After all, 146.6 million people were affected by the Equifax breach, and Panera's attack compromised the rewards accounts of more than 37 million customers.
Other than the fact that they were breached by hackers, Equifax and Panera don't have much in common. Equifax might seem like the logical target for data and identity theft because it's one of the country's three major credit bureaus. Panera's breach affected its rewards program.
But what they do have in common is that they were breached through their web applications. Learn how to secure weak points in your application through these four tactics from our full article featured on Business.com.


The Spine VPD 2.0 Vest gives you full back protection with great flexibility and freedom of movement and is tested according to the highest level of the 1621-2 motorcycle standard. The VPD 2.0 system offers a high level of protection with extreme shock absorption as well as a unique capability to adapt its shape to your body. The vest is made offlexible and highly breathable mesh and has height adjustable and removable waistband and two width options, which secures a perfect fit. The back protector is easily removed for washing.


Claude Puel has said Cardiff City have Leicester City's support following the disappearance of record signing Emiliano Sala.
Cardiff's signing was aboard an aircraft that disappeared over the English Channel last Monday, along with pilot David Ibbotson.
Searches for the pair by authorities were unsuccessful, and a private search organised by Sala's family is also yet to discover any sign of the plane or the people onboard.
The search is being funded by a GoFundMe page which has raised more than £290,000 thanks to donations from around the world, including a number of fellow football players.
Cardiff return to action against Arsenal tonight, and it's a situation not too dissimilar to the one Leicester City suffered during October.
The Bluebirds offered a great deal of support to Leicester following the tragic helicopter crash last year that killed owner Vichai Srivaddhanaprabha, welcoming the Foxes with open arms to the Cardiff City Stadium for the first game after the accident.
And that hasn't been forgotten by Puel, who offered Cardiff City Leicester's support as they return to the field this week.
"Of course it's a tragedy, we appreciate a lot the support of their fans," Puel said.
"It's important to be close with them and to support them in this powerful tragedy at the club. It's difficult all the time to have to manage this situation.
"We know this situation in the past. I have thoughts for the families of the player, for the fans, and for the club in France they have had time to know him, he was a nice person and of course, it's a difficult thing to think.
Cardiff return to action on Tuesday evening when they face Arsenal at the Emirates Stadium, and they then face Bournemouth at home.
Bluebirds boss Neil Warnock spoke to the media on Monday and was asked about the similarities between the disappearance of Sala and the helicopter tragedy in October.
"I've not spoken to anyone from Leicester," revealed Warnock.
"But that was another week I'd never experienced anything like that. Two in a short space of time…the emotional effect that had on us, and that wasn't our club.
"The game against Leicester was almost irrelevant and this week has been even worse because I spoke to Emiliano."


ASAP Steel & Pipe offers expanded metal, walkway grating and general-purpose mesh. Each of these resembles a steel grid and can be used within various industries.
The following robust gratings are available: unbanded grating, banded trench grating and standard stair treads. These can be used for industrial walkways and heavy-duty surfaces to ensure a slip-free surface.
General purpose mesh and welded braai grids are also available. It is especially suitable for fencing, caging, and security.


text:
Members of the Equilibrative Nucleoside Transporter (ENT) Family (TC# 2.A.57) are transport proteins that are specific to nucleosides and nucleobases, and are part of the major facilitator superfamily. They generally possess at least 6, typically 10, transmembrane segments (TMSs) and are 300-600 amino acyl residues in length.

Function
ENTs, including those in parasitic protozoa, function in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis and, in humans, are also responsible for the cellular uptake of nucleoside analogues used in the treatment of cancers and viral diseases. By regulating the concentration of adenosine available to cell surface receptors, mammalian ENTs additionally influence physiological processes ranging from cardiovascular activity to neurotransmission.

Human ENTs
In humans ENT are also known as SLC29, a group of plasmalemmal transport proteins which transport nucleoside substrates like adenosine into cells. There are four known human ENTs, designated ENT1, ENT2, ENT3, and ENT4. They are blocked by adenosine reuptake inhibitors like dipyridamole and dilazep, drugs used clinically for their vasodilatory properties.

The best-characterized members of the human Ent family, hENT1 and hENT2, possess similar broad permeant selectivities for purine and pyrimidine nucleosides, but hENT2 also efficiently transports nucleobases. hENT3 has a similar broad permeant selectivity for nucleosides and nucleobases and appears to function in intracellular membranes, including lysosomes. Gemcitabine, an anti-cancer drug, is transported by hENT1 and hENT3. hENT4 is uniquely selective for adenosine, and also transports a variety of organic cations.

Transport Reaction
The generalized transport reaction catalyzed by well characterized ENT family members is:
 Nucleoside (out) → Nucleoside (in)

See also
 Concentrative nucleoside transporter
 Nucleoside transporter

Further reading

References

Protein families
Membrane proteins
Transmembrane proteins
Transmembrane transporters
Transport proteins
Integral membrane proteins

redpajama_set_name: RedPajamaWikipedia


25 years old 5th year medical student at UCL Current qualification: -A levels (As in Chemistry/Bi..
I am currently studying Medicine along with European Studies at the University of Manchester, Englan..
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We all know how challenging customer experience management has become these past few years. Now that most customers use a number of disjointed platforms to interact with companies, contact centres face the challenge of building and maintaining a consistent experience across multiple touch points and channels.
We live in an age where the power is in the consumer's hands. Limited service channels are no longer a problem, and customers can easily find what they need when they need it. This presents a big challenge to many contact centres that find themselves struggling to keep up with the customer's movements.
Despite the rapid rise of IM, email and social media use among today's consumers, voice – the channel that started it all – is still widely used, and its popularity is not showing signs of waning. However, as more platforms emerge, the behaviour of customers will continue to evolve, and centres will need to find more ways to improve the end-to-end customer experience.
Upgrading the CX has proven to be difficult for many contact centres, especially those with an affinity for traditional processes and platforms that border on obsolete. However, this decade has seen a lot of centres that succeed at delivering a consistently excellent service that drives satisfaction and fosters customer loyalty.
It's not just about designing a complete experience. To provide an optimal journey that positively influences CX, managing all types of interactions in every channel used throughout the customer journey is a must. This is what multi-channel contact centre services are all about, and it's one the reasons why we're sought after by many businesses big and small. By unifying all channels, we are able to consistently deliver a satisfactory service across the customers' preferred avenues.
But as the expectations of customers continue to grow, so must the most advanced multi-channel contact centres continue to improve their reach and functionality. As we dissect and study customer interactions to refine our strategies, we must be prepared for obstacles that are bound to pop up every so often, and be open to slight adjustments as well as major improvements.
We can start by evaluating the channels that receive the most attention from customers, before working our way to those that are used the least. Keep in mind that a comprehensive end-to-end strategy must be based not only on the centre's short- and long-term goals, but also on customer histories and insights.
Enhancing the CX is not just about technology and processes; it is much more holistic and requires an understanding of customer psychology.
That said, we must fully understand our customers to solidify all aspects of our people, processes and tools. To deliver an excellent end-to-end experience that drives high ROI in all channels, and ensures customer satisfaction and loyalty, we must capture the voice of the customer (VOC).
To determine the customer's aversions, expectations and needs, equal focus must be placed on all communication channels used throughout the customer journey. When you receive poor ratings from customers, be sure to submit a quick response to alleviate dissatisfaction. Be sure to analyse feedback from interactions as well, to gain valuable insight and context for the CX.
Here's how to leverage the VOC to improve the CX.
Improve how operational, survey and contact data is combined. Analysing how these three elements integrate and contribute to the CX will enable you to identify the impact of existing problems on both agent productivity and customer satisfaction.
Determine what causes customer dissatisfaction. Analyse customer feedback to pinpoint the range of causes of poor satisfaction levels. This will expose weak points and allow you to earmark appropriate resources to address them.
Indeed, the contact centre landscape is changing fast. What was once seen by businesses as a means for cutting costs is now at the forefront of customer engagement, evidently the result of: the rapid rise of new channels of communication; and the changing customer expectations and behaviours influenced by technologies; the evolving role of CX as an influencer and source of business value. We must be proactive in understanding our customers to succeed at building a strategic approach to better influence the end-to-end customer experience.
Rebecca Gunn is a contact centre strategist for My Virtual Workforce. Specialising in customer experience management, she always strives to bring new ideas to the table. She has more than five years of experience with contact centres and has always been passionate about her career. Rebecca spends most of her spare time reading fiction, tinkering with gadgets and occasionally playing video games. You can follow her @itsmerebeccagun.


text:
El CapeFlyer (escrito como CapeFLYER) es un servicio ferroviario regional en Massachusetts que opera entre Boston y Cape Cod e inició sus servicios en 2013. Es operado por el Cape Cod Regional Transit Authority (CCRTA) en colaboración con el Massachusetts Bay Transportation Authority (MBTA) y el Departamento de Transporte de Massachusetts (MassDOT). El servicio opera los fines de semana, iniciando en las tardes de los viernes, y entre Memorial Day y Labor Day.

Durante el 2013, en su primera temporada, el CapeFLYER tuvo un total de 16,586 pasajeros, con servicio extendido durante Labor Day (día del trabajo) al fin de semana de Columbus Day debido a su exitosa apertura. En octubre de 2013, MassDOT anuncio que el servicio regresaría en 2014 y los siguientes años, e incluiría una parada en Wareham empezando en 2014. Se plantea que funcione todos los fines de semana durante todo el año, con servicio tan lejos como Buzzards Bay. El Cape Cod & Hyannis Railroad operaba entre la estación Braintree, un suburbio del sur de Boston, y Cape desde 1984 hasta 1988, pero no extendía el servicio dentro de los límites de Boston.

Véase también
 Sistemas de transporte ferroviario en Estados Unidos

Referencias

Enlaces externos

CapeFLYER Facebook page

Transporte de Boston


FlyerTalk member mare0114 does acknowledge fault when mare0114 Left Designer Jeans in Room but "Not Found" by Fairfax DC, which means the lost $200.00 pair of designer jeans, which were folded up and accidentally left inside one of the drawers of the bedside dresser, will not return to its rightful owner after all.
As other similar stories were being related, FlyerTalk members began wondering why luxury hotels do not proactively call former guests when they find something valuable left behind in a room. Could the answer ultimately be to protect the privacy of the guest?


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To spawn in a chicken jockey, what you actually need to do is spawn a baby zombie, riding a chicken, since a chicken jockey isn't actually a single mob in itself. This command should work in the latest versions (1.8+), otherwise the names may need to be swapped with the equivalent IDs.
For Minecraft: Xbox 360 Edition on the Xbox 360, a GameFAQs message board topic titled "How the hell do you breed chickens?".
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text:
Q: Understanding Theorem 2.28 from Rudin's Real Analysis I don't really understand the wording in this theorem, i.e. what is the hypothesis and what I need to prove.
Theorem 2.28: Let $E$ be a nonempty set of real numbers which is bounded above. Let $y = supE$. Then $y$ is in the closure of $E$. Hence $y$ is in $E$ if $E$ is closed.
I need help understanding what the theorem says and some tips on the proof.

A: The reals have the least upper bound property.
So if $E$ is bounded above then $y = \sup E$ must exist.
Now there are three possibilities.
i) $y \in E$.
ii) $y \not \in E$ but $y$ is kind of close to $E$.
iii) $y$ is a million freaking miles away from $E$ and has nothing to do with $E$.
This theorem says:
iii) is not true.  $y = \sup E$ will always be in the closure of $E$.
Furthermore, if $E$ is closed, then $y = \sup E$ will be in $E$.
Another way of putting this:  $\sup E$ is always a limit point of $E$.
(Hmmm, come to think of it, I wonder we they don't put it that way.)
So
Thereom:  If $E$ is bounded above, then $y= \sup E$ is a limit point of $E$.
Corollary 1: If $E$ is closed and bounded above, then $y = \sup E \in E$.
Corollary 2: If $E$ is bounded above, then $y =\sup B \in \overline {E} = E \cup E'$ (where $E' = \{\text{limit points of }E\}$.
Pf:  $E$ is bounded above so $y= \sup E$ exists.  Let $B_{\epsilon}(y) = \{x\in \mathbb R| d(x,y) < \epsilon\} = (y - \epsilon, y+ \epsilon)$.
$y - \epsilon < y = \sup E$ so $y - \epsilon $ is not an upper bound of $E$.
So there is an $k \in E$ so that $y-\epsilon < k \le y$.  So $k \in B_{\epsilon}(y)$.
So $y$ is a limit point of $E$.
QED
Corollary 1 and 2: follow directly as the definition of limit points and closed sets.
So Theorem 2.28 is basically the theorem and corollaries proven above.

A: The part in blue below isthe hypothesis, and the part in red is what you need to prove.
Theorem 2.28: $\color{blue}{\text{Let } E \text{ be a nonempty set of real numbers which is bounded above. Let }  y = \sup E}.$ $\color{red}{ \text{Then } y \text{ is in the closure of }E. \text{ Hence } y \text{ is in }E\text{ if }E \text{ is closed.}}$
In a theorem, the word "let", "suppose", "assume" let us introduce hypothesis.
You are given a non-empty set  of real numbers, $E$, and it is bounded above. That is $E \neq \emptyset$  and we can find an integer $M$ such that $\forall x \in E, x < M$.
Let $y = \sup E$. You have to prove that $y$ is in the closure of $E$, it means you have to show that $y$ is in $E$ or $y$ is a limit point of $E$. In other words, if $y$ is not in $E$, show that $y$ must be a limit point of $E$. Suppose not $\ldots$, try to use the definition of supremum to get a contradiction.

A: HINT:
$y=\sup E$ is the smallest upper bound of $E$. So for every $y'< y$, $y'$ is not an upper bound of $E$. So, there exists $e \in (y',y]$.  That shows that every open interval around $y$ contains points of $E$, and therefore $y \in \bar E$.

A: $s=\sup E$ is either in $E$ or a limit point of $E$.  Proof:  Assume $\sup E$ is not in $E$.  Then by definition of $\sup$, there is no  $t < s$ such that $\forall e\in E:t \ge e$.  That implies for every $\epsilon > 0$ there is some "test" element $u\in E$ that is greater than $s -\epsilon$; otherwise,  $s-\epsilon$  is an upper bound of $E$ which is less than $\sup E$, contradicting the definition. Lets call such an element $\tau(\epsilon)$.
Now for some given $\epsilon$ and corresponding "test" element $u > s-\epsilon$, consider the sequence $u_0 = u, u_1 = \tau((s-u_0)/2), \cdots u_k = \tau((s-u_{k-1})/2)$.  That sequence demonstrates that $s$ is a limit point of $E$.
Therefore $s$ is in the closure of $E$, and by definition of a closed set, $s$ is in $E$ if $E$ is closed.


text:
Q: create a login page in vb.net by c# & mysql but it shows error message connection must be valid and open private void admin_submit_button_Click(object sender, EventArgs e)
        {
           try
           {
               string myConnection = "datasource= localhost;port=3306;username=root;password=root";
           MySqlConnection myConn = new MySqlConnection(myConnection);

           MySqlCommand SelectCommand = new MySqlCommand("select * from mws.login_info where login_id='" + this.admin_id_textbox + "'and login_password1='" + this.admin_password_textbox1 + "' and login_password2='" + this.admin_password_textbox2 + "'");
           MySqlDataReader myReader;
           myConn.Open();
           myReader = SelectCommand.ExecuteReader();
           int count = 0;
           while (myReader.Read())
           {
               count = count + 1;
           }
           if (count == 1)
           {
               MessageBox.Show("username and password is correct");
           }
           else
               MessageBox.Show("username and password not correct");
           myConn.Close();
       }
        catch(Exception ex)
       {
           MessageBox.Show(ex.Message);

        }
    }
}

}

A: You have not associated the command with the connection. You code lacks of the following line
SelectCommand.Connection = myConn ;

Said that, imagine that I write in your admin_id_textbox the following text
' OR login_id like '%' --

what happen to your checks for the correct login?
It is called Sql Injection and it is a very dangerous situation for every kind of database access.
Use always a parameterized query to build sql commands, in particular when part of your command is built using user input text
private void admin_submit_button_Click(object sender, EventArgs e)
{
    try
    {
       string cmdText = @"select * from mws.login_info
                         where login_id=@id and login_password1=@pwd
                         and login_password2=@pwd2";
       string myConnection = "datasource= localhost;port=3306;username=root;password=root";
       using(MySqlConnection myConn = new MySqlConnection(myConnection))
       using(MySqlCommand SelectCommand = new MySqlCommand(cmdText, myConnection))
       {
           myConn.Open();
           SelectCommand.Parameters.AddWithValue("@id", this.admin_id_textbox);
           SelectCommand.Parameters.AddWithValue("@pwd",this.admin_password_textbox1);
           SelectCommand.Parameters.AddWithValue("@pwd2",this.admin_password_textbox2);
           using(MySqlDataReader myReader = SelectCommand.ExecuteReader())
           {
               if(myReader.HasRows)
                   MessageBox.Show("username and password is correct");
               else
                    MessageBox.Show("username and password not correct");
           }
       }
    }
    catch(Exception ex)
    {
       MessageBox.Show(ex.Message);
    }


It certainly is a rainy start to 2017, isn't it?
It's a wonderful opportunity to relax, focus our energies within.
I invite you to simply listen to the rains, reminding us of not only nature's resiliency, but our own.
This Sunday, very much related to this theme of living waters, we will be renewing our baptismal vows. I will have a strange and beautiful story to share with you about a baptismal experience I had in Point Reyes this past week.
I am sharing with you some photos from this trip, and a poem about the rains by Mary Oliver.
May the rains renew your souls this week.


The second most popular benefit after healthcare. While the complexities of this marketplace do not equal that of healthcare, we know the health of your employees' teeth is very important to their overall health. We will not treat this benefit as an afterthought, giving it the focused attention it deserves as one of your first levels of employee benefits.


text:
by Michael Misiak
Worry Moves On
by Liz Haske
WhaleSpirit
by Daniel Thomas
Roots and Tendrils
by Heidi Dellaire
by Ronald L. Ruiz
Pressing on Toward Maturity
by Joey A. Perry, Sr.
by AJ Rice
No Marriages in Heaven
Blue Skies of Leo Lejon
by Dawn Bogart
Short Stories IV: Fantasy & Sci-Fi
by Rich DiSilvio
Chasing the Omega
by Jessica Edwards
A Better Human
by George J. Bradley
Escaping Midnight
by Andrew Schrader
Wild Hare
by Laura Koerber
Contact Author - Laura Koerber
Laura is a writer and artist and lives with her husband and family of dogs on an island in Puget Sound. Her first book, The Dog Thief and Other Stories, was listed in Kirkus Review as one of the One Hundred Best Indy Publications of 2015. Since then, she has written two more novels.
Her second novel, Limbo, is a fantasy about a dead teenager who decides to throw a neighborhood block party for her small corner of the afterlife. Publisher's Weekly described Limbo as "a slow, captivating exploration of life, death, and the place of kindness and forgiveness in the salvation of the spirit."
Eclipse Dancer, her third novel, is the first in a planned quartet--of which WIld Hare is the second-- featuring interactions between nature spirits and ordinary life. The nature spirits are loosely based on a combination of Native American spirituality and the fairies of Northern European tradition. A winner of an honorable mention in the 2019 Readers' Views Literary contest, Eclipse Dancer earned this praise from reviewer S.L. Hoyte: "Combining elements of fantasy with hard-core human issues, many relevant in today's world, Koerber takes the reader on a magical journey as down-to-earth as it is out-of-this-world..,The writing is descriptive and artistic, without being flowery or overdone, and leaving just enough room to incorporate snippets of one's own imagination. Some things are just not taught and Koerber's writing is one of those things–she has a gift."
Reviewed by Grant Leishman for Readers' Favorite
Wild Hare was certainly something different in the reading genre from my perspective. Author Laura Koerber has brought us a tale of fairies and other magical creatures but they are far removed from the usual fairies and fae of fantasy novels. These fairies and half-fairies are, it seems, just normal characters trying to survive in a world gone crazy. Like the animals, the fairies have seen their world and their habitat shrink over the generations due to man's incessant demands on his environment. Consequently, it appears they are indeed a dying breed struggling for survival. Living at a run-down resort out near Bear Lake, Bob gets by on a day-to-day basis with a bit of petty thievery, using his somewhat limited fairy skills and some odd-job work with his best mate Arne. Always wary about the militia who now runs the police force, Bob and his friends lament the destruction of their environment and the loss of personal freedoms in their country. It is 2032 and the all-seeing, all-controlling Government has everyone at their mercy but Bob's not so sure that he and his fairy friends can take much more. Perhaps it is time to strike back.
I really enjoyed Wild Hare, it was something different. I loved the idea of red-neck, southern characters coupled with the abilities of supernatural creatures such as fairies. Bob was a fascinating character. Outwardly he cared little about the goings-on around him and sought solace in his limited slice of freedom at his cabin, in the forest and by the lake, but deep down a rebellion was stirring inside him. To me, as a reader, Bob epitomized the concept of the individual who feels he can do nothing on his own to change the system, so why even try. It takes an epiphany of a little old lady and his best friend's arrest to get him riled up enough to take action. Bob was complex, yet simple and that's what I liked the most about him. The opportunity to learn something of the Native American legends and culture was a real bonus in this story. I particularly appreciated the idea that fairies and their ilk revealed themselves to the Native Americans and lived in harmony with them, but understood that wasn't possible with today's modern humanity – a definite indictment on our society, of course. Beautifully written with a descriptive focus and limited dialogue, the story eloquently tells of the pain and angst as the fairies watch their world being destroyed by man's greed, seemingly unable to stem the tide. I can highly recommend this book for anyone looking for something just a little bit different.
Wild Hare is a fast paced work of apocalyptic and dystopian fiction penned by author Laura Koerber. Combining such varied concepts as fantasy and magic with climate change and political domination is no mean feat, but the plot of this adventurous tale does just that. The central character is Bobby Fallon, an acerbic petty criminal who happens to be part forest fairy. Attached to the Wild Hare clan and guarding a small patch of turf, Bobby negotiates the problems of the real world as everything slowly turns to chaos around him. Poking fun at the exacerbation of conservativism, Bobby's daily struggles are leading him to the end of the world, and he knows it.
Author Laura Koerber has created a truly unusual work of fiction, painting a portrait of a more realistic apocalypse that everyone can actually see coming. Charged with in-jokes about the current state of politics in the USA, the themes are gently wound into a humorous and genuinely compelling tale of ordinary people trying to get on with their lives. Despite the disaster around him and some of Bobby's more questionable actions, it's clear that he is written with affection, and grows on you as a fashionable anti-hero rebelling against every plot twist that hits him. The atmosphere is well maintained from scene to scene, dwelling in that strange place where you can't believe that something is true, yet you know it really is. Overall, Wild Hare is masterful in its blend of satire and dystopian adventure, with a magical twist that offsets the reality of the plot beautifully.
Jessica Barbosa
Wild Hare by Laura Koerber focuses on the point of view of a half hare fairy, half human named Bob Fallon. His life is a cycle, a routine of sorts. He helps Arne, hangs out with Sally, Charlie, and Danni, waits for the next fairy dance… feeds, fornicates, and fights. Overall, Bob's personal life is as good as it is going to get in Secret Lake and Bear Lake. Still, Bob burns inside as he looks around at the dying forests and greedy insatiable humans. He knows that his life might be 'okay' right now, but with the way things were going, it probably wouldn't last. Even though he is a fairy that could hypnotize people sometimes, the power he and the other native spirits have is nothing compared to human stupidity and greed. Money is the most powerful magic of all, but as things go from bad to worse, he finds he just can't keep standing by to watch the greedy people win.
Laura Koerber's characters are so innately human in their actions, thoughts, and words that I was left stunned. The characterization of Bob is amazing as someone who is vindictive and angry at the state of the world, at the state of the poor, but had the power to actually do something about it, even giving in to pettiness just to get back at someone (anyone) who is directly or indirectly the cause of how the horrible the world has become. When I place myself in Bob's shoes, and although I do not agree with some of his actions, I 'understood' and sympathized with his reasons for doing them. Bob is angry with himself for doing nothing, with the humans for hurting the forests, the lake, the world. He had a right to that anger, injustice constantly surrounded him and he felt helpless, useless. But that anger led him to do the wrong things and his actions had consequences.
Koerber emphasized these key points skillfully in Wild Hare, with well thought out and quotable lines like, "Is this how bad people do bad things—by forgiving themselves?" and "When you fight a violent and mean enemy, it's difficult not to become violent and mean yourself." I am impressed with how Koerber weaved unforgettable moral lessons through the tough tangles of the problems their society faced in Wild Hare. The content is intense and, to me, there is never a dull moment with every turn of the page. This was truly a one of a kind story. Thank you to the author for the unforgettable reading experience.


Due to inflammation in the bronchi, great quantities of mucus are concealed and expelled as phlegm. This phlegm is humid, semi-fluid and may even be purulent.
The patient bears from fever, experiences some obscurity in breathing, and has a cough.
Other indications are hoarseness, pain in the chest and loss of appetite.
A vital cause of bronchitis is smoking. Extreme smoking irritates the bronchial tubes and lowers their resistance, so that they become susceptible to germs breathed in from the environment.
Other causes are livelihood or operational in a stuffy atmosphere, use of drugs to restrain earlier diseases, and hereditary causes.
Changes in weather and atmosphere hasten the start of the disease.
A mixture of one teaspoon of sesame seeds, mixed with a teaspoon of linseed, a pinch of common salt, and a teaspoon of honey, can be given once at night with helpful effects in bronchitis. Half a teaspoon of dry seeds crushed into powder should be given mixed with two tablespoons of water, two times every day. Alternately, a decoction of half a teaspoon of the same must be taken two times every day.
An emulsion of almonds is helpful in bronchial sickness, including bronchitis. It is made by making a powder of seven most important parts of almonds and mixing the powdered kernels in a cup of orange or lemon juice. This mixture may be taken once every day at night.
Chicory or endive is one more effectual home remedy for bronchitis. The powder of the dry root of this herb must be given in dosage of half a teaspoon mixed with one teaspoonful of honey three times daily. It is a very helpful expectorant in chronic bronchitis.


text:
Q: Why do I get "Connection was refused by the server" when using Thunder Client on VS Code? I'm using Thunder Client on Visual Studio Code, and tried making a request to "localhost:3000".
It gave me an error

Connection was refused by the server

Any fix to this?

A: You are facing this problem because of backend you juts have to start your backend and also make sure you have install body-parser

A: Using SvelteKit, VSCode and Thunder Client
Example that didn't work for me:
localhost:5173/api/posts
Solved by using
[::1]:5173/api/posts

A: Please use your IP address instead of localhost: ipaddress:port.
Then, it might work. Eg. 192.168.0.1:3000
For more information see our support page comment
https://github.com/rangav/thunder-client-support/issues/251#issuecomment-874439967

But instead of using localhost:9000 I did use the actual IP set for the computer… 198.168.0.189:9000 for example, then it works.

A: *

*if you are using WSL on Windows use [::1] instead of localhost in the address bar. Example [::1]:3000/api/v1 .

*Another option is to use the PowerShell instead of the WSL terminal.

*You can also move your project directory to the Linux file system (~/home)

A: Using Django here and sending request to
127.0.0.1:8000/

instead of
localhost:8000/

works