VERSATILITY: Each topic may be customized for your specific program format and audience whether it is a keynote address, a two-hour general session, or a full-day seminar.
ADDED VALUE: Invite Dr. Haymon to present multiple presentations for your conference with no additional investment. For example, have her present a keynote address plus a breakout session or spouse program.
VIDEO RECORD: A video recording of Dr. Haymon's presentation can also be made available for future use.
"Fantastic!! Incredible!! Unbelievable!! Phenomenal!! I could go on and on with adjectives to describe Dr. Haymon's marvelous lecture. Dr. Haymon is the most effective speaker I have ever heard."
—Shari Taylor, Educator Coordinator, HealthSouth Rehabilitation Hospital, Dothan, AL.
"Dr. Haymon's ability to have her audience wiping tears from their eyes and in the next breath have them laughing was just amazing!"
—JoAnne Beasley, RN, Asst. Director of Nursing, Pelham Parkway Nursing Home, Pelham, GA.
"Thank you for participating in our 39th. Annual Conference in Savannah. Never in the history of our 39 years have we received such high evaluations for a speaker."
—Jayne Hendley, President of Council on Auxiliaries/Volunteers of the Georgia Hospital Association.
Dr. Haymon's research on Work Addiction has been cited in more than twenty major newspapers in the United States and Canada. In related seminars, Dr. Haymon addresses the toll work addiction takes on its' victims as well as the negative impact it has on family members, co-workers and productivity.
Dr. Haymon's presentations are a must for personal and professional caregivers (physicians, physician assistants, RNs, LPNs, CNPs, CNAs); management, staff and volunteers working in hospitals and elder care facilities, psychologists, social workers, certified professional counselors; estate and financial planners; anyone employed in the insurance industry; anyone who will ever be a caregiver, or may ever need a caregiver; and anyone who ever plans to retire.
Dr. Haymon's practical advice and emotional support empowers individuals to overcome their greatest challenges. In addition to feeling empowered, participants leave feeling inspired, as well as informed. Dr. Haymon offers Keynote Addresses and Presentations throughout the United States and Canada. Presentations are customized to fit your time frame, as well as your particular audience, and are available in both Keynote and Conference formats.
for your organization or community.
Dr. Sandra W. Haymon, America's #1 Caregiving Expert, licensed psychologist, author, and International speaker is internationally recognized as an expert in the fields of caregiving, eldercare, retirement, and work addiction. Utilizing her own personal and professional experiences, she combines her energy, wit, compassion, and expertise to educate, motivate, empower, and entertain her audiences.
Dr. Haymon draws from her popular books, Baby Boomers-Sandwiched Between Retirement & Caregiving, and My Turn: Caring for Aging Parents & Other Elderly Loved Ones-A Daughter's Perspective, to guide family and professional caregivers thru the maze of physical, practical, emotional, and spiritual issues of caregiving. She explores options and offers solutions to challenges associated with caregiving-for the caregiver, as well as the person being cared for. She also teaches participants how to decode the 'Alphabet Soup' (acronyms and jargon) used by medical and legal professionals.
Dr. Haymon's presentations are a must for family and professional caregivers; all healthcare providers (physicians, physician assistants, RNs, LPNs, CNPs, CNAs); management, staff and volunteers working in hospitals, nursing homes, memory impaired facilities, personal care homes, and assisted living settings; psychologists, social workers, certified professional counselors; estate and financial planners; anyone employed in the insurance industry; anyone who is presently a caregiver, will ever be a caregiver, or may ever need a caregiver; and anyone who ever plans to retire.


text:
Project Innovation
Working to help conserve the earth's wildlife and wild places has involved raising awareness around crucial conservation issues, from the impacts of urbanisation on wildlife, to wilderness protection, rhino poaching and threats facing the world's cetaceans.
With my husband Noel Ashton, we have launched many programmes that shine a spotlight on these issues, with the vision of changing people's perceptions not only around how we relate to and impact on the natural world, but how the natural world supports our own lives.
Each project involves :
concept and origination
securing programme partners and sponsorships
creation of copy / promotional materials
implementation (including printing / installations)
managing media and launch events
Programmes have included –
Sacred Ocean anti-whaling campaign with Archbishop Desmond Tutu. The campaign message went around the world through Reuters and many thousands of people joined the campaign. Programme partners included the Two Oceans Aquarium and IFAW Southern Africa.
Windows on the Ocean awareness campaign in partnership with The De Beers Group and IFAW. Launched in the Two Oceans Aquarium and then the Whale Museum in Hermanus. Seen by over a million people.
Reconnecting with Nature in partnership with the SA National Biodiversity Institute. These displays were installed in the nine National Botanical Gardens throughout South Africa. Focusing on our connections to the natural world and seen by many thousands of visitors to the national botanical gardens. With sponsorship from the Hans Hoheisen Trust.
Mapungbubwe Revisited campaign with WWF South Africa. Through various special events, we raised over ZAR 550 000.00 for WWF's rhino conservation work.
Wild Neighbours in partnership with The Humane Society US, IFAW, De Beers Marine and Woolworths SA. Various awareness materials have been created and distributed over the years, including booklets, awareness flyers and outdoor signboards which were installed in 12 nature reserves and 3 private estates around Cape Town.
Please be in touch if you would like to chat about working together.

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: Как правильно сравнить дату C# Ребята подскажите как правильно сравнить дату?
у меня есть запрос в бд, там отбирает строки и возвращает результат, как коллекцию обьекта по шаблону:
cmd.ExecObjects(new
        {
            Name = string.Empty,
            Date = DateTime.MinValue,
        });

Дальше там идет построение таблицы
sb.AppendFormat("Имя:{0}, дата {1}
", row.Name, Date.ToString("dd.MM.yyyy"));

в результате на екране у меня выдает дату 01.01.0001. поэтому нужна доп проверка. Как ее правильно сделать? Как правильно представить дату(сейчас ToString("dd.MM.yyyy")?

A: Вот как я реализовывал нахождение разницы во времени через DateTime

dataInfo- объект полученный из БД

В нем dataInfo.Time - время в формате "dd.MM.yyyy hh:MM:ss:mm"
 DateTime enteredDate = DateTime.Parse(dataInfo.Time);
                var x = DateTime.Now;
                var time = (enteredDate - x).Duration();

а уже из time конкретно что нужно: годы, месяца, дни, часы.....

A:
Как правильно представить дату(сейчас ToString("dd.MM.yyyy")?

string text = dateTime.ToString("MM/dd/yyyy HH:mm:ss.fff",
                            CultureInfo.InvariantCulture);

или добавив одинарные кавычки побоказ слэшей:
string text = dateTime.ToString("MM'/'dd'/'yyyy HH':'mm':'ss.fff");

*

*MM - Месяц с предшествующим нулем

*M - просто месяц без нулей

*dd - с ну нулем

*d - без нулей

*yyyy - 4-символьный год

*yy - 2-хсимвольный год

*HH - 24часовый формат часов с предшествующим нулем

*H - 24часовый формат без предшествующим нуля

*hh - 12часовый формат часов с предшествующим нулем

*h - 12часовый формат часов без нуля

*mm - минут с предшествующим нулем

*m - без нуля

*ss - секунды с предшествующим нулем

*s - секунды без предшествующего нуля.

А на тему сравнения....
Т.к. обьект ДатыВремени хранит и дату и время, а нужно сравнивать только даты... То нужно вытягивать именно дату из DateTime :
DateTime dt1 = DateTime.Now;
DateTime dt2 = DateTime.Now.AddHours(3);

if( dt1.Date == dt2.Date)//смотри, я работаю только с датами!
{
    //some action
}

redpajama_set_name: RedPajamaStackExchange


text:
Voice of OC - Orange County's nonprofit newsroom
Voice of OC (https://voiceofoc.org/2012/05/)
Gerry Serrano
John Phillip Sousa
San Clemente Homeless Camp
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State Denies Great Park Bid to Keep $1.4 Billion in Tax Dollars
The state's decision further clouds the future of what was billed as a rival to Balboa Park in San Diego and Central Park in New York.
A Supervisor's Take on Proclamations in Orange County
By NORBERTO SANTANA JR. | May 31, 2012
After a dust-up last week over Harvey Milk Day at the Board of Supervisors meeting, Supervisor Shawn Nelson said the county needs to revise policies on proclamations.
Community Editorial: An Activist's Take on the Cadiz Water Project
Community Editorials
By DEBBIE COOK | May 31, 2012
Attorney asserts that a host of chummy relationships fuel the bid by an OC water district to grab water from a small desert community.
Costa Mesa Might Rethink Hiring Former Bell Auditors
By NICK GERDA | May 30, 2012
Councilman plans to "look at options" after state accuses the firm of "repeated acts of negligence" when auditing Bell's finances.
Artists Issue Ultimatum to Church Buying Santora Building
Countywide
By ADAM ELMAHREK | May 30, 2012
Artists say Newsong church leaders have three days to make a deal to protect artists in the building if they want to avoid public protests.
Community Editorial: Trying to Let Go in a Special-Interest Era
Board of Supervisors Chairman John Moorlach discusses the politics of budget balancing.
Several cities examine proposed budgets, and Anaheim decides whether to purchase an airplane for the Police Department.
Resident Challenges Pace of Updating Newport's Charter
Jim Mosher says the city is skirting a state law designed to ensure a fair appointment process.
Homelessness Panel Urges Supervisors to Adopt Laura's Law
The law, a big issue in the aftermath of the Kelly Thomas beating, would allow court-supervised outpatient treatment of mentally ill adults.
Artists Seek Removal of Councilman From Santora Panel
They say David Benavides' attendance at Newsong Church should bar him from serving on the committee examining the church's purchase of the downtown Santa Ana building.
In La Palma tonight, officials will talk about allowing an Adult Day Health Care facility to run on weekdays out of the United Methodist Church, at Walker Street and La Palma Avenue. Council meets at 7 p.m. Background: https://t.co/Fv8nILVXO1 Meeting: https://t.co/FcKxqetwR1
In Brea tonight, officials will consider a redesign to the civic center's third floor, which may cost up to $495,000. The redesign would replace old furniture and add improvements to office cubicles. Background: https://t.co/pKLPfI9au1 Meeting: https://t.co/wJwmigvF9I
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Wolf: Return-to-Field is Better for Cats, Shelters, and Communities
Peter Wolf representing Best Friends Animal Society, one of the largest animal welfare organizations in the U.S. and a leader in the development and operation of community cat programs, explains the benefits of the Return-to-Field program compared to the "traditional" approach for managing feline intake.
Kriz: Homeless Deaths on the Decline, Slightly
Fr. Dennis Kriz, Pastor at St. Philip Benizi Catholic Church in Fullerton, writes that it is worth noting that the rate of death among those who without a fixed abode has gone down in June.
Santana: The Pesky Public
Keeping the public out of the loop has become an extreme sport for our elected class as well as the greatest threat to our democracy. In recent times, we've seen efforts here in Orange County to illegally restrict public comment, destroy public documents, squash dissenting council members, delay release of police misconduct records along with the murky process of monitoring state harassment investigations or changing federal regulations.
Logan: OC Animal Care Wrong to Return Sheltered Cats Back Into Neighborhoods
Sharon Logan, founder of Paw Protectors Rescue, questions OC Animal Care over its controversial practice of returning sheltered cats back into neighborhoods.
Inside the Newsroom »
Voice of OC Reporter Nick Gerda Honored as Online Journalist of the Year in Greater Los Angeles
County reporter Nick Gerda was given the honor Sunday evening for his work in 2018 by the Los Angeles Press Club and Publisher Norberto Santana, Jr. won the honor the previous year.
City of Orange Special Election Cancelled as Part of Settlement Agreement Related to Voting Rights Case
Placentia Leads Settlement Agreement and Partners on First of its Kind Regional Homelessness Plan
County Approves a Plan for John Wayne Airport General Aviation Improvement Program
Voice of OC
Support & Partnerships
Impact & Honors
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text:
AK and SYK kinases ameliorates chronic and destructive arthritis
Mouse monoclonal to CD54.CT12 reacts withCD54
Background: Sickle cell disease causes significant morbidity and mortality and affects
Posted on June 17, 2019 9:22 am by Ann Ward
Background: Sickle cell disease causes significant morbidity and mortality and affects the economic and healthcare status of many countries. gene therapy. Bottom line: These illustrations demonstrate the way the current understanding of sickle cell disease pathophysiology and treatment strategies intersect. Although curiosity about sickle cell analysis has blossomed, a lot more scientific trials have to be initiated and put through more strenuous evaluation and evaluation than have already been utilized in the past. solid course="kwd-title" Keywords: em AnemiaCsickle cell /em , em hereditary therapy /em , em hydroxyurea /em , em oxidative tension /em , em poloxamer /em , em stem cell transplantation /em Launch In 1910, sickle cell disease burst onto the Traditional western medical scene being a unusual or, as Herrick termed it, a fresh, unidentified disease.1 Doctors were intrigued with the sickled appearance from the crimson cells within this disorder, and case reviews and analytical documents detailing the clinical top features of this disorder seemed to more often than not involve folks Torisel distributor of color.2-6 The condition became referred to as a dark disease then.6-8 Not until 1949, however, was the Mouse monoclonal to CD54.CT12 reacts withCD54, the 90 kDa intercellular adhesion molecule-1 (ICAM-1). CD54 is expressed at high levels on activated endothelial cells and at moderate levels on activated T lymphocytes, activated B lymphocytes and monocytes. ATL, and some solid tumor cells, also express CD54 rather strongly. CD54 is inducible on epithelial, fibroblastic and endothelial cells and is enhanced by cytokines such as TNF, IL-1 and IFN-g. CD54 acts as a receptor for Rhinovirus or RBCs infected with malarial parasite. CD11a/CD18 or CD11b/CD18 bind to CD54, resulting in an immune reaction and subsequent inflammation molecular character of sickle cell uncovered.9 In 1958, Ingram uncovered the genetic basis of the condition and confirmed that the condition comes from the substitution of the valine for glutamic acid on the sixth amino acid position from the hemoglobin beta chain.10 This amino acidity substitution, now regarded as the consequence of an individual stage mutation from the hemoglobin gene, generates profound changes in the behavior and conformation of the hemoglobin molecule in individuals affected by the disease.11 In 1927, Hahn and Gillespie experienced reported within the mechanism of sickle formation, observing the sickle hemoglobin in its deoxygenated state assumed the characteristic shape, the sickle, that gives the disorder its name.12 Cells containing deoxygenated hemoglobin not only formed this rigid shape but also were dehydrated,13 had abnormal cell surface and distinct migratory characteristics, were sticky and prone to adhesion, and had abnormal rheologic properties.14,15 Clinically, not only did patients with sickle cell disease experience repeated painful episodes (crises), but because of recurrent episodes of vaso-occlusion, they ultimately suffered chronic organ damage. Physicians mentioned a paucity of individuals who survived into their adult years.6 Sickle cell disease, probably one of the most common inherited diseases worldwide, is now understood to be a disorder of global importance and economic as well as clinical significance. Those affected by the disease live in areas of sub-Saharan Torisel distributor Africa, the Middle East, India, the Caribbean, South and Central America, some countries along the Mediterranean Sea, as well as in the United States and Europe.16 The disease has, at times, through forced and unforced migration, been introduced to areas in which it was not endemic.17 In the United States, 80,000-100,000 individuals are affected by the disorder; worldwide, more than 300,000 children are estimated to be given birth to yearly with sickle cell disease. 18-20 This quantity includes approximately 3, 000 children given birth to with the disease each 12 months in the United States.18 Since the 1980s, novel strategies for the treating sickle cell disease possess included the introduction of penicillin prophylaxis for kids with sickle cell,21 the organization of newborn testing programs,22 and the usage of transcranial Doppler verification for recognition of cerebral heart stroke and vasculopathy avoidance.23 Hematologists possess long recognized the necessity for better remedies of sickle cell. Optimally, cure approach was required that didn't just address discomfort or treat and stop sequelae of the condition (eg, susceptibility to an infection from asplenia). That which was required instead was cure approach that proved helpful by undercutting the pathophysiology of the condition. Research initiatives previously focused on understanding the pathogenesis of the condition instead of on providing better comfort for the sufferers getting the Torisel distributor disorder. Improvement in coming to satisfactory treatment of people with sickle cell provides often appeared to be a gradual, halting procedure. Also, financing for analysis of sickle cell disease lagged behind that of various other genetic illnesses, fueling a suspicion that racial bias avoided significant outlays of moneys for research from the disorder.24-27 The innovations enumerated above did bring about stepwise improvements in survival, therefore the median life span for all those with homozygous disease is currently in to the fourth and fifth decades.28 Beyond hydroxyurea, which was introduced into clinical practice in the 1980s for adults,29,30 few new medicines have been investigated or placed on the market for the treatment of Torisel distributor the disorder until recently. This review investigates areas of.
activated B lymphocytes and monocytes. ATL
also express CD54 rather strongly. CD54 is inducible on epithelial
and some solid tumor cells
fibroblastic and endothelial cells and is enhanced by cytokines such as TNF
IL-1 and IFN-g. CD54 acts as a receptor for Rhinovirus or RBCs infected with malarial parasite. CD11a/CD18 or CD11b/CD18 bind to CD54
resulting in an immune reaction and subsequent inflammation.
the 90 kDa intercellular adhesion molecule-1 ICAM-1). CD54 is expressed at high levels on activated endothelial cells and at moderate levels on activated T lymphocytes
Torisel distributor
Hydantoin racemase from was expressed in sp. (ATG) at position 1
Posted on April 1, 2017 11:38 am by Ann Ward
Hydantoin racemase from was expressed in sp. (ATG) at position 1 of the hydantoin racemase gene instead of the original valine (GTG). Additionally in order to avoid the creation of a fusion protein between the hydantoin racemase gene and the N-terminal end of the β-galactosidase gene present in the pBluescript II SK(+) plasmid (pBSK; Stratagene Cloning Systems) a TGA codon was included upstream of the ribosome binding site sequence and the beginning of the gene in the SmRac5 primer. The SmXaRac3 primer included the factor Xa recognition sequence (Ile-Glu-Gly-Arg) and a polyhistidine LY 2874455 tag (His6 tag) before the stop codon. The hydantoin racemase LY 2874455 showed significant amino acid sequence identity with hydantoin racemase amino acid LY 2874455 sequences from different sources in GenBank (Fig. ?(Fig.1).1). Moreover two cysteine residues at positions 76 and 181 which are probably involved in the catalytic center of the protein (21) were highly conserved within the studied hydantoin racemases. The highest sequence identity was presented between hydantoin racemase and C58. Surprisingly this identity was almost twofold higher than that shown previously between LY 2874455 sp. strain IP I-67 and C58 which would be expected to show higher sequence identity as they belong to the same genus. FIG. 1. Multiple alignment of the amino acid Mouse monoclonal to CD54.CT12 reacts withCD54, the 90 kDa intercellular adhesion molecule-1 (ICAM-1). CD54 is expressed at high levels on activated endothelial cells and at moderate levels on activated T lymphocytes, activated B lymphocytes and monocytes. ATL, and some solid tumor cells, also express CD54 rather strongly. CD54 is inducible on epithelial, fibroblastic and endothelial cells and is enhanced by cytokines such as TNF, IL-1 and IFN-g. CD54 acts as a receptor for Rhinovirus or RBCs infected with malarial parasite. CD11a/CD18 or CD11b/CD18 bind to CD54, resulting in an immune reaction and subsequent inflammation. sequences of hydantoin racemases. Shown are the sequences for hydantoin racemase from (SmeHyuA) GenBank accession no. "type":"entrez-nucleotide" attrs :"text":"AY393697″ term_id :"37574379″ term_text :"AY393697″ … LY 2874455 Functional expression and purification of hydantoin racemase. The hydantoin racemase gene was functionally expressed in BL21 and its activity was assessed by chiral high-performance liquid chromatography as previously referred to for C58 hydantoin racemase (8). A one-step purification treatment from the recombinant hydantoin racemase fused towards the His6 label was utilized by using immobilized cobalt affinity chromatography accompanied by proteolytic digestive function with element Xa. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) evaluation indicated how the purified enzyme was a lot more than 95% genuine after elution from the affinity column (Fig. ?(Fig.2).2). Particular activity was determined for the purified enzyme. In 0.1 M Tris buffer (pH 8.5) the enzyme was steady at 4°C for 10 weeks; in the same buffer with 20% glycerol the purified enzyme could possibly be kept at ?20°C for a lot more than three months without noticeable lack of activity. The purified enzyme was energetic after 10 freeze-thawing cycles. FIG. 2. SDS-PAGE evaluation of every purification stage of hydantoin racemase from BL21 harboring the pSER27 plasmid. Street 1 BL21 including pBSK plasmid without put in; lanes 2 and 3 supernatant and pellet from the resuspended crude draw out … Molecular subunit and mass structure of hydantoin racemase. The obvious molecular mass from the purified enzyme subunit (31 kDa) after launching on SDS-PAGE (Fig. ?(Fig.2)2) was nearly the same as those of sp. stress NS671 (32 kDa) DSM 3747 (31 kDa) and C58 (31 kDa) (8 20 21 In every cases these obvious molecular masses had been higher than those determined through the amino acidity series (25 to 27 kDa). The comparative molecular mass from the hydantoin racemase (100 kDa) was assessed by size exclusion chromatography on the Superdex 200 HR column. As a result the hydantoin racemase presents the same tetrameric framework as that previously referred to for C58 (8) as the sp. stress NS671 hydantoin racemase enzyme continues to be referred to as hexameric (20) as well as the DSM 3747 hydantoin racemase enzyme continues to be categorized as hexameric heptameric or octameric (21). Physical effects and characterization of temperature and metallic ions about hydantoin racemase activity. An ideal was showed from the hydantoin racemase reactivity at pH 8.5 when examined in 100 mM phosphate Tris or glycine-NaOH buffer at several pHs. This pH worth was similar compared to that previously referred to for DSM 3747 but was greater than that of C58 (pH 7.5) and less than that of sp. stress NS671 (pH 9.5). With sp Together. stress NS671 hydantoin racemase demonstrated the lowest ideal temp reactions (45°C) whereas DSM 3747 and C58 hydantoin racemases show optimum activity at 55 and 60°C respectively. When.
LY 2874455
Orphan 7-Transmembrane Receptors
Orphan G-Protein-Coupled Receptors
Orphan GPCRs
Other Calcium Channels
Other Oxygenases/Oxidases
Other RTKs
OXE Receptors
Oxytocin Receptors
Supplementary MaterialsImage_1
Inflammatory response is usually important for the host defense against diarrheagenic and plays a part in the pathogenesis of the condition but there isn't a comparative research among different diarrheagenic pathotypes
Mesenchymal stem cells (MSC) are multipotent stromal cells using the potential to differentiate into many cell types
Supplementary Materials1
Pluripotent stem cells, defined by an unlimited self-renewal capacity and an undifferentiated state, are greatest typified by embryonic stem cells
Adonitol AMG-073 HCl AT7519 BMS-265246 BMS-707035 Bosutinib BTZ043 Calcipotriol Calcitetrol Cdx1 CUDC-101 DPP4 FA-H GDC-0068 GSK1120212 IFNW1 Igfbp1 ITF2357 Ki 20227 Laquinimod LRRFIP1 antibody Met MLN4924 Nr4a1 PD153035 PDPN Ptprc Quizartinib Rabbit Polyclonal to AARSD1. Rabbit polyclonal to ANKRD33. Rabbit polyclonal to EIF1AD. Rabbit Polyclonal to Histone H2A phospho-Thr121). Rabbit polyclonal to Smac Rabbit polyclonal to ZNF200 RL SB-262470 SB-408124 SH3RF1 Sirt6 SQLE Tedizolid VEGFA Veliparib Wisp1 Zanosar
©2021 AK and SYK kinases ameliorates chronic and destructive arthritis Entries (RSS) and Comments (RSS) Child theme Enough Child of enough Theme


Nemesida WAF includes the Nemesida Scanner module, which is designed to detect vulnerabilities and access critical data of a protected web-application.
Using the security scanner allows you to identify the vulnerabilities of the web-application and notify the owner of the resource. In the context of protecting a web-application, the identified vulnerabilities will be additionally protected by virtual patching rules.
Critical data in the public domain.
The scan results are available in the Nemesida WAF personal account.


text:
David Cadman QC
1996 - Silk 2021
1992 - Durham University - B. A. (Hons) (Dunelm)
1996 - Inns of Court School of Law, Bar Vocational Course - Very Competent
1996 - 1997 - Pupillage (1st Six and 3rd Six) at Goldsmith Chambers. Pupillage (2nd Six) at Bridewell Chambers
1997 - 2003 - (and 2007 to 2011 jointly also as a member of Sovereign Chambers) Tenant at Goldsmith Chambers
2003 - 2011 - Tenant at 30 Park Square Leeds
2005-2006 and 2011 - Misick & Stanbrook, Turks and Caicos Islands. I did two short stints with Misick & Stanbrook as a Senior Litigation Attorney in 2005/6 and 2011.
2012 - present - Founding partner and senior litigation attorney with Griffiths & Partners, Turks and Caicos Islands
2021 - Appointed Queens Counsel
1996 - Called to the Bar of England & Wales
1996 - Lincoln's Inn
2005 - Called to the Bar of the Turks and Caicos Islands
2005 - Member of the Bar Association of the Turks and Caicos Islands
2018 - Member of the Bar Council of the Turks and Caicos Islands
1993 - Lincoln's Inn Scholarship
2018 - Chambers Global Ranked Individual
David is unavailable to accept instructions at the moment.
David has broad litigation experience covering a wide range of commercial, contractual, property and regulatory disputes.
His work includes an emphasis on complex disputes generally. David regularly advises and acts in document-heavy contentious matters. Having spent a decade engaged in criminal cases at the Bar in England, both prosecuting and as defence counsel, in recent years David has been involved in many complex contested trials working with international legal teams in multi-jurisdiction litigation, including Norwich Pharmacal applications, interlocutory freezing orders and other injunctive relief.
David has considerable experience working with legal teams in the USA in particular.
Latest from David Cadman QC
David Cadman sworn in as QC in the Turks & Caicos Islands
David Cadman appointed QC by the Governor of the Turks and Caicos Islands


text:
Bucs to Leave from Raymond James Stadium
The Tampa Bay Buccaneers will depart for St. Louis, site of the NFC Championship Game, on Friday, January 21, at 2:00 p.m. Fans who wish to send the team off personally can do so at Raymond James Stadium, the Bucs' departure point.
Fans who come to Raymond James Stadium for the sendoff may park in Lot 6D, just to the south of the stadium on the corner of Himes Avenue and Tom McEwen Boulevard. Lot 6D will open at 10:00 a.m. on Friday morning. Fans will then be directed to waiting areas at Entrance B of the stadium.
"Fan support is always great," said LB Hardy Nickerson. "Hopefully, we can go out there and make our fans proud. They were great when we won the division; hopefully, we can come back with an NFC championship this time."


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South African Railways; Riding the Shosholoza Meyl
The Shosholoza Meyl train is a gentle introduction to private trains!
Private Railways
The Dining Car – dimly lit for atmosphere
Shosholoza Meyl, Life on Board
Private railway travel evokes some rather splendid images; The Orient Express and The Golden Eagle are but two of the companies offering the most luxurious of travel on board their private railway carriages. And wonderful they are too, to which I can attest.
However, the Premier Classe product, on their Shosholoza Meyl train, offered by South African Railways is in a different league altogether, and it is welcome and a most interesting experience.
Shosholoza Meyl, South African Railways
The bar car – sadly closed when needed after dinner
The operator is Shosholoza Meyl, a division of the Passenger Rail Agency of South Africa. The product is straightforward; passage between Johannesburg and Cape Town or Durban, with each route operating once or twice per week.
The train is elderly; built about eighty years ago and the carriages have been refurbished many, many times. With a little imagination, I think, it is possible to catch a hint of the scent of steam trains, unforgettable for those of us who were around in the Days Of Steam. Today they are comfortable, in the way of an older seaside boarding house, and more than serviceable.
The dining car was dimply lit for "atmosphere"; but the effect was really pretty dreary
The train is long; seven sleeping carriages each offering accommodation in eight two or four-berth cabins, two dining cars, one bar car and a smoking wagon (at the very back). This seemed a touch over the top for the twenty-one of us that boarded in Johannesburg, but there you are. The train is a set, and all eleven carriages travel together, plus a required and variable number of car-carriers, for a number of passengers use this service instead of driving to the coast.
This operation should not be compared to the Blue Train.
Firstly, the price; passage in/on Premier Classe costs R3,150 (US$250). In comparison, passage on the Blue Train starts at R15,000 ($1,250) in the low season, and R19,000 ($1,500) in the peak. Mind you, the Blue Train starts in Pretoria, thus avoiding the rather dystopian centre of Johannesburg where the Premier Classe originates, and they stop for a glass of sherry at Matjiesfontein on the northbound journey and a quick whizz around the diamond centre at Kimberley on the southbound leg.
The Premier Classe lumbers along.
The Groovy Bar Stools
I rather liked it. My cabin was small but perfectly proportioned, the bed comfortable and the linen fresh. The housecoat, which we were admonished to leave behind, let the side down a bit, but was functional. The room was warm, the lighting good and the electrical supply sufficient to keep my phone in action.
The lounge car was pleasant in a dated way. It felt comfortable and familiar, the familiarity that comes with venues of decades of ribaldry and boozing; slightly awkwardly furnished, and too small if the train were full, it would have been a fine place to while away the evening had it been open.
Curiously, it was open as we boarded and were led into the bar car to be offered champagne and a briefing about the trip. It remained open until just prior to dinner, which was served early for some reason, but when we emerged, sated but in need of a night-cap or two at eight o' clock, it was oddly shuttered.
The food was plentiful, and again, most certainly not The Blue Train, but more than adequate. Three courses at lunch and five in the evening were generous and ample given the lack of recreational space available. The service, it must be said, was generally cheery, although sometimes slightly off key. The wine list was good, with bottles ranging from R80 ($6), but oddly, non served by the glass. Mind you, at those process one could simply order another bottle.
The journey was lovely. Once past the endless, dreary and emphatically-littered suburbs of Johannesburg, and before the same grim outskirts that heralded our approach to Cape Town, thee scenery was lovely, and the light delightful.
The evening rolled along as we passed through endless Savannah, with wispy bushes, the dry ochres of winter and a clear blue sky that gradually melted into sunset. By the next morning we were in hillier country that rose to become snow covered mountains on each flank of the valley through which we rattled along.
Sunset and dawn over the South African veldt
When we woke, vineyards were everywhere; the wealth of this precious commodity there for all to see. Village life, the unfolding countryside and the evidence of the fierce storm that had hit two days previously punctuated the landscapes, and pretty soon we were running late. It mattered little, as for most travellers who choose the train, we are there for the sense of timelessness that rail travel can still offer in this hectic age.
Paradise, our main man on board, kept things going pretty well inside the train, but alas had no control over signals and the speed of other locomotives. Thus, our affection for timelessness was well placed, for we had three bonus hours and an unexpected lunch, and finally rolled into the Cape Town station at about 3.30pm.
It was a lovely trip. It is a perfect way to travel between the great South African cities; not quite a simple overnight train, and yet not quite the ambiance of a private-train. It was a fine hybrid, and all the more enjoyable for the foibles that can only come with eighty-year-old rolling stock, many times refurbished, a multinational passenger group and the warmth that comes from being in the company of staff who are happy to be there, and more importantly, happy that you are there too.
It is most certainly a trip to be recommended and repeated.
Vineyards of the Western Cape
when is the train coming back, please let me know we want to book for 2022
MaxGlobetrotter
March 18, 2022 @ 7:49 am
I don't know about its revival; I would keep in touch with AndyB Travels, a first rate railway agent.


Red, white and blue honor cords are available to graduating veteran and military students attending a CCC graduation ceremony. These cords signify CCC's appreciation for their service and dedication.
The honor cords are purchased by the Veterans and Military Resource Center and are yours to keep. There will be a group photo taken before the graduation ceremony and you must register to receive the honor cord and additional information.
All SALUTE/Phi Theta Kappa graduating students who plan to walk at commencement will be eligible to receive the SALUTE graduation stole honoring their military service if they earned an honorable discharge or they are on active duty or in active drilling status and have completed all requirements eligible of PTK regalia, including a minimum 3.5 GPA.
If yes, where are you transferring to?


to provide additional data, or to correct any errors.
103. George "Dode" Nesbitt. Son of Thomas Nesbitt (link to Nesbitt family pages)& Janet Little. Born 29 Nov 1874 in Harvey. Died 1929 in Harvey. Occupation Farmer.
Unmarried. Farmer, lived on farm where Alvin Moffitt presently lives.


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Żarnowiec è un comune rurale polacco del distretto di Zawiercie, nel voivodato della Slesia.Ricopre una superficie di 124,77 km² e nel 2004 contava 5.011 abitanti.

Altri progetti

Collegamenti esterni

Żarnowiec

redpajama_set_name: RedPajamaWikipedia


ARPP-16, ARPP-19, and ENSA are inhibitors of protein phosphatase PP2A. ARPP-19 and ENSA phosphorylated by Greatwall kinase inhibit PP2A during mitosis. ARPP-16 is expressed in striatal neurons where basal phosphorylation by MAST3 kinase inhibits PP2A and regulates key components of striatal signaling. The ARPP-16/19 proteins were discovered as substrates for PKA, but the function of PKA phosphorylation is unknown. We find that phosphorylation by PKA or MAST3 mutually suppresses the ability of the other kinase to act on ARPP-16. Phosphorylation by PKA also acts to prevent inhibition of PP2A by ARPP-16 phosphorylated by MAST3. Moreover, PKA phosphorylates MAST3 at multiple sites resulting in its inhibition. Mathematical modeling highlights the role of these three regulatory interactions to create a switch-like response to cAMP. Together the results suggest a complex antagonistic interplay between the control of ARPP-16 by MAST3 and PKA that creates a mechanism whereby cAMP mediates PP2A disinhibition.
This model is hosted on BioModels Database and identified by: MODEL1707020000.
Abstract: ARPP-16, ARPP-19, and ENSA are inhibitors of protein phosphatase PP2A. ARPP-19 and ENSA phosphorylated by Greatwall kinase inhibit PP2A during mitosis. ARPP-16 is expressed in striatal neurons where basal phosphorylation by MAST3 kinase inhibits PP2A and regulates key components of striatal signaling. The ARPP-16/19 proteins were discovered as substrates for PKA, but the function of PKA phosphorylation is unknown. We find that phosphorylation by PKA or MAST3 mutually suppresses the ability of the other kinase to act on ARPP-16. Phosphorylation by PKA also acts to prevent inhibition of PP2A by ARPP-16 phosphorylated by MAST3. Moreover, PKA phosphorylates MAST3 at multiple sites resulting in its inhibition. Mathematical modeling highlights the role of these three regulatory interactions to create a switch-like response to cAMP. Together the results suggest a complex antagonistic interplay between the control of ARPP-16 by MAST3 and PKA that creates a mechanism whereby cAMP mediates PP2A disinhibition.
We use COPASI 4.19 (Build 140) to reproduce Figure3b (the blue line) from the paper.


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HC quashes case against CPI (M) leader Vasuki
The Madurai Bench of the Madras High Court on Monday quashed the trial court proceedings pending against CPI (M) Central Committee Member U. Vasuki and 25 other party members. In 2016, during the campaign for the State legislative Assembly elections they had staged a road blockade in Jaihindpuram in Madurai alleging police inaction over distribution of cash for votes.
The case of the prosecution was that on May 13, 2016, around 250 CPI (M) party members had staged a protest in Jaihindpuram in Madurai. They had raised slogans against the police at around 8 p.m. in violation of election code and prohibitory order. The petitioners said that they had only raised the slogans and there was no violence. They said that the continuance of the case against them was harassment and sought the quash of the proceedings.
Justice G. R. Swaminathan took note of the fact that the petitioners had blocked the Jaihindpuram road, they raised slogans against the police during the 2016 election campaign and there was no damage to property. The court said that the assembly of the petitioners was a legitimate exercise of their democratic right and it cannot be said to be an unlawful assembly.
They had staged a protest against the distribution of cash by the political rivals. Rampant use of cash for votes was an electoral reality, the court said. The court observed that the life of the 2016 election itself was over and the 2021 election was also held. The court held that the continuance of the proceedings against the petitioners was not warranted and quashed the trial court proceedings pending against them before the Judicial Magistrate IV, Madurai.
In 2016, CPI (M) Senior leader Vasuki who was contesting from the Madurai West constituency staged a protest along with 250 party members. The party members said that they had caught a few people of the AIADMK party who had indulged in distribution of cash for votes. The police had arrived at the spot. But, later the police let off the people who had indulged in the distribution of cash for votes, the petitioners said.
Coach Nambiar brought home the difference a coach could make to an athlete's career
The tale behind a Tagore bust
Boy influenced by man to remain in Saranalayam
Centre urges speedy hearing of income cut-off for EWS quota
EdTech regulation policy on the anvil: Education Minister Dharmendra Pradhan
Fans Are Throwing All the Fire Emojis at LeAnn Rimes's Incredible Cut-Out Dress
Don't be complacent with pandemic, Kumaraswamy tells Govt.


Making New Year's Resolutions? Consider the Environment!
Small steps can lead to big change. So while inspiring others to increase their environmental engagement, NEEF's staff is renewing their own commitment to positive environmental actions. Read below for NEEF staff's environmental pledges for 2018 and remember to include the environment when making your own goals for the New Year.
"In 2018, I resolve to skip a bag when I forget to bring along reusable shopping bags on grocery runs."


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First Flight of Third 767 AWACS
The third Boeing 767 AWACS takes off from Boeing Field in Seattle during its successful first flight on Aug. 31. The flight marks the beginning of a test program to evaluate whether the aircraft's radar, navigation, computers/displays, mission systems and communication systems perform as designed. Aircraft number three is one of four 767 AWACS sold to the government of Japan. Two have been already delivered. The other two will be delivered early next year.


The privacy of the patients and families at Emory Decatur Hospital, Emory Hillandale Hospital and Emory Long-Term Acute Care is of the utmost importance. To get information about a patient, you must contact a Media Relations representative. Requests for all staff and patient interviews must also be coordinated through our Media Relations department. In addition, when visiting any of our campuses members of the media are required to be escorted by a member of Media Relations department at all times.


The most common illegal ground for terminating a New Mexico employee is discrimination. An employer cannot terminate an employee simply for being of a specific race, nationality, religion or gender. Employers in Hobbs may also not terminate at-will employees as an act of retaliation if they have filed a legal discrimination claim or initiated an investigation into discrimination.
Attorneys in Hobbs, New Mexico may be able to inform you as to whether a wrongful termination has occurred, and can assist you in collecting the required documents for your case. There may also be unique or unfamiliar procedures, and an attorney can guide you through these as well.


Our hospitality page will show virtually all Public Houses in the Aldergrove area. Choose either the best reviewed pubs or the ones nearest to you. Enjoy!
I am a great believer in "food doth not a restaurant make." Alas, customer service plays a very vital role. Chan is fantastic for this. I could ring looking something off menu and he will create without any hassle. Would recommend to all. Brilliant customer service and a friendly face.
Good, standard Indian food. They made a couple of errors with the orders initially but I have had many repeat orders with no issue. It's good to have an Indian takeaway near.
Excellent value for money and consistently good food, friendly staff and fast efficient service... and it's on our doorstep! A local gem. This is my Saturday night staple (and some weeknights too!). Farouk and his family are the salt of the Earth.


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Medovate
Ground-breaking regional anesthesia system to become available in Saudi Arabia, the UAE and Bahrain
UK-based Medovate – a dynamic medical device development company – has today announced an agreement with AKSIA...
Medovate announces first distribution agreement for SAFIRA™ in Asia
Medovate – a dynamic medical device development company specialising in anesthesia, airway management, critical care, and surgery...
Queen Elizabeth Hospital King's Lynn invented device awarded HSJ Patient Safety Innovation of the Year
A ground-breaking regional anaesthesia device, invented by clinicians at The Queen Elizabeth Hospital King's Lynn NHS Foundation...
Jim Beyer joins Medovate as US Commercial Executive Consultant
Medovate – a dynamic medical device manufacturing company based in Cambridge, UK – have announced that Jim...
Medovate expands SAFIRA® product range with further CE Mark Regulatory Approvals
Medovate – a pioneering medical device development company – has today announced it has successfully secured additional...
Medovate unites with Konica Minolta Healthcare Americas Inc. to promote best practice in regional anaesthesia
Medovate has announced a newly formed partnership with Konica Minolta Healthcare Americas, Inc. to promote best practice...


Sungtae Kim gained experiences in auditing and HR before completing Masters in Strategy, consulting & digital transformation at EDHEC Business school in France.
He then joined Amadeus IT in Nice as a business analyst. He initiated a project for strategic partnership with a leading IT company and engaged in multiple internal consulting projects for data analytics.
He later joined PTOLEMUS in Brussels office and has taken part in various projects for go-to-market strategy and market research. Throughout multiple interviews with industry experts and market analysis, he has gained expertise on the UBI market and fleet management.
He is in charge of PTOLEMUS UBI dashboard and business intelligence report. He follows the global UBI market trends and updates the market overview.
Sungtae is fluent in English and Korean.


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Abram-Tyube () is a rural locality (an aul) in Tukuy-Mektebsky Selsoviet of Neftekumsky District, Stavropol Krai, Russia. The population was 1,059 as of 2010. There are 7 streets, a kindergarten and a secondary school.

Etymology
The village's Nogai name, "Abram-Tobe avyl" (Abram-Tobe aul), refers to a large mound located west of the village that was named after a shop owned by an Armenian named Abram. The name translates to "Abrama Kurgan" and means "Aul (mound) Abram-Tobe." The village has also been known as "Abramo-Tyube" and "Abramtyube."

History
According to the 1926 census, the village of Abram-Tyube had 150 households with a population of 598 people, including 328 men and 270 women. The majority of the population, 567 individuals, were Nogais, while the rest were of other ethnicities. In 1929, the village had a school and served as the administrative center of the Abram-Tyube village council, which was part of the Achikulak district of the Dagestan ASSR.

Before May 1, 2017, Abram-Tyube was part of the Rural Settlement Tukuy-Mektebsky village council in the Neftekumsk municipal district of the Stavropol Territory.

Geography
Abram-Tyube is located 87 km south of Neftekumsk (the district's administrative centre) by road. Tukuy-Mekteb is the nearest rural locality.

Demography

According to the 2002 census, the national structure of the population in the village showed that Nogais accounted for 52% of the population, while Dargins accounted for 38%.

References

Rural localities in Stavropol Krai


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Q: Creating a new column and pasting data into that new column with VBA I am attempting to create a new column on a different sheet and then copy data into that column.
Below is the code I have written. The first sub is a new column to the left and the second sub is the column to the right.
The insert column part is working. I hid a column and have a cell in there as a named range which I used to select in my macro. The data I want to copy is on the Input sheet and is named InputData.
Dim sourceSheet As Worksheet
Set sourceSheet = ActiveSheet
Sheets("Data").Activate
Sheets("Data").Range("DividerColumn").Select
Selection.EntireColumn.Offset(0, 0).Insert Shift:=xlToLeft
'Sheets("Input").Activate
'Range("InputData").Copy
'Sheets("Data").Activate
'ActiveCell offset maybe?
'Range().PasteSpecial xlPasteValues
Call sourceSheet.Activate

End Sub

Dim sourceSheet As Worksheet

Set sourceSheet = ActiveSheet

Sheets("Data").Activate

Sheets("Data").Range("DividerColumn").Select

Selection.EntireColumn.Offset(0, 1).Insert Shift:=xlToRight

Call sourceSheet.Activate

End Sub

A: Oh I didn't see your copy range. In that case this could probably work. I see you just got the answer, but this would be a good way to avoid select.
Sub copyToLeft()
   Call doTheCopy(False)
End Sub
Sub CopyToRight()
   Call doTheCopy(True)
End Sub

Private Sub doTheCopy(goRightIsTrue As Boolean)
   With Sheets("Data").Range("DividerColumn").EntireColumn.Offset(0, IIf(goRightIsTrue, 1, 0))
      .Insert Shift:=xlToRight, CopyOrigin:=xlFormatFromLeftOrAbove
      .Offset(0, -1).Value = Sheets("Input").Range("InputData").EntireColumn.Value
   End With
End Sub

A: I found the solution by using an offset function. Below is my code. Hope this helps someone with a similar situation.
   Dim sourceSheet As Worksheet
   Set sourceSheet = ActiveSheet
   Sheets("Data").Activate
   Sheets("Data").Range("DividerColumn").Select
   Selection.EntireColumn.Offset(0, 0).Insert
   Shift:=xlToLeft
   Sheets("Input").Activate
   Range("InputData").Copy
   Sheets("Data").Activate
   Range("DividerColumn").Select
   ActiveCell.Offset(0, -1).PasteSpecial
   xlPasteValues
   Call sourceSheet.Activate

   End Sub

-1 in the offset function moves your active cell to the left one cell and then 1 moves it to the right. So once the column is created, either right or left, my macro goes and copies the information and then goes back to the sheet I want it to and selects my named range again and then it gets moved to the left and pastes my data.


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Feeling like a million miles away from home? Well-being at work of expatriates in the resources sector in Indonesia
Apriyanti526603-Accepted.pdf (798.6Kb)
File version
Accepted Manuscript (AM)
Apriyanti, H
Hutchings, K
McPhail, R
Hutchings, Kate
McPhail, Ruth E.
As the world of business becomes increasingly globalised, there is greater mobility of workers internationally. Prior research has found expatriates (and their families) experience work and cultural stressors when living and working in host countries, and the stressors may be greater when working in remote locations. This research explores perceptions of well-being a of expatriates at work in the resources sector, including how social capital impacts on the well-being of expatriates. The research was undertaken in Indonesia and involved semi-structured in-depth interviews with 43 resources sector expatriates, 8 spouses and ...
View more >As the world of business becomes increasingly globalised, there is greater mobility of workers internationally. Prior research has found expatriates (and their families) experience work and cultural stressors when living and working in host countries, and the stressors may be greater when working in remote locations. This research explores perceptions of well-being a of expatriates at work in the resources sector, including how social capital impacts on the well-being of expatriates. The research was undertaken in Indonesia and involved semi-structured in-depth interviews with 43 resources sector expatriates, 8 spouses and 7 human resource managers who provided their perceptions of the well-being of expatriates at work. The findings highlight nine aspects of well-being at work for expatriates in the resources sector in Indonesia, including: social aspect, safety/security, benefits and disadvantages, work aspects, job and other attitudes, eudaimonic aspect, work-life balance, affect and external influences. The findings particularly emphasise the importance of safety, work life balances and external (organisational) influences. The research contributes to expatriate, well-being and social capital literature by providing an understanding of well-being at work for expatriates working in non-standard (often remote) workplaces in the resources sector. While the research was undertaken in Indonesia and includes context-specific examples from this developing country, the conceptualisation of well-being at work has broader application for employees working in non-standard workplaces across many sectors and contexts.
German Journal of Human Resource Management
Apriyanti, H; Hutchings, K; McPhail, R, Feeling like a million miles away from home? Well-being at work of expatriates in the resources sector in Indonesia, German Journal of Human Resource Management, 2021. Copyright 2021 The Authors. Reprinted by permission of SAGE Publications.
This publication has been entered as an advanced online version in Griffith Research Online.
Political economy and social change


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Keurig Is Now Selling a Pod Machine That Makes Cocktails
The Drinkworks Home Bar can make 15 different cocktails, plus beer and hard cider.
By Minda Zetlin, Co-author, The Geek Gap@MindaZetlin
Drinkworks
You may soon be able to serve cocktails to yourself and your friends by putting a pod into a Keurig-style machine and pushing a button. Drinkworks, a joint venture of Keurig and Anheuser-Busch, is selling its first product, the Drinkworks Home Bar, by mail order and at a few select retailers, exclusively in St. Louis. Expansion to other markets is planned for 2019. (The daunting legalities of shipping alcohol between or even within states means they can't just sell the pods on Amazon, for example.)
For those who can get them, the machines cost $299, and the pods cost $3.99 each, or $15.99 for four. Users put in water, and also have to install a CO² cartridge (the machine comes with the first two) that can make an average of 12 drinks. At launch, the Drinkworks Home Bar can make 15 different cocktails, ranging from a G&T to a Long Island Iced Tea to Sangria to a White Russian or Mai Tai, or three different kinds of Margarita. It can also produce a couple of brands of beer and even a hard cider.
A lot of the technology inside the Drinkworks machine likely descended from Keurig Kold, Keurig and Coca-Cola's attempt to challenge Pepsi-backed SodaStream's dominance of the at-home soda market. The Keurig Kold had the advantage of making drinks one at a time, and of offering Coca-Cola as well as other Coca-Cola-owned beverages, such as Sprite. But those upsides couldn't overcome the Kold's significant price disadvantages. The machine cost $299 and up, and the pods started at $3.99 for a pack of four, with each pod producing an 8-ounce beverage, smaller than a standard can, at least in the U.S. Keurig had to give up on the Kold after less than a year.
Keurig and its beer-behemoth partner are betting that the calculus will be different for alcoholic beverages. The product has met with skepticism in the press so far, but I think they might be on to something. Coffee and soda, and for that matter beer, are beverages people often drink at home, and they usually only want one or two kinds. But the Keurig and its pods really come into their own in places like waiting rooms and lobbies, where many different people can each have the hot beverage they like most.
Likewise, I don't see much reason for the Home Bar for just me if I always drink the same cocktail every evening--it would be cheaper and simpler to go out and buy the appropriate ingredients (or, even easier, a mix) and make it myself. But if I'm having a party with 30 or 40 people who each want a different drink, then the Home Bar has a lot of appeal. Plus, it's fun. It even has its own iPhone app, so you can monitor its progress while it makes your drink. (The process is different for different beverages--the machine reads a bar code on the pod to figure out what to do--and most or all drinks can be made in a minute or less.)
I've never wanted a Keurig machine, but if the Home Bar goes on sale in my area, I might be seriously tempted to get one before my next big party. Or even my next book group gathering. Will other consumers feel the same way? We'll have to wait and see.


This class A military tunic was worn by Gary Cooper as Jonathan L. "Scotty" Scott in the war time epic Task Force. The garment was custom made specifically for Mr. Cooper by Macintosh, and has their label sewn into the right breast pocket. Gary Cooper Feb 4th, 1943 is hand written in black ink. The insignia which dresses the uniform coat is for display purposes only, the original insignia was removed for use in a subsequent production.
Mr. Cooper can be seen wearing the jacket when he visits his love interest Mary, a nurse at a medical ward. The garment is viewed in closer detail at the Senate Hearing Committee, where he argues that the US needs more naval aircraft carriers in order to win the war. This garment is in excellent vintage screen worn condition and is accompanied by a letter of authenticity.


text:
'The Contra-Connoisseur's Guide to Wine, Beer, Spirits And Other Stuff The World Got Right'.
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'Zin Zone', Zabaco And Zsa Zsa Gabor →
Eenie, Meenie, Santorini: Wines To Serve With Prawn Linguini
Posted on March 4, 2013	by intoxreport
L.: Olympians. R.: Zombies
120 miles southwest of mainland Greece there is a wisp of an island upon which mighty things have happened, are happening, and—the Twelve Olympians willing—will continue to happen long after you and I are riding point during the zombie apocalypse.
Although its official name is Thira, most of the world has referred to it as 'Santorini' since the third century AD when Fourth Crusade snatched it the Byzantine Empire and re-named it in honor of St. Irene—a non-Olympian for sure.
Stem to stern, Santorini is all of 35 square miles in size—roughly the same as Manhattan. But unlike the Big Apple, whose population density is around 70,000 per square mile the Big Assyrtiko Grape spreads them a bit thinner at 400/ sq. mi., and the fifteen thousand people who call the Cycladean archipelago home boast a heritage that has survived earthquakes, volcanoes, droughts, pissed-off Christians and collapsing Minoan ruins, and are riding out the current Greek economic implosion with steeze and swagger. Among the most popular tourist destinations on the planet (voted the world's 'best' island by Travel + Leisure magazine in 2011) Santorini continues to float upon a cash-flow bubble while the rest of the country watches salaries and pensions fade into an Ionian sunset.
And one of the reason is Santorini's unique, volcanic wine.
Greco-Roman Style
Marco Sanudo
Wine has been a cultural backbone in Santorini for as long as history has been recorded, but it wasn't until the Italians stuck their boot into the barrel that things began to heat up. One of the Fourth Crusade's leaders was a wealthy Venetian called Marco Sanudo, and he wound up in control of the Cyclades following the decision of the Holy Warriors to forego Jerusalem and sack Constantinople instead. They did; they won; they took over the territorial portfolio.
Nephew of Venetian doge Enrico Dandolo, Sanudo was named first Duke of the Duchy of the Archipelago, and under his influence, the wines of Santorini began to be exported throughout the ancient world.
Like most of the world's great wines, Santorini's are the product of poor soil and a Mediterranean climate characterized by warm temperatures, low rainfall but high humidity during the growing season. During the Duke's era, they proved to be unusually high in sugar and alcohol and as such were particularly suited for long sea voyages. So valued were they that, as Mick Jagger's Start-Up girl could make a grown man cry and a dead man (intransitive verb meaning 'to splooge'), Santorini's wine could make a Muslim man millions—despite the Koran's edict forbidding trading in alcohol.
Jagger and Jihad
Blaming the island's lousy geography, which made other cash crops impractical, the Ottoman Turks—who captured the region in 1579—encouraged the wine industry, and in fact, when the Russian Orthodox Church made Santorini the official producer of Eucharistic wine, the Turks kept the pipeline flowing freely even though they were at war with Russia more years than not.
AAA: Indigenous Insurance, Baby…
Euphemus
Three ancient varietals are Santorini's workhorse grapes: The triple 'A' gang of assyrtiko, athiri and aidani has been producing quality white wine essentially since Santorini was created by Poseidon's son Euphemus as a place to hide his pregnant girlfriend. Although they can now be found planted throughout Greece, nowhere does the trio produce wines of such depth and complexity—due mainly to the unique Cycladean terroir. *
* French etymology notwithstanding, the Greeks invented 'terroir' as a selling point by stamping amphorae with the seal of their region of origin; different regions soon established individual reputations based on quality.
Assyrtiko is the premiere white grape of Santorini, prized for its productivity and versatility. Not only did it first find life in Santorini, it has reached heights in this barren, river-free, shield-volcano complex that far outstrip the quality of assyrtiko grown on the mainland. This the result of the easy-draining ash that makes of up the island's soil; it's called 'aspa' and not only is it rich in trace minerals, but its porosity seems to make Santorini vineyards impervious to the old enological enemy phylloxera. As a result, you'll find no grafted rootstock on Santorini, and some of the assyrtiko vines have been producing wine for three centuries. Over the course of time, assyrtiko has developed certain unique characteristics found only here; most notably, when grown amid the black pumice and clay-free sand, the grape displays an extraordinary ability to maintain a natural equilibrium between acid and sugar, even when fully ripe. Equally, the fog that envelops the island during the night—a consequence of the active volcano and sea water—is absorbed by the soil and transferred to the vine roots, giving these wines an intriguing note of brine, making it a sublime match for local seafood dishes.
Especially prawn linguini.
Athiri
The lineage of athiri on Santorini may date back even further than assyrtiko; in fact, it is named for the island's classical cognomen Thēra. Vinified alone, athiri does not reach assyrtiko's Olympian heights; it tends to work best as a blending grapes to temper the high acidity and alcohol of assyrtiko, especially in the production of vinsanto (about which more will be said directly). It is in nearby Rhodes that the grape has found an ideal host habitat, and there it is used to produce not only a delicate, lemon-scented, highly-regarded single varietal wine, but Greece's only Méthode Champenoise.
Snorting jasmine, faerie-style
The last member of the Thira Three, aidani sports a profile somewhere between assyrtiko and athiri with moderate acidity and middling alcohol; it is also, often a component of vinsanto. In blends, it lends aromatics to wines that might be otherwise light on the nose, especially the kind of floral scents associated with muscat (jasmine and honeysuckle) and the tropical fruit tones often seen in California chardonnay.
Vinsanto, on the other hand, has been the most widely celebrated and distributed of Santorini's wines for thousands of years. Don't be guiled by the guidos—the Italians talk a good game when it comes to vinsanto, but any claim to them having invented it can be dispelled soon enough: Vinsanto is a contraction of 'Vino di Santorini'. Beside, in production methods, style and substance, both the Venetian version and the Tuscan translation are different beasts entirely.
Italian grapes drying
For starters, Italians dry their chosen varietals—trebbiano and malvasia—on mats; indoors, in attics or under staircases, generally in darkness, while the Greeks spread their late-harvested assyrtiko (et al.) on hillsides outdoors and rely upon the benevolence of Apollo Helios to turn them into raisins—a much quicker process that gives vinsanto (as opposed to the two-word 'vin santo') its characteristic volatility.
Assyrtiko drying and St. Apollo, who dries them.
The Italian incarnation is dubbed 'Holy Wine' because it is produced exclusively in the week preceding Easter, and it may be as dry and oxidized as oloroso sherry. Greek vinsanto is naturally sweet, although it is a bit disingenuous to label it 'dessert wine' since the pronounced acidity makes it suitable for most courses.
In 2002, EU legislation found that there was sufficient evidence to prove vinsanto's Santorini provenance and ruled that this Greek island was the only appellation in Europe able to label its sweet, sun-dried wines as such.
The Italians would have to settle for 'vin santo' or 'vino santo' or pound sand down a bingo-bongo bung-hole.
A couple other concepts round out Santorini's remarkable and venerable wine traditions:
Making brousko on Santorini
Mezzo, a less cloying version of vinsanto, is made from partially raisined assyrtiko grapes—and obviously, without the sugar stasis, the wine tends to be overtly acidic and not really a Western palate-pleaser.
Brousko may date from the island's Venetian occupation, but it is suitably up-to-date with its color-blind view of the world—it can be red, white or pink. The word 'brousko' refers to a method more than a specific wine: To produce it, local grapes are held in bins for several days, then crushed by hand, which means foot and fermented with skins, stems and seeds included. Brousko has mostly fallen from grace on Santorini, where free-run juice is now nearly de rigueur, and although it can still be found in isolated pockets around the island, it is not exported.
Cáilín álainn
(The following wines were sampled through the courtesy of a distinctly non-Hellenic cailín beag I met when I ran the 'Guess Your Name' booth at the State Fair. I will say that she is so overwhelmingly Irish-looking that I instantly guessed 'Jen O'Flanagan' and, you know what?
She didn't win the six-foot stuffed Scooby Doo. I did.)
Hatzidakis Dry White, Santorini, 2010, about $20: Surprisingly full-bodied, this blend of the tried 'n' true triumvirate (assyrtiko, athiri and aidani for those who have been nodding out) offers a full range of lemon and lime flavors rounded out with some chalky brine, unripe peach, honeysuckle and a vibrant, bracing bite of acidity.
Domaine Sigalas Assyrtiko, Santorini, 2011, around $20: Sharp and shivery, the wine exhibits a nose that is predominately citrus—lemon peel in particular with whiffs of peach and pomelo. Dryza-bone but with contrasting notes of honey and saltiness; a sensational mealtime bevvie (see recipe) with high-toned minerality and a bit of oak on the finish.
San Torini Vinsanto, Santorini, 2005, about $35 (500ml.): Textbook vinsanto, only with so many footnotes and citations that you'll spend a lot of wonderful time working out the coppery-red complexities. There's fig, espresso, kirsch and hazelnut in the nose, coffee and toffee mid-palate, everything drizzled with honey and lemon. It would sit well with a caramel-based dessert, but I tried it with pumpkin soup and it proved to be a perfect pairing.
Garlic Prawn Linguini
1 lb. linguine
3 tbsp Santorini Assyrtiko
1 tbsp. Parmesan cheese
small handful chopped fresh parsley
1 ¼ lbs. fresh prawns, peeled and deveined
1. Bring a large pot of lightly salted water to a boil. Add pasta and cook for 8 to 10 minutes or until al dente; drain.
2. In a frying pan, melt butter over medium low heat; add wine, cheese, garlic, parsley and salt and pepper to taste. Simmer over low heat for 3 to 5 minutes, stirring frequently.
3. Increase heat to medium high and add prawns to pan; cook for 3 to 4 minutes or until prawns begins to turn pink. Do not overcook.
4. Divide pasta into portions and spoon sauce and prawns on top; garnish with Parmesan cheese and fresh parsley.
This entry was posted in GREECE and tagged aidani, assyrtiko, athiri, Jen O'Flanagan, Santorini wine, Vinsanto. Bookmark the permalink.
2 Responses to Eenie, Meenie, Santorini: Wines To Serve With Prawn Linguini
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text:
class Sparky
  # Shortcut for Lorem.create
  #
  # Example:
  #   Lorem(:words, 10)
  def self.lorem (type = :sentences, count = 1)
    Lorem.create(type, count)
  end

  def self.name
    Name.create
  end
end

redpajama_set_name: RedPajamaGithub


Two broken souls find each other at a desolate East Texas motel. They find revenge and redemption. But what neither of them expected was a tough little girl would link their fates and shape the rest of their short, tortured lives.
The Cutman release date is to be announced on Blu-ray, Cinema, DVD, VOD.
Notify me when Cutman is available.


text:
"use strict";

import url from 'url';
import path from 'path';
import gm from 'gm';
import Promise from 'promise';
import {log,error} from './utils';

function headers(contentType) {
  let extraHeaders = arguments.length > 1 ? arguments[1] : {};
  return Object.assign({
    'Date': dateHeaderValue(new Date()),
    'Content-Type': contentType
  }, extraHeaders);
}

function dateHeaderValue(dt) {
  return dt.toUTCString();
}

function handleFailedImageResponse(imageResponse, res) {
  let h = headers(imageResponse.headers['content-type'], {'Cache-Control': 'no-cache'});
  res.writeHead(imageResponse.statusCode, h);
  imageResponse.on('error', function(err) {
    error('handleFailedImageResponse imageResponse stream error: %o', err);
    try { imageResponse.close(); } catch(e) {}
    res.end();
  });
  imageResponse.pipe(res);
}

function failResponse(res, message) {
  res.writeHead(500, headers('text/plain', {'Cache-Control': 'no-cache'}));
  res.end(message);
}

class Processor {
  constructor(route, imageSource, imageQueue, options, processFunc) {
    this.route = route;
    this.imageSource = imageSource;
    this.imageQueue = imageQueue;
    this.processFunc = processFunc;

    if ('cacheExpiration' in options) {
      this.cacheExpiration = options.cacheExpiration;
    } else {
      this.cacheExpiration = null;
    }
    if ('socketTimeout' in options) {
      this.socketTimeout = options.socketTimeout;
    } else {
      this.socketTimeout = null;
    }
    if ('gifFirstFrame' in options) {
      this.gifFirstFrame = options.gifFirstFrame;
    } else {
      this.gifFirstFrame = false;
    }
  }

  process(context, res) {
    context.params = this.route.extractParameters(context.request);
    log('params: %o', context.params);
    return this._getImage(context, res).
      then( (image) => this._processImage(image, context, res) ).
      then( (image) => this._writeImage(image, context, res) ).
      then( () => this._cleanup(context) );
  }

  _processImage(image, context, res) {
    return this._executeProcessFunction(image, context).
      catch(function(err) {
        error("error in process function: %o", err);
        failResponse(res, err.message);
        return Promise.reject(err);
      });
  }

  _getImage(context, res) {
    let gifFirstFrame = this.gifFirstFrame;
    return this.imageQueue.push(this.imageSource, context, {socketTimeout: this.socketTimeout}).
      then(function(imageResponse) {
        if (imageResponse.statusCode != 200) {
          handleFailedImageResponse(imageResponse, res);
          return Promise.reject(new Error("Unexpected HTTP response code: " + imageResponse.statusCode));
        } else {
          context.imageContentType = imageResponse.headers['content-type'];
          context.imageLastModified = imageResponse.headers['last-modified'];
          log("received image: %s", context.imageContentType);
          let filename = path.basename(context.imageUrl);
          context.basename = filename;
          if (gifFirstFrame && filename.match(/\.gif$/)) {
            log('processing first frame of gif: %s', filename);
            filename = filename + '[0]';
          }
          return gm(imageResponse, filename);
        }
      }, function(err) {
        error("error fetching image: %o", err);
        failResponse(res, err.message);
        return Promise.reject(err);
      });
  }

  _executeProcessFunction(image, context) {
    let promise = null;
    try {
      log('executing process image function...');
      let result = this.processFunc(image, context);
      if (result == null || typeof result == 'undefined') {
        promise = Promise.reject(new Error('Expecting promise or image as result of process function'));
      } else if (('constructor' in result) && result.constructor == Promise) {
        promise = result;
      } else {
        promise = Promise.resolve(result);
      }
    } catch(err) {
      promise = Promise.reject(err);
    }
    return promise;
  }

  _bufferImage(image) {
    return new Promise(function(resolve, reject) {
      log("buffering final image...");
      image.toBuffer(function(err, buf) {
        if (err) {
          reject(err);
        } else {
          resolve(buf);
        }
      });
    });
  }

  _writeImage(image, context, res) {
    let proc = this;
    return this._bufferImage(image).
      then(function(buffer) {
        log("writing image...");
        context.imageFileSize = buffer.length;
        proc._writeResponseHead(context, res);
        res.write(buffer);
        res.end();
      }).
      catch(function(err) {
        error("error writing image: %o", err);
        failResponse(res, err.message);
        return Promise.reject(err);
      });
  }

  _streamImage(image, context, res) {
    log('streaming processed image...');
    let proc = this;
    return this._createImageStream(image, context).
      then(function(stream) {
        return proc._pipeStreamToResponse(stream, context, res);
      }, function(err) {
        error("error processing image: %o", err);
        failResponse(res, err.message);
        return Promise.reject(err);
      });
  }

  _createImageStream(image, context) {
    return new Promise(function(resolve, reject) {
      image.stream(function(err, stdout, stderr) {
        if (err) {
          reject(err);
        } else {
          resolve(stdout);
        }
      });
    });
  }

  _writeResponseHead(context, res) {
    let cacheExpiration = this.cacheExpiration;
    let h = headers(context.imageContentType, {'Last-Modified': context.imageLastModified});
    if (cacheExpiration) {
      h['Expires'] = dateHeaderValue(new Date(new Date().getTime() + (cacheExpiration*1000)));
      h['Cache-Control'] = "public, max-age=" + cacheExpiration;
    }
    if (context.imageFileSize) {
      h['Content-Length'] = context.imageFileSize;
    }
    res.writeHead(200, h);
  }

  _pipeStreamToResponse(stream, context, res) {
    log('sending transformed image...');
    this._writeResponseHead(context, res);
    return this._pipeStream(stream, res).
      catch(function(err) {
        error('error streaming image to response: %o', err);
        failResponse(res, err.message);
        res.end();
        return Promise.reject(err);
      });
  }

  _pipeStream(a,b) {
    return new Promise(function(resolve, reject) {
      let streamError = false;
      a.on('finish', function() {
          if (!streamError) { resolve(); }
        }).
        on('error', function(err) {
          streamError = true;
          reject(err);
          try { a.close(); } catch(e) {}
        });
      a.pipe(b);
    });
  }

  _cleanup(context) {
    if (context._cleanupFunctions) {
      for (let i = 0, len = context._cleanupFunctions.length; i < len; i++) {
        let func = context._cleanupFunctions[0];
        log('performing cleanup: %o', func);
        try {
          func();
          log('cleanup completed');
        } catch (err) {
          error('error in cleanup function: %o', err);
        }
      }
    }
  }

}

module.exports = Processor;


text:
British officials admonish Trump after 'unhelpful' terror tweets
Exactly one month ago, Donald Trump held a bizarre press conference in which he tried to defend his response to racist violence in Charlottesville. Asked why it took so long for him to denounce white supremacists, the president had an explanation in mind.
"I wanted to make sure, unlike most politicians, that what I said was correct, not make a quick statement," Trump said, adding, "[Y]ou don't make statements that direct unless you know the facts. It takes a little while to get the facts…. I don't want to go quickly and just make a statement for the sake of making a political statement. I want to know the facts…. When I make a statement, I like to be correct. I want the facts…. This event just happened. Before I make a statement, I need the facts."
And yet, there was Trump this morning, responding with lightning speed this morning to the detonation of a device aboard a London subway train, tweeting, "Another attack in London by a loser terrorist. These are sick and demented people who were in the sights of Scotland Yard. Must be proactive!" Whether the president had Scotland Yard's permission to share those details is unclear. (The message also implicitly suggested law enforcement officials in the U.K. hadn't done enough.)
The American president quickly added, in the hopes of exploiting the violence to advance his agenda, "The travel ban into the United States should be far larger, tougher and more specific – but stupidly, that would not be politically correct!" What he was proposing in practical terms was unclear.
Our allies were not impressed.
Britain's Prime Minister rebuked President Donald Trump Friday after he tweeted that "a loser terrorist" responsible for a subway train blast had been "in the sights" of London's Metropolitan Police.
Asked whether Trump knew something that the British public did not, PM Theresa May said: "I never think it's helpful for anybody to speculate on what is an ongoing investigation."
Her former chief of staff, Nick Timothy, went further, describing Trump's comment as "so unhelpful from leader of our ally and intelligence partner."
It'd be less jarring if this were the first time Trump responded badly to an attack in London, but it's not.
In early June, following a terrorist attack in London, Trump responded by talking about his Muslim ban, feuding needlessly with the city's mayor, and for some reason, throwing in a complaint about gun control.
In both instances, the American president reacted first and received detailed information second. Trump has obviously told a breathtaking number of lies, but perhaps the most ridiculous of all was his declaration, "I don't want to go quickly and just make a statement for the sake of making a political statement. I want to know the facts."
The MaddowBlog, Donald Trump, Great Britain, National Security, Terrorism and United Kingdom
Friday's Campaign Round-Up, 9.15.17
Friday's Mini-Report, 9.15.17


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AP. ® English Language and Composition. 2002 Free-Response Questions ... The following passage concludes an essay by Edward Abbey about Aravaipa Canyon in New .... technological innovation is a question with two possible answers.
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2002 AP® ENGLISH LANGUAGE AND COMPOSITION FREE-RESPONSE. QUESTIONS ... technological innovation is a question with two possible answers.


The phrase has never rang more true when it comes to cultural appropriation. In fact, according to Nielsen, 73% of Whites and 67% of Hispanics believe that African Americans influence mainstream culture. I mean I get it. Black culture and entertainment is fun, cool, fresh, stylish, has a beat, and is original. It even makes for a great Instagram selfie. Black issues? Not so much. However, oddly enough Black issues have been trending among the Black community long before anyone could put a hashtag on it. And that's one of the problems with culture appropriation – the cafeteria-style tactic some White people take to Blackness.
It's all blonde cornrow selfies and Kylie Jenner lip challenges until a Black person gets shot during a "routine" traffic stop. Then it's crickets. Where are those same people who take such pride in Black culture and even tweet about how dope the new Kendrick Lamar CD is during the recent onslaught of deaths that included: Sandra Bland, Freddie Gray, Eric Garner, the Emanuel Nine, Trayvon Martin, Michael Brown, Aiyana Jones, Rekia Boyd, Tamir Rice, and sadly others? I'm guessing they were at Whole Foods posting their kale salad lunches to Instagram. I understand that life goes on even in the light of tragedy, but usually when someone loses their life, condolences are in order. It's open season, and I've only been seeing one type of prey.
A major problem with cultural appropriation is that it doesn't provide appropriators with a full spectrum of experiences in relation to the culture that they are borrowing from. Appropriators are doing themselves a great disservice if they think the Black experience is just limited to hairstyles and hip-hop. In response to such madness, I decided to put together a list things White people really should be appropriating, so they can truly have a holistic, intimate grasp on Blackness. Now, I'm not suggesting that any of the below should happen to anyone. Marginalized or not, everyone deserves to have their basic human rights respected. However, if there was an alternate universe where White people could experience any of the below on a macro level, then I'm confident there'd be a lot more awareness and empathy to go around – which is extremely rare in this day and age. So, in no particular order, here are 31 things White people should be culturally appropriating. You're welcome and appropriate away!
Terrence Chappell surfaced on Chicago's media scene as UR Chicago Magazine Online's fashion editor. Since then, he has worked and contributed to various media outlets such as Michigan Ave. Magazine, CS Magazine, and The Men's Book. Currently, Terrence serves as the editor-at-large for ChicagoPride.com, the city's largest LGBT entertainment and news website where he writes "Chappell Confidential," a nightlife and society column. Terrence also heads "Chappell on Community," the site's newest editorial monthly series that profiles the LGBT community's most innovative leaders.


text:
History of LoRa
LoRa got started in Grenoble, France in 2009 through the collaboration of two friends who wanted to develop a long range radio that consumed small amounts of power. Along with another collaborator they formed a company called Cycleo who set out to develop LoRa, which is simply short for 'Long Range'. Their intention was to develop and sell their designs to chip manufacturers, their target market being the utility metering industry. In 2012 Cycleo were acquired by Semtech, a US manufacturer of semiconductors. In collaboration with the founders of Cycleo, Semtech produced two transceiver chips for use in user equipment (IoT) devices and others for network gateways and routers. Along with the hardware, they created a proprietary networking protocol, defining the mechanisms by which devices talk to the network and how radio channels are managed. In 2015 the LoRa Alliance was founded and the network protocol was named LoRaWAN. The goals of the LoRa Alliance are to "support and promote the global adoption of LoRaWAN standards by ensuring interoperability of all LoRaWAN products and technologies."(source, LoRa Alliance).
LoRa Alliance members include Cisco, IBM, Amazon, BT, Orange, KPN and NTT.
Whereas Sigfox build only public networks, either themselves or through licensees, the LoRa Alliance strategy is to provide a standardised set of networking equipment with which both public and private networks can be built.
As of March 2021 there were some 178 million devices connected to over 140 public and private LoRa networks globally.
Long Range Technology
LoRa networks use the same unlicensed frequency bands as Sigfox, these are based around 868 MHz in Europe and 915 MHz in North America. LoRa uses these frequencies in a different way to the Sigfox UNB (Ultra Narrow Band) approach where devices send and receive on a narrow 100 Hz wide channel. Messages on LoRa networks use a spread spectrum modulation technique known as CSS (Chirp Spread Spectrum) operating in bandwidth channels of 125 kHz or 500 kHz for uplink messages and 500 kHz for downlink. CSS modulation allows for higher bit rates than Sigfox, typically 25 kbps – 50 kbps, but slightly lower than those for NB-IoT. LoRa networks are built in a star topology with customer devices communicating with an intermediary device called a gateway which concentrates user traffic for transmission to the network server. LoRa gateways are not expensive, typically £1k - £2K for a carrier-grade device designed to operate outdoors (IP67 rated) on the roof of a building. A LoRa gateway working in an office environment can be purchased for around £100. The range of a gateway is 2km-5km (urban) and up to 15 km (suburban), slightly less than Sigfox in an urban environment and about half the range of Sigfox for suburban locations. In that respect LoRa has a disadvantage when compared to Sigfox, although the low cost of the gateways allows for more numerous deployments of them. LoRa operates fully bi-directionally unlike Sigfox which is constrained in its network to device capability.
There can be multiple LoRa networks within a city, both public and private, so to build a private LoRa network within a building is relatively inexpensive, although unlike a public network the private network owner has to fund the operating costs. Unlike Sigfox networks the actual data rates on LoRa depends on distance between the end-point device and the gateway.
In terms of security, LoRa supports end to end encryption using the AES128 algorithm.
Benefits of Using LoRa and the LoRa Ecosystem
The LoRa Alliance Catalogue gives customers a big range of IoT devices to choose from.
Standardisation around the Semtech SX127x series chipsets has allowed Alliance members to build their devices around those, with certainty of connection to any LoRa network, public or private. Although cheaper to build than cellular NB-IoT hardware, at around $10 they are more expensive than a Sigfox module which is typically $5. LoRa gives the benefit of low cost connectivity with long range when compared to technologies such as Wifi and Zigbee, excellent in-building penetration and very long battery life. Mobile network operators such as Orange, Swisscom, KPN, Proximus and SK Telecom have all deployed LoRa public networks alongside their cellular IoT offerings. Application developers considering using LoRa for their IoT deployment can download the LoRa specification documents.
Getting on Board – Device Provisioning
Public LoRa networks provide full instructions for manual onboarding of IoT devices.
Here are the procedures for automated onboarding of LoRa devices in volume using QR codes
Typical LoRa Applications
Controlled access to waste recycling facilities Public and employee safety. Iioote and Rambo AB
Fuel Tank monitoring Optimised delivery and collection routes, saving time and money. FULLUP
Supply Chain & Logistics 40% improvement in ETA, 30% reduction in Opex. SmartMakers
Smart Parking Reduced driving time, Co2 reductions, improved capacity utilisation. Sensors connected to a mobile phone application route drivers to a vacant parking space. Smart Parking Systems
Battery life on LoRa networks is not so predictable as it is for Sigfox where the slow transmit rate (100 bps) within the duty cycle rules in Europe limit the number of messages to 140 per day. The higher speeds possible with LoRa mean that the device can be active less of the time while sending its message, so in practical terms the battery life for a typical IoT application requiring power autonomy is similar to that of Sigfox.
Messages/Day
Expected Battery Life*
Alarm Notifications 1-5 10 years
Low Use Sensors 5-25 7 years
High Use Sensors 25-100 5 years
Location/Tracking >100 2 years
*Using same size battery in each application case. When deploying an IoT sensor device the battery can be the most costly component. Simply using a bigger battery can extend battery life but make the total cost of deployment prohibitive. The assumption here based on typical use cases is a battery of 3v and 1,000 mAh capacity.
In terms of the number of IoT devices connected, LoRa is the most successful unlicensed wireless technology. However, a large proportion of connected devices are on private networks. The number connected on publicly available networks is not clear, although LoRa Alliance member The Things Industries report 55% of gateway shipments in 2020 were to public network operators, indicating that around half the claimed 178 million connections are from paying customers.
For the customers wanting to connect their devices rather than build and operate their own network, you can find all the information on public LoRa networks.
Whereas Sigfox is more limited in its use cases and has positioned itself as complimentary to cellular networks the higher data rates of LoRa puts the technology into direct competition with the mobile operators as they roll out NB-IoT. Most use cases for LoRa are within the scope of NB-IoT which offers lower latency, better security and slightly higher data rates than LoRa. Where very low power consumption is the most important criteria LoRa is a better option.
In January 2020 the LoRa Alliance announced 2.4 GHz LoRa, a technology competing with Wifi but with a range of up to 300 metres in free space. Semtech transceivers were already available and ecosystem partners have incorporated 2.4 GHz cards into their sub GHz gateways. This technology allows location based services with a sub 5 metre accuracy to be deployed on LoRa networks, the advantage over traditional GNSS (satellite) being much lower power consumption and simpler, cheaper electronics. This development opens up a big market for tracking packages, pallets or any goods in transit where no power supply is available.
The momentum LoRa has gained over the last 5 years suggests it is here to stay and will remain a credible technology for IoT connectivity.


Someone who thinks the stock market will drop. A bear market is a falling market. The opposite of a bear is a bull and the opposite of a bear market is a bull market. For information on the derivation of bear and bull, go to Investment Trivia.