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Risk factors for mortality in patients with acute kidney injury and hypotension treated with continuous veno-venous hemodiafiltration
Kidney Res Clin Pract. 2012;31(4):214-218
Kidney Res Clin PractJournal ArchiveKidney Res Clin Pract. 2012;31(4)
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Publication date (electronic) : 2012 October 05
doi : https://doi.org/10.1016/j.krcp.2012.09.005
In Myung Oh, Jang Han Lee, Kyoung Hwa Yoo, Ji Eun Park, Dong Hyun Oh, Mi Jung Kim, Seung Hea Ha, Gi Jong Lee, Jung Hee Kim, Yoon Chul Jung
Department of Internal Medicine, Bundang Jesaeng General Hospital, Sungnam, Korea
⁎Corresponding author. Division of Nephrology, Department of Internal Medicine, Bundang Jesaeng General Hospital 255-2 Seohyun-dong, Bundang-gu, Sungnam-si, Gyungki-do 463-774, Korea. j580309@dreamwiz.com
Received 2012 April 12; Revised 2012 June 20; Accepted 2012 July 31.
Continuous veno-venous hemodiafiltration (CVVHDF) is a preferred treatment modality in hemodynamically unstable acute kidney injury (AKI) patients, because it has advantages over intermittent dialysis in terms of hemodynamic stability. However, this patient group still shows a significantly high mortality rate. To aid in the management of these high-risk patients, we evaluated the risk factors for mortality in CVVHDF-treated hypotensive AKI patients.
We studied 67 patients with AKI and hypotension who were treated with CVVHDF from February 2008 to August 2010. We reviewed patient characteristics and laboratory parameters to evaluate the risk factors for 90-day mortality.
Of the 67 enrolled patients (male:female=42:25; mean age=69±14 years), 18 (27%) survived until 90 days after the initiation of CVVHDF. There was no significant difference in survival rates according to the etiology of AKI [hypovolemic shock 2/10 (20%), cardiogenic shock 4/20 (20%), septic shock 12/37 (32%)]. Univariate analysis did show significant differences between survivors and non-survivors in the frequency of ventilator use (44% vs. 76%, respectively; P=0.02), APACHE II score (29±7 vs. 34±7, respectively; P=0.01), SOFA score (11±4 vs. 13±4, respectively; P=0.03), blood pH (7.3±0.1 vs. 7.2±0.1, respectively; P=0.03), and rate of urine output <500 mL for 12 hours (50% vs. 80%, respectively; P=0.03). A multivariate Cox proportional hazards model showed that a urine output<500 mL for 12 hours was the only significant risk factor for 90-day mortality following CVVHDF treatment (odds ratio=2.1, confidence interval=1.01–4.4, P=0.048).
A urine output<500 mL for 12 hours before the initiation of CVVHDF is an independent risk factor for 90-day mortality in hypotensive AKI patients treated with CVVHDF.
Keywords: Acute kidney injury; Hypotension; Mortality; Renal replacement therapy
Renal replacement therapy (RRT) is required in 5–6% of critically ill patients, and acute kidney injury (AKI) requiring dialysis, is associated with especially high mortality rates of 50–80% [1]. AKI patients requiring RRT also have a high frequency of multiorgan failure or hemodynamic instability [2].
Continuous renal replacement therapy (CRRT) was proposed as an alternative to intermittent dialysis in hemodynamically unstable patients, because it is better tolerated, due to the gradual removal of fluid and uremic toxins [3], [4], [5].
Although previous studies have identified several prognostic factors for mortality associated with CRRT, such as sepsis, higher APACHE II scores, oliguric AKI, the presence of coma, higher SOFA scores, and the need for mechanical ventilation in critically ill patients undergoing CRRT, each study found different results according to the indication for CRRT and the severity of the disease [6], [7], [8], [9], [10], [11]. Therefore, the prognostic factors for patients requiring CRRT still remain somewhat obscure.
Confused classification of patients with regard to the severity and features of their disease, may lead to difficulties in identifying the factors affecting the prognosis of CRRT. Nevertheless, we attempted to assess the characteristics of patients undergoing CRRT treatment. Therefore, this study was focused on AKI patients with hemodynamic instability undergoing CRRT. We evaluated the risk factors for mortality within 90 days after the initiation of CRRT in patients with AKI and hypotension.
The inclusion criteria were a clinical diagnosis of AKI and hypotension. AKI was defined by a twofold increase in serum creatinine, a decrease in estimated glomerular filtration rate (GFR) of >50%, or a reduction in urine output <0.5 mL/kg/hour for 12 hours [12]. Hypotension was defined by an initial mean arterial pressure <60 mmHg, or the use of vasopressors such as dopamine or norepinephrine, to maintain systolic blood pressure >100 mmHg when continuous veno-venous hemodiafiltration (CVVHDF) was started. A total of 108 patients were treated with CVVHDF in the medical-surgical intensive care unit from February 2008 to August 2010. Normotensive patients and those who had end-stage renal disease or malignancy were excluded. We identified 67 patients who had AKI and hypotension at the initiation of CVVHDF. All enrolled patients were followed for >90 days.
Treatment modality
CVVHDF was performed with the multiFiltrate (Fresenius Medical Care, Fürth, Germany) and the Ultraflux AV600S dialyzer (surface area=1.4 m2) (Fresenius Medical Care, St. Wendel, Germany) through double-lumen catheters inserted into the internal jugular or femoral vein. Blood flow rates were maintained between 100 and 150 mL/minute and the predilution replacement method was used. Anticoagulation was performed with heparin or nafamostat.
Investigated parameters
Demographic data including age, sex, diabetes mellitus, and hypertension, and clinical parameters such as duration of hospitalization, ventilator use, cause of hypotension, urine output before the initiation of CVVHDF, previous surgical intervention, and type of anticoagulation, were collected. Laboratory parameters, including C-reactive protein, blood urea nitrogen, serum creatinine, white blood cell count, hemoglobin, blood pH and chest radiographic information were also gathered at the initiation of CVVHDF.
SOFA scores and APACHE II scores were employed to evaluate the severity of disease.
Patients were assigned to two groups [RIFLE-I (injury) and RIFLE-F (failure)] with increasing severity of RIFLE stage. We compared demographic, clinical, and laboratory parameters as well as mortality between these two groups.
We also compared demographic, clinical, and laboratory parameters between the survivors and non-survivors to identify the risk factors for mortality in hypotensive AKI patients treated with CVVHDF.
Data are presented as mean (standard deviation) or median and range. Between-group analyses were made using unpaired Student t tests. Categorical variables were analyzed using the Chi-square test or Fisher's exact test. Cox regression analysis was used to show the adjusted odds ratio of investigated parameters. Variables with a P<0.10 in univariate analyses were included for multivariate analysis. Hazard ratios with their corresponding 95% confidence intervals are reported. A P<0.05 was considered statistically significant.
Baseline data and severity of illness
Basic demographic data are shown in Table 1.
Baseline characteristics of hypotensive acute kidney injury patients treated with continuous veno-venous hemodiafiltration (CVVHDF)
A total of 67 patients were included in this study. The mean age of the patients was 69±14 years, and 42/67 (62%) were male. The most common comorbidity was hypertension (47%), followed by diabetes mellitus (31%). The median length of hospital stay was 13±18 days. Twenty-two out of 67 (32%) patients had undergone surgical intervention within the previous month. Forty-five out of 67 (66%) patients received ventilator care and 36/67 (53%) patients showed pulmonary edema on chest radiography before the initiation of CVVHDF. Oliguria, defined by a urine output<500 mL within 12 hours before the initiation of CVVHDF, occurred in 48/67 (71%) patients. Thirty-four out of 67 (51%) patients received loop diuretics.
The most common cause of hypotension was septic shock (37/67, 55%), followed by cardiogenic shock (20/67, 30%) and hypovolemic shock (10/67, 15%). The mean APACHE II score was 32±7 and mean SOFA score was 13±4. Mean values for blood urea nitrogen and serum creatinine were 62±34 mg/dL and 3±4 mg/dL, respectively.
In univariate analysis, the rate of oliguria before the initiation of CVVHDF was significantly higher in the RIFLE-F group than in the RIFLE-I group (81% vs. 58%, respectively; P=0.04). There was no difference in 90-day mortality between the two groups (73% vs. 73%, respectively; P=0.99).
Outcomes and predictors of survival
The mortality rate of the hypotensive AKI patients who received CVVHDF was 73% (49/67).
Table 2 shows univariate comparisons of clinical characteristics and laboratory findings between survivors and nonsurvivors.
Univariate comparisons of demographic and laboratory findings between survivors and non-survivors in hypotensive acute kidney injury patients treated with continuous veno-venous hemodiafiltration (CVVHDF)
There were no significant differences in survival rates according to the cause of shock; septic shock (12/37, 32%), cardiogenic shock (4/20, 20%), hypovolemic shock (2/10, 20%).
In univariate analysis, the rate of use of mechanical ventilation was significantly higher for the non-survivor group than the survivor group (76% vs. 44%, respectively; P=0.02). Oliguria before the initiation of CVVHDF occurred significantly more often in the non-survivor group than in the survivor group (80% vs. 50%, respectively; P=0.03). The mean APACHE II score was significantly higher for the non-survivor group than for the survivor group (34±7 vs. 29±7, respectively; P=0.01), as well as the SOFA score (13±4 vs. 11±4, respectively; P=0.03).
Multivariate Cox proportional hazards analysis showed that a urine output<500 mL for 12 hours before the initiation of CVVHDF was the only significant risk factor for 90-day mortality (odds ratio=2.1, confidence interval=1.01–4.4, P=0.048) (Table 3). Comorbidities, cause of shock, clinical severity scores, degree of metabolic acidosis, and type of anticoagulation were not found to contribute to the mortality rate.
Multivariate Cox proportional hazards ratio of 90-day mortality after the initiation of continuous veno-venous hemodiafiltration (CVVHDF)
This study shows that a decreased urine output <500 mL for 12 h before the initiation of CVVHDF, is an independent risk factor for 90-day mortality. This result suggests that early initiation of CVVHDF may be associated with improved survival and that a decrease in urine output could be a parameter used to determine the time of CVVHDF initiation in hemodynamically unstable patients.
Several previous trials have investigated the prognostic factors for mortality of patients undergoing CRRT; these studies found different prognostic factors [8], [10], [11]. One study showed that metabolic acidosis and earlier initiation of CRRT were associated with the survival of patients with AKI receiving CRRT [10]. In another study, the independent prognostic factor for mortality in AKI patients treated with CRRT was found to be the APACHE II score [7]. In the current study, univariate analysis showed that arterial pH and APACHE II score were significantly different between survivors and non-survivors. However, multivariate analysis did not show that these factors were significant predictors of mortality.
Bouman et al. [13] defined early hemofiltration as treatment started when urine output is decreased <30 mL/hour for over 6 hours and reported that early dialysis did not affect mortality. Bae et al. [11] reported that lower mean arterial blood pressure and lower serum bicarbonate levels measured the day after CRRT may predict a poor prognosis. These conflicting results might be caused by differences in disease severity and study populations, because we examined prognostic factors in a group with more severe disease and hemodynamic instability.
Our study indicates that urine output may be an important parameter for the determination of the optimal time for CRRT. Fluctuations in blood pressure affect renal blood flow and GFR due to renal autoregulation [14]. A marked reduction in renal perfusion may overwhelm autoregulation and precipitate an acute fall in GFR.
After Bellomo et al. [12] first suggested the RIFLE criteria for the classification of the severity of AKI and patient prognosis, many attempts have been made to prove the usefulness of these criteria. Studies report that when CRRT is applied at the "injury stage" when severity is relatively low, the mortality of patients decreases [15], [16], [17], [18], [19]. In addition, a recent domestic study also showed that the 90-day mortality rate was significantly lower in patients who received CRRT in the injury stage of the RIFLE criteria, when compared with those in the failure or loss stages [20]. However, the current study showed that there was no difference in 90-day mortality between the RIFLE-I group and the RIFLE-F group. Our results suggest that starting treatment prior to the RIFLE-I stage may represent the optimal timing for CRRT. Further studies using the RIFLE criteria as a prognostic factor are needed to support this idea.
There are some limitations to our study. Firstly, it is a retrospective, observational, single-center study, with all the inherent limitations of such investigations. Further, our study could not rule out the selection bias included in variable clinical conditions and the size of the study group was relatively small. Therefore, further prospective, multiple-center, large-group studies will be needed to clarify the factors affecting prognosis in hemodynamically unstable AKI patients receiving CRRT.
In conclusion, a decreased urine output <500 mL for 12 h before the initiation of CVVHDF, is an independent prognostic factor for mortality in AKI patients with hemodynamic instability treated with CVVHDF. This result suggests that early initiation of CRRT before a decrease in urine output is beneficial.
The authors declare there is no conflict of interest.
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Article information Continued
© 2012. The Korean Society of Nephrology. Published by Elsevier.
(CC BY-NC-ND, http://creativecommons.org/licenses/by-nc-nd/4.0/) :
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
All patients (n=67)
RIFLE-I (n=26, 39%)
RIFLE-F (n=41, 61%)
Demographic characteristics
Age (y) 69±14 66±17 71±12 NS
Male, n (%) 42 (62%) 16 (62%) 26 (62%) NS
Death, n (%) 49 (73%) 19 (73%) 30 (73%) NS
Diabetes mellitus, n (%) 21 (31%) 5 (19.2%) 16 (39%) NS
Hypertension, n (%) 32 (47%) 11 (42%) 21 (51%) NS
Clinical parameters
Duration of hospitalization (d) 13±18 13±15 14±21 NS
Previous surgical intervention, n (%) 22 (32%) 13 (50%) 9 (22%) NS
Ventilator use, n (%) 45 (66%) 16 (62%) 29 (73%) NS
Pulmonary edema on chest x-ray 36 (53%) 15 (58%) 21 (51%) NS
Urine output<500 mL for 12 h before initiation of CVVHDF, n (%) 48 (71%) 15 (58%) 33 (81%) 0.04
Loop diuretic therapy, n (%) 34 (51%) 17 (65%) 17 (41%) NS
Cause of shock NS
Septic shock, n (%) 37 (55%) 14 (54%) 25 (61%)
Cardiogenic shock, n (%) 20 (30%) 8 (31%) 10 (24%)
Hypovolemic shock, n (%) 10 (15%) 4 (15%) 6 (15%)
Anticoagulation NS
Nafamostat, n (%) 21 (31%) 10 (39%) 13 (32%)
Heparin, n (%) 26 (39%) 9 (35%) 17 (42%)
No anticoagulation, n (%) 20 (30%) 7 (27%) 11 (27%)
Severity score
APACHE II score 32±7 32±7 33±7 NS
SOFA score 13±4 14±3 12±4 NS
Laboratory findings on initiation of CVVHDF
BUN (mg/dL) 62±34 55±31 67±35 NS
Serum creatinine (mg/dL) 3±4 3±1 4±4 0.02
C-reactive protein (mg/dL) 9±7 10±8 8±7 NS
pH 7.3±0.1 7.3±0.1 7.2±0.1 NS
WBC (/mm3) 14,000±7,000 16,000±8,000 13,000±7,000 NS
Hemoglobin (g/dL) 11±3 11±2 10±3 NS
Platelets (×103/mm3) 140±70 130±70 150±110 NS
Survivors (n=18)
Non-survivors (n=49)
Age (y) 65±17 70±13 NS
Male, n (%) 12 (67%) 30 (63%) NS
Diabetes mellitus, n (%) 7 (39%) 14 (29%) NS
Hypertension, n (%) 9 (50%) 23 (47%) NS
Duration of hospitalization, (d) 10±15 15±19 NS
Previous surgical intervention, n (%) 4 (22%) 18 (38%) NS
Ventilator use, n (%) 8 (44%) 37 (76%) 0.02
Pulmonary edema on chest x-ray, n (%) 6 (33%) 30 (61%) 0.06
Urine output<500 mL for 12 h before initiation of CVVHDF, n (%) 9 (50%) 39 (80%) 0.03
Loop diuretic therapy, n (%) 8 (44%) 26 (53%) NS
Cause of shock
Septic shock, n (%) 12 (67%) 25 (51%) NS
Cardiogenic shock, n (%) 4 (22%) 16 (33%) NS
Hypovolemic shock, n (%) 2 (11%) 8 (16%) NS
Nafamostat, n (%) 3 (17%) 18 (37%) NS
Heparin, n (%) 6 (33%) 20 (41%) NS
No anticoagulation, n (%) 9 (50%) 11 (22%) NS
APACHE II score 29±7 34±7 0.01
SOFA score 11±4 13±4 0.03
BUN (mg/dL) 64±31 62±35 NS
Creatinine (mg/dL) 4±2 3±3 NS
C-reactive protein (mg/dL) 6±7 9±7 0.1
pH 7.3±0.1 7.2±0.1 0.03
WBC (/mm3) 14,000±7,000 14,000±7,000 NS
Hemoglobin (g/dL) 11±3 10±3 NS
Platelets (×103/mm3) 160±120 120±80 NS
SOFA score 1.1 0.99–1.18 0.1
Urine output<500 mL for 12 h before initiation of CVVHDF 2.1 1.01–4.4 0.048


text:
Author Salman Rushdie blind in one eye after attack
Author Salman Rushdie (Reuters)
Author Salman Rushdie has lost vision in one eye and the use of one hand following his stabbing in New York in August, his agent says.
"He has about 15 more wounds in his chest," Andrew Wylie, a New York-based agent, also told Spain's El País newspaper. "It was a brutal attack."
Wylie said he could not disclose the novelist's whereabouts. The assault occurred at an event in New York state.
Rushdie has long faced death threats for his 1988 novel The Satanic Verses.
Some Muslims regard the book as blasphemous. The man charged over the attack, US-born Hadi Matar, 24, has pleaded not guilty to attempted murder.
"He's lost the sight of one eye," Wylie said in his interview with El País. "He had three serious wounds in his neck. One hand is incapacitated because the nerves in his arm were cut."
Asked if the author was still in hospital, Wylie replied: "I can't give any information about his whereabouts. He's going to live… That's the more important thing."
The attack took place at the Chautauqua Institution in New York State on 12 August. Rushdie was about to give a speech about how the US has served as a haven for writers.
The novelist was forced into hiding for nearly 10 years after The Satanic Verses was published. Many Muslims reacted with fury to it, arguing that the portrayal of the Prophet Muhammad insulted their faith.
He faced death threats and the then-Iranian leader, Ayatollah Ruhollah Khomeini, issued a fatwa – or decree – calling for Rushdie's assassination, placing a $3m bounty on the author's head.
The fatwa remains active, and although Iran's government has distanced itself from Khomeini's decree, a quasi-official Iranian religious foundation added a further $500 000 to the reward in 2012.
Wylie told El País that he had discussed such threats with Rushdie over the years. "The principal danger that he faced so many years after the fatwa was imposed is from a random person coming out of nowhere and attacking.
"So you can't protect against that, because it's totally unexpected and illogical. It was like John Lennon's murder."
Rushdie was born in India in 1947. He was sent to boarding school in England before studying at the University of Cambridge. In 2007, he was knighted for services to literature.
There has been an outpouring of support for him, with the attack widely condemned as an assault on freedom of expression.
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redpajama_set_name: RedPajamaCommonCrawl


text:
Nebraska executes inmate using Fentanyl
October 17, 2018 by lloyd payne
Despite being sued by a pharmaceutical company for alleged unauthorized use, the state of Nebraska was successful in executing a prisoner on death row using the addictive drug fentanyl, according to NPR News. Robert Dunham, head of the Death Penalty Information Center, believed the use of fentanyl—the first execution in the country using the chemical—was unusual.
"It's somewhat ironic that at the same time the Justice Department and states are talking about how dangerous fentanyl is and how it's created a national public health emergency that states are now turning to it as a supposedly safe way of killing prisoners," Dunham said told NPR. Convicted of murder in 1980, Carey Dean Moore was sentenced to death and did not put up a legal fight against being injected with a lethal dose of the deadly opiate.
Oklahoma Execution
But Fresenius Kabi, a German pharmaceutical company, challenged Moore's execution in federal court according to NPR News.
Fresenius Kabi are the makers of potassium chloride and cisatracurium besylate, two of the four drugs used in the state's execution cocktail, and filed a suit requesting that a temporary restraining order be granted on the grounds that the state of Nebraska may have purchased those drugs illegally.
The company commented that its drugs are only sold by authorized dealers who "contractually agreed to particular constraints, such as excluding sale to federal or state incarceration facilities."
Nebraska has been vocal about the debate over the use of the two drugs in Moore's execution. The state said after contacting a number of potential suppliers and six different states, the drug was supplied by a licensed pharmacy in the United States. Nebraska authorities claim that the drug was not obtained by fraud, deceit or misrepresentation.
Judge Richard Kopf denied the restraining order. He stated the claim that the drugs' use would cause the company "irreparable injury" was "far too speculative," allowing the state of Nebraska to complete the execution.
NET News reported that there have also been concerns by death-penalty abolitionists about the drug cisatracurium besylate, which causes paralysis.
"If in tortuous pain the paralysis would make the subject unable to respond," NET News summarized.
Moore was given the first drug at 10:24 a.m. and pronounced dead by 10:47 a.m., according to the Nebraska Department of Correctional Services.
The Associated Press reported that while on the gurney, Moore turned his head and mouthed several words to his family, including "I love you."
His execution was under heavy scrutiny by the ACLU Nebraska chapter.
"This execution of Carey Dean Moore does not comport with Nebraska's proud tradition of open government," director Danielle Conrad said to NPR. She also said it stood as the most dark chapter in Nebraska's troubled history with the death penalty. The state had not executed an inmate since 1997.
PPI's "Correctional Control: Incarceration and Supervision by State" is the first report to aggregate data on all types of correctional control nationwide.
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Tennessee schedules three executions
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Filed Under: Death Penalty Tagged With: execution methods, fentanyl, Nebraska, prison executions


text:
1.1 By 2030, eradicate extreme poverty for all people everywhere, currently measured as people living on less than $1.25 a day
1.2 By 2030, reduce at least by half the proportion of men, women and children of all ages living in poverty in all its dimensions according to national definitions
1.3 Implement nationally appropriate social protection systems and measures for all, including floors, and by 2030 achieve substantial coverage of the poor and the vulnerable
1.4 By 2030, ensure that all men and women, in particular the poor and the vulnerable, have equal rights to economic resources, as well as access to basic services, ownership and control over land and other forms of property, inheritance, natural resources, appropriate new technology and financial services, including microfinance
1.5 By 2030, build the resilience of the poor and those in vulnerable situations and reduce their exposure and vulnerability to climate-related extreme events and other economic, social and environmental shocks and disasters
1.A Ensure significant mobilization of resources from a variety of sources, including through enhanced development cooperation, in order to provide adequate and predictable means for developing countries, in particular least developed countries, to implement programmes and policies to end poverty in all its dimensions
1.B Create sound policy frameworks at the national, regional and international levels, based on pro-poor and gender-sensitive development strategies, to support accelerated investment in poverty eradication actions


text:
The War on Refusing Drugs
A middle school girl is suspended by her school after giving back the pills her friend gave her.
The girl did not bring the prescription drug to her Jeffersonville, IN school, nor did she take it, but she admits that she touched it and in Greater Clark County Schools that is drug possession.
Rachael Greer said it happened on Feb. 23 during fifth period gym class at River Valley Middle School when a girl walked into the locker room with a bag of pills.
"She was talking to another girl and me about them and she put one in my hand and I was like, 'I don't want this,' so I put it back in the bag and I went to gym class," said Rachael.
The pills were the prescription ADHD drug, Adderall. Patty Greer, Rachael's mother, said she and her husband are proud of their daughter for turning down drugs, just like she's been taught for years by DARE (Drug Abuse Resistance Education) instructors at school.
According to Greater Clark County Schools district policy, even a touch equals drug possession and a one week suspension.
The district says as far as it's concern, that counts as possession. The article claims "District officials say if they're not strict about drug policies no one will take them seriously." Oh, I don't know if they have to worry about that. And if I'm the judge in the inevitable lawsuit, my first question for the district's attorney is "what if the girl just had a pill thrown at her? What if it was tossed at her and she reflexively caught it and dropped it?"
Kind of extreme examples -- but then, under normal circumstances so is the case of the girl who is handed the pill and immediately gave it back. What we have is a situation where the school district officials clearly are less intelligent than the students they're overseeing.
Labels: drugs, law, schools
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Welcome to the Branding Iron Roadhouse, Main Street, Lime Ridge, WI, established 2011. The Branding Iron is a true farm‐to‐fork restaurant serving delicious food, cooked to order, and made from locally grown beef and other locally produced products. Your traditional Wisconsin Friday Night Fish Fry comes hot from the fryer to your plate, and, if you want a medium‐rare burger, just ask!
We use our very own Fearing Angus Beef in our burgers. Fearing Angus Beef is pasture‐raised, hormone‐free, and antibiotic free. Our cheese comes from world‐class neighbors, Carr Valley Cheese. The sandwich buns are from Esther's Bakery, a WI State inspected Amish bakery just down the road, and Reedsburg's Viking Village Bakery bakes the rolls for our Friday Night Fish Fry. We buy our seasonal produce from local farmers including Weston School District's Garden CSA Program and Orange Cat Organic Farm CSA Program.
At the Branding Iron Roadhouse you will find six micro‐brews on tap with many Wisconsin brewed beers by the bottle. Check out our beer list; we are certain you will find something you like. Our Purple Feet wine advisor has never let us down; we offer an excellent selection of premium wine.
Mark your calendar for our special monthly menus. On the first and third Wednesdays of the month, we serve Wood‐fired Oven Pizza. On the second Thursday, we have an Original‐Works Open Mic hosted by the One and Only Driftless Jimmy. On Friday night, we hold a traditional Wisconsin Fish Fry with beer‐batter featuring Wisconsin micro‐brewed beer. On the last Saturday of the month is our BBQ Smoke Night, where Steve breaks out the smoker for an unforgettable dining experience. And, once a month or so, we offer a Visiting Culinarian Dinner — we invite extraordinary Foodies to the Branding Iron to create delicious meals. Email us or Call us for Reservations!
Thank you for stopping in! Steve and I love living in the country. We do our best to live sustainably and we work with our neighbors so they can do the same. Please know that we welcome your suggestions and requests!
For more information about the Branding Iron Roadhouse, please visit our website, www.brandingironrh.com. Please feel free to sign up for our email list — Just enter your email address on the brandingironrh.com webpage or on the Facebook form link. You can also like us on facebook for news, events and specials!


Valentine's Day is perhaps the biggest coffee marketing opportunity between New Year's and Memorial Day. Economist predict Valentine's Day spending to reach $20 billion this year, with average spending topping 2015's high of $142 per person, according to the National Retail Federation. Here are seven easy marketing ideas that will help your store get in on Valentine's Day revenues this year.
From a French Kiss Latte to a Love Potion Frapp, adding just one holiday LTO can boost sales. That's because research finds that LTOs are a constant draw. Technomics reports that nearly half of all consumers try LTOs every month, and that percentage increases with Millennials and Pos-Millennials whose wallets are activated by adventure. Click here for a few LTO ideas from the baristas at Stockton Graham & Co.
Flameless votive candles. Fresh flowers. Classical music. Starlight mints. It doesn't take much to add a hint of romance to your coffee shop. Draw hearts on your chalk board. Or better yet, put a few felt tip pens near the register and ask your staff to draw simple hearts on each customer's paper coffee cup, Kraft bag or receipt.
A heart is perhaps the easiest-to-learn design in latte art. Taking two extra seconds to craft a heart on your lattes during Valentine's Day is the barista's equivalent to a chef's artful plating—it not only demonstrates that a barista cares about the drink but it also signals that your store cares about the customer's experience. This 2-minute video from Michael, the passionate coffee lover behind Barista Next Door, will have you and your baristas slinging hearts in no time.
Mid-January is not too early to start posting flyers and talking to customers about Valentine's Day at your store. If you will have special LTOs, then definitely start announcing them by February 1. This will give you enough time to develop marketing momentum and word-of-mouth around your offers.
Offer 4oz samples of holiday-inspired menu items to customers who make purchases of non-holiday coffee, tea, chai or sweets. Then ask for their feedback. This will allow you to perfect the flavors on your Valentine's Day menu and help you hone your marketing message and your recipe. It'll also give staff and customers something exciting to look forward to!
Although customers view Valentine's Day as an opportunity to splurge a bit on themselves and their loved ones, over-priced menu items are a turn off. Sure, you can probably get a 10% up-charge for holiday-themed beverages and desserts—just be sure to justify this with great taste, superb service and a warm, inviting atmosphere.
One of the biggest food trends in 2016 will be "clean" foods, which contain simple and unprocessed nutrition. Think about adding a whole fruit strawberry smoothie to your menu; add a few heart-shaped ice cubes to a cup of milk for the kids or to a My Fuzzy Valentine (pink grapefruit or blood orange and seltzer) beverage for health-conscious adults.
Feel free to reach out to our Customer Care Associates at 800 835 5943 for more information on making Valentine's Day a success for your business.
This entry was posted in Blog and tagged barista, Barista Next Door, Coffee, coffee shop, latte art, LTOs, marketing ideas, National Federation of Retailers, raleigh coffee roasting company, revenue ideas, Technometrics, Technomics, valentine's day by Stockton Graham. Bookmark the permalink.


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Q: How do I access the private IP? I am in a college that employs private IP addressing scheme. Different parts of the college have been allotted separate private IPs. Is it possible that I can access the private IP of other parts of the college. Manually setting the IP results in no connection. Also I am using an HTTP proxy. Any help ?

A:
I am in a college that employs private IP addressing scheme.

You can read Address Allocation for Private Internets for more detail about this;
roughly summarized, they are in one of the following ranges:

*

*192.168.0.0 - 192.168.255.255

*172.16.0.0 - 172.31.255.255

*10.0.0.0 - 10.255.255.255

Different parts of the college have been allotted separate private IPs.

This can be done by the means of

*

*subnetwork (separates the addresses)

*virtual LANs (separates the physical traffic)

Is it possible that I can access the private IP of other parts of the college.

This depends on how the subnetworks, VLANs and routing is set up in your gateway.

Manually setting the IP results in no connection. Also I am using an HTTP proxy. Any help ?

The IP needs to be within one of the subnetworks of the VLANs on the interface of your gateway that is provided with a connection; if you don't know what this is and don't want DHCP, you should contact your network administrator or attempt to figure this out further.

Well the IP range which I wanna access is 172.31.108.. I have been allotted 172.31.80.. Both IPs have been allocated different proxies for internet connection. My proxy becomes extremely slow at night whereas that of the aforementioned is reasonably fast.

Sounds like a dorm situation. Well, if you try to set a 172.31.108.x IP but your gateway is configured for 172.31.80.x it simply won't work because it is not configured to do something with source traffic from 172.31.108.x. In more technical terms, this means that 172.31.108.x is not in the subnetwork mask of the 172.31.80.x interface and/or there is no correct routing table entry.
Being able to connect TO 172.31.108.x does not mean you can connect FROM 172.31.108.x. This is the exact same idea that you and I can visit Super User just fine but we cannot be in the LAN of Super User unless we physically connect (or VPN) ourselves to the gateway in the server room of Stack Exchange OR if the network administrator explicitly sets up the required magic to do it remotely.
TL;DR: Tell your network admin that it is slow, exercising his responsibility to fix it. If the machines and links are similar; someone on the network might be hogging it, or a machine or link is defective.

redpajama_set_name: RedPajamaStackExchange


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Home Radio News Industry Learns Of Ramar Founder's Death
Industry Learns Of Ramar Founder's Death
The late Ray Moran
LUBBOCK, TEX. — A man considered by many to be "a pioneer broadcaster" has died.
Ray Moran, founder of Lubbock-based radio and TV station owner Ramar Communications, was 82. His death was on Feb. 11, KJTV-34 reports; industry trade publications became aware of the news on Tuesday (2/20).
Moran's early career achievements include stints as GM of radio stations KRST & KRZY in Albuquerque. In 1972, he founded former Lubbock radio station KTEZ.
His career in radio led to TV station ownership, as KJTV was launched as an unaffiliated TV station in 1981. It became a charter FOX affiliate in 1986, and in 2000 launched its own news division.
Today, Ramar — a combination of the names Ray and wife Mary Moran, who survives him — owns 16 radio and TV stations across Texas, New Mexico and Colorado.
Moran was a member of the Texas Association of Broadcasters, and served as President of the New Mexico Broadcasters Association and the Albuquerque Little Theater.
Moran was a longtime supporter of Texas Tech University's College of Media and Communications. He was inducted into the TTU COMC Hall of Fame in 1993. He chaired the COMC Foundation Committee from 1987 to 1992, and served on the Mass Communications Advisory Council. He received the Silver Medal Award of the American Advertising Federation, Lubbock Chapter, in 1983.
Funeral services were held Feb. 15.
In lieu of flowers, please direct any gifts in Ray's honor and memory to All Saints Episcopal School of Lubbock at 806-745-7701, in care of Celeste Thompson; or the Texas Tech College of Media and Communication.
Ramar Communications
Ray Moran
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RBR+TVBR has been reporting on the business of broadcasting for nearly three decades. Beholden to no one, it is independently owned.


text:
All Trips and tours
Travel to all the properties
with a BritRail Spirit of Scotland Pass
With thousands of years of history, Scotland has plenty to offer those who like to explore. The Historic Scotland Explorer Pass gives holders free access to Scotland's most famous, most spectacular and most intriguing sites, and is great value for money whether you're on a short break or a longer tour of Scotland.
Access to 77 sites across Scotland
Comes with information pack including brochures, a guidebook and location map
Includes access to Edinburgh Castle, Stirling Castle, Urquhart Castle at Loch Ness, Melrose Abbey and Skara Brae
Pass provided by the Scottish government's official heritage organisation
All under 16s must be accompanied by an adult
Visitors that require the assistance of a carer are asked to pay admission according to their age category. One carer can accompany a disabled visitor for free.
Buy with confidence – we are the official shop of the British Tourist Authority, VisitBritain
Flexibility – use your pass to visit up to 77 sites across Scotland freely during your pass validity
This product is sold by VisitBritain and is provided by our supplier, Historic Environment Scotland.
The Historic Scotland Explorer Pass is a great value way of discovering Scotland's history and heritage. Historic Scotland is the official organisation responsible for many of the country's castles, palaces, abbeys and prehistoric sites, so you can buy an Explorer Pass confident that it includes the very best that Scotland has to offer.
The sites included in the pass are listed in the 'Property list' tab
Collecting your Explorer Pass couldn't be simpler.
When you purchase this product, you will receive an e-voucher by email
Print this voucher and take it to one of the redemption properties where it will be exchanged for a pass
Please note that we do not sell disabled tickets. Any visitors that wish to buy a disabled ticket need to buy the appropriate non disabled ticket and up to one carer will be admitted free.
In order to ensure a safe and secure visitor experience at all times, random bag checks are in operation at Stirling Castle and Edinburgh Castle. Please also note that suitcases and large rucksacks over 30L will not be permitted and there are no storage facilities available for large items, including pushchairs. This may result in longer waiting times for entry to both of the Castles.
Some sites close in winter so please be sure to check before you travel
All sites are closed on 25th and 26th December
Visits to Maeshowe are by guided tour only. Tours will depart from the new Maeshowe Visitor Centre (at Stenness). You are strongly recommended to reserve your place on the tour and avoid disappointment. Booking details will be on your e-voucher
Please note, from the 11 June, the east area of St Andrews Cathedral will be inaccessible until further notice
The Historic Scotland Explorer Pass can be redeemed from any of the following locations.
St Andrews Cathedral (Please note, from the 11 June, the east area of St Andrews Cathedral will be inaccessible until further notice)
Adult (16+)$45.50
Child (5-15)$27.50Under 5s free
Concession$36.5060+ and students with valid ID
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Which Heritage Pass
Whether it's castles, beautiful gardens or stately homes you're after, there's a pass for you
From the lavishly-decorated State Apartments to Mary, Queen of Scots' Chambers, discover the regal splendour of Her Majesty The Queen's official residence in Scotland.
Loch Ness and Scottish Highlands Tour - 1 day (Highland Explorer)
A guided day tour to Loch Ness taking in the Scottish Highlands' 'must see' sights
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Taste whisky at an award-winning distillery and explore the beautiful Scottish countryside
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text:
Five Us Soldiers Were Wounded In Iraq
*Five US soldiers were wounded in Iraq Monday, along with an Iraqi translator, according to AFP. In one attack, guerrillas gutsily fired an anti-tank rocket near Baghdad police headquarters, wounding 3. The other attack took place on the dangerous road to the airport. On Sunday, a US soldier and two Iraqis were killed by a grenade attack on a US convoy near Baquba, a US military spokesman announced Monday.
*In Khalidiya, a riot broke out. First, guerrillas launched a rocket-propelled grendade at a US military vehicle that was accompanied by newly trained Iraqi police. The police fired back. This action appears to have enraged the Khalidiya townspeople, who mobbed the town hall and police station, setting fire to them. The US military then called for helicopters to disperse the crowds and restore order. Khalidiya is in the Baathist/ Sunni Islamist triangle. ( – AFP) The Iraqi people just seem still unwilling to dance in the streets for joy at the American presence, the way the Wall Street Journal promised us they would. At least CNN covered the Khalidiya uprising. A lot of this sort of thing doesn't even get mentioned on US television news.
*There have been seven attempts on the lives of former Baathist officers in Baghdad in the past week, with 3 killed and 7 wounded. It is not known who is behind a wave of reprisal killings against the technocrats and high officers of the former regime. -al-Zaman.
*Iran's deputy minister for foreign affairs, Husayn Sadiqi, came to Baghdad on the first formal visit of his ministry after the fall of Saddam, meeting with Interim Governing Council president Ibrahim Jaafari. Ali Reza Haqiqiyan, Iranian ambassador in Baghdad, was also present. Jaafari said that Saddam had not only harmed Iran (in the Iran-Iraq war) but had also inflicted great harm on Iraq itself. He said, "We thank God, who has saved us from that regime." (-AFP) (This is a clever way for an Iraqi Shiite to deflect criticism for cooperating with the US; he simply blamed the war and its aftermath on God, and who can argue with cooperating with God's will?) The delegation had met Saturday with IGC members Massoud Barzani and Abdul Aziz al-Hakim (deputy head of the Supreme Council for Islamic Revolution in Iraq). Al-Hakim discussed with the Iranian officials the future of bilateral relations between Iran and Iraq. Tehran had hosted SCIRI since its founding in 1982 and has close relations to it. But SCIRI and other theocratic Shiite groups are not willing simply to subordinate themselves to Iranian Supreme Jurisprudent Ali Khamenei. The ideas of Iraqi nationalism and popular sovereignty have permeated even the religious Shiites of Iraq. The US is worried half to death that the Iranians will gain influence in post-Saddam Iraq. Of course they will. They are nearby, and have lots of historical ties with Iraqi Shiites. But that isn't the same as Iranian dominance, which Iraqis won't accept.
*Hannah Allam of Knight-Ridder has an interesting article on the Shiites and the US. But she just gets some things wrong. Grand Ayatollah Ali Sistani has not called for a "strict separation of religion and state." On the contrary, he has called for an Islamic state with shariah or Islamic law as its basis. What he has opposed is clerics getting involved in day-to-day politics. That is different from wanting a separation of religion and state. Then, Muhammad Baqir al-Hakim of the Supreme Council for Islamic Revolution in Iraq has not called for a secular government. He also wants an Islamic republic. It is just that he recognizes that initially the Iraqi government will be a pluralistic parliamentary system. In the long term, he is sure Iraqis will opt for Iranian-style theocracy, with him as the Supreme Jurisprudent. These are subtle distinctions, but they have to be maintained if we are to understand Shiite politics in contemporary Iraq. See http://www.bayarea.com/mld/mercurynews/news/special_packages/iraq/6456779.htm
*Firms that are more than 10% government owned have been excluded by Paul Bremer for competing for telecom licensing in Iraq. This rule is being vigorously protested by Bahrain's Batelco (40% government owned). It also excludes most companies in Western Europe. Batelco moved into the Iraq market, where the Americans have still not restored the telephone system, a couple of weeks ago, but was shut down by the Americans for not having a license. Meanwhile, the Bremer administration had awarded Worldcom rights in Iraq, even though a) it had no expertise or experience in wireless telephony and b) it should have been excluded from government contracts insofar as it has been guilty of massive fraud and cheating. Most of the world has not privatized things like telephone companies, and to make a rule like this is a sneaky way of preserving the Iraq market for American firms, including ones with shady business practices. Mr. Bremer comes to this job with a good reputation. My advice to him is to avoid even the appearance of impropriety, because the American experiment in Iraq can easily be discredited by invidious rules that look like favoritism. See: http://www.gulf-daily-news.com/Articles.asp?Article=58007&Sn=BNEW. One solution: Give the Iraqi Interim Government Council a say in this matter. Do they want to exclude Batelco? If not, then the US shouldn't, either.


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Chad Evans with his team Momma and Smoke uses a walking plow to show how it was done in the early 1900's, at the Malcolm Blue Farm in Aberdeen. Ted Fitzgerald/The Pilot
Hello NC Initiative Celebrates Rural North Carolina
From hearing the calls of endangered birds in a sanctuary in eastern North Carolina to seeing a mountain sunrise in the west, our state has unlimited rural treasures awaiting discovery.
We are a rural state, with 80 of 100 counties beyond the hustle and bustle of major cities. Without a doubt, the state's most beautiful natural resources can be found in rural North Carolina.
In 2020, the N.C. Department of Natural and Cultural Resources is launching a new initiative to celebrate North Carolina's rural counties.
Hello NC will explore rural culture across the state, focusing on hometown heroes and histories, highlighting rural heritage, foods, crafts, festivals and traditions. Hello NC is a platform for rural communities to tell their stories in their voices. These stories will be told through rich photography and video that represents the unique natural beauty and cherished culture from each community.
"North Carolina's rural population is larger than that of any other state, except Texas," said Susi Hamilton, secretary of the N.C. Department of Natural and Cultural Resources. "With Hello NC, we want to highlight and uplift our rural communities, provide resources for education and outreach, and explore grant funding opportunities to help these counties thrive."
N.C. Department of Natural and Cultural Resources staff will engage with local partners in seeking local programming and events for sponsorship opportunities. These events will be supplemented with DNCR traveling exhibits and educational resources to highlight the state's extraordinary rural vibrancy and cultural diversity. In addition, historical information from the State Archives will be collected and shared with local communities.
Hello NC initially will focus on four counties: Halifax, Madison, Columbus and Ashe. Our goal is to share and promote authentic and compelling stories about North Carolina's rural counties starting with this mix from the eastern and western parts of the state.
All N.C. rural communities can connect with Hello NC through our online Partner Resources and Toolkit.
To learn more, visit www.hello-nc.com.
Please purchase a subscription to continue reading. Subscribe today and support local community journalism.
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Sun., Jan. 17, 2021


March is almost towards the end and it has been a busy quarter for all of us here at CryptoBLK, with continuing efforts for onboarding support to our InsurTech solution MIDAS and our ever-ongoing development of enterprise consortium Blockchain applications including Voltron, Atlas, and more. In this month, our management team joined an interview from the leading publication Automobile and Blockchain Asset Review, as well as joined in several community meetups to share CryptoBLK's company vision and DLT innovations.
Since the launch of MIDAS, we have continued with the onboarding of insurance companies and furthered our support to the integration works carried out with our collaborators. This month, our CTO Andrew Hon, together with the Chairman of Hong Kong Federation of Insurers' (HKFI) Accident Insurance Association, Philip Kwan, were interviewed by Automobile (《車主》雜誌) about the MIDAS innovation which applies cryptographic hash-based message authentication code technology to data records which have the minimum amount of information required for authenticating a motor insurance document without storing Personal Identifiable Information on the DLT system.
Our CEO Dr. Duncan Wong introduced consortium Blockchain trade finance applications and DLT solutions during the panel of FinTech Use Cases in Industries at Deloitte Hong Kong office in the Blockchain Applications in Business World event jointly organized by AICPA, CIMA and Deloitte on March 8.
Our CEO Dr. Duncan Wong shares his view on the mainstream adoption of enterprise Blockchain and the latest development of several DLT projects that our CryptoBLKers are working on including InsurTech MIDAS, trade finance solution ATLAS and property asset value management platform TOPAZ during the interview of Blockchain Asset Review, check out more here.
CryptoBLK is thrilled to have the chance to introduce our company's vision and mission to HSBC's global team during their visit to HKSTP (Hong Kong Science and Technology Park). Our team presented not only the DLT ecosystem and landscape, but the latest DLT innovations offered by CryptoBLK including trade finance solutions Voltron and ATLAS, the documentation authentication solution MIDAS, and the asset valuation and management solution TOPAZ. The team has received positive feedback from HSBC's delegates, and are currently exploring further adoption opportunities of DLT in the banking industry.
Our CBO Lei Xiao presented CryptoBLK's philosophy during a meetup with the technopreneurs from the companies at HKSTP during InnoXchange on March 27. In the interactive exchange, Ms Xiao introduced real-world DLT adoption for business and shared some case studies based on our works in the Blockchain in trade finance and document authentication and its production prerequisites session. The workshop facilitated the exchange of new ideas and insights into new areas, opening opportunities for CryptoBLK and other potential collaborators.
CryptoBLK co-hosted a FinTech showcase together with HKSTP for Thailand's leading commercial bank, Kasikornbank's (KBank) delegates, showcasing the company's latest DLT R&D solutions and technologies including the trade finance consortium platform ATLAS, the property valuation solution TOPAZ, the motor insurance documents authentication platform MIDAS and the cryptocurrency platform Abelian. KBank delegates commended Hong Kong's technology ecosystem and the enormous potential market connecting to Mainland China, as well as CryptoBLK's DLT innovations.
Our CEO Dr. Duncan Wong spoke on a lecture on security technologies and introduced Blockchain technology and its use cases to students at the City University of Hong Kong. The students were very enthusiastic to the technologies and showed great interest in the applications of Blockchain to the real world.


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Q: Dismiss / Present Modal View Controller - again viewdidLoad is calling I have faced one strange problem, when I click on the below button informationBtn_clicked. InformationView is coming.
MainView
-(IBAction)informationBtn_clicked:(id)sender{
       InformationView  *obj_Info=[[InformationView alloc] initWithNibName:@"InformationView" bundle:nil];
       UINavigationController *navigationObj = [[UINavigationController alloc] initWithRootViewController:obj_Info];
       [self.navigationController presentModalViewController:navigationObj animated:YES];
}

NextView
After below back btn clicked dismis the view controller;
-(void)btnBackClicked:(id)sender{
    [self dismissModalViewControllerAnimated:YES];
}

Here, my problem is when I dismiss the NextView, again calling main view the viewDidLoad method. My project is running in iOS 5, I am using ARC.
I am checking one way that is the Release the obj_Info but after result the same plz Help Me my English is very poor try to understand me.

A: The problem is that in the line:
UINavigationController *navigationObj = [[UINavigationController alloc] initWithRootViewController:obj_Info];

you initialize the navigation controller with obj_Info as a root view controller. So when you dismiss the modal view controller, the navigation controller shows its root view controller, which happens to be the same as the modal view controller.
Try changing the line I mentioned with:
UINavigationController *navigationObj = [[UINavigationController alloc] init];

A: The link he gave you shows there may be a bug in Apple's code that is related to your problem.  For now, maybe just workaround (e.g. in viewDidLoad, set a boolean, and then clear it in viewDidUnload; if it's set when you enter viewDidLoad, just return)


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5 Train Stations with the Dashing European Classical Architecture in Latin America
Latin America's train stations are a product of the phenomenon of the Industrial Revolution. The Industrial Revolution brought various railways which controlled the Latin American region. Then it influenced the architectural style of train stations in Latin America. These buildings became the pinnacle of valuable history that had transformed the entire continent.
The existence of railways is very important in the process of great change that is taking place in South America. The economic success achieved by South America motivates students to continue their studies in Europe as well as an effort to strengthen their existence on a global scale. After completing their studies, they returned to Latin America, some of them were architects who were interested in designing beautiful buildings oriented to Classical European architectural designs.
This time Travel Addict will review 5 train stations with classic and historical style in Latin America This building not only describes the economic success that has been achieved, but also a representation of the strength and independence of the Latin American countries. This row of stations is a silent witness to a meaningful history that is immortalized in its architectural prowess.
Before further reading, this article, also read Travel Addict's review regarding tips for a vacation in the desert: 5 Tips for Vacation in the Desert that Make Your Touring Experience Unforgettable.
Mapocho Train Station – Santiago, Chile
Luz Train Station – São Paulo, Brazil
Constitución Train Station – Buenos Aires, Argentina
Júlio Prestes Train Station – São Paulo, Brazil
Desamparados Train Station – Lima, Peru
The Estacion Mapocho train station is adjacent to the Mapocho river, viz the river that divides the capital of Chile, Santiago, in two. The name of this place first came from a native of Chile who named it Mapu Chuco, which means "water that penetrates the island". The construction project of Estacion Mapocho was led by an architect named Emilio Jéquier, together with the construction of the Santa Lucia Hill park and the Chilean National Museum of Fine Arts. The project also aims to celebrate Chile's century of independence in 1910.
Mapocho Train Station-Santiago, Chile. Image source: Santiago Chile
The architecture of the Estacion Mapocho train station building can be a strong testament to another beautiful architectural design that also resides in Santiago. More interestingly, the exterior design of the Mapocho building reminds many people of the ancient European building architecture. If you are interested in visiting, Mapocho can be visited bypassing the Cal y Canto metro station. In addition, the location is close to other tourist destinations, such as La Vega and Mercado Central.
Apart from being able to enjoy a special building structure, now the Estacion Mapocho train station is always busy with various events that are no less interesting. If you are lucky, you can enjoy music concerts, art exhibitions, and conventions. Even though the music concert is considered even though it always presents traditional Chilean music, many people regret the poor quality of the sound produced. This is natural because the building itself is specifically designed to reduce sound, not improve the sound.
The Estação da Luz train station is an important landmark from São Paulo which is precisely in the Luz area with a building area of more than 7,500 square meters. This building was originally designed by Baron de Maua in 1867. However, it was rebuilt by British architect Charles Henry Driver from 1895 to 1900. The new building design is built in the Victorian style, namely the neo-classical architectural style, where the exterior design resembles the buildings of Westminster Abbey and Big Ben in London, England.
Luz Train Station – São Paulo, Brazil. Image source: WIKIMEDIA COMMENS
The reconstruction process of the Luz train station was carried out in a different country. Initially, the building was assembled in Glasgow, UK. Then it was disassembled again so that it could be easily shipped to São Paulo. The hope is that this building can function much more efficiently than the previous buildings that have been around for more than 100 years.
The Luz train station was completed in 1901 and has since been used as an entry port for Japanese and European immigrants, as well as an exit port for Brazilian coffee exports. Today the building houses the Museu da Língua Portuguesa, an interactive museum that explores the languages that have influenced Brazilian Portuguese. Apart from that the museum also offers training, public lectures, consultations for linguists and language teachers.
The most interesting part of this one train station is definitely the towering clock tower, marking this building as one of the tallest landmarks in the city for quite some time. No wonder, because the Luz building was inspired by several train station buildings in the United Kingdom such as the Pancras train station in London.
The Constitución train station was built in 4 stages during 1800-1900. The architecture of this building is a mix of neo-classical and victorian architectural styles which has 14 train lines. In a matter of days, approximately 500,000 passengers visited.
Constitución Train Station – Buenos Aires, Argentina. Image Source: WIKIMEDIA COMMENS
The Constitución train station is 2 km south of the landmark Constitución area, Constitution Square. The architectural style of this building is a tribute to various periods. The French style of the façade first appeared in 1883 in the baroque architectural style of the castle buildings in Maisson Laffitte, France. Then in 1923-1925, a magnificent main hall was built using materials sent from Liverpool, England.
Júlio Prestes Train Station – São Paulo, Brazil. Image Source: WIKIMEDIA COMMONS
The Júlio Prestes train station is a historical landmark located in the center of the Luz area. Júlio Prestes is also a historical tourist destination. The original building of Júlio Prestes station was completed in 1875 which was later used as a coffee exchange. Increasingly intense coffee exchange activities forced the Sao Paulo government to build a railway that was named Sorocabana.
In 1925, the Júlio Prestes building was renovated by an architect named Cristiano Stockler. The architectural style of the new building takes its inspiration from the Grand Central Station building in New York. The renovation process took 12 years which ended in 1938. The new building is 26 meters high with a total building area of 25,000 square meters.
Júlio Prestes is popular for its 1,000-square-meter concert hall. The concert hall is named Sala São Paulo. Sala São Paulo is now the venue for several orchestral groups to perform. Uniquely, this concert hall has a movable ceiling, so that the acoustic sound quality produced in the room can be optimized at will.
Desamparados is a train station located in Lima, Peru. In the 20th century, Desamparados station was one of the world's greatest train journeys. The name Desamparados is taken from the name of a church called Nuestra Señora de los Desamparados. Desamparados development was started in 1890 by the Peruvian Corporation. Then 3 years later, the Lima-La Oroya route officially opened, now better known as the Ferrocarril Central Andino.
Desamparados Train Station – Lima, Peru. Image Source: WIKIMEDIA COMMONS
Desamparados architecture was designed by Peruvian architect Rafael Marquina. Desamparados is the first building in Peru to apply the steel frame technique in the construction process. The building design combines the typical details found in buildings in Paris, such as the Art Nouveau architectural style found on the skylights, the poles decorated in a neo-classical style, and building materials made of iron.
In 2009, the train station was renamed "Casa de la Literatura Peruana" (House of Peruvian Literature). Today Desamparados is home to literary books written by Peruvian authors. In addition, this place is also home to a Cultural Center, a children's reading room, art exhibitions, and a library.
America railway station train Traveling
Sucia Ramadianti


text:
Greenways North Field Habitat Restoration
Glossy buckthorn has spread and dominates the central and eastern portions of the field. Photo by Chuck Walla
Cardboard was placed over a plot of land to prepare the site for planting of native wildflowers.
Contractors and volunteers work to improve wildlife habitat at Greenways in Wayland. Photo by Chuck Walla
After the cardboard was removed, the plot was readied for planting.
Volunteers helped to plant 1800 plugs into the plot.
Fencing was installed to help ensure the natives would have a strong start.
SVT volunteers getting ready to water wildflowers
Restoration plot after 6 weeks of growth
Restoration plot in bloom after 12 weeks of growth
Look what's happening at Greenways! Gone are the shrubs and in a field that just a few years ago was dominated by invasive plants such as Glossy buckthorn, Multiflora rose, and Purple loosestrife, an open field habitat has emerged. Due to diligent management practices, SVT has been able to see a marked decline in the presence of these aggressive invasive species.
Now, with invasive control efforts winding down, SVT is able to start planting for the future! With a suite of native grasses and wildflowers being planted this summer, the North Field at the Greenways Conservation Area begins the next step of its restoration back into a habitat where a diversity of butterflies and other pollinators will soon find a new home.
In 1995, our regional botanist, Frances Clark, described the north field as being "rich in both upland and wet meadow plant species." She went on to say that "the field has the greatest diversity of butterflies of any other habitat at the Greenways Conservation Area. The numbers and coverage of invasive exotic species is low at this time."
Sadly, over the last 17 years, the quality of the field has dramatically declined. The native flora diversity has declined precipitously, as has the number and diversity of butterflies. Glossy buckthorn has spread and dominates the central and eastern portions of the field. Multiflora rose is also common in the field. Native plant diversity has declined with sensitive fern being dominant.
SVT initiated limited habitat restoration from 2005 to 2007. With a grant from the Massachusetts Landowner Incentives Program, we hired a contractor to clear the field perimeters of invasive shrubs. However, the glossy buckthorn in the field interior remained a problem that would require use of herbicides to effectively control.
In 2012 as part of a CISMA project, SVT received a grant from the National Fish & Wildlife Foundation's Pulling Together Initiative.
SVT hired the New England Wild Flower Society to conduct selective herbiciding of plants in the field. Volunteers are also assisting with this effort. It will require several years of treatment to yield the ultimate goal of reducing the invasive plant cover by over 75% and increasing the native plant and butterfly diversity.


The celebration of Pride has exploded all over the world in more recent history, and with that comes a whole host of colourful celebrations. I always associate Pride with sunny weather, and seeing as it's been raining here for the last few days (I think summer has definitely decided to show its face somewhere else at this point) I decided to have a look back through some of my more sun-soaked images from the past few months, plenty of which were taken at Pride. And so, for those of you currently experiencing a winteresque summer day, I thought I could put together a little photo journal to brighten things up a bit.
On 4th August, Pride came to Brighton and I headed down to the parade armed with my camera to try to capture everything that was going on. It became obvious pretty fast where the parade would be coming through as people started lining the streets well in advance.


Sophie Whittle of Gonzaga has been making history for her school for months now and can add another notable accomplishment, as she takes over the No. 1 position in the ITA Division I women's singles rankings released today. Whittle, who won the ITA/Riviera All-American title in October, takes over from Katarina Jokic of Georgia, who lost to Ana Roman of South Florida in the Bulldogs first match of the Kick-off Weekend. These are the first individual rankings since last November.
NCAA singles champion Petros Chrysochos of Wake Forest stays at No. 1 on the men's side, while the NCAA champion Wake Forest men also remain at the top of the rankings. There are no women's team rankings this week, with the Women's National Team Indoor Championships beginning Friday in Seattle. The draws are out for the event, with Stanford, the NCAA champion, the top seed, followed by defending champion North Carolina, Duke and Vanderbilt. The ITA preview is here.
The top 10 in singles and top 5 in doubles are below. The full list can be found by clicking on the link in the headings.
The Tennis Channel/USTA poll does have both men's and women's team rankings this week. Below are the top 10, with the full lists available at usta.com. Previous week's ranking is in parentheses.


Despite some uncertainty around U.S. government policy and the failure of drone maker Lily Robotics, robotics funding continued to grow in the first quarter of 2017, especially around self-driving cars and AI.
In the first quarter of 2017, robotics funding kept flowing to autonomous vehicles, artificial intelligence, and the chips that power them all. However, drone maker Lily Robotics' struggles and geopolitical uncertainty cast a shadow over the still-growing robotics industry.
Despite that economic uncertainty, the U.S. government is moving ahead with robotics funding. In January, the U.S. Department of Defense awarded $80 million to American Robotics, a nonprofit founded by Carnegie Mellon University.
Carnegie Mellon University is a major partner in the Advanced Robot Manufacturing Group.
That grant joins $173 million from other organizations for the Advanced Robot Manufacturing Group. It will support research toward improving automation in the aerospace, automotive, composites, electronics, logistics, and textiles industries.
The consortium will be based in Pittsburgh, but millions of dollars will be spread to other high-tech centers such as California and Massachusetts.
In the U.K., vacuum cleaner magnate Sir James Dyson invested $2.5 billion in R&D facilities for AI, robotics, energy storage, and vision systems at a former Royal Air Force Base.
Other than iRobot, there are few household names in robotics, but that could soon change, thanks to service robots such as SoftBank's humanoid Pepper.
Apple Inc. pledged $1 billion to SoftBank Group Corp.'s Vision Fund, which has the bold goal of helping SoftBank become "the world's No. 1 robotics company." Qualcomm, Foxconn, and Oracle have reportedly pledged $1 billion each, and Saudi Arabia has said it will contribute $45 billion.
In February, Lux Capital closed its fifth startup fund at $400 million. That fund has invested in startups in 3D printing and autonomous ground and marine vehicles.
Continuing a trend we observed last year, chipmakers continued to show interest in self-driving cars and artificial intelligence as the next big users of their technology.
For instance, chipmaker Intel Corp. spent $15.3 billion on Mobileye NV, a major supplier of machine-vision technology for driver-assist features.
Intel is also spent $100 million on the Responsive Retail Platform, which plans to apply Internet of Things capabilities to improve the shopper experience.
Also, Belgian-German chipmaker X-Fab Silicon Foundries SE announced an initial public offering of $350 million. Its chips are intended for sensors to assist smartphone users and motorists.
Rolls-Royce is working on autonomous ships.
Toyota Industries Corp. paid $260 million for systems integrator Bastian Solutions LLC and established its Toyota Advanced Logistics Solutions unit.
In another internal development, Siemens plans to spend $22 million building a workforce training program for Industry 4.0.
Elsewhere in robotics funding, Rolls-Royce Holdings PLC got $243 million from Tekes, the Finnish Funding Agency, for research into autonomous marine vessels.
How Well Did Our 2016 Robots and Markets Predictions Do?
Chinese companies continued offering robotics funding for capabilities to balance its manufacturing market.
Midea Group Co., which last year bought Germany-based KUKA Group AG, added to its portfolio. It acquired Israel-based Servotronix Motion Control Ltd. for $170 million.
In addition, Chinese AI startup CloudMinds Inc. raised $100 million in its Series A round. Investors included SoftBank, and CloudMinds wants to build the cloud-based "brains" for robots.
Not to be left behind, Ford Motor Co. paid $1 billion for Argo AI. Pittsburgh-based Argo AI is developing systems for Ford and for licensing to other self-driving cars.
For more analysis of Q1 of 2017, download our transactions report.


text:
Transcripts of unknown function (TUFs) is the name that has been suggested for known RNA transcripts of DNA whose function is unclear.  Most TUFs are probably ncRNAs, such as RNAi or snoRNAs, but could also represent a whole new class of ncRNA. The DNA sequences for TUFs reside in the intergenic or intronic regions of the genome, which is often called junk DNA.  This currently makes up much of the human genome, although the percentage of the genome that falls under the TUFs category is likely to go down significantly as more progress is made towards understanding the many roles of RNA.

Categories of TUFs
Broadly speaking, TUFs can be classified into three categories:
 TUFs that are complementary to sense transcripts of protein-coding genes
 TUFs that are novel isoform transcripts of protein-coding genes; this can include expressed pseudogenes
 TUFs that reside on the same strand as protein-coding genes in the intronic region or entirely in the intergenic region

Other information
There are very few details known about TUFs, which is why the phrase even exists, but one thing that has been shown several times is that they are not very conserved between mice and humans.  This could be due to a number of factors, including more recent evolution in the primate lineage or extensive post-transcriptional modification of the RNA.

References

Molecular genetics
RNA
Non-coding RNA

redpajama_set_name: RedPajamaWikipedia


text:
Gulf and Middle East
Kerala-based software company wins Grand Challenge for developing video conference solution
NetIndian News Network
Published on : 23 Aug, 2020 , 3:58 am
New Delhi, August 23, 2020
Kerala-based Techgentsia Software Technologies Private Limited has won the Grand Challenge for Developing Video Conference Solution, Minister for Electronics & IT, Communications Ravi Shankar Prasad said last week.
Announcing the results of the Grand Challenge on Thursday, Prasad said he was glad that Indian entrepreneurs and innovators have responded to the call for Aatma Nirbhar Bharat (self-reliant India) given by Prime Minister Narendra Modi. They have come up with some world-class video conferencing solutions in a short span of four months, he said.
"We are committed to developing India's software product and the mobile app economy in a big way and efforts like this will go a long way in that direction," he added.
The Ministry of Electronics & Information Technology had announced an Innovation Challenge for Development of a Video Conferencing Solution under the Digital India Initiative on April 12. The Innovation Challenge was open for participation from industry, start-ups and individual experts.
An overwhelming response was received from across the country, with a total of 1983 applications being received, which were evaluated and subsequently supported through a three-stage process (Ideation, Prototype and Product Stage), an official press release said.
Out of these, 12 applicants with innovative VC solutions were shortlisted to develop/ mature the prototype for which support of Rs 10 lakh each was provided. The prototypes thus evolved were further evaluated by a jury comprising senior officers of the Government, reputed academicians and eminent members from the IT industry to shortlist five applicants for building a ready-to-market product.
The five shortlisted applicants were further provided financial support of Rs 20 lakh (for three) and Rs 15 lakh (for two), mentorship, testing and onboarding onto NIC cloud. Jury and Mentors comprising eminent experts from Industry, Academia and Government provided extensive support to the Challenge on pro bono basis. The five finalists have pitched the solution and jury which evaluated each of these products in detail and declared the winners.
The jury declared Vconsol, a product of Alappuzha (Kerala)-based Techgentsia Software Technologies Private Limited, as the winner. The winner of the challenge will be provided financial support of Rs. 1 crore with additional Rs. 10 lakh towards O&M for the next three years and will be adopted for use by Government through a contract.
The Jury also selected the products developed by three applicants as potential products and decided to offer a developmental contract to be supported by Rs. 25 lakh each for further maturing their product within three months.
These three products are Sarv Webs Pvt. Ltd. (Sarv Wave), Jaipur; People Link Unified Communications Pvt Ltd (Insta VC), Hyderabad; and Instrive Softlabs Pvt Ltd (HydraMeet), Chennai.
These three products will be further analyzed by a technical committee and subsequently, Ministry of Electronics and IT will recommend to onboard all selected four products on Government e-Marketplace (GeM).
All the video conferencing products will also be provided support of STQC, CERT-In, CDAC and NIC. It has also been recommended that all four products will be hosted on NIC cloud and NIC will facilitate for the adoption of these products for Government use through GeM. All teams including winning team shall also be free to market the product globally.
This entire process of Grand Challenge was conducted with active participation from some of the best experts working as mentors and members of the jury. The Ministry of Electronics and IT acknowledged the role played by NASSCOM president Debjani Ghosh, Chairman Indian Angel Network, Saurabh Srivastava, Sharad Sharma of iSpirit, Dr Rajat Moona from IIT Bhilai, Professor Santanu Chaudhary from IIT Jodhpur, and Professor Yatindra Nath Singh from IIT Kanpur, along with senior officers of the Ministry.
VideoConferenceSolution
GrandChallenge
SoftwareCompany
Techgentsia
VConsol
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text:
package shef.nlp.supple.prolog.cafe;
import jp.ac.kobe_u.cs.prolog.lang.*;
import jp.ac.kobe_u.cs.prolog.builtin.*;

/*
 * *** Please do not edit ! ***
 * @(#) PRED_cvsid_compile_grammar_1.java
 * @procedure cvsid_compile_grammar/1 in compile_grammar.pl
 */

/*
 * @version Prolog Cafe 0.8 November 2003
 * @author Mutsunori Banbara (banbara@kobe-u.ac.jp)
 * @author Naoyuki Tamura    (tamura@kobe-u.ac.jp)
 */

public class PRED_cvsid_compile_grammar_1 extends Predicate {
    static IntegerTerm s1 = new IntegerTerm(36);
    static IntegerTerm s2 = new IntegerTerm(73);
    static IntegerTerm s3 = new IntegerTerm(100);
    static IntegerTerm s4 = new IntegerTerm(58);
    static IntegerTerm s5 = new IntegerTerm(32);
    static IntegerTerm s6 = new IntegerTerm(99);
    static IntegerTerm s7 = new IntegerTerm(111);
    static IntegerTerm s8 = new IntegerTerm(109);
    static IntegerTerm s9 = new IntegerTerm(112);
    static IntegerTerm s10 = new IntegerTerm(105);
    static IntegerTerm s11 = new IntegerTerm(108);
    static IntegerTerm s12 = new IntegerTerm(101);
    static IntegerTerm s13 = new IntegerTerm(95);
    static IntegerTerm s14 = new IntegerTerm(103);
    static IntegerTerm s15 = new IntegerTerm(114);
    static IntegerTerm s16 = new IntegerTerm(97);
    static IntegerTerm s17 = new IntegerTerm(46);
    static IntegerTerm s18 = new IntegerTerm(55);
    static IntegerTerm s19 = new IntegerTerm(48);
    static IntegerTerm s20 = new IntegerTerm(56);
    static IntegerTerm s21 = new IntegerTerm(53);
    static IntegerTerm s22 = new IntegerTerm(50);
    static IntegerTerm s23 = new IntegerTerm(45);
    static IntegerTerm s24 = new IntegerTerm(49);
    static IntegerTerm s25 = new IntegerTerm(54);
    static IntegerTerm s26 = new IntegerTerm(51);
    static IntegerTerm s27 = new IntegerTerm(90);
    static IntegerTerm s28 = new IntegerTerm(110);
    static IntegerTerm s29 = new IntegerTerm(98);
    static IntegerTerm s30 = new IntegerTerm(116);
    static IntegerTerm s31 = new IntegerTerm(115);
    static SymbolTerm s32 = SymbolTerm.makeSymbol("[]");
    static ListTerm s33 = new ListTerm(s1, s32);
    static ListTerm s34 = new ListTerm(s5, s33);
    static ListTerm s35 = new ListTerm(s31, s34);
    static ListTerm s36 = new ListTerm(s30, s35);
    static ListTerm s37 = new ListTerm(s15, s36);
    static ListTerm s38 = new ListTerm(s12, s37);
    static ListTerm s39 = new ListTerm(s29, s38);
    static ListTerm s40 = new ListTerm(s7, s39);
    static ListTerm s41 = new ListTerm(s15, s40);
    static ListTerm s42 = new ListTerm(s13, s41);
    static ListTerm s43 = new ListTerm(s28, s42);
    static ListTerm s44 = new ListTerm(s16, s43);
    static ListTerm s45 = new ListTerm(s10, s44);
    static ListTerm s46 = new ListTerm(s5, s45);
    static ListTerm s47 = new ListTerm(s27, s46);
    static ListTerm s48 = new ListTerm(s26, s47);
    static ListTerm s49 = new ListTerm(s19, s48);
    static ListTerm s50 = new ListTerm(s4, s49);
    static ListTerm s51 = new ListTerm(s22, s50);
    static ListTerm s52 = new ListTerm(s26, s51);
    static ListTerm s53 = new ListTerm(s4, s52);
    static ListTerm s54 = new ListTerm(s25, s53);
    static ListTerm s55 = new ListTerm(s24, s54);
    static ListTerm s56 = new ListTerm(s5, s55);
    static ListTerm s57 = new ListTerm(s21, s56);
    static ListTerm s58 = new ListTerm(s19, s57);
    static ListTerm s59 = new ListTerm(s23, s58);
    static ListTerm s60 = new ListTerm(s22, s59);
    static ListTerm s61 = new ListTerm(s24, s60);
    static ListTerm s62 = new ListTerm(s23, s61);
    static ListTerm s63 = new ListTerm(s21, s62);
    static ListTerm s64 = new ListTerm(s19, s63);
    static ListTerm s65 = new ListTerm(s19, s64);
    static ListTerm s66 = new ListTerm(s22, s65);
    static ListTerm s67 = new ListTerm(s5, s66);
    static ListTerm s68 = new ListTerm(s21, s67);
    static ListTerm s69 = new ListTerm(s20, s68);
    static ListTerm s70 = new ListTerm(s19, s69);
    static ListTerm s71 = new ListTerm(s18, s70);
    static ListTerm s72 = new ListTerm(s5, s71);
    static ListTerm s73 = new ListTerm(s11, s72);
    static ListTerm s74 = new ListTerm(s9, s73);
    static ListTerm s75 = new ListTerm(s17, s74);
    static ListTerm s76 = new ListTerm(s15, s75);
    static ListTerm s77 = new ListTerm(s16, s76);
    static ListTerm s78 = new ListTerm(s8, s77);
    static ListTerm s79 = new ListTerm(s8, s78);
    static ListTerm s80 = new ListTerm(s16, s79);
    static ListTerm s81 = new ListTerm(s15, s80);
    static ListTerm s82 = new ListTerm(s14, s81);
    static ListTerm s83 = new ListTerm(s13, s82);
    static ListTerm s84 = new ListTerm(s12, s83);
    static ListTerm s85 = new ListTerm(s11, s84);
    static ListTerm s86 = new ListTerm(s10, s85);
    static ListTerm s87 = new ListTerm(s9, s86);
    static ListTerm s88 = new ListTerm(s8, s87);
    static ListTerm s89 = new ListTerm(s7, s88);
    static ListTerm s90 = new ListTerm(s6, s89);
    static ListTerm s91 = new ListTerm(s5, s90);
    static ListTerm s92 = new ListTerm(s4, s91);
    static ListTerm s93 = new ListTerm(s3, s92);
    static ListTerm s94 = new ListTerm(s2, s93);
    static ListTerm s95 = new ListTerm(s1, s94);

    public Term arg1;

    public PRED_cvsid_compile_grammar_1(Term a1, Predicate cont) {
        arg1 = a1;
        this.cont = cont;
    }

    public PRED_cvsid_compile_grammar_1(){}
    public void setArgument(Term[] args, Predicate cont) {
        arg1 = args[0];
        this.cont = cont;
    }

    public Predicate exec(Prolog engine) {
        engine.setB0();
        Term a1;
        a1 = arg1.dereference();

        if ( !s95.unify(a1, engine.trail) ) return engine.fail();
        return cont;
    }

    public int arity() { return 1; }

    public String toString() {
        return "cvsid_compile_grammar(" + arg1 + ")";
    }
}

redpajama_set_name: RedPajamaGithub


Welcome! Here you can find updates about school and class events. You may also like and follow my class facebook page-Mrs. Steele's Kindergarten.
** Sneakers are required for Phys. Ed.-our class participates Tuesday and Thursday.


Singapore, 1 September 2016 – CapitaLand Limited has unveiled its latest development Victoria Park Villas, a landed housing project located in Singapore's prime District 10. An exclusive and luxurious landed development in the vicinity of a Good Class Bungalow area, Victoria Park Villas offers 106 semi-detached houses and three distinctive bungalows that will feature contemporary designs and built-in sophisticated smart home systems. Occupying a 403,000 square feet site at the junction of Coronation Road and Victoria Park Road, the development is minutes away from Orchard Road, Holland Village and the Central Business District.
CapitaLand engaged critically acclaimed architect Mr Mok Wei Wei for the master planning of Victoria Park Villas estate, which takes on a modern, sleek architectural concept. One of the earliest recipients of the Designer of the Year Award at President's Design Award – Singapore's highest accolade for design excellence, Mr Mok worked on many award-winning projects such as the major refurbishments of The National Museum of Singapore and The Victoria Theatre and Concert Hall, as well as the design of residential developments including CapitaLand's The Nassim at Nassim Hill.
The floor area of the 106 semi-detached houses ranges from 4,166 sq ft to 6,943 sq ft, with prices ranging from S$4.4 million to S$7.6 million. Six of these houses come with a swimming pool on the ground floor. The three exclusive bungalows range from 10,904 sq ft to 11,539 sq ft in floor area and are priced from S$11 million to S$12 million. To allow homebuyers to move in readily, each house is tastefully adorned with premium fittings such as Italian-crafted Ernestomeda cabinetry in a fully-fitted kitchen with integrated appliances by Miele.
Designed for convenience and accessibility, each house comes with a private lift serving all levels, bedrooms with en suite bathrooms, as well as a covered car porch and bedroom at the basement on the road level. Homebuyers will be able to enjoy picturesque views of the lush, verdant surroundings from the roof terraces and bedrooms. With most bedrooms on the second floor, the spacious bedrooms at the basement and attic floors can also be converted into entertainment zones.
Victoria Park Villas is about a 10-minute walk from Farrer Road and Tan Kah Kee MRT stations, and surrounded by myriad dining, recreational and retail options at Holland Village, Dempsey Hill, ION Orchard, and Singapore Botanic Gardens. It is a 10-minute drive to Singapore's world-renowned Orchard Road shopping belt and the Central Business District.
It is also surrounded by reputable schools such as Nanyang Primary School, Raffles Girls Primary School, St Margaret's Secondary School, Hwa Chong Institution, Anglo-Chinese School International, National Junior College and the National University of Singapore Bukit Timah Campus.
Victoria Park Villas will be launched on Saturday, 3 September 2016. For viewing appointments of the showhouses at Victoria Park Grove, please call +65 9771 9898 or visit www.victoriaparkvillas.com.sg.


Chesapeake's stock selection style can best be described as flexible since most clients own both growth and value oriented companies that vary in terms of size. This allows portfolios to participate in all phases of the market cycle. Security selection is based on valuation relative to history and similar securities. The management process is disciplined and principled, using specific "buy" and "sell" price points.
The investment approach is opportunity driven. We research trends in the economic, social and political environment to develop investment themes that have "long legs". Investments in these themes have proven to be important to portfolio performance over time.
Chesapeake does not risk client funds by using short-term trading strategies. A firm may produce a remarkable quarter or even year, due to any number of one-time events. We look for companies with strong competitive positions that produce consistent superior results over time.
The foundation of income investing is the understanding of interest rate trends and the potential effect on investments.
We emphasize income stability, credit quality, and capital preservation. We purchase high-quality bonds and add income oriented, exchange-traded securities to enhance the total return for investors. Years of experience validate our choices.
Within the client's risk tolerance, we include preferred stock and convertible preferred stock in portfolios as warranted to increase the income stream and the opportunity for appreciation.
Chesapeake believes in investing in companies that have, at their core, responsible values and objectives. Many of our clients choose to invest in companies that align with their own specific interests and we support them in this endeavor.
As a company, we invest in corporations that demonstrate a commitment to the environment, have a reputation for high-quality products and services, and observe fair labor practices.
We do not buy the shares of tobacco companies or invest in companies that manufacture firearms.
We believe that this commitment is meaningful.
to learn more about our investment approach.