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HealthSurrogacy
Diwali Wishes from Canadian Family !!
Hi SCI family,
We want to wish you all a very happy and successful year ahead. May the Diwali festivities bring a lot of light, joy and cheer to your clinic for the whole new year and always.
Attached is a picture of Gabi and Leo. We celebrate Diwali every year as part of our family tradition.
Always thinking of you and our lovely surrogate mother.
Forever thankful,
Marina, Jesse, Gabi and Leo
HealthPregnancy
Effect of pollution on pregnant woman and the child and what can you do to avoid complications by Dr Shivani Sachdev Gour
Aapki Khabar Aapka Fayda, know how pollution is choking people to death. Watch the video to know more.
Conversation between Dr Shivani Sachdev Gour and ZeeBiz Anchor Anuiya Yadav
Dr Shivani Sachdev Gour Shared Views with JK24x7News about Sanitary Pad uses during Periods
Periods के दौरान इस वक्त Sanitary Pad बदलना जरूरी है . Female Specific Health Problem, JK24x7News discussed with Dr Shivani Sachdev Gour to Know about Sanitary Pad uses during periods- https://www.youtube.com/watch?v=zb-w57nfxWw&feature=youtu.be
dr shivani
Thankful Parents from India!!
Thank you for making it possible.
– Prisha & Amritansh
Dr Shivani Sachdev Gour ReviewsPregnancy
Grateful Parents from India!!
To all the lovely staff at SCI, We will always be grateful for your compassionate care and all the help we have received from you.
Special Thanks to Shivani Mam for her professionalism & thorough knowledge which was crucial for every step of our journey.
Thank you for making our dream comes true.
A Big Thanks,
Rachitusha
dr shivaniPregnancyTestimonials
Proud Parents from Afghanistan
Dear Dr. Shivani Gour,
I am really happy to share with you the good news that our baby was born. He is healthy and smart.
Millions of thanks to you who made this IVF cycle a miracle for us. All other doctors in India failed to do it. I'm proud of you and thank you a lot.
I really want to say that Dr. Shivani Sachdev Gour is the only perfect Doctor in India who solved my problem and changed my life. With the help of God she solved my problem and I became pregnant and I passed a successful pregnancy period. Other Doctors in India failed to do so.
My baby boy was born in Kabul on July 12, 2018. Thank you Dr. Shivani and wish you more success in your career.
Wish you more success.
Dr Shivani Sachdev Gour ReviewsTestimonials
Update from Australia !!
When Words are Not Enough
Dearest Dr Shivani Gour and Sumita Bhujel, You have made us the happiest parents in the world. Today we celebrate our daughter's 6th Birthday. THANK YOU!
Dr Shivani Sachdev Gour ReviewsIVF TreatmentSurrogacyTestimonials
Update from Canada, Thankful Message to Dr Shivani Sachdev Gour
Dearest Dr. Shivani,
We cannot thank you enough.
You have made our dreams come true, and given us a beautiful baby Boy.
We will always be grateful to you, your team and everyone that has brought us to parenthood. Please accept our deepest gratitude and know that we will always remember you and that you will always be a part of our family.
Angie + Scott + Baby Erik
Dr Shivani Sachdev Gour ReviewsIVF Treatment
Thank you SCI IVF Hospital
Dear Dr Shivani,
It's impossible to put into words our gratitude to you and your team. You have helped us to feel whole again and you will be in our hearts forever.
Thank you so much for helping to bring our precious angels for us i.e. Cian and Clava.
Much love to thanks
Lisa and Michael
IVF TreatmentUncategorized
IVF Treatment Centre in Delhi – IUI, ICSI, Surrogacy
1 IVF Treatment Centre in Delhi
1.1 What is Infertility & Why IVF Treatment Centre in Delhi?
1.2 Why IVF Treatment Centre in Delhi?
1.3 Is IVF Treatment Centre in Delhi Safe?
1.4 What about the baby?
1.5 IVF Treatment Centre in Delhi
1.6 What to look for before opting an IVF Treatment Centre in Delhi
2 Facilities and Services offered by SCI IVF Hospital & IVF Treatment Centre in Delhi
3 Is there any silver lining in opting for the IVF treatment Centre in Delhi?
4 Am I ready for IVF?
6 SCIIVF Hospital
IVF Treatment Centre in Delhi
IVF Treatment Centre in Delhi is in demand, as per the estimation 3 out of 10 couples suffer from infertility in Delhi and adjoining area.
What is Infertility & Why IVF Treatment Centre in Delhi?
One of the major survival instincts that all of the living creatures in this world possess is procreating. However, sometimes not everyone is fortunate enough to give birth naturally and in the current day and age of technology, due to changing lifestyle and habits, such conditions are only increasing. With the inconsistent food habit and the polluted air contributing their fair share to the increasing infertility among couples.
The chances of infertility among couples are also rising due increased work stress, a very hectic fast and furious urban lifestyle and environmental toxins.
Fortunately, infertility can be treated and advancements in the field of IVF (In-vitro-Fertilization) have become a boon for those seeking to have a young one of their own.
Why IVF Treatment Centre in Delhi?
IVF (In-vitro-Fertilization) is a well-known and accepted treatment to treat infertility among couples. In-Vitro translates to "outside the body", indicating that the whole procedure of fertilization takes place outside the body since the body appears to be incapable of producing a favourable environment for the fertilization to take place on its own.
In simpler terms, IVF treatment is aimed at assisting the procedure of fertilization by extracting the egg (ovary) from the female and the sperm from the male. The extracted egg and sperm are united in a very controlled and favourable environment in either a petri-dish or a test-tube under stringent supervision to ensure a very high chance of success.
Once the fertilization takes place, the union of egg and sperm pave way for the formation of an embryo. After around 3 to 5 days, once the embryo has reached sufficient development, it is obtained from the test-tube and carefully transferred into the woman's uterus. The embryo is expected to implant itself in the uterine lining and mature into the later stages.
Is IVF Treatment Centre in Delhi Safe?
The first successful IVF Treatment was performed in 1977, since then the world has been home to more than 7 million babies born out of this boon of a procedure. IVF Treatment is considered as a relativity safe and successful treatment. However, on rare occasions, complications have been observed and documented. It should be noted that technology has come a very long way and the standardization of the IVF Treatment ensures that complications and risks are mitigated quite early on during the course of treatment
What about the baby?
Now that we have addressed the safety of the procedure itself, the next big question that comes to mind is about the well-being of the baby. Couple who opt to go for IVF treatments are generally tormented by numerous questions and insecurities pertaining to the overall health of the resulting baby.
They are also almost always concerned about the cognitive development of the baby and if it will be able to perform tasks like any normal baby would be able to. The questions are also related how the mother will be affected by such a procedure and how different an IVF procedure would be compared to natural conception.
In conjunction with all these concerns, couples are also curious to know if IVF can result in natural deliveries or will it require medical intervention just the process of conception itself.
While all of these questions and concerns are extremely reasonable, the current development in the IVF treatments have negated most of the factors and it has become an extreme oddity for a new-born to be affected by cognitive disorders. In-fact the percentage of babies born with cognitive developmental disorders through the IVF treatments are no higher than the ones born from natural conceptions.
What are the possible risks in IVF Treatment Centre in Delhi?
IVF treatments have the potential to lead to multiple pregnancies, and if something like that occurs, there is a an increased risk of preterm delivery and low birth weight infant compared to singleton pregnancies. To negate problems like these, the current procedures used are focussed on single embryo transfer to ensure that there is only one live birth thereby eliminating any possibility of multiple pregnancies.
IVF Treatments in Delhi have witnessed a sizeable increase in the number of couples opting for the treatment in the recent years. Such an increase has led to the rise of the IVF centres around multiple places in Delhi. While the rise of IVF treatment centres in Delhi might be a boon, there are some aspects about the treatment centres which should be primarily considered before picking one.
What to look for before opting an IVF Treatment Centre in Delhi
Before opting for an IVF Treatment Centre in Delhi, it is important to look into the success rates of the centres providing these treatments. While there is a small degree of chance that a particular centre may exaggerate their success rate, hence it is recommended to verify the success rates of the IVF centres in Delhi with reputable sources. The feedback from patients would also be of immense use in deciding which centre to opt for and initiate the treatment.
The portfolio of medical experts, an IVF centre can offer should also be considered as an important factor since adequate knowledge and experience in the field is most crucial in ensuring correct treatment in timely manner and avoiding unnecessary complications. Timing is also key and ensuring that the clinic always focusses on maintaining schedule can be a very easy way of splitting the good ones from the mediocre ones.
While assessing the Success rate and Medical expertise of an IVF Treatment in a Delhi clinic, it is also important to place an emphasis on the cost of the treatment. Cost of the treatment is individualised as every couple is different and their fertility issue is also different.
There are clinics which IVF Treatment Centre in Delhi that cost much lower than the majority of other clinics and their portfolio might appear promising as well. However, it is important for a couple to verify the success rate and the medical expertise of the said clinic with some reputable sources before taking the plunge. While the cost is an extremely important factor, it shouldn't be a deciding one when lives are at stake.
For couples looking to get treated in a good hospital with a proven track record, SCI IVF Hospital looks like a fantastic value proposition. The hospital is committed to delivering high success rates while still being affordable.
SCI IVF Hospital is one of the few reputable IVF treatment centres in Delhi. The centre has consistently produced excellent results with its IVF treatments and is renowned for its high success rate. SCI IVF Centre is located at Kailash Colony in South Delhi and took its first step into the industry in 2011. It has since been a birthing place to over 1200 babies who were conceived with the help of advanced IVF treatments to couples suffering from infertility.
Dr. Shivani Sachdev Gour is the founder and director of the SCI IVF Healthcare Centre, she also serves as a Healthcare and consultant fertility specialist. She completed her speciality training and graduation in Gynaecology and Obstetrics from Mumbai and was trained in IVF treatments for fro four years in the UK at Hammersmith Hospital situated in London and the Royal Infirmary of Edinburgh situated in Scotland. Collectively she has practiced as an obstetrician and gynaecologist, and as an infertility specialist for over 12 years. Her immense experience and knowledge in the field is directly fed into the core morals and philosophies of the SCI IVF hospital.
The hospital is also home to a large team of doctors, medical professionals, lawyers and support staff who are always available to assist the patient in every way possible to ensure their comfort and peace of mind. The Hospital is also extremely transparent about its operations and procedures, it has even gone so far as to publish all the certification and accreditation it has received in its official website.
https://www.sciivf.com/about-sci/certifications/
Facilities and Services offered by SCI IVF Hospital & IVF Treatment Centre in Delhi
SCI IVF Centre is equipped with the cutting-edge technology in infrastructure and IVF treatments to provide a comprehensive fertility service to both male and female patients. The hospital is also ISO 9001:2008 accredited and follows the strict guidelines and policies of the Indian government.
All the procedures and treatment offered by SCI IVF Centre are standardised and adhere to the protocols laid down by ICSI to ensure compatibility with the rest of the advanced IVF treatment centres. This also ensures that the couples opting to continue an already undergoing treatment from a different hospital can make a seamless transition into the SCI IVF Centre.
SCI IVF Hospital offers a comprehensive list of services to treat infertility and here is a list of what the centre offers:
IVF / ICSI Treatment
This treatment is focussed on the procedure by which an egg is fertilized outside the body by the sperm as is considered as a classic IVF treatment. The procedure involves the use of fertility hormones in order to stimulate the woman's ovaries to produce healthy eggs which will be used for the IVF treatment. The eggs are then removed under stringent monitoring and under the influence of an anaesthetic to ensure the procedure is as painless as possible. The removed egg is fertilized with the partner sperms and the resulting embryo is cultured for 2 to 6 days in a controlled environment and transferred to the patient's uterus to establish a successful implantation and thereby ensuring that the patient is successfully impregnated with the baby.
Male Infertility is the underlying problem in about 30 – 40 percentage of couples suffering from the inability to conceive. Male infertility can be caused by a number of factors ranging from immobile sperm, low count/ sluggish sperm, misshapen sperm or even blockage within the male genitalia that prevent the delivery of sperm. Injuries, chronic health problems, illness or even lifestyle choices can have a huge impact on the male fertility. SCI IVF offers treatments focussed on comprehensively analysing the type of infertility and targeting the recovery of the damaged factor.
Ovarian Induction
This procedure involves using injections/ tablets to stimulate the ovaries which produce "follicles". These follicles would then contain the supposed healthy egg. The eggs are kept under constant supervision and triggered at the appropriate time with the help of a trigger injection which would then release the eggs. This type of ovarian induction maximises the chances of getting pregnant by focussing on ensuring that the eggs required for fertilization is available to the sperm at the right time. This assisted approach is used in couples who find it difficult to conceive, but appear to be quite healthy otherwise.
This procedure is primarily focussed on women over 35 years of age and in case of frozen embryos. Sometimes when IVF/ ICSI treatments fail repeatedly, the procedure can be augmented with the use of a Laser Assisted Hatching. The procedure focusses on drilling a small hole in the shell of the embryo to better aid its expulsion and thereby impregnantion.
This method is one of the widely used assisted conception procedures in India. The procedure focusses on obtaining the sperm from the male and preparing it. The sperm is then directly placed in the uterus around the time when the ovary releases one or more eggs. This maximises the chances of fertilization and therefore conception. The simplicity of the procedure is only complemented by its success rate which is usually very high.
This procedure is centred around enhancing the implantation potential of an embryo. The embryos are initially cultured in a special fluid medium under controlled conditions for around 5 to 6 days. Once the embryo reaches a stage where it comprises of at least 200 to 300 cells, it is considered as a robust embryo. This robust embryo is then transferred into the uterus for implantation. The success rate of this procedure is high owing to the high implantation potential of the cultured robust embryo.
In certain men, the main cause of infertility is the lack of adequate sperm in the ejaculate. While these men can produces enough sperm in the testes, due to certain medical conditions, their ejaculate do not seem to carry these sperms over. In such a scenario, these produced sperms are collected by surgical sperm retrieval techniques and used for insemination. This technique is also used for people who suffer a failed vasectomy reversal, giving them an option to procreate.
Embryo Biopsy for PCD\ PGD
This procedure is focussed on retrieving single or multiple cells from a human embryo. The removed cells are then sent for genetic analysis. However, this procedure strictly only offers screening for genetic disorders in the embryo and does not reveal the sex of the infant, since sex selection is banned in India. This technique is used in conjunction with the IVF treatment to ensure that the new born is free of any potential genetic disorders.
The excess embryo retrieved from an IVF/ ICSI cycle can be frozen in liquid nitrogen at negative 196 degrees. The frozen embryos can serve as a good back up plan in case the first session of IVF treatment fails. It can also be used if the parents are keen for a sibling at a later point in time. The freezing of these embryos is performed by the new/ fast freeze or vitrification technique in SCI IVF Hospital & Surrogacy Centre India.
Egg donation is the procedure where an egg from a healthy young fertile woman is used to create an embryo for another woman who has poor quality eggs or an ovarian failure.
Is there any silver lining in opting for the IVF treatment Centre in Delhi?
Yes, there is a silver lining to the IVF treatment compared to natural conception and it's a big one. IVF treatments can include screening of genetic disorder to identify if the selected embryo or sperm contains a potential disorder. While such a screening is not mandatorily performed, it can be requested by the couples or prescribed by the doctor. Such a screening is generally recommended if any disorder is identified in the lineage of either of the parents such as muscular dystrophy or cystic fibrosis. The screening procedure is known as Pre-implantation Genetic Diagnosis or PGD for short. PGD is also a very effective way to ensure that the conceived baby will not carry the potential disorder.
Pre-Implantation Genetic Screening or PGS is yet another effective procedure used to ensure a high success rate for IVF treatments. PGS mainly increases the chances of a successful pregnancy. PGS is focussed on screening the embryos for chromosomal disorders. Hospitals like SCI IVF in Delhi are adequately-equipped with the infrastructure and expertise to carry out these intricate procedures. The specialists of these hospitals are also generally quite approachable and give them much needed assurance and comfort to the couples.
Am I ready for IVF?
While the type of infertility between a couple can be assessed by physical analysis to ensure that IVF treatments can help them, the emotional state of a couple can only be assessed by themselves. From a strictly physical standpoint, if the embryo and sperm of the couples are healthy and the body of the female can sustain and carry out a pregnancy, she is ready for an IVF treatment.
But from an emotional standpoint, it is solely at the discretion of the couples. But nevertheless, the hope and happiness IVF brings along with it to offer to the couples who through a period of unhappiness and despair cannot be disregarded. IVF treatments help the couples experience the joy of parenthood.
In case you require any further information on infertility and its various treatments. Please let us know, We would be glad to answer your queries.
For further authority on this information please find enclosed the some of the panel discussion at NDTV, RajyaSabha and Testimonials from patients.
A-1, Kailash Hosptial
Greater Kailash, New Delhi-18, New Delhi
www.sciivf.com
A Heart Touching Thankyou Card for Dr Shivani Gour & SCI IVF Centre
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Sudan general says paramilitaries killed students
Thursday August 1 2019
Sudanese students protest in the capital Khartoum on July 30, 2019, a day after teenagers were shot at a rally against shortages of bread and fuel in the town of al-Obeid. PHOTO | EBRAHIM HAMID | AFP
Six protesters including four school children killed were shot dead a rally this week.
Military council accused members of the feared paramilitary Rapid Support Forces (RSF) of firing at the rally.
Sudan's official news agency Suna reported that the accused have been handed over to authorities in North Kordofan state.
A top Sudanese general has said the six protesters including four school children killed at a rally this week were shot dead by members of a feared paramilitary force.
Tragedy struck Sudan's central city of Al-Obeid on Monday when the protesters were shot dead during a rally against a growing shortage of bread and fuel in the city.
General Jamal Omar from the country's ruling military council accused members of the feared paramilitary Rapid Support Forces (RSF) of firing at the rally.
The rally was initially stopped with batons by a group of RSF forces who were guarding a nearby bank, the general told reporters in the city late Wednesday, quoted by Cairo-based Al-Ghad television network.
"This action led to a reaction from some students who threw stones at the forces," Omar said.
"This made some members of the force act in their individual capacity to open fire on protesters. We have identified those who fired live ammunition that led to the killing of the six."
They were sacked following orders from the RSF command and would face trial, it said.
RSF is headed by General Mohamed Hamdan Dagalo, who is also deputy chief of Sudan's ruling military council that seized power after the army ousted longtime president Omar al-Bashir in April.
Protest leaders have consistently accused the RSF of using excessive violence against demonstrators since the generals seized power.
An official investigation had found three senior RSF officers involved in the brutal dispersal of protesters in a raid on a weeks-long sit-in in Khartoum on June 3.
Doctors linked to the protest movement said 127 people were killed in the raid. Officials have given a much lower death toll.
Daglo has denied such accusations against the RSF, saying it was an attempt to distort the image of his force.
The RSF has its origins in Arab militias that were originally deployed by Bashir's government to suppress an ethnic minority rebellion that erupted in the western region of Darfur in 2003.

redpajama_set_name: RedPajamaCommonCrawl


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Three's Company: "Design for Living," at the Village Theatre through June 15
Design for Living, which Scott Community College is currently presenting at the Village Theatre, is a quick-witted Noël Coward comedy concerning an interior decorator (Bri Kenney's Gilda) who finds her romantic affections torn between a struggling artist (Randy Langtimm's Otto), and a struggling playwright (J.W. Hertner's Leo). It is also, by a considerable margin, the most engaging of the three Scott productions I've seen since November, and while I'm not usually the type to bestow awards, I want to begin by praising three facets of Saturday's presentation that might easily stand as theatrical "bests" of 2008.
· Best use of a natural set piece. Coward's play opens in a Parisian flat in 1933, where Bri is conversing with her art-dealer confidante, Ernest (Daniel Schaub). At one point, Ernest asks for more light in the room, and Bri goes to the curtains hanging on the back wall, opens them, opens the window shade, and - well, I'll be ... ! - actual, honest-to-goodness sunlight shines in though a window conveniently built into the rear of the Village Theatre's stage. This unexpected blend of theatrical life and real life made me want to applaud.
· Best accident that may not have been an accident. After Bri's first scene with Otto, with whom she's been having an affair, the artist leaves the stage, and Leo - who's been hiding in the bedroom - enters. On Saturday, Hertner got his suit jacket caught in the bedroom door as he closed it behind him, but instead of re-opening the door and releasing his jacket, he simply removed it, left it dangling from the door jamb, and continued the scene. The audience snickered at the presumed goof, yet I'm not sure it was a goof; later, when Otto re-enters and Leo is forced to reveal his affair with Bri, he does so in the subtlest way imaginable - by returning to the bedroom door and apologetically removing the jacket. ("Oh," says Otto. "I see.") If the trapped-coat moment was an accident, it was a brilliant accident. If it wasn't, then it was merely brilliant.
· Best consumption of liquids. As Design for Living is a Noël Coward piece, you can bet your badinage there's going to be drinking. But in Act II, after Bri has left identical "Dear John" letters to her two suitors, the abandoned Leo and Otto decide to drown their sorrows in glasses of brandy. Then they have two more. And then two more. And when the bottle is empty, they move on to the sherry. All told, the actors down (I'm estimating) more than a liter's worth of faux booze in roughly five minutes, and do so without so much as a belch. Coward would've been proud.
I'm guessing he would've been proud of much of Design for Living, because beyond the aforementioned minor pleasures, Scott Community College's production offers a major one in its representation of the playwright's delightfully epigrammatic style. The work isn't without psychological complexity; Coward's piece, after all, offers a ménage a trois as a perfectly viable and, for these characters, even healthy romantic option. But in director Steve Flanigin's take on the material, the more thought-provoking elements are kept where they should be kept - as enjoyably eyebrow-raising subtext. (Interpret how you will the moment when Leo and Otto enter from the bedroom, with Otto wearing the top half of pajamas and Leo wearing the bottom half.)
Instead, the focus is rightfully placed on Coward's genius at blending high and low comedy - Esther Clement is a hoot as a surly maid with an ever-present cigarette drooping from her lips - and witticisms that zip by almost faster than you can register them. Certainly, that's often the case here; several cast members, particularly Kinney and Hertner, spit out their British-accented remarks so hastily that catching them all would be a Herculean undertaking. (The show runs two hours and 40 minutes, but not because of any lapses in tempo.) Her speed, though, is the finest thing about the lovely Kinney's performance here - her funniest quips tend to detonate two seconds after she's uttered them - and the gifted Hertner is at his best when Leo's edgy discomfort shifts to manic apoplexy.
Among an enthusiastic ensemble that includes Sara Bolet, Stephanie Hamilton, and an impressively double-cast Chris Wadsager (who, without help from the program, I wouldn't have known was double-cast), the empathetic, committed Schaub provides both resigned acceptance and intimidating, volatile rage, and Langtimm, who appears to love acting, delivers a sequence of wounded heartbreak that is easily the finest work I've yet seen from him. He still offers expert comic timing - even though his busy facial expressions too often steal focus from Schaub in the play's final scene - but I was thrilled to watch Langtimm emerge as an equally dynamic dramatic presence, and would like to see his stab at more tragic roles down the road. Maybe Brick in Cat on a Hot Tin Roof - Lord knows, after Design for Living, the man can handle his (on-stage) liquor.
For information, call (563) 441-4339.
Village Theatre
Scott Community College
Steve Flanigin
J.W. Hertner
Esther Clement
Daniel Schaub
Bri Kenney
Randy Langtimm
Stephanie Hamilton
Chris Wadsager
Sara Bolet
Mike Schulz
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Designed in collaboration with Stella McCartney, this adidas STELLASPORT Mesh women's gym sack is perfect for the gym and for your free time.
Designed in collaboration with Stella McCartney, this adidas STELLASPORT Mesh women's gym sack is perfect for the gym and for your free time. It features shoulder straps which double as lacing closure and an allover print with adidas STELLASPORT logo. Dimensions: 39 cm x 49 cm. Composition: 100% polyester.


My name is Romain Etchegoyhen. I am 29 and I live in Lyon. I am a Creative Developer. I am passionate about design and user experience. When I am not making the web, I am a happy husband and dad.
I started my career in a start-up specialized in robotics. We built a small robot to help students learn how to code in a fun and playful way.
In 2013, I left the company to create my own development agency with Sylvain. For two years we worked with talented people on challenging and ambitious projects. We designed and developed more than 15 websites and mobile apps for a dozen of clients from at least 5 different countries.
Our most popular app has been downloaded over 100000 times. We won an award for our work on Den Danske Ordbog (a Danish dictionary) at the Danish App Awards 2013 in the News & Reference category.
I am now working at @Nexenture as a Creative Developer and I am not available for freelance work.


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Ben Jacklin, Author at Consordini.com
Ben is a writer, musician, and former studio engineer from the UK. His two major passions in life are music and writing, so naturally, he chose a combination of both as his career. Besides writing about instruments, music, and music equipment, he also used to work in recording studios in the East of England. He produced music that has been played on BBC radio and even ran a record label where some of the music he produced was played on MTV.
The self-proclaimed audiophile
As a self-proclaimed audiophile, Ben emerged himself in the world of music from quite an early age. He got a National Diploma in Music Technology and plays several instruments himself. He started working in a photography studio after graduating, but eventually found his way back to the music industry when he started tutoring for a music and mental health organization - Noise Solution.
At around that time he also started to write more professionally. He had been writing for publications in some form or another since he was a teenager, and was always obsessed with telling stories, but at this time he decided to make a career out of it.
Becoming a writer
For the past 5 years, he has been writing full time, covering a lot of topics in two major industries - music and technology. Combining all his experience, skills, and knowledge with his unquestionable writing skills, he produces content that is engaging, informative, and also easy to understand.
Ben still produces some music, but his main focus now is on writing and educating about the topics he is passionate about. He delivers well-researched and on-point reviews and guides on instruments and equipment that he worked with for years - so his readers always get information that is true, unbiased, and usually also gathered from his own first-hand experience.
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The 8 Best Podcast Microphones 2023
is a great time to start a podcast, you don't even need much equipment, but you need one of the best podcast microphones, and this guide is designed to show you some of the best options and what you should consider when it is time to buy a podcast mic.


CXCR4 and CXCR7 will be the two receptors for the chemokine CXCL12, an integral mediator from the growth aftereffect of estrogens (E2) in estrogen receptor (ER)-positive breasts cancers. the development aftereffect of E2. These results suggest that E2 legislation from the CXCL12 signaling axis is normally very important to the E2-mediated development effect of breasts cancer tumor cells. These data provide support for distinctive biological features of CXCR4 and CXCR7 and claim that concentrating on CXCR4 and/or CXCR7 could have distinctive molecular results on ER-positive breasts tumors. Launch Estrogens, notably 17–estradiol (E2), play an essential function in the control of epithelial cell proliferation as well as the differentiation of regular mammary gland cells aswell as in breasts carcinomas. The consequences buy PH-797804 of E2 are mediated principally by nuclear estrogen receptors alpha (ER) and beta (ER). ER is normally portrayed in 70% of diagnosed breasts malignancies , . In ER-positive breasts cancer tumor cells, E2 stimulates cell development and is important in tumor development . The proliferative aftereffect of E2 could be repressed using anti-estrogens utilized medically in hormono-therapy . Furthermore, ER-positive breasts tumors look like more differentiated and appearance to metastasize significantly less than buy PH-797804 ER-negative breasts tumors , . Therefore, the manifestation of ER in breasts tumors is normally regarded as an sign for an excellent prognosis. Although latest works reported the expression of several genes are controlled by E2 in ER-positive breasts cancer cells, small is well known about their part in E2-development impact , . The chemokine CXCL12 (also called SDF-1 for Stromal-cell Derived Element 1) was defined as an integral mediator of E2-induced breasts tumor cell proliferation and success , . This chemokine offers several well-known features: (i) in cell migration during embryonic advancement, (ii) in the chemotactism of circulating leucocytes and (iii) in the homing of hematopoietic stem cells in bone tissue marrow niche categories , . Furthermore, CXCL12 regulates the homeostasis, angiogenesis, proliferation, success and migration of tumor cells , , . The G Protein-Coupled-Receptor (GPCR) CXCR4, an E2 APAF-3 endogenous focus on in endometrial tumor cells , binds CXCL12. The high manifestation of CXCR4 continues to be often connected with an intrusive and migratory phenotype of tumor cells , . Metastatic breasts tumor cells extremely expressing CXCR4 are usually within organs such as for example liver organ, lung or bone tissue. This suggests a privileged homing, success and proliferation of metastatic breasts tumor cells to these particular sites, where in fact the regional secretion of CXCL12 is definitely solid , , . Knockdown of buy PH-797804 CXCR4 by buy PH-797804 siRNA or blockage of CXCL12 binding having a CXCR4 particular neutralizing antibody or particular CXCR4 inhibitors impairs the proliferation and migration potential of the metastatic cells , . Until lately, the ligand/receptor few CXCL12/CXCR4 was regarded as exceptional because and mice acquired very similar prenatal lethal phenotypes . CXCL12, nevertheless, may also bind CXCR7, an orphan GPCR also known as RDC1 , . Developing evidence indicates a job for CXCR7 in cancers cell proliferation and migration , , , . The comparative expression degrees of CXCR4 and CXCR7 could be vital to regulate how the cell will react to CXCL12. Actually, recent studies show that heterodimerization of the two receptors modulates the mobile response to CXCL12 , , . Within this research, we analyzed the regulation from the CXCL12/CXCR4/CXCR7 axis and its own participation in the proliferation and success of E2-reliant and -unbiased breasts cancer tumor cells. Our outcomes showed which the E2-reliant up-regulation of CXCL12 and CXCR4 that's connected with a down-regulation of CXCR7 could possibly be pivotal for E2-induced development of breasts cancer cells. Components and Strategies 1. Antibodies and reagents The antibodies employed for the Traditional western blot assays had been rabbit polyclonal (Rp) antibody against CXCL12 (sc-28876; Santa Cruz Biotechnology, Heidelberg, Germany), Rp antibody against CXCR4 (ab2074; Abcam Inc., Cambridge, UK), Rp antibody against CXCR7 (stomach12870; Abcam Inc.) and Rp antibody against ERK1 (sc-94; Santa Cruz Biotechnology). The antibodies employed for FACS had been murine monoclonal (Mm) antibody anti-human CXCR4 (clone 12G5, R&D Systems) and Mm antibody anti-human CXCR7/RDC1 (clone 11G8, R&D Systems, Minneapolis, MN, USA). All reagents employed for treatments.


Witness equestrian at its finest.
As the fifth Boneo Classic came to an end, the management team shared feelings of pride and satisfaction for a job well done. This was a milestone event that brought together many ground breaking changes to the conventional event management model, setting new standards by combining multi disciplined competition, hospitality and commerce in an all-inclusive approach that was enthusiastically received.
Above: Back row left to right: Scott McNaught, Director of Boneo Park and Jumping Manager. Aengus Wright: Sound and Commentary, Stephanie Wake: Marketing Manager.
Front row left to right: Karen Lawrence, Director of Boneo Park and Competition Manager. Lizzy Schirmer: Dressage Secretary, Fiona Selby: Managing Director Boneo Park. Justine Quayle: Event Team Boneo Park – volunteer and stabling manager.
"I would also like to thank the grounds maintenance team, their work in the presentation of the complex and fastidious grooming of all competition surfaces, as this enables us to meet the best practise standards for each sport.
Boneo Park works closely with Paton's Machinery for the supply and maintenance of equipment.
The Australia Day weekend gave competitors, spectators and traders a wonderful celebration of equestrian sport, friendship and fun and brought together the best jumping, dressage and para-equestrian combinations to take part in a comprehensive program of classes up to international level.
The expansion of Boneo Park has allowed some innovative changes to the format of the 5th Boneo Classic. The para-equestrian classes took place in the indoor arena, with jumping and dressage showcased on discipline specific facilities that share a central hospitality area that is designed to foster cooperative interaction.
April 2019 will see the opening of Arilla, the upper level restaurant that overlooks both main arenas and will be open to the public all year round. Competitors and spectators were unanimous in their praise of this innovative approach and the future possibilities!
The specialist, state-of-the-art competition surfaces are discipline specific and have been designed, engineered and purpose built by Martin Collins to meet best world standards. The main showjumping arena is considered to be one of the best grass jumping surfaces in Australia! Not only did the beautiful expanse of green make for a picturesque setting, it stood up to the high traffic of 500 rounds ridden over three days.
A great deal of work behind the scenes has taken place to comply with the FEI's stringent requirements to host a jumping World Cup Qualifier and to run a prestigious World League Final for dressage. The Boneo Park bid was approved and this was largely attributed to the vision and expertise of dressage supporter Deb McNicol, her tireless efforts and success were acknowledged at the Grand Prix CDI-WLF Freestyle presentation ceremony.
Pic: CDI-WLF top three are congratulated by chair of the Ground Jury Susie Hoevenaars (right) Deb McNicol centre.
Thirty specialist traders added interest and wide variety to those in need of some retail therapy, and the inclusion of entertainment for adults and the younger fans created a non-stop festival atmosphere. 2,500 visitors came through the gates over three days and numbers are sure to grow as the word gets out and people reserve Australia day weekend for the Boneo Classic.
Fiona Selby said, "The success of the Boneo Classic relies on teamwork that comes together in the spirit of goodwill and generosity. I would like to take this opportunity to acknowledge the valued support of our sponsors, we could not stage this event without their help and it has been uplifting to work with them, listen to ideas, and come up with a program that supports their business activities.
The Boneo Classic attracts Australia's top jumping, dressage and para-equestrian combinations and this is a win/win/win, as successful riders inspire participation, which grows the fan base with a flow on effect to professionals and suppliers of equine products and services.
Since the FEI's inclusion of para-equestrian in 2006, this arm of the sport has grown significantly and Australia was proud to win Olympic gold in 2012. A strong contingent (including London winner Joann Formosa) took part and showcased their abilities to a wider audience.
Para-Equestrian riders share friendship and fun at the Boneo Classic.
Australia celebrates the winners of the two main events; their Boneo Classic success puts them in strong contention to represent Australia at the 2010 Tokyo Olympic Games. Seeing them in action was a real thrill for everyone that packed the stands.
The IRT Dressage Grand Prix CDI-WLF saw a resounding win go to NSW rider Rozzie Ryan, partnered by her elegant chestnut Jarrah R. Even though she no longer owns Jarrah R, one can only imagine Rozzie's pride and reflection, as he was bred at Ryan's Horses and was sired by Jive Magic (by Jive), her former Grand Prix partner.
The pair won Saturday's Grand Prix test and went on to win the deciding Freestyle to Music, gave Rozzie the opportunity to step into her comfort zone, riding to music she chose and arranged to fit with her own choreography that so beautifully suited her dancing partner. It was a light and ethereal performance that resoundingly confirmed the harmony and ease of this performance. The 5 judges awarded a wonderful score of 72.710%.
Congratulations to the runner up Holly Cutler who rode her lovely imported mare Diva Royale to score 68.695% just ahead of Rio Olympian Sue Hearn and Remmington on 68.180%.
Full dressage and para-equestrian results can be found at http://equiscore.com.au/?page_id=1001. Boneo Park will progressively add pictures to their web site so refer back periodically.
Huge jumping entries promised to make the three day program a special gathering of riding and non-riding fans. The bright green perfectly manicured grass, along with the colourful and creative jump wings and poles, were peppered with strategically placed Audi Mornington vehicles. A wonderful display that made for a picture perfect setting, and the performances were in keeping with the ambiance.
Course designer David Shepherd is well respected for his knowledge and skill, his track gave the riders' appropriate challenges but not at the expense of appropriate safety considerations. The height of obstacles at World Cup level seem to pose an impossible dream, but the athleticism and ease shown by these experienced campaigners, is a jaw dropping testament to the years of training, which gives them confidence and trust in their rider.
David Shepherd steps out the World Cup distances before approving the course for a start.
The final round of the Robertson-Smith Partners World Cup Qualifier saw a number of riders with a chance at success but the added dimension of speed combined with accuracy and timing brought forward the eventual winner. Queensland's Billy Raymont and Anton made it look easy, but the knowledgeable capacity crowd understood the significance of this internationally recognised achievement.
Pic: World Cup Qualifier winner Billy Raymont aboard Anton is congratulated by Veterinarian Glenn Robertson-Smith and his associates, who were proud sponsors of the class and provide ongoing support to performance horses, with the latest technology for correctly diagnosing lameness.
Second place went to Andrew Lamb and CP Argento, they jumped clear in 55.70 seconds. A disagreeable rail proved costly for the third placegetter Steven Hill and the imposing Yalambi's Bellini Star. They jumped convincingly and fast, recording a time of 49.95 but the 4 penalties gave Lamb the advantage.
Clay Simmonds and Oaks Castanza recorded the fastest time in the final round, 47.46 seconds. Starting the decider with 4 penalties on the scoreboard, they needed luck to overtake the horses that had jumped clear, but it was not to be!


text:
La diocesi di Morombe (in latino: Dioecesis Morombensis) è una sede della Chiesa cattolica in Madagascar suffraganea dell'arcidiocesi di Toliara. Nel 2021 contava 53.769 battezzati su 711.850 abitanti. La sede è vacante.

Territorio
La diocesi comprende i distretti di Manja, Ankazoabo, Beroroha e Morombe nella provincia di Toliara in Madagascar.

Sede vescovile è la città di Morombe, dove si trova la cattedrale del Sacro Cuore di Gesù.

Il territorio è suddiviso in 17 parrocchie.

Storia
La diocesi è stata eretta il 25 aprile 1960 con la bolla Africae gentes di papa Giovanni XXIII, ricavandone il territorio dalla diocesi di Morondava.

Il 3 dicembre 2003 ha cambiato metropolia, passando dalla provincia ecclesiastica dell'arcidiocesi di Fianarantsoa a quella dell'arcidiocesi di Toliara.

Cronotassi dei vescovi
Si omettono i periodi di sede vacante non superiori ai 2 anni o non storicamente accertati.
 Joseph Zimmermann, M.S.F. † (28 maggio 1960 - 4 dicembre 1988 deceduto)
 Alwin Albert Hafner, M.S.F. † (15 maggio 1989 - 15 luglio 2000 dimesso)
 Zygmunt Robaszkiewicz, M.S.F. (24 aprile 2001 - 19 novembre 2022 nominato vescovo di Mahajanga)

Statistiche
La diocesi nel 2021 su una popolazione di 711.850 persone contava 53.769 battezzati, corrispondenti al 7,6% del totale.

|-
| 1970 || 11.924 || 145.006 || 8,2 || 18 ||  || 18 || 662 ||  || 21 || 19 ||
|-
| 1980 || 14.889 || 145.000 || 10,3 || 19 ||  || 19 || 783 ||  || 22 || 18 ||
|-
| 1990 || 20.682 || 189.387 || 10,9 || 12 ||  || 12 || 1.723 ||  || 14 || 21 ||
|-
| 1996 || 27.900 || 280.400 || 10,0 || 12 ||  || 12 || 2.325 ||  || 13 || 32 ||
|-
| 2000 || 27.410 || 276.022 || 9,9 || 14 || 1 || 13 || 1.957 ||  || 14 || 43 ||
|-
| 2001 || 30.237 || 375.015 || 8,1 || 16 || 1 || 15 || 1.889 ||  || 16 || 44 ||
|-
| 2002 || 31.206 || 387.263 || 8,1 || 15 || 1 || 14 || 2.080 ||  || 15 || 43 ||
|-
| 2013 || 39.507 || 554.000 || 7,1 || 28 || 15 || 13 || 1.410 ||  || 15 || 38 || 12
|-
| 2016 || 42.922 || 660.509 || 6,5 || 32 || 20 || 12 || 1.341 ||  || 15 || 36 || 13
|-
| 2019 || 51.846 || 686.843 || 7,5 || 39 || 27 || 12 || 1.329 ||  || 22 || 37 || 16
|-
| 2021 || 53.769 || 711.850 || 7,6 || 41 || 27 || 14 || 1.311 ||  || 28 || 37 || 17
|}

Bibliografia
 Bolla Africae gentes, AAS 53 (1961), p. 18

Collegamenti esterni
Annuario pontificio del 2022 e precedenti, in
 Scheda della diocesi su www.gcatholic.org

Morombe
Morombe

redpajama_set_name: RedPajamaWikipedia


Photo of "The Healer" by Brisan. Accessed through Flickr and available through the Creative Commons license.
"Doctors?" said Ron looking startled. "You mean those Muggle nutters that cut people up? Nah, they're healers!"
I both love and hate these words of Ron Weasley evaluating the limitations of Muggles like me and our ability to get each other well. On the one hand, I like his recognition that not all healing comes at the edge of the scalpel or the sharp end of a needle.
On the other hand, I love my doctor. I do. She saved my life twelve years ago when she diagnosed me with postpartum depression after the birth of my son. She immediately started me on anti-depressants and referred me to a postpartum psychologist for a follow-up evaluation. And she always included my mood as part of the postpartum checkups after I gave birth to my three subsequent children, keeping close tabs on me to make sure things weren't going sideways. Thankfully, they didn't.
This year, my doctor was my healer in so many ways: putting me on medical leave; making sure I was on the right dose and type of medication; getting me into a free, provincial cognitive therapy program. And, at every follow-up appointment, she asked not only about my mood but my ability to manage things at home, ensuring that I had what I needed to cope with my life as a mom of four.
So yeah, I'm going to disagree with Ron and assert that my doctor is a healer. But as much as I think my doctor is a healer, I know that healing doesn't end with her, nor can the praiseworthy title of healer be given only to her. There are other people, professional and otherwise, who have brought healing in my life not only in this past year but throughout my life. So in their honour, and in honour of the many other healers at work around the world, I'd like to offer up this poem of thanksgiving. See if you can find your own healers in it or even, yourself--not for me, necessarily, but for someone else.
The counsellors and coaches, therapists and clinicians.
O Lord, we give You thanks.
The friends, the family, the neighbours, the clergy.
Who call to check in or take our kids to the park.
The schools, the workplaces, the neighbourhoods, the congregations.
The spouses, the girlfriends, the boyfriends, the best friends.
For those who hold fast when we are broken, who speak hope into our despair.
Happy Canadian Thanksgiving, friends. Richest blessings to each and every one of you.


ACS Chem Biol. 2013 Mar 15;8(3):626-35. doi: 10.1021/cb300604u. Epub 2012 Dec 26.
Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules.
Guo Y1, Partch CL, Key J, Card PB, Pashkov V, Patel A, Bruick RK, Wurdak H, Gardner KH.
Departments of Biophysics, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8816, USA.
For several well-documented reasons, it has been challenging to develop artificial small molecule inhibitors of protein/protein complexes. Such reagents are of particular interest for transcription factor complexes given links between their misregulation and disease. Here we report parallel approaches to identify regulators of a hypoxia signaling transcription factor complex, involving the ARNT subunit of the HIF (Hypoxia Inducible Factor) activator and the TACC3 (Transforming Acidic Coiled Coil Containing Protein 3) coactivator. In one route, we used in vitro NMR and biochemical screening to identify small molecules that selectively bind within the ARNT PAS (Per-ARNT-Sim) domain that recruits TACC3, identifying KG-548 as an ARNT/TACC3 disruptor. A parallel, cell-based screening approach previously implicated the small molecule KHS101 as an inhibitor of TACC3 signaling. Here, we show that KHS101 works indirectly on HIF complex formation by destabilizing both TACC3 and the HIF component HIF-1α. Overall, our data identify small molecule regulators for this important complex and highlight the utility of pursuing parallel strategies to develop protein/protein inhibitors.
a. Schematic of HIF complexes, which are bHLH-PAS heterodimers that include an O2-sensitive HIF-α subunit and a constitutive ARNT subunit. Under normoxia, O2-dependent hydroxylation of HIF-α decreases its abundance and activity. Hypoxia stops these modifications, allowing HIF-α to accumulate in the nucleus and dimerize with ARNT. This heterodimer binds to hypoxia responsive enhancer (HRE) sites, controlling target gene transcription. In addition to binding HIF-α, ARNT PAS-B directly recruits CCC proteins., b. Structural model of an ARNT/CCC complex showing how the TACC3 coiled coil interacts with the helical surface of ARNT PAS-B, opposite from where HIF-α PAS-B binds.
a. Diagram of the ARNT PAS-B crystal structure, shown inset with secondary structure designations and internal cavities (grey mesh). The larger cavity is adjacent to the TACC3 binding site and contains three waters; the.smaller cavity is primarily hydrophobic. b. Schematic of the NMR-based screen for compounds that bind ARNT PAS-B. Initial 15N/1H HSQC spectra were acquired with 250 µM 15N-labeled ARNT PAS-B with a mixture of five compounds (1 mM each); mixtures producing large chemical shift perturbations (compared to DMSO) were deconvoluted as shown. c. Lead compounds (500 µM each) from NMR-based screen were tested for their ability to disrupt complexes of ARNT PAS-B with CCC fragments of TRIP230 (1583–1716) and TACC3 (561–631 = TACC3-CT). d. Summary of ARNT PAS-B binding and ARNT/CCC disruption of tested compounds. All ten compounds generated chemical shift perturbations when titrated into ARNT PAS-B; KG-548 and KG-655 (red box) also disrupted TRIP230 and TACC3 binding to ARNT PAS-B in vitro.
a. 15N/1H HSQC spectra of a KG-548 titration (0–1 mM from light to dark crosspeaks) into 320 µM 15N ARNT PAS-B. Slow exchange behavior was observed, indicated by the disappearance of apo-crosspeaks and concomitant appearance of new peaks. b. Minimum chemical shift analysis of KG-548 titration into ARNT PAS-B, mapped onto the sequence and secondary structure. c. Chemical shift mapping suggests that KG-548 binds the ARNT PAS-B cavities, as shown by a heat map of KG-548-induced chemical shift changes on the ARNT PAS-B crystal structure (Δδmcs colored from low (blue) to high (red)) with the largest changes near the internal cavities (mesh).
a. Titration of KG-548 into an in vitro pulldown assay of minimal ARNT PAS-B and TACC3-CT interacting fragments shows a dose-dependent reduction in ARNT/TACC3 complex formation. b. Quantification of KG-548 potency for disrupting the ARNT PAS-B/TACC3-CT interaction as provided by AlphaScreen, showing an apparent IC50 of 25 µM. c. Co-immunoprecipitation assays of full length ARNT and TACC3 proteins in HEK293T cell lysates show that KG-548 weakens the ARNT/TACC3 interaction as demonstrated by the dose-dependent decrease in the intensity of the ARNT protein band (quantitated with % remaining compared to DMSO control) associated with immunoprecipitated TACC3 protein.
a. KHS101 facilitates TACC3 degradation in a proteasome-dependent manner. HEK293T cells were treated with 5 µM KHS101, 100 µg/ml cycloheximide (CHX) (upper panel); additional cells were similarly treated with KHS101 and CHX plus 20 µM MG132 (lower panel). Cells were harvested 0µ8 hr post-treatment and prepared for TACC3 immunoblot analyses. b. Quantification of TACC3 protein levels from data shown in panel a. Without MG132, TACC3 protein levels decreased, with greater drops observed in KHS101-treated cells (compared to DMSO) after 6 hr incubation. A statistically-significant difference was observed 6 hr post-treatment (p < 0.01 by Student's t-test); the 8 hr timepoint also shows a substantial decrease in TACC3 levels, but this is not statistically significant due to large variations in data values. In the presence of MG132, we observed little decrease in TACC3 levels with no KHS101-dependent effects, implicating a proteasomal-dependent degradation pathway. c. Steady state treatment with KHS101 reduces TACC3 levels. HEK293T cells were treated with KHS101 (0 – 15 µM) and immunostained with TACC3 AB1 after 14 hr. TACC3 intensity was negatively affected by KHS101. d. KHS101 induces cell differentiation with a minimum of 6 hr exposure. Adult rat NPCs were exposed to 5 µM KHS101 (or DMSO) for the indicated times, after which media were replaced with compound-free versions and incubated for a total of 100 hr. Neuronal differentiation was assessed by expression of the TuJ1 marker, showing upregulation after times consistent with TACC3 levels falling in CHX-treated cells (panels a, b).
a. KHS101 treatment potently reduces HIF target gene expression. Hep3B cells were treated with KHS101 (0–25 µM) and incubated under hypoxia (1% O2) for 16 hr. The expression of three HIF-driven genes (EPO, PGK1, GLUT1) were assessed by qPCR, demonstrating KHS101 inhibiting transcription with IC50 < 5 µM. b. HIF-1α mRNA level was measured by qPCR, showing no significant change with increasing KHS101 concentration. c. HIF-1α protein levels are reduced in a KHS101 dose-dependent manner, using anti HIF-1α Western blot.


text:
Radiation by Fiona Rae
22:28 Sep 6, 2004
Glassy-eyed as usual
A couple of wisdom teeth were forcibly removed from my upper jaw a couple of weeks back, which meant lying glassy-eyed on the couch in a drug-induced haze starring at a flickering screen. Not much different from usual then. If the Nurofen/Panadol combo didn't work, then the Olympics coverage did the trick. Apart from the Kiwis, it got reasonably boring towards the end. You know it's time to go to bed when you're watching the sixth and seventh place games for handball.
But now that normal service has been resumed on the goggle box, it's back to enjoying quality American programming, although it's too early to make a judgment on Six Feet Under. It was certainly a very sombre start, but I must confess to enjoying Las Vegas, which is a perfect Friday night, don't-bother-thinking, we'll-do-the-explaining-for-you kind of show. It's got those whizzy moments a la CSI, and James Caan, despite being shorter than the eye candy lead guy, has presence.
In fact, Las Vegas was named a guilty pleasure in a recent Entertainment Weekly – or, rather, Nikki Cox's boobs were named the guilty pleasure. It's true. Never in history have so many bosoms been on display for the commercial gain of so few. Boob jobs must be practically written into hopeful starlet's contracts these days, although I suppose half the viewing audience isn't complaining. Still, I'd rather have boobs than Bush. No, wait, that didn't come out right.
Interesting little tiff that's been reported about the NZ On Air money that went into NZ Idol. I was under the mistaken impression that NZ On Air had got its money back, simply because NZ Idol was so successful. I mean, if that didn't make money, what does? I do think it was a legitimate programme to fund, though; thousands of people watched it, it's spawned a genuine pop idol of our own with the possibility of going further, and it's given Paul Ellis something to do.
It's also very easy to say with the benefit of hindsight that it shouldn't have been funded; but before it went to air, no-one knew how well it would do. After the True Bliss experience, success wasn't a given, although the New Zealand music industry is a much changed beast since then. Speaking of that, did anyone see Cameron Bennett's story. On. Sunday. About. The. Datsuns? Could he have overemphasised every word more? I think not. Quite rightly, Christian Datsun told him where to go as well when it came to questions about the money and their mums. Fair enough.
The Fall season is nearly upon US screens. Zap2it's TV Gal gives a rundown here.
Marton Csokas and Karl Urban may be doing well in The Bourne Supremacy, but our other big local star, Beautiful Scenery, gets a good review in Without a Paddle, the Seth Green/Burt Reynolds movie that shot here recently (boy they pumped that out quick). Warning: even trailers come with ads nowadays. If you watch the trailer, there's an ad first for Guess Who's Coming to Decorate.
Here's something interesting from Lindsay Vette, who find that when he tried to record overnight on Sky Digital, he got spam:
I found I had for the second time fallen victim to Sky's version of spam when wanting to record cycling. The first time was during the Tour de France. What is with Sky and my cycling?
Sky's spam consists of remotely switching your channel at midnight to the mosaic, with an advertising banner for some new and expensive service in the main window. That was what I recorded three hours of last night.
The first time this happened I complained to Sky only to be told it must have been a power surge that caused my decoder to reset to the mosaic. But no, an experiment shows that the decoder doesn't power back on at all after an outage.
IT'S SPAM!! And I am paying for it. I await their response to my latest complaint.
I didn't know that. I did know that if you mute on Sky Digital and then record something, it gets recorded without sound. Yes. And when that something is Buffy, well. You might be forced to say a rude word.
August 1 Views: Artefacts, art and Grand Designs
July 25 Views: Punk, People and Stars
July 18 Views: Pasifika comedy, London drama, Aussie kids
Radiation Archive
About Fiona Rae
@FionaRae


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• Facebook is being accused of censoring Palestinian activists who protest the Israeli occupation. This comes as Israeli Justice Minister Ayelet Shaked reportedly said in December that Tel Aviv had submitted 158 requests to Facebook over the previous four months asking it to remove content it deemed "incitement," and said Facebook had granted 95 percent of the requests.
JUAN GONZÁLEZ: Well, we're spending the hour with Glenn Greenwald. His new report for The Intercept is about Facebook censorship. It's titled "Facebook Says It Is Deleting Accounts at the Direction of the U.S. and Israeli Governments." In it, he writes that Facebook representatives met with the Israeli government to determine which Facebook accounts of Palestinians should be deleted on the grounds that they constituted, quote, "incitement." Alternatively, Israelis have virtually free rein to post whatever they want about Palestinians, and calls by Israelis for the killing of Palestinians are commonplace on Facebook and largely remain undisturbed. That includes a recent Facebook campaign calling for vengeance against Arabs in retribution for the killing of three Israeli teenagers.
AMY GOODMAN: All of this follows President Trump's recognition of Jerusalem as Israel's capital and as the Israeli right-wing's push now to doom any attempt at a two-state solution. Today's New York Times reports, quote, "Prime Minister Benjamin Netanyahu's party for the first time has urged the annexation of Jewish settlements in the West Bank, and the nation's top legal officers pressed to extend Israeli law into occupied territory. In addition, the Israeli Parliament, after a late-night debate, voted early Tuesday to enact stiff new obstacles to any potential land-for-peace deal involving Jerusalem." Again, that's in The New York Times today.
Well, for more, we continue our conversation with Glenn Greenwald, the Pulitzer Prize-winning journalist and founding editor of The Intercept. So, your piece is headlined "Facebook Says It Is Deleting Accounts at the Direction of the U.S. and Israeli Governments." Can you explain exactly which accounts are being deleted and how you found this out?
Now, this rationale is sort of dubious. There are other people who are on the same list, like the president of Venezuela, Nicolás Maduro, and many of his top officials, who continue to use Facebook quite actively. But what the rationale actually means, if you think about it, is that the U.S. government, according to Facebook, now has the power to dictate to Facebook who it is who's allowed to use that platform to communicate with the world, and who will be blocked and who will be banned. And, you know, you can take the position, on the one hand, that Facebook is a private company, and it has the right to determine who uses its platform, which is true. The First Amendment technically doesn't apply to Facebook. But Silicon Valley giants have become so powerful and massive—I would say, in particular, Google, Facebook and Apple—that they're really much more akin now to public utilities, to almost their own private nation-states, than they are to just average corporations that have competition and the like, so that the power to eliminate somebody from Facebook is almost the power to eliminate them from the internet.
And to hear Facebook say it's the U.S. government, the Trump administration, that has the power to tell us who will use Facebook and who can't is extremely chilling, especially since already last year they proved that they were willing to do the same thing when it came to the Israeli government. As you just mentioned, Amy, there's an article in The New York Times today detailing that the Israeli right, which basically is the dominant faction in Israel, is finally being open about the fact that their real goal is not a two-state solution or a peace process, but is the annexation of the West Bank. And these politicians who are now openly advocating this are the same ones who summoned Facebook executives in October of last year to a meeting and directed them to delete the accounts of a huge number of Palestinian activists, journalists, commentators. And Facebook obeyed in almost every one of the cases, even though, as you indicated, Israelis remain free to say the most heinous and awful things about Palestinians, including an incitement.
So you see Facebook now collaborating with the most powerful governments on the planet—the Israelis and the Americans, in particular—to determine who is allowed to speak and who isn't and what messages are allowed to be conveyed and which ones aren't. And it's hard to think of anything more threatening or menacing to internet freedom and the promise of what the internet was supposed to be than behavior like this.
"Just last week, Twitter promulgated a new policy, in response to exactly the kind of demands, Amy, that you were just describing. And this is their policy. They said you are no longer allowed to use Twitter to advocate or incite violence, except if you want the violence to be done by governments or military. (JO's emphasis).
How, in a society that is allegedly a democracy, has it become possible for corporations to grow so fast, to do so systematically what they do and then obey and align themselves with government violence and quell the oppressed, the underdogs, the dissidents?
And how has it all happened with so little public debate?
One Response to "Is Facebook Operating as an Arm of the Israeli State and the US?"


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One of the main reasons why so many choose to use our Asia cruises departing Australia is the fact that it allows such easy access to the experience overall. You will get to engage and talk with a lot of people from various cultures, and you will get to experience some truly profound living experiences.
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Learn More About Parking Regulations and How They Affect You
City building | May 20, 2021
Mississauga is made up of different neighbourhoods. How people live, work, play and move can vary across these neighbourhoods. So it follows that parking requirements for new construction and new businesses should not be one-size-fits-all. Demographics and preferences have also changed over the years, as has the demand for private parking.
Parking plays an important role in city building. It can shape how buildings are designed, how residents move and the way businesses evolve. The City of Mississauga is updating its off-street parking regulations under its Zoning By-law. Off-street parking refers to the amount of vehicle or bicycle parking that is required on private and public properties as a result of new development, redevelopment or a land use change. It does not apply to existing buildings, homes, street parking or municipal parking lots.
Parking is expensive to build and maintain. By updating the regulations for private parking, the City can support housing affordability, enhanced development and economic opportunities and offer more mobility options that can help lower carbon emissions.
The City has launched its Parking Regulation Study to provide an updated framework to support future parking regulations. On Monday, May 31 at 6 p.m., City staff will present a draft report to the Planning and Development Committee that provides background research, draft policy directions and proposed vehicle and bicycle off-street parking regulations.
Meeting participants will have the opportunity to ask questions and share their feedback about the proposed changes. Watch the live meeting while it's in session by viewing the livestream.
The Parking Regulations Study is a key action from the City's recently-approved Parking Master Plan and Implementing Strategy (PMPIS). It is also implementing key actions from the Transportation Demand Management (TDM) Strategy, 2018 and bicycle parking requirements in the City's Zoning By-law noted in the 2018 Cycling Master Plan.
For more information about the Parking Regulations Study, visit yoursay.mississauga.ca/parking-regulations-study, see the FAQs or contact us at parking.regs@mississauga.ca.


A total of 28 pastry schools from across the whole of Spain have registered for participation in the second National Championship for Student Pastry Chefs, organised by the Spanish Confederation of Artisan Pastry Companies (CEEAP). 26 of the entrants will participate in the competition, to be held on 25 and 26 February 2019 within the framework of Intersicop, the International Bakery, Pastry, Ice-cream and Coffee Show, organised by IFEMA at Feria de Madrid.
The CEEAP has expanded the competition following the notable success of its debut year, in which 24 schools participated and the top prize went to Paula Pons from the Pastry School of the Guild of Barcelona. The level of participation reflects the warm welcome that the pastry-making sector has given to this competition, which promotes high-quality professional education in pastry-making and offers an opportunity to promote their training provision.
One of the changes made for this second contest is the new age limit, which has risen from 22 to 24 years of age. Applicants will have eight hours to create nine pieces of filled and decorated choux pastry, two chocolate cakes with a minimum of three different components and – to replace last year's croissants – nine mille-feuille pastries with a pastry base and two layers of filling of the student's own choice.
The 26 competing schools come from Catalonia, Murcia, Asturias, Andalusia, Cantabria, Castile-La Mancha, Valencia, Madrid, Castile and León, Galicia and Mallorca.


Signs and wonders are not a gift but a promise to all believers. For over 40 years Frans has walked in the miraculous. His life is a stirring testimony to the power of God's supernatural provision, revelation, intervention, healing and, most of all, His loving, abiding and never failing presence, not only for himself and his family, but for many others as well. Contrary to the views of many, Frans insists, signs and wonders should be as normal for the church today as they were for the New Testament church in the days of the apostles. Miracles are not reserved for the super-spiritual, but should be the bread and butter of daily life for the ordinary believer. In a season for miracles, Frans proves his point through powerful vignettes drawn from his own life experiences and testimonies that will have you laughing, crying, shouting, praising, and worshiping in awestruck silence the God of miracles, mercy, and grace. Most importantly, Frans' stories will strengthen your faith, building up in you that confident conviction that you too can walk in the miraculous.
At the tender age of 16, Frans Du Plessis came to the Lord. He then entered full-time ministry in South Africa in his early 20's and has served as pastor of a local congregation since 1975. His passion is to see the Word of God fulfilled in his time and the earth filled with the glory of God. He has raised up spiritual sons and daughters all over the world who are leaders of their own spiritual children and local congregations. Frans is part of an apostolic eldership who minister in more than 50 nations of the world. Their passion is to see the Church coming to maturity and form part of the corporate son who must manifest the image and likeness of God to creation. His personal ministry to many nations of the world has always been characterized by a strong anointing of the Holy Spirit. He functions apostolically with a solid prophetic edge, and his message carries a firm element of revelation. Since 1975, Frans has been happily married to Netta with whom he has three married children, all of whom are also involved in full-time ministry. Their five grandchildren are the joy of their lives.


"All of you eat apples"
I'm using the Diné bizaad keyboard on Gboard for my phone and it won't accept ' as correct, even though it is the mark specifically used on this keyboard for a glottal stop. Clearly there's an issue here with the beta.
Cant complete this sentence. nothing is acceptable.


This paper explores options for programs to be put in place prior to a disaster to avoid large and often poorly-managed expenditures following a catastrophe and to provide appropriate protection against the risk of those large losses which do occur.
Objective of the publication is to formulate key aspects of a regional action plan for climate adaptation. The format is an idealistic presentation - a blueprint. It contains of a first part for policy makers and a second part with further background information.
The report summarizes the results of a workshop which used the Delphi-method. The objective was to show important impacts and adaptation measures on flooding, groundwater and low-level water in Germany.
This article discusses the role insurance can play in adapting to climate change impacts. The particular focus is on the Dutch insurance sector, in view of the Netherlands being extremely vulnerable to climate change impacts.
Ein 10-Punkte Plan Klimaanpassung – Raumentwicklungsstrategien zum Klimawandel im Überblick (A 10-Point Plan Climate Adaptation - Regional development strategies for Climate Change in Overview).
The paper is focusing on climate change and consequences for regional planning.The paper has a strategic, conceptual perspective. It shows mainly the further research needs.
Thes use the DIVA tool to calculate the benefits of a normative coastal protection target versus a business as usual (BAU) scenario for the EU coastal states.


Three Spears School of Business faculty members were recognized for their outstanding performance in the classroom during the 2015 Watson Graduate School of Management Scholarship and Awards Banquet on April 19.
Those honored were Ajay Sukhdial, Outstanding MBA Faculty Award; Cynthia Wang, Greiner Graduate Excellence in Teaching Award, and Rick Wilson, Chandler Frates and Reitz Teaching Excellence Award.
Sukhdial, associate professor in the Department of Marketing, was recognized with the Outstanding MBA Faculty Award, which is given annually to the outstanding faculty member on the Stillwater campus. It is based on nominations from MBA students.
Wang, associate professor in the Department of Management, was the recipient of the Greiner Graduate Excellence in Teaching Award. Created in 1987, the Greiner Award recognizes an outstanding graduate faculty member annually through nominations by students and fellow professors.
Wilson, professor and head of the Department of Management Science and Information Systems and W. Paul Miller Professor of Business Administration, was the winner of the Chandler Frates and Reitz Teaching Excellence Award. It is presented annually to the outstanding MBA faculty teaching on the OSU-Tulsa campus. Wilson also won the Chandler Frates and Reitz award in 2010.


There's debate as to the benefits of revising in the day compared to the pros of revising at night.
Do you find it easier in the day so it's done out of the way, or do you prefer the peace and quiet of revising in the evening when most people are asleep?
We know that so many people struggle to feel awake enough in the morning to revise, which is why people will lean towards revising at night. Sleeping straight after studying is also meant to help with memory recall, so perhaps the night owls are on to something?
Do you agree? Let us know what you prefer / works best for your revision.
That's a really great point about exams being in the morning. Definitely a great idea to tailor your revision routine, so that you feel awake and ready for them. Thanks for sharing that great tip!
I think a lot of people feel the same. I always seem to get loads of creative thoughts and ideas late at night. This was really great for doing practice essays, and them looking back over them in the morning to see what new ideas had formulated.
A-level/As-level students,how many hours do you work a week?
My parents seems to be too strict.


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Micromorphological Analysis of Activity Areas at the Early Bronze Age (EBA) Village of TAV Afragola in Southern Italy
Tiziana Matarazzo, University of Connecticut - StorrsFollow
micromorphology, Bronze Age, Vesuvius, Avellino Eruption
Natalie Munro
Co-Major Advisor
Paul Goldberg
Francesco Berna
Sally McBrearty
In Europe, the Early Bronze Age (EBA) is an important transitional period characterized by emergent social complexity, the beginning of labor specialization, and arguably, an increasingly stratified social system. There is controversy surrounding the timing of these events on the Campania Plain of southern Italy however, and some scholars argue that this level of social complexity did not occur until the Middle Bronze Age. This research utilizes micromorphological analysis of thin sections of undisturbed sediment collected at the EBA village of Treno Alta Velocitá (TAV) Afragola on the Campania Plain in Southern Italy to understand how people used living spaces, organized daily activities and related to other members of the village. In particular, micromorphology is used to identify the type and range of human activities, the function of features and buildings, and the intensity of site occupation. The remarkable preservation of the village of TAV Afragola and neighboring sites on the Campania Plain is unmatched in Europe. The site was buried in nearly a meter of volcanic ash during the Avellino eruption of Vesuvius in 3,950 cal BP. The site boasts a large number of well-preserved structures, built features and organic materials and thus provides a laboratory-type setting in which to investigate variability in artifact distribution and activity areas across a single village.
Micromorphological analysis reveals a general lack of material remains embedded in the domestic occupation surfaces at Afragola. This result is surprising, given the complexity of the site as evidenced by multiple buildings utilized for storage and domestic activities. More specifically the presence of large quantities of burned seeds in one structure suggests that Afragola was an established agricultural village. One explanation for this disparity is that the village was occupied only briefly before the Avellino eruption destroyed it. No clear archaeological or micromorphological evidence for socio-economic differentiation or specialized production of materials, such as metals or pottery, has emerged from Afragola.
Each domestic structure at Afragola is equipped with a concotto, a fired-clay surface deliberately constructed for cooking, and an associated accumulation of fire ash. Both features suggest that small-scale pyrotechnological activities routinely occurred within these domestic structures. There is little evidence of variation within the activity areas of all domestic buildings, suggesting that their use was not specialized. Similar use of the habitation structures and the domestic nature of the activities that occurred there suggest a lack of social differentiation or social hierarchy. The micromorphological analysis at Afragola provides a unique example of a briefly occupied agricultural village with what appears to be minimally stratified social organization during the EBA of southern Italy.
Matarazzo, Tiziana, "Micromorphological Analysis of Activity Areas at the Early Bronze Age (EBA) Village of TAV Afragola in Southern Italy" (2014). Doctoral Dissertations. 633.


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Home/Trends/PM Modi Distributes 71,056 Appointment Letters To New Recruits Under Rozgar Mela
PM Modi Distributes 71,056 Appointment Letters To New Recruits Under Rozgar Mela
pema Send an email November 26, 2022
Prime Minister Narendra Modi on Tuesday handed out 71,056 appointment letters to newly hired candidates under the Rozgar Mela.
Prime Minister Narendra Modi on Tuesday handed out 71,056 appointment letters to newly hired candidates under the Rozgar Mela, according to a statement from the Prime Minister's Office
The new recruits received the appointment letter from the Prime Minister through a video conference and by doing so, the government is showing its commitment to provide youths government jobs.
During the event, the Prime Minister emphasised that the endeavour to give youths job opportunities will continue and will aid in nation-building while mentioning that the Mela was hosted in Jammu and Kashmir, Gujarat, the Andaman Islands, UP, and Maharashtra.
The Prime Minister, while handing out the appointment letters, said that the country's greatest asset is its youth and making use of their talents and enthusiasm for nation-building country is the government's top priority
The Prime Minister, while handing out the appointment letters, said that the country's greatest asset is its youth and maing use of their talents and enthusiasm for nation-building country is the government's top priority. The Rozgar Mela is expected to serve as a catalyst for increasing employment generation and giving the younger generation worthwhile opportunities for empowerment and direct involvement in advancement of the country.
According to PM Modi, initiatives like 'Make in India' and 'Vocal for Local' are fostering employment and chances for self-employment throughout the country.
Meanwhile, the Production Link Initiative (PLI) programme was also emphasized by Prime Minister Modi as a potential source of new employment prospects.
Prime Minister Modi further said that it is predicted to generate 60 lakh new employment possibilities through the PLI scheme alone. All of these programmes, including Make in India and Vocal for Local, are creating opportunities and self-employment prospects in the nation. This shows that there are more and more opportunities for both government and non-government jobs.
The Prime Minister underlined his commitment to making India a developed country during the Amrit Kaal and declared that the new recruits will act as the country's "saarthi" during this period
Prime Minister Modi underlined his commitment to making India a developed country during the Amrit Kaal and declared that the new recruits will act as the country's "saarthi" during this period. The Prime Minister, address the new recruits said that all of you who will take on this new duty have been designated to serve as the Central Government's representatives in front of the rest of the country and asked the new hires to work on capacity-building to push the government's efficiency.
He emphasized that to improve government efficiency, all of them should engage on capacity-building and stated that letters of appointment are distributed to around 71,000 youths in 45 cities right now. This will result in thousands of families filled with joy.
The new appointees will receive physical copies of their appointment letters at 45 locations across the country (except Himachal Pradesh and Gujarat), the Prime Minister's Office (PMO) stated. It added that posts for teachers, lecturers, nursing officers, nurses, doctors, radiographers, pharmacists and other technical and paramedical positions are now being filled in addition to the categories of positions already filled. A number of vacancies in the Central Armed Police Forces (CAPF) are being filled by the Ministry of Home Affairs.
It may be mentioned that 75,000 appointment letters were given to new appointees under Rozgar Mela earlier in October.
The Rozgar Mela, according to Prime Minister Modi, is evidence that the national government is actively working to give job opportunity to the younger generation in the country.
The Karmayogi Prarambh module, an online orientation programme for all new hires in different government departments, was also introduced by the Prime Minister
According to Prime Minister Modi, states and union territories will continue to hold Rozgar Melas. Meanwhile in Gujarat, Uttar Pradesh, Maharashtra, Daman and Diu, Jammu & Kashmir, Andaman and Nicobar, Lakshadweep, Ladakh, Dadra and Nagar Haveli, and Chandigarh, PM Modi expressed happiness that the respective governments had given appointment letters to thousands of youths.
The Karmayogi Prarambh module, an online orientation programme for all new hires in different government departments, was also introduced by the Prime Minister. The PMO stated that it would include a code of conduct for government employees, workplace ethics & integrity, human resource regulations, and other advantages and allowances that would assist them get accustomed to the rules and move into the new responsibilities without any difficulty.
According to the statement, they will also have the chance to explore other courses on the igotkarmayogi.gov.in platform to expand their knowledge, skills, and abilities.
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This means we always keep up to date with the latest training and industry developments, so we can offer the most advanced and effective treatments. We've also put together a team who can deliver every type of dentistry, from teeth straightening to dental implants and whitening, so you can receive a comprehensive service from professionals you know and trust.
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ICBNE 2015 will be started on 22 Apr and it will be end on 23 Apr 2015.
ICBNE 2015 will be held at the Arnoma Grand Bangkok Hotel in Bangkok, Thailand.
International Conference on Biotechnology, Nanotechnology and Environmental Engineering (ICBNE 2015) is going to be the inaugural event about Biotechnology, Nanotechnology and Environmental Engineering.
International Conference on Biotechnology, Nanotechnology and Environmental Engineering is organized once.


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Bryconamericus singularis är en fiskart som beskrevs av Román-valencia, Taphorn och Ruiz-c. 2008. Bryconamericus singularis ingår i släktet Bryconamericus och familjen Characidae. Inga underarter finns listade.

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