text:
Q: Using identity for the derivative of Dirac Delta function I know that you can define the derivative of the delta function as:-
$$\delta'(x)=-\frac{1}{x}\delta(x)$$
If i use this to calculate the integral with $f(x)$, I get 2 different results.
Method 1:-
$$\int_{-\infty}^{+\infty}\delta'(x)f(x)dx = -f'(0) $$ by using integration by parts.
Method 2:-
$$\int_{-\infty}^{+\infty}-\frac{1}{x}\delta(x)f(x)dx = \lim_{x\to0} -\frac{f(x)}{x}$$
I think I am doing something wrong in method 2 as the 2 results do not match.
I do not know much about distribution theory and would appreciate any help.

A: You could use the symmetry of the integrand, assuming that these integrals make sense in some weak sense.
$$
\int_{\Bbb R}\frac{f(x)}xδ(x)\,dx
=\frac12\int_{\Bbb R}\left(\frac{f(x)}x+\frac{f(-x)}{-x}\right)δ(x)\,dx
=\int_{\Bbb R}\left(\frac{f(x)-f(-x)}{2x}\right)δ(x)\,dx
$$
If $f$ is continuously differentiable, the difference quotient has a continuous continuation to $x=0$ with value $f'(0)$. Then the original definition of the Dirac delta applies to give the integral exactly this value at $x=0$.

A: If one wants to go strictly by definition, for every multi-index $\alpha$, test function $f:\mathbb R^n\to\mathbb C$ and tempered distribution $u$ one defines $(D^\alpha u)(f)=(-1)^{|\alpha|} u(D^\alpha f)$ (cf. Theorem 7.13 in Rudin's "Functional Analysis"). This definition ensures that "the usual formal rules of calculus hold" (Rudin, Ch.6.1).
Taking $u=\delta$ with $\delta(f):=f(0)$ being the delta distribution one immediatly gets
$$
\int_{-\infty}^\infty \delta'(x) f(x)\,dx\overset{(\leftarrow\text{ formally)}}=\delta'(f)= -\delta(f')\Big(\overset{\text{(formally }\rightarrow)}=- \int_{-\infty}^\infty \delta(x)f'(x)\,dx \Big)=-f'(0)\,.
$$
This is how one would obtain the derivative of the delta distribution rigorously without using the purely formal integral expression with $\delta(x)$ which, of course, is not even a function.

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text:
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India´s Cash Run Ignites Demand for Bitcoin
by Martin Lindak and F.A. Hayek Foundationon December 27, 2016 August 7, 2017
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Isokivi || Creative Commons
The past two weeks generated significance for Bitcoin mostly from the region of India. Talks about the future of the Italian banking sector were also on the agenda while interesting news kept pouring in from China, South Korea and Dubai.
As anticipated in our previous article, the trade of Bitcoin had evidenced a sharp increase in India. This is due to the government´s decision to pull the two most popular banknotes out of circulation. The executive´s intention is to "clear up" the currency as a large number of false banknotes is supposedly still in circulation. This step has seemingly boosted the cause of alternative payment mechanisms such as Bitcoin. Its price currently floats around 900 dollars on the Indian market, adding up to a value 16% higher than the global average. India can thus showcase another example of Bitcoin´s potential to serve as an alternative to national currencies that find themselves in trouble.
Hints of a similar situation possibly emerging in Italy caught the headlines around Europe. Nevertheless, the expected development pattern of this script resembles more the 2013 Cyprus situation. That year saw a tenfold multiplication in the trade of Bitcoin as a result of the turmoil in local banks and the so-called bail-in. The source currently generating concern in Italy is Monte dei Paschi di Siena, a bank that failed its stress tests in July. The bank´s main issue is its lack of equity. Officials are trying to resolve the bank´s unfavorable condition by issuing shares of a total value of 5 billion dollars. It is questionable whether this decision pays off. If it does not, we can expect more radical steps in the near future. These would most likely benefit Bitcoin, just as they did in Cyprus. It will be equally intriguing to see the outcome of the December referendum aiming to introduce several constitutional changes. By far the most important is the question of strengthening the central government by reducing the powers of local governments and the Senators. In the current constitutional setting, the Senate shares equal powers with the Chamber of Deputies. The results will reflect citizens' attitudes towards their representatives. After Trump and Brexit, nothing is unimaginable now. A surprising result for the markets would however only benefit Bitcoin.
And now back to Asia. The Chinese Central Bank planners are heading towards a more elaborate application of cryptosystems. The bank has published job vacations seeking to recruit six experts from the field of FinTech and Blockchain, otherwise known as "the ledger", a technology at the core of Bitcoin and all other cryptocurrencies. The Chinese Central Bank and the government have both previously expressed an intention to own and apply a digital currency, making it easier to keep absolute control over the system. It remains to be seen whether this plan will actually work. However, it still reveals an interesting paradox and an emerging pattern in a socialist government being interested in cryptocurrencies. On the other side of the scale we find Singapore, a country with one of the most favorable business environments in the world. Its central bank has announced a partnership with R3, a consortium of more than 60 banks researching and analysing Blockchain. The bank´s goal is to maximize the application and implementation of benefits Blockchain has to offer – namely low costs, transparency, and security. We have described these and other characteristics in more detail in a recently published study of cryptosystems, containing full analysis of these and other (crypto)questions.
South Korea has embarked on a completely opposite course by recently announcing its intention to regulate digital currencies. The Financial Services Commission decided to proceed with further regulation in the light of the increasing popularity of Bitcoin in the country. The average monthly increase of transactions is 6% higher when compared to the previous year, amounting to a total of 1.3 billion dollars of absolute transaction value since January 2015. It is vital to stress here that the regulations in question will not inhibit the use and trade of Bitcoin. They will probably equal to measures only recently introduced in Japan in the form of requirements for all currency exchanges to be licensed and to uphold consumer rights. A similar approach has also been considered by officials in Dubai. Here it shall be emphasized that such measures do not necessarily carry negative effects, as regulations of this kind might even expand the positive reputation of Bitcoin among citizens.
Translated by Edward Szekeres
This entry was posted in Economy and tagged banking, Bitcoin, China, cryptocurrencies, currency, India, Italy, news. Bookmark the permalink.
About Martin Lindak
Analyst of F.A. Hayek Foundation.
About F.A. Hayek Foundation
The F. A. Hayek Foundation Bratislava – is an independent and non-political, non-profit organization, founded in 1991, by a group of free-market oriented Slovak economists.
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When Will Bitcoin Finally Collapse? Three Potential Threats
First, a disclaimer: the reason behind this article lies with my friend´s recent decision to invest in Bitcoin (BC). Having taken a nonchalant look at the BC´s...

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Home » News » Press Releases » » Press Releases » March, 2022
King attends JAF ceremony marking Al Karamah Battle's 54th anniversary
Al Karamah—His Majesty King Abdullah, the Supreme Commander of the Jordan Armed Forces-Arab Army, on Monday attended the JAF's ceremony at the memorial site for the martyrs of Al Karamah Battle on its 54th anniversary. King Abdullah, accompanied by His Royal Highness Crown Prince Al Hussein bin Abdullah II, was received in the Jordan Valley town...
Crown Prince meets graduates of Jaguar Land Rover Apprentice Academy
His Royal Highness Crown Prince Al Hussein bin Abdullah II on Monday reiterated that technical and vocational training is one of the most important tools to enable young people to find job opportunities. During a meeting at Al Husseiniya Palace with graduates of Jaguar Land Rover Apprentice Academy's first class, Crown Prince Al Hussein stressed...
Crown Prince attends opening of National Youth Dialogue Conference
Dead Sea—His Royal Highness Crown Prince Al Hussein bin Abdullah II on Sunday attended the opening of the first National Youth Dialogue Conference, organised by the Senate's Youth Dialogue Initiative Committee. The conference, held at the Dead Sea, aims to address key issues concerning young people, and to open new dialogue channels between the...
Crown Prince inaugurates Tafileh Inclusive Care Centre
Tafileh—His Royal Highness Crown Prince Al Hussein bin Abdullah II on Wednesday inaugurated the Tafileh Inclusive Care Centre, established under royal directives to provide quality services for people with disabilities. Crown Prince Al Hussein highlighted the importance of integrating people with disabilities in various fields, underscoring the...
Crown Prince meets young activists in Tafileh
Tafileh—His Royal Highness Crown Prince Al Hussein bin Abdullah II on Wednesday stressed the importance of an investment-friendly environment in countering poverty and unemployment, urging a move towards vocational and technical education, and setting up "training for employment" programmes. At a meeting with young activists in Dana Nature Reserve...
Crown Prince attends part of tourism sector session at National Economic Workshop
His Royal Highness Crown Prince Al Hussein bin Abdullah II on Saturday attended part of the tourism sector's interactive session, held as part of the third round of the National Economic Workshop at the Royal Hashemite Court. Crown Prince Al Hussein heard from the participants on the tourism sector priorities they have identified for the next...
Crown Prince attends joint military exercise
His Royal Highness Crown Prince Al Hussein bin Abdullah II on Tuesday, attended a joint military exercise conducted by the Jordan Armed Forces-Arab Army (JAF), with the participation of security agencies, ministries, and national institutions. The exercise, held at King Abdullah II Special Operations Training Centre (KASOTC), simulating a...
Crown Prince inaugurates engineering workshops facility at Maan University College
Maan—His Royal Highness Crown Prince Al Hussein bin Abdullah II on Wednesday inaugurated the engineering workshops facility at Maan University College, affiliated with Balqa Applied University. Crown Prince Al Hussein toured the building, established upon Royal directives to train students and hone their skills, and stressed the need to strike a...


text:
Wavre (vallonska Åve, nederländska Waver) är huvudstad och kommun i den belgiska provinsen Brabant Wallon. Stadens invånare är i huvudsak franskspråkiga.

Historia
Vid slaget vid Wavre som ägde rum den 18 och 19 juni 1815 besegrade Franska styrkor retirerande  preussiska trupper. Trots att den franske befälhavaren hörde kanonerna från slaget vid Waterloo, som ägde rum bara några kilometer västerut, valde han att stanna på platsen och besegra den lilla preussiska kontingenten. Samtidigt avhjordes Napoleons öde i nederlaget vid Waterloo.

1977 slogs kommunerna Limal och Bierges samman med Wavre. 1995 delades provinsen Brabant i en fransk- och en nederlandsspråkig del. Sedan dess är Wavre provinshuvudstad för Brabant Wallon medan Leuven är huvudstad för Vlaams Brabant.

Politik
Det senaste kommunalvalet ägde rum den 8 oktober 2006. Till borgmästaren valdes Charles Michel (MR).

Kultur och sevärdheter

Historiespelet
Sedan 1954 uppförs ungefär vart femte år spelet Jeu de Jean et Alice med sång, musik, dans och balett. Initiativen kom från kyrkoherden Jean Pensis (8/2/1907–27/3/1987), som ville ha en festlig invigning av det nya klockspelet till påsken 1954. Texten är skriven av hans vän, läkaren och diktaren Auguste Brasseur-Capart (26/2/1905–10/6/1978), musiken av Auguste Du Pont Del Sart (19/6/1912–6/4/1986). Framförandet slutar med sången om Wavre (Chant de Wavre). Refrängen spelas vid varje hel timme, av klockspelet i Saint-Jean-Baptiste-kyrkan:

«Nous aimons notre bonne ville, ses habitants, ses bois, ses champs,
La vallée, où coule tranquille, la Dyle.
De cœur, nous resterons toujours vrais Wavriens, car nous le sommes
Et la ville, où tout se transforme, peut changer, mais pas nos amours.»

"Vi älskar vår vackra stad, dess invånare, dess skogar, dess fält,
dalen där lugnt Dyleån flyter.
I hjärtat förblir vi alltid sanna Wavrianare, ty vi är det
och staden då allt ändrar sig kan förändras, men inte vår kärlek."
– Auguste Brasseur-Capart: Jeu de Jean et Alice. Wavre, 1987.

Innehållet i historiespelet är följande: Wavres invånare begär mer frihet av sina herrar, Seigneur Jean och hans hustru Dame Alice. De erhåller den önskade urkunden, glädjer sig och tackar Jean och Alice. Historien har en historisk bakgrund. Den 23 april 1222 fick Wavre en Charte de franchises som war undertecknad av hertigen av Lothringen, Brabant och Limburg. Med denna urkund gav Henrik I av Brabant, greve av Leuven, Wavre samma rättigheter som Leuven. Därmed kunde staden blir en juridisk och politisk enhet och bygga ett stadshus.

Fritid
I stadens utkant ligger nöjesparken "Walibi Belgium" som ingår i kedjan Walibi. Tidigare hette parken "Six Flags Belgium" och den ingick då i kedjan Six Flags.

Externa länkar
 Wavres webbplats

Referenser

Kommuner i Brabant Wallon

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text:
Seventy Years of Railway Photography (Hardback)
Seven Decades Behind the Lens
Transport Photographic Books Trains and Railways
By Colin Boocock
Imprint: Pen & Sword Transport
Published: 26th March 2018
You'll be £30.00 closer to your next £10.00 credit when you purchase Seventy Years of Railway Photography. What's this?
Other formats available - Buy the Hardback and get the eBook for £1.99!
Seventy Years of Railway Photography ePub (52.1 MB) Add to Basket £12.00
Seventy Years of Railway Photography Kindle (106.8 MB) Add to Basket £12.00
Colin Boococks' railway photographs are already familiar as they have been featured in a variety of railway books and magazines. This book shows around 300 of his favourite images that illustrate the many different aspects of railway photography.
The key seven chapters in this book each cover one decade from the 1940s up to the present day. Not only do they display the early improvement in his photography as he gained experience, they also bring into focus how much railways have changed over the last seventy years. Grimy steam locomotives in smoky surroundings persisted in ever-reducing pockets as more modern forms of traction spread across our railways. Working steam finally disappeared from UK main lines in 1968 and around coal mines in the mid-1980s.
The later chapters benefit greatly from Colins' world-wide travels, in which he searched for more unfamiliar railways. The growth of heritage railways also features.
Useful appendices add insights into Colins' experience of camera technologies and photographic techniques. These emphasise the changes that have faced him as his photography has moved from black-and-white to colour, and from films and darkrooms to the computer and the digital age. Colin last used film in early 2004, having embraced digital photography with enthusiasm.
One of the best known present day photographers. Colin Boocock, has written about his life and photography.
Roger Backhouse, Society of Model & Experimental Engineers
As featured by
Rail, 5th December 2018
Colin brings together some of his favourite images and writes knowledgeably about traction, as well as offering pertinent tips on taking pix.
ASLEF Journal Dec 2018
Essentially this album is about the lifetime of the author and his love of both railways and photography, covering the last 70 years, this passion continuing unabated today. Featuring over 300 monochrome and colour pictures from his worldwide travels, each with a detailed and informative caption, some with relevant photographic data.
Railway Correspondence and Travel Society
Because it provides a unique photographic record of the period 1947-2017, there is no doubt that this volume will appeal to readers with an interest in the railways of Great Britain over that time. In many instances, the images capture now-departed aspects of British culture, and as a result, Social Historians might also find the volume useful as a research tool. Photographers and railway modellers are likely to find the images and articles relating to their interests useful, with the qualified assumption (due to the lack of an Index) that they can actually locate such material. Non -'railway enthusiast' readers looking for pictures of 'pretty trains' might also find it worthy of their attention. In summary: An excellent, well written and very informative volume; a shame about the Index and Maps…
NZ Crown Mines
About Colin Boocock
Colin Boocock is a life-long railway enthusiast and an experienced railway engineer. Brought up near the green electric multiple units that passed over the level crossing at Addlestone in Surrey, he was enthralled when his parents took him to watch steam expresses at nearby Weybridge. His love for steam traction extended to modern forms as the railways developed and modernised. The sight of the then-Canon Eric Treacys booklet My Best Railway Photographs gave Colin the idea that he, too, could take photographs of trains. Seventy years on, he is still doing this. He often wonders: is this a record?
More titles by Colin Boocock
Saving £3.00 (10%)
Other titles in Pen & Sword Transport...


An unidentified woman set the statue of Virgin Mary ablaze at a Catholic church in Enugu state this morning.
The incident, many has described as shocking happened at St. Jacobs Parish Orba, Nsukka.
The suspect was immediately arrested and she is currently being interrogated to find out the reason for her action.


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PathBank
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Showing 31 - 40 of 111424 pathways
PathBank ID
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Glycerol Metabolism II
Glycerol metabolism starts with glycerol is introduced into the cytoplasm through a glycerol channel GlpF Glycerol is then phosphorylated through an ATP mediated glycerol kinase resulting in a Glycerol 3-phosphate. This compound can also be obtained through sn-glycero-3-phosphocholine reacting with water through a glycerophosphoryl diester phosphodiesterase producing a benzyl alcohol, a hydrogen ion and a glycerol 3-phosphate or the campound can be introduced into the cytoplasm through a glycerol-3-phosphate:phosphate antiporter. Glycerol 3-phosphate is then metabolized into a dihydroxyacetone phosphate in both aerobic or anaerobic conditions. In anaerobic conditions the metabolism is done through the reaction of glycerol 3-phosphate with a menaquinone mediated by a glycerol-3-phosphate dehydrogenase protein complex. In aerobic conditions, the metabolism is done through the reaction of glycerol 3-phosphate with ubiquinone mediated by a glycerol-3-phosphate dehydrogenase [NAD(P]+]. Dihydroxyacetone phosphate is then introduced into the fructose metabolism by turning a dihydroxyacetone into an isomer through a triosephosphate isomerase resulting in a D-glyceraldehyde 3-phosphate which in turn reacts with a phosphate through a NAD dependent Glyceraldehyde 3-phosphate dehydrogenase resulting in a glyceric acid 1,3-biphosphate. This compound is desphosphorylated by a phosphoglycerate kinase resulting in a 3-phosphoglyceric acid.This compound in turn can either react with a 2,3-bisphosphoglycerate-independent phosphoglycerate mutase or a 2,3-bisphosphoglycerate-independent phosphoglycerate mutase resulting in a 2-phospho-D-glyceric acid. This compound interacts with an enolase resulting in a phosphoenolpyruvic acid and water. Phosphoenolpyruvic acid can react either through a AMP driven phosphoenoylpyruvate synthase or a ADP driven pyruvate kinase protein complex resulting in a pyruvic acid. Pyruvic acid reacts with CoA through a NAD driven pyruvate dehydrogenase complex resulting in a carbon dioxide and a Acetyl-CoA which gets incorporated into the TCA cycle pathway.
BioPAX SVG SBGN SBML PWML All files (.zip)
2-Phospho-D-glyceric acid
3-Phosphoglyceric acid
Acetyl-CoA
Adenosine diphosphate
Adenosine monophosphate
D-Glyceraldehyde 3-phosphate
Dihydroxyacetone phosphate
Fructose 1,6-bisphosphate
Fructose 6-phosphate
Glyceric acid 1,3-biphosphate
Glycerol 3-phosphate
Hydrogen Ion
Menaquinol 8
menaquinone-8
Phosphoenolpyruvic acid
Pyruvic acid
sn-glycero-3-phosphocholine
Ubiquinol-1
Ubiquinone-1
β-D-Glucose 6-phosphate
( show all show less )
2,3-bisphosphoglycerate-depend...
2,3-bisphosphoglycerate-indepe...
6-phosphofructokinase I
6-phosphofructokinase II
Anaerobic glycerol-3-phosphate...
Fructose-1,6-bisphosphatase cl...
Fructose-bisphosphate aldolase...
Glucose-specific phosphotransf...
Glyceraldehyde-3-phosphate deh...
Glycerol kinase
Glycerol uptake facilitator pr...
Glycerol-3-phosphate dehydroge...
Glycerol-3-phosphate transport...
Glycerophosphoryl diester phos...
Phosphatase ybhA
Phosphocarrier protein HPr
Phosphoenolpyruvate synthase
Phosphoglycerate kinase
PTS system glucose-specific EI...
Pyruvate kinase I
Pyruvate kinase II
Uncharacterized protein yggF
Secondary Metabolites: Cysteine Biosynthesis from Serine
The pathway starts with a 3-phosphoglyceric acid interacting with an NAD driven D-3-phosphoglycerate dehydrogenase / α-ketoglutarate reductase resulting in an NADH, a hydrogen ion and a phosphohydroxypyruvic acid. This compound then interacts with an L-glutamic acid through a 3-phosphoserine aminotransferase / phosphohydroxythreonine aminotransferase resulting in a oxoglutaric acid and a DL-D-phosphoserine. The latter compound then interacts with a water molecule through a phosphoserine phosphatase resulting in a phosphate and an L-serine. The L-serine interacts with an acetyl-coa through a serine acetyltransferase resulting in a release of a Coenzyme A and a O-Acetylserine. The O-acetylserine then interacts with a hydrogen sulfide through a O-acetylserine sulfhydrylase A resulting in an acetic acid, a hydrogen ion and an L-cysteine
2-Aminomalonate semialdehyde
DL-O-Phosphoserine
L-Glutamic acid
L-Serine
NADPH
O-Acetylserine
Oxoglutaric acid
Phosphohydroxypyruvic acid
Cysteine synthase A
Cysteine synthase B
D-3-phosphoglycerate dehydroge...
NADP-dependent L-serine/L-allo...
Phosphoserine aminotransferase
Phosphoserine phosphatase
Serine acetyltransferase
Purine Nucleotides De Novo Biosynthesis
The biosynthesis of purine nucleotides is a complex process that begins with a phosphoribosyl pyrophosphate. This compound interacts with water and L-glutamine through a amidophosphoribosyl transferase resulting in a pyrophosphate, L-glutamic acid and a 5-phosphoribosylamine. The latter compound proceeds to interact with a glycine through an ATP driven phosphoribosylamine-glycine ligase resulting in the addition of glycine to the compound. This reaction releases an ADP, a phosphate, a hydrogen ion and a N1-(5-phospho-β-D-ribosyl)glycinamide. The latter compound interacts with formic acid, through an ATP driven phosphoribosylglycinamide formyltransferase 2 resulting in a phosphate, an ADP, a hydrogen ion and a 5-phosphoribosyl-N-formylglycinamide. The latter compound interacts with L-glutamine, and water through an ATP-driven phosphoribosylformylglycinamide synthetase resulting in a release of a phosphate, an ADP, a hydrogen ion, a L-glutamic acid and a 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine. The latter compound interacts with an ATP driven phosphoribosylformylglycinamide cyclo-ligase resulting in a release of ADP, a phosphate, a hydrogen ion and a 5-aminoimidazole ribonucleotide. The latter compound interacts with a hydrogen carbonate through an ATP driven N5-carboxyaminoimidazole ribonucleotide synthetase resulting in a release of a phosphate, an ADP, a hydrogen ion and a N5-carboxyaminoimidazole ribonucleotide.The latter compound then interacts with a N5-carboxyaminoimidazole ribonucleotide mutase resulting in a 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. This compound interacts with an L-aspartic acid through an ATP driven phosphoribosylaminoimidazole-succinocarboxamide synthase resulting in a phosphate, an ADP, a hydrogen ion and a SAICAR. SAICAR interacts with an adenylosuccinate lyase resulting in a fumaric acid and an AICAR. AICAR interacts with a formyltetrahydrofolate through a AICAR transformylase / IMP cyclohydrolase resulting in a release of a tetrahydropterol mono-l-glutamate and a FAICAR. The latter compound, FAICAR, interacts in a reversible reaction through a AICAR transformylase / IMP cyclohydrolase resulting in a release of water and Inosinic acid. Inosinic acid can be metabolized to produce dGTP and dATP three different methods each. dGTP: Inosinic acid, water and NAD are processed by IMP dehydrogenase resulting in a release of NADH, a hydrogen ion and Xanthylic acid. Xanthylic acid interacts with L-glutamine, and water through an ATP driven GMP synthetase resulting in pyrophosphate, AMP, L-glutamic acid, a hydrogen ion and Guanosine monophosphate. The latter compound is the phosphorylated by reacting with an ATP driven guanylate kinase resulting in a release of ADP and a Gaunosine diphosphate. Guanosine diphosphate can be metabolized in three different ways: 1.-Guanosine diphosphate is phosphorylated by an ATP-driven nucleoside diphosphate kinase resulting in an ADP and a Guanosine triphosphate. This compound interacts with a reduced flavodoxin protein through a ribonucleoside-triphosphate reductase resulting in a oxidized flavodoxin a water moleculer and a dGTP 2.-Guanosine diphosphate interacts with a reduced NrdH glutaredoxin-like proteins through a ribonucleoside-diphosphate reductase 2 resulting in the release of an oxidized NrdH glutaredoxin-like protein, a water molecule and a dGDP. The dGDP is then phosphorylated by interacting with an ATP-driven nucleoside diphosphate kinase resulting in an ADP and dGTP. 3.-Guanosine diphosphate interacts with a reduced thioredoxin ribonucleoside diphosphate reductase 1 resulting in a release of a water molecule, an oxidized thioredoxin and a dGDP. The dGDP is then phosphorylated by interacting with an ATP-driven nucleoside diphosphate kinase resulting in an ADP and dGTP. dATP: Inosinic acid interacts with L-aspartic acid through an GTP driven adenylosuccinate synthase results in the release of GDP, a hydrogen ion, a phosphate and N(6)-(1,2-dicarboxyethyl)AMP. The latter compound is then cleaved by a adenylosuccinate lyase resulting in a fumaric acid and an Adenosine monophosphate. This compound is then phosphorylated by an adenylate kinase resulting in the release of ATP and an adenosine diphosphate. Adenosine diphosphate can be metabolized in three different ways: 1.-Adenosine diphosphate is involved in a reversible reaction by interacting with a hydrogen ion and a phosphate through a ATP synthase / thiamin triphosphate synthase resulting in a hydrogen ion, a water molecule and an Adenosine triphosphate. The adenosine triphosphate interacts with a reduced flavodoxin through a ribonucleoside-triphosphate reductase resulting in an oxidized flavodoxin, a water molecule and a dATP 2.- Adenosine diphosphate interacts with an reduced thioredoxin through a ribonucleoside diphosphate reductase 1 resulting in a release of a water molecule, a oxidized thioredoxin and a dADP. The dADP is then phosphorylated by a nucleoside diphosphate kinase resulting in the release of ADP and a dATP 3.- Adenosine diphosphate interacts with an reduced NrdH glutaredoxin-like protein through a ribonucleoside diphosphate reductase 2 resulting in a release of a water molecule, a oxidized glutaredoxin-like protein and a dADP. The dADP is then phosphorylated by a nucleoside diphosphate kinase resulting in the release of ADP and a dATP
1-Methylhistidine
10-Formyltetrahydrofolate
2-(Formamido)-N1-(5-phospho-D-...
4Fe-4S
5'-Phosphoribosyl-N-formylglyc...
5-amino-1-(5-phospho-D-ribosyl...
5-Aminoimidazole ribonucleotid...
5-Phosphoribosylamine
Adenosylcobalamin
AICAR
Cobalamin
dADP
dGDP
dGTP
FAICAR
Fumaric acid
Guanosine diphosphate
Guanosine monophosphate
Guanosine triphosphate
Hydrogen carbonate
Inosinic acid
Itaconyl-CoA
N(6)-(1,2-dicarboxyethyl)AMP
N1-(5-phospho-β-D-ribosyl)glyc...
N5-Carboxyaminoimidazole ribon...
Phosphoribosyl pyrophosphate
Pyrophosphate
SAICAR
tetrahydropteroyl mono-L-gluta...
Thymidine 5'-triphosphate
Triphosphate
Xanthylic acid
Zinc (II) ion
Adenylate kinase
Adenylosuccinate lyase
Adenylosuccinate synthetase
Anaerobic ribonucleoside-triph...
ATP synthase epsilon chain
ATP synthase gamma chain
ATP synthase subunit a
ATP synthase subunit alpha
ATP synthase subunit b
ATP synthase subunit beta
ATP synthase subunit c
ATP synthase subunit delta
Bifunctional purine biosynthes...
Cob(I)yrinic acid a,c-diamide ...
GMP synthase [glutamine-hydrol...
Guanylate kinase
Inosine-5'-monophosphate dehyd...
Nucleoside diphosphate kinase
Phosphoribosylamine--glycine l...
Phosphoribosylaminoimidazole c...
Phosphoribosylaminoimidazole-s...
Phosphoribosylformylglycinamid...
Phosphoribosylglycinamide form...
Ribonucleoside-diphosphate red...
tRNA Charging
This pathway is a compilation of Escherichia coli tRNA charging reactions involving amino acids transported into the cell. The aminoacyl-tRNA synthetase is an enzyme that attaches the appropriate amino acid onto its tRNA by catalyzing the esterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA, which plays an important role in RNA translation. 20 different Aminoacyl-tRNA synthetases can make 20 different types of aa-tRNA for each amino acid according to the genetic code. This process is called "charging" or "loading" the tRNA with amino acid. Ribosome can transfer the amino acid from tRNA to a growing peptide after the tRNA is charged.
L-Alanine
L-Asparagine
L-Histidine
L-Phenylalanine
L-Threonine
ABC transporter arginine-bindi...
Alanyl-tRNA synthetase
Arginine ABC transporter perme...
Arginine transport ATP-binding...
Arginyl-tRNA synthetase
Aromatic amino acid transport ...
Asparaginyl-tRNA synthetase
Aspartyl-tRNA synthetase
Cysteinyl-tRNA synthetase
D-methionine transport system ...
D-methionine-binding lipoprote...
D-serine/D-alanine/glycine tra...
Glutamate/aspartate periplasmi...
Glutamate/aspartate transport ...
Glutamine transport ATP-bindin...
Glutamine transport system per...
Glutamine-binding periplasmic ...
Glutaminyl-tRNA synthetase
Glutamyl-tRNA synthetase
Glycine betaine-binding peripl...
Glycine betaine/L-proline tran...
Glycyl-tRNA synthetase alpha s...
Glycyl-tRNA synthetase beta su...
High-affinity branched-chain a...
Histidine transport ATP-bindin...
Histidine transport system per...
Histidine-binding periplasmic ...
Histidyl-tRNA synthetase
Isoleucyl-tRNA synthetase
L-asparagine permease
Leu/Ile/Val-binding protein
Leucyl-tRNA synthetase
Lysine-arginine-ornithine-bind...
Lysyl-tRNA synthetase, heat in...
Methionine import ATP-binding ...
Methionyl-tRNA synthetase
Phenylalanyl-tRNA synthetase a...
Phenylalanyl-tRNA synthetase b...
Prolyl-tRNA synthetase
Seryl-tRNA synthetase
Threonine/serine transporter t...
Tryptophanyl-tRNA synthetase
Tyrosyl-tRNA synthetase
Valyl-tRNA synthetase
Galactose Metabolism
Galactose can be synthesized through two pathways: melibiose degradation involving an alpha galactosidase and lactose degradation involving a beta galactosidase. Melibiose is first transported inside the cell through the melibiose:Li+/Na+/H+ symporter. Once inside the cell, melibiose is degraded through alpha galactosidase into an alpha-D-galactose and a beta-D-glucose. The beta-D-glucose is phosphorylated by a glucokinase to produce a beta-D-glucose-6-phosphate which can spontaneously be turned into a alpha D glucose 6 phosphate. This alpha D-glucose-6-phosphate is metabolized into a glucose -1-phosphate through a phosphoglucomutase-1. The glucose -1-phosphate is transformed into a uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine diphosphate glucose, can undergo a reversible reaction in which it can be turned into uridine diphosphategalactose through an UDP-glucose 4-epimerase. Galactose can also be produced by lactose degradation involving a lactose permease to uptake lactose from the environment and a beta-galactosidase to turn lactose into Beta-D-galactose. Beta-D-galactose can also be uptaken from the environment through a galactose proton symporter. Galactose is degraded through the following process: Beta-D-galactose is introduced into the cytoplasm through a galactose proton symporter, or it can be synthesized from an alpha lactose that is introduced into the cytoplasm through a lactose permease. Alpha lactose interacts with water through a beta-galactosidase resulting in a beta-D-glucose and beta-D-galactose. Beta-D-galactose is isomerized into D-galactose. D-Galactose undergoes phosphorylation through a galactokinase, hence producing galactose 1 phosphate. On the other side of the pathway, a gluose-1-phosphate (product of the interaction of alpha-D-glucose 6-phosphate with a phosphoglucomutase resulting in a alpha-D-glucose-1-phosphate, an isomer of Glucose 1-phosphate, or an isomer of Beta-D-glucose 1-phosphate) interacts with UTP and a hydrogen ion in order to produce a uridine diphosphate glucose. This is followed by the interaction of galactose-1-phosphate with an established amount of uridine diphosphate glucose through a galactose-1-phosphate uridylyltransferase, which in turn output a glucose-1-phosphate and a uridine diphosphate galactose. The glucose -1-phosphate is transformed into a uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine diphosphate glucose, can undergo a reversible reaction in which it can be turned into uridine diphosphategalactose through an UDP-glucose 4-epimerase, and so the cycle can keep going as long as more lactose or galactose is imported into the cell
D-Galactose
Galactose 1-phosphate
Melibiose
Uridine diphosphate glucose
Uridine diphosphategalactose
Uridine triphosphate
α-D-Glucose
α-D-glucose-1-phosphate
α-Lactose
β-D-Galactose
β-D-Glucose
Aldose 1-epimerase
Alpha-galactosidase
Galactokinase
Galactose-1-phosphate uridylyl...
Galactose-proton symporter
Lactose permease
Melibiose carrier protein
Phosphoglucomutase-1
putative aldose 1-epimerase
Putative beta-phosphoglucomuta...
UDP-glucose 4-epimerase
UTP--glucose-1-phosphate uridy...
Methionine Biosynthesis
This pathway shows the biosynthesis of methionine, which is an energy-costly process. Lysine biosynthesis produces L-Aspartate-semialdehyde, which later on is catalyzed to L-homoserine by bifunctional aspartokinase (also named homoserine dehydrogenase) 1 and 2. Homoserine is then activated by O-succinylation to form O-succinyl-L-homoserine via homoserine O-succinyltransferase (metA). Combining with L-cysteine, O-succinyl-L-homoserine form L-cystathionine and succinic acid by cystathionine gamma-synthase (metB). Cleavage of L-cystathionine by cystathionine beta-lyase (metC) or Protein MalY(as ) generates two small molecules: homocysteine and 2-aminoprop-2-enoate. Methionine synthase(MetH) or 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase(MetE) will catalyzehomocysteine to form the final product: methionine. In E.coli, MetH can only function with existence of cobalamin (Vitamin B12), which can be available in the guy; without cobalamin, MetE will not be repressed so that it will catalyze the methionine. Methionine can be transported out of cell (into periplasmic space) by leucine efflux transporter.
N5-methyl--tetrahydropteroyl ...
2-aminoprop-2-enoate
L-Aspartate-semialdehyde
L-Cystathionine
N5-methyl--tetrahydropteroyl t...
O-succinyl-L-homoserine
S-Methylmethionine
Succinyl-CoA
Tetrahydropteroyltri-L-glutama...
5-methyltetrahydropteroyltrigl...
Bifunctional aspartokinase/hom...
Cystathionine beta-lyase metC
Cystathionine gamma-synthase
Homocysteine S-methyltransfera...
Homoserine O-succinyltransfera...
Methionine synthase
Protein malY
Uncharacterized protein YbjE
Fatty Acid Elongation In Mitochondria
Cells typically contain large amounts of C18 and C20 fatty acids. Longer chain fatty acids are derived from either dietary sources or from elongation of C16-CoA or C18-CoA formed by the cytoplasmic fatty acid synthetase system. All of the fatty acids needed can be synthesized from palmitate (C16:0) except the essential polyunsaturated fatty acids such as linoleate and linolenate. To create longer, shorter, oxidized, reduced fatty acids, palmitic acid is subjected to enzymatic reactions by reductases, hydroxylases, elongases and mixed function oxidases. There are 3 major processes that modify palmitic acid: elongation, desaturation, and hydroxylation. Elongation of fatty acids may occur at endoplasmic reticulum where fatty acid molecules of length up to C24 may be produced. Mitochondrial elongation may result in fatty acids up to C16 in length. Fatty acid elongation in mitochondria is essentially the reverse of beta-oxidation for fatty acid oxidation. In particular, both pathways make use of acetyl-CoA acyltransferase, 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase. The final step of fatty acid elongation uses enoyl-CoA reductase (not part of the beta-oxidation pathway). The mitochondrial pathway is important for elongating fatty acids containing 14 or fewer carbon atoms. Fatty acids with aliphatic tails of less than six carbons are short-chain fatty acids (SCFA). Medium chains (MCFA) have a six to twelve carbon tail and large chains (LCFA) have a tail with greater than twelve carbons. Very long chain fatty acids (VLCFA) have a tail with greater than twenty-two carbons.
(2E)-Decenoyl-CoA
(2E)-Dodecenoyl-CoA
(2E)-Hexadecenoyl-CoA
(2E)-Hexenoyl-CoA
(2E)-Octenoyl-CoA
(2E)-Tetradecenoyl-CoA
3-Hydroxydecanoyl-CoA
3-Hydroxydodecanoyl-CoA
3-Hydroxyhexadecanoyl-CoA
3-Hydroxyhexanoyl-CoA
3-hydroxyoctanoyl-CoA
3-Hydroxytetradecanoyl-CoA
3-oxodecanoyl-CoA
3-oxododecanoyl-CoA
3-oxohexadecanoyl-CoA
3-oxohexanoyl-CoA
3-oxooctanoyl-CoA
3-oxotetradecanoyl-CoA
Butyryl-CoA
Decanoyl-CoA
Hexanoyl-CoA
Lauroyl-CoA
Octanoyl-CoA
Palmitic acid
Palmitoyl-CoA
Tetradecanoyl-CoA
3-ketoacyl-CoA thiolase, perox...
Glycerophospholipid Metabolism
The metabolism of glycerophospholipid begins with glycerone phosphate either reacting with glycerol-3-phosphate dehydrogenase resulting in the release of glycerol-3-phosphate or it can react with glycerol-3-phosphate O-acyltransferase / dihydroxyacetone phosphate acyltransferase resulting in the release of a 1-acylglycerone 3-phosphate. Glycerol-3-phosphate reacts with glycerol-3-phosphate O-acyltransferase resulting in the release of an acyl glycerol phosphate. 1-acylglycerone 3-phosphate 1-acyl dihydroxyacetone phosphate reductase resulting in the release of a acyl glycerol phosphate. The latter compound then reacts with a oleoyl-CoA: lysophosphatidate acyltransferase resulting in the release of a phosphatidic acid. The latter compound reacts with Phosphatidic acid phosphohydrolase 1 resulting in the release of diacyl glycerol. This compound can be metabolized through a CTP-dependent diacylglycerol kinase 1 resulting in the release of a phosphatidic acid. Diacyl glycerol reacts with cdp-ethanolamine through a bifunctional diacylglycerol cholinephosphotransferase/ethanolaminephosphotransferase resulting in the release of a phosphatidyl ethanolamine.
1-palmitoylglycerone 3-phospha...
CDP-ethanolamine
Cytidine monophosphate
Cytidine triphosphate
DG(16:0/16:0/0:0)
Ethanolamine
Glycerone phosphate
LysoPA(16:0/0:0)
O-Phosphoethanolamine
PA(16:0/16:0)
PE(16:0/16:0)
Acyl-CoA:lyso-phospholipid acy...
CTP-dependent diacylglycerol k...
Ethanolamine kinase
Ethanolaminephosphotransferase...
Glycerol-3-phosphate O-acyltra...
Lipase 4
Lysophosphatidic acid:oleoyl-C...
NADPH-dependent 1-acyldihydrox...
Phosphatidic acid phosphohydro...
phosphoethanolamine cytidylylt...
Probable 1-acyl-sn-glycerol-3-...
Inositol Metabolism
Inositol (also known as myo-inositol) is a carbocyclic polyol that can be found in many food such as nuts and beans. Inositol (e.g. inositol phosphates, etc.) can act as secondary messengers in eukaryotic cells. Inositol can be synthesized from three resources: inositol monophosphatase 1 can catalyze D-Myo-inositol 4-phosphate, myo-inositol 1-phosphate and 1D-myo-Inositol 3-phosphate to form inositol with water as cofactor.
1,2-diacylglycerol
1-Phosphatidyl-1D-myo-inositol...
1-Phosphatidyl-D-myo-inositol
1D-Myo-inositol 1,3,4,6-tetrak...
1D-Myo-inositol 1,4-bisphospha...
1D-myo-Inositol 3-phosphate
D-Myo-inositol 4-phosphate
Inositol 1,3,4,5,6-pentakispho...
Inositol 1,3,4,5-tetraphosphat...
Inositol 1,3,4-trisphosphate
myo-Inositol
Myo-inositol 1-phosphate
Myo-inositol hexakisphosphate
Phosphatidylinositol-3,4,5-tri...
1-phosphatidylinositol 3-phosp...
1-phosphatidylinositol 4,5-bis...
Inositol monophosphatase 1
Phosphatidylinositol 3-kinase ...
Phosphatidylinositol 4,5-bisph...
Polyphosphatidylinositol phosp...
Serine/threonine-protein kinas...
Vacuolar protein sorting-assoc...
Vacuole morphology and inherit...
N-Glycan Biosynthesis
The N-glycan biosynthesis is a pathway involving the creation of a dolichol, and the consecutive reactions involving the addition of Acetylglucosaminyl groups, mannosyl groups and glucosyl groups. The set of reactions all happen in the ER membrane. The resulting glucosyl3mannosyl9-N-acetylglucosaminyl2-diphosphodolichol is used as protein modificator.
N-acetyl-α-D-glucosaminyl-dip...
(Glucosyl)2(mannosyl)9-(N-acet...
(Mannosyl)2-(N-acetylglucosami...
(N-Acetylglucosaminyl)2-diphos...
Dolichol phosphate
Dolichol-20
Dolichyl b-D-glucosyl phosphat...
dolichyl β-D-mannosyl phosphat...
Glucosyl-(mannosyl)9-(N-acetyl...
Guanosine diphosphate mannose
Mannosyl-(N-acetylglucosaminyl...
Uridine 5'-monophosphate
Uridine diphosphate-N-acetylgl...
Alpha-1,2-mannosyltransferase ...
Alpha-1,3/1,6-mannosyltransfer...
Chitobiosyldiphosphodolichol b...
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2...
Dol-P-Man:Man(5)GlcNAc(2)-PP-D...
dolichol kinase
Dolichol-phosphate mannosyltra...
Dolichyl pyrophosphate Glc1Man...
Dolichyl pyrophosphate Man9Glc...
Dolichyl-phosphate beta-glucos...
GDP-Man:Man(3)GlcNAc(2)-PP-Dol...
UDP-N-acetylglucosamine transf...
UDP-N-acetylglucosamine--dolic...


text:
The Tech Submit Campus Life Stories Campus Tips Ig Nobels Reward Quirky Research
Join The Tech
Ig Nobels Reward Quirky Research
By Ramya Sankar Oct. 3, 2008
Ig Nobel Prize Laureate Dan Meyer swallows a sword for the audience. He won the Medicine Prize last year for investigating the side-effects of swallowing swords.
Biyeun M. Buczyk—The Tech
Marc Abrahams, the master of ceremonies of the Ig Nobel Prize Ceremony, is hit with paper airplanes as he announces the next Ig Nobel winner.
Spermicidal cola, archeological armadillos, and lap dancers were the talk of the evening at last night's Ig Nobels, where a weird ceremony feted the weirdest science of the past year.
Like real Nobel Prizes, the Ig Nobels award the most novel discoveries in the field of science and humanities. But the Ig Nobels are, well, decidedly less noble.
Redundancy was the theme of this year's event, held at Sanders Theater at Harvard University to a sold out, screaming crowd. Cheers erupted whenever the word "redundancy" was mentioned — which was often.
The pre-ceremony program began with a concert by Paul and Storm, followed by remarks by Master of Ceremonies Marc Abrahams, editor of the Annals of Improbable Research. Next was a parade of the "Indignitaries," individuals who came as a group dressed in their themed attire. The last group to parade through were members of the Boston Museum of Bad Art with art in hand.
Anna Lysyanskaya, Dany Adams, and William Lipscomb spoke in the "24/7" lecture series: spending 24 seconds giving a technical explanation of their work, followed by a seven word summary in layman's term (for the sake of redundancy). Lysyanskaya, Professor of Computer Science at Brown University spoke about Cryptography, Adams, biologist at the Forsyth Center for Regenerative and Developmental Biology, spoke about armadillo reproduction and finally Lipscomb, 1976 Nobel Laureate in Chemistry, spoke about redundancy.
The award show was also interleaved with a three act opera about (what else!) redundancy.
Winners of the dubious Nobel received of a paper certificate and a wooden board with a generic label. Whenever acceptance speeches went over their allotted time, a little girl named "Miss Sweetie Poo," would run to the microphone and proclaim "Please Stop, I'm Bored."
By the end of the ceremony, the theatre was filled with paper airplanes that were thrown during two designated times as well as intermittent periods throughout. The ceremony ended with the final act of the Opera and a photo-op of all the winners. The winners of the awards also got to shake the hands of Lipscomb, an actual Nobel Laureate.
With the closing remarks, Abrahams stated, as in tradition, "If you didn't win a prize — and especially if you did — better luck next year!"
Kees Moeliker, Dan Meyer, Francis Fesmire, and Don Featherstone, all former Ig Nobel Prize recipients were present.
This year's winners of the award include:
Massimiliano Zampini (University of Trento, Italy) and Charles Spence (Oxford University) for their research titled "The Role of Auditory Cues in Modulating the Perceived Crispness and Staleness of Potato Chips." This allowed them to change the crunching sound to make it seem like the chip was crisper than it really was.
The Peace Prize went to The Swiss Federal Ethics Committee on Non-Human Biotechnology for their recognition of dignity for plants. The award was accepted by Urs Thurnherr, a committee member.
Astolfo G. Mello Araujo and José Carlos Marcelino (Universidade de São Paulo, Brazil) were given the Archeology Prize for their study of how Armadillos can "scramble" up an archeological dig site.
The Biology Prize went to Marie-Christine Cadiergues, Christel Joubert, and Michel Franc (Ecole Nationale Veterinaire de Toulouse) for discovering that "fleas on dogs jump higher than fleas on cats."
Dan Ariely (Duke) took the award in Medicine for showing that "high-priced fake medicine is more effective than low-priced fake medicine."
Toshiyuki Nakagaki, Ryo Kobayashi, Atsushi Tero travelled from Japan to receive the prize in Cognitive Science for showing that "slime molds can solve puzzles."
Geoffrey Miller and Brent Jordan took the prize in Economics for showing that "lap dancer's ovulatory cycle affects tip earnings."
Dorian Raymer, physics, proving mathematically that heaps of string or hair or almost anything else will inevitably tangle themselves up in knots.
Deborah Anderson, Joseph Hill, C.Y. Hong's daughter Wan Hong (chemistry) Conflicting studies on Coca-Cola being a spermicide.
David Sims, Literature, "You Bastard: A Narrative Exploration of the Experience of Indignation within Organizations."
The Ig Nobel awards were first given out in 1991 and originally held at MIT. The purpose of the award is to celebrate the "unusual, honor the imaginative, and spur people's interest in science," according to the nomination form.
At the Ig Informal lectures tomorrow the new laureates will give 5-minute presentations of their award-winning work. The event will take place in 10-250 at 1:00 p,m., and is free and open to the public.
84 Massachusetts Ave, Suite 483
© 2019 The Tech


The U.S. Commerce Department lifted a ban on Chinese smartphone maker ZTE on Friday after it paid a $1.4 billion penalty levied by the U.S. government.
The ban was imposed in April after Commerce Department officials said ZTE made false statements about disciplining 35 employees after it pleaded guilty previous year to violating USA sanctions by illegally shipping US goods and technology to Iran, the Commerce Department said. Because ZTE relies on USA suppliers to make its smartphones.
Shen Meng, director of boutique investment bank Chanson & Co, said the overwhelming response from the stock market reflects the optimism that ZTE is on the way back to business. Three interlocking elements - a suspended denial order, the $400 million in escrow, and a compliance team selected by and answerable to the Department - will allow the Department to protect USA national security. The new agreement once again imposes a denial order that is suspended, this time for 10 years, which BIS can activate in the event of additional violations during the ten-year probationary period.
The sanctions influenced ZTE's decision recently to cease operations, and eliminate its entire board and appoint a new chairman. The latest $1.4 billion deal comes on top of that. Last month, the Senate voted unanimously to reinstate the ban on the company citing national security concerns. Many U.S. lawmakers see the company as a national security threat.
The U.S. Senate paved the way for a showdown with Trump over the issue last month, when it passed an annual defense policy bill with an amendment attempting to reverse the deal.
"ZTE must resume its business as soon as possible, given that the final sprint toward the commercialization of fifth-generation mobile communication technology kicked off in the middle of June".
Reuters reported on US demands for a deal on June 1, and on June 5, revealed that ZTE had signed a preliminary agreement with the Commerce Department, along with the fine and other terms.
Shares of ZTE in Shenzhen also surged by the maximum daily 10 percent following the announcement of the news.
The export ban, imposed earlier this year, effectively crippled ZTE by prohibiting USA companies from selling products or services to it.


text:
function replace_vars(){

    local SOURCE_FILE="/etc/dragonfly/manager.yaml"
    local VARS="\$DRAGONFLY_MANAGER_ADDR \$DRAGONFLY_MYSQL_USER \$DRAGONFLY_MYSQL_PW \$DRAGONFLY_MYSQL_HOST \$DRAGONFLY_MYSQL_DBNAME \$DRAGONFLY_REDIS_HOST \$DRAGONFLY_REDIS_PW"
    local TEMP_OUTPUT

        # Check if source file exists
    if [[ ! -f ${SOURCE_FILE} ]]; then
        echo >&2 "File ${SOURCE_FILE} not found."
        exit 1
    fi

    # Replace variables from temp variable and
    # outputs to the source file
    TEMP_OUTPUT=$(cat ${SOURCE_FILE} | envsubst "${VARS}")
    echo -n "${TEMP_OUTPUT}" > "${SOURCE_FILE}"

    # If it fails, exit with error, otherwise exit with success.
    if [[ "$?" -ne 0 ]]; then
        echo >&2  "Error parsing file."
        exit 1
    fi
}

replace_vars

/opt/dragonfly/bin/server

redpajama_set_name: RedPajamaGithub


text:
Dr. Ron's Research Review – November 6, 2013
This week's research review focuses on Betaine HCl for Gastric re-acidification.
A recent study used oral rabeprazole (Aciphex, a PPI) to induce hypochlorhydria in six healthy volunteers. Gastric pH was monitored continuously using the Heidelberg pH capsule. (Yago, Frymoyer et al. 2013)
After gastric pH > 4 was confirmed for 15 min, 1500 mg of betaine HCl was given orally with 90 mL of water.
Betaine HCl significantly lowered gastric pH by 4.5 (+/-0.5) units from 5.2 (+/-0.5) to 0.6 (+/-0.2) (P < 0.001) during the 30 min interval after administration. The onset of effect of betaine HCl was rapid, with a mean time to pH < 3 of 6.3 (+/-4.3) min. The re-acidification period was temporary with a gastric pH < 3 and < 4 lasting 73 (+/-33) and 77 (+/-30) min, respectively.
This study was conducted by the Department of Bioengineering and Therapeutic Sciences at the University of California, San Francisco.
Genentech funded this study.
A follow-up study is under way using betaine HCl to improve the absorption of dasatinib (Sprycel), an anti-cancer drug.
Note: The dose is equivalent to about 3 caps of Green Medicine's Betaine HCl with Pepsin, which contains 648 mg/cap.
Gastric Reacidification with Betaine HCl in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria
(Yago, Frymoyer et al. 2013) Download
Previous studies have demonstrated that increased gastric pH from the use of acid-reducing agents, such as proton-pump inhibitors or H2-receptor antagonists, can significantly impact the absorption of weakly basic drugs that exhibit pH-dependent solubility. Clinically practical strategies to mitigate this interaction have not been developed. This pilot study evaluated the extent and time course of gastric reacidification after a solid oral dosage form of anhydrous betaine HCl in healthy volunteers with pharmacologically induced hypochlorhydria. Six healthy volunteers with baseline normochlorhydria (fasting gastric pH < 4) were enrolled in this single period study. Hypochlorhydria was induced via 20 mg oral rabeprazole twice daily for four days. On the fifth day, an additional 20 mg dose of oral rabeprazole was given and gastric pH was monitored continuously using the Heidelberg pH capsule. After gastric pH > 4 was confirmed for 15 min, 1500 mg of betaine HCl was given orally with 90 mL of water and gastric pH was continuously monitored for 2 h. Betaine HCl significantly lowered gastric pH by 4.5 (+/-0.5) units from 5.2 (+/-0.5) to 0.6 (+/-0.2) (P < 0.001) during the 30 min interval after administration. The onset of effect of betaine HCl was rapid, with a mean time to pH < 3 of 6.3 (+/-4.3) min. The reacidification period was temporary with a gastric pH < 3 and < 4 lasting 73 (+/-33) and 77 (+/-30) min, respectively. Betaine HCl was well tolerated by all subjects. In healthy volunteers with pharmacologically induced hypochlorhydria, betaine HCl was effective at temporarily lowering gastric pH. The rapid onset and relatively short duration of gastric pH reduction gives betaine HCl the potential to aid the absorption of orally administered weakly basic drugs that exhibit pH-dependent solubility when administered under hypochlorhydric conditions.
Yago, M. R., A. R. Frymoyer, et al. (2013). "Gastric Reacidification with Betaine HCl in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria." Mol Pharm. [PMID: 23980906]


text:
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Stories Diary Picks About Press Contact
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Lisa Smosarski
Image courtesy of Lisa Smosarski
OccupationEditor-in-Chief, Stylist
Socials Twitter , Instagram
Websitehttps://www.stylist.co.uk
Learning Lisa Smosarski's style story.
Stylist Magazine may just be one of our favourite publications to look out for. Each issue is covered by women who inspires us – Dolly Alderton, Simone Ashley, and Michaela Coel, to name a few. As the magazine has been helmed by Lisa Smosarski for over 10 years, since it's inception, it's safe to say that we're huge fans of her work.
As the award winning editor-in-chief, Lisa has launched in conjunction with Stylist, big initiatives on behalf of the magazines audience. They include campaigns to end sexism and improve financing to women's sports, a project encouraging more inclusivity and diversity within women's media and advertising, and an initiative to support mental health while navigating the pandemics new work environment.
She also was co-host of the podcast, Letter to My Friend with Alix Walker, a podcast meant to celebrate our closest friendships.
With an affinity for Chloe boots and black denim, her style is also right up our alley.
How do you start your day off?
Slowly! I am not a morning person at all, but I have three children, so I don't have much choice but to wake up and get up. I can't really speak until I've had a cup of tea (English Breakfast) and then it's go, go, go!
What's going on in the background when you are getting ready?
Generally some sort of child-based chaos. Requests for fancy plaits, lost school uniforms or trying to recall everything my kids needed whilst planning my own day. I have very little time to get ready so it's not a particularly relaxing routine, which means I've often planned what I'm going to wear the night before. At the weekend, I'll put on BBC Radio 6 Music, I especially love Cerys on a Sunday morning – that feels like a real treat to get ready to.
What are your closet essentials?
Anyone who knows me will be stunned if I ever wear colour, as my essentials are generally all black, grey or if you're lucky, a splash of white. My essentials have been with me for years; they're fantastically timeless: black blazers, black jeans in lots of different cuts, an array of neutral t-shirts and lots of black boots. My Chloe Susanna boots and Frame jeans are my go-to for when I can't work out what to wear.
What is your biggest fashion regret?
I was about to say I have no regrets – most fashion blips only come with hindsight and are so often dictated by trends or fun explorations of the time – but then I had a sinking feeling as I remembered speaking at a huge magazine event in New York in a simple brown ribbed vest top. I was in my 20s and I can't even recall what look I was trying to channel, but beach chic was not anywhere near the dress code. Honestly, it was just such an odd choice for a formal event. If I could go back in time, I would definitely have handed myself a nice black blazer.
You always splurge on, and you always save on…
I splurge on accessories – shoes, bags, sunglasses – oh and coats. They're things that will last a lifetime and I can pass on to my children one day. I save on anything that seems particularly 'on-trend' as inevitably, it will be 'off-trend' again quickly. Despite strong beliefs that you should dress for yourself, I am not immune to a fantastic fad.
What is one piece of clothing you wish you could steal from your 16 year old self?
I had an amazing pair of Levi 501s that would be perfect this year and nothing matches that weathered old-school denim. Also, this crazy pair of black Patrick Cox jelly candles with an Eiffel Tower in the heel. I'm not sure I'd wear them but I'm amazed I got rid of them. They're just such a fun moment in fashion history.
What inspires your style most?
Emmanuel Alt can do no wrong, so I think I'll always covet her style. She's effortlessly chic always and I applaud her love of black day-to-day. My friends and colleagues probably inspire me the most – seeing how people put their looks together and remain so true to a style – I find that always really inspiring.
Your #1 style tip is…
Be yourself and wear what you love; trends are ideas not gospel. You can try someone else on for a day, but you'll never be as happy as you are in the clothing that make you feel like you.
*IMAGES COURTESY OF LISA SMOSARKI
Amy Nobile
Learning Amy Nobile's style story. Amy Nobile is a dating coach unlike any other dating coach. She's a dating coach...
Amy Appleton Dreyer
Learning Amy Appleton Dreyer's style story. Amy Appleton Dreyer wears many hats – mother, model, stylist and art director, as...
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Anor scores 2 to lift Crew to 2-1 win over Union
BY foxsports • March 22, 2014
COLUMBUS, Ohio (AP) Columbus Crew midfielder Bernardo Anor said his first goal off a set piece was one that had been run over and over again in practice.
His second wasn't the kind that can be duplicated in training.
Anor's brilliant 35-yard strike at the end of the first half proved to be the difference in Columbus' 2-1 victory over the Philadelphia Union Saturday in the Crew's home opener.
''That's what the game's all about,'' he said of the score that gave him his first multi-goal game of his career. ''It's something you don't practice very often. I was fortunate to score the goal.''
Anor previously had six goals in 45 games, including four in 20 games last season.
Columbus won the first two games of the season for the first time in its 19-year history while the Union fell to 1-1-1.
Leonardo Fernandes scored in the 62nd minute for Philadelphia to cut the deficit, but the first-half struggles were too much to overcome and Columbus goalkeeper Steve Clark made late saves on Fernandes and Jack McInerney.
''The team last year might have crumbled a bit,'' Union goalkeeper Zac McMath said. ''We came back and deserved a tie, if not a win.''
Anor gave the Crew a 2-0 lead in the second minute of first-half stoppage time.
The goal was set up when Wil Trapp created a turnover at midfield and poked the ball ahead to Anor for the quick strike.
''Our philosophy is to try and win the ball back as soon as possible,'' Trapp said. ''I stepped into the lane and Bernardo had a beautiful strike. I was lucky to get an assist. He was the one that did all the work.''
Columbus used its first corner kick to take the lead. Federico Higuain whipped the ball from the right to Anor, who was unmarked at the edge of the goal box. Anor had waited for several of his teammates to make runs through the box to draw attention.
Anor was the trailer and Higuain laced a perfect ball that Anor headed down into the goal.
''We lost our man,'' Union coach John Hackworth said. ''We should have had an easy clearance on the goal, too. Neither one of those should have happened.''


"What's New?" hosted by Carrie Zeffiro on TV Cogeco Niagara recently interviewed representatives from the Niagara Health Expo in the station's Niagara Falls studio. Event producer Paul Carfagnini joined Dianne Henderson from the presenting sponsor Gluckstein Lawyers to talk about what's new at the Expo.
September 24 at 6 p.m.
September 28 at 6 p.m.
Paul mentioned a few highlights of the event to be held at the Hotel Dieu Shaver Health and Rehabilitation Centre in St. Catharines on October 1 from 10 am to 3 pm. A key point in the show emphasized the collaboration of local doctors and healthcare providers to connect with people of all ages at the community event with free admission and free parking. Paul also highlighted the wide range of services to be promoted at the health fair with 30 exhibitors offering expertise on healthcare from head to toe.
Dianne Henderson, Medical Consultant at Gluckstein Lawyers (Presenting Sponsor of the event) also joined the show as a special guest. In the TV interview, Dianne previewed the presentation she will make at the upcoming Expo, "Managing Your Recovery in Ontario." The expert speaker session scheduled for 10:30 am on October 1 at the Expo will feature Dianne with important information to help the audience understand who funds health care when a sudden injury or illness occurs; and who will assist in decision-making about health care options. Dianne mentioned that all attendees at the speaker session will receive a complimentary copy of a booklet containing a variety of helpful information related to personal injury in Ontario, Managing Your Recovery in Ontario, A Self-Advocacy Guide.
What's New on TV Cogeco takes a look at the incredible individuals and organizations from across Niagara that make our community such a great place to live. Tune into Carrie's show Wednesday and Saturdays at 6 PM and Sundays at 1PM – chances are good you might hear of something that will interest you such as the Niagara Health Expo on October 1.


Members at Kings Premier Health Club can now benefit from a new state-of-the-art fitness monitoring system to help them achieve their health and fitness goals.
Myzone physical activity belts use personalised heart rate readings to inform members of the intensity levels of their workouts in real time, with the option to display their results on screens around the Club.
Members are also able to record and track their information from session-to-session to see precisely how they are progressing over a period of time.
An online personal activity report, accessible either online, or via the free Myzone app also enables them to log in at any time to see how close they are to reaching their goals.
"It's brilliant news for Kings. We have been looking for a training tool to bring additional value to our offerings and Myzone enables us to do just that. People come to us looking for results, and that is exactly what Myzone is all about".
Myzone taps into people's competitive instincts as well. The more time spent exercising and the higher the intensity of the exercise, the more Myzone Effort Points members earn. They can then participate in challenges to earn prizes, all while improving their overall fitness level.
"It's a great motivator" said Sean. "It enables you to set personal goals, and holds you accountable to them. By giving you feedback on how intense your workouts actually are, it's really effective at helping track progress. Ultimately, this will lead to members achieving the results they've been looking for and getting the most out of their Club."
For more information about MyZone, please visit www.kings.gg/myzone.


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University of Aberdeen: Alcohol pricing in Scotland – does it affect your food shopping?
By iednewsdesk	 On Jan 15, 2022
Do consumers spend less on food if the price of alcohol goes up? Has Minimum Unit Pricing for alcohol actually changed consumers' shopping choices? These are just a couple of the questions discussed in the latest Café Connect podcast from the University of Aberdeen.
Professor Paul McNamee from the Health Economics Research Unit at the University of Aberdeen and Lucie Giles, Public Health Intelligence Principal from Public Health Scotland, talk about the impact of Minimum Unit Pricing for alcohol in Scotland and the latest research due to come out on the subject.
Alcohol Minimum Unit Pricing (MUP) was introduced in Scotland in May 2018 as part of the Scottish Government's strategy to reduce the health and social harms associated with alcohol misuse. In this conversation the experts look at a range of issues, including research to understand whether household food spending could change following the introduction of MUP and the effect that this may have on diet quality.
Professor McNamee explains: "Our research on Minimum Unit Pricing forms part of a portfolio of research on health behaviours looking at policy and its impact on health behaviours.
"This study looks at whether the policy has an unintended impact on food shopping and diet. We are looking at data from some eight thousand households, comparing the shopping habits of people in Scotland before and after the introduction of MUP with households in the North of England.
"As well as spending – we also look at the nutritional impacts associated with their shopping.
"Our work is still ongoing but some earlier modelling suggested a rise in spending on alcohol amongst some households, so there is some concern around other unintended impacts of the policy – if consumers are spending more on alcohol – are they buying less food?
"Once we have completed our study we will feed back to policy makers in Scottish Government who will use it alongside other evidence to consider whether MUP should be retained in Scotland – watch this space!"
University of Aberdeen: Primary pupils turn marketing pros with help from Business School
University of Aberdeen: University academics granted prestigious RSE funding awards


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It was the biggest moment in Austin Robichaux's life. But for the next 10 hours, he had to pretend it wasn't.
The euphoria of being drafted in the Major League Baseball First-Year Player Draft by the Los Angeles Angels earlier in the day was a career moment for the UL junior right-hander. But he and his dad, UL head coach Tony Robichaux, had to keep that happiness bottled up so Austin can concentrate on getting the Ragin' Cajuns one step closer to the College World Series.
So after being selected by the Angels in the 18th round (539th overall), Austin Robichaux pitched seven strong innings to help UL beat Ole Miss 9-5 in the first game of their NCAA Super Regional series on Saturday night.
Austin did get off to a rocky start as the Rebels got three runs off of three hits in the second inning to take a 3-0 lead. But while his teammates put up five runs in the third inning to put UL up 5-3, Robichaux gave up only three hits and two runs the next five innings.
"I thought Austin Robichaux, after maybe struggling in the first couple of innings, really found himself and got deep into the game, which is what you want from your ace," Ole Miss head coach Mike Bianco said.
Austin knew that his teammates would pick him up after his rough start.
Ole Miss presented a small challenge to Robichaux because the Rebels are not only a good hitting team, but do it from the left side of the plate. Five batters in the Rebel lineup hit left-handed, which presented a tough matchup. But Austin kept his poise and – along with the help of 4,278 of his friends in vermilion and white – was able to keep the Ole Miss bats at bay.
Although he and his teammates are focused on Sunday's game and trying to lock down the program's first CWS berth in 14 years, Austin did finally get to reflect on the thrill of being drafted into the major leagues, especially since he was drafted to the same team with his teammate, outfielder Caleb Adams.


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Home › Cervical Health › CerviCAN Support Program
ACCF's CerviCan Support Program supports Australian women and their families who have been diagnosed with cervical cancer. With over 900 women diagnosed with cervical cancer each year in Australia, ACCF is often the first point of contact for these women after their diagnosis. ACCF offers support, information and resources to help these women and their families at this stressful and scary time.
Due to COVID-19, the ACCF team are currently working from home but we are checking messages and emails regularly. If you or someone you know has been recently diagnosed with cervical cancer and you need support please call 1300 727 630 and leave a message or please click here to send an email with your contact details and we'll get back to you as soon as possible.
Faces of Cervical Cancer Support Booklet
ACCF is thrilled to announce the launch of the Faces of Cervical Cancer- Support Booklet. This is for women and families affected by cervical cancer. It includes information, resources and stories from women who have walked this path and continue to do so. We hope it gives you the information you need at this time. A printable version will be available soon.
Diagnosis Support
CancerAid
ACCF is proud to be a partner of CancerAid who work to empower cancer patients and their caregivers by providing a unique cancer management and support application. Available on iPhone and Android for free, tools varying from a symptom tracker to a personal journal is accessible to the user. Read more here.
Cancer Council Online Community is a free, professionally moderated online support community where people living with and affected by cancer can find, receive and provide support by participating in groups, discussions, blogs and webinars. You can join the forums here.
Healthshare
Healthshare is an online support community that enables you to connect and share with other people around Australia. By joining the Australian Cervical Cancer Foundation's Healthshare Community, you will be able to ask questions, share your personal experience, find support within the community, and access high quality information about cervical cancer. Click here for more information about Healthshare, visit their cervical cancer page, and have a look at ACCF's community for further information and to connect with people who know what you are going through.
Facebook Support Group (AU/NZ)
This Facebook page has been created to provide an active, supportive group of women made up of over 600 members from Australia and New Zealand who have, or have had Cervical Cancer, or other gynaecological cancer, issues. The page offers women a place to come together for support, understanding, love, humour, and above all friendship. Also open to carers, family and your support network.
If you would like to join this group please follow this link https://www.facebook.com/groups/644503988935517 and submit your request to join.
Counterpart Gynaecological & Breast Cancer Support
Counterpart is an information and support service for Victorian women living with breast or gynaecological cancers, including cervical cancer. They provide a range of information and support services through their city based Resource Centre, digital and outreach projects. They support women with cancer to live well, along with their family and friends. Counterpart offers women a holistic, women-centred, community based service that works in tandem with their medical systems and existing support systems. They offer a confidential, free service. Counterpart is a service of Women's Health Victoria and is supported by the Victorian Department of Health and Human Services.
NB: Women living outside of Victoria can still register for any Counterpart webinars that are of interest to them.
For more information visit their website www.counterpart.org.au
Cancer Council Australia
Cancer Councils coordinate a network of cancer support groups, services and programs to help improve the quality of life of cancer patients, people living with cancer, their families and carers.
They provide information about all aspects of cancer to cancer patients and the general community, through Cancer Council 13 11 20.
To contact the Cancer Council in your state or territory visit: http://www.cancer.org.au/about-us/state-and-territory-councils/
Cancer Council NSW has produced 10 informative podcasts for those affected by cancer, including family & friends. Topics include: "Explaining Cancer to Kids", "Appetite Loss & Nausea" & "New Cancer Treatments: Immunotherapy & Targeted Therapy". Podcasts can be accessed via https://www.cancercouncil.com.au/podcasts/
Look Good Feel Better for women is a free community service program that provides useful information and tips specifically tailored to help women deal with the appearance-related side effects of cancer treatment. Home-delivered Confidence-Kits are a supplementary service developed to assist cancer patients who are unable to attend a Look Good Feel Better workshop for health, travel or personal reasons. Visit their website here.
Work & Financial Support
The Work after Cancer website is a resource to support work during and after cancer diagnosis, providing advice to people diagnosed with cancer, their loved ones, clinicians and employers about their options, rights and responsibilities.
This website also offers information relating to financial assistance for people diagnosed with cancer and their families.
Mummy's wish
Mummy's wish aims to support Australian families with children aged 12 years and under, through the provision of immediate and non-means tested support whilst mum is receiving treatment for cancer. They can give you a call to chat through advice on how to juggle cancer treatment and family commitment, help with housework and many other practical tasks. Contact them here.
CanTeen supports those aged 12-25 whose world has been turned upside down by cancer, including those with a parent who has cancer. For more information click here.
Cervical Cancer Information
Cancer Council Australia or call them on 13 11 20
Health Direct: Cervical Cancer
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Cervical Cancer – Cancer Council NSW
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Positive Health and Wellness
Counterpart (see info under "Support Groups" above) conducts some information sessions which are also offered as webinars. You can access videos of some of the webinars they have held in the past at Counterpart webinars
A Decade of Making a Difference
"In my opinion, HPV vaccination is a life-saver and it's …
An Open Letter to all Australians
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How to Protest Without Offending White People
http://www.theroot.com/how-to-protest-without-offending-white-people-1818770022
Don't Say 'White'
I have no idea why, but white people hate it when anyone uses the phrase "white people," because, for some reason, they consider it a pejorative. When protesting police brutality, education inequality, unfair housing practices or anything else, you must be careful not to "make it all about race"—even if the thing you're protesting is all about race.
Refer to racism as a "social issue." Instead of slinging the phrase "white supremacy" around all willy-nilly, you can instead refer to it as "structural inequality." If your "underprivileged" child has been fenced into a poorly funded educational system, call it an "inner-city school."
Uttering the words "white people" only serves as a reminder of their historic ties to oppression, which can only be negated by their instinctual regurgitation of the preamble to all white excuses: "Not all white people ..." Even if you make your protest about a "societal issue" that's not about race, you still shouldn't expect them to join in or approve.
They already heard you say "white people."
It goes on. Good stuff.
Posted by WhiskeyGrinder | Tue Sep 26, 2017, 09:40 AM (30 replies)
Roald Dahl wanted "Charlie and the Chocolate Factory" hero to be black
http://www.bbc.com/news/entertainment-arts-41257684
Liccy Dahl told BBC Radio 4's Today programme her husband had written about a "little black boy".
But Dahl's agent thought the idea a bad one and insisted the character be changed - something Dahl's widow said was a "great pity".
She said seeing the 1964 children's book as her husband had intended it would be "wonderful".
"It was his agent who thought it was a bad idea, when the book was first published, to have a black hero," said Sturrock. "She said: 'People would ask why.'"
Posted by WhiskeyGrinder | Thu Sep 14, 2017, 07:12 PM (8 replies)
Woman works to become historian in prison, is released, gets accepted to Harvard -- then rejected.
Michelle Jones was released last month after serving more than two decades in an Indiana prison for the murder of her 4-year-old son. The very next day, she arrived at New York University, a promising Ph.D. student in American studies.
In a breathtaking feat of rehabilitation, Jones, now 45, became a published scholar of American history while behind bars, and presented her work by videoconference to historians' conclaves and the Indiana General Assembly. With no internet access and a prison library that skewed toward romance novels, she led a team of inmates that poured through reams of photocopied documents from the state archives to produce the Indiana Historical Society's best research project last year. As prisoner No. 970554, Jones also wrote several dance compositions and historical plays, one of which is slated to open at an Indianapolis theater in December.
N.Y.U. was one of several top schools that recruited her for their doctoral programs. She was also among 18 selected from more than 300 applicants to Harvard University's history program. But in a rare override of a department's authority to choose its graduate students, Harvard's top brass overturned Jones's admission after some professors raised concerns that she downplayed her crime during the application process.
Elizabeth Hinton, one of the Harvard historians who backed Jones, called her "one of the strongest candidates in the country last year, period." The case "throws into relief," she added, the question of "how much do we really believe in the possibility of human redemption?"
https://www.themarshallproject.org/2017/09/13/from-prison-to-ph-d-the-redemption-and-rejection-of-michelle-jones#.PNEDw47he
Posted by WhiskeyGrinder | Thu Sep 14, 2017, 08:18 AM (9 replies)


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I just wanted to make a note that this community section is still a work in progress. It's a little clunky and has some kinks, but it's a start! Expect some little changes as I work to improve things in the coming weeks.
If you see something that might need a tweak, let me know here!
Well for one, every word is capitalized. I don't mind. But Carrot the grammer dude might.
Yeah, I noticed that too. Trust me… I'm looking into it today!
Just out of curiosity, what extra benefits does creating an account have?
No big difference, really. The main benefit is that you wouldn't have to type in your email address every time you posted.
I already don't have to do that due to cookies or something… would I get to have a different avatar?
You get to pick a picture to put in.
Sweet. I'm getting a little tired of Midlife Crisis Ghost.
I don't like signing up for things, so I will be toast brain monster for a while.
Haha, thank goodness! This capitalization makes me think of bad Youtube comments.
If I do sign up for an account, I may keep my picture. I'm rather fond of my little floating crabbit-bandit. Would there be a way to get notifications if someone replied to you like there is on comments? I don't know much about WordPress or their discussion boards.
Brooke, you can subscribe to a thread, but I'm not sure what that does.
Do all accounts show up as an admin, whether we're actually capable of editing anything or not?
Note: you have to set up a Gravatar if you want to have an avatar.
Signing up for all that stuff sounds like it'll take a few minutes…and I'm lazy.
Quill, from Legend of Zelda: Wind Waker. He's a Rito. Rito evolved from the Zora when Hyrule was flooded prior to Wind Waker. Because fish people turning into bird people when there is a flood makes tons of sense, right?
Ahhh, Mason and Carrot! Your pictures are cool! I don't see where I can subscribe to threads… Do you have to have an account to subscribe? Kristen, do you see how, since you don't have an account yet?
Mason! I love your picture!!!
I believe you do have to have an account to subscribe.


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Guadamur ist eine spanische Kleinstadt in der Provinz Toledo in der Autonomen Gemeinschaft Kastilien-La Mancha.

Lage
Guadamur liegt etwa 15 Kilometer (Fahrtstrecke) südwestlich von Toledo in der historischen Provinz La Mancha; bis nach Madrid sind es gut 90 Kilometer in nordöstlicher Richtung.

Bevölkerungsentwicklung

Die höchste Einwohnerzahl mit 2017 Personen hatte Guadamur im Jahre 1920.

Wirtschaft
Guadamur war das landwirtschaftliche Zentrum mehrerer kleinerer Gemeinden, Weiler und Einzelgehöfte. Bis auf etwa 90 ha bewässerter Ackerfläche, auf denen Melonen und Gemüse wachsen, wird in der Region Toledo – wie auch andernorts im Zentrum und im Süden Spaniens – ausschließlich Trockenfeldbau betrieben. Angebaut bzw. angepflanzt werden vor allem Getreide, Oliven und Wein. Im 18. Jahrhundert gab es in der Umgebung zwei Minen – eine zur Gewinnung von Bleierzen, die andere zur Gewinnung von Kohle.

Geschichte
In der Umgebung des Ortes wurden Spuren bronzezeitlicher und keltiberischer Siedlungen gefunden. In der römischen Antike war die Gegend in der Hauptsache ein Handelsweg von Süd nach Nord und von Ost nach West; Spuren römischer Landgüter (villae) wurden nicht entdeckt. Die Westgoten errichteten in Guarrazar, einem heutigen Vorort, eine bedeutende Ansiedlung, die nach dem Jahr 711 von den muslimischen Eroberern übernommen und fortgeführt wurde, die jedoch – außer einigen Ortsnamen und anders als im nur wenig entfernten Toledo – kaum archäologisch verwertbare Spuren hinterließen. Auf dem Weg zur siegreichen Schlacht von Las Navas de Tolosa zogen im Jahre 1212 die christlichen Heere durch das Gebiet, welches in der Folgezeit durch den Bau von Burgen und Wachtürmen gesichert wurde. Auf den Ruinen einer der frühen Befestigungsanlagen wurde im 15. Jahrhundert das imposante Castillo errichtet, welches die Zeitläufe überdauert hat.

Sehenswürdigkeiten

 Hauptattraktion des Ortes ist die spätmittelalterliche Burg Guadamur (castillo), die jedoch gut einen Kilometer östlich des Ortes liegt.
 Die nahe bei der Burg gelegene Einsiedlerkirche (ermita) Nuestra Señora de la Natividad stammt ursprünglich aus dem 13. Jahrhundert. Ihr Mauerwerk besteht aus mehreren Bruchsteinlagen, zwischen denen sich in Abständen von etwa 40 cm jeweils eine Lage aus Ziegelsteinen befindet. Das einschiffige Innere ist erst im 19. Jahrhundert eingewölbt worden. Von der Decke der Apsis hängen Kopien der in den Jahren 1858–1861 unweit von hier im Vorort Guarrazar gefundenen westgotischen Weihekronen, deren Originale im Archäologischen Museum in Madrid zu sehen sind.
 In einem alten Schulgebäude wurde ein Centro de Interpretatión del tesoro de Guarrazar eingerichtet, dass sich primär an jugendliche Besucher wendet.
 Die Pfarrkirche Santa María Magdalena war ursprünglich ein einschiffiger Bau des 16. Jahrhunderts, der im Jahre 1702 ein nördliches Seitenschiff erhielt. Der heutige dreischiffige Zustand wurde erst durch An- und Umbauten zu Beginn des 20. Jahrhunderts herbeigeführt.
 Eine spätgotische Gerichtssäule (rollo jurisdiccional oder picota) aus den Jahren 1468–1471 steht ganz in der Nähe.
 Die Ermita San Antón stammt ebenfalls aus dem 16. Jahrhundert und beherbergt heute ein kleines ethnographisches Museum zu den Lebensumständen früherer Zeiten und zur Volkskunst und Trachten in der Region der Montes de Toledo.

Partnerstädte
 Tournai (Belgien)
 Vouillé (Frankreich)

Weblinks

 Guadamur, Geschichte und Sehenswürdigkeiten – Infos (spanisch)

Einzelnachweise

Ort in Kastilien-La Mancha
Conjunto histórico-artístico


DC law firm, Williams & Connolly LLP, from 1996 to 2010. His cases included assisting in the firm's defense of former President Bill Clinton in investigations and the Senate Impeachment trial, individual-volunteer representation of former Vice President Al Gore in the 2000 election crisis, defense of a union president against charges of association with organized crime, and more than six years representing a professional firm in the Enron matter. Gil ended legal practice in 2010 and currently assists the firm with the training of younger lawyers and with issues involving electronic discovery.
Born in Massachusetts in 1967, Gil grew up in South Charleston, West Virginia, and moved to Bellevue, Washington, where he attended Interlake High School, graduating in 1985. He attended Columbia University in New York City and worked in Manhattan as a legal assistant. In 1994, in his third year at Harvard Law School, Gil was diagnosed with multiple sclerosis.
When someone tells me that they or a friend have MS, my mind immediately turns to what medications they have used.
Tysabri was very effective for me, but it is a powerful drug with risks that are closely monitored. Many more options are now available, but I believe without Tysabri I would have had many more active lesions and further damage.
Currently doing monthly Solumedrol infusiions and waiting for my white blood cell count to raise high enough that I can go back on Tysabri.
Severe heat sensitivity. Starting at 72 degrees F and worsening with every degree, numbness and pain commence then disorientation and blackouts. Humidity is exponentially worse. Air conditioning is not a complete solution but helps.
Weakness and foot drop in left leg — My walking ability has declined by about fifty percent a year. I am now only able to walk with a walkler or crutches up to about 50 paces under ideal conditions. I am using various physical and other treatments which will be described in other posts. These include at least four training sessions per week in Pilates and GYROTRONIC exercise at Studio Evolve in Seattle — studio-evolve.com. I began using an electric wheelchair in Jan. 2016.
No pain absent heat! No visual issues! A fortunate man indeed.


This CPO certification is valid for 5 years! Many city and county regulations require that your property has a CPO on site to care for your pools and spas. Even if it is not required it is still a very useful certification that will help keep your pools and spas safe and open. This class covers everything that is required by the NSPF but emphasizes how this certification is used in the multi-family industry.


text:
10 inspirational quotes by the "Missile Man" Dr. A.P.J. Abdul Kalam
By Muskan Bhatia	 On Jul 27, 2017
Known as the 'Missile Man' and the 'People's President', Dr APJ Abdul Kalam was an engineer, scientist, innovator, teacher, author, public speaker and the most affable Indian president who opened the gates of Rashtrapati Bhawan to the rank and files.
Dr Kalam was a visionary who envisaged India as a future superpower and he highlighted the role of education in nation building. He had an undying passion for interacting with students and teaching. He cultivated an interest in science for the youth.
Born the son of a fisherman in a small village in Tamil Nadu, Dr Kalam graduated in aerospace engineering and then went on head top notch scientific projects at both ISRO and DRDO. Dr Kalam was also scientific advisor to the Prime Minister of India Atal Bihari Vajpayee. He was the chief of the integrated guided missile development programme that gave us missiles like Agni and Prithvi. He was also associated with the Pokhran 2 nuclear tests in 1998.
Dr Kalam died of a cardiac arrest on 27th July, 2015 while addressing students at IIM Shillong. His last wish was that he wanted to continue teaching always.
Here are 10 inspirational quotes by Dr. Kalam:
APJ Abdul KalamInspirationalQuotes
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A lot of internet users are reusing the same password across multiple services. That gives hackers opportunity to use the passwords stolen from one service on another one.
On December 2017 massive passwords database was published. There is total of 1.4 billion of emails with passwords. Part of services where passwords was stolen is huge: Last.FM, Bitcoin, Pastebin, LinkedIn, MySpace, Netflix, YouPorn, Zoosk, Badoo, RedBox, games like Minecraft and Runescape, Anti Public, Exploit.in ….
We have purchased that list of all passwords and filtered our users. We force every affected user to change it passwords. It's only matter of time when somebody else will start using your email account if password will not be changed.
1. Don't use the same password for different services.
2. Use password manager software to remember all passwords and make it secure.
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