Rovio Stockholm is the studio behind the hugely popular Angry Birds 2, the bigger, badder, and birdier sequel to the global phenomenon that put Angry Birds on the map. Following up a phenomenon has been a huge challenge, and it has been extremely rewarding to see the game thrive. While we are soaring high on that success, and we continue to expand and improve that title, we are also developing new IPs and exploring new game ideas, specifically within the RPG genre.
Our mission is to become the best mobile RPG developer in the west. That's no small task, but we believe that we have a unique possibility to mix this studio's experience of creating accessible, inclusive mass-market games with our personal love for RPGs. Our design pillars are: dynamic, character-driven, and highly social. We are very motivated to create mid-core games that are both approachable and challenging.
In the Stockholm studio, we keep a flat hierarchy, a high level of transparency, and open communication. Our team is always trying to find ways to improve our projects, tools, communication, and ourselves, while keeping the atmosphere friendly, inclusive, respectful and super supportive. With paid overtime and basically no crunch we also respect each other's time. We make sure that we learn both from our mistakes and our success as we grow both in number and in experience. At the Stockholm Studio you will be working with great co-workers in a team-oriented, informal, international, and inspiring working environment.
"I am a father and an avid gamer. I started my career in the games industry 17 years ago by founding a startup pioneer in online multiplayer games in Brazil. After a few years living in Germany, I realised Berlin was not cold enough so I moved to Finland to be Head of Production for Rovio Stars. Early in 2017 I joined the outstanding team of Rovio Stockholm with the mission to deliver some of the best mobile RPGs in the west."


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Q: Add a file to a specific folder with gradle build I am currently working with a project (using gradle) that needs a properties file in the same package to the class that consumes it (I can't change this config). I have added the file in my package, but when I execute the gradle build command omits the file, and only adds the .class file. The app is deployed as a war file.
I have tried editing the war task, but I can't find the way to make the properties file to be added:
war {
        from('src/main/com/foo/bar') {
            include 'b.properties'
            into 'WEB-INF/classes/com/foo/bar'
        }
}

The war task does execute (I have added a prinln and it executes). Also, I have tried changing the paths, but no results. Also replacing from('path') to from (file('path')), but still doesn't seem to add the file anywhere.
How should I achieve this? Thanks!

A: Is there anything stopping you from following Gradle's convention for resources?
Eg put your property file at src/main/resources/com/foo/bar/b.properties
If you do this you won't need any task customisations

redpajama_set_name: RedPajamaStackExchange


Say goodbye to SLI / Crossfire??
Re: Say goodbye to SLI / Crossfire??
1500 watts?!!! wtf dude?! do you have a flux capacitor in there?!
But why would you? I mean if you have the money to run a 295 and a 295 why use a 4870x2?
its not that..... you could just add another gpu to whatever you have at the time.... and get a speed increase. One primary problem with SLI/crossfire is you have to buy two or more video cards. Many people would prefer to use it as a upgrade path, but many times you cannot or should not.
For instance, most of the time, say a year down the road, you could add another video card and go SLI.... but should you? Many times by the time a year or more has passed, you can just buy a single video card that will be faster than the two video cards you are considering running.... many times its not that much different in price either, and you can reuse or sell your old card.
I agree with Athran though, this thing sounds great... on paper.... I want to see it running and actually do what they claim.
This. I mean, I've got an 8800GT... should I get another 8800GT to toss in there in SLi? A single GTX280 would beat out dual 8800GT's anyday... HOWEVER, with this, I could just get a GTX280 and toss it in with my 8800GT, and still be able to *SLi* both of them sorta. Meaning I could still use my 8800GT instead of just tossing it in the closet for the time being.
Man, that would be awesome. I'd love to see one of these in action. I think I'd wait a while too to see how it starts out though.
I say screw Nvidia and boycott all their products. This is exactly the same thing they are doing atm with the Intel chipsets 955 and 975. Both of them as well as several others support SLi but b/c they dont have a sticker saying ***SLI CERTIFIED*** then you dont get to use SLi. They are greedy bastards if you ask me.
Nvidia = greedy whore bags. Nuff said.


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Q: Trouble deriving the general formula of complex trigonometric functions where $z \in \mathbb C$ is the argument I have successfully derived the equation $\sin(y)=\frac{e^{iy}-e^{-iy}}{2i}$ and its corresponding cosine partner $\cos(y)=\frac{e^{iy}+e^{-iy}}{2}$ where $y \in \mathbb R$.
In my book, the general equation for $z \in \mathbb C$ (of the form $z = x+yi$) is also provided for sine and cosine functions:
$$\sin(z) = \frac{e^{iz}-e^{-iz}}{2i}$$
$$\cos(z)=\frac{e^{iz}+e^{-iz}}{2}$$
I am having some difficulties deriving these equations. I'll show what I have so far for $\cos(z)$.
At the outset, note that $e^{ik}$ where $k \in \mathbb R$ is defined to be equal to $\cos(k)+\sin(k)i$
Firstly, we see that $e^{i*z}$ can be rewritten as $e^{i*(x+yi)}$, which is equal to $e^{-y+xi}$.
$$e^{-y+xi} = e^{-y}e^{xi} = e^{-y}(\cos(x)+\sin(x)i)$$
In a similar fashion, we know that $e^{-i*z}$ can be written as $e^{-y-xi}$.
Following a similar set of steps, $e^{-y-xi} = e^{-y}(\cos(-x)+\sin(-x)i)$
Recall that $\cos(-x)=\cos(x)$ and $\sin(-x)=-\sin(x)$. Therefore we have:
$$e^{-y}(\cos(-x)+\sin(-x)i) = e^{-y}(\cos(x)-\sin(x)i)$$

If we then add  $e^{-y+xi}$ to $e^{-y-xi}$ we get:
$$e^{-y+xi} + e^{-y-xi}=e^{-y}(\cos(x)+\sin(x)i) + e^{-y}(\cos(x)-\sin(x)i)$$
$$e^{-y+xi} + e^{-y-xi}=2*e^{-y}\cos(x)$$
Reverting back to our initial definitions of $z$ and $-z$ we have:
$$e^{iz}+e^{-iz}=2*e^{-y}\cos(x)$$
$$e^{-y}*\cos(x) = \frac{e^{iz}+e^{-iz}}{2}$$
And this is where I am completely stuck. The only thing I can think to do is make the following statement:
$$\cos(z) \stackrel{\mathrm{def}}{=} e^{-y}*\cos(x)$$
But that seems sort of hand wavy to me.
Any suggestions would be greatly appreciated!

A: To prove something about $\cos(z), \sin(z)$ you need first to define $\cos(z), \sin(z)$.
The formulas you are trying to prove are the usual definitions.
Alternatelly, you can prove the following result:
Lemma: There exists an unique entire function $f : \mathbb C \to \mathbb C$ such that
$$f(x) = \cos(x) \forall x \in \mathbb R$$
Moreover,
$$f(z)=\frac{e^{iz}+e^{-iz}}{2} \forall z \in \mathbb C$$
Proof Existence follows from the fact that $\frac{e^{iz}+e^{-iz}}{2} $. Uniqueness follows from the identity theorem for Analytic functions.
\qed
The above Lemma, allows you to alterately define $\cos(z)$ as the unique entire extension of $\cos(x)$ and derives the identity you want.
You can prove a similar result for $\sin(z)$.

A: The usual definition of $\sin(z)$ and $\cos(z)$ for $z \in \mathbb{C}$ is $\sin(z)=\frac{e^{i z}-e^{-i z}}{2i}$ and $\cos(z)=\frac{e^{i z}+e^{-i z}}{2}$.


I would like to express my thanks to Networx3 for the excellent work recently carried out at Network Rail and Conde Nast. It was noticeable how conscientious and flexible your engineers were throughout. We have found the quality of your cabling and of your work was of a consistently high standard.
Since Networx3 Ltd became GMP's official wiring contractor, we have received a consistently professional, knowledgeable and value for money service. All members of the team are very helpful and have a good understanding of the GMP Infrastructure. The team have a genuine 'happy to help' work ethic and have a broad spectrum of knowledge relating to all types of infrastructure typology, network hardware, installation and fault resolution. Networx3 have been very helpful in producing resolutions and plans for new network locations and 3rd party companies working alongside GMP. Ian and the team are a pleasure to work with, and continue to provide assistance and a great service with the ever expanding GMP Network.
We are delighted to deservedly promote Networx3 to Select Partner level. With loyal partners such as Networx3, we know end customers are guaranteed unrivalled levels of support and service.
Emtelle's partnership with Networx3 gives the advantage of having world class Blown Fibre products and World class installation teams who can install Blown Fibre systems for all FTTX solutions in the UK & Overseas. Networx3 success in new/ developing markets such as Fibre to the Home & Fibre to the Mast proves their ability to fully satisfy customers requirements with Emtelle's fibreflow solutions.


How to set your browser's home page to any website you prefer. Here's how to change the home page in Explorer, Edge, Google Chrome, Opera, safari & Firefox.... In my experience, when opening the Google Chrome browser, if it's not the "default" browser, a window will pop out telling you that it's not your default browser and will allow you to click a button to make it your default browser. I believe Microsoft Edge (which replaced Internet Explorer) will give you a similar pop-up window when you open it and it's not your default browser.
In my experience, when opening the Google Chrome browser, if it's not the "default" browser, a window will pop out telling you that it's not your default browser and will allow you to click a button to make it your default browser. I believe Microsoft Edge (which replaced Internet Explorer) will give you a similar pop-up window when you open it and it's not your default browser.
7/06/2016 · Then search your files and you will see that IE 11 is still an app on your PC. Open the old explorer and you can make the change to the settings. You might want to pin the old IE to the taskbar so you don't have to search for it every time.


A Yates County man accused of leaving a dog inside a hot car outside Clifton Springs Hospital is facing animal cruelty charges.
Robert McKay, 77, of Penn Yan was charged with animal cruelty and leaving a dog in a vehicle in extreme heat conditions according to the Ontario County Humane Society.
Officers were called to the vehicle, which was parked outside the Clifton Springs Hospital in Clifton Springs, around 11:10 a.m. Monday. A hospital employee spotted the dog, a Shar-pei mix named Mr. Rinkles who was in distress and removed the dog from the car.
The dog was immediately given water and placed in the shade before being taken to the Ontario County Humane Society.
Officials said the temperature inside the parked car reached 120 degrees.
McKay will face the charges in Clifton Springs Court at a later date.
http://www.fingerlakesdailynews.com/2018/07/03/154635/ reports that Rinkles came back to his car about an hour later.
Meant to say that it was Mckay, the owner, who returned an hour later.


One of the most wise adages of all times instructs us, "If you don't have anything nice to say, don't say anything at all." I have always fiercely loved that quote, and it's served me well throughout my life — especially in moments of anger.
Obviously, anger is not only an unpleasant feeling, but it can lead to unpleasant actions if we don't learn how to reign it in. Thankfully, while we may not be able to fully control our emotions, there is hope in knowing that we can control our actions. It can be difficult, but most things worth doing are.
So next time you feel the flame of anger burning within you, take a step back and consider these three tips.
The idea that we are not in control of our anger is a tool of the adversary. We are in control — we can choose to unleash our fury or we can choose to respond positively. If we genuinely struggle with "losing our temper" and truly feel out of control, we can choose to speak with our bishop, attend anger management courses, and seek other helpful resources.
At the end of the day, being unkind and treating others poorly is a choice.
In his sophomore year Wilbanks tried out for the high school basketball team and made it. On the first day of practice his coach had him play one-on-one while the team observed. When he missed an easy shot, he became angry and stomped and whined. The coach walked over to him and said, "You pull a stunt like that again and you'll never play for my team" (23). For the next three years he never lost control again. Years later, as he reflected back on this incident, he realized that the coach had taught him a life-changing principle that day: anger can be controlled.
Anger can be controlled. Through prayer, steadfast effort, and, most importantly, the Atonement of Jesus Christ, we can learn to harness those negative emotions and respond to difficult situations with kindness.
The first lesson we can learn from this story is that you shouldn't stomp on your hat. Very important. The second lesson, which is probably a little more important than the first, is that we can learn to laugh when life hands us a sour lemon.
It would have been easy for President Hinckley to get mad at the man in his story. After all, the guy wasn't working on anything, and President Hinckley had asked something pretty simple of him. Clearly, the worker's response was an overreaction — one that I'm sure was highly unexpected from President Hinckley. But instead of getting mad back — instead of angrily shouting, "I asked you to do this one thing and you're being a huge baby about it?" — he stepped back and simply laughed.
It allowed him to avoid a conflict and even helped the other man to realize that his own rage was unjustified.
It would have been really easy to be angry at [this member], but instead, we just chose to laugh about it. Life is a billion times more fun if you choose to laugh and let things go. The Lord has commanded us to forgive ALL men, and a big part of that is learning to let go; to not let yourself get so angry. I know from personal experience that letting things go and controlling your temper will make you so much happier and more positive than if you don't. The Lord has given us the commandment that we should forgive "70 times 7" as much for our benefit as for the person whom we forgive.
Being angry will not make you happy. The Lord doesn't want us to be unhappy and bitter. Choose a better way of life! I promise that if you ask the Lord to help you and then you diligently work at it, you can overcome your temper.
So learn to laugh! After all, life really is more fun that way.
We all know someone who, when angry, theoretically goes for the jugular. They find the thing you are most self-conscious about and they exploit it.
When you're mad, ask yourself, "Are the words I want to say going to help diffuse the situation or are they going to cause more damage?" When a tornado hits, the more damage is done, the more there is to clean up — and it's the same way when we say things out of anger. The more unkind you are, the more you have to clean up later… And cleaning up those kinds of messes is never enjoyable.
When I was a teenager, I remember my dad telling my sister and me that if we were mad, to count slowly to ten before we responded to someone. This trick really helped me, allowing me to air some steam and consider my words before I said them.
We can't control what life throws at us, but we can control how we react — and rather than reacting with anger, let us choose to react with love. Instead of spewing hateful words, let us soothe and comfort. Remember that our initial emotions may be negative, but we can always choose to respond positively.
I know with surety that the Lord will bless us for it.


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(1).P-acid degumming operation:Drawing the filtered or settled crude oil into the neutral pot, control oil te-mperature 40 ° C, liquid level cover the neutral pot volume about 80 %.Add into the neutral pot P-acid with 85% concentration, 0.1-0.2% oil weight.Start up neutral pot, make main shalf stirring at 60-70 r/min, finish de-gummingin 30 min.
when soap particles accumulated condensing, should reduce stirring speed, 30r/min avoid emulsion. After adding alkali, gradually rising temp to the end temp 65 ° C, see to that the rising temp speed should control at 1 degree per minute, not too fast. Shut off neutral pot drive part, the oil settled in the pot 6-8 hours, make oilseparate from soap.
shalf stirring washing at 30r/m-in, make the oil and water fully contact, stirring time 5-10 min.If oil/soap separat not ideal, the oil contains relative high left soap, the first time washing, better to use thin salt water evenly spray into oil.
de-color oil into the press filter, filter away waste clay, the last use air compressor blow clean and dry.
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After finish degumming process about Best seller in Africa Crude oil refinery plant,2016 best selling refining equipment,agricultural equipments for oil refinery, at once add into lye carrying alkali refining deacid, lye concentration 16 ° Be ′, super alkali is 0.1to0.3% oil weight, after finish adding, continuous stirring 30min, when soap particles accumulated condensing, should reduce stirring speed, 30r/min avoid emulsion. After adding alkali, gradually rising temp to the end temp 65 ° C, see to that the rising temp speed should control at 1 degree per minute, not too fast. Shut off neutral pot drive part, theoil settled in the pot 6-8 hours, make oilseparate from soap.


text:
Here's what a Bath homeless charity does for those without a place to stay at Christmas
For some it is not the most wonderful time of the year
Richard MillsBrighton & Hove Albion correspondent
Bath council says the amount of homeless people in the city is declining (Image: Getty)
Want to receive the latest top stories from around Bath straight to your inbox?
For many, Christmas is the most wonderful time of the year but for those living without a roof over their head it can be lonely and sometimes scary.
Homeless people in Bath, and across the UK, have to put up with heavy rain, strong winds, freezing temperatures and a dearth of food and drink all year round.
Homeless army veteran in Bath has not celebrated Christmas Day for 7 years
According to its website, Julian House was set up to offer direct support to some of the most marginalised people in society – the homeless.
Julian House has its own homeless hostel in Manvers Street (Image: Google Street View)
Initially this was limited to offering food and shelter.
Over time other projects and services have been developed which not only address the symptoms of homelessness but also the underlying reasons why men and women are forced onto the streets.
Homeless residents sleeping rough in 'small tented city' in Bath as multi-million-pound mansions sit vacant nearby
Further projects look to prevent people becoming homeless by engaging them in meaningful activities, training and preparation for employment.
Julian House's fundraising and PR director, Cecil Weir, has outlined what the charity will offer homeless people at Christmas.
A Christmas tree was donated to the charity by a supporter (Image: Julian House)
He said: "Julian House staff will be going out of their way to try and make the Christmas and New Year period as comfortable as possible for as many of its clients as possible and particularly at the Manvers St Hostel.
"This can be a very tough time for anyone who is homeless. It's really hammered home to them where they are in life and how disconnected they are from mainstream society.
"On Christmas Eve we'll be providing festive nibbles and doing board games.
Claims police want 'eyesore' homeless people off the streets during Bath Christmas market
"Then on Christmas Day there will be presents followed by a great lunch which is being provided by Bath Open Christmas.
"They have been doing this for Julian House for many many years and is a fantastic gesture of support for people who will be alone at Christmas.
"An amazing volunteer has kindly offered to come in on Boxing Day and lead on Christmas carols for the clients.
"Like the rest of society not all of our clients will want to be immersed in Christmas and of course we'll respect that. But for those who do it's only right that we try and make the period a bit special.
"Huge thanks to the volunteers who have given up their time to help. Likewise to the staff who will be making sure that we have a 24 hour service throughout.
How Taunton is tackling homelessness this week with a 'night cafe'
"It is also worth mentioning the medical team who will be on duty as well every day part from Christmas Day and New Year. And of course to the public for all their support."
To donate to Julian House, click here .
For the latest news and breaking news from Bath click here .
Follow us on Twitter @bathlive - our official news account.
We're also on facebook.com/Bathlive - your must-see news, features, videos and pictures throughout the day.
Get in touch by the channels above, email news@bathchron.co.uk or call 01225 322213.
Avon Fire and RescueBath fire crews tackle top-floor flat blaze in BathAn investigation showed the cause of the blaze was 'accidental ignition'
National Trust to protect Bathampton Meadows for future generations after park and ride threat
Bath and North East Somerset CouncilLand was owned by council and leader's father-in-law
Girl, 15, charged for assaulting emergency worker after 'noisy party' complaints
TrowbridgeSix police officers were assaulted after attending a noisy party
Unmissable ABBA-themed fancy dress brunch with bottomless drinks hits Bath
EntertainmentIt's time to dig out your most stylish 70s outfit and head to Revolution for an afternoon to remember

redpajama_set_name: RedPajamaCommonCrawl


Wigan made it three from three in the Super League with a 20 – 0 victory in the "Battle of the Borough" against Leigh Centurions at the DW Stadium on Friday night – the first league meeting between the two for 12 years.
Conditions massively effected the game, with handling errors from both teams being a consistent theme throughout the game. Wigan handed a debut to Liam Marshall on the wing, who despite a couple of handling errors, looked solid and looks set to get a good run in the team with Joe Burgess and Lewis Tierney leaving the pitch early with injuries. After the game, Shaun Wane confirmed that Burgess, Tierney and Ryan Sutton had all gone to hospital for scans – with the next game being a repeat of last years Grand Final against Warrington, a real concern for Wigan.
Wigan opened the scoring through Anthony Gelling, as we tipped in our preview (Match Preview) – we hope we made some of you some money! The try came from a great bit of play from Man of the Match, George Williams. A kick through the line saw Tierney skilfully keep the ball in play, by kicking the ball back in field, away from the Leigh defender – resulting in a simple pick up for Willie Isa, who could of scored himself. Isa, offloaded the ball to Gelling who crossed the line under the posts, Escare converting to make it 6-0.
The rest of the first half was marred by the injuries and the reshuffling of the team by Shaun Wane, which led to Isa and Joel Tomkins playing centre, with Marshall and Gelling on the wings. The tight affair, mainly due to the persistent rain had few chances, Escare missed a penalty goal attempt from 40 metres before O'Loughlin missed with a drop goal attempt (Yes, thats not a typo!) before Escare also missed with a field goal attempt.
In the second half, Tony Clubb was stopped inches from the try line, with many in the South Stand thinking he had scored. However his run created a gap in the defence which George Williams took advantage of with one of his trademark jinking runs to cross the line on the next play, Escare converted to make it 12-0.
Williams was involved in the third Wigan try of the game, a try that was very similar to the Luke Gale assist against Leeds on Thursday night that had the Sky commentary team waxing lyrical over. A break from Williams was followed with a superb kick with the outside of his boot to find Gelling in acres of space, another easy finish for Gelling for his second try of the game and the season. Escare converted to make it 18-0 to the Warriors.
The rest of the game was fought out through the middle in the tough conditions, Wigan's task made even harder by the fact that they only had one interchange player remaining due to the three injuries. The game saw one last flash point, with Gareth Hock giving away a penalty with a high shot on Frank-Paul Nuuausala; Escare adding the two points from the resulting penalty.
Despite George Williams winning the Man of the Match Award, its worth noting the role Morgan Escare had – another fine and impressive performance from the flying Frenchman and a great kicking display from him again. Wigan only signed him on a one year contract from Catalan Dragons – lets get that deal extended before they come back in for him.
All in all, job done by Wigan in difficult conditions and in particular due to the injuries picked up during the game. Next up, the Warrington Wolves at the Halliwell Jones on Thursday with Burgess, Tierney and Sutton potentially missing – plenty of opportunity for more of the Wigan academy graduates to get an opportunity.


Wolfe v. A-Med Health Care, Inc. [$140,000] | San Diego Sexual Harassment Attorneys, Sexual Harassment Lawyers in San Diego, CA.
Recovery: Hogue & Belong obtained a settlement of $140,000 against A-Med Health Care.
A-Med Health Care is a Specialty Pharmacy. It employs approximately 300 employees. A-Med Health Care also employs 8-10 Territory Managers at any one time to promote the services A-Med's pharmacy provides. A-Med classified the Territory Managers as "exempt" from the labor code.
The Territory Managers are assigned specific territories and visit various health care providers in those assigned territories to promote what A-Med offers in the hopes that these health care providers would start using and directing its patients to use A-Med's services. The Territory Managers passed out pre-approved marketing materials, and would have little knick-knacks to pass out during these visits. Also, Territory Managers would attend certain patient events, such as Cystic Fibrosis Walks to promote A-Med's services. The Territory Managers would pass out little sundries, like, for instance, water bottles with the A-Med logo on it.
Wolfe argued that the Territory Managers were "non-exempt" under the labor code and applicable wage statement. A-Med argued that they were exempt under the Outside Salesperson or the Administrative Exemption.
The Court certified the class action, and the case settled shortly thereafter.


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Home SPORTS Rohr considers new set of Eagles for World Cup
Rohr considers new set of Eagles for World Cup
Super Eagles' Technical Adviser, Gernot Rohr has not ruled out the possibilities of getting fresh legs for Nigeria, as he prepares the senior football national team for the June, 2018 FIFA World Cup in Russia.
The German coach believes with less than 150 days to the mundial he still has luxury of time to present sharp attackers, impressive midfielders, no nonsense defenders and dependable reserve bench.
As gathered, the German coach is already in Germany to monitor new players ahead of the international friendly matches against Serbia and Poland.
According to the Team's Media officer, Toyin Ibitoye, the former OGC Nice of France manager, who qualified Nigeria for the 2018 FIFA World Cup, has also been to France to speak with some of the players he intends to bring to the National team.
Toyin Ibitoye reported that Rohr was determined to present a strong team at the 2018 World Cup and he has been scouting around Europe to get the best players that will help him actualise his dream of excellent performances in Russia.
"Rohr is in Germany now monitoring players that could make his team for the upcoming international friendly matches that will help him get the best for the World Cup
He is determined to present a quality team in Russia and he has started monitoring the players he wants to give the opportunities to prove what they can do for Nigeria." Ibitoye said.
Leon Balogun and Anthony Ujah (both play for Mainz), and Wolfsburg's Victor Osimhen are some of the Nigerian players currently playing in the German Bundesliga.
"The list will be out soon but I'm sure around early March and that is why he is trying to move around now to see the players he is going to invite,.
Nigeria, who will face Iceland, Argentina, and Croatia in the first round of the FIFA World Cup in Russia, will play friendly matches with Poland in Warsaw on March 23 and Serbia in London on March 27.
Meanwhile, former Super Eagles striker, Julius Aghahowa has advised the Super Eagles World Cup hopefuls to stay fit ahead of the fast-approaching FIFA Mundial.
The former pacy forward, Aghahowa, on Brila FM, advised that it is important for the lads to stay 100% fit ahead of the tourney.
From my Korea/Japan World Cup experience, I think fitness is the essential thing and the players should try as much as possible to remain fit going to the World Cup," Aghahowa stated.
Julius played in Ukraine, England, and Turkey during his career representing Shakhtar Donetsk, Wigan Athletic, and Kayserispor.
Aghahowa played 32 matches and scored 14 goals for the Nigerian national team, including their only goal at the 2002 World Cup against Sweden.
He became Nigeria's top goal scorer at the 2002 African Nations Cup. He also played at the 2000 Summer Olympics in Sydney, Australia.
Jibril .O
Previous articleNigeria shines at Algeria badminton tourney
Next articleFIFA executive summit to hold in Lagos
Jibril Okehi


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Connecticut Post Homepage
Mobile van helps Bridgeport seniors register for COVID vaccine
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Bridgeport officials oppose application for housing complex
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Bridgeport ditches plan to move 66 students to Thomas Hooker
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Suspects in CT gas station break-in charged, police say
Former Bridgeport PD captain now Trumbull Zoning Enforcement Offi
Contamination complicates Bridgeport's sale of Sikorsky Airport
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John Mayer to headline Bridgeport's Sound On Sound music festival
Feb. 6, 2021 Updated: Feb. 6, 2021 8:37 p.m.
Carmine DiLeo, with Career Resources, listens to health care worker Stephanie Torres as she speaks for Harborview Apartments resident Mario George Olivera during a mobile COVID-19 vaccination sign-up site for seniors at the building in Bridgeport, Conn., on Friday Feb. 5, 2020. Career Resources converted the bus, borrowed from The WorkPlace nonprofit usually used for job training/recruitment, into the mobile sign-up site.
Christian Abraham / Hearst Connecticut MediaShow MoreShow Less
Krystyna Romano, with Career Resources, helps a Harborview Towers Apartments resident sign up for the COVID-19 vaccination during a mobile registration drive for seniors at the building in Bridgeport, Conn., on Friday Feb. 5, 2020. Career Resources converted the bus, borrowed from The WorkPlace nonprofit usually used for job training/recruitment, into the mobile sign-up site.
Career Resources converted a bus, borrowed from The WorkPlace nonprofit usually used for job training/recruitment, into a mobile COVID-19 vaccination sign-up site for seniors at the Harborview Towers Apartments in Bridgeport, Conn., on Friday Feb. 5, 2020. The idea is to provide elderly residents who may not have computers or internet access with the assistance needed to register/schedule their shots.
Krystyna Romano, with Career Resources, helps Harborview Towers Apartments residents sign up for the COVID-19 vaccination during a mobile registration drive for seniors at the building in Bridgeport, Conn., on Friday Feb. 5, 2020. Career Resources converted the bus, borrowed from The WorkPlace nonprofit usually used for job training/recruitment, into the mobile sign-up site.
BRIDGEPORT — More than two dozen people braved the cold, rainy weather this week to take advantage of the mobile COVID-19 registration van at Harborview Towers on East Washington Avenue in the city's East Side.
"This is very nice," said 77-year-old Stephen Geronimo as he finished registering for an appointment to get vaccinated. "It was very easy, and they were very accommodating."
Andres Vazquez, 66, was waiting his turn to get into the van. "I'm glad it's here," he said. "I don't know how I would have gotten a chance to put my name in to get the vaccine if it wasn't here."
Both men said they don't have access to a computer to register online and Vazquez, who said he recently suffered a fall and needs a walker to get around, said he isn't able to get to other sites to register.
The mobile classroom — typically used by Career Resources for job training and recruitment — was at the senior housing site to provide hands-on assistance to older residents seeking to use the federal Vaccine Administration Management System, or VAMS, to schedule an appointment for their COVID-19 vaccine.
A town-by-town map released by the state this week showed that cities, including Bridgeport, had low percentages of their populations vaccinated. In the state's largest city, 4 percent of its 144,399 population had received at least a first inoculation. The state's data also showed slightly more than 23 percent of the 6,914 people 75 and over in Bridgeport had received at least the first vaccination.
Carla Wright, service coordinator of the Bridgeport Housing Authority, which manages Harborview, said they had 30 people register to be vaccinated by 9:30 Friday morning.
"A lot of the elderly who live here do not have emails or are capable of using a computer, so we are helping them register," she said.
Wright said initially when they rolled up in the large van people at the elderly housing facility were reluctant to come out.
"Some still said they don't want to get a vaccine, others said they were going to go through their primary physicians," she said. "There are a couple of people in the building who have COVID and want to be vaccinated but can't come out because they are infected."
But once those who were initially reluctant saw other people coming out to the van, they came out too, she said.
Wright said they are taking the information on each senior and setting up an email account for each one on the vaccine registry website. Each senior is then given a slip of paper with their vaccine appointment date.
Councilwoman Maria Valle, who represents the East Side neighborhood, said she was excited to see the van there.
"This is awesome, last week I came here and picked up and elderly woman and took her to get vaccinated because she had no way to get out on her own," Valle said.
Councilwoman Aidee Nieves said it is going to take a massive effort to get seniors in the city registered to be vaccinated.
"This will be very helpful," she said of the van.
Harborview is operated by the Bridgeport Housing Authority, Park City Communities, whose low-income tenants, given their pre-existing health issues and service sector jobs, can be particularly vulnerable to COVID-19.
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The authority's executive director, Jillian Baldwin, said on Friday that the mobile van will be at another of her sites — Fireside senior apartments — on Feb. 11 or, if there is snow, Feb. 15.
"This brings the opportunity to their front doorstep," Baldwin said.
She said the authority is also looking at ways it can help transport tenants to vaccination sites.
"We're working to see if we can get buses or vans or supplement (public transportation) costs," she said, adding it would also be great if the city could find a way to provide vaccinations at public housing developments.
"We are absolutely open to that," Baldwin said. "That would be a wonderful opportunity for housing residents."
She said many are eager to receive their shots and the authority has been working to disseminate as much information as possible about the coronavirus vaccines in order to convince the skeptics.
"We definitely have some older residents, they (say), 'Cancer's been around for a while. There's no cure for that. How do we have the cure for this so quickly? There definitely is some trepidation and general distrust of the system."
Staff writer Brian Lockhart contributed to this report.
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text:
The Czech Republic, in Central Europe, is a country that's known for its ornate castles, native beers and long history. Prague, the capital, is home to grand 9th-century Prague Castle, a preserved medieval old town and statue-lined Charles Bridge. Český Krumlov, a small town in the South Bohemia region, is notable for its wealth of Gothic, Renaissance and Baroque buildings, many of which house restaurants and shops.
Capital: Prague
Dialing code: +420
Currency: Czech koruna
Official language: Czech
St. Vitus Cathedral | Czech Republic | Attractions
The Metropolitan Cathedral of Saints Vitus, Wenceslaus and Adalbert is a Roman Catholic metropolitan cathedral in Prague, the seat of the Archbishop of Prague.
Prague Capital of the Czech Republic | Czech Republic | Attractions
Prague, capital city of the Czech Republic, is bisected by the Vltava River. Nicknamed "the City of a Hundred Spires," it's known for its Old Town Square, the heart of its historic core, with colorful baroque buildings, Gothic churches and the medieval Astronomical Clock.
Krkonoše Mountain range in Europe | Czech Republic | Sightseeing
The Krkonoše or Karkonosze are a mountain range located in the north of the Czech Republic and the south-west of Poland, part of the Sudetes mountain system.
Kampa Island in the Vltava | Czech Republic | Sightseeing
Kampa is an island in the Vltava river in central Prague on the side of Malá Strana. Charles Bridge crosses its northern tip and is connected to the island by the street ulice Na Kampě.
Hluboká Castle | Czech Republic | Attractions
Hluboká Castle is a historic château situated in Hluboká nad Vltavou, and it is considered one of the most beautiful castles in the Czech Republic.


The filter is a pipe in a variety of pumps, valves, the main accessories. It applies to nominal pressure equal to or lower than 1.6Mpa, piping, mainly used for filtering steam, air, water and other medium to dirt, rust blocks and other debris.
Applicable medium: water, oil, steam, etc.


text:
Good Girl Gone Bad Live ist die erste Live-DVD/Blu-ray-Veröffentlichung von R&B-Sängerin Rihanna. Sie wurde zunächst am 13. Juni 2008 in Europa veröffentlicht. Die DVD beinhaltet die Show aus der MEN Arena in Manchester, England, während ihrer "Good Girl Gone Bad Tour" von dem 6. Dezember 2007. Diese DVD war für einen der 51. Grammy Awards für "Best Long Form Music Video" nominiert.

Inhalt

Konzert
 Intro
 "Pon de Replay"
 "Break It Off"
 "Let Me"
 "Rehab"
 "Breakin' Dishes"
 "Is This Love" (Bob Marley Cover)
 "Kisses Don't Lie"
 "Scratch"
 "SOS"
 "Good Girl Gone Bad"
 "Hate That I Love You"
 "Unfaithful"
 "Sell Me Candy"
 DJ Kevmo / "Don't Stop the Music"
 "Push Up on Me"
 "Shut Up and Drive"
 "Question Existing"
 "Umbrella"

Bonus Material
 "Dokumentarfilm" – Dies ist eine Dokumentation über die Reise der Good Girl Gone Bad Tour von November bis Dezember 2007. Rihanna spricht über ihre Outfits, die Setlist, die Band und die Bühne.
 "Hidden Video" – "Umbrella" selbstgemachtes Video von der Crew.

Veröffentlichung

Charts

Personal
Crew
 Anthony Randall (Production Manager)
 JP Firmin (Tour Manager)
 Mark Dawson (Security)
 Fankie Fuccile (Stage Manager)
 Alex MacLeod (Tour Accountant)
 Dave Berrera (Stage Tech)
 Alex Skowron (Lighting Director)
 TJ Thompson (Rigger)
 Simon James (Carpenter)
 David Kirkwood (Front-of-house Engineer)
 Richard Galercki (Monitor Engineer)
 Elizabeth Springer (Wardrobe)

Band
 Rihanna (Hauptsängerin)
 Kevin Hastings (Keyboard)
 Eric Smith (Bass)
 David Haddon (Schlagzeug)
 Adam Ross (Haupt Gitarrist)
 Richard Fortus (Gitarrist September 2008-February 2009)
 Ashleigh Haney (Background-Sängerin)
 Erica King (Background-Sängerin)

Tänzer
 Victoria Parsons (Kapitän)
 Rachel Markarian
 Bryan Tanaka
 Julius Law

Styling
 Ursula Stephen (Haare)
 Mylah Morales (Make-UP)
 Lysa Cooper (Stylist)
 Mariel Haenn (Stylist)
 Hollywood (Stylist)

Einzelnachweise

Rihanna-Album
Livealbum
Videoalbum
Album 2008

redpajama_set_name: RedPajamaWikipedia


Microsoft Project Server and SharePoint 2007 and 2010 June CU 2011 has now been released.
"If you are loading the June CU for 2010 we would also encourage you to load SP1 – see Announcing The Release Of Service Pack 1 (SP1) for Microsoft Project and Project Server 2010 for full details, and particularly the TechNet article – Deploy Service Pack 1 for Project Server 2010," notes Brian Smith for the Project team blog.
Installation of the client patch is straightforward and is the same as it was in Project 2007. The instructions for installing the client patch are below.
Download the hotfix from either the KB Article or by using the information at the end of this email.
Run the extracted .exe file to apply the patch to your Project Professional/Standard SP1 client.


That is how I generally refer to Pinterest, right along with my comments about how amazing it is. We use to avidly collect magazines and clippings of things that inspired us, which was no fun to go through when we decided to move out of our little house four years ago. It was actually kind of humorous trying to figure out what inspired us to buy the magazine in the first place and then hang onto it for years. The binders full of clippings seemed so dated, so irrelevant to our lives at that moment.
Whenever I look at websites like Pinterest I wonder how they generate money. How does Craigslist make money? A friend of mine answered that question for me recently and I was pretty amazed that this disruptive website, which destroyed newspaper classifieds and handicapped the financial wellbeing of local newspapers, is pretty bare bones.
Craigslist makes money only through a handful of revenue streams. It charges a $25 fee to post a job listing in six major U.S. cities. It charges $75 for a job listing in the San Francisco area. Last, the company charges a $10 fee to list an apartment rental in New York. The revenues generated from these fees cover only the operating expenses of Craigslist. The company has not made a profit since its inception. This is intentional -- Craigslist president Jim Buckmaster has stated that creating a superior user experience is more important to the company than making money.
This is relevant to me because of a business idea I've been playing around with, and it's interesting that Craiglist has chosen to only cover its operating expenses. At this point. Presumably, Jim Buckmaster has a board of directors and investors that he must answer to, and if they choose to pursue larger revenue streams, he might not have the leverage to prevent them.
Note the groovy fish scale pants. Nice.
The orange shoes are a perfect compliment to the large floral print. MiMBY Girl has a good eye.
Love the lace-up ballet slippers!


text:
EBA Assesses Risks in Banking Sector in European Economic Area
Regulatory Capital, Regulatory Reporting: EU, Systemic Risk
The European Banking Authority (EBA) published its annual risk assessment of the European banking system. The report is accompanied by the publication of the 2021 EU-wide transparency exercise data, in a comparable and accessible format, for 120 banks across the 25 European Economic Area/European Union (EEA/EU) countries. The report notes that banks as well as micro- and macro-prudential authorities need to be prepared in case of a deterioration in the economic outlook or in case inflationary pressure translates into further rising rates. Uncertainty on the economic outlook could trigger repricing of risks and increasing operational risks, mainly due to information technology and cyber risks, require banks to further priorities information technology and cyber-security.
Overall, the risk assessment shows improvements in EU banks' solvency, profitability, and liquidity, but asset price corrections remain a key threat. In the report, EBA notes that fiscal and regulatory support measures have not only prevented asset quality deterioration but have also made it more difficult for banks to assess borrower creditworthiness. The following are additional key findings of the risk assessment:
Banks' capital and liquidity positions have further improved. The average Common Equity Tier 1 (CET1) ratio has increased on the back of strong results in the first half of 2021. The positive mood in funding markets and the availability of central bank funding has allowed banks to maintain comfortable liquidity positions. Banks' net stable funding ratio (NSFR) reached on average of 130%, but analysis in the report shows that it would be significantly lower if central bank funding was excluded from the numerator. Although supervisory recommendations on capital distribution have expired, banks should not pursue overly generous dividend and share buy-back policies. Amidst increasing rate volatility, banks should carefully evaluate the risk profile of their funding plans and ensure they are able to substitute current central bank funding with other sources of funding.
Asset quality has improved overall but concerns remain for loans to specific sectors and those that have benefited from support measures. The non-performing loan (NPL) ratio has further decreased to 2.3% this year supported by several large NPL securitizations. However, the NPL ratio of the exposures to the sectors most affected by the pandemic is on an upward trend. The asset quality of loans under public guarantee schemes and under moratoria is a source of concern as an increasing share of these loans are being classified under stage 2 or as NPL. Accelerating house price increases along with banks' recent focus on mortgage lending may become a source of vulnerability going forward.
Operational risk losses have increased during the pandemic. The growing usage of and reliance on technology has been accompanied by a rising number and impact of information and communication technologies and security-related incidents.
Lower impairment costs have increased profitability, but structural challenges remain. Banks' net operating income has not recovered to pre-pandemic levels. The low and negative interest rate environment is still weighing on lending margins. This adds to high competition not only among banks, but also with fintech and bigtech companies. Despite the acceleration in branch closures during the pandemic, operating expenses have stabilized in the past year as pre-existing working arrangements have gradually resumed.
Banks have made some progress related to the environmental, social, and governance (ESG) risk considerations. The share of ESG bonds of total bank issuance has increased in recent years, reaching about 20% of banks' total placements this year. Banks have started integrating ESG risk considerations into their risk management. However, there is significant progress to be made, including in areas such as data, business strategies, governance arrangements, risk assessments, and monitoring.
EBA also published a factsheet on the European Centralized Infrastructure for Supervisory Data, also known as EUCLID, which is a platform for banking and financial data. Besides regulatory data, EUCLID collects a coherent set of master data information to identify institutions. Users can also find the list of institutions to which authorization has been granted to operate within the EU and EEA. It will increasingly facilitate the sharing and use of banking and financial data to external users, in a wide range of areas. In the factsheet, EBA notes that data on more than 2,500 EEA/EU investment firms and more than 300 EU/EEA investment firms' groups are expected to become available in EUCLID in 2022 while the resolution (planning, MREL decisions, MREL/TLAC) data on more than 2,400 EU/EEA payment institutions are expected to be available at end-2022.
Risk Assessment Report (PDF)
Transparency Exercise Data
Factsheet on EUCLID (PDF)
Keywords: Europe, EU, Banking, Basel, Regulatory Capital, Reporting, Systemic Risk, Credit Risk, NPLs, Operational Risk, EBA
Nick Jessop
Scenario modeling expert; risk management specialist; quantitative financial modeler
CBIRC Clarifies Derivatives Rules, Notes Progress in Bank Governance
European Council Aligns NIS2 Directive with DORA for Financial Sector


If you are looking for an excuse to bring the parties and care-free lifestyle of the roaring twenties back for one fabulous night, look no further than the Loyal Krewe of Grace O'Malley Gala taking place this Saturday. Get together your best flapper outfit and get ready for a swanky evening at the The Ritz Ybor in Tampa.
If you think 20s era music is the cat's pajamas and are looking to have a swinging good time, get your whole crew together for a fun night of dancing with music provided by an old-fashioned big band. Enjoy heavy hors d'oeuvres which will be served along with casino room activities, a cigar lounge and a live floor show! There is something for everyone at this year's gala.
The event takes place Saturday, Jan. 11, at 8 p.m. Speakeasy drinks will be served throughout the night at a cash bar, so come prepared! The Ritz Ybor is located at 1503 East 7th Ave. in Tampa. Proceeds from the night will benefit your local Make-A-Wish and tickets are only available for a limited time, so register today!
The evening promises to be a great time for everyone. It will also help to raise important funds that will help our partner, Make-A-Wish grant the wishes of local children with critical illnesses. Now is a great opportunity to help a worthy cause. Make-A-Wish Northern and Central Florida granted more than 285 wishes last year alone. Contributions from people like you makes granting wishes possible.
Wishes can take Wish Kids all around the globe and throughout the United States, to places like Albuquerque, Austin and Seattle. Each and every Wish Kid is unique, and so too are their wishes. What may seem like a small donation to you can make a huge difference in the life of a child. When you participate in this fun Gala, not only will you be getting fun new memories and a great experience, you will also feel great knowing that you have helped to make a child's dream come true!
If Make-A-Wish is an organization you support, but you don't have any desire to enjoy a night in the past, there are other ways to help Make-A-Wish achieve their goals. One way is by donating a car to Wheels For Wishes, an IRS registered 501(c)(3) nonprofit organization. Wheels For Wishes benefits Make-A-Wish and helps to turn your car into wishes for children with critical illnesses.
Making a donation is easy, so don't wait to donate! Car, truck, RV, SUV and even boats can be accepted through the nonprofit car donation program. We can take your vehicle whether it is running or not. Save some time and stress by donating your car today. Selling a car can be a hassle, and expensive. Making a car donation is free. Plus, your donation is 100 percent tax deductible! Just give us a call at 1-877-431-9474 or use our easy online donation form. We will pick-up or tow away your car for free from anywhere in Florida.


text:
Advice and the Advisor
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Why traditional investment strategies don't work
Traditional aggressive growth strategies no longer work, because they fail to take into account extreme volatility and the increasing frequency of bear markets.
Nearly 50 percent of the sales of S&P 500 companies originate outside the U.S — that's good for growth opportunities but exposes investors to more volatility.
In today's low-interest-rate environment, investors will be lucky to keep up with the rate of inflation.
Chris Cook, founder and CEO of Beacon Capital Management
Published 7:53 AM ET Tue, 22 Aug 2017 Updated 10:17 AM ET Tue, 29 Aug 2017 CNBC.com
Camerique/ClassicStock | Getty Images
Traditional aggressive growth strategies no longer work because they fail to take into account extreme volatility and the increasing frequency of bear markets.
Traditional investment strategies no longer work, and no single factor explains the failure of long-held investment tactics. Market volatility, global economic interdependence, emotional investing, inflation and a low-interest-rate environment all played a role in the demise of traditional investment strategies.
Let's take a closer look at each factor individually to better understand why the old methodology comes up short in this new market reality.
There's no way to sugarcoat it — market volatility is the new normal in today's investing environment. For decades millions of American investors have followed an aggressive growth strategy — a strategy that worked. For many it went like this: During those wealth accumulation years, invest heavily in equities such as blue-chip stocks. Rinse. Repeat. And for decades, as long as investors kept a long-term view, that formula worked.
Sure, there were bear markets to contend with (1966 to 1978 is one example), but they were bolstered by a more glacial pace. The markets moved with a more predictable upward or downward momentum, a fact no longer true in today's violent market swings. Those traditional aggressive growth strategies no longer work, because they fail to take into account extreme volatility and the increasing frequency of bear markets that leave investors, especially those closer to retirement, exposed.
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7 retirement-planning mistakes to avoid
How to avoid costly 401(k) rollover mistakes
7 ways to make sure you don't outlive your savings
Consider for a moment a typical American investor, age 60. We'll call him Dave. During his career, Dave worked and saved, but he's now thinking about retirement. After all, he's built a nest egg of a little more than $470,000, and he's getting close to his goal of retiring with $500,000 socked away. Even though Dave has already diversified and downshifted into a more conservative blend of equities and bonds, he could still hit his $500,000 target within a year with his projected growth of 8 percent returns.
But as with millions of American investors, Dave's success is closely tied to market timing. What if Dave's last year of work, that last year of looking to take a somewhat aggressive approach, occurred in 2000 or 2008? In that scenario, much of Dave's nest egg would be ravaged by bear markets. While those are the two biggest bears of this century, those massive swings are happening with increasing regularity, leaving investors who follow a traditional investment approach vulnerable to market volatility.
Global economic interdependence
In the traditional investment approach, an investor like Dave could put his assets in a mix of stocks, bonds, mutual funds, real estate or commodities. With limited volatility and steady growth, he was better protected than in today's marketplace. But there's another layer of volatility that Dave may not be aware of — the global, interdependent marketplace where the lines are blurred between domestic and international holdings. What were once distinct and separate holdings have become closely intertwined.
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At increasing levels, global interdependence has crept into almost every facet of a company's operations, including global sales, international sources of raw materials or services and offshore outsourcing, among others. In today's marketplace, nearly 50 percent of the sales of S&P 500 companies originate in countries outside of the United States, according to data compiled by S&P Dow Jones Indices. While that number is good for growth opportunities, it also exposes investors to more volatility.
Inflation and interest rates
According to the U.S. Bureau of Labor Statistics, the U.S. inflation rate stood at 1.6 percent year-on-year in June 2017. Historically, that's a drop for American consumers, as the inflation rate averaged 3.28 percent from 1914 until 2017. While the rate of inflation has been falling, it remains a cause for concern for investors like Dave, particularly due to the incredibly low-yield environment today's investors face.
If Dave were to get to retirement with his nest egg intact, he might have breathed a sigh of relief in the traditional investment world. He could have shifted much of his equity investments to certificates of deposit and Treasurys, keeping his market exposure low while he reaped a hefty double-digit return. Not so anymore. In the very low interest-rate environment of today, Dave will be lucky to keep up with the rate of inflation. In such a scenario, he might find himself tempted to return to market exposure in the chase for substantial yields.
Emotional investing
Emotional investing is hardwired into our DNA as humans. Dave is not immune to the tug and pull of the irrational behavior that accompanies emotional investing. But make no mistake — human emotions drive bad investment decisions. Picking an occasional winner only gives license to picking more stocks on whims and gut feelings, leading investors to an inevitable bad ending.
"A successful strategy today is one founded on a mechanical model that eliminates the desire for emotional investing, provides a stop-loss mechanism to limit losses and looks for investments across all 11 sectors."
How bad? I mentioned inflation in the previous section, but combined with emotional investing, the result is worse than you might imagine. A report by Dalbar revealed that the average portfolio's earnings have barely kept up with inflation, earning just 3.83 percent from 1992 to 2012. A mechanical model, such as seen with the S&P 500, delivered a 9.14 percent return in that same timeframe.
The traditional buy-and-hold investment models no longer work for investors like Dave. They no longer work for anyone who wants a healthy nest egg by the time they're ready for retirement. In today's volatile marketplace, retirement portfolios require investment strategies that seek growth opportunities while also offering protection against the frequent downsides.
A successful strategy today is one founded on a mechanical model that eliminates the desire for emotional investing, provides a stop-loss mechanism to limit losses and looks for investments across all 11 sectors. In short, it's one that sheds what no longer works and instead seeks reliable returns even amid this highly volatile, globally dependent marketplace.
(Editor's Note: This article originally appeared on Investopedia.com.)
— By Chris Cook, founder and CEO of Beacon Capital Management
WATCH: How Warren Buffett makes long-term investments
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How Warren Buffett makes long-term investments 10:23 AM ET Tue, 29 Aug 2017 | 00:58
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text:
package com.alibaba.fastjson;

/**
 * Beans that support customized output of JSON text shall implement this interface.
 *
 * @author wenshao[szujobs@hotmail.com]
 */
public interface JSONAware {

    /**
     * @return JSON text
     */
    String toJSONString();
}

redpajama_set_name: RedPajamaGithub


Social media addiction has been acknowledged as a formal condition in almost all parts of the world with treatment centers dealing with thousands of patients a year. The research has found that social networking features such as 'retweets' and "likes" give customers as increase of feel-good mind substances, while a lack of approval can cause rage and anxiety. Everyone who uses social networking websites needs to stop and think 'Am I getting something out of this and what am I efficiently causing the wealthy computer mediated lifestyles that we now lead?' Keeping in mind this fact, I have collected some photos for you.
My special collection of social media addiction photos belongs to the various people of all age groups – who are found here to be busy in surfing the social media websites in one way or the other. My top notch social media addiction photos make it easy to understand that how much these social networking websites have some long lasting effects on to our habits and lifestyle. Another common direction to job loss is the regular attraction that many workers have with social networking.
Suppose that if you said going on Facebook, Twitter and Pinterest over twenty times a day, then it does not intervene with your perform, you'd be relaxing. Some companies have taken actions to observe or restrict their employees' public networking use, while others have obstructed these sites completely. All these facts belonging to the harms of social media in different people become clear from the collection of mine. So, please have a look and enjoy photography. You also should observe that how the people are destroying their lives and their jobs by becoming addict to social media.


Management undermines you constantly. High turnover rate. Unclear objectives. High work load with no overtime offered. Social interaction is highly discouraged.
Lots of good people unfortunately they're working under inept management.
Practically a revolving door of employees, few people have been there more than 3 years.
The equity group that purchased the company will only be able to milk it until the customers get tired of faulty product delivered slowly.
Working for Colson was the most stressful experience I have ever dealt with. There are no processes in place, inventory is always wrong, and the turn over rate is increasing. HR does not address serious issues like bullying and inappropriate relationships. Before you decide to accept a job at Colson, ask them about the turn over rate. It will blow your mind. People are quitting right and left as well as getting fired. Some supervisors have had numerous complaints about being unprofessional and nothing has been done, instead those workers get fired and fed up and quit.
Colson is a growing company with lots of potential. Unfortunately, the turn over rate is incredibly high. Management has no integrity. Directors are having affairs with supervisors (who report directly to them). Favoritism is widely shown. HR does not address any of these issues. In addition to the lack of leadership and integrity they are so far behind on customer orders. Orders are being processed wrong and are past due 20+ days!!! Poor customers! Working at Colson has been a learning experience for things not to do. Although Colson is lacking integrity I still hope they can make a comeback because there a few hard workers that have been there for 10+ years. They deserve to work for a company they are proud of. I recommend giving a survey to all employees and taking action to their concerns and suggestions.
Company is poorly compartmentlized. Too many people have parts of different processes this has allowed poor communication and part flow to dictate work flow. Poor hirings in certain leadership positions has led to a high turn over rate.
At first I liked the job. But as time went by and seeing how people were fired over extremely little things, it became concerning. There is a point system so If you're late or call in sick you get points.
The hardest, working people the workers who go above and beyond there 8 hrs or push themselves to get customer orders pulled and out the door by 5pm are the ones who get let go because other employees lack the drive.
How can a company be customer driven with out being employee driven? Employees matter but to this company if you're a warm body that's all they want, If you think on your feet it's not what they want they want robots.
I was late and gave them over a week notice because my father was having triple by pass heart surgery, and I was still given a point and was told I had poor attendance.
Co workers will be nice to your face but will tell on you in a heart beat. DoNOT JOKE or try to fit in or be liked by your coworker because they lie and tell management on you.
If you have an outgoing personality STAY away from this place. If you have better ideas then a supervisor to do things STAY away from this place because they don't listen.
I am very disappointed with management and staff and human resources they have a policy about telling the truth and when you do you get fired and they lie to your face just days before.
There is no training or they will show you how to do something once and that's it. NO FORKLIFT DRIVER HAS A VALID LICENSE. If you have experience that is good enough.
Colson group is a high turn over rate. It is a very stressful environment because there are no processes in place. Most of the employees are uneducated and in positions that they are not qualified for.
Ask a question about working or interviewing at Colson Group. Our community is ready to answer.


text:
The planet has been so preoccupied with the pandemic that many of us forgot about the destructive effects of climate change.
Croix Ellison | Guest Commentary
The planet has spent so much time preoccupied with pandemic, for obvious reasons, that it seemed to forget all about climate change. As time moves on and more natural disasters in the form of droughts, heat waves, major floods, hurricanes and tornadoes in strange places reveal themselves, climate change will yet again strike our communities. One of its most deadly forms that we're dealing with right now: extreme heat waves. As Climate Central reports: "Recently, the mercury in Death Valley, Calif. climbed to a blistering 128℉ ーthe hottest temperature recorded on earth since 2017. Shortly after, NASA and NOAA announced that global temperatures from the first half of 2020 are the 2nd-hottest on record, just behind 2016. Greenhouse gas emissions are changing the chemistry of the atmosphere, causing our climate to warm to a level that modern society has never experienced."
While many communities were forced to stay-at-home as a precaution against coronavirus infection, we were all misled into a false sense of security about climate change. More people at home meant a major drop in commutes or reasons to go outside, use a car and travel to work. That led to a major drop in emissions, especially in major cities. Major modes of transportation responsible for spewing huge amounts of carbon emissions – which are behind human-made climate change – were dramatically limited in use. The skies above major cities turned from polluted haze to a remarkably clear plate of blue. However, as Rice University's Daniel Cohan observed: "The air is getting cleaner, although these blue skies may be temporary. But it isn't getting cooler. The buildup of greenhouse gas pollution continues, and global temperatures are still rising. You may have seen maps in the news showing blotches of air pollution that have shrunk since economies started shutting down in the past few months. Most of those maps are plotted from satellite observations of nitrogen dioxide, or NO2, a gas that triggers respiratory illnesses such as asthma. It also reacts in the air to form other types of pollution, such as smog, haze and acid rain. [But] what about carbon dioxide, or CO2, the leading cause of global warming? As we breathe cleaner air and see less haze, is that falling too? Unfortunately, no."
That will mean heat waves, which have been on the rise historically, are not going anywhere to the surprise and chagrin of many. The trend has been unstoppable since the 1960s (and coinciding with the rise in large scale manufacturing and fossil fuel use).
Scientists were already warning, as the pandemic continued that rising heat trends would continue into 2020, making it one of the hottest years on record.
As a result of these increasingly frequent heat waves, the nation will be facing additional health challenges, further complicating efforts to contain the pandemic. In the country's hope to transition out of COVID-19 (we emphasize hope because infections are still, as of this BEnote, still on the rise and are potentially reaching a tipping point where they may be uncontrollable), extreme heat will be especially difficult to shelter from this year. It will become a serious risk and will disproportionately threaten lower-income communities whose access to air conditioning is typically limited. Drexel University's School of Public Health epidemiologist Yvonne Michael offers perspective on this in a recent WHYY (Philadelphia) report: "Noticeably, the groups that are at higher risk for the increased illness and death associated with extreme heat are very similar to the groups that are at high risk for poor outcomes with COVID-19, with the exception of the young children."
Judging from the patterns of previous years, heat temperatures will continue to become hotter and longer. In addition, they will continue to manifest into a leading public health threat. In fact, heat waves are known to have caused more than 10,500 deaths in the U.S. between 2004 – 2018, according to the Centers for Disease Control and Prevention. All racial demographic groups are impacted, but as the table below shows, Indigenous Americans, Black Americans and Latinos – in this order – are the most disproportionately impacted.
Globally, researchers have estimated that there were 166,000 heat-related deaths worldwide between 1999-2017, which surpasses the death tolls of tornadoes, hurricanes, and floods.
From our heat patterns over just the past fifty years, extreme temperatures look much more dangerous today.
Although the meaning of "extreme heat" is defined differently in every city, temperature levels have still exceeded and increased across the entire nation. Furthermore, Greenhouse Gas emissions – such as methane, which accelerates the warming – are changing our planet's atmosphere, which is actively causing our Earth's global temperatures to change to concerning levels our society is not used to experiencing.
In recent years, many parts of the country, including cities hardest hit by heat waves, have made efforts and protocols to protect citizens from the consequences of extreme heat. However, for the past few months, there has been so much emphasis on coronavirus, particularly as governments on the local, state and federal levels face the worst revenue shortages since the Great Depression, that policy makers have yet to prepare for and are not equipped to deal with another record setting heat wave.
Over the course of the COVID-19 quarantine, our atmosphere experienced a dip in pollution and an improvement of the environment's air quality due to a decrease in carbon powered machines Fewer people are commuting all over the world. Traffic nowadays is limited to mostly essential trips, even as reopening happens. Some travel bans still restrict international flights. Canceled conferences, festivals, concerts and other public events have diminished tourism. Additionally, airline ridership has slumped altogether and airports are seen to be near empty. In China, a leading carbon emitter, experts estimated a 25 percent drop in carbon emissions.
Still, there is no way of taking back the emissions that have already been put into the air. As a result of the lack of effort to cut our carbon emission in previous years, there is no way to turn down our global thermostat back to the way it was naturally. Policymakers should, however, devise strategies now to reduce the impacts. That doesn't include rolling back key legacy environmental regulations. It means they will need to expand on them while reviving major provisions in global standards such as the Paris Climate Agreement. For now, with pandemic a priority, it's hard to predict when that will be prioritized.
CROIX ELLISON interns for the Council of State Governments Eastern Regional Conference Council on Communities of Color.
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infoecowurd


In Mitre's CVE dictionary: CVE-2016-4006, CVE-2016-4079, CVE-2016-4080, CVE-2016-4081, CVE-2016-4082, CVE-2016-4085.
Multiple vulnerabilities were discovered in the dissectors/parsers for PKTC, IAX2, GSM CBCH and NCP which could result in denial of service.
For the stable distribution (jessie), these problems have been fixed in version 1.12.1+g01b65bf-4+deb8u6.
For the testing distribution (stretch), these problems have been fixed in version 2.0.3+geed34f0-1.
For the unstable distribution (sid), these problems have been fixed in version 2.0.3+geed34f0-1.


Oprah Winfrey Show: ABC Television.
Mornings on Two: KTVU FOX Television Channel 2 - Oakland, California.
A View From the Bay: KGO Channel 7 - San Francisco, California.
Good Day Sacramento: CBS 13 / CW 31 - Sacramento, California.
The Morning Show with Mike and Juliet: FOX Television.
The Today Show: NBC Television.
KRON Weekend News: Channel 4 - San Francisco, California.
KFBK Newstalk Radio 1530 - Sacramento,California.
The Ronn Owens Show: KGO Newstalk Radio 810 - San Francisco, California.
The Rolonda Watts Show - Los Angeles, California.
The Morning Show: KWIN 97.7 & 98.3 FM - Stockton, California.
Jean Chatzky Show: Oprah & Friends - XM Satellite Radio channel 156.
Mark Dorenkamp Show: KGLO Newstalk Radio 1300 - Mason City, Iowa.
The Morning Show: WAFX Radio 106.9 - Norfolk, Virginia.
Evie's Talk Show: KKZZ 1400 AM - Ventura, California.


If you're obsessed by jewellery, you want to wear it all the time. But the more you wear it, the more you need to clean it. Soap, perfume, food, make-up, even skin oils—these come into contact with your jewellery every time you eat, wash, or just get ready for the day. Connoisseurs helps you maintain a jewellery care regimen that's essential to your beauty. No matter what the jewellery—from Pandora and Thomas Sabo to diamonds, from informal jewellery precious gemstones and luxury watches—Connoisseurs has the products that not only clean all kinds of jewellery, but also fit into your lifestyle. With products that are quick, convenient, and effective. Connoisseurs products clean oxidised silver and tarnished silver effortlessly. Not only are dirt and tarnish quickly removed, but an inviable barrier is also applied to delay new tarnish from forming. You wouldn't think of starting the day without proper skin care, and you wouldn't think of wearing clothes that need to be cleaned. Jewellery is no different. And Connoisseurs is the place to start.


Revolutionary Students Front (RSF) organized Two Days Marxist School on 12, 13 January at Mirpurkhas, Sindh. Despite heavy financial odds, difficult transportation, and deteriorating living conditions, more than 100 comrades from Karachi, Hyderabad and Dadu participated in this historic event. Most of the comrades including 15 female comrades reached Mirpurkhas by the evening of 11th January to attend the school with revolutionary spirit.
On the morning of 12th January, The School started by reciting revolutionary poetry, singing revolutionary songs and anthems. Nathu Mal, from the Hyderabad, welcomed all the participants. The first session on World and Pakistan Perspective was chaired by Lajwanti Tawar from Hyderabad and Hatim Khan from Karachi led the discussion. Hatim explained the overall economic crisis of the world and its social and political impacts. He explained the recent "Yellow Vest" movement that started from France and spread in the europe and beyond. He discussed the trade war between America and China. He explained the rise in the value of the dollar and the decline in the currency of Pakistan and other third world economies and the increasing debts. Devaluation of Pakistani Rupees will increase the inflation rates and subsequently decreasing the living standards of working people which are already in the worst state. The leadoff followed by questions and contributions. Lata, Pershotum, Jamun Das, Sadam, Akram, Rahul, Qarni and Anwar Panwar took part in the discussion and Majid from Dadu answered the questions and summed up the whole discussion on World and Pakistan Perspectives.
After the Lunch break, The Second session 'Socialism & Art' was conducted. Which was based on the newly published book by The Struggle Publications with the same title. The session was chaired by Sajjad Jamali while Rameez Misrani from Dadu led the discussion. The leadoff followed by questions and contributions. Imran Kumbhar, Ijaz, Saeed Khaskheli, Babar Panwar, Haji Shah and Imran Kamyana contibuted in the session while Kapil from Hyderabad answered the entire questions and summed up the whole discussion.
Marxist School 2019 at Mirpurkhas ended with raised fists and revolutionary slogans.
The second day of school, 13th January begins with reciting of revolutionary poems and songs by different comrades. The third session of the school was based on the "History of Student Politics and the role of RSF". The session was chaired by Saif Mandahar and the discussion was led by Munesh Dharani from Hyderabad. Munesh shed light on the History of students' politics. He also analysed the objective state pakistani youth and students specifically, also discussed the role of RSF and the strategy and tactics. He strongly stressed upon the work for the development of the student front, the "Revolutionary Students Front" (RSF). The leadoff was followed by regional youth work reports from Karachi, Hyderabad & Dadu. Afterwards, Jannat, Rahul and Qarni took part in open discussion. Nisar Chandio from the host region presented the school's finance report and Imran Kamyana concluded the school in his closing remarks. The school was historically marvellous. The culture, environment and mood were full of enthusiasm, energy and the revolutionary spirit. Marxist School at Mirpurkhas ended with Workers' Internationale anthem, raised fists and revolutionary slogans.


text:
The location: Yacht Club Restaurant
A. The Bay Terrace restaurant at the Cypress Harbor Yacht Club,
A. 11809 Raymar Street, in Miami.
A. In Episode 6, of Season 8, "A Little Reflection".
Dexter believes that young psychopath Zach Hamilton is about to kill a waitress, named Sofia, who works at his father's yacht club.
So Dexter heads down to the yacht club to head him off, and spots Zach waiting outside in a parked car.
Meanwhile, Dex sees Quinn, who is also following Zach. ( To get Quinn out of the way, Dexter phones Jamie and tells her she should invite Quinn over. That works. )
Dexter sees Sofia walk up a gangway, and then sees that Zach's father is with her. The two kiss, and Dexter realizes Mr. Hamilton is cheating on his wife again (his previous affair was with the murdered Norma Rivera).
Dex sees Zach get out of his car, carrying a large knife, and moves to intercept him.
But instead of trying to kill Norma, Zach instead is about to kill his father, when Dex suddenly appears and knocks Zach out with his needle.
Just then, Quinn pulls up in a car, and tells Dexter that he knows what he is doing. But Quinn only thinks that Dex is playing detective and following Zach.
Later, when he has Zach on his table, Dexter learns that Zach is killing to protect his mother, and takes Dr. Vogel's advice to become a mentor to Zach, rather than killing him.
A. A building at a marina, a smaller building nearby, a marina gangway, and the surrounding parking lot.
A. This building and parking lot are part of the Cabrillo Marina complex, in San Pedro, CA.
That complex is composed of multiple buildings, clustered around the large marina, many of them almost identical to one another: white, Spanish-style buildings with red-tile roofs.
The irony is that there actually is a yacht club at this marina, as well as restaurants, but they didn't use that actual yacht club building for the scene.
Instead, the building that you see, when Dex first arrives in his car - the one with the sign reading "Bay Terrace", where Quinn is waiting - is located at the east end of a street called Whalers Walk (which is more like a road inside of a parking lot).
To reach the building from the Cabrillo Plaza fountain (where they filmed the earlier bloody crime scene), you drive past the fountain and turn right (east) into the parking lot on Whalers Walk. Drive east to the very end of Whalers Walk, and it's the big, two-story building in front of you to your left. A large sign outside says 210 - Berth 31, and lists a number of yacht dealers.
They changed that sign to read "Bay Terrace" for the scene, used some color flood lights on the walls, and added a name banner to the second floor balcony.
There are several different locations in this scene - clustered in the same area: The restaurant building, the spot where Zach parks, the marina gangway where Zach's father enters with Sofia, the building Mr. Hamilton walks past when Zach was stalking him, and the spot where Dexter captures Zach with his hypodermic. (You can see the exact locations on this aerial photo map.
I shot the photos below in August 2013.
The first location is the yacht club / restaurant building: (The camera here is looking northeast)
The second is the marina gate (29-C) where Mr. Hamilton & Sophia walk up a gangway, then kiss.
It's the farthest gate to the east, on the south edge of the marina complex:
(The camera here is looking southeast)
The third location is the small, low building that Mr. Hamilton walks past, while Zach is stalking him.
It is just west of that gate 29-C. He was walking west as Zach stalked him:
(The camera here is looking east.)
And the fourth is the corner where Dexter captures Zach, moments before he would have killed his father.
Dexter sprang out from the building's southeast corner, that you see marked by the red X.
(In this photo, the camera here is looking south, towards the marina slips.)
Here is an aerial photo of the locations. Here is a Bing Streetside View.
And here is a map link.
A. They filmed the earlier crime scene (with Zach) here at the Cabrillo Marina, so it was obvious that this night scene was also shot somewhere in that same marina complex. The only problem was pinpointing which buildings they used, since many of them tend to look alike.
Fortunately, this particular building (the one used as the yacht club restaurant) has a unique flower-shaped keyhole window on its west side, which is visible as Dexter drives past the yacht club at the start of the scene.
So it was just a matter of using aerial photos to look at the various buildings until I found the one with the window that matched. There is no Google StreetView on Whalers Walk, but fortunately there is Bing's StreetSide View, and that allowed me to get a great look at the building. And then I drove down there to verify it, and to shoot the photos you see above.
All other photos & text are Copyright © 2020-Gary Wayne and may not be used without written permission.


Have you ever wanted to be a fansubber and create your own subtitles for anime or jdrama? Usually it is a very labor intensive process with timing, or tough actually finding an inexpensive video editing program with the feature. Well the people at DivXLand have created a new, free program called DivXLand Media Subtitler that makes it very easy. Currently it supports over 30 different subtitle formats and 15 popular video formats. Check out more information at their website.


First of all, although I am currently working on an institute that primarily focuses on oncology, I am not really oncologists myself. My original profession was actually a "craft" = neurosurgery whose success lies, in addition to specific theoretical knowledge, on manual labor. For almost ten years after my injury to radiation surgery (radiation neurosurgery), I co-got the "oncology" oncology, but I still find myself in the oncology issue as a very layman. However, because the urgency of my wife's illness forced me to search for "solution" as quickly as possible, "surf" the Internet and if I find something interesting there, I try to intuitively separate "weed". One of the means I have not yet hinted at is also the wife of a daily spoonful of hotly prepared blends of maple syrup and edible soda. There are a few things I do not "fit", but on the other hand, I feel that consuming the mixture should not "go wrong". The source from which I drew, I attach. In addition to adjusting the pH (and mixtures of maple syrup / soda), I have also come across other "guaranteed" types of cancer, and I am, for example, amygdalin. So I also include another of my information sources, where other methods are taken over. If you ever write to me what you think about them, they certainly will not be offended.
Note that I ( in my previous answer ) avoided the criticism of maple syrup / sap, but I have just added blueberries, birch sap, and Inonotus obliquus . Maple sap is not without effect and may help a bit against tumors ( Legault2010aai ). The "Bicarbonate Maple Cancer Treatment" document you sent me for review is just a pile of pseudoscience fantasies, and the effectiveness or ineffectiveness of maple syrup actually does not say anything at all. You probably feel yourself, and I confirm.
Amygdalin is a simple molecule that is nothing but a source of cyanide. It serves to avoid eating apricot seeds but discarding and leaving other apricots to grow. Of course, the idea is that we can selectively poison the cancer cells by cyanide. But this is not possible because cyanide has the ability to selectively kill only some cells at all. The mitochondria, which they eliminate, are backed up by glycolysis. The cyanide kills the whole body with a global lack of energy. This is exactly the same situation as it is not possible to starve a certain undesirable village by blowing up a local supermarket because the villagers bring food from around. Until the overall shortage of food in the state would be effective, but we do not want it.
Any attempts to use more glucose, energy, etc. in the fight against cancer cells, because they have higher metabolism, are useless because they do not differ fundamentally from healthy cells in this respect. The brain, the heart, the kidneys, the liver, the brain, the heart, the kidneys, the liver ... The charlatans around these treatments are perpetuum mobile inventors: stubborn, often themselves victims of their tough ideas, but with the advantage of often finding desperate patients willing fantasy to share and finance. Pharmaceutical empires are also scolding.
The concept of attack on cancer cells over its high metabolism is weak, scientifically unacceptable. It's like trying to hit the moon with a stone. This is theoretically possible, but practically not. If the Little Prince's asteroid had a magnitude of magnitude similar to the size of the Little Prince, the Little Prince would have the chance to enjoy stunts in addition to watching the sunrise. But the idea of throwing stones from Earth to the Moon is, as you know, pointless. We are able to judge this intuitively because we have practical experience with stones. Such a plan would not be sold to us. But when we move from the world of stones to the world of molecules, we are no longer sure whether cancer cells can or can not be destroyed by feeding a source of cyanide. Maybe I've spent much of the space here in the streaming of the stones, but I'm demonstrating that even nonsense can be written in a mundane way. And that's my comment on the second document you sent about amygdalin and laetrile, incorrectly called "vitamin B 17 ".
If you do not want to surrender to the will of fate, and all you want to do is touch the moon, I have a tip for you: Combine this trastuzumab with an alpha emitter. Compared to plain trastuzumab, it would have the advantage that those neighboring cancer cells that are not expressing the HER2 receptor would be affected. Such a conjugate is not commonly sold, so it is either to be ordered from one hand or manufactured separately. This is not easy, but unlike amygdalin treatment, this is not entirely impossible. So if you want to spend it.
Go to the library and borrow Bioconjugate Techniques . You will find page 783, chapter "Antibody Modification and Conjugation", and you will see the corner. You sit down behind the keyboard to find out which cells in the body, under physiological conditions, express the HER2 receptor and at what concentrations. You will concentrate on the three most important populations of these cells. For them, do you want to solve this problem: What can be the maximum concentration of the alpha emitter with a short half-life in a given tissue to survive 90% of the cells at its complete disintegration? The three concentrations of α-emitters that come out in this way will be divided by three concentrations of HER2 receptors in the given tissues and you will select the smallest of the three concentrations. This number should not be too small, certainly not much smaller than 1, but it should not be too large.
In the next step, select the appropriate radionuclide. It should be a pure alpha emitter with a short half-life. The shorter half-life is better from the therapeutic point of view, but again, such isotopes are less well manipulated. For example, radium 223 ( 223 Ra, Nilsson2005fce ) has a half-life of 12 days and is almost pure a radiator: 223 Ra - α (12 days) => 219 Rn - α (instantly) => 211 Pb - β (30 minutes) => 211 Bi - a immediately => 207 Tl - β (instantaneous) => 208 Pb (stable). You have four wounds α (β not count, you are extra) so the number you have previously calculated is divided by four. The result will give you the number of radio atoms 223 that you need to attach to each molecule of HER2 of the antibody (trastazumab). To select another radionuclide, the number of particles may be different. According to Dadachova2010ctw , for example, bismuth 212 ( 212 Bi), bismuth 213 ( 213 Bi), actinium 211 ( 211 Ac) can be considered as well.
Book the Bioconjugate Technique book where the bend is curved and select a suitable method to capture the calculated number of nucleotide atoms per trastazumab molecule. If there are too many, you have to make a tassel. But so many of them may not be. Order the required linkers, under the aegis of an authorized Nuclear Laboratory, which is certainly not far from your workplace, order the selected radionuclide, stuff it in the test tube with the antibody, mix well, let it react, clean the column from unreacted liners, uncontaminated nuclides and other trash, in physiological saline and you can drink. Do not forget to eat ginseng to reduce radiation damage to normal cells.
Then describe your success to Current Radiopharmaceuticals, whose No. 3 of September 2008 was just a method of targeting a radiological attack on HER2-positive cells dedicated to and confirming the effectiveness of this strategy, find it there. Here, in Sweden ( Tolmachev2007rth ), those HER2 antibodies again tested adhesive luteum 177 ( 177 Lu). Otherwise, somebody gets rich on the radio (they call it Alpharadin, Liepe2009a2a ), but it's unlikely that your patient cared for you to stick it to trastuzumab because of her, they could go to jail.
It takes only a few days to absorb new knowledge and to find out how to respond to them. However, I would be wondering if the pure alpha-emitter linked to trastuzumab should be applied multiple times or only once. Trastuzumab should be infused for 3 weeks until the baseline progression. I see this as a problem because the cavaly catheter has been canceled (the wife has completed 6 cycles of chemotherapy) has been aborted, for the increased extremity vulnerability of the upper limb on the mastectomy / axenal side of the axilla should not be given any infusion, the vessels of the opposite the side has a "miserable" + environment, where it should. treatment with trastuzumab, I find it problematic even from a psychologist. aspect.
Tastuzumab works by targeting the target cells to destruction by the immune system of the host. Another mechanism of action may be that the cells adhering to the surface on the surface will interfere with the growth of the adherent antibody. In any case, this antibody restricts / kills only those cells that HER2 is carrying on their surface. Not far from all. Finally, in the event of unsuccessful trastuzumab therapy, it becomes lawful that cancer cells learn HER2 to not express and help without it.
The advantage of targeted radiotherapy would be that radiation would hit a range of hundreds of microns around HER2 clusters expressing cells. However, you have come across a major problem that I completely neglected in my half-serious manual, and that is dosing. For the correct dose, it would be necessary to accurately estimate the amount of expressed HER2 receptors in the body, and the antibody combined with the alpha emitter would ideally be given in stoichiometric amounts. It would be ideal to give it exactly one-time dose and calculate the radiation dose exactly so that the radionuclide completely fired cells underlying the mitosis around HER2-positive tissue and did not completely destroy the tissues expressing HER2 naturally. Doing it almost twice makes no sense, because if it does not destroy the cancer cells for the first time, then in the second attempt, the survivors will be more. It's like spending cockroaches - once and for all.
In addition to HER2, it would be especially advantageous to find other receptor-specific receptors for which a more potent cytotoxic therapy could be used. But this is not realistic in this case. We can continue to communicate by phone.