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Commercial & Creative Writing»
The Search for Amy: A Short Story by cam
Chris has written more than 200 flash fiction/short stories. Working Vacation was 21st out of 6,700 in the 2016 Writer's Digest competition.
Rick and Rodney rode into the barn one morning while Tom was putting the bridle on his Welsh Pony/Appaloosa cross named Wendy.
"You can stay on your ponies, cause we gotta go look for a lost cow," said Tom.
"Which one's lost?" said ten year old Rodney as he sat on Ginger, his Shetland Pony.
"Amy," said Tom. "Dad was gonna put her in the box stall today to have her calf, but now she's missin."
"Where we gonna look first," said thirteen year old Rick, astride his white Appaloosa gelding named Billy.
"The pastures on both sides of the creek.Then we'll check the woods."
"What if we don't find her?" said Rodney.
"We'll probly have to walk the cornfields," said Tom.
"That's a lot of walkin," said Rick.
"Maybe we'll find her before that. C'mon, let's ride," said Tom.
Pipe Creek ran through the property owned by Tom's Mom and Dad. At some time in the past its limestone bed had been blasted out with dynamite. The result was a strip of limestone rubble piled along the creek. Some of these hills had been covered by blowing soil and sported a healthy growth of grass. In the woods, where the hills were protected from the wind, bare limestone mounds lined the creek.
Out in the open pasture, the boys rode their ponies up and down over the grass covered hills along the creek as they searched for Amy. At the end of the pasture, which was also the end of the property, the boys crossed the creek and searched the other side as they rode back toward the barns. That's when they discovered the dead tree that had fallen and landed on the fence.
"It's a good thing the cows don't come back here on this side of the creek very often or we'd be lookin for the whole herd," said Tom.
"Do you think Amy got out here?" said Rodney.
"If she was lookin for a quiet place to have her calf, she might have wandered back here and gotten out. She could be anywhere now," said Tom.
"Looks like we''re gonna be walkin through cornfields the rest of the day," said Rick.
"And tomorrow," said Tom.
The boys reported the fallen tree and the mashed down fence to Tom's Dad, Carl. The farmer's big hand reached immediately for the telephone.
Within a few minutes, Carl and the boys were in the car heading to town, after a brief stop at Rick and Rodney's house. They needed to ask permission to go up in a small airplane with Carl and Tom to look for the lost cow.
A red Mooney M20C Ranger sat outside the hanger at the Municipal Airport with a full tank of fuel. The boys raced to the single engine aircraft to see which of them would get to sit in the front seat next to Carl who would be piloting the plane. In the end, though, Carl placed the boys where he wanted them in order to have the correct weight distribution. Rick was the biggest of the three, so he sat in the front, next to Carl. Tom was in the seat behind Rick, and Rodney sat behind Carl.
Mooney M20C Ranger
Out on the runway, the pavement blurred as the plane raced ahead, bumping and bouncing, until the wheels left the ground and all they felt was the smoothness of floating on air. While they were flying toward the farm, Rick asked a question.
"If Amy is gonna have her calf, why not just let her have it wherever she is? She'd come back on her own after that, wouldn't she?"
"I'm sure she would," said Carl. "But there are two medical conditions that might occur while Amy is giving birth, and either one could cause her and the baby to die."
"One's milk fever, right Dad?" said Tom.
"That's right, son."
"What's milk fever?" said Rodney. "Does she get hot like I do when I get the flu?"
"No, Rodney," said Carl. "The word fever is misleading in this case. Her temperature would actually go down. Milk fever occurs when the cow's calcium level drops as a result of producing a sudden, large quantity of milk in preparation for the birth of the calf. Calcium helps muscles work properly. If it dropped too low, the cow would be forced to lie down, unable to get up again. The newborn calf couldn't eat and both would likely die without the help of our veterinarian, Doc Lamkin."
The boys became more anxious after that explanation, watching out the windows for the first sign of the farm.
Mooney M20C Takeoff
"Tom, why don't you explain the other thing that could happen to Amy and her calf," said Carl.
"Oh, that would be a breach birth," said Tom. "Sometimes the calf can get turned around inside its mother. It's supposed to come out nose and front feet first. If it's trying to come out wrong, somebody has to reach inside and turn the calf around so it can get out."
"Reach inside?" said Rodney. "Yuk, that is so gross."
"It's not so bad," said Carl. "The person doing it has a long plastic glove on that reaches to his shoulder."
"Shoulder?" said Rodney. "They stick their arm in all the….." Rodney began acting like he was vomiting on the floor.
The Farm Today With Pipe Creek to the Left of the Barns
"Hey, there's the farm," said Tom, pointing further west. The plane flew over the farm buildings, the tin roof of the big red barn glowing in the sunlight like a the lens of a giant spotlight.
"The first field we'll check is the eighty acres near where you found the tree across the fence," said Carl. The plane began flying north and south, back and forth, low enough for the search team to see between the six foot tall stalks of corn. It wasn't a perfect view, but it was their best chance at finding the cow.
"I hope she's standing up when we find her," said Rick.
"I hope the calf is already born," said Rodney.
"I hope you both get your wish," said Carl.
About an hour later, Carl pulled the plane up and turned toward the barns. Clouds were forming in the western sky and they still had not found Amy.
"We may have time to search the next field, but then we've got to get back to the airport," said Carl. A forty acre cornfield stretched out before them with an alfalfa patch adjacent to it, leading right up the to the first row of corn.
"She's gotta be down there," said Tom. "We searched everywhere else."
Twenty minutes later, Carl turned the plane to make the final pass over the field. The man and the boys were silent, wondering what to do next. At the end of the field, Carl pulled the plane up and began a slow turn toward the east in the direction of the airport.
"There she is," shouted Rodney. "And she's layin' down, too."
The boys heard Carl let out a low groan of disappointment.
"I see the calf," said Rick.
Carl turned the plane back toward the corner of the field. Amy had made a small circle near the edge of the field by mashing down cornstalks. He flew low over the cow and calf, hoping to be able to tell if Amy was sick or well. He finally pulled the nose of the plane up again.
"She's up," shouted Rick. "And so is the calf."
"Thank God," said Carl.
"Yeah," said Rick and Tom.
"Amen," said Rodney.
Carl landed the plane back at the airport just minutes ahead of the storm. They drove back to the farm through a driving rain with thunder and lightning alternating, offering a dramatic audiovisual display. Inside the barn, the boys bridled the ponies and hopped onto their bare backs as Carl gave them instructions.
"You'll have to walk the ponies back so Amy can keep up. Cover the calf with this." Tom took the rolled up sheet of plastic and spurred Wendy out into the storm with Rick and Rodney close behind.
They tied the ponies to the fence at the end of the alfalfa field. Amy would already be nervous because of the thunder and lightning, so they crept cautiously toward the corn. As they weaved their way through the rows, pollen from the tassels mixed with the rain and landed on their hats and shirts.
They stopped two rows from Amy's clearing. The calf was nursing and the boys waited patiently. When the calf was finished, they stepped into the circle. Tom spoke quietly, taking slow, deliberate steps. Even though Amy was a pet, she might get aggressive if they moved too quickly. But the cow trusted the boys, allowing them to pet her and her calf.
"Is it a boy or a girl?" said Rodney.
"Can't you tell?" said Rick.
"Sure I can. I just don't want to, that's all," said Rodney.
"It's a heifer," said Tom.
"That means it's a girl," said Rick.
"I know what heifer means," said Rodney. "I'm just glad it's a girl cause the boys always disappear."
"Yeah," said Rick. "They disappear into the freezer."
"The freezer?" Said Rodney.
"Never mind," said Rick.
Tom dropped down onto one knee while Rick and Rodney lifted the calf and draped it over his shoulders, legs dangling against his chest. They walked back toward the barn leading the ponies, with Amy following close behind. Tom's Dad was waiting in the box stall where he had put down fresh bedding. He lifted the calf from Tom's shoulders and placed it gently onto the dry straw. Amy began licking the calf, making sure all was as it should be.
That night the boys slept in the hayloft. They lay in the darkness listening to the rain as it drummed on the tin roof.
"Rodney," said Rick. "It's a good thing the calf wasn't breach. You might have had to reach in and straighten it out."
"Aw, Rick. Why'd you hafta say that right when I'm tryin to fall asleep?"
Later, as Tom and Rick continued to listen to the night's sounds, they heard Rodney mumbling in his sleep, saying something about his arm and being stuck. The next morning, Rodney woke with two long plastic gloves covering each arm, all the way up to his shoulders.
Rodney to the Rescue: A Short Story By cam, Part Two (of2)
by Chris Mills19
The Last Corn Game: A Short Story by cam
Catch That Pigeon: A Short Story by cam
Short Stories about Christmas Romance
by Colleen Swan17
Memories of Dunkirk: a short story by cam
Some Change is Not Welcomed: Billybuc Photo Challenge
by Rodric Anthony4
Coming Home: My Response to Billybuc's Photo Challenge
by John Hansen37
Before Closing
by Richard Tyler0
William Leverne Smith
3 years ago from Hollister, MO
Oh, my. Thank you, so much. I always get drawn in by a horse photo. Then, I get to enjoy the story! ;-)
Deb Hirt
4 years ago from Stillwater, OK
Excellent work. I was riveted and enjoyed everything about this story.
4 years ago from Green Bay, Wisconsin...for now
Eric, Now that's good feedback. Thanks for stopping by and for leaving such an encouraging comment.
Eric Dierker
4 years ago from Spring Valley, CA. U.S.A.
Great story. I feel like I know those boys. Fun indeed.
Thanks for the wonderful comment MsDora. It's nice to see you here on my hub today.
Dora Weithers
4 years ago from The Caribbean
You add details that make the reader say your story must be real. Your characters are adorable--children and animals. I like the conversations and the happy ending too.
Genna, thank you for that positive, encouraging feedback. It's nice to have you visit my hub.
Shauna, one of our calves got the name Bright Eyes. I should have thought to put that in the story.
Genna East
4 years ago from Massachusetts, USA
Chris, this is indeed a charmer -- and so well-written. I look forward to reading more. :-)
Venkatachari M, I'm glad you found it interesting and humorous. Thanks for reading and commenting.
Ruby, I'm glad you enjoyed this one. Thanks for stopping by.
Blossom, It sounds like you and I were on the same adventure. Sorry about the dance dress. Thanks for reading.
Larry, glad you enjoyed it.
Venkatachari M
4 years ago from Hyderabad, India
Very interesting and humorous. Enjoyed a lot. Thanks for it.
Ruby Jean Richert
4 years ago from Southern Illinois
Cute story and glad it was a happy ending. The long gloves gave the tale a look at the boy's sweet innocence. Another great story!
Bronwen Scott-Branagan
4 years ago from Victoria, Australia
Lovely story. It reminded me of when I stayed on a friend's farm as a teenager. It was pouring with rain, too, and we had just come back from a dance, but had to find the cow and calf. Lucky we did, they were right next to a rising creek and she had milk fever. I had to carry the calf back to the barn - you should have seen my dance dress!
Larry Rankin
4 years ago from Oklahoma
I Love stories with a rural backdrop.
Great hub!
Thanks Ann, I remember going to school the next day and asking those who lived near our farm if they saw a small red plane fly over. Some did remember, and I was so proud to tell them it was us. Nice to see you today, Ann. Have a treat weekend.
Ann Carr
4 years ago from SW England
So glad it was a happy ending. I love the camaraderie between these boys; basing stories on fact makes it so much more believeable though not necessarily easier to write. You, however, create such easy reading, conjuring up the places and people perfectly.
The plane and the aerial photos are great. I've once been up in a similar plane with my Dad piloting - the only time I enjoyed flying!
Great story well told, Chris.
Becky, I'm glad you enjoy these stories. I didn't dress this one up too much with fiction. It's pretty close to how it happened. It's a simple story with a happy ending.
Becky Katz
4 years ago from Hereford, AZ
Cute story. I always enjoy reading about these three boys and living on the farm.


This motion features a subtle chevron pattern spread across the whole golden yellow background. A grungy texture moves around the image adding subtle movement. The warm hues help set a peaceful serene feeling. There is plenty of room for adding your own text or images. This is a gorgeous background to help set a calm meditative mood for any setting and is a great background for fall or Thanksgiving! The Thanksgiving Prayer 3 Motion Background is part of the Thanksgiving Prayer Collection.


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About Immunology
Durham and the Triangle
Duke Integrity
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Herbert Kim Lyerly, MD
George Barth Geller Distinguished Professor
Campus Mail: 203 Research Drive, Rm 433B, Box 2606, Durham, NC 27710
Email: lyerl001@mc.duke.edu
M.D., University of California at Los Angeles, 1983
Selected Grants and Awards
Enabling effective anti-tumor immunity from targeted antibodies through dual innate and adaptive immune checkpoint blockade in non-immunogenic cancers
Duke University Program in Environmental Health
Viral Oncology Training Grant
Determinants of geographic disparities in mortality and multimorbidity in the U.S.
Defining the Rules of Breast Cancer Cell Traffic Through Bone
Developing a HER3 Vaccine to Prevent Resistance to Endocrine Therapy
Translational Research in Surgical Oncology
Transfusion Medicine and Hematology
Mechanisms of Action and Resistance to PD-1 Immunotherapies in Breast Cancer
A Molecular Framework for Understanding DCIS
Oncogenic Signaling Networks
Establishing the molecular and cellular mechanisms of Lgr5 signaling for controlling cancer stem cell behavior
Immunotherapeutic Targeting of a Therapy Resistant Oncogenic HER2 Isoform
Investigating Adaptive Immune Recognition of Dormant Disseminated Tumor Cells
UNC - Duke Immunotherapy Training Program
Inhibition of Wnt/B-Catenin Signaling in Colorectal Cancer Therapy
3D Biology Signatures defined by Nanostring Max System
Duke-Komen Fundamentals Training for Patient Advocates - AAADV
A Cancer Rainbow Mouse for Simultaneous Assessment of Multiple Oncogenes
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Advancing Immunology in Dogs with Naturally-occurring Invasive Bladder Cancer, a Relevant Model to Improve Immunotherapy Across Molecular Cancer Subtypes in Humans
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Immunotherapy with High Frequency, CEA Specific
SPORE in Breast Cancer
Cancer Center Core Grant Supplement - Accelerating Anticancer Agent Dev Workshop
Targeting hCG-beta for Breast Cancer Immunotherapy
Developing Biomarker-Based Prognostics in Breast Cancer
Vaccination with Regulatory T Cell Depletion
Markers of short term breast cancer risk in FNA
Novel Biomarkers for Aromatase Inhibitor Therapy
Phase II trial of Cetuximab & Carboplatin in Basal-like Breast Cancer
Biomarker Studies for Novel Anti-Cancer Agents
Dendritic Cell Based Immunotherapy
Immunotherapy using peptide MHC tetramer isolated Tcells
Dendritic Cell Mobilization and Active Immunotherapy
Immunologic Correlates of Effective Immunizations for Cancer Vaccines
Planning a Duke Academic Public Private Partnership Program (AP4) Center
Phase II Trial of Estradiol Therapy for Advanced Breast Cancer
Mentored Oriented Research Career Development Award
Cancer Center Core Grant - CURE Supplment
Immunotherapy of Prostate Cancer with Tumor Vaccines
RNA Transfected Dendritic Cells for Cancer Immunotherapy
Dexasome Based Immunotherapy of Lung Cancer
Immunotherapy with TRICOM Modified Dendritic Cells
Cytomation MoFlo High Performance Flow Cytometer
Dendritic Cell Immunotherapy For Breast Cancer
Cancer Immunotherapy With Rna Pulsed Dendritic Cells
Immunotherapy With Peptide Pulsed Dendritic Cell
Immunotherapy With Peptide Pulsed Dendritic Cells
Viral Control And Immune Reconstitution In Hiv Infection
Viral Control & Immune Reconstitution In Hiv Infection
Immunotherapy Of Breast Cance5 With Gene Modified Tumor
Immunotherapy Of Breast Cancer With Gene Modified Tumor
Immunotherapy of Breast Cancer with Gene Modifier Tumor
DUMC Aids Malignancy Program
Surrogate Markers Of Tumor Specific Immunity
Preclinical Development Of Rna Decoys
Adoptive Immunotherapy For Aids Lymphoma
Cellular Immunity Against Post-Transplant Lymphoma
Morse, Michael A., Smita K. Nair, Paul J. Mosca, Amy C. Hobeika, Timothy M. Clay, Yuping Deng, David Boczkowski, et al. "Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA.." Cancer Invest 21, no. 3 (June 2003): 341–49. https://doi.org/10.1081/cnv-120018224.
Morse, Michael A., Timothy M. Clay, Kirsten Colling, Amy Hobeika, Ken Grabstein, Martin A. Cheever, and H Kim Lyerly. "HER2 dendritic cell vaccines.." Clin Breast Cancer 3 Suppl 4 (February 2003): S164–72. https://doi.org/10.3816/cbc.2003.s.007.
Mosca, Paul J., Amy C. Hobeika, Kirsten Colling, Timothy M. Clay, Elaine K. Thomas, Dania Caron, H Kim Lyerly, and Michael A. Morse. "Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand.." J Leukoc Biol 72, no. 3 (September 2002): 546–53.
Morse, Michael A., David Rizzieri, Timothy T. Stenzel, Amy C. Hobeika, James J. Vredenburgh, Nelson J. Chao, Timothy M. Clay, Paul J. Mosca, and H Kim Lyerly. "Dendritic cell recovery following nonmyeloablative allogeneic stem cell transplants.." J Hematother Stem Cell Res 11, no. 4 (August 2002): 659–68. https://doi.org/10.1089/15258160260194802.
Morse, Michael A., and H Kim Lyerly. "DNA and RNA modified dendritic cell vaccines.." World J Surg 26, no. 7 (July 2002): 819–25. https://doi.org/10.1007/s00268-002-4058-0.
Clay, Timothy M., Michael Morse, and H Kim Lyerly. "Redirecting cytotoxic T lymphocyte responses with T-cell receptor transgenes.." Expert Opin Biol Ther 2, no. 4 (April 2002): 353–60. https://doi.org/10.1517/14712598.2.4.353.
Morse, Michael A., Timothy M. Clay, and H Kim Lyerly. "Current status of adoptive immunotherapy of malignancies.." Expert Opin Biol Ther 2, no. 3 (March 2002): 237–47. https://doi.org/10.1517/14712598.2.3.237.
Keilholz, Ulrich, Jeffrey Weber, James H. Finke, Dmitry I. Gabrilovich, W Martin Kast, Mary L. Disis, John M. Kirkwood, et al. "Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy.." J Immunother 25, no. 2 (March 2002): 97–138. https://doi.org/10.1097/00002371-200203000-00001.
Morse, Michael A., Smita K. Nair, David Boczkowski, Douglas Tyler, Herbert I. Hurwitz, Alan Proia, Timothy M. Clay, Jeffrey Schlom, Eli Gilboa, and H Kim Lyerly. "The feasibility and safety of immunotherapy with dendritic cells loaded with CEA mRNA following neoadjuvant chemoradiotherapy and resection of pancreatic cancer.." Int J Gastrointest Cancer 32, no. 1 (2002): 1–6. https://doi.org/10.1385/IJGC:32:1:1.
Morse, M. A., S. Nair, M. Fernandez-Casal, Y. Deng, M. St Peter, R. Williams, A. Hobeika, et al. "Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer.." J Clin Oncol 18, no. 23 (December 1, 2000): 3883–93. https://doi.org/10.1200/JCO.2000.18.23.3883.
Mosca, P. J., A. C. Hobeika, T. M. Clay, S. K. Nair, E. K. Thomas, M. A. Morse, and H. K. Lyerly. "A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-gamma treatment.." Blood 96, no. 10 (November 15, 2000): 3499–3504.
Li, Y., M. Bendandi, Y. Deng, C. Dunbar, N. Munshi, S. Jagannath, L. W. Kwak, and H. K. Lyerly. "Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells.." Blood 96, no. 8 (October 15, 2000): 2828–33.
Lyerly, H. K., T. Clay, and M. A. Morse. "Optimizing dendritic cell function by genetic modification.." J Natl Cancer Inst 92, no. 15 (August 2, 2000): 1198–99. https://doi.org/10.1093/jnci/92.15.1198.
Markert, M. L., C. B. Hicks, J. A. Bartlett, J. L. Harmon, L. P. Hale, M. L. Greenberg, G. Ferrari, et al. "Effect of highly active antiretroviral therapy and thymic transplantation on immunoreconstitution in HIV infection.." Aids Res Hum Retroviruses 16, no. 5 (March 20, 2000): 403–13. https://doi.org/10.1089/088922200309061.
Boczkowski, D., S. K. Nair, J. H. Nam, H. K. Lyerly, and E. Gilboa. "Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells.." Cancer Res 60, no. 4 (February 15, 2000): 1028–34.
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redpajama_set_name: RedPajamaCommonCrawl


text:
Palmarès

Olimpiadi
  a  nel K1 10000 metri.

Collegamenti esterni

redpajama_set_name: RedPajamaWikipedia


text:
import { Component, OnInit } from '@angular/core';
import { Router} from '@angular/router';
import { JobOffer } from '../job-offer';
import { JobOffersService } from '../job-offers.service';
import { SearchPipe } from "../../shared/pipes/search.pipe";

@Component({
    selector: 'sd-home',
    templateUrl: 'app/+job-offers/list/job-offers.component.html',
    styleUrls: ['app/+job-offers/list/job-offers.component.css'],
    providers: [JobOffersService],
    pipes: [SearchPipe]
})
export class JobOffersComponent implements OnInit {

    jobOffers: JobOffer[];
    jobOffersSearchValue: String = "";

    error: any;

    constructor(
        private router: Router,
        private jobOfferService: JobOffersService) { }

    ngOnInit() {
        this.getJobOffers();
    }

    getJobOffers() {
        this.jobOfferService
            .getJobOffers()
            .then(jobOffers => this.jobOffers = jobOffers)
            .catch(error => this.error = error); // TODO: Display error message
    }

    gotoNewJobOffer() {
        this.router.navigate(['/job-offers/new']);
    }
}

redpajama_set_name: RedPajamaGithub


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MAWRTH VALLIIS by EPHK is an original pocket-sized Martian-language graphic novel from Image
A pocket-sized sci-fi graphic novel is coming our way from Image Comics this July – Mawrth Valliis, by EPHK. This 128-page Martian-language original graphic novel will arrive in comic shops July 21 and bookshops July 27.
The plot of the book is as follows:
"During a skirmish with an opposing Martian faction, a fighter pilot disobeys orders to pursue a fleeing foe. Guided by her determination and curiosity, she is led into a dangerous chase through Mars's forbidden valley where she will be confronted with the red planet's darkest of secrets."
EPHK is elusive artist Electric Pick. Not much can be gleaned about them but their Instagram profile describes them as a 'Doodler/Comic Artist/Publisher/Honourable correspondent', and currently based in Berlin. They have also been making and selling books for about a decade from three different countries. At a glance at their blog, they may also be a tattoo artist. EPHK currently has a Patreon "dedicated to the process and creation of my Magda Gamma sci-fi adult graphic novel series and all of my NSFW comics and artwork." Curiouser and curiouser.
Mawrth Valliis was originally a Kickstarter project that ran in November last year. It had an €8000 (about $9500) funding goal, and made €11,334 — 140% of its target.
On the Kickstarter page, EPHK described how the comic came about:
"I'm not gonna lie… It's a bit trippy. This project is… let's call it "conceptual" and born from many very different influences hitting me at a very specific time. It is very different from what I usually do but it was so much fun to make and I am so damn proud of how it came out.
It all came together when my new found love for the format of 70's Mexican Historietas (smaller size/few panels per page) merged with my desire to make a very classic 70s style sci-fi short story. It contains a lot of the things that I always want to do in comics but that never really fit with other stories I am working on.
I also, for the first time, decided to render everything digitally (in my own very analogue way). I usually hand paint my pages and this was a big change for me (I really thought it would be faster… I was very wrong). And what was initially supposed to be a month long, 32 page short project eventually mutated into a 5 month, 128 page brick. And the result is 100% awesome guaranteed!"
And if you don't have a Martian translator to hand, don't worry –
"it is paced as a silent comic so if you don't read Martian you won't actually be missing anything."
The preview pages are definitely intriguing, one must admit. Look for the book in stores in July.
A Year of Free Comics: Everything is definitely not fine in EVERYTHING IS FINE
INTERVIEW: Anna Kendrick & Daniel Dae Kim tease STOWAWAY on Netflix


Piche Decor is a Unclassified business in East Grand Forks, MN.
Piche Decor, a stable growing company under Unclassified, is being run by Deborah Piche, Owner Full Name Report. Since , their sales have been favorable and consistent at $100.000 to $499.999. Company location coordinates are: 47.947414,-97.035263.
It can be reached by dialing (218) 773-7380 Full Phone Report, and you could get in touch with their sales team in 2137 11th Avenue Nw, East Grand Forks, Minnesota MN 56721. Visit their website at: to know more about the company's history, products and services, as well as frequently asked questions and privacy policies.
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July 14, 2016 Exclusive
Wishberry, a Crowdfunding organisation, has managed to gather phenomenal crowdfunding support for artists belonging to the LGBTQ community or people creating something for the community. Since 2013, it has managed to organize 11 LGBTQ Crowdfunding campaigns, raising an amount of about Rs. 24 Lacs, with a hundred percent success rate, meaning all of the campaigns have met their targets.
The idea of crowdfunding came about when Priyanka's ex-McKinsey colleague Anshulika Dubey discussed with her the prospect of running a crowdfunding platform for the creative sector. At that time, Anshulika was working on a McKinsey report on social media and crowdfunding, where she learnt about the concept and the successes it had in the West.
Priyanka then convinced Anshulika to leave her job and join her to lead creative crowdfunding within Wishberry. The two founders spent the year 2012, researching whether to focus on the creative sector or social sector or both. They tested these two models on their beta product. During this time, they learnt several crucial lessons that would go on to shape Wishberry in its present form.
Lessons such as, the All or Nothing model of crowdfunding was not only important, but also the most successful. This was because it built backers' trust and campaigners' accountability. They also learnt that certain sectors were more amenable to rewards based crowdfunding, as projects like films and music couldn't really turn to conventional modes of funding like a Venture Capital. Rewards based crowdfunding was the best way for these kinds of projects. During mid-2013, they decided to focus only on the creative sector and built their technology and branding accordingly.
Anshullika of Wishberry
Now, Wishberry has moved beyond just a portal. They observed that, inspite of having a great idea, these artists were finding it difficult to sell it and attract funders. Hence, they expanded into being a crowdfunding agency, wherein they guide and provide consultancy to creative artists on the marketing and communications front, along with technology support to track the response to their project in detail.
Since 2011, Wishberry has raised around INR 8 crores from more than 300 projects. They have a success rate of 70%, which is the highest in the industry, in terms of projects achieving 100% or more of their target crowdfunding amount.
Anshulika, talking about Wishberry's work with the community says, "Our first LGBTQ campaign was Kashish in 2013, which was a great success. Following this success, Kashish continued to use Wishberry to crowdfund for three more consecutive years along with 7 other artists belonging to or creating something for the LGBTQ community. In total, we have had 11 LGBTQ campaigns since 2013, which have managed to raise more than INR 24 lacs."
Art by or for the LGBTQ community has been existing for hundreds or maybe even thousands of years. However, it is still in its nascent stage in terms of gaining its share of popularity, and Wishberry has not just helped these artists raise funds, but also create awareness about LGBTQ issues. "For us, as a crowdfunding platform having the privilege to host such artists, the experience has been fascinating. We have come across some amazingly unique and innovative ideas which bring the entire community together. Their crowdfunding effort not only got them sufficient funds to bring their idea to life but also, served as a platform to create awareness and measure the acceptance of their idea prior to the launch," she adds.
Apart from Kashish, two other projects with an amazing storyline that were able to successfully raise funds were The Other Love Story – a web series on two young girls who end up falling helplessly in love and Hyacinth – a dance drama on same sex love by Sandip Soparrkar.
Sridhar Rangayan, National Award Winning Director and one of the Organisers of Kashish Festival, says, "KASHISH Mumbai International Queer Film Festival was the first LGBT initiative ever to use crowdfunding as a means to support the festival. Since 2012, KASHISH has crowdfunded on Wishberry successfully for the past 5 years. Though crowdfunding is only a part of the total funding that is required to organize the festival, it forms an important component as it involves the KASHISH audience and those who believe in the mission of the festival."
Sridhar points out that crowdfunding gives the contributors a sense of being personally associated with the project, and they become stakeholders in the project and actively publicise it too. "Through their contribution they feel that it is their own festival that they are supporting in some way. KASHISH offers exciting rewards like T-shirts, DVDs, Opening Night invites, reserved seating, etc. But people contribute not for the rewards, but for the belief they have in the vision and mission of the festival. The contributors also share and publicise the event, helping in the festival's outreach."
Sridhar also adds, "What is important about crowdfunding is that the campaigner remains engaged with the contributors and ensure not only that the rewards are delivered, but also that the communication and engagement continue. After the contributors have placed their trust and faith in your project and it is upto you to maintain that faith and deliver." However, he warns against campiagners who break the trust of people by abandoning their projects fater raising funds. "Crowdfunding campaigners who disappear once their campaign has ended bring a bad reputation and mistrust. There was a LGBT film that made a lot of noise and many promises, but the filmmaker abandoned the project after the campaign. Now that is definitely not a done thing. We ensure that our contributors and supporters continue their trust and faith in us by delivering b0th on rewards and also a film festival that lives upto its reputation, of being South Asia's biggest LGBT film festival, and one of world's top 5 coolest LGBT film festival."
Kashish has raised funds via Wishberry
Another interesting aspect of the crowdfunding campaigns comes through an exciting observation where 25 percent of the crowdfunders remain anonymous to the artists, highlighting a support system building up that is not just made up of friends, but also the society as a whole. Such support system indicates a growingly aware society which is aiming for artistic independence.
Kashish has been crowdfunding via Wishberry, and Sridhar is all praise for the team and their commitment to LGBT issues and campaigns. "The team at Wishberry has been extremely passionate about every campaign and ensure to make it a successful one by their intrinsic involvement in managing and promoting the campaign. There is transparency and honesty in managing the campaigns and to maximize its results. This year, part of the money raised through crowdfunding, helped KASHISH offer scholarship to filmmakers to bring them to the festival to interact with audiences. It also helped us pay a small honorarium to all the brilliant volunteers who make the festival as beautiful and friendly as it is. In fact, this year, Wishberry furthered their commitment to LGBT cause by coming on board as Title for KASHISH 2016. This was a huge support in ensuring that the festival can scale up its edition, reaching out to a larger audience and hence creating greater awareness through the medium of cinema."
We wish Wishberry a very best of luck so that they may continue with their organizational support for the community, and also thank the kind funders, who have been giving events of such brilliant potential a support system to work upon!
Sayantan Datta
Sayantan is an active LGBTQ expressionist who slays down the stereotypes, trying to change the world one sequin at a time
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Computers silently switched to 2000 in country after anxious country today, but the dreaded Y2K bug's first bite was barely felt.
Japan reported the failure of a computer linked to radiation monitoring devices at a nuclear power plant, but said it wasn't considered serious enough to shut the facility. In Spain, minor Y2K glitches at two nuclear plants were quickly fixed.
Experts said many Year 2000 computer troubles still might take days or weeks to develop. But as the new year was completing its victory lap around the globe, crossing into the United States without a stumble, the prevailing feeling about Y2K was one of anticlimax.
From time zone to time zone, as computers contended with the date change from 1999 to 2000, the story was the same. Cash machines kept working in New Zealand, the lights stayed on in India, planes landed safely in China, telephones still rang across the Middle East - and everywhere else.
In Russia, much of which still runs on clumsy Soviet-era technology, officials reported no problems at nuclear weapons sites or at any of the country's 29 nuclear reactors. Aging atomic power plants also ran without a hitch in Ukraine, which in 1986 suffered the world's worst nuclear disaster with a meltdown in Chernobyl.
Western Europe and Africa also seemed to sail into 2000 without incident. No problems were seen in Angola, Uganda and Kenya, where the telephone system was said to be functioning as erratically as usual. Italy, one of the worst-prepared countries in the West, also appeared to cross into the new century without any major trouble.
Many countries suffered brief disruptions in phone service, blamed not on Y2K but on the surge of midnight calls by people to family and friends. Cell phone service was slow on Rio de Janeiro's Copacabana beach because of high demand, but no Y2K-related problems were reported in Brazil.
A critical milestone for worldwide air travel passed without incident at midnight Greenwich Mean Time in Britain. GMT, also known as Universal Coordinated Time and "Zulu" time, is the global standard used to track planes as they cross time zones.
The widespread expectation that computers would fail in many nations was based largely on anecdotal information because "we didn't know what technology was there," said Matt Hotle, research director at the technology consulting firm Gartner Group.
Among the scattered Y2K glitches that did crop up, a provincial court in South Korea issued automated summonses to 170 people to appear for trial on Jan. 4, 1900 instead of Jan. 4, 2000.
Elsewhere, ticketing machines on some buses in Australia briefly jammed. Forecasting maps at the French weather service initially displayed the New Year Day date as "01/01/19100."
In the United States, the Federal Aviation Administration reported momentary problems with printers in transoceanic air traffic control centers in New York, California and Alaska. An electric utility in Wisconsin suffered a Y2K-related glitch when its clocks jumped ahead 35 days, but there was no interruption in power. At least one other unidentified plant experienced a similar problem.
"Literally, you can count the number of Y2K-related calls we've received around the world on one hand," said Don Jones, head of Y2K troubleshooting for Microsoft.
Communications, transport, defense and power systems continued to function normally.
Despite the seemingly smooth transition around the world, experts said it wasn't time yet to totally drop your guard.
"We do expect to see glitches, headaches, hiccups in the systems that support business, some of the accounting and billing systems, so these will create inconveniences next week," Bruce McConnell, director of the International Y2K Cooperation Center, said in Washington.


No one knows how it got there, but there it is: chewing gum on your favourite jumper. Carefully, you try to brush it off, but – ah – it's stuck. You're in a sticky situation, but there's no need to panic. With a little luck and the right technique, removing chewing gum can actually be fairly easy.
The steps below should help you remove chewing gum from clothes, even if they are delicate and require gentle handling. Just remember to read the labels on your clothes and any cleaning products before you start.
First, make sure that the gum has hardened. To speed things up, you could try using two ice cubes to harden both sides of the gum. You may want to wear gloves while holding the ice in place (it will be cold!) or put the garment in a plastic bag in the freezer for a couple of hours.
Now that the gum has hardened, the chewing gum removal process will be a bit easier. Start to gently peel it away from the material. Extra care is needed here if you're dealing with a delicate fabric – avoid catching any of the fibres, especially on knitted or embroidered items, and don't pull too hard.
Top tip: If you're struggling to peel the gum away with your fingers, use a spoon to ease the gum from the fabric, taking care not to damage the material beneath.
Heat can help you lift off any small pieces of gum that are still stuck to tiny threads or fibres. Use a hair dryer on a medium heat to warm up the gum. Take care not to overheat the fabric, especially if you are dealing with a delicate material like silk.
If the chewing gum is still there, try soaking the area in some lemon juice or vinegar, or spraying it with hairspray, before wiping away any gum remnants. These chewing gum removal methods should be used with caution on delicate fabrics, so it's best to test your chosen chewing gum remover on a small area of the fabric first.
Finish by washing the garment as you usually would. If you are dealing with a delicate fabric, use a non-bio detergent that is specially designed for washing delicates, like Persil Silk & Wool. Always follow the washing instructions on the garment care tag.
Chewing gum removal can be as easy as that – no specialist or expensive chewing gum removers required!


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Jeffrey M. Reid
Home – Team Member – Business Formation, Mergers & Acquisitions – Jeffrey M. Reid
Home – Attorneys – Jeffrey M. Reid
Mr. Reid began his association with McCormick Barstow in 1984. When not serving in government posts he has maintained a diverse transactions practice, concentrating in real property, land use, and California Environmental Quality Act (CEQA) compliance matters, including litigation defending land use entitlements.
jeff.reid@mccormickbarstow.com
McCormick Barstow Voted Best Law Firm In The Central Valley For The Eighth Year In A Row
McCormick Barstow Fresno is Hiring!
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He also has experience in matters concerning mitigation fee act compliance and regional transportation financing. Mr. Reid has represented both developers and governmental agencies in complex land use planning/CEQA matters at the administrative, trial court and appellate levels. He has an extensive knowledge of land use planning documents and zoning ordinances throughout the Central Valley, and has represented clients in land use matters in Fresno, Kern, Madera, Mariposa, Merced and Monterey counties.
Mr. Reid has served as the city manager for the City of Fresno, where he was responsible for the operational oversight of all facets of municipal government, including planning and development, utilities operations, public works projects, and industrial and economic development affairs. Mr. Reid has also served as Undersecretary of the California Business, Transportation and Housing Agency. In that capacity he supervised thirteen departments of California government. Departments within the Agency included Corporations, Real Estate, Caltrans, and Housing and Community Development. Mr. Reid also served as a member of the Fresno County Assessment Appeals Board and as a member of the San Francisco Bay Conservation and Development Commission.
Mr. Reid is admitted to practice in Virginia, California, the District of Columbia, the United States Supreme Court, and the United States District Court for the Eastern District of California.
Juris Doctor, 1984
Bachelor of Arts, Economics and Political Science, 1981 cum laude
Concentrating in Land Use Planning/CEQA Matters, Real Estate Development, Commercial and Real Estate Financing and Environmental Law.
Mr. Reid is a member of the Virginia State Bar; State Bar of California; District of Columbia Bar and the United States Supreme Court Bar Association. Mr. Reid has previously served on the Fresno Council of Governments Policy Advisory Committee (1997-2000); Executive Board, Economic Development Corporation Serving Fresno County (1997-2000); Governor's Water Policy Council (1993-1996); San Francisco Bay Conservation and Development Commission (1993-1996); Fresno County Assessment Appeals Board (1992-1993); Fresno County Bar Association and the Fresno County Bar Real Estate Round Table Steering Committee.
Mr. Reid is AV Preeminent® Peer Review Rated with Martindale-Hubbell. He was selected for inclusion in the Northern California Super Lawyers list (2012-2021) for his primary practice area in Land Use/Zoning.


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Cybersecurity: NY Adopts Final Regulations for Banks, Insurance Businesses and Other Financial Services Institutions
Mayer Brown
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USA March 21 2017
On February 16, 2017, the New York State Department of Financial Services ("NYDFS") finalized regulations that mandate cybersecurity standards for all institutions authorized by NYDFS to operate in New York, including many banks, insurance entities and insurance professionals doing business in New York.1 The final regulations, titled "Cybersecurity Requirements for Financial Services Companies" ("Final Regulations"), implement a significantly revised version of the NYDFS's September 13, 2016, proposal. (See our September 22, 2016, Legal Update for an analysis of the original proposal.) The Final Regulations became effective on March 1, 2017 ("Effective Date"), but there is a phase-in period as described below. In addition, the NYDFS issued frequently asked questions with corresponding answers on March 13, 2017 (the "FAQs").2 The intent of the Final Regulations is to "require effective cybersecurity to protect consumers" and NYDFS-regulated institutions. Acknowledging that the "number of cyber events has been steadily increasing and estimates of potential risk to our financial services industry are stark," the Final Regulations explicitly state that cybersecurity is a "priority for New York State." The Final Regulations are quite comprehensive and address everything from access controls and encryption to data disposal and employee training. We expect they will have significant ramifications not only for large institutions but also many medium-sized institutions that have only limited operations in New York and are already staggering under the post-financial crisis regulatory burden. Despite expanded exemptions, the Final Regulations will cover many small institutions and impose significant new compliance costs. This Legal Update (i) describes the relevant definitions and institutions affected by the Final Regulations, (ii) explains their substantive requirements and (iii) highlights some of the takeaways for the financial services industry. I. Definitions and Scope Covered Entity: The Final Regulations apply to any person operating under or required to operate under a license, registration, charter, certificate, permit, accreditation or similar authorization under the New York Banking, Insurance, or Financial Services Laws. This definition is intended to be broad, and indeed, many institutions are evaluating if they fall within the scope of the Final Regulations. On the banking side, although it is clear that banks and trust companies that are formed under New York law are within the scope of the Final Regulations, it remains to be seen how NYDFS will apply the Final Regulations to institutions that have no physical presence in New York (e.g., non-New York banks that are registered as exempt mortgage servicers), institutions with minimal operations (e.g., loan production offices) and non-New York 2 Mayer Brown | Cybersecurity: NY Adopts Final Regulations for Banks, Insurance Businesses and Other Financial Services Institutions institutions whose New York presence is not operationally separate (e.g., non-New York state banks that have domestic branches registered with NYDFS). Additionally, the FAQs confirm that non-US institutions will need to apply the rule to Covered Entities that are technically registered or authorized by NYDFS but may not have their own information systems or possess customer data that is segregated from their home offices (e.g., New York branches, agencies and representative offices of non-US banks). The FAQs indicate that such a Covered Entity should apply the Final Regulations only to information systems that support its operations and Nonpublic Information (defined below) that belongs to it. On the insurance side, Covered Entities include not only insurance companies (regardless of domicile) that are licensed to do business in New York but also other types of business entities and individual professionals (again, regardless of domicile) that are licensed under the New York Insurance Law, such as insurance agents and brokers, insurance adjusters and reinsurance intermediaries. Nonpublic Information: Nonpublic Information is defined as any electronic information that is not publicly available and that is (i) business-related information, the unauthorized disclosure or destruction of which would cause a material adverse impact on the Covered Entity; (ii) information concerning an individual that could be combined with specified data elements to identify the individual; or (iii) derived from an individual or healthcare provider and related to certain healthcare information (except for age and gender). Cybersecurity Event: Cybersecurity Event is defined as any act or attempt, successful or unsuccessful, to gain unauthorized access to, disrupt or misuse an information system or information stored on such a system. Third Party Service Provider: Third Party Service Provider ("TSP") is defined as any person that (i) is not an affiliate of the Covered Entity; (ii) provides services to the Covered Entity; and (iii) maintains, processes, or otherwise is permitted access to Nonpublic Information through its provision of services to the Covered Entity. II. Substantive Requirements A Covered Entity is expected to maintain a written cybersecurity policy or policies and implement a risk-based cybersecurity program. A Covered Entity must also satisfy specific requirements related to (i) risk assessment, (ii) personnel, (iii) application security, (iv) access privileges, (v) Cybersecurity Event notification, (vi) multi-factor authentication, (vii) encryption, (viii) audit trail, (ix) data disposal, (x) TSPs and (xi) reporting to NYDFS. The Final Regulations provide phase-in periods for certain requirements and exemptions for certain Covered Entities. Cybersecurity Policy and Program. A Covered Entity is required to maintain a cybersecurity program that is based on its risk assessment (discussed below) and designed to identify and assess cybersecurity risks; protect information systems and Nonpublic Information; detect, mitigate and recover from Cybersecurity Events; and fulfill applicable regulatory reporting obligations. A Covered Entity is required to implement its cybersecurity program through written policies and procedures that are based on its risk assessment, and such policies and procedures should be approved by a senior officer or the board of directors (or equivalent body). To the extent applicable, such policies and procedures should address: • Information security; • Data governance and classification; • Asset inventory and device management; 3 Mayer Brown | Cybersecurity: NY Adopts Final Regulations for Banks, Insurance Businesses and Other Financial Services Institutions • Access controls and identity management; • Business continuity and disaster recovery planning and resources; • Systems operations and availability concerns; • Systems and network security; • Systems and network monitoring; • Systems and application development and quality assurance; • Physical security and environmental controls; • Customer data privacy; • Vendor and TSP management; • Risk assessment; and • Incident response. Risk Assessment and Testing Requirements. A Covered Entity must conduct a periodic risk assessment of its information systems to inform its cybersecurity program. The risk assessment should reflect changes in controls and technology, as well as evolving threats and cybersecurity risks to the Covered Entity. The risk assessment must be documented and should be conducted in accordance with written policies and procedures and include specifications for how the Covered Entity will accept or mitigate identified risks. To the extent it does not engage in effective continuous monitoring, or use other systems to identify vulnerabilities, a Covered Entity is required to conduct annual risk-based penetration testing and biennial vulnerability assessments to gauge the effectiveness of its cybersecurity program. In the FAQs, the NYDFS clarified that continuous monitoring means that the Covered Entity "has the ability to continuously, on an ongoing basis, detect changes or activities within a Covered Entity's Information Systems that may create or indicate the existence of cybersecurity vulnerabilities or malicious activity." Manual log review and firewall configurations would not qualify under this definition. Chief Information Security Officer and Personnel. A Covered Entity must designate a Chief Information Security Officer ("CISO"), who should be responsible for overseeing and implementing the Covered Entity's cybersecurity program and enforcing its policy. At least annually, the CISO must provide a report to the Covered Entity's board or other governing body on the cybersecurity program and material cybersecurity risks, considering, as applicable, features including material Cybersecurity Events and the overall effectiveness of the program. Certain CISO functions may be outsourced to an affiliate or TSP, but a Covered Entity nevertheless remains responsible for complying with the Final Regulations. A Covered Entity is required to employ cybersecurity personnel sufficient to maintain and execute the Covered Entity's cybersecurity program. The cybersecurity personnel must be subject to ongoing subject-matter training requirements, and all of a Covered Entity's personnel must undergo regular cybersecurity awareness training that is updated to reflect risks identified in its periodic risk assessment (discussed above). The Covered Entity also must implement risk-based controls to monitor the activities of authorized personnel to detect unauthorized access or use of Nonpublic Information. Application Security. A Covered Entity must implement and comply with written procedures and standards for the secure development of inhouse applications and testing of externally developed applications. These written materials must be periodically reviewed, assessed and updated by the CISO or a qualified designee. Access Privileges and Identity Management. Covered Entities are required to periodically review the access privilege of authorized users of its systems, as well as limit access privileges as appropriate, based on their risk assessment. Incident Reporting and Cybersecurity Event Notification. A Covered Entity must 4 Mayer Brown | Cybersecurity: NY Adopts Final Regulations for Banks, Insurance Businesses and Other Financial Services Institutions put in place a written incident response plan designed to enable the entity to promptly respond to and recover from a Cybersecurity Event materially affecting the confidentiality, integrity or availability of its systems. The Final Regulations specifically require an incident response plan to address seven areas: • Internal processes for responding to a Cybersecurity Event; • Goals of the incident response plan; • Clearly defined roles, responsibilities and levels of decision-making authority; • External and internal communications plans and information sharing; • Identification of requirements for the remediation of identified weaknesses; • Documentation and reporting of Cybersecurity Events and related incident response activities; and • Evaluation and revision as necessary of the incident response plan following a Cybersecurity Event. Additionally, Covered Entities are required to notify NYDFS within 72 hours after becoming aware of any Cybersecurity Event with a "reasonable likelihood of materially harming any material part of the normal operation(s) of the Covered Entity" or for which notice must be provided to any government body, selfregulatory agency or other supervisory body. Multi-factor Authentication. The Final Regulations mandate the use of multi-factor authentication methods (e.g., password and token or text messaging code) for individuals accessing the Covered Entity's internal systems from an external network unless the CISO has approved the use of an equivalent or more secure alternative. The Final Regulations also require the use of effective controls, which may include multi-factor or risk-based authentication (requiring additional verification, such as the use of challenge questions, when anomalies or changes in normal use patterns of a user are detected) in other situations, based on the Covered Entity's risk assessment. Data Encryption. Based on its risk assessment, a Covered Entity will need to encrypt Nonpublic Information that it stores or transmits over external networks, though the Final Regulations provide that where encryption is currently infeasible, appropriate alternative compensating controls may be reviewed and approved by the CISO so long as they are rereviewed at least annually. Audit Trail. A Covered Entity must, based on its risk assessment, maintain (i) its systems so that it is able to reconstruct material financial transactions to support normal operations and (ii) audit trails that are designed to detect and respond to Cybersecurity Events that present a material risk to the Covered Entity. These transaction records must be maintained for at least five years, and the audit trail records must be maintained for at least three years. Data Disposal. A Covered Entity must have policies and procedures for the secure disposal of Nonpublic Information that is no longer necessary for its business, except where retention is required by another law or regulation. Third Party Service Providers. The use of TSPs as a potential point of access for unauthorized parties continues to be a particular area of concern for NYDFS and other regulators. The Final Regulations, therefore, overlay on TSPs most of the provisions applicable to Covered Entities by directing Covered Entities to develop written policies and procedures designed to ensure security of systems and data accessible to, or held by, TSPs. Covered Entities are expected to perform a risk assessment on their TSPs and conduct due diligence on, and periodic risk-based assessments of, their TSPs' cybersecurity practices. TSPs would be required to meet minimum cybersecurity standards (defined by the Covered Entities) in order to do business 5 Mayer Brown | Cybersecurity: NY Adopts Final Regulations for Banks, Insurance Businesses and Other Financial Services Institutions with Covered Entities. Additionally, each Covered Entity would be required to establish "preferred provisions" for service contracts with their TSPs addressing (i) the use of access controls and multi-factor authentication, (ii) encryption of Nonpublic Information in transit and at rest, (iii) prompt notification to the Covered Entity of certain Cybersecurity Events and (iv) representations and warranties from the TSPs concerning the policies and procedures that relate to the security of the Covered Entity's systems or Nonpublic Information. Annual Certification. The board of directors (or one or more of the senior officers of the Covered Entity) are required to certify the Covered Entity's compliance with the Final Regulations to NYDFS on an annual basis by February 15 of each year beginning in 2018. To the extent that a Covered Entity identifies areas of needed improvement, the certification must address these areas and the remediation that is underway or planned. All of the materials supporting the certification must be maintained for five years and made available for inspection by NYDFS. Phase-in Period. A Covered Entity must generally comply with the Final Regulations as of August 28, 2017 (180 days after the Effective Date). A Covered Entity, however, is not required to comply with: 1. (i) CISO reporting, (ii) penetration testing, (iii) vulnerability assessment, (iv) risk assessment, (v) multi-factor authentication and (vi) enterprise-wise cybersecurity awareness training until March 1, 2018; 2. (i) audit trail, (ii) application security, (iii) data disposal, (iv) employee monitoring and (v) encryption requirements until September 3, 2018; and 3. The TSP requirements until March 1, 2019. Exemptions. A Covered Entity that, when aggregated with its affiliates, has (i) fewer than ten New York employees, (ii) less than $5 million in New York revenue or (iii) less than $10 million in total assets is required to satisfy only the (1) cybersecurity policy and program, (2) access privileges, (3) risk assessment, (4) TSP, (5) data disposal and (6) NYDFS notice and reporting requirements. Individuals who are associated with a Covered Entity do not need to develop their own cybersecurity program if they are covered by the cybersecurity program of the Covered Entity with which they are associated. A Covered Entity that does not have information systems nor control or use Nonpublic Information is required to satisfy only the (1) risk assessment, (2) TSP, (3) record retention, and (4) NYDFS notice and reporting requirements. A Covered Entity must file a notice with NYDFS by September 27, 2017, to rely on any of the foregoing full or partial exemptions from the Final Regulations.3 Certain specialized insurance institutions (i.e., charitable annuity societies, non-New York risk retention groups, and accredited and certified reinsurers) are exempt from the Final Regulations. III. Takeaways As noted in our September 22, 2016, Legal Update, the Final Regulations will affect financial institutions in a number of industries, including insurance, banking, consumer lending and money transmission. Although the Final Regulations are less prescriptive than the earlier proposals, they still impose significant requirements on Covered Entities and will require particular attention over the next few months to ensure compliance by August 28, 2017. Covered Entities that operate in multiple states or that are part of integrated financial groups should assess their operations to determine which legal entities, systems and TSPs are inscope. In addition, Covered Entities should review their existing policies and procedures to identify and remediate any gaps with the requirements set forth in the Final Regulations. Failure to take these actions may present issues when the NYDFS conducts its next examination 6 Mayer Brown | Cybersecurity: NY Adopts Final Regulations for Banks, Insurance Businesses and Other Financial Services Institutions or the Covered Entity is required to certify its compliance with the Final Regulations in February 2018. For more information about the topics raised in this Legal Update, please contact any of the following lawyers. Rajesh De +1 202 263 3366 [email protected] Jeffrey P. Taft +1 202 263 3293 [email protected] David A. Simon +1 202 263 3388 [email protected] James R. Woods +1 212 506 2390 [email protected] Lawrence R. Hamilton +1 312 701 7055 [email protected] Steven M. Kaplan +1 202 263 3005 [email protected] Thomas J. Delaney +1 202 263 3216 [email protected] Stephen Lilley +1 202 263 3865 [email protected] David L. Beam +1 202 263 3375 [email protected] David A. Tallman +1 713 238 2696 [email protected] Matthew Bisanz +1 202 263 3434 [email protected] Endnotes 1 NYDFS, Press Release (Feb. 16, 2017); Cybersecurity Requirements for Financial Services Companies, XXXIX (No. 9) N.Y. Reg. 3 (Mar. 1, 2017) (codified at N.Y. Comp. Codes R. & Regs. tit. 23, pt. 500). 2 NYDFS, Frequently Asked Questions Regarding 23 NYCRR Part 500 (Mar. 13, 2017). 3 NYDFS, Key Dates under New York's Cybersecurity Regulation (23 NYCRR Part 500) (Mar. 16, 2017). Mayer Brown is a global legal services organization advising clients across the Americas, Asia, Europe and the Middle East. Our presence in the world's leading markets enables us to offer clients access to local market knowledge combined with global reach. We are noted for our commitment to client service and our ability to assist clients with their most complex and demanding legal and business challenges worldwide. We serve many of the world's largest companies, including a significant proportion of the Fortune 100, FTSE 100, CAC 40, DAX, Hang Seng and Nikkei index companies and more than half of the world's largest banks. We provide legal services in areas such as banking and finance; corporate and securities; litigation and dispute resolution; antitrust and competition; US Supreme Court and appellate matters; employment and benefits; environmental; financial services regulatory and enforcement; government and global trade; intellectual property; real estate; tax; restructuring, bankruptcy and insolvency; and wealth management. Please visit www.mayerbrown.com for comprehensive contact information for all Mayer Brown offices. Any tax advice expressed above by Mayer Brown LLP was not intended or written to be used, and cannot be used, by any taxpayer to avoid U.S. federal tax penalties. If such advice was written or used to support the promotion or marketing of the matter addressed above, then each offeree should seek advice from an independent tax advisor. Mayer Brown comprises legal practices that are separate entities (the "Mayer Brown Practices"). The Mayer Brown Practices are: Mayer Brown LLP and Mayer Brown Europe-Brussels LLP, both limited liability partnerships established in Illinois USA; Mayer Brown International LLP, a limited liability partnership incorporated in England and Wales (authorized and regulated by the Solicitors Regulation Authority and registered in England and Wales number OC 303359); Mayer Brown, a SELAS established in France; Mayer Brown Mexico, S.C., a sociedad civil formed under the laws of the State of Durango, Mexico; Mayer Brown JSM, a Hong Kong partnership and its associated legal practices in Asia; and Tauil & Chequer Advogados, a Brazilian law partnership with which Mayer Brown is associated. Mayer Brown Consulting (Singapore) Pte. Ltd and its subsidiary, which are affiliated with Mayer Brown, provide customs and trade advisory and consultancy services, not legal services. "Mayer Brown" and the Mayer Brown logo are the trademarks of the Mayer Brown Practices in their respective jurisdictions. This publication provides information and comments on legal issues and developments of interest to our clients and friends. The foregoing is not a comprehensive treatment of the subject matter covered and is not intended to provide legal advice. Readers should seek legal advice before taking any action with respect to the matters discussed herein. © 2017 The Mayer Brown Practices. All rights reserved.
Mayer Brown - Rajesh De, Jeffrey P. Taft, David A. Simon, James R. Woods, Lawrence R. Hamilton, Steven M. Kaplan, Thomas J. Delaney, Stephen Lilley, David L. Beam, David A. Tallman and Matthew Bisanz
IT & Data Protection
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Q: Redirecting a page after a PDF download I have an aspx (say 1.aspx) page from where first I am downloading a pdf file and then I want to redirect to some Thanks.aspx page. The code is this:
protected void btnSubmit_Click(object sender, EventArgs e)
{
    string pathId = string.Empty;
    if (Page.IsValid)
    {
        try
        {
            pathId = hidId.Value;
            DownloadPDF(pathId);

            Response.Redirect("Thanks.aspx");
        }
        catch (Exception ex)
        {
            throw ex;
        }
    }
}

protected void DownloadPDF(string pathId)
{
    if (!(string.IsNullOrEmpty(pathId)))
    {
         try
        {
            Response.ContentType = "application/pdf";
            Response.AppendHeader("Content-Disposition", "attachment; filename=" + pathId + ".pdf");
            string path = ConfigurationManager.AppSettings["Pdf_Path"].ToString() + "\\" + pathId.Trim() + ".pdf";
            Response.TransmitFile(path);
        }
        catch (Exception ex)
        {
            throw ex;
        }
        finally
        {
            HttpContext.Current.ApplicationInstance.CompleteRequest();
        }
    }
}

The problem is that, the file save dialog is coming properly and I am able to download the file also, but it is not getting redirected to the Thanks.aspx page.
How to resolve this?

A: If the file is just downloaded, no preprocessing is done, you could try the following:
Response.AddHeader("Refresh", "12;URL=nextpage.aspx");

Where the number is the seconds before refresh is done :)

A: I've found it easier to put the PDF download page in an iframe. That way you can activate the PDF download on the client side by just pointing the iframe source to the PDF download page. After that you can either move to a new page, or just show the thank you text right that on the page that has the iframe in it.

A: In HTTP, a request can only have a single response. Since the first response is the PDF file, the seconds response (i.e. the redirect) cannot be implemented.
You can try to redesign the two pages by redirecting to thanks.aspx and have thanks.aspx start the download automatically.

A: A Response.Redirect actually sends a response to the browser that basically says this resource has moved to some other URL. However, you're trying to send a file down in a response too, so those two things are probably clashing with each other. Try sending back a little JavaScript that sends them to the page you want to send them too instead of using a Response.Redirect.
ScriptManager.RegisterStartupScript(Me, Me.GetType(), "redirectScript", "window.location.href='whateverurlhere.aspx';", True)

A: See the article mentioned in this accepted answer: https://stackoverflow.com/a/11018277/1037864
(direct link: http://gruffcode.com/2010/10/28/detecting-the-file-download-dialog-in-the-browser/)
The idea is to set a cookie and send it together with the file. Meanwhile you let the waiting page block the UI while it is waiting for the cookie to arrive.

A: I tried many things (like the ideas here) but nothing worked for my particular situation. In the end for me I used an approach where my C# sets a cookie that the JavaScript looks for and the form buttons/etc are disabled accordingly until the cookie is detected.
My code is here in case anyone thinks this solution might work for you:
https://gist.github.com/cemerson/9811a384d7f41bc683b2bd9ed4bf5b17

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Board index Serious Stuff News, Current Events & Politics
How idiotic is a country that shuts itself down
Re: How idiotic is a country that shuts itself down
Post by JimC » Thu Jan 10, 2019 7:59 pm
Cunt wrote: ↑
How often do they do this? I know both sides do it, and the claims are that the Dems tend to do it more, but if it is a tactic abused by both sides, it kind of needs pointing out at times like this.
Wasn't the last hissyfit shutdown the one where they made everyone take Obamacare?
If you read the first post in the thread, you would know that I was castigating the idiocy of a political system that permits this to happen, rather than any particular player.
Post by laklak » Thu Jan 10, 2019 8:29 pm
Just shows how dire the average American's financial situation is, they've missed (I think) one paycheck since the shutdown and they're skint. I read that something like 75% of Americans can't cover an unexpected $1000 expense. But everybody has an unlimited cell plan and a new iPhone or S9, and 100M internet, and cable TV, and a new car, and .....
But i'm an old dinosaur who doesn't understand that all those things are necessities.
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Post by Cunt » Thu Jan 10, 2019 8:41 pm
JimC wrote: ↑
If you limited their available tools to a lectern, they would find a way to use THAT to push their agendas, and get in the way.
I don't know why it is such a big deal to the Dems, that they will shut the government over it, but it's hilarious how well it plays into Trumps hands. They really are losing the publicity battle, and he isn't even playing that hard.
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Post by Sean Hayden » Thu Jan 10, 2019 8:59 pm
laklak wrote: ↑
There's something to that. But honestly, you ain't sitting pretty with a boat and house because you ate mac'n cheese 7 days a week. At some point in your life your income jumped up.
For many Americans that hasn't happened and it doesn't look like it's ever going to happen. I knew guys in retail who had worked for 15+ years at the same company and were making less than 15 bucks an hour! Worse, these companies love to get rid of full-time employees and that means getting rid of people who've put in the most time with the company.
While my first tech job started at 30 a year and was at 45 within 3 years. That's not a lot of money, but I hardly worked too, and it sure beat working my ass off for nothing.
Cunt wrote:
...I don't know why it is such a big deal to the Dems, that they will shut the government over it...
What a ridiculous statement. Trump made the decision to shut down the government, a petulant action by a spoiled brat. No doubt, in the past, democrats have also made stupid decisions to shut down government, but this time, it's Trump - he owns the shut down, his own words...
He did. I like blaming the Dems (it really is both their faults...) because it triggers lefties.
The 'Orange-Man-Bad' group is hilarious.
Post by laklak » Thu Jan 10, 2019 10:30 pm
Sean Hayden wrote: ↑
Yeah that's true, it was basically the work in the mideast that did it. What I did do was refuse to live on credit. Paid off my student loans as fast as I could and never bought anything on time except the first house and one car, got my first cell phone (other than a work phone they paid for) in 2006.
Though I could actually eat mac and cheese 7 days a week, 'cuz I make one motherfucker of a mac-n-cheese. With bacon.
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Post by pErvinalia » Thu Jan 10, 2019 10:39 pm
Wasn't it you telling us that you can't label groups unless the people in it self-identify? You've basically become what you used to rail against (people labelling others as alt-right).
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Post by Cunt » Thu Jan 10, 2019 10:49 pm
Identity politics IS a pretty stupid game, but how else to classify us lefties, aside from lumping them together by voting habits?
I'm talking about the NPC thing, dolt.
If it looks like an NPC, and quacks like an NPC...
Tell me, what is the nicest thing you have found about Trump?
If it looks like an NPCalt-right, and quacks like an NPCalt-right...
pErvinalia wrote: ↑
Yeah, except that I have not ever voted 'right'...
I was talking about people who vote left (including myself) not about people who have ideas I disagree with.
If someone has different ideas than you, you have a hard time seeing their humanity. Why not try to find someone who disagrees with you on something important, AND try to see them as a loving, respectful human being?
It's been a good education for me.
What in the fuck are you on about? You said we can't label people as alt-right unless they self identify. You then label people as NPCs, despite them not self identifying.
The NPC label is easily dissipated...by saying something one of those 'NPC's' couldn't say.
In this context, it's saying something positive about Trump's changes.
Go ahead. Give it a try. Tell us about the thing you do respect about his actions since becoming president.
Or keep sounding like an echo of CNN. Whatever feels right to you.
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Reports: Urinary Tract Infection Therapeutics Market Regional Analysis Size, Suppliers to 2031
Home > Healthcare IT > Urinary Tract Infection Therapeutics Market Regional Analysis Size, Suppliers to 2031
Urinary Tract Infection Therapeutics Market
Urinary Tract Infection Therapeutics Market: Information by Drug (Penicillin and Combinations, Quinolones, Cephalosporin), Indication (Complicated UTI), and Region – Forecast till 2031
The Total Addressable Market (TAM) for Urinary Tract Infections Therapeutics Market size was valued at USD 8.92 billion in 2022. It is estimated to reach an expected value of USD 11.85 billion by 2031, registering a CAGR of 3.2% during the forecast period (2023-2031). Patients with crucial issues and diabetes are vulnerable to various infectious diseases. The patient is vulnerable to urinary tract infections. Some of the symptoms in these patients include urination, pain, and irritation. UTI is a disease that affects over 15% of the population. This infection can affect people of all ages. The rising Prevalence of Diabetes and kidney stones raises the number of urinary tract infection (UTI) cases, which raises drug demand, driving the global urinary tract infection market for therapeutics. The combination drugs are effective against these infections. The availability of such a diverse range of therapeutics is expected to drive demand for UTI treatment in the market. The growing geriatric population creates a high demand for the market. The elderly are particularly vulnerable to such infections. UTI is a common problem among older women over the age of 65. The aging population will have a positive impact on the UTI treatment market. All these UTI treatment market drivers will contribute to the treatment market's exceptional growth rate.
Global Urinary Tract Infection Therapeutics Market Drivers
Increasing Prevalence of Diabetes and Kidney Stones
With the rising Prevalence of Diabetes and kidney stones, the number of urinary tract infection (UTI) cases rises, driving the global urinary tract infection therapeutics market. According to the International Federation of Diabetics 2021, in 2020, Diabetes affected approximately 463 million adults aged 20 to 79 years; by 2030, which is expected to rise to 643 million, and by 2045, it is expected to reach 700 million. In several countries, the proportion of people with type 2 diabetes is increasing. Diabetes affects 79% of adults in low- and middle-income countries. Because the sugar in the urine serves as a breeding ground for bacteria, urinary tract infections can be particularly problematic for people with diabetes. As a result, the demand for UTI therapy treatment in such cases has increased. As a result, it is expected to boost the market under consideration.
According to the American Academy of Family Physicians (AAFP), kidney stones are a prevalent illness, with an annual incidence of eight cases per 1,000 adults. In addition, approximately 13% of men and 7% of women may get kidney stones at some point in their lives, and in the US, the incidence of urinary retention ranges from 4.5 to 6.8 per 1,000 males per year. According to the study titled "Prevalence and Associated Factors of Urinary Tract Infections among Diabetic Patients," published in Health Science Journal 2019, UTI was found to be 38 % more common in diabetic patients. UTI was found to be more common in females, accounting for 63.16 % of all cases, while males contributed 36.84 % of all cases among the subjects studied. The leading cause of UTI in diabetic patients is high blood sugar levels. Thus, owing to the abovementioned factors, the studied market is expected to grow significantly over the forecast period.
Launch of Combination Drugs
The combination drugs prove efficient for these infections. The availability of this wide range of therapeutics is expected to boost the UTI treatment market demand. In July 2019, the FDA will continue to encourage the development of new, secure antibacterial medications to give patients more options for treating severe infections, for example. Adults with complicated urinary tract infections (cUTI) and intra-abdominal infections may use Recarbrio (imipenem, cilastatin, and relebactam), an antibacterial medication, according to the United States Food and Drug Administration. Merck & Co. Inc. received FDA approval for Recarbrio as a treatment. So, it is anticipated that introducing the chaos combination drug will propel the market during the forecast period.
Lefamulin, a pleuromutilin antibiotic that inhibits the large subunit of bacterial ribosomes, was also approved for medical use in the United States in August 2019 and the European Union in July 2020. A novel combination antibiotic for treating patients with specific confirmed or suspected Gram-negative bacterial infections requiring hospitalization, Zavicefta, was similarly announced by Pfizer Inc. in July 2018 that it is now available in the UK and Germany. Pfizer similarly launched Zavicefta in additional international markets at the end of 2018. The creation of Zavicefta was prompted by the requirement for new antibiotics for difficult-to-treat Gram-negative bacteria, many of which have become increasingly resistant to the antibiotics currently available. Furthermore, in February 2020, a French pharmaceutical company announced Exblifep, a combination of enmetazobactam, a novel extended-spectrum beta-lactamase inhibitor, and cefepime, a fourth-generation cephalosporin that met primary endpoints in a clinical trial for complicated UTIs.
Global Urinary Tract Infection Therapeutics Market Restraint
Adverse Effects Associated with the Use of Medication
Every medication or medical procedure has some side effects. The common side effects of Urinary tract infection therapeutics are nausea and vomiting, dry mouth, and soreness. Throat, hoarseness, chills, shivering, confusion, fuzzy thinking, etc. However, according to the Center for Education & Research on Therapeutics, over 2 million adverse drug reactions (ADRs) cases are reported annually, leading to approximately 100,000 deaths. According to the FDA, it is estimated that, in the United States, over 350,000 ADRs occur in nursing homes each year. With an increase in the number of cases of ADRs being reported globally, there is an awareness among the population about the adoption of drugs, which is acting as a major restraint for the urinary tract infection therapeutics market. Side effects can include rash, dizziness, nausea, diarrhea, and yeast infections. More severe side effects can include antibiotic-resistant infections side effects associated with standard UTI therapies like fluoroquinolones, such as variations in blood sugar levels and central nervous system problems such as anxiety, seizures, and insomnia may impede urinary tract infection treatment market expansion to some extent during the forecast timeframe.
Global Urinary Tract Infection Therapeutics Market Opportunities
Research and Development in UTI treatment
Research and Development in UTI treatment are expected to provide lucrative growth opportunities for global urinary tract infection treatment market participants. For example, Lupin received approval from the US Food and Drug Administration (FDA) in July 2018 for generic Nitrofurantoin capsules. Alvogen Malta Operations Ltd sells a generic version of Macrodantin. It treats urinary tract infections caused by Staphylococcus aureus, enterococci, and other bacteria.
In addition, Spero Therapeutics, Inc. announced in May 2020 that patient enrollment in its Phase 3 clinical trial of tebipenem HBr to treat complicated urinary tract infection (UTI) and acute pyelonephritis, ADAPT-PO, had been completed (AP). The US FDA approved the Recarbrio drug in July 2019 to treat cUTI and complicated intra-abdominal infections in adults. Achaogen, Inc. received US FDA approval for ZEMDRI to treat cUTIs in adults in June 2018. Furthermore, in July 2019, Healthy.io, a developer of smartphone camera-based solutions, announced an agreement with Walgreens Boots Alliance, Inc. to place Healthy.io's Dip UTI test kits in Boots pharmacies across the globe. Thus, over the forecast period, there is a massive opportunity in the market, and it is expected to launch many therapeutic drugs over the studied period.
The global urinary tract infections therapeutics market is segmented by drug, indication, and region.
By drug, the global urinary tract infections therapeutics market is bifurcated into penicillin and combinations, cephalosporin, azoles and amphotericin B, quinolones, nitrofurans, and other drugs. The quinolones drugs segment dominated the market and is expected to grow at a CAGR of 3% during the forecast period. Quinolone antibiotics are bactericidal antibiotics that destroy bacteria directly. They impede the action of bacterial type II topoisomerases, DNA gyrase, and topoisomerase IV, turning them into hazardous enzymes that cause irreversible double-stranded breaks in the chromosome. A study titled 'Levofloxacin Versus Ciprofloxacin in the Treatment of Urinary Tract Infections: Evidence-Based Analysis' in 2021 reported that UTIs (urinary tract infections) are one of the most prevalent bacterial infections, both in the community and in hospitals. Fluoroquinolones, such as levofloxacin and ciprofloxacin, are commonly used to treat urinary tract infections, and this drives the market. Furthermore, a study titled 'Fluoroquinolone use for uncomplicated urinary tract infections in women: a retrospective cohort study in 2019 reported that Fluoroquinolones had been linked to better clinical outcomes in women with uncomplicated urinary tract infections, and this condition will improve the usage of quinolones by the patients and thus drives the market. Hence, owing to the above conditions, the quinolones segment of the urinary tract infection therapeutics market is expected to grow over the forecast period.
By indication, the global urinary tract infections therapeutics market is segmented into complicated UTI, uncomplicated UTI, and other indications. The complicated UTI segment dominated the market and is expected to grow at a CAGR of 3.5% during the forecast period. Infections that occur despite the presence of anatomical preventive measures (complex UTI in males) Infections that arise from anatomical anomalies, such as obstructions, hydronephrosis, renal tract calculi, or colovesical fistula. A study titled 'Complicated Urinary Tract Infections in 2021 reported that Complicated urinary tract infections have a higher likelihood of treatment failure, necessitating longer antibiotic courses and, in some cases, further testing, and this condition depicts that complicated urinary tract infections lead to more prolonged usage of antibiotics, and this drives the urinary tract infection therapeutics market. In addition to the above, several key players submitted applications to the United States Food and Drug Administration Tebipenem HBr for the treatment of Complicated Urinary Tract Infections, including Pyelonephritis, has been submitted to the United States Food and Drug Administration by Spero Therapeutics, and this drives the market. Furthermore, Cefiderocol has been approved by the Food and Drug Administration for treating complex urinary tract infections (cUTIs) caused by gram-negative bacteria, including kidney infections, in patients with limited or no other treatment options, and this drives the market. Hence, the ongoing research studies, recent product developments, and launches are expected to boost the complicated UTI segment of the urinary tract infection therapeutics market due to the above conditions.
By region, the global urinary tract infections therapeutics market is segmented into North America, Europe, Asia Pacific, South America, and MEA.
North America dominated the market and is estimated to grow at a CAGR of 3.3% over the forecast period. Due to better healthcare infrastructure, effective government policies, a sizable base of multinational corporations, and a high level of public awareness regarding diagnostic testing and medical devices, the United States holds one of the most significant shares in the market under study. According to the American Academy of Family Physicians (AAFP), kidney stones are a prevalent illness, with an annual incidence of eight cases per 1,000 adults. FIn addition, approximately 13% of men and 7% of women may get kidney stones at some point in their lives, and in the US, the incidence of urinary retention ranges from 4.5 to 6.8 per 1,000 males per year. Moreover, there have recently been several Food and Drug Administration treatment approvals for UTIs. For instance, Recarbrio (imipenem, cilastatin, and relebactam) was licensed by the United States Food and Drug Administration to treat individuals with complex urinary tract infections (UTI) and complicated intra-abdominal infections (cIAI) in 2019. Therefore, owing to the above factors, the rise in urinary tract infection cases, kidney stones, and other associated diseases with urinary tract infections in the United States is expected to witness growth over the forecast period.
Europe is the second largest region. It is estimated to reach an expected value of USD 3188 million by 2031, registering a CAGR of 3.4%. Germany's urinary tract infection therapeutics market is expected to grow significantly during the forecast period because of the increasing Prevalence of urinary tract infections and kidney stones, the rising geriatric population, and increasing government initiatives. According to the article published by WA Manaco in springer journal 2021, Urinary tract infections (UTIs) are a frequent cause for patient in Germany who visits family medicine, with a prevalence ranging between 1.7 and 3.1%. Thus, increasing Prevalence in the country is expected to boost the market. The European government provides specific guidelines to prevent drug resistance. For instance, in a study published in BMJ open journal in 2021, titled "REDuction of Antibiotic Resistance (REDARES) in urinary tract infections using treatments according to national clinical guidelines," through the study searcher identified therapeutic regime that can help in the reduction of antibiotics resistance. Thus, such a therapeutic regime minimized the resistance and increased the demand for antibiotics to treat UTI infection. It is expected to boost the market over the forecast period.
Asia Pacific is the third largest region. China is among the fastest-growing regions in the pharmaceuticals domain. The primary reason for the market's growth is China's rapidly aging population, which indicates that the country is expected to experience an explosion of chronic conditions and infectious diseases, which require drugs as a part of treatment which is expected to drive the urinary tract infection therapeutics market. For instance, in a study titled 'Prevalence, incidence, and risk factors of urinary tract infection among immobile inpatients in China: a prospective, multicenter study in 2020, immobile inpatients have a high risk of urinary tract infection (UTI). A urinary tract infection (UTI) was found in 393 of the 23,985 immobile individuals. In hospitalized immobile patients, the frequency and incidence of UTIs were 1.64 % (393/23 985) and 0.69 per 1000 patient days, respectively. The catheter-associated UTI infection rate was 2.25 per 1000 urine catheter days. This drives the urinary tract infection therapeutics market, increasing the demand for therapeutics to treat urinary tract infections (UTIs).
Major companies in the global urinary tract infections therapeutics market are AstraZeneca, Bayer AG, Cipla Inc., GlaxoSmithKline PLC, Shionogi & Co. Ltd, Novartis AG, and Pfizer.
November 2022 - The top three ranking of AstraZeneca in the 2022 Access to Medicine Index (AMI) is a result of the company's pioneering efforts to improve international health systems and broaden patients' access to adequate, affordable treatments.
November 2022 - Enhertu (trastuzumab deruxtecan), a product co-developed by AstraZeneca and Daiichi Sankyo, has been recommended for approval in the European Union (EU) as monotherapy to treat adult patients with advanced HER2-positive gastric or gastroesophageal junction (GEJ) adenocarcinoma who have previously received a trastuzumab-based regimen.
Global Urinary Tract Infection Therapeutics Market: Segmentation
By Drug
Penicillin and Combinations
Azoles and Amphotericin B
Nitrofurans
By Indication
Complicated UTI
Other Indications


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