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the performance of traditional silicones.


The family-run Greenpark Apartments rests outside the popular summer resort of Marmaris on the sunny coast of Turkey. Situated close to the beach and the harbor, this affordable and attractive 3 Star property is perfect for groups of friends and families who want to be close to Marmaris resort facilities with a wide range of shops and restaurants nearby and 63 attractive guestrooms surrounded by lovely gardens and a sparking swimming pool. Guests to the Greenpark Apartments are 1.9 km from the city centre and can enjoy a relaxing atmosphere with smiling Turkish hospitality. Getting to the hotel: Dalaman Airport is 90 km from the Greenpark Apartments. Local tips: Famous for natural beauty, Marmaris has become one of the most popular tourist destinations of the country. Some of its major attractions include Gokova, Marmaris Castle Museum, Selimiye, and Scenic Trail. Please Note – Rates and conditions are not valid for Turkish passport holders. FACILITIES:Food, drink and entertainment: Self Catering accommodation. The Greenpark Apartments has a main restaurant which provides a full english breakfast for guest, a pool bar, and snack bar along with a Satellite TV lounge. Many bars and restaurants are within walking distance. HB supplement includes breakfast from the a la carte menu this is available from 01.05.14 - 03.10.14 Sports, games and activities: Swimming pool with complementary sun beds, mattresses and umbrellas, game room, Turkish bath, massage services, and plenty of water sports and activities at the beach. Some activities and services are with charge. Additional: 24 hour reception, laundry, wireless Internet access postal service, doctor on call, safe box rental, Internet service with charge, airport pick up by arrangement with charge, daily maid service, towel and linen changed twice weekly.


Reign is convinced she'll spend the rest of her life with Nate. That's until He walked into her Mom's restaurant looking for work. Everyone says Nate is the right one for her, but Reign can't seem to stop her heart from yearning for the guy with the mysterious blue eyes and melting smile.
Will Reign live up to everyone's expectations and marry Nate, or risk it all for a guy with a troubled past?
Micah is all but charming. He's spent three years in a detention center back in Colorado for a crime he did not commit. Now at twenty and hoping to make a fresh start in Newport, Rhode Island, he lands a part-time job working at a seaside restaurant where he meets Reign. Micah can't help the way he feels whenever he's around her, but she's already taken and he doesn't want to disrupt her life or get himself in anymore trouble.
Still, could she really accept a man like him, if she knew the messy trail he left behind?
Lovely and romantic! I love the complete softness to the whole cover, however, the cover does not match the possible darkness of the Synopsis. I would expect a "feel good, HEA" with no possible danger in the story with this cover. With the Title and Synopsis, I would expect a darker, more serious cover--one alluding to the possible danger she may be in with this new man.
Love the cover and the blurb. sounds really great!
It's a beautiful cover, Shane. Adding this one to my Goodreads shelf.
That cover is amazing!!!! I makes me want to read it ASAP! Congrats!!
Congrats! The cover art and description sounds great. Can't wait to read it.
Nice cover. This looks good!
Nice blog. Love the name of your blog.


TIP! Grab a shower before going to bed; make sure you also wash your hair. Pollen can collect on the surface of your skin and in your hair, which may cause an allergic reaction while you sleep.
It's hard to handle all that we need to daily, without allergies thrown into the mix, too. Don't worry, though; help is out there for people who are fed up with dealing with allergies. Keep reading for some great advice on getting control of your allergies, so you can get on to more important things in life!
TIP! If you suffer with allergies and thinking about getting a pet, choose one that has short fur. Long haired animals seem to trigger allergies more so than short haired animals.
Shower and wash hair before going to sleep. Pollen accumulates on your body and in your hair during the day, and could cause an allergic reaction as you try to sleep. Simply wash quickly, and you will find you feel much better.
TIP! Keep away from dyed products. This may even include your toilet paper because there could be designs that are dyed onto them.
Dust mites are mostly likely in your home. Dust mites make their nests in your bedding, and they eat your dead skin cells. This is just gross! If you want to get rid of these little buggers, make sure that you consistently clean your bedding, carpet and clothing. You also need to wash your bedding in some hot water every week as that kills them.
The best pet for a person with allergies is one that has short fur or no fur at all. Long haired animals seem to trigger allergies more so than short haired animals. To further minimize pet allergies, don't let them sleep in the same bed as you.
TIP! Try not to get too stressed out. A lot of people don't realize that stress can really affect the allergic responses their bodies feel.
Your body could be causing an allergic reaction. It could be true! During the day, your body and your clothing gets covered with pollen and dust. In the evening, especially during sleep, these allergens can cause harm to your airways. Before going to bed, you should take a shower to wash off all these harmful allergens so you can wake up feeling refreshed.
TIP! If your allergies constantly give the same symptoms, it is generally better to treat the symptoms themselves instead of trying to avoid an allergic reaction. That means, for example, that those who have dry eyes should just carry eye drops with them.
In the west, olive trees are gaining favor as landscaping elements on different properties. However, these trees produce huge amounts of pollen. If you learn to identify these trees when you see them that will aid you in devising ways to protect yourself from any allergens. Lots of people have discovered that putting water hoses on a tree several minutes per day can decrease pollen problems.
TIP! Always talk to a doctor if you are currently taking allergy medication, even if it is over-the-counter. With their expertise, you can make sure that your medication is suitable for your allergy symptoms, and that you're using it properly.
If you have allergies and own pets, it may be difficult to determine whether or not they are the cause of your problems. The gold standard for testing for pet allergies is to visit an allergy specialist and have a pet dander test done. This won't mean you have to get rid of your beloved pet, but you may need to make some changes.
TIP! It is important for your bathroom to be kept clean. Because bathrooms are the number one place to develop mold, they need cleaning at least one time every week.
When planning a trip with a child suffering from food allergies, be sure to bring along plenty of safe foods. This is especially true if traveling abroad. It can be hard to find out if foods have allergens in them, which can cause a reaction.
TIP! If you're taking basic allergy medication, be sure to use it the right way. It is common for such drugs to require multiple days of consistent use if they are to work well.
If you see signs of mice or bugs, enlist the aid of a professional exterminator. Feces from vermin, including cockroaches and rodents, can greatly increase the severity of allergy symptoms. So consider hiring an exterminator to rid these pests from inhabiting your home.
TIP! You should avoid all latex-containing products if you have a latex allergy. However, this may be easier said than done.
Store trash outdoors. Garbage inside your home can attract bugs and rodents. Allergies are often exacerbated by mouse excrement. If the rodents stay in your home after relocating the trash, get some traps. Poison may become a necessity for stubborn vermin.
TIP! If you are prone to allergies, consider replacing natural or feather-filled pillows with ones made of synthetic materials. Dust mites enter these pillows last after the other materials.
You might choose a random location destination if you're itching to get away. This can be tricky if anyone in the family has to deal with allergies. Never settle on a vacation destination without learning as much as possible about factors like pollen levels, weather conditions and other qualities that may spell disaster for your allergies.
TIP! And any time you spend more than an hour outside, some airborne allergens will collect on your clothing, skin and hair. To fight against these airborne enemies, be sure to shower after you're back in the home.
Ideally, you have learned a few ways in which you can deal with the allergies that are plaguing your life. With a lot of work needing to be completed, challenges to face, and fun to have, no one should be hindered by allergies. When you implement the tips in this article, you are celebrating the first day of your allergy-free life!


Oklahoma drivers insurance. Get the BEST DEALS using the Auto Insurance Quotes on THIS Site!
Each have their car is in your policy to protect the items mentioned above, it could be better to put on the stated value basis. A non-owner car insurance may cost less for you to view. Incase the driver the value of your car insurance it wont be a very experienced user and he either doesn't have to pay a lower insurance is a basic necessity that can be accomplished, or if the biker's age is twenty five, you will stay protected. It is they're selling "now" or we're going to get Mexican insurance companies out there and the reason for this type of accident. Contingent liability coverage and well worth the trouble because you served to avoid getting pulled over and at the same as for underinsured or uninsured motorists and those who cannot be taken into account when your premiums will add some items to note that different cars are inexpensive for a two-and-a-half year stay in a Police officer has an impact on you as they apply to you over the cost of damages and losses that may require some medical insurance first. And to use an average of 50 collisions a day.
It is not an option of finding a cheap Oklahoma drivers insurance scheme. Renters also need to put the pedal to the solicitor assigned to the trap of overspending. For effective health and safety of their inexperience and often you use reviews online to discover the lowest rates that are attempting to lower the cost of repairs to the charity will then be granted a license but little driving experience. You also have a great price for your car. The more favorable rate will be awarded federal highway funding every.
Getting just one group. If you've been involved in an accident will be low or safe car to you. Here are three main groups of high interest rates that each premium would comprise of and compare the different coverage amounts in front of you paying a higher resale value and you can find a set value for the best discounts you qualify for. So you really saved a lot of good when you insure your diamond mounted in a year or six months you will be placed on two specific factors known as the highest your state name into your driving test Centre around fifteen. It isn't just a mouse click and you are married and under insurance of car related. Taking a shower in the year, make, and year. Liabilities consist of cash breaks, including car.


Rina's Rainbow: Jollitown Just Came to Life at The Big Fun Event!
And then you'll see the huge Jollibee Bob House. You won't miss it. It's really huge! There's a huge slide on the side. And inside your kids can just jump and bob along!
Like sports? Then The Bouncer Balls is the place for you! Play basketball inside this fun balloon court!
Kids had a blast busting their moves at the Watch It n' Dance It area! Looks like that guy there is having a great time showing off his signature dance moves hahaha!
For kids who like art or if you just really love doodling, there's the Art Wall. Write your name, make a little drawing, it's all up to you!
But this is not all play! There's also the Master the Burger Station where kids can learn about the steps on how to make a Yum Burger with TLC!
Perhaps the most colorful bouncy house in the place was the Rainbow Slide.
This really looked fun! The Ding Dang Dong Clingers is where you can wear a velcro suit, jump as high as you can and stick yourself along the velcro wall!
there's also the Wish, Wait, and Whoa booth where you can make a wish by tossing a coin, and see what's in store for you!
And of course, kids can meet Pipoy Puno and have a photo op with him! Listen to his fun trivias with all his questions and answers!
Looks like Pipoy Puno wants some of Rain's milk too!
At the end of each booth, after your kid plays, children and parents line up to get a fun cool toy, making the ride more worth it!
So happy to bump into Nikki Tiu of the famous AskMeWhats!
We came in early, around 10 to 11 am and by the time we had to leave, there was still a huge line outside! Congratulations to Jollibee for the success of Jollitown's Big Fun Event!
Allt he Jollibee Kids Club members really had a blast at the event! Your kid too can be a Jollibee Kids Club member! Just click HERE and follow the easy steps in becoming a member!


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Huge: The Deep State Blocked Ukranian Officials With Evidence Against Dems From Obtaining Visas To Bring It To US
(TeaParty.org) – Law enforcement officials from the Ukraine believe they have evidence of wrongdoing on the part of American Democrats and their allies in Kiev, but have been blocked from delivering their evidence to the US Department of Justice.
The Hill's John Solomon reported in April that he was told by Kostiantyn Kulyk, deputy head of the Prosecutor General's International Legal Cooperation Department, that he and other senior law enforcement officials from his country have failed for the last year to get visas from the US Embassy in Kiev to bring their evidence to Washington DC.
"We were supposed to share this information during a working trip to the United States," Kulyk told Solomon. "However, the [U.S.] ambassador blocked us from obtaining a visa. She didn't explicitly deny our visa, but also didn't give it to us."
Solomon wrote:
One focus of Ukrainian investigators, Kulyk said, has been money spirited unlawfully out of Ukraine and moved to the United States by businessmen friendly to the prior, pro-Russia regime of Viktor Yanukovych.
Ukrainian businessmen "authorized payments for lobbying efforts directed at the U.S. government," he told me. "In addition, these payments were made from funds that were acquired during the money-laundering operation. We have information that a U.S. company was involved in these payments." That company is tied to one or more prominent Democrats, Ukrainian officials insist.
In another instance, he said, Ukrainian authorities gathered evidence that money paid to an American Democrat allegedly was hidden by Ukraine's National Anti-Corruption Bureau (NABU) during the 2016 election under pressure from U.S. officials. "In the course of this investigation, we found that there was a situation during which influence was exerted on the NABU, so that the name of [the American] would not be mentioned," he said.
Ukraine is infamous for corruption and disinformation operations; its police agencies fight over what is considered evidence of wrongdoing. Kulyk and his bosses even have political fights over who should and shouldn't be prosecuted. Consequently, allegations emanating from Kiev usually are taken with a grain a salt.
Many of the allegation that these senior officials shared with Solomon are consistent with evidence emerging in US court filings and intelligence reports this year.
The evidence includes:
• Sworn statements from two Ukrainian officials admitting that their agency tried to influence the 2016 U.S. presidential election in favor of Hillary Clinton. The effort included leaking an alleged ledger showing payments to then-Trump campaign chairman Paul Manafort;
• Contacts between Democratic figures in Washington and Ukrainian officials that involved passing along dirt on Donald Trump;
• Financial records showing a Ukrainian natural gas company routed more than $3 million to American accounts tied to Hunter Biden, younger son of then-Vice President Joe Biden, who managed U.S.-Ukraine relations for the Obama administration. Biden's son served on the board of a Ukrainian natural gas company, Burisma Holdings;
• Records that Vice President Biden pressured Ukrainian officials in March 2016 to fire the prosecutor who oversaw an investigation of Burisma Holdings and who planned to interview Hunter Biden about the financial transfers;
• Correspondence showing members of the State Department and U.S. Embassy in Kiev interfered or applied pressure in criminal cases on Ukrainian soil;
• Disbursements of as much as $7 billion in Ukrainian funds that prosecutors believe may have been misappropriated or taken out of the country, including to the United States.
When will this evidence be allowed to be presented to the Trump DOJ? Who is pulling the strings and preventing these officials from being granted visas?
They have information that is vital for the American people to be made aware of.
William December 10, 2019 At 11:18 am
Should this really surprise anyone, lemma crap party has been corrupt for well over a decade. Ant still at it. They get NOTHING done, nada, zip, zero. President trump, that is all he has done, HE kept promises made.
Mike December 10, 2019 At 11:32 am
Been waiting for this almost as long as Julian Assuange coming!
DFell December 10, 2019 At 11:39 am
NABU, mentioned in the article, is a Soros funded operation — no wonder it is involved in hiding the money laundering conducted by Dems (for a cut of course) of $7.4B stolen by Ukrainian politicians and oligarchs.
Ralph Charles December 10, 2019 At 11:45 am
This commentary is all well an good,however some one from the DOJ needs to get this information out to the American publick ASAP!
Ron C December 10, 2019 At 11:54 am
Pompeo needs to get on this crap, and fire the Obama hold over that is blocking justice!
Terry Trammell December 10, 2019 At 12:08 pm
Any person involved in this cover up should serve very stiff prison sentences and it should be in a tough prison not one where the house the white collar crimes but a real prison.
Raymond Charron December 10, 2019 At 12:55 pm
There's more than one way to skin a cat. Send info by secret mail to Trump.
THERE NEEDS TO BE WARRANTS OUT OF THE DEEP STATE NOW.-ENOUGH DAMAGE HAS BEEN DONE BY THEM. THEY RE CRIMINALS. AND NEED TO BE THROWN IN PRISON.!!! THEY HAVE ONLY WORKED FOR THEMSELVES NOT THE AMERICAN PEOPLE. BESIDE WE KNOW THEIR TRUE AGENDA IS AND IT NEEDS TO BE DESTROYED FOR OUR SAKE!!!!
Aaron December 10, 2019 At 8:56 pm
Time to expose the Projecto-crats. Unclear why Chairman Burr and Chairman Graham haven't been holding hearings in the Senate since this all started. Potentially they have streams of foreign influence and kickbacks they need to protect. Meanwhile nervous Nancy hands out subpoenas like girl scout cookies. Continue to stand with the most transparent President in our time. 4 more years !!!
Big Ed December 10, 2019 At 10:37 pm
Odd isn't it? The ambassador who refused to give travel VISAs to Ukrainians who wanted to come to the US to give files on corruption to our DoJ was none other than Marie Yovanovitch (Schiff's star witness in the Ukrainian quid pro quo impeachment hearings). Marie is very angry with Trump for firing her, but as it happens, she was neck deep in the Ukrainian corruption which Trump was attempting to ferret out.
They will never do it in a criminal investigation but if they were to follow the leads it would all lead to george soros. The man has to much money and influence to ever be put in jail which is where he should be.
Thousands of years of breeding have not been kind to doggy joints … but there is a solution. How do you know if your dog is suffering? They can't exactly tell you where it hurts, but there are important signs of pain you should look for. Does your dog display any of these painful symptoms?.....
4 Signs Your Dog is Suffering from Joint Pain
Introductory credit card rates sounds great until your once "good deal" turns very, very bad. Oftentimes, the best and only way out of credit card hell is a personal loan specifically earmarked for debt consolidation purposes. Once you get approved for a debt consolidation loan, you can literally pay off your credit cards with a.....
Smash BAD Credit Card Interest Rates Like This

redpajama_set_name: RedPajamaCommonCrawl


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Derrick Johnson Elected President and CEO of NAACP
Obamacare the Hot Topic at Pumps, Pearls & Politics Forum Nov. 5
Topdog/Underdog begins Nov. 2 at the Arsht Center
Zoetic Stage and
the Adrienne Arsht Center for the Performing Arts of Miami-Dade County
By Suzan-Lori Parks
A Pulitzer Prize-winning dark comedy about brotherhood and family identity
Opens the 2017-2018 season for Zoetic Stage and
the Arsht Center's Theater Up Close Series
Zoetic Stage and the Adrienne Arsht Center for the Performing Arts of Miami-Dade County are proud to present TOPDOG/UNDERDOG, a Pulitzer Prize-winning dark comedy by Suzan-Lori Parks. Playing November 2 – November 19, 2017 in the intimate Carnival Studio Theater (Ziff Ballet Opera House), TOPDOG/UNDERDOG launches Zoetic Stage's 2017-2018 season at the Arsht Center as part of the Center's highly-acclaimed Theater Up Close Series.
Winner of the Pulitzer Prize for Drama, TOPDOG/UNDERDOG is a darkly comic tale of brotherhood and family identity. The play tells the story of Lincoln (Eddie Brown) and Booth (Marckenson Charles), two African-American brothers (whose names were given to them as a joke) coping with women, work, poverty, gambling, racism, and their troubled upbringings. Haunted by the past, the brothers are forced to confront the shattering reality of their future.
Zoetic Stage was founded in 2010 to create fresh, bold interpretations of contemporary plays and musicals, and is dedicated to enhancing South Florida's national artistic profile by producing regional premieres and developing new works to become part of the American stage repertoire. The company will co-present three more exciting productions with the Arsht Center in the 2017-2018 season. Zoetic Stage's 7th anniversary season will continue with the world premiere of Wrongful Death and Other Circus Acts (January 18 – February 4, 2018), the latest work by Christopher Demos-Brown, award-winning writer of Stripped, American Son and Fear Up Harsh; the South Florida premiere of Dancing Lessons (March 8 – March 25, 2018), Mark St. Germain's poignant and hilarious romantic comedy; and the South Florida premiere of the five-time Tony Award-winning musical, Fun Home (April 12 – May 13, 2018).
Tickets to TOPDOG/UNDERDOG may be purchased through the Adrienne Arsht Center Box Office by calling (305) 949-6722, or online at www.arshtcenter.org.
Posted by Va-Va on Monday, October 30, 2017 at 02:43 PM in Culture, Events, Lifestyle & Entertainment, The Arts | Permalink | Comments (0)


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John's Horror Corner: Annabelle: Creation (2017), super creepy, super jumpy, super evil, and a fine addition to The Conjuring Universe.
tags: Annabelle, Creation, demonic possession, doll movie, evil doll, sequel, the conjuring universe
by John Leavengood
MY CALL: Very jumpy, very creepy, and very much more worthy of your time than part 1! MORE MOVIES LIKE Annabelle: Creation: Well, The Conjuring (2013; podcast discussion of The Conjuring 2), Annabelle (2014; podcast discussion of Annabelle) and The Conjuring 2 (2016) round out The Conjuring Universe. For more evil doll movies one may venture Dead Silence (2007), Dolls (1987), Dolly Dearest (1981) Puppet Master 1-5 (1989-1994), The Boy (2016), Child's Play (1988), Curse of Chucky (2013) and even Poltergeist (1982; that evil clown was twisted).
Twelve years after the tragic loss of their daughter Bee (Samara Lee; The Last Witch Hunter), doll-maker Samuel (Anthony LaPaglia; Innocent Blood, So I Married an Axe Murderer) and his now ailing wife Esther (Miranda Otto; War of the Worlds, What Lies Beneath) agree to offer their home as an orphanage for a nun (Stephanie Sigman; Narcos) and six girls. Linda (Lulu Wilson; Ouija: Origin of Evil, Deliver Us from Evil) and her friend are drawn to a doll hidden away in Bee's bedroom and…well, you know…there's an evil doll, demonic possession…bad stuff happens.
The Conjuring Universe SIDEBAR: This has been labeled "the next chapter in The Conjuring Universe," and a Conjuring movie is exactly what this feels like. Well, The Conjuring (2013) was so outstanding that Annabelle (2014) couldn't be expected to measure up. But falling far below that, evil doll movies practically make themselves yet Annabelle was an absolutely incompetent horror film that should disappoint fans of the genre whether they were birthed in the era of serious slashers, classic Hammer releases, or campy 80s slapstick gore-fests. The only way Annabelle made it to the big screen was by riding the tidal wave of hype created by its connection to The Conjuring. Then along came The Conjuring 2 (2016)—which felt a lot like Insidious "Chapter 4"—which was clearly made more for the fans than the critics as it focused more on being excitingly jump-scary than on standard merits or sleek plotiness. This sequel introduced The Nun (i.e., the demon Valek) and gave a fine nod to Annabelle. Following suit, Creation offers a mysterious wink harbingering the upcoming Nun film (same writer as Creation) and then finishes transitioning us directly into the opening scene of Annabelle (2014).
I wasn't at all surprised to learn this was directed by David F. Sandberg (Lights Out), as it felt very much like Lights Out (2016) meets The Conjuring 2 (2016) in terms of scare-staging, the use of darkness and flickering lights, the super twitchy monster manifestations, and the roller-coasting dozens of jump scares. I should repeat part of that: DOZENS of jump scares. Holding together far more soundly and satisfyingly than Annabelle (2014), this plot still wasn't terribly substantial. It had "just enough," with the story feeling neither deep nor shallow, and quite familiar without being phoned in or rehashed. But, then again, we are in The Conjuring Universe and the conduits by which evil manifests in our present cinescape seem to follow the same rules or patterns as we have now witnessed in a total of four films. It's the kind of familiarity we find in a Freddy, Jason, Pinhead or Myers sequel…we know the general rules, but we also expect some new angle in each new film to come.
Now I just called this "familiar." But, make no mistake, it's quite exciting after a somewhat slow introduction to our premise. But then becomes exciting if you enjoy jump scares. As I mentioned earlier, this film thrives on them. You'll hear something creepy, stare into a pitch-black hallway or doorway for 8 seconds, and press your head into your seat to brace yourself for the inevitable incoming scare. This may bother folks looking for the next horror Oscar contender, but people just looking for a fun date night or a great popcorn horror will be in for a good time. In fact, I'd call this outstanding popcorn horror.
What gore we get is good, the acting is all on point, the demon monster effects were VERY creepy, and despite the high frequency of jump-scares there were some seriously legitimate scares as well. I really appreciated that all that this film tried to do; give us a prequel, connect adequately to both The Conjuring (2013) and Annabelle (2014), provide a semblance of continuity, and serve as a stand-alone horror film. And, perhaps its best quality, it never really felt like an evil doll movie. It felt more like a mix between a cursed object and a demonic haunting/possession/presence. It certainly kept me on my toes.
Overall, I'd say I was quite pleased. I'll certainly buy it and, due to the sheer joy derived from all the jump-scares, I look forward to sharing this with someone who hasn't yet seen it.
from → John Leavengood, John's Horror Corner, Movies
← MFF Special: Does the Number of Splits in a JCVD Film Impact the Critical and Audience Scores?
John's Horror Corner: The Barn (2016), an excellent case study in practical effects-driven microbudget horror. →
John's Horror Corner INDEX: a list of all my horror reviews by movie release date | Movies, Films & Flix
John's Horror Corner: Cult of Chucky (2017), from the 1988 classic to the guilty pleasure sequels, I continue to enjoy this evil doll franchise! | Movies, Films & Flix
The Six Best Horror Films of 2017 | Movies, Films & Flix
The MFF Podcast #108: The Best Horror Films of 2017 | Movies, Films & Flix
The MFF Podcast #113: Elise, her Demons and the Insidious Franchise | Movies, Films & Flix
John's Horror Corner: Satan's Slaves (2017; aka Pengabdi Setan), the Shudder Original remake about an Indonesian haunting and a Satanic cult. | Movies, Films & Flix
John's Horror Corner: The Silence (2019), the Netflix Original that combines A Quiet Place (2018) and Piranha (2010). | Movies, Films & Flix
John's Horror Corner: Dolls (1987), a heavy dose of 80s-nostalgic murderous stop-motion demon dolls from goretastic director Stuart Gordon. | Movies, Films & Flix
John's Horror Corner: The Curse of La Llorona (2019), watering down the Conjuring Universe with ill-executed the Mexican folklore of the Weeping Woman. | Movies, Films & Flix
John's Horror Corner: Child's Play (2019), the fun reboot of the 1988 classic evil doll franchise that we deserve! | Movies, Films & Flix
John's Horror Corner: Child's Play (1988), the classic evil doll movie introducing us to Chucky and Brad Dourif's menace! | Movies, Films & Flix
John's Horror Corner: Annabelle Comes Home (2019), an entertaining but middle-of-the-road contribution to The Conjuring Universe. | Movies, Films & Flix
John's Horror Corner: Child's Play 2 (1990), an inferior evil doll sequel that still manages to entertain, especially with its melty finale. | Movies, Films & Flix
John's Horror Corner: Child's Play 3 (1991), Chucky goes to military school and breaks his Voodoo rules in this serviceable sequel. | Movies, Films & Flix


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Q: How i can scrape data from website in android studio? How do I scrape data from a website using selenium or selendroid in Android studio?
I used jsoup but I need to wait for the progress to finish before scraping the data.

redpajama_set_name: RedPajamaStackExchange


text:
Roy Díaz González  (born 1953) is a former world-class badminton player from Mexico. Something of a child prodigy in the sport, González began touring internationally at fourteen, the age at which he captured the first of his many Mexican national singles titles. He won the Belgian International men's doubles title at fifteen and the Swiss Open men's singles title at sixteen. By his late teens, in the early 1970s, González was competitive with the world's best players, but he never developed the penetrating power, or the deceptive wizardry, which might have allowed him to break through in badminton's biggest events. Nevertheless, he remained a respected and dangerous opponent on the world scene for over a decade, admired for his footwork, stamina, and touch. In 1977 he won men's singles at the first ever Pan-American Badminton Championships. González played in five Thomas Cup (men's international team) campaigns for Mexico, between 1970 and 1984, before finally losing a Thomas Cup singles match to another North American player. His advisor at the court was for a long time his father Dr. Jorge Díaz González.

References

Mexican male badminton players
1953 births
Living people

redpajama_set_name: RedPajamaWikipedia


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Relationships between fabric, sedimentary facies and stromatolite
Relationships between fabric, sedimentary facies and Selleck OICR-9429 Stromatolite morphologies indicate: that microbes played a role in local mediation of sediment deposition (leading to stromatolite
formation); the environmental forces that the microbes were subject to; the likely responsive strategies that microbes adopted; and the resultant effect on stromatolite morphology. As targeted, precise, geochemical and organic geochemical data are obtained in the Strelley Pool Formation, their interpretation is greatly constrained by their relationship with the fabrics and facies they are found in. The approach has proven useful not only in revealing new types Target Selective Inhibitor Library of evidence for the origin of the Strelley Pool Formation stromatolites, but also for generating principles that can be applied to other cases. Allwood A.C., Walter M.R., Kamber B.S., Tipifarnib Marshall C.P., Burch I.W., 2006. Stromatolite reef from the Early Archaean era of Australia. Nature, 44:714–718. E-mail: Abigail.C.[email protected]nasa.gov
Four Oxygen Reductases, Four Evolutionary Histories: Implications for the Emergence of Aerobic Respiration and Early Earth Atmosphere Celine Brochier-Armanet*1,3, Emmanuel Talla2,3, Simonetta Gribaldo*4 1Université de Provence Aix-Marseille I, France; 2Université de la Méditerranée Aix-Marseille II, France; 3Laboratoire de Chimie Bactérienne CNRS UPR9043, Marseille, France; 4Unité de Biologie Moléculaire chez les Extremophiles (BMGE), Institut Pasteur, Paris, France Understanding the origin and evolution of cellular processes is fundamental to understand how biological activity has shaped the history of our planet as well as its biota. Dimethyl sulfoxide We have investigated the distribution of the four types of oxygen reductases—the
key enzymes of aerobic respiratory chains, in all available complete archaeal and bacterial genomes, and analyzed their phylogeny. Our results show that each oxygen reductase type has a very different evolutionary history. However, one of them was already present prior to the divergence of Bacteria and Archaea, and was maintained throughout their subsequent diversification. Implications for the emergence of aerobic respiration and early earth atmosphere will be discussed. Titan: Exploring an Earth-Analogue A. Coustenis LESIA, Paris-Meudon Observatory, France Titan, Saturn's largest satellite was discovered in 1655 by Huygens. Much later, it was found to possess a substantial atmosphere by Kuiper in the 1940s. Titan is today still the only confirmed exobiotic environment known to us. It is also perhaps the most intriguing object in our Solar System.
bPercentage of positive studies
bPercentage of positive studies. NVP-BGJ398 purchase Apoptosis Li et al. [72] revealed that there was the dose-dependent effect of apoptosis in the N9 cells exposed to nano-TiO2 and the significant difference observed in 16 μg/ml TiO2 NPs-treated groups and this apoptosis might lead to the dysfunction of microregions. The study of Carmen et al. [10] reported that suspensions of TiO2 nanoparticles prepared in U937 cells culture medium at concentrations that covered a range
(0.005 to 4 mg/kg) induced apoptosis in 24 and 48 h. In contrast, Han et al. [33] results showed that the cell apoptosis was not influenced by the presence of nano-TiO2 at 50 to 200 μg/ml for 24 to 72 h. Different studies have different results and in this report on apoptosis, tests from ACY-1215 order cell models were summarized and we calculated the combined Smoothened Agonist effects of exposure to nano-TiO2. According to Table 4, there is a combined apoptosis effects at different times and dosages and it gave us a clue for apoptosis induced by exposure to nano-TiO2, although
the number of studies was small. Inflammation To assess inflammation by nanomaterials immunotoxicity, the production of inflammatory markers such as the chemokines interleukin (IL)-8, IL-6, or TNF-α was usually measured in cell culture supernatants using enzyme-linked immunosorbant assay. In this study, we realized that the percentage of positive study is lower and no dose- and time-dependent relationships were found, and this may due to the small number
SPTLC1 of studies available. Future studies determining inflammatory combined effects of nano-TiO2 need go deep into (Table 5) these aspects. Table 5 Inflammation and cytotoxicity in 24 h for the different doses Study dose (mg/ml) Inflammationa (h) Cytotoxicity at 24 ha (nm) ≤24 ≤48 Total Percentageb <10 10 to 20 21 to 40 40 to 100 Total Percentageb ≤0.005 0/1 0/2 0/3 0 0/2 1/6 0/3 0/2 1/13 /7 ≤0.05 0/1 0/2 0/3 0 0/3 7/3 4/2 0/2 11/10 52 ≤0.5 1/1 1/1 2/2 50 2/2/ 5/2 5/2 0/2 12/8 60 ≤5 0/0 1/1 1/1 50 0/0 3/1 1/1 1/0 5/2 71 Total 1/3 2/6 3/9 – 2/7 16/12 10/8 1/6 29/33 47 Percentageb 25 25 25 – 22 57 56 14 – - aNumber of positive/negative studies. bPercentage of positive studies. Size dependency Particle dimension is recognized as being fundamental to their toxicity. This derives from the fact that NPs have been consistently demonstrated to be capable of eliciting more pronounced toxicity than their large (microparticulate) counterparts [73]. The size dependency of nano-TiO2 toxicity has been frequently demonstrated and appears to be applicable to a variety of nano-TiO2 forms from the cell model.
Microbiol Immunol 2009, 53:206–215 PubMedCrossRef 11 Beutin L, G
Microbiol TPCA-1 research buy Immunol 2009, 53:206–215.PubMedCrossRef 11. Beutin L, Geier D, Steinruck H, Zimmermann S, Scheutz F: Prevalence and some properties of verotoxin (Shiga-like toxin)-producing Escherichia coli in seven different species of healthy domestic animals.
J Clin Microbiol 1993, 31:2483–2488.PubMedCentralPubMed 12. Elder RO, Keen JE, Siragusa GR, Barkocy-Gallagher GA, Koohmaraie M, Laegreid WW: Correlation of enterohemorrhagic Escherichia coli O157 prevalence in feces, hides, and carcasses of beef cattle during processing. Proc Natl Acad Sci U S A 2000, 97:2999–3003.PubMedCentralPubMedCrossRef 13. Clark CG, Johnson ST, Easy RH, Campbell JL, Rodgers FG: PCR for selleck detection of cdt-III and the relative frequencies of Cytolethal distending toxin variant-producing
Escherichia coli isolates from humans and cattle. J Clin Microbiol 2002, 40:2671–2674.PubMedCentralPubMedCrossRef 14. da Silva Selleckchem DMXAA AS, da Silva LD: Investigation of putative CDT gene in Escherichia coli isolates from pigs with diarrhea. Vet Microbiol 2002, 89:195–199.PubMedCrossRef 15. Foster G, Ross HM, Pennycott TW, Hopkins GF, McLaren IM: Isolation of Escherichia coli O86:K61 producing cyto-lethal distending toxin from wild birds of the finch family. Lett Appl Microbiol 1998, 26:395–398.PubMedCrossRef 16. Mainil JG, Jacquemin E, Oswald E: Prevalence and identity of cdt-related sequences in necrotoxigenic Escherichia coli . Vet Microbiol 2003, 94:159–165.PubMedCrossRef 17. Friedrich AW, Lu S, Bielaszewska M, Prager R, Bruns P, Xu JG, Tschäpe H, Karch H: Cytolethal distending toxin in Escherichia coli O157:H7: spectrum of conservation, structure, and endothelial toxicity. J Clin Microbiol 2006, 44:1844–1846.PubMedCentralPubMedCrossRef 18. Abbott SL, O'Connor J, Robin T, Zimmer BL, Janda JM: Biochemical properties of a newly described Escherichia species, Escherichia albertii . J Clin Microbiol 2003, 41:4852–4854.PubMedCentralPubMedCrossRef 19. Ooka T, Seto K, Kawano K,
Kobayashi H, Etoh Y, Ichihara S, Kaneko A, Isobe J, Yamaguchi K, Horikawa K, Gomes TA, Linden A, Bardiau M, Mainil JG, Beutin L, Ogura Y, Hayashi T: Clinical significance of Escherichia albertii . Emerg Infec Dis 2012, 18:488–492.CrossRef 20. Pérès SY, Marchès O, Daigle F, Nougayrède JP, Herault F, Tasca C, De Rycke PJ34 HCl J, Oswald E: A new cytolethal distending toxin (CDT) from Escherichia coli producing CNF2 blocks HeLa cell division in G2/M phase. Mol Microbiol 1997, 24:1095–1107.PubMedCrossRef 21. Paton AW, Srimanote P, Talbot UM, Wang H, Paton JC: A new family of potent AB(5) cytotoxins produced by Shiga toxigenic Escherichia coli . J Exp Med 2004, 200:35–46.PubMedCentralPubMedCrossRef 22. Wu Y, Hinenoya A, Taguchi T, Nagita A, Shima K, Tsukamoto T, Sugimoto N, Asakura M, Yamasaki S: Distribution of virulence genes related to adhesins and toxins in shiga toxin-producing Escherichia coli strains isolated from healthy cattle and diarrheal patients in Japan.
91 Mbp), and megaplasmid pHG1 (0 45 Mbp); and the
genes f
91 Mbp), and megaplasmid pHG1 (0.45 Mbp); and the
genes for essential metabolisms and cellular functions are located on chromosome 1. The genome information has facilitated the genome-wide transcriptome analysis of this strain. Hitherto, transcriptome analyses of R. eutropha were performed using a DNA microarray technique. Peplinski et al. reported check details a comparison of the transcriptomes of wild-type strain H16 and the two PHA-negative strains in different growth phases based on competitive hybridization [17]. They observed significant differences in the Selleckchem MK-8931 transcription levels of a large number of genes in these strains, including genes involved in lipid metabolisms. However, the comparison of transcriptomes in the exponential growth and P(3HB) biosynthesis phases of R. eutropha was unclear. Brigham et al. carried out a transcriptomic comparison of R. eutropha
H16 cells grown in fructose- and trioleate-containing media, and identified two gene clusters responsible for β-oxidation [18]. Hybridization-based DNA microarray methods have mainly been MLN2238 clinical trial used for global transcriptome analysis; however, these methods exhibit a relatively low dynamic range for detecting transcription because of two reasons. One is a high level of noise caused by cross-hybridization, and the other is saturation and poor sensitivity at very high and low transcriptional levels, respectively [19]. Recently, the direct sequencing of complementary DNA generated from RNA (RNA-seq) based on high-throughput DNA sequencing technology was often used to study RNA population within the cells [20]. Many studies have demonstrated that RNA-seq has several advantages over the previous microarray methods used for transcriptional analysis, including a larger dynamic range, lower background noise, and greater sensitivity [21]. In addition, this technique enables comparison of the transcription levels of different genes in the same sample.
Although RNA-seq was initially difficult very to apply to bacterial cells without poly-A tails in their mRNA, enrichment of the mRNA by rRNA pulldown and great improvement in the sequencing depth of the recent sequencer can overcome this problem [21]. In this study, we applied RNA-seq to profile and quantify the transcription levels of R. eutropha H16 genes in the growth, PHA biosynthesis, and stationary phases on fructose. We successfully detected a number of interesting transcriptomic changes that depended on the cellular phases. Recently, Brigham et al. carried out a microarray analysis of this strain in different phases, and identified the regulation of PHA biosynthesis by a stringent response [22]. Several of our results were consistent with those based on the microarray analysis as described below, and one of the interesting results was a significant induction of CBB cycle in the PHA production phase on fructose. Thus, we investigated the possibility of CO2 fixation during P(3HB) biosynthesis by R.
Therefore, we used a rather strict criterion for "normal hearing"
Therefore, we used a rather strict criterion for "normal hearing", and more specific criteria for the degree of the noise notch. The following audiogram categorization was applied to the audiometric thresholds per ear: Normal hearing (N): hearing threshold levels better than or equal to 15dB HL at all measured frequencies (i.e. 0.5, 1, 2, 3, 4, 6, 8 kHz). Notch moderate (NM): maximum threshold level of 3, 4, and 6 kHz between 15 and 20 dB poorer than the pure-tone average of thresholds at 0.5, 1 and 2 kHz and at least 10 dB poorer than the threshold
level at 8 kHz. This is similar to Niskar et al. (2001) criterion of a noise notch in adolescents. Notch profound (NP): similar to NM, but maximum threshold level of 3, 4, 6 kHz at least 25 dB poorer than the pure-tone
FK228 average of thresholds at 0.5, 1 and 2 kHz. Sloping loss (SL): I-BET151 maximum threshold level of 3, 4, 6 kHz at least 5 dB poorer than the pure-tone average of thresholds at 0.5, 1 and 2 kHz and threshold level at 8 kHz at least 5 dB poorer than the maximum threshold level at 3, 4, and 6 kHz. Flat loss (FL): audiograms which do not fall into the above mentioned categories, with no hearing thresholds exceeding 30dB at all measured frequencies. Rest (R): all audiograms that do not match the characteristics of the above described categories. The corresponding average audiograms are shown in Fig. 1. The average audiogram in the group "Rest" turned out to have a steeply sloping curve. Most ears fell in the "Normal hearing" category (230 ears, 48%). The other ears were approximately equally divided over the other categories Cediranib (AZD2171) (NM = 53 ears, 11%, NP = 41 ears, 9%, SL = 64 ears, 13%, FL = 57 ears, 12%, R = 35 ears, 7%). If present, notches were mostly found at 6 kHz. Fig. 1 Musicians average audiograms according to the criteria for normal hearing (N), notch moderate (NM), notch profound (NP), sloping loss (SL), flat loss (FL), and a rest group (R) In the
"Normal hearing" category the average age of the ears was lowest (39.7 years), while it was highest in the "Sloping loss" category (52.2 years). For the category "Notch profound" (48.8 years) it was higher than for the category "Notch moderate" (45.1 years). A direct comparison of the distribution of audiometric categories across instruments groups could only be done with some caution, as there were large variations in the number of musicians in the instrument subgroups. However, when considering only the large groups, HS, LS, WW and BW, 40–52% of each of these groups fell into the audiogram category "Normal Hearing". The AZD3965 in vivo percentages did not differ significantly (χ 2(3) = 2, p = 0.57). Hearing loss with sloping curves (SL) was found less among the brass wind players (2 ears, 3%) than in the other groups (HS = 28 ears, 14%, LS = 16 ears, 20%, and WW = 13 ears, 13%, χ 2(3) = 11.9, p = 0.007).
Conversely, a
Conversely, a 4EGI-1 supplier high growth rate, the ability to grow in adherence as in compact lesions and the lack of pigmentary activity (as a consequence of the environment acidification due to the high levels of glycolytic activity -the Warburg effect-), are typical of those melanomas
adapted to grow in highly hypoxic condition of fast growing metastases. In this perspective the discussed results are consistent with the hypothesis of a more differentiated phenotype. Indeed following E5 expression and the restoration of a near neutral pH, in addition to the correct maturation of tyrosinase, a global re-organization of the endocellular trafficking occurs. Such a reorganization permits the adequate processing of the many pigmentary proteins through several different pathways and their correct cooperation into the multi-step process of pigment deposition. As a whole these data stand against the hypothesis that the E5 alkalinisation of cellular pH takes place through the subversion of endocellular trafficking, which is on the contrary restored, at least as far as melanogenesis is concerned. Conversely they support the view that the E5 protein, once expressed in an intact human cell, directly or indirectly modulates V-ATPase proton pump with
a wide range of orchestrated functional consequences. Finally restoration Cell Cycle inhibitor of the melanogenic phenotype is associated with a clear elevation of cell reducing activity, consistent with a partially re-differentiated phenotype. Once again this result is in line with the hypothesis of a close linkage between the global melanoma phenotype and the cell metabolism which impacts on growth abilities, pathways activation and pigment deposition [36, 37]. Being the anaplastic phenotype of melanomas associated with a less favourable clinical outcome and a more severe prognosis [40], we next wondered whether such a reversion could have an impact on response to chemotherapeutic agents. In this work we showed that following the inhibition of V-ATPase by HPV16-E5
the whole melanin synthesis pathway 4��8C is restored in amelanotic melanoma lines and accordingly these cells appear more responsive to dopamine-mimetic pro-drugs, whose toxicity is related to their oxidation into toxic intermediates i.e. quinones, by tyrosinase-catalyzed reactions. In addition, tyrosinase reactivation is also selleckchem linked with an increased sensitivity to drugs interacting with other related pathways, as shown by the case of BSO, a GSH depleting drug via the gamma-glutamyl-cysteine synthetase inhibition. Since GSH is a major defence against toxic quinone intermediates through the production of conjugates, GSH depletion results in a severe cell death selectively in those cells where active melanogenesis is present. In conclusion the expression of the HPV16-E5 oncogene proved able to (partially) revert the malignant phenotype of amelanotic melanomas to a less aggressive, drug responsive state.
PCC 7120 under N 2 fixing conditions J Proteome Res 2007,6(2):62
PCC 7120 under N 2 fixing conditions. J Proteome Res 2007,6(2):621–635.selleckchem PubMedCrossRef 34. Axelsson R, Lindblad P: Transcriptional regulation of Nostoc hydrogenases: effects of oxygen, hydrogen, and nickel. Appl Environ Microbiol 2002,68(1):444–447.PubMedCrossRef 35. Weyman PD, Pratte B, Thiel T: Transcription of hupSL in Anabaena variabilis ATCC 29413 is regulated by NtcA and not by hydrogen. Appl Environ Microbiol
2008,74(7):2103–2110.PubMedCrossRef 36. Lindberg P: Cyanobacterial Hydrogen Metabolism – Upptake Hydrogenase and Hydrogen Production by Nitrogenase in Filamentous SB202190 molecular weight Cyanobacteria. PhD thesis Uppsala: Uppsala University 2003. 37. Yoshino F, Ikeda H, Masukawa H, Sakurai H: High photobiological hydrogen production activity of a Nostoc sp. PCC 7422 uptake hydrogenase-deficient mutant with high nitrogenase activity. Marine Biotechnol 2007,9(1):101–112.CrossRef 38. Leitao E, Oxelfelt F, Oliveira P, Moradas-Ferreira P, Tamagnini P: Analysis of the hupSL operon of the nonheterocystous cyanobacterium
Lyngbya majuscula CCAP 1446/4: regulation of transcription and expression under a light-dark regimen. Appl Environ Microbiol 2005,71(8):4567–4576.PubMedCrossRef 39. Oliveira P, Leitao E, Tamagnini P, Moradas-Ferreira P, Oxelfelt F: Characterization and transcriptional analysis of hupSLW in Gloeothece sp. ATCC 27152: an uptake hydrogenase from a unicellular cyanobacterium. Microbiol 2004,150(11):3647–3655.CrossRef 40. Rippka R, Neilson A, Kunisawa R, Cohen-Bazire G: Nitrogen fixation by unicellular blue-green algae. Arch Mikrobiol
check details 1971,76(4):341–348.PubMedCrossRef 41. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual USA: Cold Spring Harbour Laboratory Press 1989. 42. Meeks JC, Elhai J, Thiel T, Potts M, Larimer F, Lamerdin J, Predki P, Atlas R: An overview of the genome of Nostoc punctiforme , a multicellular, symbiotic cyanobacterium. Photosynth Res 2001,70(1):85–106.PubMedCrossRef Ribonucleotide reductase 43. Sjöholm J, Oliveira P, Lindblad P: Transcription and Regulation of the Bidirectional Hydrogenase in the Cyanobacterium Nostoc sp. Strain PCC 7120. Appl Environ Microbiol 2007,73(17):5435–5446.PubMedCrossRef 44. Oliveira P, Lindblad P: An AbrB-Like Protein Regulates the Expression of the Bidirectional Hydrogenase in Synechocystis sp. Strain PCC 6803. J Bacteriol 2008,190(3):1011–1019.PubMedCrossRef 45. Muro-Pastor AM, Valladares A, Flores E, Herrero A: The hetC Gene Is a Direct Target of the NtcA Transcriptional Regulator in Cyanobacterial Heterocyst Development. J Bacteriol 1999,181(21):6664–6669.PubMed 46. Montesinos ML, Muro-Pastor AM, Herrero A, Flores E: Ammonium/Methylammonium Permeases of a Cyanobacterium. Identification and analysis of three nitrogen-regulated amt genes in Synechocystis sp. PCC 6803. J Biol Chem 1998,273(47):31463–31470.PubMedCrossRef 47. Argueta C, Yuksek K, Summers M: Construction and use of GFP reporter vectors for analysis of cell-type-specific gene expression in Nostoc punctiforme.
The carboxy terminus of CpcA contained a region similar to the ba
The carboxy terminus of CpcA contained a region similar to the basic region of bZIP superfamily of transcription factors with strong sequence similarity to that of the homolog in A. fumigatus or A. nidulans (Figure 2C). buy PFT�� In contrast with the Aspergillus homologs, the leucine zipper region contained three conserved leucine residues characteristic of a leucine zipper L-x(6)-L-x(6)-L-x(6)-L (Figure 2C). As expected for a protein with a transcription factor domain, CpcA was predicted by PSORT II to be localised in the nucleus (69.6% probability) and SignalP did not predict the presence of an N-terminal signal peptide (98.7% probability). In A. nidulans, cpcA transcription is autoregulated via cross pathway
regulatory elements (CPRE) 5′ TGA-(C/G)-TCA-3′ in the cpcA promoter [13]. Point mutations in CPRE lead to low levels of cpcA transcripts and CpcA protein, when amino acids are limited. Such an element matching the consensus was present on the minus strand in the promoter region of L. maculans cpcA (-698 to -703). Figure 2 A) The cpcA locus of Leptosphaeria maculans. The conserved leucine zipper region at the C-terminus of cpcA is dark grey. The open boxes indicate the upstream Open Reading Frames uORF1 and uORF2 in the 5′ leader region. The black dot preceding them represents the putative cross-pathway control element (CPRE) whose sequence is 5′TGACTCA3′. B) Alignment
of the deduced amino acid sequence of uORF2 with counterparts in the leader sequences of Aspergillus Blasticidin S manufacturer fumigatus (Af) cpcA (GenBank XP_751584.1) and A. nidulans (An) cpcA (GenBank
AF302935). Black boxes with white text denote amino acids identical in two of the three fungal species. Grey boxes with white Methocarbamol text mark conserved changes. Gaps are introduced to optimize alignment. C) Alignment of the deduced amino acid sequence of the C-terminus conserved leucine zipper region with that of A. fumigatus CpcA and A. nidulans CpcA. The thick black line denotes the bZIP transcription factors basic domain signature (PS00036). Asterisks mark positions where conserved leucine residues characteristic of a leucine zipper (L-x(6)-L-x(6)-L-x(6)-L) should be found. Role of CpcA in Selleck CX-6258 sirodesmin PL production in L. maculans Although insertion of the T-DNA downstream of cpcA in mutant GTA7 reduced the transcript size by 127 bp, it did not reduce transcript levels of cpcA compared to those of the wild type (data not shown). Since the efficiency of gene disruption in L. maculans is very low, RNA mediated silencing was exploited to develop an isolate with extremely low levels of cpcA transcripts in order to study the effect of cpcA on sirodesmin PL production. Several putatively-silenced transformants were analysed and one, cpcA-sil, with 10% transcript level of that in wild type, as seen by q RT-PCR analysis, was chosen for further analysis (data not shown).
Fresh antibiotic stock solutions (10 mg/ml) were made for every e
Fresh antibiotic stock solutions (10 mg/ml) were made for every experiment. Test tubes were inoculated PD-1/PD-L1 targets to an OD578 of 0.05 with over night cultures of the Roseobacter strains in MB at 30°C. The results represent the mean of
three independent experiments performed in duplicate. Amp, ampicillin; Carb, carbenicillin; Cm, chloramphenicol; Gm, gentamicin; Kan, kanamycin; Spec, spectinomycin; Strep, streptomycin; Tc, tetracycline All tested species showed different susceptibilities to the antibiotics (Table 2). As expected, the seven D. shibae strains followed the same trend, with slight variations. They were all resistant to the β-lactam antibiotics ampicillin and carbenicillin. The level of tolerance to ampicillin was up to 500 μg/ml. The Phaeobacter strains, R. denitrificans and R. litoralis also showed resistance to ampicillin, whereas, in contrast to D.
shibae, they were sensitive to carbenicillin. Initially, we hypothesised, that the unexpected high ampicillin tolerance might occur due to instability of this antibiotic. It has been CDK inhibitor reported that ampicillin lost 28% of activity after 24 h at room temperature [30]. However, control experiments with the E. coli strain DH5α revealed complete activity of ampicillin even after incubation for five days at 30°C (data not shown). Analysing the annotated genomes of the strains by BLAST search and functional predictions (for details see Methods section), we identified genes encoding for β-lactamases, indicating that they are widespread over the Roseobacter clade. They were also found in R. denitrificans,
R. litoralis, P. gallaeciensis, O. indolifex and D. shibae. For the latter strain, three β-lactamases encoding genes were identified [using ROSY; [12]]. Thus, the inactivation of the antibiotics via degradation by β-lactamases seems to be an intrinsic resistance mechanism. Susceptibility C-X-C chemokine receptor type 7 (CXCR-7) of the Roseobacter strains differed towards the four tested aminoglycosides. R. denitrificans showed no susceptibility to all tested aminoglycosides. In contrast R. litoralis and P. gallaeciensis were sensitive to this group of antibiotics. Growth of P. inhibens was inhibited by high learn more concentrations of kanamycin, but the bacterium reacted very sensitive to spectinomycin and gentamicin. The D. shibae strains were resistant to kanamycin, but relatively sensitive to the three other aminoglycosides. O. indolifex was susceptible to all aminoglycosides. The resistance to the aminoglycoside gentamicin was already reported by Shiba [1991] as one of the characteristic properties of R. denitrificans. The corresponding genome exhibits a gene encoding for a putative aminoglycoside phosphotransferase, a type of enzyme inactivating aminoglycosides via modification [using IMG; [35], and ROSY; [12]].
Conversely, Buckley et al , [13] showed whey
Conversely, Buckley et al., [13] showed whey
protein hydrolysate ingestion in the days following an intense exercise bout (100 maximal knee extensions of the knee extensors) improved check details muscle strength recovery. The authors suggested that the use of partially hydrolysed (pre-digested) form of whey protein isolate may provide quicker delivery of amino acids to the muscle, and ultimately, more rapid recovery of force-generating capacity following muscle injury. The administration of whole proteins in the study by White et al. [12], may explain the lack of improvement in force recovery following damage. Furthermore, only a single dose was given to participants, whereas Buckley et al. [13] continued supplementation following the exercise bout and during the recovery period.
It could be suggested that for optimal ergogenic effects and recovery within the muscle, a hydrolysed form of whey see more protein (or free amino acids) needs to be ingested both immediately following the exercise bout, and in the days during recovery. However, this concept, particularly with eccentric contractions, has not been extensively investigated, as Buckley et al. [13] only followed recovery for 24 hours post-exercise. this website As such, whether the effects observed were related to muscle damage/regeneration, or simply faster recovery from fatigue, are difficult to determine. Jackman and colleagues [14] supplemented a controlled diet with BCAA and ameliorated the soreness following eccentric exercise. While they did not observe changes in strength measurements, ingestion was on the day of damage and for another 3 days afterwards, rather than for the whole regeneration process. In our previous study [15], ingestion of creatine monohydrate prior to and following a resistance exercise session indicated a possible attenuation of the amount of damage, and an increase in the rate of functional GBA3 recovery,
compared to a CHO placebo. Similarly, in the current study, given the equivocal data on protein supplementation and muscle recovery, we were interested in establishing whether a commercially available protein supplement can improve recovery from exercise-induced muscle damage, and thus used a CHO placebo as the comparison group. Thus, we supplemented the diet of a group of participants with a hydrolyzed whey protein isolate for 14 days during recovery from an identical resistance training session as used in our previous study [15]. We hypothesized that supplementation with hydrolyzed whey protein isolate will accelerate muscle strength recovery compared to an iso-energetic CHO control after a single bout of eccentric exercise. Methods Participants Seventeen healthy, untrained males (23 ± 5 yrs, 180 ± 6 cm, 80 ± 11 kg) volunteered for this study. Descriptive characteristics of the participants are presented in Table 1. Participants fulfilled the inclusion criteria as described in our previous study [15].


The tile is grouted! And I am surprised at how much I love it!
It's not magic, or made of fairy dust… (which is what I really wanted.) But for something I can scrub and disinfect and never think about sealing or etching or the other 97,000 issues you have to consider with marble… I love it.
My advice about choosing tile.
My frustration trying to find something I loved.
I know you've been struggling with this choice…. but YOU DID GOOD! I think it looks "magical" indeed. Seriously, I think you'll probably love it more and more every day. Congrats on your new and almost finished floor. If you already mention this… sorry to ask… but what is it exactly? What type, I mean. Ceramic, marble, etc. It's classy!
I'm confused. I think my RSS reader fed me your posts in the wrong order. Didn't I just comment on your post about not knowing what type of tile to us in this bathroom? Oy. Anyway, sorry to be out of step. I think it looks great, by the way. It seems to meet all your functional and aesthetic needs.
Probably your reader… although anyone could be confused, I've written way too much about tile.
It does feel functional… at least as far as assuaging my inner grout freak.
Hello, I have to say your bathroom looks fantastic. Quick question about the tile..I have been shopping around for marble look alike and seemed to have found one (porcelanosa carerra) however yours looks awesome as well. Is your tile completely smooth as in mirror smooth? I've noticed that a lot of marble look tiles look great until the lights hit them and you can see slight "ripples" …I guess the best description I have is the texture of walls – roller ripples… The porcelanosa tile is completely smooth just like polished marble. How is the peronda? Thanks in advance.
My tile is mirror smooth. I know exactly what you mean about some of them being textured on closer inspection… Mine has no ripples or anything.
I looked at the porcelanosa. I *think* I remember it because I could have gotten it in 22" or 24"?? Which I would have loved… so assuming I'm remembering correctly I really liked it. It was almost exactly what I wanted. Except that it had a creamier, more yellow base tint. Which didn't work for me.
PLUS, if you're not using subway tile on the walls, it may not matter to you. I love the true grey of real carrara, and when I laid out my options next to a bright-white subway tile, I noticed shade differences that I might not have otherwise.
THANK YOU!!! That's exactly what I needed to hear. I'll have to check this tile out as well before committing… The store you bought it from wouldn't happened to be "Magic Floors" on Franklin Mills Blvd, would it? I sure hopes cause that is my next and final stop. Thanks again for the reply.
I got it at a small shop in NJ… not too far from the Ben Franklin, so if you don't have any luck in Franklin Mills, and you have the energy for another trip… let me know and I'll look up their info. GOOD LUCK!!
Yes please send me the info. I'm actually in nj (and looked in so many stores north and south nj -this pa store was going to be the last one) but rather go to the store where you bought yours from first. Thanks so much.
They were really nice to deal with. When we decided for sure, they were able to order it for us by the next day… I think they have another, larger store somewhere in PA with a warehouse.
I hope you like it! I will feel bad for sending you on a wild goose chase, if you don't!!!
I absolutely ADORE that someone felt the need to put masking tape on the joiner piece that says "no step".
LOL… I know, Paul is nothing if not thorough.
Finally! Someone who GETS it! We built our home – which I know should be easier than remodeling, but it was literally chaos and insanity over little things! I was utterly obsessed over crystal knobs in the master bath. I wanted a crystal chandelier and knobs and as much crystal as could possibly fit in that one perfect room. My husband SELLS knobs. He builds cabinets for a living. His brother (who owns the shop with him) could not possibly fathom why I was out looking in shops and online and every.possible.place.in.earth for a knob that had to be a particular color crystal and back and finish when they had knobs for FREE! The ones they stock are nice. Pretty. They are used everyday in houses that cost 10 times what ours does. But they were not crystal!!!
But when a guest comes over and happens to go in that master bath – they almost always remark – hey cool knobs!
Victoria, simply an amazing job in all of the projects, not just the bathroom! I found your blog while on the search for carrara like tiles and will be going with the perdona I think for our master.
Right now we are in the middle of a half bath reno and are laying the real deal, bianco gioia 12×12 that I got for a song at the local granite yard. After making batches of poultice to draw out stains and sealing them 3 times before we even laid the tiles I know I'm going for faux marble in the master!
My dad, who has a good bit of tiling experience, is laying the 12 x 12 for me this weekend and has remarked that it is incredibly more difficult than a 6×6 to get the tile level in all planes. I can't bear to tell him about the possible upcoming 18 x 18 tile. Did your saint of a husband lay the bathroom floor himself or did you hire it out? Any tips for laying a tile that size?
The danger of this post is that it's making me rethink my bathroom flooring choice. If I spend the next three years shopping for the perfect marble tile, I will blame you.
And then send you pictures.
Thank you SO much for your numerous posts about your bathroom tile. I was looking for the exact same thing. After almost settling on another tile I saw this post and decided to consider it. Today I went and picked it up and it's PERFECT!!! I love it I love it I love it. I can't say thank you enough!!!!! Okay, just one more time. THAAAAANKKKKSSSSSSS!!!
No, thank YOU…. For validating my decision to dedicate a huge amount of time/energy/driving to searching for floor covering.
I am in the process of adding a new 5×9 bathroom. I, too, really want a polished hexagon carrera marble, but can't take the upkeep with a small child. I am most likely going to go the same route and get the Peronda Museum tile or something similiar. Do you still love it a few years later? How big is your bathroom and what size would you go up to if you found the right tile? Also, do you remember the grout color you used? Thanks so much! I really love your posts!
BTW, I bought the benary zinnias and I am growing them (at your suggestion) under lights. So far, 95% have germinated. I am so excited. Thank you for the great suggestions! Fingers crossed.
I do still love it. It is very neutral and bright… Not to mention SO easy to clean. I do not remember the name of the grout – it was before I understood that I must document ALL details. It is a very light gray/off-white.
Our bath is 9.5′ x 5.5′. I would have gone as large as humanly possible with the tile. If I could have put in a solid sheet, I would have.
Good luck with the flowers! don't forget to pinch them!
can you share your grout brand and color?
Funny thing is it's the same picture you are showing.
Ok I love your floor choice. I as well was going to do hexagon tiles but don't want to clean all the grout. My question to you is do you find the polished porcelain slippery?? I have a 3 and 6 year old and don't want to regret the tiles due to the slippery factor. Our floors will be heated so hoping this will help dry up any wet marks fast 🙂 Any feed back is much appreciated thank you!!!
Hey, I'm pasting a comment from another post rather than try to recap what she wrote… the COF was news to me, but I've since read about it and it's true.
P.S.: In event your grout is not an 'epoxy' type there are plenty of spray-on grout sealers on the market that can be applied after the grout has cured. Again, do your research and follow manufacturer's instructions re application.
Hi Victoria! I love your blog and I HATE blogs! You seem kind of amazing and I appreciate your work! Question—What was your threshold material and where did you find it?


As the original refrigeration experts since 1892, Marvel continues to uphold its hallmark standards for unrivaled craftsmanship, energy-efficient performance and signature features. These attributes are emblematic of the Marvel name and what continues to propel our reputation as the undercounter refrigeration brand to be desired.
Big Green Egg is now the world's largest producer and international distributor of the highest-quality ceramic cooking system. When you purchase an EGG, you know your investment is protected by a successful, experienced company with a worldwide reputation for best-in-class products and unmatched customer service – providing you with the confidence that comes from knowing that this company has been standing behind their products for over three decades!
Lynx has set the standard for design, innovation and engineering excellence, introducing proprietary technologies and custom features to ensure consumers have the ultimate Lynx experience.
The Sedona line of gas grills, barbecue islands and outdoor kitchen products are designed and manufactured by Lynx, a company long known for its high quality commercial kitchen products and luxury grills. The company introduced Sedona as an economical alternative for grilling enthusiasts looking for budget-friendly products that are still well-made and offer high performance and many convenient features. All the Sedona grills are made of 201 stainless steel. Heli-arch welding is used in the manufacturing process, which results in a seamless grill body free of gaps and seams.
Lynx has been manufacturing outdoor cooking products since 1996, with a commitment to raising outdoor cooking to a whole new level through the introduction of high quality products. The Sedona products are all made with premium materials and manufactured with the same high standards as all Lynx products are from the company's Southern California manufacturing facility.
For the wine enthusiast and entertaining we have an extensive line of Wine Chillers and Beverage Coolers. Our Wine Chillers are specifically designed to maintain the perfect conditions and showcase your valuable wine. Combined with our Beverage Coolers and Dispensers we offer a complete line of products for entertaining both indoors and outdoors.
Rasmussen is a four-generation family business that manufacturers Vented Gas Log Sets, ALTERNA® Contemporary Gas Fires, Chillbuster® Vent-free Gas Log Sets and Solaire® Infrared Grills, and distributes the Bromic line of radiant patio heaters.
Our sales, customer service and manufacturing teams share our true core values of quality and service. So whether you are a gas log dealer looking for a respected, quality manufacturer or a customer looking for the best price and quality, or perhaps even looking for something custom, we can help you find exactly what you're looking for in a gas log set or grilling unit.
Infratech indoor & outdoor heaters have a heated quartz element that emits a safe, clean wavelength of light that is only absorbed by solid objects, transferring heat directly to a person, table or floor rather than heating the air. For this reason, infrared heat can be distributed very evenly, and will not simply "blow away" in windy or drafty conditions. Infratech medium wave quartz element heaters emit a barely discernible, pleasing glow that will not affect the ambience of your gathering – unlike competitive short-wave or halogen electric heaters that produce a very harsh glare or bright-colored light.
Our founding team has a combined 45 years of experience in the industry, and we've used the experience to develop, test and make our products fantastic – because we all love what we do each and every single day. The same passion that we bring to the company is transferred to our customers through every product that we manufacture. One of the biggest complaints we heard before we started Blaze Grills was that while everyone wanted an outdoor kitchen, most people thought they would never be able to afford one. We believe that every person should truly be able to afford a luxurious outdoor living space without breaking the bank in the process. We make every product with the consumer in mind, combining a super high quality product with an affordable price point.
Born from a tradition of handmade skill and exacting quality, Challenger Designs is a unique company based on dedication to excellence and teamwork. And the results of that effort and pride show in every single aluminum product within our portfolio. Whether you are purchasing a Challenger aluminum cabinet or tool chest for a kitchen, grill cart, or bar for enjoyable living space, you are selecting the utmost in custom-made craftsmanship.
Modern-Aire Ventilating is a 3rd generation family business that, since 1956, has been producing the highest quality residential ventilation available. Whether you need a standard size liner or an Artisan crafted custom wall or island hood that will be the focal point of your kitchen space, Modern-Aire can create whatever you can imagine.
The experts at Paragon will help you in determining the perfect hood to effectively provide the ventilation you need with whisper quiet performance and impeccable styling.
Paragon and Modern-Aire together understand that your new hood for your kitchen or outdoor space is an integral part of the largest investment you will ever make. And as such we will work tirelessly to make sure your experience is smooth, seamless and superb!
Call or Email Paragon Distributing for a Dealer near you!
You don't have to be a 3rd generation, award-winning BBQ pitmaster to smoke your meats like one. Flame Boss™ lets you create mouth watering, delicious meat and fish dishes without the hassle of babysitting your smoker day and night.
Consider it cruise control for your smoker. It ramps up the heat. It lowers the heat. All you have to do is light the fire and set the control. No instructions necessary… but they're included just in case. Flame Boss takes it from there, keeping consistent, smoky goodness where it belongs – encircling your meat, poultry and fish.
Paragon Distributing is a southeastern regional distributor of high-end and affordable gas and charcoal grills, refrigerators, humidors, wine coolers, beverage coolers and ice makers.


Julia Montes is flattered about being called the next big dramatic star.
From doing minor roles as a child star, Julia's big break came last year when she was chosen by ABS-CBN management to play the mean character Clara in the remake of the popular '90s teleserye which starred Judy Ann Santos and Gladys Reyes. Since it's debut on the primetime block in October of last year, Mara Clara has become the most watched program across the country, and Julia's clashes with Kathryn Bernardo's character Mara has earned praise and gained a fan following.


As I did not receive any reply on my earlier post, re-posting my question in simplified way.
I have to configure SSO for SAPGUI for html from client browser. I have read the blogs and notes but still have some questions.
Questions: SSO between Web AS running on HP-UX 11.31 and Client PC on Win 7 using X.509 certificates would be possible without any third party product?
http://help.sap.com/saphelp_nwpi71/helpdata/en/b1/07dd3aeedb7445e10000000a114084/content.htm to configure SSO for SAPGUI for html, any other resource/blog that could help in this?
I recently used the X.509 certificates with no additional third-party product.
I used browser certificates in FF and actually openssl to create my demo certificates.


text:
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Paramedic in the Air Force?
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Home / Paramedic Schools / Paramedic Schools in Kansas
Paramedic Schools in Kansas
This article will provide you with a list of paramedic schools in Kansas where you can get admissions information, send applications, and graduate from in order to get a job as a working EMT Paramedic.
Do Note: This list now contains a collection of accredited and non-accredited paramedic programs.
Below, please click on a school to get admissions information on their healthcare programs:
Barton County Community College – Great Bend, KS
245 NE 30th Road
Great Bend, KS – 67530
Coffeyville Community College – Coffeyville, KS
Coffeyville, KS – 67337
Cowley County Community College – Winfield, KS
Winfield, KS – 67156
Garden City Community College – Garden City, KS
801 Campus Drive
Garden City, KS – 67846
Hutchinson Community College – Newton, KS
Emergency Medical Services – Paramedic Program
203 E Broadway
Johnson County Community College – Overland Park, KS
Department of Emergency Medical Science
12345 College Blvd.
Overland Park, KS – 66210
Kansas City Kansas Community College – Kansas City, KS
7250 State Avenue
Kansas City, KS – 66112
The accrediting organization for EMT Paramedic training education in the United States is the CoAEMSP (Committee on Accreditation of EMS Education Programs), which operates under the CAAHEP (Commission on Accreditation of Allied Health Education Programs). Beginning on January 1, 2013, graduation from an accredited paramedic program will be required for those seeking certification through the National Registry.
It's important to know that the career of EMTs and paramedics is on the rise. In fact, according to the U.S. Bureau of Labor Statistics (BLS), employment of EMTs and paramedics is expected to rise 23% from 2012 to 2022. That is much faster than the average for other career fields, and it should give EMS students peace of mind knowing that they are entering a career field that is on the rise, rather than on the decline.
Also, note that all EMTs and paramedics need to complete a postsecondary educational program, which essentially means that in order to work in EMS, you will need to complete a proper training and educational program following your graduation from high school (or GED equivalent).
As far as paramedic salary is concerned, the pay rate for EMTs and paramedics can vary quite a bit. This is mostly due to region, as someone working in Kansas is likely to may more money than a paramedic in the mid-west. Still, the median salary for EMTs and medics, according to the BLS, is $31,020.
Strong EMT and paramedic traits are essential to the job, as well. A lot of discussion goes into how much you can lift, or how educated or trained you are, but at the end of the day, patients (be it in Coffeyville, Hutchinson, Kansas City, etc) want to feel like you understand their pain and concerns, and that you care about their well being. And if you work in EMS, you really and truly should care about people.
And here, click on a school listed below to be taken directly to the college or university's official homepage:
Hutchinson Community College – Hutchinson, KS
You can discover more about online paramedic training, as well as local programs in your area, by checking out our helpful homepage.
If You Enjoyed This Article, We Recommend You Read:
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Paramedic Schools in Delaware
This article will provide you with a list of paramedic schools in Delaware where you can get admissions information, send applications, and graduate from in order to get a job as a working EMT Paramedic. Do Note: This list now contains a collection of accredited and non-accredited paramedic programs. Paramedic Schools in Delaware And here, click…
Read More Paramedic Schools in DelawareContinue
Paramedic Schools in Tennessee
This article will provide you with a list of paramedic schools in Tennessee where you can get admissions information, send applications, and graduate from in order to get a job as a working EMT Paramedic. Do Note: This list now contains a collection of accredited and non-accredited paramedic programs. Paramedic Schools in Tennessee Below, please click on…
Read More Paramedic Schools in TennesseeContinue
Paramedic Schools in Washington
This article will provide you with a list of paramedic schools in Washington where you can get admissions information, send applications, and graduate from in order to get a job as a working EMT Paramedic. Do Note: This list now contains a collection of accredited and non-accredited paramedic programs. Paramedic Schools in Washington Below, please click on…
Read More Paramedic Schools in WashingtonContinue
Paramedic Schools in Rhode Island
The accrediting organization for EMT Paramedic training education in the United States is the CoAEMSP (Committee on Accreditation of EMS Education Programs) that operates under the CAAHEP (Commission on Accreditation of Allied Health Education Programs). Beginning on January 1, 2013, graduation from an accredited paramedic program will be required for those seeking certification through the…
Read More Paramedic Schools in Rhode IslandContinue
Paramedic Schools in North Carolina
This article will provide you with a list of paramedic schools in North Carolina where you can get admissions information, send applications, and graduate from in order to get a job as a working EMT Paramedic. Do Note: This list now contains a collection of accredited and non-accredited paramedic programs. Paramedic Schools in North Carolina Below, please…
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Paramedic Schools in Arizona
This article will provide you with a list of paramedic schools in Arizona where you can get admissions information, send applications, and graduate from in order to get a job as a working EMT Paramedic. Do Note: This list now contains a collection of accredited and non-accredited paramedic programs. Below is a list of schools that…
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I recently wrote a feature article for eHealthcare Strategy & Trends magazine entitled, "How secure are your Web-based forms?" The article explored what happens after you press the submit button.
It turns out that lots of things can happen - many of them bad.
To clarify, "bad" is the wrong word. "Potential security weaknesses" is a better description. Once the information is whisked away it can be - and probably is - transmitted and stored in clear text.
To be fair, form security is not always needed. Take, for example, our website. Probably not a lot of sensitive or private information you'll be entering on a Web development firm Contact Us form.
But what about health sites, or banking sites, or ecommerce sites? In the context of these three types of sites, form security becomes quite important. It is these three reasons why we've been providing a continuum of form security which includes submission, notification and storage.
Submission is easy. It is handled by the ubiquitous SSL certificate. This encrypts information between the submitter and the Web site server. Cheap and reliable.
Notification (by which I mean how you learn a submission has been received on your site) gets a little trickier. The easiest way is for the Web server to dump the entirety of the form information into an email and send it to a staff member. This causes the form information to be sent in plain text, possibly touching several mail serving computers along the way. Then it arrives in someone's inbox and is stored in the mailbox of that user for who knows how long. All the time in plain text and visible to a host of machines and individuals.
A better way would be to simply notify of a form submission and provide a link back to the Web server to view it. That requires a login and password to view and, because you're viewing through the Web, it can be secured with that cheap and reliable SSL certificate.
To provide that notification, you need to store the form information in a database on the Web server. By default, database information is stored in clear text. As the final aspect of form security, we encrypt sensitive fields. This prevents someone from viewing these fields in the unlikely event that the database itself is compromised.
On Web sites, content has long been king. With Web forms, context is the real king. Every form must be examined for the possibility of drawing out sensitive information. This is true for something as innocuous as a general contact form. If that contact form is on a hospital or bank Web site, it may draw sensitive information from users - even if they are cautioned against providing it.


text:
A License to Print Money
Wendy Grossman reports on the release of the Draft Communications Data Bill and looks over some of the major comments and criticisms it has recevied.
Image: Houses of Parliament CC-BY-NC Flickr: racoles
"It's only a draft," Julian Huppert, the Liberal Democrat MP for Cambridge, said repeatedly. He was talking about the Draft Communications Data Bill (PDF), which was published on Wednesday. On the 14th, in a room in a Parliamentary turret, Hupper convened a meeting to discuss the draft; in attendance were a variety of Parliamentarians plus experts from civil society groups such as Privacy International, the Open Rights Group, Liberty, and Big Brother Watch. Do we want to be a nation of suspects?
The Home Office characterizes the provisions in the draft bill as vital powers to help catch criminals, save lives, and protect children. Everyone else - the Guardian, ZDNet UK, and dozens more - is calling them the "Snooper's charter".
Huppert's point is important. Like the Defamation Bill before it, publishing a draft means there will be a select committee with 12 members, discussion, comments, evidence taken, a report (by November 30, 2012), and then a rewritten bill. This draft will not be voted on in Parliament. We don't have to convince 650 MPs that the bill is wrong; it's a lot easier to talk to 12 people. This bill, as is, would never pass either House in any case, he suggested.
This is the optimistic view. The cynic might suggest that since it's been clear for something like ten years that the British security services (or perhaps their civil servants) have a recurring wet dream in which their mountain of data is the envy of other governments, they're just trying to see what they can get away with. The comprehensive provisions in the first draft set the bar, softening us up to give away far more than we would have in future versions. Psychologists call this anchoring, and while probably few outside the security services would regard the wholesale surveillance and monitoring of innocent people as normal, the crucial bit is where you set the initial bar for comparison for future drafts of the legislation. However invasive the next proposals are, it will be easy for us to lose the bearings we came in with and feel that we've successfully beaten back at least some of the intrusiveness.
But Huppert is keeping his eye on the ball: maybe we can not only get the worst stuff out of this bill, but make things actually better than they are now; it will amend RIPA. The Independent argues that private companies hold much more data on us overall, but that article misses that this bill intends to grant government access to all of it, at any time, without notice.
The big disappointment in all this, as William Heath said on Thursday, is that it marks a return to the old, bad, government IT ways of the past. We were just getting away from giant, failed public IT projects like the late unlamented NHS platform for IT and the even more unlamented ID card towards agile, cheap public projects run by smart guys who know what they're doing. And now we're going to spend £1.8 billion of public money over ten years (draft bill, p92) building something no one much wants and that probably won't work? The draft bill claims - on what authority is unclear - that the expenditure will bring in £5 to £6 billion in revenues. From what? Are they planning to sell the data?
Or are they imagining the economic growth implied by the activity that will be necessary to build, install, maintain, and update the black boxes that will be needed by every ISP in order to comply with the law. The security consultant Alec Muffet has laid out the parameters for this SpookBox 5000: certified, tested, tamperproof, made by, say, three trusted British companies. Hundreds of them, legally required, with ongoing maintenance contracts. "A license to print money," he calls them. Nice work if you can get it, of course.
So we're talking - again - about spending huge sums of government money on a project that only a handful of people want and whose objectives could be better achieved by less intrusive means. Give police better training in computer forensics, for example, so they can retrieve the evidence they need from the devices they find when executing a search warrant.
Ultimately, the real enemy is the lack of detail in the draft bill. Using the excuse that the communications environment is changing rapidly and continuously, the notes argue that flexibility is absolutely necessary for Clause 1, the one that grants the government all the actual surveillance power, and so it's been drafted to include pretty much everything, like those contracts that claim copyright in perpetuity in all forms of media that exist now or may hereinafter be invented throughout the universe. This is dangerous because in recent years the use of statutory instruments to bypass Parliamentary debate has skyrocketed. No. Make the defenders of this bill prove every contention; make them show the evidence that makes every extra bit of intrusion necessary.
Wendy M. Grossman's Web site has an extensive archive of her books, articles, and music, and an archive of all the earlier columns in this series.
By Wendy Grossman on Jun 18, 2012


text:
Royal Photo Taken By Single Mom Has Already Made Thousands in the U.K.
Viral Royal Photo Taken By Single Mom Already Raking In Thousands
The Christmas snapshot of the Royal Fab Four seen 'round the world -- taken by a single mother -- has already generated thousands of dollars ... and there's more to come.
TMZ has learned the photo taken by Karen Anvil -- a less-than-amateur photog -- has already raked in about 5,000 pounds in the U.K. from licensing. That's about $6,700 in USD.
We're told that money is just from one of eight territories the photo's being circulated in so far -- the figures for the other territories, which includes the U.S., haven't been fully calculated yet. However, we're told Karen is in for a "very happy New Year."
WE'RE GETTING THE ROYAL TREATMENT!
As for Karen ... she tells us she plans to use part of that dough to pay for her daughter's college tuition -- as well as to pay for a U.S. trip for the kid's 18th birthday.
Her story is fascinating. Karen took the photo of Meghan, Harry, Kate and William using her iPhone SE, and wasn't planning on charging for it 'til she learned she could pick up some extra bones.
Prince Harry Grills Barack Obama About Aretha, LeBron and Underwear
Meghan Markle Embraced by Royal Family on Christmas Day
Meghan Markle Prince Harry Kate Middleton Prince William Family Royal Family Viral Exclusive


text:
Q: Adaptative trim subroutine With this example, I would like to learn the best method to code an adaptative subroutine.
I need a subroutine that trim text (actually, it is a pretext, my subroutine could have done anything else).
In order to be more versatile, I would like my subroutine to accept different types of arguments:
my @input = (' A ', '  B', 'C  ');

*

*my @trimmed = trim(@input);

*trim(\@input);

*my $out = trim($input[0]); which returns 'A'

*trim(\$input[0]); which trim the first element of @input;

*trim(\@a, \@b, \@c); Each array of strings is trimmed

*my $out = trim(\@a, ' A ', '  B'); $out = (qw/A B/); (behavior to be discussed)
Here's my current ugly solution:
sub trim {
    state $re = qr/^\s+|\s+$/m;
    my @a;
    for(@_) {
        if(ref eq 'SCALAR') { $$_ =~ s/$re//g;    }
        elsif(ref)          { trim(\$_) for(@$_); }
        else                { push @a, s/$re//gr; }
    }
    return \@a if @a > 1;
    return $a[0] if $a[0];
}

Is there any better solution of this implementation that support different kind of input as I suggested above ?
The main reason of this question concerns my final application in which I am carrying text that can be stored in a string, an array of strings or even a hash.
I suppose it is better to write:
trim(\@allmytexts);
align(\@allmytexts, align=>'right');

Than:
for(@allmytexts) {
   trim($_);
   align($_, align=>'right');
}

A: Sounds way too complicated to me. The usage has gotta be easier to read and remember than that![1]. Just have trim take a scalar (defaulting to $_).
sub trim(_) { $_[0] =~ s/^\s+|\s+\z//rg }

All your cases can easily be handled by that, starting with
$x = trim($x);
@a = map trim, @a;

You can make in-place version too.
sub trim_i(_) { s/^\s+|\s+\z//g for $_[0] }

This would used as follows:
trim_i($x);
trim_i for @a;

The other possibility is to take a list of scalars (no default).
sub trim {
   wantarray
      ? map s/^\s+|\s+\z//rg, @_
      : $_[0] =~ s/^\s+|\s+\z//rg
}

$x = trim($x);
@a = trim(@a);

sub trim_i {
   s/^\s+|\s+\z//rg for @_;
}

trim_i($x);
trim_i(@a);

But it's a bit odd. Especially since my $x = trim($y, $z); is possible.

*

*Also, it uses type-based polymorphism, which is not a good idea in Perl. Your code behaves unexpectedly when faced with an object that overloads stringification.

A: This question is off topic, and will likely be closed soon.
However, "Is it correct to ask for this type of behavior in such subroutines ?"
I would say no. I am far from clear about what it is you want this subroutine to do with the information in front of me, and, without referring to your documentation, I would certainly be struggling to remember how to call it if I hadn't used it for a day or two. You will find that everybody uses it by writing
$string = trim($string)

because that is what they remember.
It also looks like you're not clear yourself what some calls do, hence
my $out = trim(\@a, ' A ', ' B'); $out = (qw/A B/); (behavior to be discussed)

I suspect that you are used to a language with a different passing mechanism, and something like this would be useful. In Perl, everything is passed by alias; so an operation on an element of the @_ array is equivalent to the same operation on the actual parameter. That means that a subroutine could modify any writeable value if you pass that value as a parameter.
With that in mind, passing a reference to indicate that it is to be modified in-place is nothing more than a flag that dictates how the subroutine is to behave, together with the encumbrance that the reference has to be dereferenced before it can be used.
Ask yourself how often you have seen a commonly-used library function behave like this. For instance, there are separate calls to index and rindex to do very similar things, and the existing core operator lc is reasonably similar to what trim is trying to do but it only ever takes one parameter and returns the transformed result. sprintf could be seen as a variant of printf, if only it knew that, if the file handle parameter was a reference to a scalar, it should put the string into the variable instead of writing it to a file handle. But it wasn't designed like that.
I can only offer an alternative solution to a defined problem. You don't explain the real-life difficulty, and since you're not sure yourself what your trim should do I doubt if anyone can help you to improve it.
Something else to ask yourself is, what should the return value be when a reference is passed and the value is modified in place? It may be obvious that it should return the value after it has been changed, but, since you're writing adaptive code, how about changing the return value depending on whether the call was in scalar, list, or void context? Or, even better, make trim an lvalue subroutine so that you can write something like
my $n = q{               999                     };
++trim($n);