text:
The working principle and classification of solar cells
How photovoltaic power to work.
Photovoltaic power generation is a technology that directly converts light energy into electrical energy by utilizing the photovoltaic effect of the semiconductor interface. The key component of this technology is the solar cell. The solar cells are packaged and protected in series to form a large-area solar cell module, and then combined with a power controller and the like to form a photovoltaic power generation device. The advantage of photovoltaic power generation is that it is less restricted by geographical area, because the sun shines on the earth; the photovoltaic system also has the advantages of safe and reliable, no noise, low pollution, no need to consume fuel and erecting transmission lines to generate electricity on site and short construction period.
Photovoltaic power generation uses solar cells to convert solar energy directly into electrical energy based on the principle of photovoltaic effect. Whether it is independent use or grid-connected power generation, photovoltaic power generation system is mainly composed of three parts: solar panels (components), controllers and inverters. They are mainly composed of electronic components and do not involve mechanical components. Therefore, photovoltaic power generation equipment Extremely refined, reliable, stable, long life, easy installation and maintenance. In theory, photovoltaic power generation technology can be used in any occasion where power is required, from spacecraft to household power supplies, to megawatt power stations, to toys, and photovoltaic power sources everywhere. The most basic components of solar photovoltaic power generation are solar cells (sheets), such as monocrystalline silicon, polycrystalline silicon, amorphous silicon and thin film batteries. At present, single crystal and polycrystalline batteries are used the most, and amorphous batteries are used for some small systems and calculator auxiliary power supplies.
The efficiency of domestic crystalline silicon cells is about 10 to 13%, and the efficiency of similar foreign products is about 18 to 23%. A solar panel composed of one or more solar cells is referred to as a photovoltaic module. At present, photovoltaic power generation products are mainly used in three aspects: First, to provide power for non-electrical occasions, mainly to provide electricity for the living production of residents in the vast areas without electricity, microwave relay power, communication power, etc. In addition, some mobile Power supply and backup power; Second, solar energy daily electronic products, such as various types of solar chargers, solar street lights and solar lawn lights; third, grid-connected power generation, which has been widely implemented in developed countries. China's grid-connected power generation has not yet started, but some of the electricity used in the 2008 Beijing Olympic Games will be provided by solar power and wind power.
Type of solar cell
(1) Monocrystalline silicon solar cells
The photoelectric conversion efficiency of monocrystalline silicon solar cells is about 15%, and the highest is 24%. This is the highest photoelectric conversion efficiency among all kinds of solar cells, but the production cost is so large that it cannot be widely used. Commonly used. Since monocrystalline silicon is generally encapsulated with tempered glass and waterproof resin, it is durable and has a service life of up to 15 years and up to 25 years.
(2) Polycrystalline silicon solar cells
The manufacturing process of polycrystalline silicon solar cells is similar to that of monocrystalline silicon solar cells, but the photoelectric conversion efficiency of polycrystalline silicon solar cells is much lower, and its photoelectric conversion efficiency is about 12% (July 1, 2004, Japan's Sharp listing efficiency is 14.8%. The world's most efficient polysilicon solar cell). In terms of production cost, it is cheaper than monocrystalline silicon solar cells, the material is simple to manufacture, saves power consumption, and the total production cost is low, so it has been greatly developed. In addition, the life of polycrystalline silicon solar cells is also shorter than that of monocrystalline silicon solar cells. In terms of performance and price ratio, monocrystalline silicon solar cells are slightly better.
(3) Amorphous silicon solar cells
Amorphous silicon solar cells are new thin film solar cells that appeared in 1976. They are completely different from single crystal silicon and polycrystalline silicon solar cells. The process is greatly simplified, the silicon material consumption is small, and the power consumption is lower. The advantage is that it can generate electricity in low light conditions. However, the main problem of amorphous silicon solar cells is that the photoelectric conversion efficiency is low. At present, the international advanced level is about 10%, and it is not stable enough. As time goes by, its conversion efficiency is attenuated.
(4) Multi-component solar cells
A multi-component solar cell refers to a solar cell that is not made of a single element semiconductor material. Nowadays, there are many varieties of research in various countries, most of which have not been industrialized, mainly including the following: a) cadmium sulfide solar cells b) gallium arsenide solar cells c) copper indium selenide solar cells (new multi-band gap gradient Cu (In, Ga) )Se2 thin film solar cell)
Cu(In, Ga)Se2 is a kind of solar absorbing material with excellent performance. It has a multi-layer semiconductor material with gradient energy band gap (the energy level difference between conduction band and valence band), which can expand the solar absorption spectrum range and improve photoelectric conversion. effectiveness. Based on this, a thin film solar cell with a significantly higher photoelectric conversion efficiency than a silicon thin film solar cell can be designed. The photoelectric conversion rate that can be achieved is 18%. Moreover, such thin film solar cells have not been found to have a performance degradation effect (SWE) due to optical radiation, and the photoelectric conversion efficiency thereof is improved by about 50~ compared with the currently commercial thin film solar panels. 75% is the world's highest level of photoelectric conversion efficiency in thin film solar cells.
←Previous: What is the cause of charging the electric car battery?
Next: Classification of electric bike chargers→


text:
SolarQuarterEmpowering. Insightful. Engaging.
Arabic Chinese (Simplified) English Filipino French Indonesian Malay Spanish Thai Vietnamese
SolarQuarterENGAGING. ENRICHING.
Bahrain's EWA And nogaholding Powers Beban With 100% Renewable Energy
President El-Sisi Meets The Chairman And CEO of India's ReNew Power; Discusses Cooperation
SEZAD Is Poised For The Greatest Contribution To Oman's Energy Sustainability Goals – Dr. Ali Masoud al Sunaidy
France And Iraq Signs Strategic Partnership Agreements
Week In Middle East: UAE Supports India's RE Ambitions To Achieve 450 GWs By 2030; Masdar To Develop 5 GW Of RE Projects; And...
Egypt And India Discusses Cooperation In Renewable Energy
HE Saeed Al Tayer Emphasises Dubai's Clear Strategy And Roadmap To Reach 100% Of Energy Production Capacity From Clean Energy Sources By 2050
Sungrow Signs Distribution Agreement In The Kingdom Of Saudi Arabia With Al-Babtain LeBlanc
Emerge Partners With Coca-Cola Al Ahlia Beverages' On New Solar Project
SolarQuarter Middle East Nov-Dec 2022 Issue
Magnom Properties And Forbes Announce Partnership To Build 'Forbes International Tower With Rooftop Solar' In Egypt
UAE Supports India's Renewable Energy Ambitions To Achieve 450 GWs By 2030
First Abu Dhabi Bank Invested AED25.7 Million On Sustainable Projects In 2022
AMANA Construct Delivers Mega Logistic Center For DB Schenker Powered With 100% Renewable Energy
ADNOC Distribution To Install Solar Panels To Power Service Stations
Home Insights ASEAN Yet To Unleash The Potential Of Solar And Wind Energy –...
ASEAN Yet To Unleash The Potential Of Solar And Wind Energy – Report
Pooja Chandak
Among 10 ASEAN (the Association of Southeast Asian Nations) member states, five countries dominate the region's total electricity generation (covering 89% generation). These major countries consist of Indonesia, Malaysia, the Philippines, Thailand and Viet Nam. The contribution of these major countries will be essential to achieving the electricity transition towards clean energy in the region.
Southeast Asia has emerged as possibly the most crucial region for future energy transition as the pace of transition picks up in China and India. The region offers enormous potential for renewable energy sources, especially solar and wind. However, they have yet to show significant progress in clean energy deployment.
As one of the world's fastest-growing regions in terms of economic growth and electricity demand, achieving its net zero emissions in the future will depend on the pace of renewables uptake. The progress of clean electricity generation in ASEAN's five major countries (Indonesia, Malaysia, the Philippines, Thailand and Viet Nam), henceforth "ASEAN 5", which makes up 89% of the region's total electricity generation, shows a positive trend in the past years. Nevertheless, clean electricity could not keep up with the fast-rising electricity demand. Therefore, as of 2021, the share of clean electricity remains low with the share of fossil fuel increased in the region compared to 2015.
Around three-quarters of the growth in global clean electricity generation in 2021 came from solar and wind. Most 1.5-degree aligned models suggest that going forward, solar and wind should account for a similar proportion of clean electricity. However, solar and wind-generated only 4% of ASEAN 5's electricity last year, lagging behind its peers like China (11%) and India (8%).
Also Read Sharp Ventures Solar Sdn Bhd Awards RM185.01 Million Solar Photovoltaic Project To SunCon
Analysis of current power sector development plans shows the total share of solar and wind in ASEAN 5 will rise from 4% of electricity in supply in 2021 to 11% by 2030. But even more, ambition is needed to put them on a 1.5-degree pathway.
ASEAN electricity demand grew 22% from 2015 to 2021, higher than the global average, which increased by 16%. From 2015 to 2021, clean power generation only met 39% of ASEAN's rise in electricity demand and 48% was met with fossil fuels. 39% of the rise in electricity demand in Viet Nam, 12% in the Philippines and 45% in Thailand were met by clean sources. Electricity generation from fossil fuels increased 21% in all five countries, matched by an increase in power sector CO2 emissions.
Solar and wind generated only 4% of the ASEAN's electricity last year, lagging behind peers like China (11%) and India (8%). Only Viet Nam (11%) exceeds the world average in solar and wind, which generated 10% of global electricity for the first time in 2021. The share of solar and wind in Thailand, the Philippines and Malaysia is 4.6%, 2.6% and 0.9% respectively.
Solar and wind only accounted for 0.2% of total electricity generation in Indonesia in 2020 (the latest data available).
Also Read MoP To Introduce Uniform Renewable Tariff For Central Pool Of Projects
Our analysis shows that by 2030, the latest energy plans would bring the share of solar and wind in this region up to 11% of the total electricity supply. Viet Nam is expected to generate 18% solar and wind in its total generation, the Philippines 16.5%, and Thailand 9.6%. Malaysia and Indonesia would reach 3.4% and 2% of solar and wind generation share respectively.
"Governments should unleash the power of solar and wind, as is happening already in China, India, and across much of the world. As fossil fuel prices soar through the roof, solar and wind prices remain low, providing affordable, homegrown energy. Solar and wind are progressing across Southeast Asia, but more aggressive targets and timely execution are needed to utilise the vast potential. Governments need to redress 2030 energy plans," said Achmed Shahram Edianto, Asia Electricity Analyst, Ember.
ASEAN countries have targets in place for accelerating clean energy deployment, individually (national energy plans) and regionally (through the ASEAN Plan of Action for Energy Cooperation). However, our report shows that in the ASEAN 5, clean energy planned under these targets could not keep up with rising demand. Despite clean energy generation constantly increasing in recent years, its share remains low. This trend is what has led to the current domination of coal share in the electricity mix.
While the world is shifting to solar and wind following cost declines, solar power is still at the margin of the region's generation mix, and wind power is almost invisible. Only Viet Nam surpassed the world average with 11% solar and wind generation in 2021. Other countries in the region have solar and wind shares below 5%, lagging behind their peers.
Also Read ACEN Set To Commence Construction Of 60 MW Pangasinan Solar
The vast potential of clean energy in the ASEAN 5 is unfortunately not reflected in its latest 2030 plans. Our analysis shows that by 2030, the current energy plans would bring the share of solar and wind in this region up to 11% of total generation. To be aligned with the IEA Net Zero pathway, solar and wind uptake should be accelerated rapidly. The current solar and wind deployment target would only be less than half of the IEA target. More ambitious solar and wind deployment plans are needed.
SouthEastAsia
Previous articleTurkey Makes New Provisions For Solar System Irrigation
Next articleThe GCC Governments Are Aggressively Promoting The Renewables Sector esp. Solar, Wind & Green Hydrogen: Nat Vora, CFO, Solarwadi
Pooja is a journalist and mass communication graduate who specializes in content creation. She is passionate about clean energy, including solar and electric vehicles.
MNRE Increases CFA for Residential Category in North Eastern and Hilly States/UT
Bhopal Municipal Corporation Seeks 90 Crore Loan to Set Up Solar, Wind Power Project in Neemuch
Rajasthan Govt Ties Up With Rays Power Infra To Build 1800 MW Solar Park
CEPSA Partners with EDP To Promote Andalusian Green Hydrogen Valley Project in Spain
Globeleq Completes Financial Restructuring of Soutpan PV Plant in South Africa
Roofsol Energy Receives Repeat Order for Rooftop Solar System from Sportking India
Kehua Tech Provides PCS Integrated Solution For The Largest BESS Project In Brazil
Kehua Tech Made Its Debut With PV+ESS Solutions In Intersolution Belgium 2023
GoldenPeaks To Supply Carbon Free Electricity To Mondelez in Poland
BrightNight Announces Differentiated 100 MW Solar-Wind Hybrid Power Project in India
JDC, COREnergy Launches First Solar-Powered Commercial Building In Cebu
FirstView Media Ventures Pvt Ltd
3:00 pm - 4:30 pm IST
String Inverter Installation and Commissioning Training for South Asia
12:00 pm SMT
Solar Market Outlook: South East Asia 2023
1:30 pm - 3:00 pm SAST
Top 5 Solar Developments in Southern Africa
SolarQuarter Business Meet – Kerala 2023
9:00 am - 5:00 pm IST
Net-Zero Energy Leadership Summit 2023 -New Delhi
MNRE Increases CFA for Residential Category in North Eastern and Hilly States/UT 31st January 2023
Bhopal Municipal Corporation Seeks 90 Crore Loan to Set Up Solar, Wind Power Project in Neemuch 31st January 2023
Rajasthan Govt Ties Up With Rays Power Infra To Build 1800 MW Solar Park 31st January 2023
CEPSA Partners with EDP To Promote Andalusian Green Hydrogen Valley Project in Spain 30th January 2023
Globeleq Completes Financial Restructuring of Soutpan PV Plant in South Africa 30th January 2023
© SolarQuarter - SolarQuarter is one of the world's largest global solar energy sector media with an annual reach to 1,000,000+ industry professionals. We bring to you the most exciting, insightful, and engaging content in the form of daily news updates, market research & insights, trend analysis, and, digital & in-person business events.
Contact us: info@firstviewgroup.com
EMobility+
WindInsider
EnergyStoragePro
© FirstView Media Ventures Pvt. Ltd. All rights reserved.
Email: info@firstviewgroup.com
MNRE Increases CFA for Residential Category in North Eastern and Hilly...
Bhopal Municipal Corporation Seeks 90 Crore Loan to Set Up Solar,...

redpajama_set_name: RedPajamaCommonCrawl


text:
#ifndef ADVERTAPP_H
#define ADVERTAPP_H
#include <string>
#include <vector>
#include "Advert.h"
#include "Newspaper.h"
#include "LoginScreen.h"
#include "AddAdvertScreen.h"
#include "MainMenu.h"
#include "MessageScreen.h"
#include "EditAdvertScreen.h"
#include "ReviewAdvertScreen.h"
#include "SelectionScreen.h"
#include "EditUserScreen.h"
#include "RegisterUserScreen.h"
#include "Database.h"
#include "Guest.h"
#include "AddUserScreen.h"
#include "ListScreen.h"
#include "AddNewspaperScreen.h"
#include "EditNewspaperScreen.h"
using namespace std;
class AdvertApp {

    User* currentUser;
    vector<User*>* users;
    vector<Newspaper*>* newspapers;
    vector<Advert*>* adverts;
    Database db;
    MainMenu mainMenu;
public:
    AdvertApp();
    const User* getCurrentUser() const;
    void addAdvert();
    void listAdvert();
    void listAllAdvert();
    void editAdvert();
    void deleteAdvert();
    void reviewAdvert();
    void addUser();
    void editUser();
    void deleteUser();
    void listNewspapers();
    void addNewspaper();
    void editNewspaper();
    void deleteNewspaper();
    void registerUser();
    void login();
    void start();
    void close();
    ~AdvertApp();
};

#endif

redpajama_set_name: RedPajamaGithub


Welcome to Herb Fancy's Eye Pillows Page.
Each of the Eye Pillows are handmade using a blend of flax, herbs, and crystals formulated for its specific use. Each are made in small batches to ensure freshness.
Gently place this eye pillow over your eyes to seal out the light. This eye pillow is excellent to help you breathe a bit easier, helps to clear the sinuses.
**Material color and print will vary upon availability.
Ingredients: Flax seed, peppermint, spearmint, eucalyptus, carnelian, jade, moss opal.
*Material color and print will vary upon availability.
Lavender is known for its relaxing properties and is used to ease tension, stress, headaches, and migraines. Place the eye pillow gently over your eyes allowing it to seal out the light.
This herbal blend aids relaxation, ease tension, nervousness, stress, headaches, migraines, promotes restful sleep. Place the eye pillow gently over your eyes allowing it to seal out the light.
Gently place this eye pillow over your eyes allowing it to seal out the light. This special blend helps those who have trouble falling asleep or going back to sleep.


FRESNO–The Armenian Students Organization and Armenian Studies Program of California State University–Fresno are co-sponsoring the 7th Armenian Film Festival from 7:00-10:00 PM on Friday–February 10–2006 in the Industrial Technology Building–Room 101–on the Fresno State campus.
The featured film for the Festival is My Son Shall Be Armenian–directed by Hagop Goudsouzian. Exploring the question of Armenian identity–My Son Shall Be Armenian–follows the first voyage of filmmaker Hagop Goudsouzian–and five fellow Montreal men and women of Armenian descent–to Armenia in search of survivors of the Armenian genocide.
Admission to the 7th Annual Armenian Film Festival is free and filmgoers will have the opportunity to discuss the films after the screening of each short film. The films–in English and Armenian–are all directed and produced by a new generation of Armenian filmmakers.
This program is supported–in part–by funds from the University Student Union Diversity Awareness Program.
The 7th Annual Film Festival is open to the public and admission is free. Parking restrictions in Lots K–L–and Q–will be relaxed after 6:30 PM. For more information about the 7th Annual Armenian Film Festival–call the Armenian Studies Program office at (559)278-2669.
Exploring the question of Armenian identity–My Son Shall Be Armenian follows the voyage of filmmaker Hagop Goudsouzian–who–accompanied by five Canadian men and women of Armenian origin–returned to the land of his ancestors in search of survivors of the genocide of 1915.
The little band combed the Armenian countryside looking for survivors. The film is full of emotionally arresting desert photographs–in which the bones of mass graves are still visible–evoking the horror that took place there. The images in the film are accompanied by a stirring narration written by Michel Langlois and read by Goudsouzian.
Through the moving testimony of those surviving centenarians and the funny–touching accounts of his fellow travelers from the New World–Hagop Goudsouzian has crafted a dignified and poignant film on the need to make peace with the past in order to turn toward the future. The film is in French with English subtitles.
Born in Egypt–Hagop Goudsouzian is of Armenian descent and currently lives in Toronto. He has a wealth of experience in film and video production. As well as being a producer and director–Hagop Goudsouzian is also a photographer–whose work was exhibited at the Bibliotheque Nationale du Quebec as well as in various North American galleries.


text:
Bogdan Zakrzewski (25 September 1916 in Poznań – 23 October 2011 in Wrocław) was a Polish historian and researcher of Polish literature. He was a professor of the University of Wrocław (since 1958), editor-in-chief of Pamiętnik Literacki (1960–1998), member of the Polish Academy of Learning (since 1992).

Zakrzewski was a researcher of Polish literature of Romanticism, patriotic and revolutionary songs of 19th century, literature and folklore of Silesia.

Notable works
 Mickiewicz w Wielkopolsce (1949)
 Tematy śląskie (1973)
 Fredro i Fredrusie (1974)
 Fredro z paradyzu (1976)
 Palen na cara (1979)
 Sztandar i krew (1982)
 Hajże na Soplicę (1990)
 Fredro nie tylko komediopisarz (1993)
 Dwaj wieszcze, Mickiewicz i Wernyhora (1996)
 "Natust est" Pan Tadeusz (2001)

References

Further references

 Zmarł badacz romantyzmu prof. Bogdan Zakrzewski

1916 births
2011 deaths
Polish literary historians
Writers from Poznań
20th-century Polish historians
Polish male non-fiction writers
Academic staff of the University of Wrocław

redpajama_set_name: RedPajamaWikipedia


text:
prime motor group used cars
Look up prime motor group used cars in Wiktionary, the free dictionary.
prime motor group used carsPart of the reason for the surge in enquiries is that Euroglaze's website currently ranks on page 1 of Google searches for REHAU frames. This is attributed to the fact that the company's web partner has updated the website's architecture, switched the security protocols and kept pace with Google's changing algorithms on SEO. Martin Nettleton adds: "We invested in the campaign to target those larger installation and distribution companies increasingly dissatisfied with the big fabricators who are starting to compete with them by setting up their own networks of trade counters and distribution outlets. "Our entry for this award is a thank you to them for their vision and willingness to do things differently. It's also a thank you to BEIS for the courage and far-sightedness they have shown in working constructively with industry to fit their approach to the needs and circumstances of UK manufacturing." Ideally suited for a wide range of applications, the PURe® aluminium windows are available as tilt and turn or casement windows. Senior's innovative door range also features a choice of the PURe® FOLD and PURe® SLIDE options. The Barnsley based REHAU fabricator has seen a surge in enquiries from installers and consumers in response to its ongoing advertising, PR and web campaign and these are being passed to its stockists and distributors nationwide. The programme will seek to provide applicable and commercially relevant insight – and British Glass wants to hear from potential presenters who have successfully implemented energy and carbon reduction projects in large-scale manufacturing (in any relevant sector) by securing funds from:
1 classic motor car company
2 preston motors used cars
3 sun motor cars inc
4 how to build a motor car
This motor trader uk cars for sale page lists articles associated with the title Seo.
If an james motor cars led you here, you may wish to change the link to point directly to the intended article.
general motors concept cars
car ac motor


text:
HomeMultiplayerFall Guys : Ultimate Knockout
Fall Guys : Ultimate Knockout
pria manja August 10, 2020
Fall Guys is a massively multiplayer party game with up to 60 players online in a free-for-all struggle through round after round of escalating chaos until one victor remains!
If you are looking for a good video game for the Xbox, PlayStation or PC, you should check out Fall Guys Ultimate knockout. This is a first person shooter game where you must survive the zombie-like game and complete missions in order to advance through the levels and earn extra points. It was created by Mediatic and published by Devolver digital.
The game is similar to the Call of Duty games where you use an assault rifle in order to kill zombies and enemies. In Fall guys Ultimate knockout, you use an automatic pistol as well. You will have to use the pistol in order to stop the zombies from getting to you. The goal of this game is to survive all the levels by killing the zombies and using the pistols and rifles that you have. However, you will not have an unlimited supply of ammunition as the game is single player only.
The game has three different levels in which you can choose from. The first level is called "Nemesis". This is a level that is made up of many zombies that will try to attack you. You will need to use your guns in order to take out the zombies as fast as possible. The level after being known as "Virus".
The third level is called "Dead Zone". Here you will need to complete a mission that requires you to kill all the zombies and use special weapons to destroy the zombies that are hiding in walls. After you complete the mission, you will earn a point and the game will end.
There are many things that you can do while playing this game. You can explore the different areas of the game and try to unlock achievements in order to get points. However, this game is mainly for the fans who like the survival mode type of games.
If you want a more challenging experience, you can choose to play in the "No holds barred" version of the game in Fall guys Ultimate knockout. Here, you can play in a fully automated mode without having to worry about dying because you don't have to fight the zombies all the time.
To find a game to play, you can search for the game online or you can look for the reviews on Xbox Live or PlayStation Network in order to get the best version of this game to play. In fact, the best thing to do is to play the demo before buying it so that you can see if it is for you. and the people who have played it can give their opinion. You can also find reviews on the official website of the game to learn more information about the game.
In short, if you want an addictive and fun video game for the Xbox, PlayStation or PC, you should try Fall guys Ultimate knockout. because it has great graphics, great music, great gameplay, and also a good storyline that keeps you hooked to the game for hours. Check out the review site below and try out this great game.
Although it has become very popular in the past few years, it is still a game that is played in many places around the world. This is because there is something about it that appeals to a lot of people.
Another great thing about Fall guys Ultimate knockout is that it can be played by all ages and not just teenagers. If you are a child or a teenager, you can easily play this game because it has all the features that you can think of.
Another great thing about this game is that the storyline of it is so realistic. since it is based in the future, it means that you will be able to see what is happening in the future.
Finally, you should check out the game to find out what other people think about it. so you can make the right decision when it comes to buying the game.
TITLE: Fall Guys: Ultimate Knockout
GENRE: Action, Casual, Indie, Massively Multiplayer, Sports
DEVELOPER: Mediatonic
PUBLISHER: Devolver Digital
RELEASE DATE: 4 Aug, 2020
GOOGLE DRIVE :
OS: Windows 10 64bit only
Graphics: NVIDIA GTX 660 or AMD Radeon HD 7950
Additional Notes: Gamepad Recommended
• Requires a 64-bit processor and operating system
• OS: Windows 7/8.1/10 (64-bit Required)
• Processor: Intel Core i7-4771 3.5 GHz / AMD FX-9370 4.4 GHz
• Memory: 8 GB RAM
• Graphics: NVIDIA GeForce GTX 970 (4 GB VRAM) / AMD Radeon RX 470 (4 GB VRAM)
• DirectX: Version 11
• Network: Broadband Internet connection
• Storage: 5 GB available space
2020 Casual Indie Multiplayer


SonoSite, the Bothell, WA-based maker of portable ultrasound machines, said today in its first-quarter financial report that its annual revenue for 2009 may be flat to down 10 percent compared with the previous year. The company (NASDAQ: SONO) said it is responding by cutting expenses 5 to 10 percent, a deeper round of cuts than the previous range it announced, of as much as 5 percent. It blamed dropping demand at U.S. hospitals, and less favorable foreign currency exchange rates.


Designed with pinstripes in a cropped silhouette, these pants by Eileen Fisher are ideal for styling with pumps and a sleek blazer.
Elevate your everyday look with this soft, sleek pair! Crafted from luxe knit materials and punctuated by a figure-skimming silhouette, these eye-catching pants are finished with an elastic yoke for an extra fitted touch.
These comfortable pants by Grace Elements feature a pull-on fit with bow details at the ankles for added feminine style.
You'll find the ultimate pairing of comfort and style with Belk's BCBG pants collection. This assortment of designer pants will immediately become your go-to style. BCBG pants are versatile enough for any venue. Dress up your soft, comfortable BCBG pants with a cute sweater or throw a BCBG dress over your leggings for effortless style. We carry a range of classic colors like blue, grey, and black so you can mix and match with bright BCBG tops for a look that really stands out. Want even more trendy options to add to your closet? Shop all BCBG clothing from belk.com today!


text:
Barry Manilow - 2:00 AM Paradise Cafe LP
Barry Manilow's tenth album. Released in 1984. A jazz themed album with a relaxing coating of lounge. Notable songs include...
Mavis Hee / 許美靜 - 都是夜歸人 LP
Mavis Hee's third album Living By Night. Originally released in 1996 on CD form only is now available on vinyl...
Akiko Yano / 矢野顕子 - Soft Landing LP
Akiko Yano's 2017 solo piano and vocal album. Featuring the 2019 vinyl release, available for purchase at our web store...
Sheena Easton - Take My Time LP
Sheena Easton's debut album. Released in 1981. Notable songs include "9 to 5", "Modern Girl", "One Man Woman" and more....
Tarcy Su Hui Lun / 蘇慧倫 - 戀戀真言 LP
Tarcy Su's 13th mandarin album. Originally released in 2001 on CD form only. Featuring the 2020 vinyl record release. A...
Tatsuro Yamashita / 山下達郎 - Ride On Time LP
Tatsuro Yamashita's fifth album. Released in 1980. Notable song include the album titled "Ride On Time", a timeless City Pop...
Art Garfunkel - Scissors Cut LP
Art Garfunkel's debut album. Released in 1981. Notable songs include "A Heart in New York", "Scissors Cut", "Hang On In"...
Yumi Matsutoya / 松任谷由実 - Delight Slight Light Kiss LP
Yumi Matsutoya's 20th album. Released in 1988. Notable track include the album opening song "リフレインが叫んでる (A Refrain is Crying Out)"....


text:
#include "IndexerFrontendAction.h"

#include <memory>
#include <string>
#include <utility>

#include "KytheGraphObserver.h"
#include "KytheVFS.h"
#include "absl/strings/str_cat.h"
#include "absl/strings/str_format.h"
#include "absl/strings/str_join.h"
#include "clang/Basic/Diagnostic.h"
#include "clang/Basic/SourceLocation.h"
#include "clang/Frontend/FrontendAction.h"
#include "clang/Tooling/Tooling.h"
#include "kythe/cxx/common/indexing/KytheGraphRecorder.h"
#include "kythe/cxx/common/json_proto.h"
#include "kythe/cxx/indexer/cxx/KytheClaimClient.h"
#include "kythe/cxx/indexer/cxx/KytheVFS.h"
#include "kythe/cxx/indexer/cxx/proto_conversions.h"
#include "kythe/proto/analysis.pb.h"
#include "kythe/proto/buildinfo.pb.h"
#include "kythe/proto/cxx.pb.h"
#include "kythe/proto/filecontext.pb.h"
#include "llvm/ADT/SmallString.h"
#include "llvm/ADT/Twine.h"
#include "third_party/llvm/src/clang_builtin_headers.h"

namespace kythe {

bool RunToolOnCode(std::unique_ptr<clang::FrontendAction> tool_action,
                   llvm::Twine code, const std::string& filename) {
  if (tool_action == nullptr) return false;
  return clang::tooling::runToolOnCode(std::move(tool_action), code, filename);
}

namespace {

// Message type URI for the build details message.
constexpr absl::string_view kBuildDetailsURI =
    "kythe.io/proto/kythe.proto.BuildDetails";

/// \brief Range wrapper around unpacked ContextDependentVersion rows.
class FileContextRows {
 public:
  using iterator = decltype(
      std::declval<kythe::proto::ContextDependentVersion>().row().begin());

  explicit FileContextRows(
      const kythe::proto::CompilationUnit::FileInput& file_input) {
    for (const google::protobuf::Any& detail : file_input.details()) {
      if (detail.UnpackTo(&context_)) break;
    }
  }

  iterator begin() const { return context_.row().begin(); }
  iterator end() const { return context_.row().end(); }
  bool empty() const { return context_.row().empty(); }

 private:
  kythe::proto::ContextDependentVersion context_;
};

bool DecodeDetails(const proto::CompilationUnit& Unit,
                   proto::CxxCompilationUnitDetails& Details) {
  for (const auto& Any : Unit.details()) {
    if (Any.type_url() == kCxxCompilationUnitDetailsURI) {
      if (UnpackAny(Any, &Details)) {
        return true;
      }
    }
  }
  return false;
}

std::string ExtractBuildConfig(const proto::CompilationUnit& Unit) {
  proto::BuildDetails details;
  for (const auto& Any : Unit.details()) {
    if (Any.type_url() == kBuildDetailsURI) {
      if (UnpackAny(Any, &details)) {
        return details.build_config();
      }
    }
  }
  return "";
}

bool DecodeHeaderSearchInfo(const proto::CxxCompilationUnitDetails& Details,
                            HeaderSearchInfo& Info) {
  if (!Details.has_header_search_info()) {
    return false;
  }
  if (!Info.CopyFrom(Details)) {
    absl::FPrintF(
        stderr,
        "Warning: unit has header search info, but it is ill-formed.\n");
    return false;
  }
  return true;
}

std::string ConfigureSystemHeaders(const proto::CompilationUnit& Unit,
                                   std::vector<proto::FileData>& Files) {
  std::vector<proto::FileData> OldFiles;
  OldFiles.swap(Files);
  const std::string HeaderPath = "/kythe_builtins/include/";
  std::unordered_set<std::string> NewHeaders;
  for (const auto* Header = builtin_headers_create(); Header->name != nullptr;
       ++Header) {
    auto Path = HeaderPath + Header->name;
    auto Data = Header->data;
    proto::FileData NewFile;
    NewFile.mutable_info()->set_path(Path);
    NewFile.mutable_info()->set_digest("");
    *NewFile.mutable_content() = Data;
    Files.push_back(NewFile);
    NewHeaders.insert(Path);
  }
  for (const auto& File : OldFiles) {
    if (NewHeaders.find(File.info().path()) == NewHeaders.end()) {
      Files.push_back(File);
    }
  }
  return "-resource-dir=/kythe_builtins";
}

std::string FormatLocation(clang::FullSourceLoc loc) {
  if (!loc.isValid()) {
    return "";
  }
  return absl::StrCat(loc.printToString(loc.getManager()), ": ");
}

// Collects text-formatted errors for later.
class TextErrorBuffer : public clang::DiagnosticConsumer {
 public:
  void HandleDiagnostic(clang::DiagnosticsEngine::Level level,
                        const clang::Diagnostic& info) override {
    DiagnosticConsumer::HandleDiagnostic(level, info);

    llvm::SmallString<100> buf;
    info.FormatDiagnostic(buf);
    switch (level) {
      case clang::DiagnosticsEngine::Error:
      case clang::DiagnosticsEngine::Fatal:
        errors_.push_back(
            absl::StrCat(FormatLocation(clang::FullSourceLoc(
                             info.getLocation(), info.getSourceManager())),
                         buf.c_str()));
        break;
      default:
        break;
    }
  }

  const std::vector<std::string>& errors() const { return errors_; }

 private:
  std::vector<std::string> errors_;
};
}  // anonymous namespace

std::string IndexCompilationUnit(
    const proto::CompilationUnit& Unit, std::vector<proto::FileData>& Files,
    KytheClaimClient& Client, HashCache* Cache, KytheCachingOutput& Output,
    IndexerOptions& Options ABSL_ATTRIBUTE_LIFETIME_BOUND,
    const MetadataSupports* MetaSupports,
    const LibrarySupports* LibrarySupports) {
  llvm::sys::path::Style Style =
      kythe::IndexVFS::DetectStyleFromAbsoluteWorkingDirectory(
          Unit.working_directory())
          .value_or(llvm::sys::path::Style::posix);
  HeaderSearchInfo HSI;
  proto::CxxCompilationUnitDetails Details;
  bool HSIValid = false;
  std::vector<llvm::StringRef> Dirs;
  if (DecodeDetails(Unit, Details)) {
    HSIValid = DecodeHeaderSearchInfo(Details, HSI);
    for (const auto& stat_path : Details.stat_path()) {
      Dirs.push_back(ToStringRef(stat_path.path()));
    }
  }
  std::string FixupArgument = ConfigureSystemHeaders(Unit, Files);
  if (HSIValid) {
    FixupArgument.clear();
  }
  clang::FileSystemOptions FSO;
  FSO.WorkingDir = Options.EffectiveWorkingDirectory;
  if (Style == llvm::sys::path::Style::windows) {
    FSO.WorkingDir = absl::StrCat("/", FSO.WorkingDir);
  }
  for (auto& Path : HSI.paths) {
    Dirs.push_back(ToStringRef(Path.path));
  }
  llvm::IntrusiveRefCntPtr<IndexVFS> VFS(
      new IndexVFS(Options.EffectiveWorkingDirectory, Files, Dirs, Style));
  KytheGraphRecorder Recorder(&Output);
  KytheGraphObserverOptions options;
  options.build_config = ExtractBuildConfig(Unit);
  options.default_corpus =
      Options.UseCompilationCorpusAsDefault ? Unit.v_name().corpus() : "";
  options.hash_recorder = Options.HashRecorder;
  KytheGraphObserver Observer(&Recorder, &Client, MetaSupports, VFS,
                              Options.ReportProfileEvent, options);
  if (Cache != nullptr) {
    Output.UseHashCache(Cache);
    Observer.StopDeferringNodes();
  }
  if (Options.DropInstantiationIndependentData) {
    Observer.DropRedundantWraiths();
  }
  Observer.set_claimant(Unit.v_name());
  Observer.set_starting_context(Unit.entry_context());
  for (const auto& Input : Unit.required_input()) {
    if (Input.has_info() && !Input.info().path().empty() &&
        Input.has_v_name()) {
      VFS->SetVName(Input.info().path(), Input.v_name());
    }
    const std::string& FilePath = Input.info().path();
    for (const auto& Row : FileContextRows(Input)) {
      if (Row.always_process()) {
        auto ClaimableVname = Input.v_name();
        ClaimableVname.set_signature(Row.source_context() +
                                     ClaimableVname.signature());
        Client.AssignClaim(ClaimableVname, Unit.v_name());
      }
      for (const auto& Col : Row.column()) {
        Observer.AddContextInformation(FilePath, Row.source_context(),
                                       Col.offset(), Col.linked_context());
      }
    }
  }
  if (MetaSupports != nullptr) {
    MetaSupports->UseVNameLookup(
        [VFS](const std::string& path, proto::VName* out) {
          return VFS->get_vname(path, out);
        });
  }
  std::unique_ptr<IndexerFrontendAction> Action =
      std::make_unique<IndexerFrontendAction>(
          &Observer, HSIValid ? &HSI : nullptr, LibrarySupports, Options);
  llvm::IntrusiveRefCntPtr<clang::FileManager> FileManager(
      new clang::FileManager(FSO, Options.AllowFSAccess ? nullptr : VFS));
  std::vector<std::string> Args(Unit.argument().begin(), Unit.argument().end());
  Args.insert(Args.begin() + 1, {"-nocudalib", "-w", "-fsyntax-only"});
  if (!FixupArgument.empty()) {
    Args.insert(Args.begin() + 1, FixupArgument);
  }

  // StdinAdjustSingleFrontendActionFactory takes ownership of its action.
  std::unique_ptr<StdinAdjustSingleFrontendActionFactory> Tool =
      std::make_unique<StdinAdjustSingleFrontendActionFactory>(
          std::move(Action));
  // ToolInvocation doesn't take ownership of ToolActions.
  clang::tooling::ToolInvocation Invocation(
      Args, Tool.get(), FileManager.get(),
      std::make_shared<clang::PCHContainerOperations>());

  TextErrorBuffer Diags;
  Invocation.setDiagnosticConsumer(&Diags);

  ProfileBlock block(Observer.getProfilingCallback(), "run_invocation");
  if (!Invocation.run()) {
    return absl::StrCat("Errors during indexing:",
                        absl::StrJoin(Diags.errors(), "\n"));
  }
  return "";
}

}  // namespace kythe


text:
Matthias Gromeier
Protein Synthesis Regulation
Growth & Proliferation Control in Cancer
Oncolytic Viruses
Viral Neuropathogenesis
Immunization Vectors
Professor of Neurosurgery, Neurosurgery, Neuro-Oncology, Neurosurgery 2016
Professor in Medicine, Medicine, Infectious Diseases, Medicine 2016
Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2016
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1999
Box 3020 Med Ctr, Durham, NC 27710
Research Drive, Rm 401D Msrb1, Durham, NC 27710
grome001@mc.duke.edu (919) 668-6205
Oncolytic Immunotherapy Laboratory
Postdoctoral Associate, Molecular Genetics & Microbiology, State University of New York at Stony Brook 1996 - 1999
Postdoctoral fellow, Molecular Genetics & Microbiology, State University of New York at Stony Brook 1993 - 1996
M.D., University of Hamburg (Germany) 1992
Associate Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2009 - 2016
Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2009 - 2016
Associate Professor of Neurosurgery, Neurosurgery, Neurosurgery 2010 - 2016
Associate Professor of Surgery, Neurosurgery, Neurosurgery 2009 - 2010
Assistant Professor in Medicine, Medicine, Infectious Diseases, Medicine 2002 - 2009
Assistant Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2002 - 2009
Assistant Professor of Surgery, Neurosurgery, Neuro-Oncology, Neurosurgery 2006 - 2009
Assistant Professor of Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 1999 - 2002
SEP 20, 2017 Duke Health News
Poliovirus Therapy Induces Immune Responses Against Cancer
MAY 17, 2016 The Daily Mail
Could polio help cure cancer? Therapy harnessing the virus 'destroys brain tumors'
Poliovirus Therapy Wins 'Breakthrough' Status
MAY 13, 2016 "CBS Evening News"
Promising brain cancer trial given breakthrough status by FDA
MAR 18, 2016 Washington Examiner
Dr. Matthias Gromeier: The right time to invest in cancer research
Vice President Visits to Discuss Cancer 'Moonshot'
APR 1, 2015 WRAL
Patients clamor for Duke cancer trial after '60 Minutes' report
MAR 31, 2015 Forbes
Commentary: What '60 Minutes' got right and wrong on Duke's polio virus trial against glioblastoma
MAR 31, 2015 Duke Research Blog
When Bad Viruses Do Good
APR 30, 2014 USA Today
Poliovirus injected into brain kills student's cancer
AUG 21, 2013 Al Jazeera America
An unlikely cancer cure?
Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2024
Innate Antiviral Signals for Cancer Immunotherapy awarded by National Institutes of Health 2018 - 2023
Oncolytic Polovirus, Immunotoxin, and Checkpoint Inhibitor Therapy of Gliomas awarded by National Institutes of Health 2015 - 2022
Is Low Tumor Mutational Burden Predictive of Response to Oncolytic Polio Virus Therapy in Recurrent Glioblastoma? awarded by National Institutes of Health 2019 - 2021
Translational Research in Surgical Oncology awarded by National Institutes of Health 2002 - 2021
The Role of CD155 in Leptomeningeal Dissemination and Oncolytic Virus Susceptibility in the Medulloblastoma Microenvironment awarded by Department of Defense 2018 - 2021
Regional Oncolytic Poliovirus Immunotherapy for Breast Cancer awarded by Department of Defense 2016 - 2021
Phase-1 clinical trial of PVSRIPO oncolytic immunotherapy in pediatric HGG 2016 - 2021
Establishing a Rationale for PVSRIPO Immunotherapy in Newly Diagnosed GBM 2019 - 2021
Poliovirus-Instigated APC Responses Against BRaf(V600E) for Pediatric Brain Tumor Immunotherapy awarded by V Foundation for Cancer Research 2018 - 2021
Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
Cancer Immunotherapy Through Intratumoral Activation of Recall Responses 2017 - 2019
Oncolytic Immunotherapy of Glioblastoma with Recombinant Poliovirus 2015 - 2019
Combining PVSRIPO Immunotherapy with Lomustine for the Treatment of Recurrent GBM 2017 - 2019
Recombinant Attenuated Poliovirus Immunization Vectors Targeting H3.3(K27M) in DIPG 2018 - 2019
Targeting Translation Control in Malignant Glioma awarded by National Institutes of Health 2007 - 2018
Oncolytic PVSRIPO Expressing Tumor Antigens as a Cancer Vaccine 2016 - 2017
Research Training In Neuro-Oncology awarded by National Institutes of Health 1998 - 2016
Phase II/III Manufacture of the Oncolytic Poliovirus Chimera, PVSRIPO 2015 - 2016
Cancer Biology Training Grant awarded by National Cancer Institute 1993 - 2016
Oncolytic Poliovirus Immunotherapy of Malignant Glioma 2014 - 2015
Oncolytic Virotherapy of Meningeal Cancer awarded by National Institutes of Health 2009 - 2015
Instrumentation for Quantitative Phosphoproteomics and Acetylomics awarded by National Institutes of Health 2014 - 2015
Oncolytic poliovirus therapy of malignant glioma 2014 - 2015
Enterovirus Vectors with Respiratory Tropism for Cancer Immunotherapy awarded by National Institutes of Health 2009 - 2012
Transgenic Mouse Model for the Common Cold awarded by National Institutes of Health 2008 - 2010
Cis and Trans-acting Factors in HCV Gene Expression awarded by National Institutes of Health 2005 - 2008
Cell Type-Specific Viral Translation in the CNS awarded by National Institutes of Health 2002 - 2007
Molecular Targeting of Breast Cancer 2004 - 2005
Genetically stable Picornavirus HIV Immunization vectors awarded by National Institutes of Health 2003 - 2005
Production of non-pathogenic oncolytic poliovirus chimeras for the treatment of brain tumors (Project #417) awarded by National Institutes of Health 2001 - 2002
Production of non-pathogenic oncolytic poliovirus chimeras for the treatment of brain tumors awarded by National Institutes of Health 2000 - 2001
Industry Relationships
Istari Oncology, Inc.
Chandramohan, Vidyalakshmi, Xuhui Bao, Xin Yu, Scott Parker, Charlotte McDowall, Yen-Rei Yu, Patrick Healy, et al. "Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations.." J Immunother Cancer 7, no. 1 (May 29, 2019). https://doi.org/10.1186/s40425-019-0614-0.
Yu, Xin, Mikhail Dobrikov, Stephen T. Keir, Matthias Gromeier, Ira H. Pastan, Ralph Reisfeld, Darell D. Bigner, and Vidyalakshmi Chandramohan. "Synergistic antitumor effects of 9.2.27-PE38KDEL and ABT-737 in primary and metastatic brain tumors.." Plos One 14, no. 1 (2019). https://doi.org/10.1371/journal.pone.0210608.
Dobrikov, Mikhail I., Elena Y. Dobrikova, and Matthias Gromeier. "Ribosomal RACK1:Protein Kinase C βII Modulates Intramolecular Interactions between Unstructured Regions of Eukaryotic Initiation Factor 4G (eIF4G) That Control eIF4E and eIF3 Binding.." Mol Cell Biol 38, no. 19 (October 1, 2018). https://doi.org/10.1128/MCB.00306-18.
Dobrikov, Mikhail I., Elena Y. Dobrikova, and Matthias Gromeier. "Ribosomal RACK1:Protein Kinase C βII Phosphorylates Eukaryotic Initiation Factor 4G1 at S1093 To Modulate Cap-Dependent and -Independent Translation Initiation.." Mol Cell Biol 38, no. 19 (October 1, 2018). https://doi.org/10.1128/MCB.00304-18.
Walton, Ross W., Michael C. Brown, Matthew T. Sacco, and Matthias Gromeier. "Engineered Oncolytic Poliovirus PVSRIPO Subverts MDA5-Dependent Innate Immune Responses in Cancer Cells.." J Virol 92, no. 19 (October 1, 2018). https://doi.org/10.1128/JVI.00879-18.
Thompson, Eric M., Michael Brown, Elena Dobrikova, Vijay Ramaswamy, Michael D. Taylor, Roger McLendon, Jennifer Sanks, Vidya Chandramohan, Darell Bigner, and Matthias Gromeier. "Poliovirus Receptor (CD155) Expression in Pediatric Brain Tumors Mediates Oncolysis of Medulloblastoma and Pleomorphic Xanthoastrocytoma.." J Neuropathol Exp Neurol 77, no. 8 (August 1, 2018): 696–702. https://doi.org/10.1093/jnen/nly045.
Desjardins, Annick, Matthias Gromeier, James E. Herndon, Nike Beaubier, Dani P. Bolognesi, Allan H. Friedman, Henry S. Friedman, et al. "Recurrent Glioblastoma Treated with Recombinant Poliovirus.." N Engl J Med 379, no. 2 (July 12, 2018): 150–61. https://doi.org/10.1056/NEJMoa1716435.
Bryant, Jeffrey D., Michael C. Brown, Mikhail I. Dobrikov, Elena Y. Dobrikova, Sarah L. Gemberling, Qing Zhang, and Matthias Gromeier. "Regulation of Hypoxia-Inducible Factor 1α during Hypoxia by DAP5-Induced Translation of PHD2.." Mol Cell Biol 38, no. 11 (June 1, 2018). https://doi.org/10.1128/MCB.00647-17.
Evans, Myron K., Michael C. Brown, Joseph Geradts, Xuhui Bao, Timothy J. Robinson, Mohit Kumar Jolly, Peter B. Vermeulen, et al. "XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype.." Cancer Res 78, no. 7 (April 1, 2018): 1726–38. https://doi.org/10.1158/0008-5472.CAN-17-1667.
Gromeier, Matthias, and Smita K. Nair. "Recombinant Poliovirus for Cancer Immunotherapy.." Annu Rev Med 69 (January 29, 2018): 289–99. https://doi.org/10.1146/annurev-med-050715-104655.
Chandramohan, Vidyalakshmi, Jeffrey D. Bryant, Hailan Piao, Stephen T. Keir, Eric S. Lipp, Michaela Lefaivre, Kathryn Perkinson, Darell D. Bigner, Matthias Gromeier, and Roger E. McLendon. "Validation of an Immunohistochemistry Assay for Detection of CD155, the Poliovirus Receptor, in Malignant Gliomas.." Arch Pathol Lab Med 141, no. 12 (December 2017): 1697–1704. https://doi.org/10.5858/arpa.2016-0580-OA.
Brown, Michael C., Eda K. Holl, David Boczkowski, Elena Dobrikova, Mubeen Mosaheb, Vidya Chandramohan, Darell D. Bigner, Matthias Gromeier, and Smita K. Nair. "Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs.." Sci Transl Med 9, no. 408 (September 20, 2017). https://doi.org/10.1126/scitranslmed.aan4220.
Brown, Michael C., and Matthias Gromeier. "MNK Controls mTORC1:Substrate Association through Regulation of TELO2 Binding with mTORC1.." Cell Rep 18, no. 6 (February 7, 2017): 1444–57. https://doi.org/10.1016/j.celrep.2017.01.023.
Brown, Michael C., and Matthias Gromeier. "MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling.." Mol Cell Oncol 4, no. 3 (2017). https://doi.org/10.1080/23723556.2017.1306010.
Holl, Eda K., Michael C. Brown, David Boczkowski, Megan A. McNamara, Daniel J. George, Darell D. Bigner, Matthias Gromeier, and Smita K. Nair. "Recombinant oncolytic poliovirus, PVSRIPO, has potent cytotoxic and innate inflammatory effects, mediating therapy in human breast and prostate cancer xenograft models.." Oncotarget 7, no. 48 (November 29, 2016): 79828–41. https://doi.org/10.18632/oncotarget.12975.
Brown, Michael C., and Matthias Gromeier. "Cytotoxic and immunogenic mechanisms of recombinant oncolytic poliovirus.." Curr Opin Virol 13 (August 2015): 81–85. https://doi.org/10.1016/j.coviro.2015.05.007.
Brown, Michael C., and Matthias Gromeier. "Oncolytic immunotherapy through tumor-specific translation and cytotoxicity of poliovirus.." Discov Med 19, no. 106 (May 2015): 359–65.
Brown, Michael C., Elena Y. Dobrikova, Mikhail I. Dobrikov, Ross W. Walton, Sarah L. Gemberling, Smita K. Nair, Annick Desjardins, et al. "Oncolytic polio virotherapy of cancer.." Cancer 120, no. 21 (November 1, 2014): 3277–86. https://doi.org/10.1002/cncr.28862.
Brown, Michael C., Jeffrey D. Bryant, Elena Y. Dobrikova, Mayya Shveygert, Shelton S. Bradrick, Vidyalakshmi Chandramohan, Darell D. Bigner, and Matthias Gromeier. "Induction of viral, 7-methyl-guanosine cap-independent translation and oncolysis by mitogen-activated protein kinase-interacting kinase-mediated effects on the serine/arginine-rich protein kinase.." J Virol 88, no. 22 (November 2014): 13135–48. https://doi.org/10.1128/JVI.01883-14.
Brown, Michael C., Mikhail I. Dobrikov, and Matthias Gromeier. "Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated translation and viral oncolysis.." J Virol 88, no. 22 (November 2014): 13149–60. https://doi.org/10.1128/JVI.01884-14.
Dobrikov, Mikhail I., Mayya Shveygert, Michael C. Brown, and Matthias Gromeier. "Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.." Mol Cell Biol 34, no. 3 (February 2014): 439–51. https://doi.org/10.1128/MCB.01046-13.
Chandramohan, V., D. A. Mitchell, M. Gromeier, J. H. Sampson, and D. D. Bigner. "Current immunotherapeutic targets in gliomas," May 1, 2013, 287–305.
Dobrikov, Mikhail I., Elena Y. Dobrikova, and Matthias Gromeier. "Dynamic regulation of the translation initiation helicase complex by mitogenic signal transduction to eukaryotic translation initiation factor 4G.." Mol Cell Biol 33, no. 5 (March 2013): 937–46. https://doi.org/10.1128/MCB.01441-12.
Barton, Kelly L., Katherine Misuraca, Francisco Cordero, Elena Dobrikova, Hooney D. Min, Matthias Gromeier, David G. Kirsch, and Oren J. Becher. "PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma.." Plos One 8, no. 10 (2013). https://doi.org/10.1371/journal.pone.0077639.
Lawson, Sarah K., Elena Y. Dobrikova, Mayya Shveygert, and Matthias Gromeier. "p38α mitogen-activated protein kinase depletion and repression of signal transduction to translation machinery by miR-124 and -128 in neurons.." Mol Cell Biol 33, no. 1 (January 2013): 127–35. https://doi.org/10.1128/MCB.00695-12.
Dobrikova, Elena Y., Christian Goetz, Robert W. Walters, Sarah K. Lawson, James O. Peggins, Karen Muszynski, Sheryl Ruppel, et al. "Attenuation of neurovirulence, biodistribution, and shedding of a poliovirus:rhinovirus chimera after intrathalamic inoculation in Macaca fascicularis.." J Virol 86, no. 5 (March 2012): 2750–59. https://doi.org/10.1128/JVI.06427-11.
Goetz, Christian, Elena Dobrikova, Mayya Shveygert, Mikhail Dobrikov, and Matthias Gromeier. "Oncolytic poliovirus against malignant glioma.." Future Virol 6, no. 9 (September 2011): 1045–58. https://doi.org/10.2217/fvl.11.76.
Dobrikov, Mikhail, Elena Dobrikova, Mayya Shveygert, and Matthias Gromeier. "Phosphorylation of eukaryotic translation initiation factor 4G1 (eIF4G1) by protein kinase C{alpha} regulates eIF4G1 binding to Mnk1.." Mol Cell Biol 31, no. 14 (July 2011): 2947–59. https://doi.org/10.1128/MCB.05589-11.
Wang, Eric S., Elena Dobrikova, Christian Goetz, Andrew T. Dufresne, and Matthias Gromeier. "Adaptation of an ICAM-1-tropic enterovirus to the mouse respiratory tract.." J Virol 85, no. 11 (June 2011): 5606–17. https://doi.org/10.1128/JVI.01502-10.
Goetz, Christian, Richard G. Everson, Linda C. Zhang, and Matthias Gromeier. "MAPK signal-integrating kinase controls cap-independent translation and cell type-specific cytotoxicity of an oncolytic poliovirus.." Mol Ther 18, no. 11 (November 2010): 1937–46. https://doi.org/10.1038/mt.2010.145.
Shveygert, Mayya, Constanze Kaiser, Shelton S. Bradrick, and Matthias Gromeier. "Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction.." Mol Cell Biol 30, no. 21 (November 2010): 5160–67. https://doi.org/10.1128/MCB.00448-10.
Neplioueva, Valentina, Elena Y. Dobrikova, Neelanjan Mukherjee, Jack D. Keene, and Matthias Gromeier. "Tissue type-specific expression of the dsRNA-binding protein 76 and genome-wide elucidation of its target mRNAs.." Plos One 5, no. 7 (July 23, 2010). https://doi.org/10.1371/journal.pone.0011710.
Goetz, Christian, and Matthias Gromeier. "Preparing an oncolytic poliovirus recombinant for clinical application against glioblastoma multiforme.." Cytokine Growth Factor Rev 21, no. 2–3 (April 2010): 197–203. https://doi.org/10.1016/j.cytogfr.2010.02.005.
Dobrikova, Elena, Mayya Shveygert, Robert Walters, and Matthias Gromeier. "Herpes simplex virus proteins ICP27 and UL47 associate with polyadenylate-binding protein and control its subcellular distribution.." J Virol 84, no. 1 (January 2010): 270–79. https://doi.org/10.1128/JVI.01740-09.
Walters, Robert W., Shelton S. Bradrick, and Matthias Gromeier. "Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression.." Rna 16, no. 1 (January 2010): 239–50. https://doi.org/10.1261/rna.1795410.
Bradrick, Shelton S., and Matthias Gromeier. "Identification of gemin5 as a novel 7-methylguanosine cap-binding protein.." Plos One 4, no. 9 (September 14, 2009). https://doi.org/10.1371/journal.pone.0007030.
Yang, Xiaoyi, Eying Chen, Hengguang Jiang, Karen Muszynski, Raymond D. Harris, Steven L. Giardina, Matthias Gromeier, Gautam Mitra, and Gopalan Soman. "Evaluation of IRES-mediated, cell-type-specific cytotoxicity of poliovirus using a colorimetric cell proliferation assay.." J Virol Methods 155, no. 1 (January 2009): 44–54. https://doi.org/10.1016/j.jviromet.2008.09.020.
Dobrikova, Elena Y., Trevor Broadt, Judith Poiley-Nelson, Xiaoyi Yang, Gopalan Soman, Steve Giardina, Ray Harris, and Matthias Gromeier. "Recombinant oncolytic poliovirus eliminates glioma in vivo without genetic adaptation to a pathogenic phenotype.." Mol Ther 16, no. 11 (November 2008): 1865–72. https://doi.org/10.1038/mt.2008.184.
Kaiser, Constanze, Elena Y. Dobrikova, Shelton S. Bradrick, Mayya Shveygert, James T. Herbert, and Matthias Gromeier. "Activation of cap-independent translation by variant eukaryotic initiation factor 4G in vivo.." Rna 14, no. 10 (October 2008): 2170–82. https://doi.org/10.1261/rna.1171808.
Everson, Richard G., Michael W. Graner, Matthias Gromeier, James J. Vredenburgh, Annick Desjardins, David A. Reardon, Henry S. Friedman, Allan H. Friedman, Darell D. Bigner, and John H. Sampson. "Immunotherapy against angiogenesis-associated targets: evidence and implications for the treatment of malignant glioma.." Expert Rev Anticancer Ther 8, no. 5 (May 2008): 717–32. https://doi.org/10.1586/14737140.8.5.717.
Selznick, Lee A., Mohammed F. Shamji, Peter Fecci, Matthias Gromeier, Allan H. Friedman, and John Sampson. "Molecular strategies for the treatment of malignant glioma--genes, viruses, and vaccines.." Neurosurg Rev 31, no. 2 (April 2008): 141–55. https://doi.org/10.1007/s10143-008-0121-0.
Cello, Jeronimo, Hidemi Toyoda, Nidia Dejesus, Elena Y. Dobrikova, Matthias Gromeier, and Eckard Wimmer. "Growth phenotypes and biosafety profiles in poliovirus-receptor transgenic mice of recombinant oncolytic polio/human rhinoviruses.." J Med Virol 80, no. 2 (February 2008): 352–59. https://doi.org/10.1002/jmv.21063.
Bradrick, Shelton S., Elena Y. Dobrikova, Constanze Kaiser, Mayya Shveygert, and Matthias Gromeier. "Poly(A)-binding protein is differentially required for translation mediated by viral internal ribosome entry sites.." Rna 13, no. 9 (September 2007): 1582–93. https://doi.org/10.1261/rna.556107.
Florez de Sessions, Paola, Elena Dobrikova, and Matthias Gromeier. "Genetic adaptation to untranslated region-mediated enterovirus growth deficits by mutations in the nonstructural proteins 3AB and 3CD.." J Virol 81, no. 16 (August 2007): 8396–8405. https://doi.org/10.1128/JVI.00321-07.
Everson, Richard G., Mathias Gromeier, and John H. Sampson. "Viruses in the treatment of malignant glioma.." Expert Rev Neurother 7, no. 4 (April 2007): 321–24. https://doi.org/10.1586/14737175.7.4.321.
Campbell, Stephanie A., Matthew Mulvey, Ian Mohr, and Matthias Gromeier. "Attenuation of herpes simplex virus neurovirulence with picornavirus cis-acting genetic elements.." J Virol 81, no. 2 (January 2007): 791–99. https://doi.org/10.1128/JVI.00714-06.
Merrill, Melinda K., and Matthias Gromeier. "The double-stranded RNA binding protein 76:NF45 heterodimer inhibits translation initiation at the rhinovirus type 2 internal ribosome entry site.." J Virol 80, no. 14 (July 2006): 6936–42. https://doi.org/10.1128/JVI.00243-06.
Dobrikova, Elena Y., Rachel N. Grisham, Constanze Kaiser, Jennifer Lin, and Matthias Gromeier. "Competitive translation efficiency at the picornavirus type 1 internal ribosome entry site facilitated by viral cis and trans factors.." J Virol 80, no. 7 (April 2006): 3310–21. https://doi.org/10.1128/JVI.80.7.3310-3321.2006.
Merrill, Melinda K., Elena Y. Dobrikova, and Matthias Gromeier. "Cell-type-specific repression of internal ribosome entry site activity by double-stranded RNA-binding protein 76.." J Virol 80, no. 7 (April 2006): 3147–56. https://doi.org/10.1128/JVI.80.7.3147-3156.2006.
Merrill, M. K., L. A. Selznick, and M. Gromeier. "Oncolytic viruses for the treatment of malignant glioma." Expert Opinion on Therapeutic Patents 16, no. 3 (March 1, 2006): 363–71. https://doi.org/10.1517/13543776.16.3.363.
Ochiai, Hidenobu, Stephanie A. Campbell, Gary E. Archer, Tracy A. Chewning, Eugenia Dragunsky, Alexander Ivanov, Matthias Gromeier, and John H. Sampson. "Targeted therapy for glioblastoma multiforme neoplastic meningitis with intrathecal delivery of an oncolytic recombinant poliovirus.." Clin Cancer Res 12, no. 4 (February 15, 2006): 1349–54. https://doi.org/10.1158/1078-0432.CCR-05-1595.
Bradrick, Shelton S., Robert W. Walters, and Matthias Gromeier. "The hepatitis C virus 3'-untranslated region or a poly(A) tract promote efficient translation subsequent to the initiation phase.." Nucleic Acids Res 34, no. 4 (2006): 1293–1303. https://doi.org/10.1093/nar/gkl019.
Dufresne, A. T., and M. Gromeier. "Understanding polio: New insights from a cold virus." Microbe 1, no. 1 (January 1, 2006): 13–18.
Campbell, Stephanie A., Jennifer Lin, Elena Y. Dobrikova, and Matthias Gromeier. "Genetic determinants of cell type-specific poliovirus propagation in HEK 293 cells.." J Virol 79, no. 10 (May 2005): 6281–90. https://doi.org/10.1128/JVI.79.10.6281-6290.2005.
Florez, Paola M., October M. Sessions, Eric J. Wagner, Matthias Gromeier, and Mariano A. Garcia-Blanco. "The polypyrimidine tract binding protein is required for efficient picornavirus gene expression and propagation.." J Virol 79, no. 10 (May 2005): 6172–79. https://doi.org/10.1128/JVI.79.10.6172-6179.2005.
Moore, S. A., M. K. Merrill, and M. Gromeier. "Treatment of CNS malignancies with a recombinant oncolytic poliovirus." Drug Design Reviews Online 2, no. 3 (May 1, 2005): 233–41. https://doi.org/10.2174/1567269053828774.
Campbell, Stephanie A., and Matthias Gromeier. "Oncolytic viruses for cancer therapy II. Cell-internal factors for conditional growth in neoplastic cells.." Onkologie 28, no. 4 (April 2005): 209–15. https://doi.org/10.1159/000084010.
Campbell, Stephanie A., and Matthias Gromeier. "Oncolytic viruses for cancer therapy I. Cell-external factors: virus entry and receptor interaction.." Onkologie 28, no. 3 (March 2005): 144–49. https://doi.org/10.1159/000083659.
Dufresne, Andrew T., and Matthias Gromeier. "A nonpolio enterovirus with respiratory tropism causes poliomyelitis in intercellular adhesion molecule 1 transgenic mice.." Proc Natl Acad Sci U S A 101, no. 37 (September 14, 2004): 13636–41. https://doi.org/10.1073/pnas.0403998101.
Ochiai, Hidenobu, Stephanie A. Moore, Gary E. Archer, Tatsunori Okamura, Tracy A. Chewning, Jeffrey R. Marks, John H. Sampson, and Matthias Gromeier. "Treatment of intracerebral neoplasia and neoplastic meningitis with regional delivery of oncolytic recombinant poliovirus.." Clin Cancer Res 10, no. 14 (July 15, 2004): 4831–38. https://doi.org/10.1158/1078-0432.CCR-03-0694.
Merrill, Melinda K., Guenter Bernhardt, John H. Sampson, Carol J. Wikstrand, Darell D. Bigner, and Matthias Gromeier. "Poliovirus receptor CD155-targeted oncolysis of glioma.." Neuro Oncol 6, no. 3 (July 2004): 208–17. https://doi.org/10.1215/S1152851703000577.
Scheuner, Donalyn, Matthias Gromeier, Monique V. Davies, Andrew J. Dorner, Benbo Song, Rupali V. Patel, Eckard J. Wimmer, Roger E. McLendon, and Randal J. Kaufman. "The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis.." Virology 317, no. 2 (December 20, 2003): 263–74. https://doi.org/10.1016/j.virol.2003.08.010.
Dobrikova, Elena, Paola Florez, Shelton Bradrick, and Matthias Gromeier. "Activity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3' nontranslated region.." Proc Natl Acad Sci U S A 100, no. 25 (December 9, 2003): 15125–30. https://doi.org/10.1073/pnas.2436464100.
Gromeier, M. "Oncolytic Viruses for Cancer Therapy." American Journal of Cancer 2, no. 5 (November 27, 2003): 313–23. https://doi.org/10.2165/00024669-200302050-00002.
Dobrikova, Elena Y., Paola Florez, and Matthias Gromeier. "Structural determinants of insert retention of poliovirus expression vectors with recombinant IRES elements.." Virology 311, no. 2 (July 5, 2003): 241–53. https://doi.org/10.1016/s0042-6822(03)00191-0.
Fecci, Peter E., Matthias Gromeier, and John H. Sampson. "Viruses in the treatment of brain tumors.." Neuroimaging Clin N Am 12, no. 4 (November 2002): 553–70. https://doi.org/10.1016/s1052-5149(02)00028-x.
Dufresne, Andrew T., Elena Y. Dobrikova, Stacie Schmidt, and Matthias Gromeier. "Genetically stable picornavirus expression vectors with recombinant internal ribosomal entry sites.." J Virol 76, no. 17 (September 2002): 8966–72. https://doi.org/10.1128/jvi.76.17.8966-8972.2002.
Solecki, David J., Matthias Gromeier, Steffen Mueller, Günter Bernhardt, and Eckard Wimmer. "Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog.." J Biol Chem 277, no. 28 (July 12, 2002): 25697–702. https://doi.org/10.1074/jbc.M201378200.
Gromeier, M., and E. Wimmer. "Viruses for the treatment of malignant glioma.." Curr Opin Mol Ther 3, no. 5 (October 2001): 503–8.
Gromeier, M. "Viruses as therapeutic agents against malignant disease of the central nervous system.." J Natl Cancer Inst 93, no. 12 (June 20, 2001): 889–90. https://doi.org/10.1093/jnci/93.12.889.
Chumakov, K., E. Dragunsky, A. Ivshina, J. Enterline, V. Wells, T. Nomura, M. Gromeier, and E. Wimmer. "Inactivated vaccines based on alternatives to wild-type seed virus.." Dev Biol (Basel) 105 (2001): 171–77.
Gromeier, M., D. Solecki, D. D. Patel, and E. Wimmer. "Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: implications for the pathogenesis of poliomyelitis.." Virology 273, no. 2 (August 1, 2000): 248–57. https://doi.org/10.1006/viro.2000.0418.
Gromeier, M., S. Lachmann, M. R. Rosenfeld, P. H. Gutin, and E. Wimmer. "Intergeneric poliovirus recombinants for the treatment of malignant glioma.." Proc Natl Acad Sci U S A 97, no. 12 (June 6, 2000): 6803–8. https://doi.org/10.1073/pnas.97.12.6803.
McCloskey, B. P. "The relation of prophylactic inoculations to the onset of poliomyelitis. 1950.." Rev Med Virol 9, no. 4 (October 1999): 219–26. https://doi.org/10.1002/(sici)1099-1654(199910/12)9:4<219::aid-rmv249>3.0.co;2-t.
Gromeier, M., B. Bossert, M. Arita, A. Nomoto, and E. Wimmer. "Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulence.." J Virol 73, no. 2 (February 1999): 958–64.
Das, S., M. Ott, A. Yamane, W. Tsai, M. Gromeier, F. Lahser, S. Gupta, and A. Dasgupta. "A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element.." J Virol 72, no. 7 (July 1998): 5638–47.
Gromeier, M., and E. Wimmer. "Mechanism of injury-provoked poliomyelitis.." J Virol 72, no. 6 (June 1998): 5056–60.
Das, S., M. Ott, A. Yamane, W. Tsai, M. Gromeier, F. Lahser, S. Gupta, and A. Dasgupta. "Erratum: A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element (Journal of Virology (1998) 72:7 (5638-5647))." Journal of Virology 72, no. 11 (January 1, 1998).
Solecki, D., M. Gromeier, J. Harber, G. Bernhardt, and E. Wimmer. "Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction.." Journal of Molecular Recognition : Jmr 11, no. 1–6 (January 1998): 2–9. https://doi.org/10.1002/(sici)1099-1352(199812)11:1/6<2::aid-jmr380>3.0.co;2-d.
Solecki, D., M. Gromeier, J. Harber, G. Bernhardt, and E. Wimmer. "Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction.." J Mol Recognit 11, no. 1–6 (1998): 2–9. https://doi.org/10.1002/(SICI)1099-1352(199812)11:1/6<2::AID-JMR380>3.0.CO;2-D.
Duggal, R., A. Cuconati, M. Gromeier, and E. Wimmer. "Genetic recombination of poliovirus in a cell-free system.." Proc Natl Acad Sci U S A 94, no. 25 (December 9, 1997): 13786–91. https://doi.org/10.1073/pnas.94.25.13786.
Gromeier, M., S. Mueller, D. Solecki, B. Bossert, G. Bernhardt, and E. Wimmer. "Determinants of poliovirus neurovirulence.." J Neurovirol 3 Suppl 1 (May 1997): S35–38.
Gromeier, M., L. Alexander, and E. Wimmer. "Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants.." Proc Natl Acad Sci U S A 93, no. 6 (March 19, 1996): 2370–75. https://doi.org/10.1073/pnas.93.6.2370.
Gromeier, M., H. H. Lu, G. Bernhardt, J. J. Harber, J. A. Bibb, and E. Wimmer. "The human poliovirus receptor. Receptor-virus interaction and parameters of disease specificity.." Ann N Y Acad Sci 753 (May 25, 1995): 19–36. https://doi.org/10.1111/j.1749-6632.1995.tb27528.x.
Gromeier, M., H. H. Lu, and E. Wimmer. "Mouse neuropathogenic poliovirus strains cause damage in the central nervous system distinct from poliomyelitis.." Microb Pathog 18, no. 4 (April 1995): 253–67. https://doi.org/10.1016/s0882-4010(05)80002-6.
Alexander, L., H. H. Lu, M. Gromeier, and E. Wimmer. "Dicistronic polioviruses as expression vectors for foreign genes.." Aids Res Hum Retroviruses 10 Suppl 2 (1994): S57–60.
Gromeier, M., and K. Wetz. "Kinetics of poliovirus uncoating in HeLa cells in a nonacidic environment.." J Virol 64, no. 8 (August 1990): 3590–97.
Merrill, M., D. Solecki, and M. Gromeier. "Poliovirus recombinants against malignant glioma." In Viral Therapy of Human Cancers, 739–80, 2004.
MGM 293: Research Independent Study I 2020
MGM 593: Research Independent Study 2020
PHARM 394: Research Independent Study 2020


text:
Q: Positioning Buttons on top of Background Image I'm looking to create an effect similar to this: https://www.livestrong.org/donation/
I'm just wondering what ways there are to place images/buttons over top of a background.  Would I just do a class/div with a background and then put the buttons within this div?  I'm not sure if it's that simple but I'd like to make sure I'm on the right track before I delve into this.

A: You you're on the right track.You can use$('#secondDiv').insertBefore('#firstDiv');,assuming you know JS.I'm sure theres a way through CSS, but it probably won't be the best choice. And you can use :active and :hover via CSS for the actual buttons if you try to create that. So when the user hovers on it it'll turn into a light grey, then when they click on it, it'll to a yellow color. Here's an example
#firstbutton:active{
 background:#009dff
}
#firstbutton:hover{
background:#0148A0
 }

redpajama_set_name: RedPajamaStackExchange


DWBA Stone Backless Vanity Stool Bench, Seat White Solid Surface. Very elegant and sleek designed to increase the level of elegance in the room this stool is placed. Maximum weight capacity: 330 LBS. Suitable for shower use, sauna, steam shower - waterproof. Created to offer everlasting beauty with its unique quality and look. Designed in Germany.
- Dimension: 15.7 W x 11 D x 18.1 H in.
Is there a non slip product on the legs? What is the weight of the bench?
Thank you very much for your question, and interest in our DWBA Backless vanity stool.
Yes, this stool comes with a non-slip support in the legs. If you mouse over the main image, you will see a zoom in section which shows the non-slip piece at the bottom of the legs.
The weight of the bench is approximely 25-30 lbs.


text:
Edit Kickstart

Select File

Upload new version
 {{disabled}}

Download File

{{f.name}}


I was getting fed up with poorly designed display stands and inadequate risers so I designed my own riser stand with raindesigns in mind as I love their products.
Giving the second LM 3D Printed vehicle a true 'beach buggy' feel ready for the waves.
Taking the Local Motors Cruiser to the next level with a focus on premium materials.
The Local Motors Cruiser Prototype was made in the fall of 2013 based on the design of Ianis Vasilatos.
One very special car. One very special photo shoot.
Inspired by sailing, sketched in uMake on a boat, perfected in Rhino, rendered in Keyshot. A fun Design exercise.
A design concept for a customizable wheel inspired by nature. Add some Flower Power to your VW and rock the neighborhood in style!
The Local Motors RIG2 Design challenge pushed designers to share their vision for the Road Icon Gen 2 truck to help Peterbilt evolve it's iconic designs for the 21st century.


I downloaded the "Distributive_Gen" file with the two libraries but I am getting an error that says it is unable to execute make. I have PSCAD Professional V 4.31. and GFortran 4.2.1.
First of all, put the text files of library and "Distributive_Gen" file in the same folder. then make sure that ''.f'' files are read correctly by openning them from main page of "Distributive_Gen" file. finally, if the problem still persists, copy the whole folder to desktop and try to run the file from desktop.


text:
General Matthew Duncan Ector
Compiled Military Service Record
Matthew Duncan Ector (Confederate)
Biographical data and notes:
- Born Feb 28 1822 in Putnam County, GA
- Last known address: Texas
- Matthew Duncan Ector died on Oct 29 1879 at Tyler, TX
Enlistment:
- 40 years of age at time of enlistment
- Enlisted as Colonel
Mustering information:
- Commissioned into Field and Staff, 14th Cavalry (Texas)
- Discharged due to promotion from 14th Cavalry (Texas) on Aug 23 1862
- Commissioned into Gen. Staff (Confederate States) on Aug 23 1862
- Promoted to Brig-Gen (Full, Vol) (date not indicated)
- Promoted to Colonel (Full, Vol) (date not indicated) (14th TX Cav)
- Promoted to Adjutant (Full, Vol) (date not indicated)
- Wounded (date not indicated) at Atlanta, GA (Loss of leg)
Sources: General Officers of the Confederate States of America, Confederate Military History, National Archives
Recommended Reading: Ector's Texas Brigade and the Army of Tennessee 1862-1865 (Hardcover). Description: Ector's Texas Brigade served most of the Civil War with the Army of Tennessee. With that battle-riddled command, they wrote an illustrious history upon the pages of American history. "A must read for the student of Texas history, the individual interested in the contributions of Texas in the Civil War, and for that buff that is remotely interested in the Army of Tennessee...[N]o serious study of Texas and the Civil War is possible without this volume."
General Matthew Duncan Ector: Biography
General Matthew Duncan Ector: History, Pictures, Photographs
General Matthew Duncan Ector: Compiled Military Service Record
American Civil War Generals
Confederate Civil War Flag History Homepage
Recommended Reading: Generals in Gray Lives of the Confederate Commanders. Description: When Generals in Gray was published in 1959, scholars and critics immediately hailed it as one of the few indispensable books on the American Civil War. Historian Stanley Horn, for example, wrote, "It is difficult for a reviewer to restrain his enthusiasm in recommending a monumental book of this high quality and value." Here at last is the paperback edition of Ezra J. Warner's magnum opus with its concise, detailed biographical sketches and—in an amazing feat of research—photographs of all 425 Confederate generals. Continued below.
The only exhaustive guide to the South's command, Generals in Gray belongs on the shelf of anyone interested in the Civil War. RATED 5 STARS!
Recommended Reading: Civil War High Commands (1040 pages) (Hardcover). Description: Based on nearly five decades of research, this magisterial work is a biographical register and analysis of the people who most directly influenced the course of the Civil War, its high commanders. Numbering 3,396, they include the presidents and their cabinet members, state governors, general officers of the Union and Confederate armies (regular, provisional, volunteers, and militia), and admirals and commodores of the two navies. Civil War High Commands will become a cornerstone reference work on these personalities and the meaning of their commands, and on the Civil War itself. Continued below...
Errors of fact and interpretation concerning the high commanders are legion in the Civil War literature, in reference works as well as in narrative accounts. The present work brings together for the first time in one volume the most reliable facts available, drawn from more than 1,000 sources and including the most recent research. The biographical entries include complete names, birthplaces, important relatives, education, vocations, publications, military grades, wartime assignments, wounds, captures, exchanges, paroles, honors, and place of death and interment. In addition to its main component, the biographies, the volume also includes a number of essays, tables, and synopses designed to clarify previously obscure matters such as the definition of grades and ranks; the difference between commissions in regular, provisional, volunteer, and militia services; the chronology of military laws and executive decisions before, during, and after the war; and the geographical breakdown of command structures. The book is illustrated with 84 new diagrams of all the insignias used throughout the war and with 129 portraits of the most important high commanders. It is the most comprehensive volume to date...name any Union or Confederate general--and it can be found in here. [T]he photos alone are worth the purchase. RATED FIVE STARS by americancivilwarhistory.org
Recommended Reading: Rebels and Yankees: Commanders of the Civil War (Hardcover), by William C. Davis (Author), Russ A. Pritchard (Author). Description: Davis and Pritchard have created a wonderful work that is sure to become a hit with anyone who studies the Civil War. This book uses words and a generous amount of pictures and photographs to tell the story of the leaders, both talented and flawed, that held together the two struggling armies in a time of chaos and devastating loss. Continued below.
Although many of the stories have been told in one form or another.... Commanders compiles this study in a single book that makes it very easy to compare and contrast the styles and techniques employed by officers of both armies. I thoroughly enjoyed the book and highly recommend it.
Recommended Reading: Battles and Leaders of the Civil War, Volume 6 (Battles & Leaders of the Civil War) (632 pages) (University of Illinois Press) (May 30, 2007). Description: Sifting carefully through reports from newspapers, magazines, personal memoirs, and letters, Peter Cozzens' Volume 6 brings readers more of the best first-person accounts of marches, encampments, skirmishes, and full-blown battles, as seen by participants on both sides of the conflict. Alongside the experiences of lower-ranking officers and enlisted men are accounts from key personalities including General John Gibbon, General John C. Lee, and seven prominent generals from both sides offering views on "why the Confederacy failed." Continued below.
This volume includes one hundred and twenty illustrations, including sixteen previously uncollected maps of battlefields, troop movements, and fortifications.


text:
Richard Bell (* 1953 in Charleville in Queensland, Australien) ist ein Künstler. Geboren wurde er als ein Aborigine vom Stamm der Kamilaroi. Bell gilt als engagierter politischer Künstler und Aktivist für die Rechte der Aborigines, der sich in den letzten Jahren mit seinen Kunstwerken in diese Richtung profiliert hat und damit überaus bekannt geworden ist.

Bell ist ein Künstler, der sich selbst als propagangist bezeichnet, während andere ihn als Enfant terrible, bad boy of Aboriginal art, angry Aboriginal artist bezeichnen.

Leben
Geboren wurde Richard Bell 1953 in Charleville in Queensland. Richard war der älteste Sohn einer Aborigines-Familie mit zwei Söhnen. Sein Vater war ein Zuckerrohrschneider und Viehtreiber, deshalb war er kaum zuhause und die Familie musste häufig umziehen. Als Richard 17 und sein Bruder Marshall 14 Jahre alt waren, starb ihre Mutter. Bevor die beiden Kinder in einem staatlichen Heim untergebracht wurden, nahm sie eine Kusine auf. Richard Bell verließ die High School im zwölften Jahr und begann eine Ausbildung zum Werkzeugmacher in Dalby. Dort blieb er zwei Jahre lang und ging ab 1974 zur Früchteernte nach Tasmanien und Victoria, bis er sich in Redfern niederließ, einem Stadtteil von Sydney.

Über den Rugby-Sportverein All Blacks in Redfern fand er eine Anstellung und kam hierüber in Kontakt zu politischen Bewegungen. Nach einem Aufenthalt von zehn Jahren in Sydney ging er zurück nach Toowoomba und arbeitete als Büroleiter für den Aboriginal Legal Service. Nach dieser Zeit lebte er mit seiner Partnerin Liz Duncan in Moree, nachfolgend bekamen sie zwei Kinder. Richard Bell hatte bereits drei Kinder Adrian, Richard und Deborah. Bell arbeitete in der Pius 10th Aboriginal Corporation, eine Organisation mit einer Vorschule, Zahnklinik und einem Erwachsenen-Bildungszentrum.

Richard Bell zog danach mit seiner Familie nach Brisbane, wo er Gegenstände wie Bumerangs für den Touristenmarkt herstellte. Seine und die Arbeit anderer Künstler boten sie von ihrem gemeinsamen Geschäft 'Wiumulli' in der Zeit von 1987 bis 1990 zum Kauf an. Im Touristikgewerbe blieb Bell bis 1994. Neben Bumerangs gestaltete und stellte Bell auch Postkarten her, die er erfolgreich in Queensland und New South Wales vertrieb. Obwohl er ein tourist artist war, beteiligte er sich an Kunstausstellungen und 1989 schufen Mark Garlett und er das Kunstwerk Rock (art) of Ages, das die Queensland Art Gallery in ihrer Ausstellung Balance 1990 zeigte, sein erster Erfolg als Künstler.

Werk
Bell setzt sich nach seinen eigenen Ausführungen für die Emanzipation und Selbstbestimmung der Aborigines ein und begreift sein Tätigkeitsfeld als ein komplexes künstlerisches und politisches Thema in der westlichen, kolonialen und indigenen Kunstproduktion.

Richard Bell arbeitet mit Video, Malerei, Installation und Text. Dabei greift er mit provokanten, komplexen und humorvollen Herausforderungen vorgefasste Vorstellungen über die Kunst der Aborigines auf und stimuliert dabei gegenwärtige Debatten über Identität, Ort und Politik. Er setzte sich sein ganzes Leben für soziale Gerechtigkeit der Aborigines, ihre Landrechte und ihre Souveränität ein, die er oft mit einer kraftvollen Kritik an der Rechtmäßigkeit der europäischen Invasion Australiens verband.

Bells Arbeiten sind nicht nur eine Reaktion auf Diskriminierung und Rassismus, sondern auch eine Kritik auf den Einsatz der Aborigine-Bildersprache in Werbekampagnen und im Tourismusmarketing etc. Deshalb übernimmt er Stile und Formen der westlichen Moderne, ihren Ausdruck und ihre Ikonografie.

Bekannt wurde Richard Bell als er den Telstra National Aboriginal and Torres Strait Islander Art Award im Jahr 2003 gewann. Sein Werk auf Leinwand enthielt die Phrase "Aboriginal Art – It's a White Thing" ("Aborigines-Kunst – Es ist ein Ding der Weißen"). Als er den Preis entgegennahm, trug er ein T-Shirt mit dem Aufdruck "White girls can't hump" ("Weiße Mädchen können nicht bumsen").

In Bells Gemälden nimmt er die Pop Art von Roy Lichtenstein und Jasper Johns oder die Tropfgemälde von Jackson Pollock auf. In seinen Bildern oder auf T-Shirts bindet er Texte ein, die die Art und Weise, wie über Rassismus und Rassenpolitik gesprochen oder gedacht wird, einbeziehen und infrage stellen. Er klagt die gegenwärtige Kunstwelt an, dass sie die Aboriginal Art manipuliert und ausbeutet.

Auf der documenta fifteen 2022 präsentiert er sein Werk Tent Embassy (Zelt-Botschaft) und nimmt dabei Bezug auf eine politische Protestaktion der Aborigines, die ihren Anspruch auf ihr angestammtes Land Australien mit einer aus Zelten bestehenden Botschaft auf dem Gelände des Old Parliament House in  Canberra seit Jahrzehnten dokumentieren (siehe Zelt-Botschaft). Bell lebt und arbeitet in Brisbane.

Ausstellungen
Vertreten ist Richard Bell in vielen großen nationalen und staatlichen Sammlungen Australiens.
 2021 Einzelausstellung im Museum of Contemporary Art Australia, Sydney
 2019 Biennale di Venezia: Embassy
 2019 Padiglione d'Arte Contemporanea, Mailand: Embassy
 2018 Gertrude Contemporary, Melbourne: Embassy
 2017 Art Gallery of New South Wales, Sydney: Embassy
 2016 Stedelijk Museum, Amsterdam: Embassy
 2016 Einladung zur 20. Biennale of Sydney
 2016 Jerusalem Show VIII
 2015 Performa 15, New York
 2015 Jakarta Biennale
 2015 8. Asia Pacific Triennial of Contemporary Art, Brisbane

Literatur
 Bell, Richard. In: Alan McCulloch, Susan McCulloch, Emily McCulloch: The New McCulloch's encyclopedia of Australian art. 4. Ausgabe. Aus Art Editions in association with The Miegunyah Press, Fitzroy, Victoria 2006, ISBN 0-522-85317-X, S. 39–40.

 Maura Reilly, Richard Bell, Djon Mundine: Richard Bell: Uz Vs them. 1. Ausgabe. American Federation of Arts, London 2011. ISBN 1904832954

Weblinks
 Zahlreiche Arbeiten von Richard Bell, abgebildet auf Artnet
 Zahlreiche Bilder und Text (englisch) zur weltweiten Vorstellung von Zelt-Botschaften durch Richard Bell

 Pay the Rent, Abbildung seiner Arbeit aus 2009 mit Text (englisch)
 Interview mit Richard Bell anläßlich der Verleihung des Telstra-Preises (englisch)
 Interviews mit und Literatur über Richard Bell (englisch)

Einzelnachweise

Maler (Australien)
Kunst der Aborigines
Künstler (documenta)
Australier
Geboren 1953
Mann


Both versatile and environmentally friendly, Montana Colors Water Based is a revolutionary formula with excellent characteristics: long durability, fast drying, high-quality matte finish, and totally free of lead and heavy metals. The pigments used have a great fastness to light, giving the finished color durability on outdoor exposure, while its water-based resins mean low odor, making this spray paint an ideal choice for interior use in spaces with poor ventilation.
Buy in bulk! Explore the Paint Packs we have.


The University of Denver's Daniels College of Business has launched an online MBA program which will allow students to study remotely while keeping up with work commitments.
The [email protected] curriculum will be the same as that of the on-campus MBA, but students will connect virtually for weekly classes. Between the weekly sessions, students will study using interactive content online.
In that way, students will be able to study for the MBA without having to relocate away from family and work commitments.
There will still be opportunities for students to meet face-to-face for more immersive study activities. These will include leadership training, as well as networking opportunities with entrepreneurs, corporate partners, peers and faculty.
The University of Denver will run the new program in partnership with education technology company 2U.


Guantanamo by Outlandish, brilliant song.
State Radio performing live in DC. Watch the full concert at http://www.tenthrow.com in High Definition.
State Radio is a Boston-based rock trio comprising singer and primary songwriter Chad Stokes Urmston (also a member of Dispatch), bassist Chuck Fay, and, formerly, drummer Michael Najarian. The band's songs focus on social and political issues and have been musically described as a combination of reggae, punk and rock.
Chad Urmston, whose previous band Dispatch disbanded in 2002, formed State Radio later the same year in Sherborn, Massachusetts with second guitarist Pete Halby, bassist Chuck Fay, and drummer Mike Greenfield. The band, originally known as Flag of the Shiners, released an eponymous debut EP on Fenway Recordings in late 2002. The EP was later re-released under the band's current name, however the title remained the same.
State Radio went on a temporary hiatus throughout 2003 as Urmston recovered from throat surgery. They returned to touring and recording in 2004 as a slimmed-down trio with new drummer Brian Sayers. The band released a second EP entitled Simmer Kane in March 2004. This EP was a departure in style from the debut EP Flag of the Shiners as it featured acoustic guitar and Erin Lashnits Coughlin ("Ras LC") on vocals. In December 2005, State Radio released its first LP, Us Against the Crown. After touring for a few months in support of this album, drummer Michael Najarian was brought in to replace Brian Sayers, playing his first show at Emo's in Austin, Texas. With this lineup, the band recorded and released their second album Year of the Crow in September 2007.


ACEND® UPdate was created as a periodic web-based communication tool to keep the ACEND®-accredited program directors, the dietetics education community and the public up-to-date on important events and activities.
The ACEND® UPdate (formerly the ACEND® Newsletter) is copyrighted, but may be reproduced in whole or in part in the interest of education. Program directors should share this information with faculty and staff.


text:
Q: Python and regex - how to find anytext_NUMBER_svm.pkl I have file names that are in this format:
anytext_NUMBER_svm.pkl

I need to loop thourgh all files in a dir and file files that look like this:
file1.txt
file2.txt
anytext_1_svm.pkl
anytext_2_svm.pkl
anytext_3_svm.pkl

The matched files will be this:
anytext_1_svm.pkl
anytext_2_svm.pkl
anytext_3_svm.pkl

How to I use python regex to do this?

A: An option that:

*

*doesn't use re

*makes sure the comparison is only on the filename part - not part of a path

*restricts the number of filename patterns to validate further using iglob
Code:
from glob import iglob
import os.path
for fname in iglob('*_*_svm.pkl'):
    path, name = os.path.split(fname)
    anytext, digit, rest = name.split('_', 2)
    if digit.isdigit(): # add criteria for anytext if required...
        # ....

A: This regex shoud solve your problems:
>>> import re
>>> regex = re.compile(r'.+_\d+_svm\.pkl')
>>> regex.search('anytext_1_svm.pkl') != None
True

But you should definitely take a look at the documentation: http://docs.python.org/library/re.html

A: regex to catch "anytext_NUMBER_svm.pkl" is very simple.
r'.+_\d+_svm\.pkl'

A: I would suggest a review of this page:
http://docs.python.org/py3k/library/re.html#module-re
It will help you understand how to write regular expressions and ensure that you are matching things properly.  For the number, use [0-9]*, use _ to separate your groups, and write a little match-checking conditional stuff and this will be a quick project.

A: import glob
file_list = glob.glob('anytext_[0-9]_svm.pk1')


I couldn't be more pleased and proud of what we've accomplished thus far on our journey into the Toronto theatre scene. We've come a long way in just a few short months and I think I'm comfortable saying we not only reached our goal, but did it well.
What started out as just an idea to do a small, local theatre production, quickly escalated into a double bill show with a debut party. Not quite sure how it became so complex, but we have no small ideas, so I apologise for none of it.
Featuring Jeremy Panda, who performed live acoustic guitar music for us, and delicious catered (and Bony Fiddle themed!) desserts by Chi's Cakes, it was a fantastic kick-off to the first night of the show at the Tranzac Theatre. Thanks Chi and Jeremy!
A big, Bony Fiddle skull nod to our amazing FX make-up team of Sean George, Eleanor MacVeigh, and Eden Kontrimas (right). The energy and attention they threw into creating the zombies for Lost Refuge added a whole other layer of awesome.
Zombies walking through the crowd and up onto the stage went over really well with the audience during each show and were a big hit. Not to mention, the team pulled off some undead miracles and created us some of the nicest looking zombies I've ever seen. And I can't believe they did it for us. You guys rock!
Samantha Willison, Marina Pratt, and Jasmine Nichols not only helped keep us on track, but more importantly kept us co-ordinated with their adept handling of all our back stage operations and our stage crew. Couldn't have done it without you!
Original music and sound effects were created by Ryan Bower who kept the sound board along with Samantha during all performances. Ryan was with us from the start and working on the music months ahead of auditions when planning was still preliminary. Props for hanging in there, Ryan, even through the computer problems. Oh, and in case you forgot? No one cares about your golf, Ryan!
Although we didn't fill the house every night, which would have been too good to be true for our first show, I consider this a huge success for Bony Fiddle and our live performance crew. Feedback from theatre goers was quite positive all around and everyone who worked on the show should feel very proud of themselves.
We even had the pleasure of being reviewed by Daniel Rostas at Mooney on Theatre and the review he gave us couldn't have been better, especially on our first time out. It tells me we're on the right path and doing the right thing. The cast and crew know how I feel – they've already requested a cast party 3.0!
It's been a very enjoyable summer, one of the best, and we've learned a lot along the way. We've also met some amazing people that we'll be working with again and feel like some true friendships were made not only between myself and everyone involved, but within the cast and crew, as well. It's no easy feat to put on a show in just six months, and with everyone's help, we did a wonderful thing here.
We brought people together and we made art.


Jim's and SMGA's efforts have been recognized by numerous media outlets. Jim was awarded the prestigious (2010) PGA Patriot Award for his contributions to the recovery of wounded veterans. The following 2004 article from ESPN.com tell how several trips from Walter Reed Army Medical Center to Olney Golf Park, where Jim Estes is a PGA Teaching Professional, eventually evolved into a 501(c)(3) non-profit corporation aimed at supporting post-9/11 wounded veterans.