In conformity with article 13 of the above-mentioned Legislative Decree, we wish to inform you that Antico Borgo San Martino processes the ordinary personal data of its customers and suppliers and those subjects who have voluntarily provided their registration data, directly or by telephone, fax or e-mail, to our sales office or the company that does telemarketing for us.
In conformity with the law (article 2 – Purposes), Antico Borgo San Martino guarantees that your personal data will be processed with respect for the rights, fundamental liberties and dignity of the interested party, with particular reference to confidentiality, personal identity and the right to the protection of personal data.
shipping companies, fax, e-mail and the private areas of the web site of Lungarno Alberghi Srl.
For those subjects who intend to open a commercial relationship with our company, even if purely for the purpose of obtaining information about our activities/services, providing personal data is optional; however, a failure to provide the information could make it impossible to continue the relationship, conduct it properly or fulfil legal and even tax obligations. The data are kept at our company's operating headquarters for the time required by civil and tax regulations.
The personal data is exclusively processed at the headquarters of Antico Borgo San Martino using paper and computer media, using both the telephone and computers and even using automated equipment for the storage, handling and transmission of the data, taking every precaution to guarantee its security and confidentiality.
The personal data collected through the online services provided by Antico Borgo San Martino will be held and stored in the headquarter. All personal information is processed exclusively by technical staff specifically employed for this purpose and, occasionally, by maintenance personnel.
the processing of personal data that regards him for the purpose of sending advertising or direct sales material or for market research or commercial communications.
The above rights may be exercised by an informal request to the owner, or one of the managers, even through an agent, and will be acknowledged without delay. A request may be sent to the owner or manager via registered letter, fax or e-mail.
to the attention, also as regards their content, of those to whom the data was communicated or published, except in the case where such fulfilment is impossible or involves a use of means that is obviously disproportionate to the right protected.
Specific security measures have been taken by the site to provide secure access and protect the information contained in the private area from the risks of loss or accidental destruction, unauthorised access or processing that is not allowed or does not conform to the purposes for which it was collected.
The antivirus software is updated automatically. Clients are assigned a username and password for access to the private area. The latter are assigned and communicated in a confidential way to the person designated by the client, if an agency or company, or to the client himself, if a physical person. The user is obligated to keep the username and password confidential.


If the DBMS supports transaction, the transaction will work by default; then, when you launch the app, it is already working.
The framework starts the transaction just before the action is called, and after being called, it commits the transaction.
If something abnormal occurs and you want to roll back the transaction, you can throw an exception or call rollbackTransaction() method in the controller. A Rollback should be implemented after completing the action.
If you don't want to activate the transaction itself deliberately, you can override the transactionEnabled() method of the controller and then return false.
You can set each controller, as in this example, or, if you don't want to use it all, you can override in ApplicationController.


Time Warner Cable Mid-Ohio announced today the lineup for high school football coverage for Friday, Aug. 31.
This week's coverage: Marion Franklin at Pickerington Central and Hilliard Darby at Hilliard Davidson.
Digital subscribers statewide can find the games on Channel 311 and 1311 (in HD), and they'll also have the ability to view replays on Local On Demand channel 411 (local analog listings are below). While games will occasionally air live, most will be televised the same day they are played.
Date Teams Times Fri., Aug. 31 Marion-Franklin at Pickerington Central 10 p.m. Fri., Aug. 31 Hilliard Darby at Hilliard Davidson 12:30 a.m.


text:
Volume 27, Number 8—August 2021
Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany
Coronavirus Vaccine Breakthrough Infections
Effectiveness of mRNA BNT162b2 Vaccine, Israel
More articles on Vaccine, Immunization
Tatjana Schwarz1, Pinkus Tober-Lau1, David Hillus, Elisa T. Helbig, Lena J. Lippert, Charlotte Thibeault, Willi Koch, Irmgard Landgraf, Janine Michel, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Chantip Dang-Heine, Stefanie Kasper, Friederike Münn, Kai Kappert, Andreas Nitsche, Rudolf Tauber, Sein Schmidt, Piotr Kopankiewicz, Harald Bias, Joachim Seybold, Christof von Kalle, Terry C. Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander2 , Victor M. Corman2 , and Florian Kurth2
Author affiliations: Charité–Universitätsmedizin Berlin, Berlin, Germany (T. Schwarz, P. Tober-Lau, D. Hillus, E.T. Helbig, L.J. Lippert, C. Thibeault, W. Koch, L. Bergfeld, D. Niemeyer, B. Mühlemann, C. Conrad, C. Dang-Heine, S. Kasper, F. Münn, K. Kappert, R. Tauber, S. Schmidt, P. Kopankiewicz, H. Bias, J. Seybold, C. von Kalle, T.C. Jones, N. Suttorp, C. Drosten, L.E. Sander, V.M. Corman, F. Kurth); Hausarztpraxis am Agaplesion Bethanien Sophienhaus, Berlin (I. Landgraf); Robert Koch Institute, Berlin (J. Michel, A. Nitsche); German Centre for Infection Research, Berlin (D. Niemeyer, B. Mühlemann, T.C. Jones, C. Drosten, V.M. Corman); Berlin Institute of Health, Berlin (C. Dang-Heine, K. Kappert, R. Tauber, S. Schmidt, J. Seybold, C. von Kalle); Labor Berlin–Charité Vivantes GmbH, Berlin (K. Kappert, R. Tauber); University of Cambridge, Cambridge, UK (T.C. Jones); G; erman Center for Lung Research, Gießen, Germany (N. Suttorp, L.E. Sander, F. Kurth); Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany (F. Kurth); University Medical Centre Hamburg-Eppendorf, Hamburg (F. Kurth)
We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has led to an urgent need for vaccines, particularly among persons at high risk for severe disease and death, such as the elderly (1). Efficacy against severe coronavirus disease (COVID-19) of mRNA vaccine BNT162b2 (Pfizer-BioNTech, https://www.pfizer.com) is reported to be >90% starting 7 days after the second vaccination; robust antibody and T-cell response has been demonstrated consistently across age groups (2–4). However, only 4.3% of participants in the BNT162b2 efficacy trial were >75 years of age (4). Given the elderly generally have weaker immune responses after vaccination, more detailed investigation is necessary (4,5).
In a prospective observational cohort study, we investigated SARS-CoV-2–specific antibodies, maturation of IgG avidity, and interferon-γ (IFN-γ) release of SARS-CoV-2–specific T cells in 2 cohorts of young and elderly BNT162b2-vaccinated persons (Table). Participants were recruited from 2 studies conducted at Charité–Universitätsmedizin Berlin, both conducted in accordance with the Declaration of Helsinki and Good Clinical Practice (https://www.ema.europa.eu/en/documents/scientific-guideline/ich-e-6-r2-guideline-good-clinical-practice-step-5_en.pdf) and approved by the local ethics committee (EA4/244/20 and EA4/245/20)
The first cohort consisted of 123 healthcare workers; median age was 34 (interquartile range [IQR] 20–64) years. The second cohort consisted of 71 elderly residents of an assisted living facility; median age was 81 (IQR 70–96) years. Blood samples were taken before the first vaccination (week 0), just before the second vaccination (week 3), and 4 weeks after the second vaccination (week 7). To discriminate between vaccine-induced antibody response and convalescent SARS-CoV-2 infection, we used the SeraSpot Anti-SARS-CoV-2 IgG microarray-based immunoassay including nucleocapsid and spike as antigens (Seramun Diagnostica GmbH, https://www.seramun.com) (Appendix). Ten of 123 healthcare workers and 1 of 71 elderly participants showed reactive anti-nucleocapsid or anti-spike IgG before the first vaccination and were excluded from further analyses.
Figure. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific antibody and T-cell response after vaccination with BNT162b2 (Pfizer-BioNTech, https://www.pfizer.com) in the elderly, Germany. A) SARS-CoV-2 RBD IgG measured in serum...
At week 3, in the younger cohort, 93/107 (86.9%, 95% CI 79.2%–92.0%) participants showed reactive SARS-CoV-2 receptor-binding domain (RBD) IgG, compared with only 16/52 elderly participants (30.8%, 95% CI 19.9%–44.3%). At week 7, the antibody response rate had increased in both cohorts, to 112/113 in younger participants (99.1%, 95% CI 95.2%–100.0%) and 64/70 in the elderly cohort (91.4%, 95% CI 82.5%–96.0%) (Figure, panel A; Appendix Table). The comparison of SARS-CoV-2 RBD IgG levels demonstrated a significant difference in the 2 cohorts at both week 3 (p<0.0001) and week 7 (p = 0.0003) (Appendix Table), indicating a substantial delay and overall reduced antibody response in elderly participants. We observed similar kinetics and differences between cohorts for antibody responses to 2 further SARS-CoV-2 spike antigens: the S1 subdomain and the full spike protein (Appendix Table, Figure).
We further confirmed the delayed and reduced antibody response in the elderly by measurement of the functional neutralization capacity using the surrogate virus neutralization test (sVNT) cPass (medac GmbH, https://international.medac.de) (Appendix) (6). At week 3, only 24/52 elderly participants (46.2%, 95% CI 33.3%–59.5%) had neutralizing capacity in serum, compared with 97/107 younger participants (90.7%, 95% CI 83.7%–94.8%; p<0.0001 (Figure). In addition, the median sVNT titer for elderly participants was significantly lower than the young cohort (26.4% [IQR 6.8%–40.9%] vs. 60.2% [IQR 45.0%–76.4%]; p<0.0001) (Appendix Table). Although the neutralizing antibody response rate increased to 63/70 (90.0%, 95% CI 80.8%–95.1%) in elderly participants by week 7, the median sVNT titer remained significantly lower than in the younger cohort (89.6% [IQR 70.9%–95.2%] vs. 96.7% [IQR 95.6%–97.2%]; p<0.0001) (Appendix Table).
To characterize the maturation of IgG avidity in all 16 elderly and 30 randomly selected younger participants who were seroreactive at week 3, we applied a modified SARS-CoV-2 S1 IgG ELISA (Euroimmun, https://www.euroimmun.com) (Appendix Figure 2). The delayed antibody response in the elderly is reflected in results: at week 7, only 8/16 elderly (50.0%, 95% CI 28.0%–72.0%) exhibited high S1 IgG avidity indices (>60) compared with 28/30 young participants (93.3%, 95% CI 78.7%–98.8%) (Figure, panel C). Consequently, the median relative avidity index of IgG was significantly higher in the younger cohort than the elderly cohort (76.2% [IQR 67.6%–82.9%] vs. 59.3% [IQR 55.3%–68.9%]; p = 0.0002) (Figure, panel C).
In addition to antibody responses, we assessed SARS-CoV-2 spike-specific T cell responses by an IFN-γ release assay (IGRA) (Euroimmun) (Appendix) of S1 peptide-stimulated T cells at week 7. The proportion of persons with IGRA results above the defined threshold (Appendix) was significantly lower in the elderly than in younger participants (51.2% [95% CI 36.8%–65.4%] vs. 84.5% [95% CI 74.4%–91.1%]; p = 0.0002). Accordingly, median S1-induced IFN-γ release was significantly decreased in the elderly compared to younger participants (707.3 mIU/mL [IQR 216–1,392] vs. 2184 mIU/mL [IQR 1,274–2,484]; p<0.0001) (Figure, panel D). In contrast, we detected no significant difference in IFN-γ release after mitogen stimulation between the 2 cohorts, indicating no general impairment of IFN-γ responses in the elderly (p = 0.77) (Figure, panel D; Appendix Table).
In summary, vaccination with BNT162b2 induces both arms of adaptive immunity: SARS-CoV-2–specific antibodies and SARS-CoV-2–specific T cells. However, we observed delayed and less robust cellular and humoral immune response among the elderly than among younger adults. A limitation of our study is the lack of data on other COVID-19 vaccines. Furthermore, we cannot exclude that underlying diseases or medications, which are more common in the elderly (Table), might impair the vaccine-induced immune response. For example, patients on dialysis have significantly lower antibody response than vaccinated same-age patients not on dialysis (E. Schrezenmeier et al., unpub. data, http://medrxiv.org/lookup/doi/10.1101/2021.03.31.21254683).
Our data are supported by other real-world observations suggesting a delayed and reduced immunogenicity of BNT162b2 in the elderly (5,7; D.A. Collier et al., unpub. data, http://medrxiv.org/lookup/doi/10.1101/2021.02.03.21251054). In line with our observations for BNT162b2, an effect of age-dependent decrease of immune function, referred to as immunosenescence, is well known and contributes to increased prevalence of infectious disease and vaccine failure in the elderly (8). A lower vaccine-induced immune response to influenza and hepatitis B viruses is well documented (9,10); however, such data are scarce for mRNA vaccines.
Of note, vaccination with 2 doses of BNT162b2 might not fully prevent SARS-CoV-2 outbreaks among elderly persons in congregate settings, such as long-term care facilities, possibly because of delayed and reduced immune response. However, vaccination protects against severe disease (11–13).
Although the immune response of elderly participants 4 weeks after the second dose of BNT162b2 nearly reached the level of younger participants, a small fraction of elderly participants did not demonstrate robust antibody and T-cell response. However, the immunologic correlates of protection remain unknown, and identification of persons with no or incomplete protection after vaccination remains challenging. Therefore, strategies focused solely on vaccinating of high-risk groups might be insufficient to protect those at risk for severe disease. For the elderly, vaccination of caregivers and close contacts should be prioritized. Moreover, a booster vaccination, altered vaccine dose, or different COVID-19 vaccines should be considered for the elderly if further evidence demonstrates high rates of breakthrough infections despite 2-dose BNT162b2 vaccination.
These results are particularly relevant for vaccination strategies focused on broad administration of the first dose of a 2-dose vaccine while postponing the second vaccination. This practice might leave a relevant proportion of elderly with comparatively low levels of immunity for a prolonged period, emphasizing the need for nonpharmaceutical interventions, such as mask use and regular testing.
Dr. Schwarz is a postdoctoral researcher in the Institute of Virology, Charité–Universitätsmedizin Berlin, Berlin, Germany. Her research interests include infectious disease surveillance and immunologic testing.
We thank Marie Luisa Schmidt, Patricia Tscheak, Julia Tesch, Johanna Riege, Petra Mackeldanz, Felix Walper, Jörn Ilmo Beheim-Schwarzbach, Tobias Bleicker, Sevda Senaydin, Doris Steuer, André Solarek, Viktoria Schenkel, Ute Gläser, Anne-Sophie Sinnigen, Carolin Rubisch, Nadine Olk, Lisbeth Hasler, Angela Sanchez-Rezza, Paolo Kroneberg, Alexandra Horn, Lara Bardtke, Kai Pohl, Daniel Wendisch, Philipp Georg, Denise Treue, Dana Briesemeister, Jenny Schlesinger, Luisa Kegel, Annelie Richter, Ben Al-Rim, Birgit Maeß, Hana Hastor, Maria Rönnefarth, and Alexander Krannich for excellent assistance and biobanking of samples
Parts of this work were supported by grants from the Berlin Institute of Health (BIH). This study was further supported by the German Ministry of Research through the projects VARIPath (01KI2021) to V.M.C., and NaFoUniMedCovid19-COVIM, FKZ: 01KX2021 to L.E.S., F.K., C.D., and V.M.C., and by the RECOVER project (European Union Horizon 2020 research and innovation program; GA101003589) to C.D. T.C.J. is in part funded through NIAID-NIH CEIRS contract HHSN272201400008C. V.M.C. is a participant in the BIH–Charite Clinician Scientist Program funded by the Charite–Universitätsmedizin Berlin and BIH.
V.M.C. is named together with Euroimmun GmbH on a patent application filed recently regarding SARS-CoV-2 diagnostics via antibody testing.
Brown AE, Heinsbroek E, Kall MM, Allen H, Beebeejaun K, Blomquist P, et al.; PHE COVID-19 Mortality Working Group. Epidemiology of confirmed COVID-19 deaths in adults, England, March–December 2020. Emerg Infect Dis. 2021;27:1468–71. DOIPubMedGoogle Scholar
Walsh EE, Frenck RW Jr, Falsey AR, Kitchin N, Absalon J, Gurtman A, et al. Safety and immunogenicity of two RNA-based Covid-19 vaccine candidates. N Engl J Med. 2020;383:2439–50. DOIPubMedGoogle Scholar
Dagan N, Barda N, Kepten E, Miron O, Perchik S, Katz MA, et al. BNT162b2 mRNA Covid-19 vaccine in a nationwide mass vaccination setting. N Engl J Med. 2021;384:1412–23. DOIPubMedGoogle Scholar
Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al.; C4591001 Clinical Trial Group. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. N Engl J Med. 2020;383:2603–15. DOIPubMedGoogle Scholar
Van Praet JT, Vandecasteele S, De Roo A, De Vriese AS, Reynders M. Humoral and cellular immunogenicity of the BNT162b2 mRNA Covid-19 Vaccine in nursing home residents. Clin Infect Dis. 2021;ciab300; Epub ahead of print. DOIPubMedGoogle Scholar
Tan CW, Chia WN, Qin X, Liu P, Chen MI-C, Tiu C, et al. A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction. Nat Biotechnol. 2020;38:1073–8. DOIPubMedGoogle Scholar
Müller L, Andrée M, Moskorz W, Drexler I, Walotka L, Grothmann R, et al. Age-dependent immune response to the Biontech/Pfizer BNT162b2 COVID-19 vaccination. Clin Infect Dis. 2021;ciab381; Epub ahead of print. DOIPubMedGoogle Scholar
Crooke SN, Ovsyannikova IG, Poland GA, Kennedy RB. Immunosenescence and human vaccine immune responses. Immun Ageing. 2019;16:25. DOIPubMedGoogle Scholar
Fisman DN, Agrawal D, Leder K. The effect of age on immunologic response to recombinant hepatitis B vaccine: a meta-analysis. Clin Infect Dis. 2002;35:1368–75. DOIPubMedGoogle Scholar
McElhaney JE, Verschoor CP, Andrew MK, Haynes L, Kuchel GA, Pawelec G. The immune response to influenza in older humans: beyond immune senescence. Immun Ageing. 2020;17:10. DOIPubMedGoogle Scholar
Cavanaugh AM, Fortier S, Lewis P, Arora V, Johnson M, George K, et al. COVID-19 outbreak associated with a SARS-CoV-2 R.1 lineage variant in a skilled nursing facility after vaccination program—Kentucky, March 2021. MMWR Morb Mortal Wkly Rep. 2021;70:639–43. DOIPubMedGoogle Scholar
Teran RA, Walblay KA, Shane EL, Xydis S, Gretsch S, Gagner A, et al. Postvaccination SARS-CoV-2 infections among skilled nursing facility residents and staff members—Chicago, Illinois, December 2020–March 2021. MMWR Morb Mortal Wkly Rep. 2021;70:632–8. DOIPubMedGoogle Scholar
Tober-Lau P, Schwarz T, Hillus D, Spieckermann J, Helbig ET, Lippert LJ, et al. Outbreak of SARS-CoV-2 B.1.1.7 lineage after vaccination in long-term care facility, Germany, February–March 2021.[ [Epub ahead of print]. Emerg Infect Dis. 2021; (Jun):XX.
Figure. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific antibody and T-cell response after vaccination with BNT162b2 (Pfizer-BioNTech, https://www.pfizer.com) in the elderly, Germany. A) SARS-CoV-2 RBD IgG measured in serum of...
Table. Cohort characteristics in study of delayed antibody and T-cell response to BNT162b2 vaccination in the elderly, Germany
Original Publication Date: June 08, 2021
1These authors contributed equally to this article.
2These senior authors contributed equally to this article.
Table of Contents – Volume 27, Number 8—August 2021
Victor M. Corman, Leif Erik Sander, and Florian Kurth, Charité–Universitätsmedizin Berlin, Chariteplatz 1, D-10117, Berlin, Germany
Page created: June 02, 2021
Page updated: July 18, 2021
Page reviewed: July 18, 2021
August 2021expand
Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germanyexpand
Schwarz T, Tober-Lau P, Hillus D, Helbig ET, Lippert LJ, Thibeault C, et al. Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany. Emerg Infect Dis. 2021;27(8):2174-2178. https://doi.org/10.3201/eid2708.211145
Schwarz T, Tober-Lau P, Hillus D, et al. Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany. Emerging Infectious Diseases. 2021;27(8):2174-2178. doi:10.3201/eid2708.211145.
Schwarz, T., Tober-Lau, P., Hillus, D., Helbig, E. T., Lippert, L. J., Thibeault, C....Kurth, F. (2021). Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany. Emerging Infectious Diseases, 27(8), 2174-2178. https://doi.org/10.3201/eid2708.211145.
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redpajama_set_name: RedPajamaCommonCrawl


text:
Published in the La Vernia News on March 19, 2015
It's a Blast!
Challenger Learning Center offers an out-of- this world experience
There are a total of 44 Challenger Learning Centers throughout the United States, Canada, the United Kingdom, and South Korea. But the center at the Scobee Planetarium on the campus of San Antonio College is on the cutting edge in advanced technology. The amazing programs that they offer here are geared to engage young minds in all areas of science, technology, engineering, and math (STEM).
The core of each Challenger Learning Center is an interactive computerized simulator with a Mission Control room patterned after the NASA Johnson Space Center and an orbiting space station ready for exploration. These hands-on facilities give students the chance to participate in dynamic simulated space missions and cultivate the skills needed for future success through teamwork and problem solving. It is befitting that this Learning Center was relocated after 10 years at the Brooks City Base to the newly renovated Scobee Planetarium. According to Bob Kelley, Planetarium Coordinator, "This is where it was meant to be."
This very special program targets 5th to 8th grade students to participate in a simulated space mission. School districts have to submit a request for a specific date. The cost to the district is $500.00 (approximately $15 per student) and the Learning Center can schedule up to eight "missions" each week led by a seasoned Flight Director. Each mission starts with a group of 32 students, chosen by their teachers, who also have to undergo training prior to the event to prepare their students. The 2½ hour mission begins with a NASA-style briefing; half of students proceed to Mission Control, dawn official looking badges, and are assigned to one of the station such Communications, Weather, Energy, Oceanography, and Cryogenics, just to name a few. With a push of a button, computers rise from the center of their workstations and their journey begins.
The other students slip into their space vests, enter into the transporter for their trip up to the space station. The transporter simulates the sights, sounds, and all the sensations of a blastoff from earth, the quietness of space, and then the distinctive thud of docking with the orbiting station. After docking, the crew enters the space station via an airlock and then a decontamination room. Once inside the space station, their "work" begins. Working together with Mission Control, there are many tasks that have to be performed and experiments that have to be accomplished.
Half way into the mission, there is an emergency - lights start flashing, emergency signs flash on all the computers, and sirens go off. "We must get the crew back from the space station." Back into the transporter, the Space Station Crew prepares for their return trip back to earth. Arriving at Mission Control, the emergency is resolved. This is the perfect time to switch crews - the Mission Control crew goes back up to the space station and the crew that just returned takes over Mission Control.
One of the major tasks for both crews is the building of a satellite that must be launched. Using remote cameras, Mission Control guides the Space Station Crew through a series of steps to assemble the satellite. Teamwork is essential to have a successful launch of the satellite and therefore, a successful mission, just like the astronauts.
As we were mesmerized with the idea of space travel, Bob Kelley mentioned that at the end of a mission, one of the young participants asked him, "Did we really go into space?" That is how real the experience is, thanks to a well-trained staff, and all the Disney-type special effects. This is more than a game - more than a day off from school. This program is inspiring curiosity in the minds of our future explorers.
Because there has been so much excitement about this Challenger Learning Center, there is also a plan to offer this experience to the general public. The first foray into this plan is a Valentine's Day Wine and Cheese Couples Mission that was offered on the center's website in late January and sold out in three days. Mr. Kelley told us that there are more special events planned for the future, possibly a Mother's Day and Father's Day Mission, and definitely a Halloween Mission, where participants are invited to come as their favorite alien. There will be a charge for these special programs - but the experience will be priceless. We are already in line!
The Challenger Learning Center is located on the San Antonio Collage Campus, 1300 San Pedro Avenue, (210) 486-0100, Website: www.alamo.edu/sac/planetarium/
Best way to keep current with activities & programs: Scobee Planetarium's Facebook page
General Information on the Challenger Centers worldwide: www.challenger.org
10 9 8 7 6 . . .


text:
Chickenpox cluster reported in Summit County, Colorado
By NewsDesk @bactiman63
Summit County Public Health has identified a cluster of varicella cases. Varicella, or more commonly, "chickenpox", is a very contagious disease caused by the varicella-zoster virus (VZV) that is spread from person-to-person by coughing and sneezing, or by touching the fluid from a varicella lesion. Ten cases have been reported to public health since August. The majority of the cases are among children who attend school in Summit County and who have not received the varicella vaccine. The varicella vaccine is routinely given in two doses, with the first dose at age 12 to 15 months and the second dose at age 4 to 6 years. To attend school in Colorado, students must have received two doses of the varicella vaccine or have a signed exemption form on file with their school.
A number of varicella, or chickenpox lesions on the face of a young child/CDC
Symptoms of varicella include an itchy, blister-like rash; fever; tiredness; and loss of appetite. Varicella is usually not serious, but it may cause severe illness in some people such as infants; pregnant people, who never had chickenpox or the chickenpox vaccine; people with weakened immune systems; and people with chronic skin or lung conditions.
Summit School District (SSD) sent notifications to parents of students who may have been exposed at Summit Middle School (SMS) and Dillon Valley Elementary School (DVE). Parents of unvaccinated children who may have been exposed to varicella have been contacted by phone by SSD and Summit County Public Health (SCPH). SCPH and school-based health centers have provided varicella vaccines to several children to reduce the spread of the virus. While varicella can occur in people who have been vaccinated and who have had varicella in the past, vaccination is the best way to prevent the spread of disease.
"We are sorry to report these cases among these young members of our school district," Summit County Public Health Nurse Manager Lauren Gilbert said. "We are working closely with Summit School District to ensure students receive the appropriate care and to minimize further spread of the disease. This is a reminder that we have other preventable communicable diseases that can circulate in our community"
SCPH expects that the high varicella vaccination rates in Summit County will help the disease from spreading further.
In Dillon Valley Elementary, 88.33% of kindergartens and 90.61% of all students have been fully vaccinated against varicella
In Summit Middle School, 95.13% of all students have been fully vaccinated.
Government to approve lifting of almost all Covid-19 restrictions today
Faysal Ishak Ahmed: Coroner to examine 2017 death of Manus Island refugee


Even residents living in and around Addenbrooke's Road will be fined for driving the wrong way along a 'rat run'.
Details of how the restrictions on use of the road will be enforced have emerged after the News obtained the order banning unauthorised vehicles from the route.
Hundreds of drivers have been using the hospital road as a shortcut between the M11 and Cambridge but have now been warned they risk being slapped with a £50 fine, as the News exclusively revealed.
The road, originally built to access Addenbrooke's Hospital and the Biomedical Campus, is now being used by an estimated 400-650 cars a day as a shortcut.
Automatic Number Plate Recognition (ANPR) cameras will actively snare drivers from May 22 drivers.
But residents living on Addenbrooke's Road will also be fined for driving on it unless they are heading away from the hospital.
A biomedical campus spokesman said: "The enforcement is in place 24 hours, seven days a week regardless of direction of travel - if the vehicle drives straight through the campus using it as a short cut then it would be liable to enforcement.
"ANPR cameras are situated at the entry and exit points from the Cambridge Biomedical Campus which will record the time it takes for a vehicle to enter and exit the road.
"If this is a relatively short time, then it will highlight the driver is using the road as a short cut to the M11 or to the city centre and not to access the hospital.
"If you are driving onto the campus with the sole purpose of using the site as a shortcut, you could face a fine of £50. If you are driving on to the campus for any other reason – visiting, dropping someone off or picking someone up then there will be sufficient time to do this without being fined.
"To appeal a ticket, the driver would need to show they didn't commit the offence of using a motor vehicle on the roads covered by the order unless covered by one of the exemptions.
"The main one in this case would be that vehicles can be used 'for the conveyance of persons or good or for the provision of services to or from or at any premises within the Addenbrooke's and CBC Campus served by or situated in or adjacent to the specified roads or parts of roads'.
"So if you are driving on to the campus to drop someone off or pick someone up then you will not be fined.
"If you are dropping off/picking up a relative, staff member or patient or visiting a building on the campus there will be sufficient time for you to do this without receiving a fine and therefore there would be no need to be on a list of permitted vehicles.


text:
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     */
    protected $manager;

    function __construct(ModelManagerInterface $modelManager)
    {
        $this->manager = $modelManager;
    }

    public function transform($value)
    {
        if (null === $value) {
            return null;
        }

        if (!($value instanceof Collection)) {
            throw new UnexpectedTypeException($value, 'Doctrine\Common\Collections\Collection');
        }

        return implode(',', $value->toArray());
    }

    public function reverseTransform($value)
    {
        if (null === $value || '' === $value) {
            return null;
        }

        if (!is_string($value)) {
            throw new UnexpectedTypeException($value, 'string');
        }

        $values = explode(',', $value);
        $tags = new ArrayCollection();

        foreach ($values as $value) {
            $tags->add($this->manager->add($value));
        }

        return $tags;
    }
}

redpajama_set_name: RedPajamaGithub


A much improved photo of cuffs with wrists (not mine). Taking this photo was the only work I did yesterday, which was a joyous novelty. I sat in the sun, knitted, cuddled the cat, watched tv. Not all at the same time. I really deserved a rest. I finished the residency at Bilston on Saturday with mixed relief and sadness. I have loved being there, working with such nice people and learning and exploring so much. But I will enjoy spending some time at home, and being in my own studio. My list of things to catch up with once the residency was over grows ever longer and as yet, nothing is even in progress from it, but I'm looking forward to the Easter break to have at least a couple of days of painting and sorting out.
I was delighted to be able to send off this giant orange blanket to my friend who has just had her third child, who was born a bit early, but is fine now. The blanket just kept growing, and is probably big enough to wrap all three children, in gorgeous orange sunshine!
The cuffs are great. and look at that blanket – not a stitch out of place!
Yummy! The orange blanket makes me happy just looking at it! I love the cuffs with the toile dress – so perfect for spring.
that is the loveliest looking blanket i think i have ever seen, gorgeous!
The baby thinks the blanket is gorgeous too and her brothers think it is great fun to wrap themselves up in it. One very happy friend!


About Juan G. Ochoa, M.D.
Dr. Ochoa is the director of the neurology residency program at the USA College of Medicine and director of the SouthCEP Comprehensive Epilepsy Center at USA Medical Center. His clinical interests include clinical neurophysiology and epilepsy surgery evaluations, and his current research interests include advance seizure source localization and high frequency brain activity associated with seizures.


text:
Legoland Announces Opening Day
CJ McIntyre
A. Boris
It's finally happening.
It feels like we have been waiting a really long time for the highly anticipated opening of the new Legoland in Goshen, and we are happy to let you know after all of the planning and of course the construction of the 150-acre theme park, the wait is over.
According to the Legoland website, the Legoland New York Resort is set to open up on July 4th, 2020 and to say we are super excited is an understatement. The park will feature so many things Lego including, seven themed lands and over 50 amazing rides. Plus the will offer a bunch of different shows and attractions for families.
With the announcement of opening day, Legoland has also now made tickets and season passes to the park available online and have passes for everyone. You can choose a single day ticket for between $60 and $70.
They are also offering different levels of passes that have different benefits respectively, including the Standard pass for around $120, the Premium pass for around $130 and the Gold pass for around $200.
It is going to be a historic opening in July so be sure to get your tickets soon. Happy building and remember "Everything is Awesome at Legoland!"
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Your home-based business requires a business licence and must follow regulations on the home business fact sheet. There are two types of home-based businesses in Kitimat and unique rules apply to each.
Zoning maps are found on this page.
An HBA business allows a business operator to oversee a trade, business, profession, or other occupation by using their house address as the business address. Business-related communication is limited to mail, phone, or online. Clients, employees, and suppliers are not to visit the site of a HBA business. Goods associated with the business (total area up to 25 square meters) may be stored at the address.
HBA businesses are permitted in all residential (R) and greenbelt (G) zones which allow residential development.
An HO business is limited to display and sale of goods or personnal services produced in the home.
HO businesses are permitted in all residential (R) and greenbelt (G) zones which allow residential development, except for the R1-A and R5-A zones. Those who wish to operate an HO business in the R1-A zone may do so if a Temporary Use Permit (TUP) is granted by Council.


text:
Information Technology / Software
Plant/ Equipment
Waste Management Site Services (FFF)
Request Magazine
Home | Articles | Article
Applied bioenergy: Taking it a step further
Written by: RWW | Published: 20 February 2014
The European Bioenergy Research Institute at Aston University is developing innovative bioenergy technology solutions, such as the Pyroformer, to help meet the UK's energy targets while offering environmental benefits and collaboration opportunities for sectors such as energy from waste. Tim Miller, director of operations, European Bioenergy Research Institute, reports.
The increase in the amount of municipal and industrial waste produced across Europe over the past few years is alarming. According to WRAP, households currently throw away £12bn of edible food away each year - that equated to around seven million tonnes of food in 2009/10. But this accounts for only 50% of the problem; figures also reveal that food, drink and packaging waste in the UK supply chain is about 6.6m tonnes a year and costs £5bn.
At the same time, targets to increase the security of energy supply and reduce greenhouse gas emissions have been set for all EU member states, with the UK committed to achieving a 15% share of renewable energy by 2020. Ambitious reduction targets for the UK's CO2 levels - 35% by 2020 and 80% by 2050 - have also been agreed.
Developing a combined solution to tackle the UK's waste problem and ensure energy security is clearly an enormous challenge.
Achieving these targets will require a near 300% increase in renewable energy production before the end of the decade, with bioenergy set to contribute more than 50% of this required increase.
The bioenergy sector is one of the fastest growing markets, with potential to create new economic growth in Europe's regions.
However, to meet energy demand using existing bioenergy technologies would require a volume of biomass four times the height of London's Big Ben.
So how can we tackle waste and ensure energy security without jeopardising both people and planet?
The good news is that the European Bioenergy Research Institute (EBRI) at Aston University in Birmingham is pioneering tangible solutions and advancing bioenergy research and technologies at a rapid rate.
EBRI research
Aston University has been committed to the research and development of bioenergy solutions since the 1970s and in 2008 EBRI was established as an EU Centre of Excellence in applied bioenergy technology. In October 2013 a purpose-built new state-of-the-art facility was opened on Aston University's Birmingham city centre campus.
EBRI carries out world-class bioenergy research, ranging from fundamental laboratory research and development through to the deployment of innovative technologies, with its team of internationally renowned researchers focused on methods of generating energy from biomass. Examples of research currently taking place include:
Anaerobic digestion: Using different anaerobic bacterial groups and archea to degrade organic molecules into biogas and then converted into heat and power in an engine
Algae cultivation: Exploring the exploitation of microalgae for reduction of waste and bioenergy production. There is a growing interest in algae oil as a source of biofuel, with sources coming from a range of habitats, from marine and freshwater environment to desert sand and from hot springs to snow and ice
Catalysis: Key to meeting the challenges of a bio-based chemicals industry, as over 90% of global chemical output relies upon heterogeneously catalysed processes
Combined heat and power (CHP) engines: Adaption of CHP engines (internal combustion engines) for bioenergy provision
Feedstock investigation: Testing and analysis of feedstocks for fuel production (such as sewage sludge, rice and wheat husks, miscanthus and food production residues)
Gasification: Optimisation of technology and feedstocks to improve the range of materials that can be used in gasification and to improve the economics of gasifier projects
Pyrolysis: Research into slow, intermediate and fast pyrolysis processes has been taking place at Aston for many years. EBRI is a leader in fast and intermediate pyrolysis technology, which as the names suggest, is quick; heating biomass in seconds and turning 75% of the weight of the original feed into liquid, which can be used directly as an energy carrier or for heat and power, or upgraded into transport fuels.
Pyroformer technology
EBRI researchers have developed a Pyroformer (pictured), which uses intermediate pyrolysis to uniquely transform multiple waste and residue sources into cost effective heat and power. An industrial scale demonstration plant was recently opened on the Aston University campus where it provides the heat, electricity and cooling needed to power EBRI's building.
The first of its kind in the UK, this technology is a low carbon, renewable and sustainable energy source. Unlike other bioenergy plants, the Pyroformer has no negative environmental or food security impacts.
It can use multiple waste sources and therefore does not require the destruction of rainforests or the use of agricultural land for the growth of specialist bioenergy crops.
Biochar - one of its by-products - can also be used as a fertiliser to increase crop yields, meaning that the process is carbon negative, as 25% of carbon can be saved.
What can EBRI do for industry?
EBRI is keen to deepen links with academia, industry and government, both in the UK and worldwide, to provide business solutions, explore the benefits of bioenergy and make sure that its research has practical applications. In addition, it is looking to develop strategic partnerships with major research centres and companies around the world, to widen its impact and reach.
EBRI has six bioenergy laboratories which are available for feedstock, power and equipment testing. Research equipment includes photo bioreactors harnessing algae, thermal reactors, bench and laboratory scale pyrolysers, gasifiers, combustors, catalytic refiners for biorefinery and the synthesis of fuels and fluidised bed reformers.
The development of bioenergy technology is a priority particularly for the West Midlands, where EBRI is based, as geographical constraints limit the region's potential to generate renewable energy from alternative technologies such as wind, marine and tidal power.
To address this EBRI has secured funding from the European Regional Development Fund to provide a focal point for regional business support and technology transfer and growth opportunities.
This ERDF funding is enabling EBRI to give free support to organisations in the West Midlands to help them understand the market opportunity and develop innovative bioenergy solutions for their business.
EBRI is also working to create a much needed bioenergy supply chain in the region.
Sourcing waste for biomass from within the UK to run bioenergy technologies without having to transport it long distances is crucial for the future. EBRI is looking for West Midlands businesses which produce waste such as food and agricultural waste, sewage sludge, manure and biomass to give them their waste for testing.
What more is needed to bring bioenergy into the mainstream? EBRI researchers are developing new technologies that offer significant energy efficiency and profit gains, but further support is now needed to make this innovative work a viable and sustainable energy source, reduce the world's reliance on fossil fuels and provide an effective waste management solution.
The case for more government investment and policy support for new technologies such as the Pyroformer is strong.
Bioenergy offers significant business, as well as environmental benefits.
In 2009 the government estimated that the global market for low carbon goods and services was worth around £3 trillion a year and could be worth £4.5 trillion by 2015.
Through multiple collaborations, EBRI hopes to build an awareness of bioenergy solutions as alternatives to large scale industrial bioenergy involving the destruction of trees and as a solution to pressing waste and energy needs.
EBRI is proving that real-life solutions for tackling biomass-based waste and residues can be achieved, with both environmental and financial benefits for households, businesses and local authorities, as well as opportunities for wider industry collaboration.
- To find out more about collaboration, testing and business support opportunities with EBRI, contact bioenergy@aston.ac.uk or visit www.bioenergy-midlands.org
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Nov 18, 2014 · Entering the party bus... Follow me on twitter for more https://twitter.com/anevi123.
Nov 17, 2014 · Bey and Jay, 30 seconds in lol Follow me on twitter for more https://twitter.com/anevi123.
After a rocky year, this family showed a united front at little sis Solange's wedding.
Reports of Jay-Z and Beyonce's PDA at Solange's wedding comes just weeks after the pair were caught allegedly arguing on video while attending a Brooklyn Nets game.
May 13, 2014 · It also appears as though the sisters attended Kelly's wedding without Jay Z, who was not included in any of the immigration reports, E! reports.
Nov 17, 2014 · ... including Beyonce and Jay Z. ... January 14 ... Beyonce & Jay Z Arrive for Solange Knowles' Wedding to Alan ... Solange Knowles Got Married!
Beyonce & Jay-Z are ADORABLE as she fixes his bracelet at basketball game!
Solange Knowles and Alan Ferguson Have The Coolest Wedding Ever!
Beyonce & Jay-Z attend Solange's Wedding in New Orleans!


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Q: How can I Use from a variable instead of an amount for nu parameter in nu-SVM for libSVM in Matlab? As you know, libSVM command is like this:
model_nu = svmtrain(train_classset, train_dataset,'-s 1 -t 0 -n 0.5'  );

and when I run it, it's OK.
But I need to use a variable instead of a number for nu. like this:
nu = 0.5;
 model_nu = svmtrain(train_classset, train_dataset,'-s 1 -t 0 -n nu'  );

When I do this, svmtrain function doesn't work.
So how can I use a variable instead of a number in svmtrain function of libSVM toolbox in Matlab?

A: You have to convert the number into char:
model_nu = svmtrain(train_classset, train_dataset,sprintf('-s 1 -t 0 -n %f',nu))

redpajama_set_name: RedPajamaStackExchange


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Find wholesale properties from real estate wholesalers.Look at online bulletins and newspapers for distressed sellers.Post bandit signs in areas where buying a rental property is ideal.Use post-it Notes, direct mail, and postcards in dense income property investment areas.Realtors who know investing can be a good resource and provide potential deals through the MLS (Multiple Listing Service).Focusing marketing efforts in nearby areas (farming) can make buying a rental property easier if you plan on doing the management yourself when being a landlord.
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I wrote this earlier in the year before Captain America: Civil War was released but never got round to posting, so with the recent release of the home video version it seemed like a good time to post it.
Whilst at the Geek Gathering in Llanelli a few weeks back me and Pete were talking about Captain America: Civil War, Pete mentioned that coming from a comic book reading house his daughters were frustrated that all their friends are Team Iron Man. I found this interesting but didn't think too much more about it, that was until earlier in the week when I was invited to the cinema with some of the guy's I work with to watch Captain America: Civil War. This invitation got me thinking about it again, and I asked out of curiosity if they were Team Cap or Team Iron Man, and all of them were Team Iron Man. This is where I got a bit more interesting as I am firmly Team Cap because of the comics I read; so I decided to conduct a quick poll amongst my friends and found that this trend for the most part continued with comic book fans saying that they were Team Cap and the Marvel Cinematic Universe (MCU) fans siding with Team Iron Man (there were a few exceptions either way).
WARNING FROM THIS POINT ON I WILL BE GOING INTO DETAILS OF EVENTS THAT HAPPEN IN THE CIVIL WAR COMIC BOOK SO THERE IS SOME POTENTIAL FOR SPOILERS IF YOU HAVEN'T READ IT!
The big marketing ploy for Civil War asked the question "Whose side are you on?" and from the outset there were claims that it was an impartial look at the question and readers could decide who was more right. I will admit that I do have a bias towards Team Cap as I used this series as part of my dissertation and felt that the depiction of the anti-registration team and their actions in the name of freedom were more justified. However, knowing this bias existed I decided to revisit the series for the first time in a few years and note what I considered to be questionable actions by both sides, and found some interesting points that I hadn't considered before.
For me this highlights how calculated every action that Tony Stark takes is; whilst the death might have been a mistake, the fact that he kept Thor's hair -for years- just incase shows the type of guy Tony is. If these types of actions were driving Tony from the start did he give the mansion to the Avengers for the sole purpose of experimenting on them? He also uses his influence to manipulate Peter Parker into revealing his identity to the world to further legitimise his cause; yet when Parker objects to the extrajudicial imprisonment of anti registration heroes, Iron Man attacks him, uses his Iron-Spider suit against him, and even sets a group of villains on him all despite Parker being a registered and legal superhero at this point. The extrajudicial imprisonment also highlights the extent that Iron Man is prepared to go despite the ramifications, as his forces employ the use of a prison in another dimension. The prison dubbed 42 is situated in the Negative Zone and it is used to hold any Super Human Registration Act (SHRA) violators, without any legal proceedings and whilst imprisoning heroes the pro registration forces were bolstered by villains including killers such as Bullseye, Venom (Mac Gargan), and Lady Deathstrike.
With the opposing side of the conflict it is a lot harder to find these types of faults, outside of they were breaking the law by not complying with the SHRA, but even this seems quite petty as some of the most prominent members such as Captain America and Luke Cage don't have secret identities and were still fighting for the right to privacy. I wanted to keep as impartial as possible and judge both sides as evenly as possible, as a result of this I think I ended up judging Team Cap more harshly and most of my list seemed petty in comparison to the Team Iron Man list. There are a few standout points though, the first is that Captain America throws the first punch in the conflict that ends in the death of Bill Foster. However, leading up to Iron Man claiming that he only wants to talk, the anti registration forces have been drawn into a trap, their teleporters are taken out and they are surrounded by the opposition. This leaves Cap with very limited options and although he could have tried to talk to Iron Man, but (apart from making the comic boring) Cap chooses to fight. The only other major incident is when the Punisher guns down two villains who are trying to join the anti-registration forces. Whilst this act results in two deaths at the hands of a member of Cap's team Captain America doesn't condone the actions and beats up the Punisher and expels him from the team.
All the other things I picked up for questionable acts by Cap were actions like throwing a 'capekiller' from a moving van whilst rescuing the Young Avenger, or taking advantage of Sue Storm's relationship with Namor in an attempt to recruit him and Atlantis to the anti-registration cause. These actions are questionable but in comparison to Iron Man using nanites to enlist an army of villains, or his attempt to blackmail the X-men into joining the pro registration side they still come across as a lesser evil.
So whilst I did pick up on a few examples of transgressions by Team Cap I still firmly believe that the anti-registration argument is stronger. Even though Team Cap are the outlaws of the story they act more like heroes in their actions than Team Iron Man despite them having the law on their side. Therefore I am still firmly Team Cap, but "Whose Side Are You On?"


The Women's Draw – Not Again Dinara!
After watching the Australian Open, the French Open and Wimbledon, tennis enthusiasts must be asking how can it be! Dinara Safina seeded atop the U.S. Open? Remarkable! Tournament directors, wake up! Dinara just does not cut it as a number one seed. If you know New York, you know these fans will announce and perhaps even celebrate her shortcomings in no time at all. After all, they do not call it the Bronx Cheer for no reason.
To make matters worse, professional crybaby Jelena Jankovic is seeded fifth. Granted she helped to launch American Melanie Oudin to stardom and we all appreciate that but how that qualifies the year's most disappointing player as a fifth seed is beyond intelligence. Watch for theatrical injury timeouts and other Jankovic stall tactics as her most sincere effort to stay center stage.
If Dinara or Jelena pull their crybaby antics in New York, they are in for a surprise. These crowds expect champions to perform, not act. Safina and Jankovic at the top of the Women's draw give the whole tournament a suspicious look. The sooner they are gone, they self-destruct, the better the event will be.
The way this draw is orchestrated, the one seed should meet the five seed in the quarters. Good luck. Not going to happen. Jankovic can stumble anywhere along a relatively easy path and Safina can beat herself against any player in the world.
Fortunately, there is a working girl in that top bracket. This may be Ana Ivanovic's best opportunity to make a semifinal this year. The pretty Serb needs a win to get back in the tennis and fashion top 10. She has been working hard on that feeble serve and she just may reap some dividends. Look for Ana to survive in a war of attrition and reach the semis after knocking off Jankovic in the fourth round and Safina in the quarters.
In the bottom of the upper bracket, the tournament's eventual winner resides. Her name is Elena Dementieva. She was one step, one serve away from winning Wimbledon. Elena is one of the few players that can stay with the two seed and the world's best female player, Serena Williams.
Elena possesses the foot speed and the athleticism to reach the finals. Her bracket offers very stiff competition. In the second round, she will most likely meet crowd favorite and Wimbledon quarterfinalist, 17-year old Melanie Oudin. In the second round! Now, that is a tough draw!
Fellow Russian Maria Sharapova should, be waiting in the third round. Wow! The tournament brain trust did not make this bracket easy! In the bottom of the bracket Russian Svetlana Kuznetsova, a finalist in Paris, and tenacious Agnes Szavay look anxious for a shot at Elena. Yikes! There is more talent in this bracket than anywhere else in the tournament.
Listen up Dinara! The world's best female tennis player is positioned at the bottom of the draw. American Serena Williams who stormed past Safina in Melbourne and breezed through Wimbledon may be seeded second but she has the crowd and the surface in her favor along with more game than anyone in the field. She will have an interesting final match with Elena and women's tennis could sure benefit from a memorable finals. We still expect Elena's tough bracket and easy semifinal pairing to play in her favor and carry her to victory.
Serena will have to overcome the likes of always-tough Aussie Samantha Stosur, Daniela Hantuchoya and the ferocious Russian Vera Zvonareva to reach the semis. Serena will ride her loyal and boisterous fans to victory.
Serena's little but older sister Venus is seeded third. She has a tough path to the semis and a rematch of the Wimbledon finals. Kala Kanepi, Anabel Garrigues Medina and Marion Bartoli are waiting in the wings. However, the real threat will come from 8th seed, Victoria Azarenka. If the hard-hitting Azarenka has improved her speed and conditioning just a bit, she should eek out a win over Venus and square away with Serena in the semis. Serena will win, but this one will be tough and a lot more difficult than Elena's semifinal pairing against Safina.
Elena we are counting on you. The door is open. Walk on through and claim your rightful spot. Hail to Elena Dementieva, the 2009 U.S. Open Women's Champion to be!
Dinara Safina is top seeded in 2009 US Open which is certainly going to create a sensation in the NY crowd.
great tips on tennis. I Look forward to reviewing more here in the near future.


Are you sitting comfortably? Then I'll begin. This month, I would like to see some short tales purely for the Love of the Craft... Howard Phillip Lovecraft, to be precise!
I may have an idea for one. Not sure if I can boil it down to fit the word limit.
HeeHee...Lester, use emoji's... readers are evolving downward to where speech will be grunting and words will be replaced with pictures.
I have two entries already. Looking good so far.
I spent some considerable time last night going through notebooks trying to find the material--an old abandoned novel project--to base this flash attempt on. Finally found it, but I learned something about how much I forget. I also am considering a new project, of transcribing that material, since it no longer exists in an electronic format. That way, I could at least find it again.
Just got mine in, right under the buzzer as usual. I can't wait to see all of the stories. Lovecraft is one of my favorite.


We believe effective, high quality teachers are the key to happy, high-achieving students. This core belief informs every decision we make and shapes every aspect of our organization.
We are committed to ensuring all students receive the customized approach and personal attention they need to learn. In place of a scripted instructional model, our exceptional teachers provide dynamic, creative, and highly effective instruction targeted to the needs of the students in their class. To allow for more differentiated small group instruction and structured classroom management, we pair each classroom teacher with a high caliber instructional assistant currently enrolled in a master's degree program. Our Academic Intervention Services provide targeted instruction to address the needs of individual students who may be struggling with certain skills. Through the Children's Institute's Primary Project program, we use expressive play to reduce social, emotional, and school adjustment difficulties and enhance learning skills for our youngest students in need (K-1).
We invest heavily in hiring, training, and cultivating exceptional classroom teachers, in ways that simultaneously further their individual development, advance our larger institutional goals, and ultimately drive student performance. We build extensive professional development for teachers into the school calendar to help them continually improve their skills. We employ a staff of in-house content area specialists with deep experience and expertise in literacy, writing, and math. They provide daily one-on-one support, resources, and training, including classroom modeling, observation, and feedback. MCS also brings in academic consultants and sends teachers for specialized training and experiences to help our teachers hone their craft.


I have signed an Employment Agreement for a sum of Rs. 50,000/- towards training cost, if I left the company before the six months, and that too with serving a notice perid of 30 days. But, the current position is, that I have resigned after a service of 3 months, by serving a notice period of 7 days due to unavoidable circumstances concerning my health issues. And the same was approved and accepted by the HR department of the company. Now, the company has sent me a notice for the recovery of Rs.26000/-, calculated on prorata basis, for leaving the service before 6 months.
1- Is it valid as per the law?
2- Am I liable to pay the amount, so claimed?
3- Could I have been prosecuted on the terms of such an adverse agreement?
has done on training etc.
ofcourse it is not valid in law but your piece of mind can be distrubed by filing a case if they do so.
IP Agreement at Exit - How valid is this for a company to ask?
Notice Period - not agreeing to buyout - legal options?


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'I told Chantelle I slept with men just after she had Dolly... and she still wanted to marry me': Alex Reid confesses he 'has tried everything - even prostitutes'
By Louise Saunders
Published: 02:00 EDT, 20 November 2012 | Updated: 10:17 EDT, 20 November 2012
He's been accused of turning their home into a 'sex dungeon' and arranging to meet up with a man for sex while dressed as his female alter-ego, Roxanne.
But Alex Reid has now hit back at Chantelle Houghton's explosive claims, admitting while he has slept with both men and prostitutes in the past, he never cheated on his former fiancee.
The 37-year-old cage fighter explained despite Chantelle - the mother of his five-month-old daughter Dolly - knowing all about his 'weird and wonderful' past, she still wanted to marry him.
'Sexually liberated': Alex Reid has admitted to sleeping with both men and prostitutes in the past
In a revealing interview with Now magazine, Alex said: 'Chantelle knew everything before we got together. Was she the only person in this country who didn't know I was a cross-dresser?
'In my opinion she knew all about me, so what she's been saying makes no sense to me. In my younger years I did experiment with men.
'Speaking to her has been a real comfort': Chantelle... 'I've seen more than you can imagine': Katie Price opens up...
'What happened to our quarter of a million pound baby?':...
'After we had Dolly I sat down and made it clear that I'd slept with men back in the day. But she still wanted to marry me.'
Explaining he has now become the victim of vile homophobic abuse thanks to Chantelle's shocking Twitter rant, Alex admitted despite his past experiences with men, he prefers sex with women and is still looking for the perfect woman to spend the rest of his life with.
In happier times: Alex claims his former fiancee Chantelle Houghton knew all about his 'weird and wonderful' past
But the revelations about the star's chequered sexual past didn't end there, with the father-of-one confessing to sleeping with prostitutes before he met Chantelle and ex-wife Katie Price.
He added: 'I've slept with prostitutes but that was a long time ago. A lot of men have done that. I've had a varied, fun past. I enjoyed a lot of different things.'
Alex also refuted Chantelle's claims that he had turned their Essex home into a sordid 'sex dungeon', explaining what the 29-year-old star was referring to was 'a couple of sex toys and some porn'.
Despite his 'sexually liberated' past, Alex hit back at his ex's claims that he had cheated on her when Dolly was first born, explaining the text messages she found on his mobile phone about him meeting up with a man with a 'bag of sex toys' was 'a joke'.
Roxanne: Alex said the only time he discussed dressing up as his female alter-ego with other men was a spot of 'building site humour'
And the star revealed that Chantelle knew all about his penchant for dressing up as a woman, claiming the only time he discussed Roxanne with other men was when he was indulging in a spot of 'building site humour'.
However, a representative for Chantelle has hit back at Alex's claims, explaining the cage fighter had told her Roxanne was just a publicity stunt.
Read the full interview in this week's Now magazine, out now
The spokesperson told Now magazine: 'Alex told Chantelle Roxanne was just a publicity stunt, so she was shocked when she walked in on him dressed up while she was eight months pregnant.
'She was so upset that she slept on a floor for four days. After she gave birth, she found a text from a man, then Alex confessed to having had sexual experiences with men. She knew things couldn't work as he'd lied to her from the start and wasn't the man he claimed to be.'
Alex's revealing interview comes after Chantelle recently let rip on her Twitter page, alleging that Alex had been planning to sleep with another man while dressed as Roxanne.
She wrote: 'Ok had enough, I'm putting the record straight. I've been in f***ing bad place for weeks now but reason for that is this: I found text messages on Alex's phone when she was 6 weeks old, it was to a man and he was arranging to meet up with him as Roxanne for sex.
'It wasn't the first time either. So yeah I'm in hell right now but who wouldn't be.
'Oh and yes when I was 8 months pregnant Alex turned my house into a sex dungeon and I slept on my flat floor for days...Cos I couldn't come home. (sic)'
Read the full interview with Alex Reid in this week's Now magazine, out now.
Alex Reid confesses to sleeping with men AND prostitutes but claims he didn't cheat on Chantelle Houghton


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The Nando Floor Lamp is a simple, elegant fixture with a brushed nickel metal body and a unique tansparent PVC second outer shade. This contemporary floor lamp also features an inner shade made of white fabric and dual on-off pull chains. It requires two 13W fluorescent CFL type bulbs (included), has a color temperature of 2700K and an E-27 socket. The Nando Floor Lamp has a refined style that is centered around clean geometry and interesting materials. It will look great in almost any contemporary or modern style interior setting.


text:
Q: how get access to a password posted with a form? I have a form that displays a password field and when the form is posted I call a javascript function during the page's onload -- and when I retrieve the password field it never has the password I entered, it's empty. Is calling a javascript function from onload the wrong approach here if I'm trying access the contents of the posted form?
<!DOCTYPE html>

    <meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
    <title>Beta:</title>

    <form method="post"  action="index.php">
    Beta: <input id="theUsersPassword" name="usersPassword" type="password">

    <input type="submit" value="Submit" />
    </form>

A: I guess you don't want to check the input onload, you want to check it when the form submits right? Because at onload the user hasn't had the chance to enter anything yet.
If you want to do it onsubmit, just change your form tag to this:
<form method="post" action="index.php" onsubmit="checkPwd()">

A: That's because the element doesn't exist anymore.
Javascript only runs on one page, so if you do
document.getElementById('passwordform');

it won't find it because there is no element with that ID.
You could do it in javascript by storing the password in a cookie, or retrieving it via the LocalStorage api, but I'm not even going to show you how to do that, because it's unsafe.
Javascript is a client side language, so any code you write in it, is sent to the browser. This means that every user can view and manipulate your code.
You should do it with a server side language such as PHP.
In php, you can simply compare the value to the pasword you expect.
There are 2 ways to sent data from a form to the server: using the POST method, or using the GET method. The Get method is used for sending shorer pieces of information, and are appended to the url in the form of
example.com?variable=value

This is not a good idea for information that needs to be secure, and since a url has a maximum length (different for different browsers), so when you send password information, you should use the POST method.
So, your login form could look like this
<form action='securedpage.php'>
    enter your password: <input type='password' name='pass'>
    <input type='submit'>
</form>

Now, in  securedpage.php, you could do something like this:
<?php
$expected_pass="!4mr00t";
if($_POST['pass']===$expected_pass){
    //show your content
}els{
   //show homepage
}
?>

A: I could be wrong but isn't this normally done with PHP?
<?php
  if (isset($_POST['variable'])) {
   $first = $_POST['variable'];
   echo $first;
  }
?>

<form action="" method="POST">
   <input type="password" name="variable" />
   <input type="submit" />
</form>

This code would spit out a password entered into a form.

A: You cannot access the POST data fields from JavaScript.
What you do is that you block the real form submission and get the data from the form.
form.onsubmit = function () { checkPwd(); return false; };

Or if you're trying to do some kind of a validation, you need to return a boolean value from checkPwd and do form.onsubmit = checkPwd

A: Try this:
<form method="post" action="index.php" onsubmit="return checkPwd()">

checkPwd() must return false to avoid the submission (If any problem) o true to perfom the action (If everythings is correct).


Lorraine Taogaga (aka Whaea Lorraine) is the Kaiārahi of the Te Ao Māori Course, in which she will also lecture, in 2018. Having taught the Te Reo Māori Beginner's Course at Carey in 2017, she will continue in this role for 2018 also.
Lorraine is completing her Master of Theology at Laidlaw College and has trained as both a lawyer and Te Reo Māori teacher.
She has two children, one recently ran a political campaign and the other married. For the first time, this year, she became a grandmother to Willow.
Lorraine attended Pt Chevalier Baptist Church for ten years and now attends the Equipper's Church in Central Auckland.
…Ko te manu e kai ana i Te Rongopai, nōna te oranga.
…The person who partakes of the Gospel will have everlasting life.


text:
Going for Gold
Nie-fiksie / Non-fiction: Business / Besigheid
Zoltan Erdey
Nie-fiksie / Non-fiction - Business / Besigheid
Do you want to build your wealth and secure your financial future? Do you want to ensure that inflation does not eat away at everything that you have worked so hard for? Do you want to own wealth outside of the paper financial system? If your answer to these three
questions is yes, then you need to own real money. Not rands, dollars or euros. These are merely fiat currencies. You want to own gold and silver, as without them, your wealth is only worth the value of the ink and the paper on which it is printed.
For thousands of years, holders of gold and silver have discovered that both metals are monetary antidotes against global financial chaos caused by debt, fiscal imprudence and ad infinitum money-printing. The proprietor of even a few ounces of gold is not only an
investor, but an individual with the assurance that their wealth and purchasing power remains preserved.
This book is not an attempt to coerce investors into allocating a portion of their total investment portfolio to precious metals. Rather, it is concerned with speaking directly to the South African investor and decluttering and contextualising the vast amounts of information
available about precious metals. This book also provides counsel that the mainstream financial industry has disregarded at best, and suppressed at worst.
New Media in the Information Society
Z. Lesame, B. Mbatha, S. Sindane
Since their emergence around 1985, the new media have significantly changed the way in which we, the consumers, view and interact with our everyday world. Developed countries already have access to advanced new media applications, while developing countries are continually making innovations and increasing their presence in the new media sector. New media in the information society discusses social, economic, educational, political and regulatory aspects of the new media, as well as their impact on society and users in general. New media in the information society guides the student through the world of new media - from earliest history to modern-day theories and applications. Large-scale issues such as e-government, cybercrime and Internet policy are explored, although the focus remains on the impact of new media on the individual. Revision questions are provided for each chapter. Contents include the following: Social networking; virtual worlds; new media and journalism: offline and online newspapers and magazines; mobile telecommunications, promotion and distribution; globalisation and the public broadcaster; information and communication technology infrastructure in South Africa and the rest of Africa; internet addiction disorder. New media in the information society is aimed at senior undergraduate students who are studying new media courses or information and communication technology modules, as well as at students of telecommunications policy and regulation. Telecommunications policy researchers and ICT sector analysts will also find this book useful.
Let My People Go Surfing
Yvon Chouinard(Introduction by Naomi Klein)
In this newly revised 10th anniversary edition, Yvon Chouinard--legendary climber, businessman, environmentalist, and founder of Patagonia, Inc.--shares the persistence and courage that have gone into being head of one of the most respected and environmentally responsible companies on earth. From his youth as the son of a French Canadian handyman to the thrilling, ambitious climbing expeditions that inspired his innovative designs for the sport's equipment, Let My People Go Surfing is the story of a man who brought doing good and having grand adventures into the heart of his business life-a book that will deeply affect entrepreneurs and outdoor enthusiasts alike. 'This is the story of an attempt to do more than change a single corporation--it is an attempt to challenge the culture of consumption tat is at the hear of the global ecological crisis.' --From the Foreword by Naomi Klein, bestselling author of This Changes Everything
Listen Like You Mean It
Ximena Vengoechea
Hear me out. Does this sound like you? You end a team meeting and can't recall a single thing that was said. You leave a conversation with a friend feeling disconnected and unfulfilled. You think you and your boss are on the same page, only to find out you haven't been meeting expectations. Fortunately, listening, like any communication skill, can be improved, and Ximena Vengoechea can show you how. As a user researcher, she has spent nearly a decade facilitating hundreds of conversations at LinkedIn, Twitter and Pinterest. It's her job to uncover the truth behind how people use, and really think about, her company's products. In Listen Like You Mean It, she reveals the tips and tricks of the trade, including:
- How to quickly build rapport with strangers
- Which questions help people unlock what they need to say
- When it's time to throw out the script entirely
- How to recover from listener's drain
How To Succeed in the African Market
Winfred Oppong-Amoako
Home to some of the world's fastest-growing economies, Africa is a hot investment destination. More than 75 per cent of companies and investors in Africa are successful. Why? And how could you reap the benefits of doing business on the continent? In this book, business adviser, executive coach and author Winfred Oppong-Amoako presents a detailed picture of Africa's investment environment, outlining the risks, challenges, misconceptions and opportunities, and providing a step-by-step guide for approaching the African market.
The book covers key topics such as informal trading, China's investment in the continent and the impact of recession on long-term GDP growth, and lays out certain factors that need to be taken into consideration before investing, including cross-border trading, corruption, permits and legal contracts.
If you're new to investment or a successful businessperson looking to expand your brand, How to Succeed in the African Market is an indispensable reference, giving you the information that will enable you to make informed decisions and prosper.
The Economics of Water - Water for life; Sanitation for Dignity
Willem N. Meyer
A coherent survey and explanation of many crucial issues relating to the supply and demand of water in South Africa. Includes economic mechanisms and their impact on production, distribution and socio-economic integration.
Contents include the following:
Basic needs approach to development thinking
Hydrologic cycles I and II
Water availability and demand in South Africa
Water supply and demand management
Water market and government intervention
Welfare economic considerations
Water pricing, practice and problems
Jerks at Work TPB
West, Tessa
The Five-Minute MBA
Wayne Brown
Who needs to study for an MBA when you have this book? The Five-Minute MBA is a deceptively simple little book that presents wise business advice in a clear and concise way.
Written by New Zealand's top 'corporate doctor', Wayne Brown, it teaches ten crucial lessons vital for everyone at every level of business.
By distilling the MBA into under 100 pages, Brown has ensured that only the most important and necessary bits remain, those that will lead to dramatic improvements in any business.
From treating customers correctly and fixing mistakes upfront to doing the right thing and remaining accountable, The Five-Minute MBA is a practical, experience-based MBA crashcourse that is guaranteed to offer genuine value, whether you are a junior, mid-level or senior businessperson.
Now you, too, can learn how to bring everyday good health to your business.
Accountable - How we can save Capitalism
Warren Valmanis, Michael O'Leary
'Uses a combination of great stories and thoughtful analysis to suggest that we must find a way to change the purpose of our corporations if we are to build a society that works for all of us.' Rebecca M. Henderson, John & Natty McArthur University Professor at Harvard University
'Fresh, balanced, highly readable and deeply informed' John Pepper, former Chairman and CEO of P&G
'Thought-provoking and insightful, Accountable offers a pragmatic and original roadmap to transform capitalism into a system that's more inclusive, sustainable, and just.' Dr. Rajiv J. Shah, President of The Rockefeller Foundation
Capitalism is failing and the tools we are relying on to fix it - corporate social responsibility, divestment, impact investing, and government control - are only making things worse.
-Chevron boasts about the $50 million per year it spends on renewable energy whilst it spends 200 times that on oil exploration
-Goldman Sachs touts its 10,000 Women initiative but its board ranks 358th out of the Fortune 500 for gender diversity and women earn 55% less than men do on average.
By focusing on corporations rather than people, we've put our faith in empty trends and brand-focused window-dressing. Why should those responsible for our current crisis be trusted to fix it? In Accountable, authors Michael O'Leary and Warren Valdmanis offer a blueprint for everyone to take responsibility for using their economic power as consumers, as investors, as employees, and as voters to trigger a fundamental shift away from an economy that is unethical, unfair, and destructive to our environment and institutions. Their investigation cuts through the tired dogma of current economic thinking to reveal a hopeful truth: if we can make our corporations accountable to a deeper purpose, we can make capitalism both prosperous and good. Trenchant and gripping, this is an indispensable guide and call to action for citizens to take control of our economic power and hold corporations to a higher standard.
Global Investing Made Easy
Warren Ingram
Investing overseas can be a very intimidating, even scary, subject. Even though many of us would love to invest internationally, we have limited information on how and where to place our money. This book will demystify global investing by providing novice investors with practical guidelines on how to invest overseas while helping them to avoid the inherent pitfalls.
Global Investing Made Easy covers all the main aspects that a non-financial person should know before embarking on a global investment journey and will be helpful to investors across the globe. People of all ages and levels of wealth will benefit from the practical, easy-to-understand, jargon-free information required to invest in the international markets, proving that financial freedom is possible for everyone.
Become Your Own Financial Advisor
Your step-by-step guide to financial peace of mind! How can you become financially secure with the resources at your disposal? What is the safest way to invest and accumulate money? And why is it never too late to start planning your financial well-being? In this new, updated edition of the bestselling Become Your Own Financial Advisor, all of this, and much, much more, is explained.
Money plays a role in nearly every aspect of our lives, and yet very few of us know how to save, where to invest and how to avoid money troubles. This highly accessible book is aimed at anyone who wants to improve their financial situation, from the financial novice who needs clear basic guidelines on how to deal with money, to those who are more financially savvy but want to supplement their knowledge.
Covering a range of topics, from saving, investing, debt management and buying a house to blunders to avoid, Become Your Own Financial Advisor provides people of all ages and levels of wealth with practical information on how to improve their finances. In the process, it shows that financial freedom is possible for everyone. This, the second edition of Become Your Own Financial Advisor, has been updated with new types of investments, fresh approaches to technology, the latest tax information and further feedback on 'Julia', the savings rock star.
Wandile Sihlobo
'My hope is that people can grow to appreciate this sector - its challenges and opportunities, but most importantly, the role agriculture can play in improving South Africa's rural economy, creating jobs and bringing about much-needed transformation (or inclusive growth).'
Wandile Sihlobo is perfectly positioned to provide a well-rounded, accessible view of agriculture in South Africa. He spent his school holidays in the rural Eastern Cape, studied agricultural economics at university, has worked in private-sector agriculture, consulting with farmers across the country, and has been an adviser to government as part of South African policymaking bodies.
Finding Common Ground is a selection of key articles from Sihlobo's regular Business Day column, framed with insightful commentary and context. The book covers the broad themes that have marked current discussions and outlines the challenges and opportunities faced by South Africa's agricultural sector, including:
The contentious and complex issue of land reform;
The potential for new leadership to revive the sector;
How agriculture can drive development and job creation;
Cannabis as an exportable commodity;
The urgent need for agricultural policy to address gender equity and youth involvement;
Technological developments and megatrends that are underpinning agricultural development;
The importance of trade in growing South Africa's agriculture; and Key lessons that South Africa and other African countries can learn from one another.
Ultimately, Sihlobo is optimistic about the future of South Africa's agricultural sector and shows us all - from policymakers to the general public - how much common ground we truly have.
Vusi
Vusi Thembekwayo
Maverick. Leadership genius. Self-made millionaire. The rock star of public speaking. Vusi Thembekwayo has been called many things. Join him in his journey from township to the top echelons of SA business, to becoming one of youngest directors of a listed company and CEO of an investment firm. As a Dragons' Den judge and a sought-after public speaker across the globe, Vusi doesn't just talk business - he lives it. Now you can learn the secret of his success and how to shape your own destiny.
A Guide to Passing General Management
Vrba MJ, Brevis T
A guide to passing General Management provides students of management with a theoretical framework of the principles of general management. It can be used as a workbook to supplement most of the current textbooks on general management as it provides a condensed overview of the most important aspects of contemporary management theory. The guide is organised around the four fundamental management functions carried out by managers at all levels of the organisation, namely: planning, organising, leading and control.
In addition, topics on the evolution of management theory, the business environment, globalisation, managerial decision making, information management and business ethics are included.
The text is structured in short concise topics, covering the following:
A conceptual overview of each topic
Additional reading resources
Multiple-choice questions and discussion questions to test the student's understanding of each topic
Guidelines to answer the self-evaluation questions
A guide to passing General Management is a must for every stressed student who faces forthcoming tests and the final examination in general management. It is also a handy guide for the practitioner who aims to brush up on the basics of general management.
Vince Cable
A captivating economic history of government all over the world.


text:
Driver injured and trapped in car after crash
A driver was injured and trapped in his car on Sunday after skidding and crashing into a tree in the far north of the country.
Das Fahrzeug wurde bei dem Aufprall komplett zerstört.
The incident happened on a route between the small towns of Emeschbach and Antoniushaff in the afternoon when a driver is reported to have complete lost control of his car on a bend before swerving and smashing into a tree in such a way that it trapped him inside the vehicle.
A Luxembourg Air Rescue helicopter was drafted in and once the injured driver was freed from the wreckage, he was flown to hospital. His condition is not known at this stage.
According to police, it is like that a combination of an oil patch on the road and "inappropriate speed" were the cause of the accident.
During the rescue and clean-up operation, the road was completely blocked to traffic.