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Open casket vs. a Closed Casket funeral- The Fundamental Information to Help You Decide
There are many things to address when dealing with a funeral. Deciding between an open casket or a closed casket is just one of the many. Sometimes, a closed casket is the only option (we're going to come back to that), but most of the time, you need to decide between the two kinds.
For instance, if children will attend the funeral service, seeing someone they really cared about and loved may be incredibly difficult. Therefore, a closed casket will be the better choice. Children and highly emotional people will always find it consuming and difficult to bare the view of the deceased. The sealed casket service is the wiser option in such situations.
What are the fundamental aspects of an open casket funeral?
The term pretty much says it all, and in the open casket funeral, the body of the deceased is shown for viewing.
For completing the open casket funeral, the funeral service must take specific steps:
They take care of the embalming of the body. It's natural for the body to start decomposing quite fast after death. When you're planning for others to see the deceased's body, the embalming cannot be skipped.
The body has to be dressed. In many cultures, it's the family members that ensure the clothing for the deceased. They typically select pieces of clothing that the dead was found when he/she was living. Sometimes, the deceased may have experienced fast weight loss/weight gain just before the death, in which some clothing alteration may be required. There's also the scenario when new clothes have to be bought by relatives.
The funeral home can also use some makeup on the body. One member of the funeral home's team will apply makeup on the shown skin to make it look healthier. He/she can also add some color to the cheeks and lips, helping the body to resemble a life-like look.
The people from the funeral home will also take care of the deceased's hair. More often than not, they will ask for a picture of the deceased to see how he/she used to style the hair.
After the body is prepared, the body of the deceased will be laid in a casket. Typically, only the top half of the casket is going to be open, allowing the people attending the funeral to see it. The head, the shoulders, and the chest of the deceased will be visible.
Not everyone agrees that the open-casket funerals are standard. Many notices that the body is displayed throughout the wake/vigil/visitation, but not throughout the funeral service per se.
Therefore, you can leave the casket open for the moment when people attend the funeral, asking the funeral directors to close it when the service starts. You can also leave it open throughout the funeral service, too- the decision belongs to you!
Some would instead leave the casket open only for the close members of the family to take a last look at the deceased. They simply close the caskets when other people attend the service. Societal norms, personal preferences, and religious traditions will play a role when deciding on which style you use in the end.
How to describe a closed casket funeral in a nutshell?
Just like in the case of an open-casket funeral, the closed casket funeral refers to the body not being shown throughout the funeral service. Therefore, nobody is going to see the body of the deceased. The body was shown, however, throughout the vigil, the wake, or visitation. For specific reasons, though, the casket is closed for the funeral service.
When the body is never shown, it may or may not have been through an embalming process. Embalming is required if the body of the deceased will be displayed at some point throughout the funeral services.
The etiquette on open casket funeral- here's what's to know
In the case of open-casket funeral services, the body will be embalmed, dressed up so that it presents a life-like appearance. It's an overwhelming moment, so you should brace yourself for it.
When you go with an open casket funeral, here are some do's and don'ts to remember:
You should try to stay close to the casket so that the family doesn't get the impression that you're grossed out by the deceased. When you no longer feel comfortable, you should stay away from it and remain seated.
Under no circumstances is allowed to touch the body. For preventing this kind of incident, some caskets feature a glass.
Try your best not to comment on the appearance of the deceased. Keep in mind that the dead cannot look exactly like he/she used to look when alive. Don't make any comments at all.
Give space to family members. It's perfectly understandable why the family members are unable to stay away from the casket. Give them the space they need, while not pushing through the guests.
Viewing the deceased is seldom easy or comfortable, especially if you were close. If you don't know how you're going to react, it's a good idea to ask someone in the family or a friend to stand by you for emotional support. Every mourner has their unique way of paying respects to the dead, and people will understand you when you're incapable of seeing the deceased in the open funeral casket.
Why would you decide on a closed-casket funeral?
No matter if you're planning the funeral for someone in your family or for your own, you should give it a good thought before choosing.
Most of the time, when we think about someone selecting the closed-casket funeral, the state of the body jumps to our mind as the main reason for it. A chemical accident or a body mutilated in a fire do alter the body of the deceased. But it's not a common scenario.
On the contrary, many people wish to have a closed casket funeral for honoring the deceased, no matter the state of the body. There's also the category of people who see the open casket as an invasion of intimacy. It's disrespectful for both the deceased and the family of the dead. Truth be told, it's still a personal thing, and it can cause a lot of disagreement within a family when preparing the funeral. Once more, we notice the importance of pre-need funeral planning, especially within a family that typically argues on everything.
Religion is another aspect that matters when choosing a closed casket funeral. The majority of religions will allow the choice of having the viewing or the wake up to the family members. However, some exceptions don't endorse the open caskets.
For instance, Jewish funerals don't include a viewing, but have the "keriah". It's a ritual where the close family gathers before the service.
The Muslim religion doesn't allow an open casket viewing as well, with bodies being buried right after death.
Last, but not least, the Quaker funeral also has strict rules about the viewing and the wakes, allowing only the closed casket funerals.
Even if the religion isn't your primary reason for which an open casket doesn't interest you, there are plenty of other reasons that count too.
With many people feeling uncomfortable about the embalming process, it's totally understandable why the closed casket funeral becomes the only choice. Even if the funeral home's staff is well trained and experienced, making the deceased to have a life-like appearance (without losing a natural feeling), it's perfectly natural for people to avoid the open-casket funeral.
When you go with a closed casket funeral, you show a lot of consideration to the people attending the funeral service. At the end of the day, people react differently to the looks of dead bodies.
All in all, the wish for a closed casket has more psychological reasons than we'd think. Even if people believe that the open casket helps the mourners to accept death and say their final goodbye to the deceased, studies are proving wrong. A closed casket gives the mourners a sense of finality, easing out the acceptance of death.
More than anything, it doesn't matter why you choose a closed casket funeral. It's far more vital that it respects the last wishes of the deceased.
Open or closed casket funeral? The differences to help you understand
Even if we went over the details on each type, listing things also seems to help a lot more. Here's our list when comparing the two:
1. Not everyone attending the service is willing in seeing the deceased
There's always the category of people not wishing to see the body of the deceased. Maybe they're uncomfortable with seeing a dead body, or perhaps they just don't want to know the one they used to love as dead.
For no matter the reasons, though, it's better that you give them the possibility of not seeing the body. In most situations, the casket will be the focal point of the funeral service. When mourners are entering from the back, one that doesn't want to see the body can actually stand toward the rear.
2. Some mourners want to see the body of the deceased
Even if we don't deal with death until later in our life (hopefully), many of us know for sure about the practice of seeing bodies after death. For many religions and cultures, the method seems quite weird. After all, there's nothing natural about applying makeup on a dead body, for making it look "alive."
However, it's not easy for people to see someone they've cared about like a dead person. They need closure, and taking one last look at the body gives them closure.
Should you decide to go with a closed casket funeral, some of the mourners will end up frustrated and upset for not being able to see the deceased one last time. Even it's not appropriate, and some may want to kiss the hand of the deceased or simply touch it.
3. It's difficult to choose between the two
When the appearance of the deceased has been dramatically changed before dying, choosing between the two is more complicated. Chemotherapy leaves deep marks on people, and the loss of hair is really heavy for the family. Sometimes, the staff members of the funeral home can do their best to make the deceased look life-like. Despite their efforts, some dead don't look like they used to at all.
Therefore, it\s better to honor and respect the deceased and have a closed casket funeral instead.
4. At times, the closed casket funeral is the only choice
People die too often in traumatic accidents or on the cause of some injuries. If so, the body may not allow a display at the funeral service. A body that was burned or drowned doesn't allow an open casket. It's the same with infants, and the picture of open infant caskets is unbearable. Most of the infant caskets are closed throughout the funeral.
The funeral directors are experienced so they can give you a piece of advice. After all, it's not wise to go with an open casket funeral when the body is decomposing or intensely damaged. It's traumatic for anyone attending the funeral service.
5. The culture can decide the type
Go back to see details on which religion as for a closed casket funeral. However, not all Jews or Muslims go with a closed casket funeral.
The culture, personal values, and the country of origin are also significant when making that call.
6. The closed casket funeral is cheaper than the open casket type
It's emotionally draining to plan a funeral. More often than not, the mourners planning the funeral don't have time to address financial issues as they cannot deal with their emotions. They're willing to pay any amount of money just to get it over with.
With embalming being necessary for open-casket funeral and quite expensive too, it makes sense that the open casket funeral is pricier than the closed casket type. Even though it's unpleasant to think it, sometimes your wallet just doesn't allow an open casket funeral.


The preliminary report of the Donnelly-Wiltshire review of the national curriculum has been released, having been with the Minister since the end of March. (Earlier background.) The final report will be with the Minister (though not necessarily released) at the end of July. As Daniel Hurst notes in the Guardian Australia, there is virtually no hint in the 17 page interim document of what will be in the final version. It is all about process.
scope for choice and flexibility in curriculum delivery without undue encouragement of the adoption of ephemeral or other practices which are not evidence based.
The remarks about balance, bias and selectiveness will be of interest to those historians and teachers who believe that all history is interpretation.


Changes associated with aging skin lead to changes in appearance that cause distress to many women and men, and lead them to seek aesthetic treatment. Fortunately, an increased understanding of the underlying pathophysiologic changes has led to development of aesthetic agents that target underlying mechanisms and injection techniques that result in a natural, balanced, and pleasing appearance.
The aims of this article are to summarize best practices for product selection and injection of hyaluronic acid fillers to optimize aesthetic outcomes and minimize the risk for adverse events. The faculty for the program includes experts in advanced aesthetic techniques. This educational program will review key information about facial and vascular anatomy, selection of the most appropriate hyaluronic acid product based on rheology and physical properties, and advanced injection techniques using both a needle and a blunt-tip cannula.
Adapted from Costa CR, et al. Plast Reconstr Surg. 2016;138:233e; Bogdan Allemann A, et al. Clin Interv Aging. 2008;3(4):629-634; US Food and Drug Administration. Approved Dermal Fillers; Available at: https://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/CosmeticDevices/WrinkleFillers/ucm227749.htm#approved; Bloom M and Palm M. 2018 personal communication.
Choosing the most appropriate cannula for the chosen product and area to be injected must be given careful consideration. Delicate tissues (ie, lips and the tear troughs), require a smaller cannula (eg, a 27-gauge cannula). More robust tissues, such as the midface, melolabial folds, nasolabial folds, and hands, require a larger-gauge cannula (eg, a 25-gauge, 1.5 inch long cannula) in order to accommodate products with higher viscosity and allow for threading through thicker tissues.
Injection techniques and location of injections compared with the vascular and neurovascular anatomy are of paramount importance to minimize adverse events.
When performing microinjections, injection techniques include linear threading, crosshatching, fanning, serial puncture, or even a combination of several of them, depending on expected results, in order to receive an optimal result. [Landau 2015] NOTE: It is very important to watch the videos demonstrating the injection techniques – the best practices for each injection area are summarized below. Although the demonstrations were performed using the non-animal stabilized hyaluronic acid (NASHA) line of products, one can use any FDA-approved product with similar physical properties (Table A).
Cannula injection of the tear trough: The ideal filler has a low level of hyaluronic acid crosslinking. Create an entry port with a 25-gauge sharp needle based on a diagonal line at a point on the anterior cheek. Use a 27-gauge, 1.5-inch cannula. Insert the cannula below the level of the orbicularis oculi muscle, advancing the cannula perpendicular to the tissue.
Cannula injection of the mid-face and cheek: Ideal fillers are a combination of a hyaluronic acid with a high G prime (eg, a large particle hyaluronic acid) and a different product with a good combination of support and flexibility. Create a pilot hole with a 23-gauge sharp needle and use a 25-gauge, 1.5-inch microcannula for the injections, using a lift and tack or layered lifting technique. Inject about 2/3 of the product onto the periosteum of the midface and about 1/3 of each aliquot coming up through the deep fat pads and into the superficial fat pads. Create another pilot hole in the area that was previously injected and use a 25-gauge, 1.5-inch microcannula for the midface volumization, using a radial threading technique to treat the anterior midface.
Cannula injection of the lips: A small particle hyaluronic acid filler with lidocaine is the only FDA-approved product for injection in the lip area with a microcannula. Four important factors to consider are: 1) the definition of the vermillion border; 2) the fullness of the lips; 3) the pout; and 4) the proportion of the top and lower lips. Create a pilot opening at the corner of the mouth with a 25-gauge needle to be used with a 27-gauge, 1.5-inch microcannula. Inject 0.1 to 0.2 mL of filler in each of the four quadrants (pillows) of the lip. Next, angle the cannula into the top lip in the submucosal plane to inject first into the dry red lip, then aim into the mouth at the wet-dry border and even more posterior or lingual to that in order to push or roll the lip out. Repeat this technique for the other side. Use the sharp needle to give more definition to the top lip at the vermilion border in the lateral Cupid's bow. One can complete this area by injecting the marionette area with a 30-gauge needle. Begin with the pillar of the marionette area and inject very slowly using very small quantities of product, working from the jaw line up to the oral commissure.
Microinjection of the forehead: The filler (small particle hyaluronic acid with lidocaine) is mixed with 0.3 to 0.5 cc of 0.5% lidocaine with epinephrine buffered with bicarbonate in a 0.3 cc syringe, and is ideal for the forehead as it provides a thinner product that is more easily molded into thinner tissues. Inject at least 1 cm above the orbital rim because it is a safe place that is super-periosteal on top of bone and below the area where important vessels are located. Inject down to bone on the super-periosteum and march over laterally going very slowly and using small aliquots. Finish laterally, injecting perpendicular to the surface of the skin.
Microinjection of the neck: The filler is mixed with 0.5% lidocaine with epinephrine buffered with bicarbonate for vasoconstrictive effect and to minimize the degree of swelling and bruising. A sharp needle is the only appropriate approach for placing filler in the neckline. Bending the needle allows for a tangential approach while working from the right side of the neck. Inject in an anterograde and retrograde linear threading pattern to subcise and fill the neck lines.
When performing microinjections or blunt cannula injection of hyaluronic acid, prevention and management of adverse events must always be top of mind. Safety techniques include aspiration after insertion to ensure the needle/cannula is not in a vessel and injection of small, precise aliquots at a slow rate. If resistance is encountered and/or the patient experiences pain, the injector should stop and reposition the cannula or needle prior to injecting more filler. [Signorini 2016; Beleznay 2015]. Interaction between the hyaluronic acid fillers and the tissues may cause immune-mediated and delayed-type hypersensitivity reactions. Patient monitoring after the injection (blanching or other warning signs) can facilitate prompt management.
Full correction requires several sessions. After results are achieved, patients should be reassessed every 3-6 months. Treatment touch-ups usually occur at a frequency of about every 6-9 months.
Hyaluronic acid fillers have gained popularity in recent years. To achieve naturally appearing results and minimize the risk for adverse events, it is important to gain mutual agreement on realistic treatment goals, select the most appropriate fillers based on an understanding of physical properties and rheologic characteristics, and follow meticulous advanced injection techniques. Patient education to clearly set expectations about post-injection care, timelines required to see optimal results, and the need for repeat injections is also important to optimize patient satisfaction, safety, and outcomes.
Beleznay K, et al. Dermatol Surg. 2015;41(10):1097-1117.
Chopra J, et al. J Drugs Dermatol. 2018;17(1):10-16.
Costa CR, et al. Plast Reconstr Surg. 2016;138:233e.
ade Maio M, et al; Alliance for the Future of Aesthetics Consensus Committee. Plast Reconstr Surg. 2017;140(2):265e-276e.
bde Maio M, et al; Alliance for the Future of Aesthetics Consensus Committee. Plast Reconstr Surg. 2017;140(4):540e-550e.
Fulton J, et al. J Drugs Dermatol. 2012;11(9):1098-1103.
Hilton L. Facial Anatomy At A Glance. Available at: http://aestheticchannel.modernmedicine.com/aesthetic-channel/news/facial-anatomy-glance?page=0,3. Accessed April 9, 2018.
Kerscher M, et al. Dermatol Surg. 2008;34:720-727.
Landau M, Fagien S. Plast. Reconstr Surg. 2015;136:188S.
Paliwal S, et al. Plast Reconst Surg. 2014;134:1224-1233.
Pierre S, et al. Dermatol Surg. 2015;41:S120–S126.
Signorini M, et al; Global Aesthetics Consensus Group. Plast Reconstr Surg. 2016;137:961e.
US Food and Drug Administration. Approved Dermal Fillers. Available at: https://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/CosmeticDevices/WrinkleFillers/ucm227749.htm#approved. Accessed April 9, 2018.
Van Loghem JAJ, et al. Aesthet Surg J. 2016;38(1):73-88.
Participate in the following ECHO™ —a digital reinforcement tool that emphasizes content from the Aesthetics activity series.
Minimally invasive, soft tissue filler use continues to rise in the US and plays an integral part in the correction of aesthetic changes associated with aging. The microinjections and blunt-tip cannula injections provide experienced aesthetic practitioners with an alternative to traditional dermal fillers. This educational activity will highlight some important factors to consider as you improve your technique and implement these advanced techniques into your practice.
Dr. Palm receives consulting fees from Allergan, Ampersand, BTL, Galderma, ISDIN, Lumenis, Lutronic, and Merz; is a speaker for non-CME services for Allergan, BTL, Galderma, Lutronic, and Merz; and conducts contracted research with Allergan, Ampersand, and Galderma.
Dr. Bloom receives consulting fees from Allergan, Aqua Pharmaceuticals, Cearna/OcuMend, Endo Pharmaceuticals, Galderma, InMode, MEND Nutrition, Merz, Remedly, Revance, RightResult, Sinclair, and ThermiAesthetics; is a speaker for non-CME services for Allergan, Alma Lasers, Galderma, InMode, Merz, and ThermiAesthetics; conducts contracted research with Allergan, Galderma, and Zeltiq; and has ownership interest in Cearna/OcuMend, MEND Nutrition, and Remedly.
This activity is supported by an independent educational grant from Galderma Laboratories, LP.


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The Inborn Absolute: The Artwork of Robert Ryan (Hardcover)
By Robert Ryan (Artist), Genesis P. Orridge (With), Freddy Corbin (With)
(ART)
This monograph delves into the career of celebrated artist Robert Ryan. From his early roots as a musician and painter, he discovered tattooing and quickly became one of the preeminent artists in that realm. His work reveals a deep mastery of the American tattooing tradition while creating a mystical and fantastic world full of unique takes on Eastern religious iconography. The book covers two decades of stunning paintings & tattoos, interviews with art and music luminaries about his work and subject matter, detailing Ryan's personal journey and progression as an artist.
Robert Ryan lives in Asbury Park NJ where he has been painting and tattooing for 20 years, taught in the classic traditional American style of bold line, heavy shading and solid field of color. His knowledge of Eastern Spirituality, Western Mysticism, and Amazonian Shamanism are all distilled through the filter of this powerful folk tattoo aesthetic. Robert's work has been featured in many galleries, schools, and publications world wide. As a musician he has released albums with the bands Lord Sterling, Out Like Lambs, and Harmonize Most High as well as his solo effort American Cloud Songs. Continuing to take many pilgrimages to India, Nepal and Peru, learning from Curanderos, Sadhus, Tantrics, and Monks, his work has tapped into a hidden knowledge which can only be passed down through the oral traditions and ancient practices.
Publisher: Featherproof Books
Publication Date: August 9th, 2016
Subjects & Themes - Religious
Body Art & Tattooing

redpajama_set_name: RedPajamaCommonCrawl


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Solly Zuckerman, Baron Zuckerman (1904–1993)
Elisabeth Frink	(1930–1993)
© The Executors of the Frink Estate and Archive. All Rights Reserved, DACS 2020. Photo credit: National Portrait Gallery, London
Zuckerman was a scientist, teacher of anatomy and pioneer in the study of primate behaviour. Chief Scientific Adviser to the government from 1966 to 1971, Zuckerman's publications include 'The Social Life of Monkeys and Apes' from 1931 and 'Scientists and War' from 1966.
Read more on National Portrait Gallery, London
H 31.1 x W (?) x D (?) cm
Signature/marks description
St Martin's Place, London, Greater London WC2H 0HE England
This venue is open to the public. Not all artworks are on display. If you want to see a particular artwork, please contact the venue.
Warrior II Dorset County Museum
Dog Dorset County Museum
Dog National Galleries of Scotland, Scottish National Gallery of Modern Art
The Stabbing The Ingram Collection of Modern British and Contemporary Art
Lying Down Horse The Ingram Collection of Modern British and Contemporary Art
Green Head The Ingram Collection of Modern British and Contemporary Art
Riace III Yorkshire Sculpture Park


Pass Your IBM Certified Database Administrator - DB2 11 DBA for z/OS Exams - 100% Money Back Guarantee!
The aim of the certification is to provide candidates with skills on DB2. The individual is shown how to implement in DB2, a logical design- a database one, how to manage DB2 data, catalog tables in DB2,bind process, the database utilities includingREORG and LOAD and the security considerations.These programmers will get a know-howon creating, administering and maintaining DB2 9 databases in the z/OS platform & implementing XML with the DB2 database.
The certification can be done by those with the need for acquiring the basic skills that are required in the administration of DB2 database.
The database administrator will be knowledgeable in DB2 specifically the functionality and new features that are related to the version 9. The DBA will have the capability of performing both advanced and intermediate tasks that are related to implementation and database design, recovery and operation, auditing and security, performance, installation and upgrades or migration specific to z/OS operating systems.
Before one begins to prepare for the IBM Certified Database Administrator: DB2 9 DBA for z/OS certification, he or she must possess the following skills and experiences: must be experienced as being a database administrator on the DB2 9 for z/OS, have at least 2 years of experience in administration of database for z/OS operating system, be knowledgeable and experienced in system programming and application DBA areas, have knowledge of the major languages used in programming ranging from Java, C++ and COBOL and have the capability of working effectively and independently in any complex environment. The candidate can also do the following recommended courses but it is good to note that the courses are not a requirement before you attempt this certification test: DB2 9 database administration certification study guide, DB2 9 for z/OS implementation workshop, DB2 9 for z/OS database administration workshop part 2, SQL workshop, DB2 9 for z/OS database administration workshop part 2 and DB2 fundamentals.
The two tests require an individual to concentrate on all the sections and do a thorough study on them. More examination preparation tools and details of the examination sections are on the website of the vendor.
The candidate is allowed to answer the 69 questions in this exam in a duration of 90 minutes which is equivalent to one hour and thirty minutes. 57% is the pass mark required for this test. This exam does not have assignments or essays that that require to be submitted. The full exam topics list can be accessed in the provider's website.
This certification does not expire.
The sequence listing order of the steps does not matter in completion of the steps but the last step must be after you complete the other steps.
This IBM certification will assist you in laying your personal journey groundwork that will lead you to becoming a world class resource to both your colleagues, customers, and company by providing you with the appropriate knowledge and skills that are needed for your success.


Highways England is reported to be proposing a ban on cyclists using a stretch of one of its roads near Hull. The A63 Trunk Road forms part of the V718 course on which Marcin Bialoblocki set the 10-mile time trial record of 16m35s in 2016, but Highways England wants all cyclists excluded for safety reasons.
Writing on the Hull Thursday Road Club Facebook page, Club Time Trial Secretary Paul Kilvington said that he had received a number of reports that Highways England was proposing a Traffic Regulation Order to ban cyclists from the A63.
He later posted a copy of the document.
"Concerns have been raised for the safety of cyclists using the A63 Trunk Road between North Cave Interchange and Daltry Street Interchange. Cyclists are travelling on a carriageway that carries average speeds of 65mph for traffic, at a rate of over 2,500 vehicles per hour. In the last 5 years there have been six accidents involving cyclists, including a fatality in 2013.
"In the interest of road safety, Highways England Company Limited is proposing to ban cyclists on this stretch of road, including the associated slip roads.
The document states that the consultation period closes on February 19.
In 2013, a coroner's court returned a finding of accidental death after a rider in a time trial died following a collision with a stationary caravan on the A63.
Christopher Auker, 65, riding in a tuck and looking downwards, realised the danger at the last moment and was unable to avoid hitting the caravan, whose driver had pulled over after a puncture. He sustained head, spinal and thoracic injuries and died at the scene.
Speaking after the incident, Auker's widow Elizabeth said: "Neither Chris nor I had any worries about this course – we both felt time-trials were safer on a dual carriageway where there is room for traffic to overtake.
In 2015, then World Time Trial Champion, Sir Bradley Wiggins, rode Hull City Road Club's 10-mile time trial on the A63. Footage of him riding the course can be seen here.
Highways England has been contacted for further comment.


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Posts tagged 'renewable energy'
China to create $3 billion solar fund for Pakistan China to support Pakistan in utilising its solar energy resources
A Chinese company is ready to create a special solar fund worth three billion dollars in China to support Pakistan in utilising its solar energy resources. The company has the capacity to establish a solar plant of 1000MW in 6 to 8 months in Pakistan, while 50MW to 100 MW solar energy can be…http://alternativeenergy.com.pk/solar-energy-power/china-to-create-3-billion-solar-fund-for-pakistan-china-to-support-pakistan-in-utilising-its-solar-energy-resources/ Alternative Energy, Alternative Energy in Pakistan, Alternative Energy News, batteries, Biofuels, biogas, biomass, Board of Investment (BoI), Charge Controller, Electricity, Energy, Energy Crises, Energy Crises in Pakistan, Energy News, green energy, Hydel Energy, Hydropower, Inverter, LED lights, LVD Induction Lamps, PAKISTAN, Pakistan Renewable Energy Society, renewable energy, Renewable Energy Financing, Renewable Energy News, Renewable Energy NGOs, Renewable Energy NGOs in Pakistan, Renewable Energyin Pakistan, solar energy, solar energy resources, Solar Panels, solar Street lights, solar water heaters, Solar Water Pumping, Wind energy
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Alternate energy tech can resolve energy crisis Pakistan China Joint Chamber of Commerce and Industry (PCJCCI)
Alternate energy tech or Education President, Pakistan China Joint Chamber of Commerce and Industry (PCJCCI) Shah Faisal Afridi has said that acquisition of renewable energy and alternate energy technology such as solar, wind power, run of river, coal power plants from China could help…http://alternativeenergy.com.pk/education-training/alternate-energy-tech-can-resolve-energy-crisis-pakistan-china-joint-chamber-of-commerce-and-industry-pcjcci/ Alternate energy education in Pakistan, alternate energy technology, China Energy Engineering Group (CEEC), coal power plants, renewable energy, resolve energy crisis, run of river, solar, wind power
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Renewable energy use gaining worldwide: IEA fastest-growing source of energy power generation
Renewables like solar and wind represent the fastest-growing source of energy power generation and will make up a quarter of the global power mix by 2018, the International Energy Agency said in a report Wednesday. The IEA said that in 2016 renewable energy will overtake natural gas as a power…http://alternativeenergy.com.pk/renewable-energy/renewable-energy-use-gaining-worldwide-iea-fastest-growing-source-of-energy-power-generation/ energy power generation, renewable energy
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Seychelles plugs in to renewables with 6MW wind farm by Masdar and funded by the Abu Dhabi Fund for Development (ADFD)
Abu Dhabi renewables company Masdar – majority owner of the world's largest concentrating solar power plant, which launched in March – has today announced the launch of a 6MW, eight-turbine wind farm in the Republic of Seychelles, marking the French archipelago's first ever renewables…http://alternativeenergy.com.pk/solar-energy-power/seychelles-plugs-in-to-renewables-with-6mw-wind-farm-by-masdar-and-funded-by-the-abu-dhabi-fund-for-development-adfd/ Abu Dhabi Fund for Development (ADFD), Abu Dhabi renewables company Masdar, renewable energy, world's largest concentrating solar power plant
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Global Carbon Emissions Reached Record High In 2012 according to the International Energy Agency
Global carbon emissions reached a new high in 2012, rising by 1.4% to 31.6 billion tons, according to the International Energy Agency. The large rise in emissions was led by China, which released 300 million more tons in 2012 than it did in 2011.
Image Credit: Climate Change via Flickr CC
As…http://alternativeenergy.com.pk/environment/global-carbon-emissions-reached-record-high-in-2012-according-to-the-international-energy-agency/ energy efficiency, Global Carbon Record High In 2012, International Energy Agency, renewable energy
Global Carbon Record High In 2012
Graph of the Day: How green is your country? he level of renewable energy in the electricity systems of countries across the globe
Today's Graph of the Day comes courtesy of The Energy Collective, and gives an interesting perspective of the level of renewable energy in the electricity systems of countries across the globe: the lighter the green, the higher the percentage of renewables.
But appearances can be deceiving….http://alternativeenergy.com.pk/press-release/graph-of-the-day-how-green-is-your-country-he-level-of-renewable-energy-in-the-electricity-systems-of-countries-across-the-globe/ electricity systems, Energy Collective, percentage of renewables, renewable energy
electricity systems
Energy Collective
percentage of renewables
Are Solar Panels Worth the Cost? recent event on renewable energy choices,
At a recent event on renewable energy choices, a proud homeowner showed a picture of his gleaming new rooftop PV array, and pointed out that he'd chopped down all the trees on his lot to make sure nothing got in the way of his roof.
I chuckled, having just planted some trees to save money…http://alternativeenergy.com.pk/renewable-energy/are-solar-panels-worth-the-cost-recent-event-on-renewable-energy-choices/ Efficiency, Electricity, energy efficiency, Green Business, new rooftop PV, reduction program, renewable energy, Renewables, Solar Panels, Solar Power, trees
new rooftop PV
reduction program


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This is the primary directory for the Fred Hutch natural language processing engine for the parsing of clinical documents and the classification and automated extraction of clinical data elements
----------------------------------------------------------------------------------------------------------------
- command_line_flags.txt
	a tab delimited text file containing command line flags and their descriptions in the format:
	flag __tab__ required or not_required __tab__ short_description __tab__ long_description

*required flags*

	* -t = type of report (e.g. 'pathology' or 'cytogenetics')
	* -f = path to the input file
	* -o = name of the output file (this will right to the argos_nlp directory)
	* -g = disease group ('all' will prompt the engine to classify the disease group if the report type == pathology)

*optional flags*

	* -ml = machine learning flag, this defaults to 'n' which means the engine will not require the language models needed to run the machine learning algorithms
	* -a = algorithm flag, this defaults to 'y', which means the engine will run appropriate algorithms. If input parameter == 'n', then the engine will simply output text and tsv files.

- global_strings.py: a set of string variables used in various scripts in this directory

- make_text_output_directory.py: a python script to create a directory for output text files (the directory location is expected to match the input file name location)

- metadata.json: a json document that houses all the relevant metadata for all document types, tables, fields, etc. This data is used to parse output and population dropdown fields in the user interface

- metadata.py: 	a script to create a dictionary/json object that lists relevant metadata for the batch run
	(potential fields values, etc) this document and disease group specific metadata (full version read in from metadata.json) will be used to population dropdowns in the front end/abstraction LabKey interface

- nlp_engine.py: the primary script for the natural language processing engine.  This requires a set of flagged command line arguments as well as the command_line_flag file which gives their mappings, and input document(s)

- output_results.py: output the final JSON object to the location specified by the command line -o flag

- version: a text file with the version number which is automatically updated by the post commit hook script

- schema.json: 	a json schema that dictates the appropriate output format for the engine (currently validation is an offline process)

- fhcrc_pathology: a directory of modules for processing pathology reports
- fhcrc_cytogenetics: a directory of modules for processing cytogenetics reports

redpajama_set_name: RedPajamaGithub


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Nathalie Reuter
Reuter group web pages
E-mailNathalie.Reuter@uib.no
Phone+47 55 58 40 40+47 454 13 660
Høyteknologisenteret, Datablokk, 5th floor
Thormøhlensgt 55
Molecular Modeling and Simulations. Bioinformatics. Proteins' Flexibility and Dynamics. Membrane-binding proteins. Drug discovery.
MOL204 - Applied bioinformatics I
MOL217 - Applied bioinformatics II
Show author(s) (2021). Phospholipids in Motion: High-Resolution 31 P NMR Field Cycling Studies. Journal of Physical Chemistry B. 8827-8838.
Show author(s) (2021). Membrane models for molecular simulations of peripheral membrane proteins. Advances in Physics: X.
Show author(s) (2021). Martini 3: a general purpose force field for coarse-grained molecular dynamics. Nature Methods. 382-388.
Show author(s) (2020). Visual exploration of large normal mode spaces to study protein flexibility. Computers & graphics. 73-83.
Show author(s) (2020). The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection. The FEBS Journal. 4458-4480.
Show author(s) (2020). Levels of proteinase 3 and neutrophil elastase in plasma, BAL and biopsies in COPD. European Respiratory Journal.
Show author(s) (2020). Dynamics-function relationship in the catalytic domains of N-terminal acetyltransferases. Computational and Structural Biotechnology Journal. 532-547.
Show author(s) (2020). Classification and phylogeny for the annotation of novel eukaryotic GNAT acetyltransferases. PLoS Computational Biology. 1-29.
Show author(s) (2020). Capturing Choline–Aromatics Cation−π Interactions in the MARTINI Force Field. Journal of Chemical Theory and Computation.
Show author(s) (2019). Peptidomimetic inhibitors targeting the membrane-binding site of the neutrophil proteinase 3. Biochimica et Biophysica Acta - Biomembranes. 1502-1509.
Show author(s) (2019). Interfacial Aromatics Mediating Cation−π Interactions with Choline-Containing Lipids Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted below the Phosphates. The Journal of Physical Chemistry Letters. 3972-3977.
Show author(s) (2019). Cation‐π Interactions between Methylated Ammonium Groups and Tryptophan in the CHARMM36 Additive Force Field. Journal of Chemical Theory and Computation. 7-12.
Show author(s) (2018). Structure and dynamics of the N-terminal acetyltransferase family: a computational study.
Show author(s) (2018). Search and subvert: Minimalist bacterial phosphatidylinositol-specific phospholipase C enzymes. Chemical Reviews. 8435-8473.
Show author(s) (2018). D-peptides as inhibitors of PR3-membrane interactions. Biochimica et Biophysica Acta - Biomembranes. 458-466.
Show author(s) (2018). Conservation of intrinsic dynamics in proteins-what have computational models taught us? Current Opinion in Structural Biology. 75-81.
Show author(s) (2018). A model for hydrophobic protrusions on peripheral membrane proteins. PLoS Computational Biology. 1-26.
Show author(s) (2017). Molecular determinants of the N-Terminal acetyltransferase Naa60 anchoring to the Golgi membrane. Journal of Biological Chemistry. 6821-6837.
Show author(s) (2017). Interactions stabilizing the C-terminal helix of human phospholipid scramblase 1 in lipid bilayers: A computational study. Biochimica et Biophysica Acta - Biomembranes. 1200-1210.
Show author(s) (2016). Similarity in Shape Dictates Signature Intrinsic Dynamics Despite No Functional Conservation in TIM Barrel Enzymes. PLoS Computational Biology. 26 pages.
Show author(s) (2016). Role of noncovalent interactions in protein peripheral membrane binding. Computational perspectives.
Show author(s) (2016). Proteinase 3 is a phosphatidylserine-binding protein that affects the production and function of microvesicles. Journal of Biological Chemistry. 10476-10489.
Show author(s) (2016). Improving the force field description of tyrosine-choline cation-π interactions: QM investigation of Phenol-N(Me)4 Interactions. Journal of Chemical Theory and Computation. 5585-5595.
Show author(s) (2016). A Role for Weak Electrostatic Interactions in Peripheral Membrane Protein Binding. Biophysical Journal. 1367-1378.
Show author(s) (2015). Quantifying transient interactions between bacillus phosphatidylinositol-specific phospholipase-C and phosphatidylcholine-rich vesicles. Journal of the American Chemical Society. 14-17.
Show author(s) (2015). Membrane docking of the synaptotagmin 7 C2A domain: computation reveals interplay between electrostatic and hydrophobic contributions. Biochemistry. 5696-5711.
Show author(s) (2015). Comparing the intrinsic dynamics of multiple protein structures using elastic network models. Biochimica et Biophysica Acta - General Subjects. 911-922.
Show author(s) (2015). Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects. Human Molecular Genetics. 1956-1976.
Show author(s) (2014). WEBnm@ v2.0: Web server and services for comparing protein flexibility. BMC Bioinformatics.
Show author(s) (2014). Two homologous neutrophil serine proteases bind to POPC vesicles with different affinities: When aromatic amino acids matter. Biochimica et Biophysica Acta - Biomembranes. 3191-3202.
Show author(s) (2014). Synthesis and biological evaluation of pseudopeptide inhibitors of Proteinase 3.
Show author(s) (2014). Reversible ketomethylene-based inhibitors of human neutrophil proteinase 3. Journal of Medicinal Chemistry. 9396-9408.
Show author(s) (2014). In silico, in vitro and in vivo models reveal functional impairment of the Ogden syndrome N-terminal acetyltransferase Naa10 S37P mutant.
Show author(s) (2014). In silico design, synthesis, and assays of specific substrates for proteinase 3: Influence of fluorogenic and charged groups. Journal of Medicinal Chemistry. 1111-1115.
Show author(s) (2014). Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science.
Show author(s) (2014). Characterization of immunological cross-reactivity between enterotoxigenic Escherichia coli heat-stable toxin and human guanylin and uroguanylin. Infection and Immunity. 2913-2922.
Show author(s) (2014). Automated Enzyme Function Inference in Archaea Genomes:comparison of PRIAM and EFICAZ.
Show author(s) (2013). Visual cavity analysis in molecular simulations. BMC Bioinformatics.
Show author(s) (2013). Probing for π-Cation Interactions in the Binding of B. Thuringiensis Phosphatidylinositol-Specific Phospholipase C Phosphatidylcholine-Rich Vesicles.
Show author(s) (2013). Probing for pi-cation interactions in the binding of B. thuringiensis phohosphatidylinositol-specific phospholipase C phosphatidylcholine-rich vesicles. Biophysical Journal. 363A-364A.
Show author(s) (2013). Expert system for mining and sifting novel enzyme sequences in metagenomics data.
Show author(s) (2013). Examining the flexibility of tim barrel proteins based on their structural topology. Biophysical Journal. 227A-228A.
Show author(s) (2013). Evaluation of protein elastic network models based on an analysis of collective motions. Journal of Chemical Theory and Computation. 5618-5628.
Show author(s) (2013). Does changing the predicted dynamics of a phospholipase C alter activity and membrane binding? Biophysical Journal. 185-195.
Show author(s) (2013). Comparing normal modes of protein structures using Webnm@ 2.0. Biophysical Journal. 228A-228A.
Show author(s) (2013). Comparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymes. Proteins: Structure, Function, and Bioinformatics. 63-80.
Show author(s) (2013). Characterization of cytosolic proliferating cell nuclear antigen (PCNA) in neutrophils: anti-apoptotic role of monomeric PCNA. European Journal of Clinical Investigation. 20-20.
Show author(s) (2013). Cation-π interactions as specific anchors for B. Thuringiensis PhosphoInositol-specific PhosphoLipase-C binding to Phosphatidylcholine bilayer.
Show author(s) (2013). Cation-π interactions as lipid specific anchors for phosphatidylinositol-specific phospholipase-C.
Show author(s) (2013). Cation-pi Interactions As Lipid-Specific Anchors for Phosphatidylinositol-Specific Phospholipase C. Journal of the American Chemical Society. 5740-5750.
Show author(s) (2013). Cation-PI interactions as specific anchors for B. thurigiensis phosphoinositol-specific phospholipase-C binding to phosphatidylcholine bilayer. Biophysical Journal. 536A-536A.
Show author(s) (2013). Aromatic amino acid distribution in peripheral membrane proteins. .
Show author(s) (2012). Structural modeling and kinetic studies of a mutant N-terminal acetyltransferase, hNaa10p Ser37Pro, causing an infantile lethal disorder.
Show author(s) (2012). Specificity and Versatility of Substrate Binding Sites in Four Catalytic Domains of Human N-Terminal Acetyltransferases. PLOS ONE.
Show author(s) (2012). PR3 Interacts Directly to Lipid Bilayers: Evidence from MD Simulations and SPR Experiments. Biophysical Journal. 497A-497A.
Show author(s) (2012). PR3 Interacts Directly to Lipid Bilayers: Evidence from MD Simulations and SPR Experiments.
Show author(s) (2012). Nuclear-to-cytoplasmic Relocalization of the Proliferating Cell Nuclear Antigen (PCNA) during Differentiation Involves a Chromosome Region Maintenance 1 (CRM1)-dependent Export and Is a Prerequisite for PCNA Antiapoptotic Activity in Mature Neutrophils. Journal of Biological Chemistry. 33812-33825.
Show author(s) (2012). Measuring and comparing structural fluctuation patterns in large protein datasets. Bioinformatics. 2431-2440.
Show author(s) (2012). Implicit Surfaces for Interactive Graph Based Cavity Analysis of Molecular Simulations. 9 pages.
Show author(s) (2012). Anchoring of PI-PLC to DMPC Bilayers Involves Specific Cation-PI Interactions. Biophysical Journal. 78A-79A.
Show author(s) (2012). Anchoring of PI-PLC to DMPC Bilayers Involves Specific Cation-PI Interactions.
Show author(s) (2012). An x-linked infantile lethal disorder caused by N-terminal acetyltransferase deficiency.
Show author(s) (2012). A dynamic model of long-range conformational adaptations triggered by nucleotide binding in GroEL-GroES. Proteins: Structure, Function, and Bioinformatics. 2333-2346.
Show author(s) (2011). Principal component and normal mode analysis of proteins; a quantitative comparison using the GroEL subunit. Proteins: Structure, Function, and Bioinformatics. 232-243.
Show author(s) (2011). NUCLEOCYTOPLASMIC RELOCALIZATION OF THE PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) DURING DIFFERENTIATION IS ESSENTIAL FOR ITS ANTIAPOPTOTIC ACTIVITY IN MATURE NEUTROPHIL: IDENTIFICATION OF A NUCLEAR EXPORT SEQUENCE. Inflammation Research. 37-37.
Show author(s) (2011). Molecular analysis of the membrane insertion domain of proteinase 3, the Wegener's autoantigen, in RBL cells: implication for its pathogenic activity. Journal of Leukocyte Biology. 941-950.
Show author(s) (2011). Mechanistic Investigation of Aromatic Amino Acid Hydroxylases. A Density Functional Theory Study.
Show author(s) (2011). Interactive Visual Analysis of Temporal Cluster Structures. Computer Graphics Forum. 711-720.
Show author(s) (2011). Integrating Cluster Formation and Cluster Evaluation in Interactive Visual Analysis. 8 pages.
Show author(s) (2011). Exploring the factors determining the dynamics of different protein folds. Protein Science. 197-209.
Show author(s) (2011). Dynamics, flexibility and ligand induced conformational changes in biological macromolecules: a computational approach. Future Medicinal Chemistry. 2079-2100.
Show author(s) (2011). Conformational sampling and nucleotide-dependent transitions of the GroEL subunit probed by unbiased molecular dynamics simulations. PLoS Computational Biology.
Show author(s) (2011). Comparison of PR3 and PI-PLC binding to a DMPC bilayer.
Show author(s) (2010). Structures of human proteinase 3 and neutrophil elastase - so similar yet so different. The FEBS Journal. 2238-2254.
Show author(s) (2010). Proliferating cell nuclear antigen acts as a cytoplasmic platform controlling human neutrophil survival. Journal of Experimental Medicine (JEM). 2631-2645.
Show author(s) (2010). Molecular Dynamics Simulations of Mixed Acidic/Zwitterionic Phospholipid Bilayers. Biophysical Journal. 825-833.
Show author(s) (2010). Interaction of proteinase 3 with its associated partners: implications in the pathogenesis of Wegener's granulomatosis. Current Opinion in Rheumatology. 1-7.
Show author(s) (2010). How does Proteinase 3 interact with lipid bilayers? Physical Chemistry, Chemical Physics - PCCP. 7487-7496.
Show author(s) (2009). Normal mode analysis for proteins. Journal of Molecular Structure: THEOCHEM. 42-48.
Show author(s) (2009). Mutagenesis analysis of the insertion domain of proteinase 3 into membrane: a potential target for anti-inflammatory therapy in vasculitis. APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 121-121.
Show author(s) (2009). Challenges in pK(a) Predictions for Proteins: The case of Asp213 in Human Proteinase 3. Journal of Physical Chemistry A. 11783-11792.
Show author(s) (2008). Computational prediction of the binding site of proteinase 3 to the plasma membrane. Proteins: Structure, Function, and Bioinformatics. 1655-1669.
Show author(s) (2007). Two-Level Approach to Efficient Visualization of Protein Dynamics. IEEE Transactions on Visualization and Computer Graphics. 1616-1623.
Show author(s) (2007). TMM@: a web application for the analysis of transmembrane helix mobility. BMC Bioinformatics. 8 pages.
Show author(s) (2007). Molecular modeling of the substrate specificity and of the membrane anchoring of Proteinase 3.
Show author(s) (2007). Influence of charge distribution at the active site surface on the substrate specificity of human neutrophil protease 3 and elastase - A kinetic and molecular modeling analysis. Journal of Biological Chemistry. 1989-1997.
Show author(s) (2007). Differences in the substrate binding sites of murine and human proteinase 3 and neutrophil elastase. FEBS Letters. 5685-5690.
Show author(s) (2007). Bioinformatikk anvendt på lokalanestetikas virkningsmekanisme. Den norske tannlegeforenings tidende. 672-675.
Show author(s) (2006). Inspection of the binding sites of proteinase3 for the design of a highly specific substrate. Journal of Medicinal Chemistry. 1248-1260.
Show author(s) (2006). Evaluation of models for the evolution of protein sequences and functions under structural constraint. Biophysical Chemistry. 134-144.
Show author(s) (2006). A novel locust (Schistocerca gregaria) serine protease inhibitor with a high affinity for neutrophil elastase. Biochemical Journal. 467-476.
Show author(s) (2005). WEBnm@: a web application for normal mode analyses of proteins. BMC Bioinformatics.
Show author(s) (2005). Normal mode-based fitting of atomic structure into electron density maps: Application to sarcoplasmic reticulum Ca-ATPase. Biophysical Journal. 818-827.
Show author(s) (2005). Cleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Journal of Biological Chemistry. 30242-30253.
Show author(s) (2004). The norwegian bioinformatics platform.
Show author(s) (2004). Normal modes of the Ca2+-ATPase based on a comparison between the E1Ca2 and E2TG structures.
More information in national current research information system (CRIStin)
Fields of competence
Membrane-binding proteins.
Proteins' flexibility and dynamics.
Molecular modeling and simulations
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