"Signal-to-noise ratio" is an engineering concept that focuses on the amount of useful information being received compared with false or useless data. This is an especially important concept to investors.
Over the past few years, I have been reducing the meaningless distractions in my investing process. You should, too. You want less of the annoying nonsense that interferes with your portfolios and more of the significant data that allow you to become a less distracted, more purposeful investor.
This is a continual process of refinement. Finding moments of quiet contemplation that allow you to think things through is an important aspect of investing. Uninterrupted time with no distractions — no TV or instant messages or tweets — is increasingly rare in our society, and all the more important for that reason. And I don't mean just quiet time in front of your computer screen — such activities as jogging, yoga, even meditation can get you out of your routine and provide an opening for deep thought.
Daniel J. Boorstin, who served as the librarian of the U.S. Congress, once said that "I write to discover what I think," and that is my own process. I wake before dawn and sketch out my thoughts on what is happening in the market or the economy. (They show up on my blog). I have found that articulating my perspective in a coherent and structured format is an enormous aid to my understanding. It is more of an editing process, deciding what to remove. Indeed, I spend much of this quiet time deciding what is not worthwhile.
As a professional investor, I find this to be liberating and productive. We are all so distracted by meaningless minutiae. Most of our daily inputs — news, company releases, economic tidbits, punditry — turn out to be distracting irrelevancies that should not affect our investments.
After this editing process, what is left is almost all signal, and no noise.
It is not an easy thing to do. Removing the noise is a fight against habits. Your daily routines are probably filled with noisy and unimportant inputs. But getting to the good stuff buried within that junk is important.
Think about these inputs and what they mean to your investing process. Do they increase or decrease the noise levels?
● News: Most of it is actually old. By the time information hits the papers, it's pretty much already in the stock price.
● TMI: Too much information can lead to the paradox of overconfidence and bad investment decisions.
● Anecdotes: A good narrative is more compelling than statistical data, but the data are more determinative of future returns.
● Talking heads: Your goal is to safely grow your assets — but what are the goals of those you see on TV? What's their agenda?
● Short-term goals: How much of your information consumption is short-term, meaningless noise?
As a thought experiment, consider what would happen if you purposefully tried to assemble a "how-to" list in pursuit of the exact opposite goal we're talking about here — if you wanted to get much more noise and much less signal? In other words, what are exactly the wrong things to do as an investor?
(1) Constantly consume mainstream media. Financial television is an excellent source of actionable investing ideas.
(2) Play down data. It's overrated. Stick with anecdotes from people you know personally and your gut instincts.
(3) Pay attention to pundits. They exist for the sole purpose of helping you reach a comfortable retirement.
(4) Get the inside dope. All of the important information about the stock market — especially when it is going to crash or rally — is known only to handful of secret insiders. If you can't get their magic knowledge, blame them for any losses you incur.
(5) Stress about this. Exert lots of energy, spend lots of time and create lots of tension about all of the following: Federal Reserve and the Taper, the Dollar versus the Euro, the Tea Party and Congress, Hyper-Inflation, European Sovereign Bank Debt, Gold, China, Deflation, Austerity and the Hindenburg Omen.
(6) Don't do the math. Numbers are vastly overrated, and probability analysis is for geeks anyway.
(7) Stay in your comfort zone. Focus only on those news sources that are in sync with your politics. Seek out sources that confirm your preexisting opinions and investment postures. Never read anything that challenges your beliefs.
(8) Think fast. Trading is where the big money is made! Don't worry about the long term — it's way off in the future. Measure your success in hours and days, not years and decades.
(9) Have a Super Happy Fun Time. There is no reason that you cannot also have a good time with your retirement account: It's tax -deferred, so you have no capital gains consequences. Have fun with it — that's what it's there for anyway!
(10) Ask: What Have You Done For Me Lately? Never listen to people with good long-term track records who may have had a losing period. When Warren Buffett underperformed in 1999, you should have written him off. Investing is about recent performance!
These guidelines are sarcastic, of course, but I recognize a lot of bad behavior I see all the time from investors. It is a recipe for lots of noise and very little signal.
How much noise do you have in your investing process?
Ritholtz is chief investment officer of Ritholtz Wealth Management. He is the author of "Bailout Nation" and runs a finance blog, the Big Picture. Twitter: @Ritholtz.


He'd like nothing more than to get rid of the Bible he found in the wreckage of a derelict starship. It's brought trouble — the secret police are closing in on him. He's fighting more with his father. And he fears that the young woman he loves may be falling under the book's spell. But he can't seem to let it go.
Now he's sharing what he's read with believers who have awaited the return of God's Word for decades. His mysterious rescuer, Jason, wants the Bible taken to a safe place. So now it's his choice. He can hide it, or proclaim it. With Kesek in control of the Realm and coming after all its opponents, Baden will have to trust not only in his friends but in a contingent of elite soldiers determined to save the king. He'll have to come to grips with the power he has unleashed on the Realm of Five. And that power has plans of its own.
Book 2 of The Face of the Deep series.


Sustainable Cleveland 2019 is a 10-year initiative to catalyze action and create a vibrant sustainable economy for the City of Cleveland. The SC2019 Action and Resources Guide was prepared to align and guide all future Sustainable Cleveland 2019 activities. Studio Graphique was tasked with developing a brand identity for Sustainable Cleveland 2019 as well as a comprehensive design for the final guide.
The brand elements include an iconic shape symbolic of both the seeds we plant and the life that emerges from them. Working together they can create endless combinations. The brand was then extended to online platforms including a website, Facebook and Twitter skins, and a physical space: The Sustainable Cleveland Center. These platforms were integral for creating spaces for the community to work together and communicate openly on the efforts being made by the City and working groups.
© 2019 Studio Graphique All Rights Reserved.


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Malcolm Gladwell Challenges LeBron and Predicts an N.B.A. Champion
In this conversation with David Remnick, Gladwell talks about his life in running, his pick for the N.B.A. title, and why he challenged LeBron James to a race.
(pinging)
(intriguing, mysterious music)
You just did the ballsiest thing I've ever seen,
you challenged Lebron James to a race.
Are you out of your mind?
So there was this debate about whether
Lebron can break five minutes for the mile.
And someone, because I am sort of around there,
someone suggested, well you should just
challenge him to a race, I was like, alright.
So I challenged him.
He would destroy me, to be clear.
In the race?
There was actually an online poll
conducted by Sports Illustrated about who would win.
And I voted for Lebron,
I think Lebron can run probably a 4:40 mile.
And I think the fact that he's 6'8 and 250
is beside the point.
I think his cardiovascular system is off the charts.
And I am, to be clear, 54 years old.
And he's 34 and considered an old man in the NBA.
You're an incredibly passionate runner.
My wife occasionally will see you running in Central Park.
This started out when you were a kid in Ontario.
There's a picture I've seen of you
breaking the tape in a 1,500 meter race
that you call the happiest moment of your life.
Greatest moment of my life, yeah.
And where was it?
That was
It was at Ontario Championships in 1978,
so I was 14, or 13, and I beat a guy who,
this is my great claim to fame,
who then went onto go to the Olympics.
And so, I, back the day, was better than a future Olympian.
You were the only person I know
that was thrilled to turn 50 because,
by turning 50, it put you in another division for racing,
and now you can beat the geezers and come in first.
Yeah, no I'm now I'm in the over 50 masters division.
How do you train?
Well, I've fallen in love with running heavy mileage,
which I never did it when I was younger.
So I run nine or ten miles a couple times a week.
And you're not bored to death,
running nine to ten miles doesn't hurt?
No, it's become increasingly important
because there's very little daydreaming time left.
You know, we used to daydream a lot.
You got your phone.
Back in the day, you daydreamed, now, you have your phone.
And daydreaming I think is insanely productive.
Do you get a lot of ideas running
Not directly or think things through?
but I'm sure indirectly.
I don't think you can be creative
unless your mind has some kind of free time.
I mean, this has been talked about to death
with the kind of phone addiction.
But one of your trade secrets is that you write in cafés.
In other words, you have a perfectly nice apartment,
you have a house out in the country.
And then you drive to a café,
or in the city, you walk to a café.
I don't understand this at all, why you'd wanna be
around other people and noise
and clattering forks and spoons.
It's because I came of age as a writer
in the Washington Post news room.
In fact now this is a crucial thing that will age us both.
Today's newsrooms are quiet.
That's right.
Our newsrooms
is noisy
Not just noisy.
You would get off the elevator
on the fifth floor of the Washington Post building,
and you would be hit by a wall of sound
which was 300 people talking loudly on the phone,
the clatter of keyboards, and people like yelling
One could only imagine typewriters
Oh, typewriters really... but I just, I love that.
I went into work each day waiting for that noise.
I loved that noise. You love noise.
One of the things that maybe running has sparked
in your mind is we're constantly talking about health care.
Health is only weakly correlated
with the health care system.
The things that make you healthy
are not doctors, nurses, hospitals, and drugs.
It's your diet, how well you exercise,
and your genes,
and your luck
and your luck.
We have convinced everyone that if only everyone had access
to the health care system, we would all be healthy.
That is nonsense.
Our real goal, when we talk about health,
should not be to perfect the health care system.
It should be to improve the health of Americans.
It has a lot more to do with eating properly
and getting, having the ability to exercise regularly.
When Mike Bloomberg wanted to put a tax on soda,
that was possibly one of the most important
health care initiatives of the past generation.
People treated it like it was a
civil rights decision
or a side show, it's not a side show!
He's absolutely right.
Would you tax McDonald's and
Oh my god, I would tax McDonald's through the roof.
The soda companies more than McDonald's actually.
I mean I really think we should be thinking
about soda the same way we thought about cigarettes.
I mean, it seems to be pretty clear
that they're in the same category
of incredibly harmful substances.
Is football on the same level as cigarettes?
Well, so I was gonna get to the exercise part of this.
That I think we need to re-think
the role of sports in our society.
We've got into this whole thing that the point of sports,
as a kid, is to be an elite athlete
and to perform at a high level
in that period of you teens, no!
What we should be doing is promoting
the kinds of sports that people can play
their entire life, or much of their lives.
And we should be permitting people
to play sports at a mediocre level.
You know, I was at Bard College,
which is near my house upstate,
and I was watching the Lacrosse team practice.
Bard probably has, I don't know
The 400th best Lacrosse team in the country.
But they're having fun.
They're having fun!
That is what college sports is supposed to be.
It's supposed to be anyone that wants
to play Lacrosse at Bard just shows up,
I'm sure, and is on the team.
And so those kids are running around,
having the time of their life, enjoying themselves,
and presumably, hopefully, laying down
a pattern of physical activity
that will be with them for the rest of their lives.
That is the goal, right?
At Hopkins, or at Duke, where Lacrosse is this thing,
you can't do that.
So you may wanna play Lacrosse, but unless you're
in the 99th percentile, it's forbidden to you.
That, to me, is crazy.
Yeah, if that shift happens in American life,
does that mean you won't get Lebron James
out the other end of the
No, I think you still get Lebron James.
If you look at marathon times in America 30 years ago,
the times were better than they are now.
I mean, when I say better, deeper.
The top 20 finishers at the Boston Marathon in 1978
was way more impressive than it is today.
But what's happened now is we've traded
elite performance for a much wider participation,
and that is exactly the trade-off we ought to be making.
Who's gonna win the NBA title this year?
Houston?
Well, I, can I name drop?
I got a call to a friend from Steve Kerr,
and he said you should come to a game,
come and say hi to us!
So I went to a game a couple weeks ago.
Man, what more could you ask for.
And I went back and I met Steph Curry
and KD and Andre Iguodala and Shaun Livingston
and I mean, I was just like, I mean
it was maybe one of the greatest evenings of my life.
This did not give me any special insight
into the Playoff Prospects, but they're too banged up.
And Houston is on another level.
I sort of think, I don't know, I sort of feel
like they're not as deep as they were in previous years.
And Cleveland?
I don't think Cleveland can,
I mean Houston's on a, is a, I mean
they've figured out this sort of
they've exploited, they've hacked basketball.
I think that no one else has
Who has?
caught up with them... Houston.
That if you've got this three point line,
maybe you should just do nothing but shoot
layups and three point shots.
Alright that's essentially all they're doing.
Okay, I'll remind you that they have not won a title yet.
I know, but that's where I would put my money.
Okay, advice from Malcolm Gladwell,
put your money on Houston. Yes, Houston.
It's an absolute pleasure, thanks so much for coming by.
Thank you, David.

redpajama_set_name: RedPajamaCommonCrawl


paying attention to salaries and benefits.
Our 2019 salary survey looks at pay grades across different sectors for a range of common job titles. The guides are arranged by function and location to give you the best results.
in line for a pay rise?
Randstad's salary and benefits 2019 guide offers key information on what to expect during the post-Brexit market, key findings with the financial services market and expected pay rises.
As it stands very little is known about what a Brexit deal will look like and if there's one thing businesses don't like it's uncertainty. However, one thing is certain: financial services is a resilient sector and remains the UK's biggest source of export and tax revenues. Our 2019 salary survey is coming soon.
Alison Starmer, MD, Client Solutions.


Moving lower for the 3rd day in a row, MAA finished Tuesday at 106.58 tanking $3.35 (-3.05%), strongly underperforming the S&P 500 (0.05%). This is the biggest single-day loss in over three months. Today's close at 106.58 marks the lowest recorded closing price since March 20th. The bears were in full control today, moving the market lower throughout the whole session. Closing below Monday's low at 109.48, the market confirmed its breakout through the previous session low after trading up to $3.18 below it intraday.
Tuesday's trading range has been $3.70 (3.37%), that's far above the last trading month's daily average range of $1.47. Weekly volatility is also higher, being way above the market's average weekly trading range. The longer-term, monthly volatility is currently slightly lower than usual for MAA.
After trading as low as 106.30 during the day, Mid-America Apartment found support at the 50-day moving average at 106.41. The share closed below the 20-day moving average at 109.08 for the first time since March 1st.
Crossing below the lower Bollinger Band for the first time since December 24, 2018, prices have shown unusually strong downward momentum in the short-term. This could either indicate a potential selling climax after which prices might head back up towards the mean of the Bollinger Bands at 109.08 or signal the beginning of a strong momentum breakout leading to even lower prices. The last time prices broke out below the lower Bollinger Band on December 24, 2018, MAA actually gained 3.29% on the following trading day.
Though the stock is currently in a short-term downtrend, this could just be a correction, as both the medium and long-term trends are still bullish.
Among the 14 market conditions that our pattern recognition engine identified today, the statistics for the Price Action based market condition "3 Consecutive Lower Closes" stand out. While it is usually interpreted as bearish, it has actually shown to be bullish for Mid-America Apartment. Out of 130 times, MAA closed higher 55.38% of the time on the next trading day after the market condition occurred. The optimal exit for swing trading this condition on the long side has been after 10 trading days, showing a win rate of 61.54% with an average market move of 0.70%.
Find out what happened when Mid-America Apartment Communities Inc. traded like this in the past. See the odds for each technical pattern with expected gain and loss.


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World AIDS Day: Stepping up the search for a cure
New funding from Gates Foundation and NIH give vote of confidence for an audacious goal
November 27, 2019 • By Sabin Russell / Fred Hutch News Service
The Seattle-based Bill & Melinda Gates Foundation (headquarters above) and the National Institutes of Health will invest a combined $200 million in gene-based cure research for HIV and sickle cell disease. Photo by Robert Hood / Fred Hutch News Service
As people around the globe prepare to mark World AIDS Day this Sunday, nearly 38 million men, women and children are living with HIV/AIDS, a disease that still has no cure.
Thankfully, at least 24 million of them, in nations rich and poor, are keeping the AIDS virus at bay with anti-HIV drugs; but the pills must be taken daily, for a lifetime. If the pills are stopped, the infection springs right back.
However, with philanthropic and government support, scientists at Seattle's Fred Hutchinson Cancer Research Center are working the long game. In addition to developing and testing HIV vaccines, they play a leading role in an expanding global effort to find a true cure, where the virus is stopped without the constant need for antiviral drugs.
That cure research — still a niche field in the universe of AIDS studies — relies on the notion that HIV can eventually be scrubbed out of the bodies of infected people by giving their blood cells protective genes, and that this gene therapy can one day be delivered to millions of people through just a shot in the arm.
On Oct. 23, these researchers received a significant vote of confidence when the National Institutes of Health and the Bill & Melinda Gates Foundation announced a plan to each provide $100 million in grants that will support gene-based research on cures for HIV as well as sickle cell disease, both of which are especially prevalent in resource-poor regions of Africa.
The Hutch researchers hope to win some of those grants to expand and further develop their efforts to harness the human immune system to fight HIV and sickle cell disease. The grants will be distributed over the next four years, with the hope of moving into clinical trials for such therapies in the next seven to 10 years.
Dr. Mike McCune is senior adviser for Global Health at the Bill & Melinda Gates Foundation. Photo by Robert Hood / Fred Hutch News Service
"Two hundred million dollars is a lot of money," said Fred Hutch virologist Dr. Keith Jerome. "There is no way to phrase that in any other way." Jerome and his Hutch colleague Dr. Hans-Peter Kiem are co-directors of defeatHIV, a collaborative of researchers from many institutions that since 2011 has been developing cellular and gene-therapy cures for the disease.
"One of the wonderful things about that number is that it is enough to get the attention of the scientific community at large. What you want to do is get the attention of people who have the knowledge and ability to solve the problem," Jerome said.
An initial focus on sickle cell disease
Dr. Mike McCune, senior adviser for Global Health at the Gates Foundation, said the focus of the collaboration with the NIH will be on finding ways to deliver cures for sickle cell disease or HIV in a practical manner — even by a single shot in a walk-in clinic — without the cost and toxicity associated with hospital-based gene therapy. "We want these interventions to be available to all, in all parts of the world, including resource-limited parts of sub-Saharan Africa," he said.
The NIH/Gates program will initially focus on sickle cell disease, where research on gene therapy has been going on longer and has advanced more quickly. Sickle cell disease arises from a genetic mutation that causes red blood cells to form in rigid crescent shapes that can bunch up, blocking blood flow and causing severe pain and anemia. It affects about 100,000 Americans — cutting life spans short by 20 to 30 years. It afflicts some 20 million people worldwide, most of them in Africa.
Preliminary results of human clinical trials for a gene therapy cure for sickle cell disease have been encouraging, and more results are expected shortly at the American Society of Hematology annual meeting Dec. 7–10 in Orlando.
"We are starting with sickle cell disease for two reasons: First, the burden of this disease in sub-Saharan Africa is enormous; secondly, we know precisely how to fix it genetically," McCune said.
Jerome agrees that a gene therapy cure for sickle cell disease is more likely to happen before one for HIV. "It is a difficult, difficult virus," he said.
Drs. Hans-Peter Kiem (left) and Keith Jerome are leading HIV-cure research at Fred Hutch Photos by Robert Hood / Fred Hutch News Service
Kiem, who holds the Stephanus Family Endowed Chair for Cell and Gene Therapy, is an oncologist who performs bone marrow and stem cell transplants on cancer patients. His HIV work is inspired in part by the case of Timothy Ray Brown, the Seattle native who, while living in Germany, became the first person in the world to be cured of HIV. He was saved by a blood stem cell transplant aimed primarily to cure his aggressive form of leukemia.
In 2007, Brown's doctors in Berlin found a stem cell donor who carried two copies of a mutated gene that confers natural resistance to HIV in about 1% of Caucasians in Europe. The mutation blocks the ability of HIV to break into cells through a kind of trap door on the surface of blood cells. The faulty genes essentially jam a component of that trap door, known as CCR5, so HIV cannot get in. Could that protection carry over in a transplant?
Inclusion is critical for HIV-cure research
As prospects improve for research on cures for HIV, advocates are urging that women and transgender people be included in any future clinical trials.
Women and girls make up roughly half of the 38 million people in the world living with HIV, but participation in clinical trials skews heavily toward males, said Brian Minalga, project manager for the Women's HIV Research Collaborative, a National Institutes of Health-funded advisory group housed at Fred Hutch.
"A cure would be huge. It would change everything, and women and transgender people need to be involved in that," Minalga said. "It is their human right."
At a recent conference of the Association of AIDS Care Nurses in Portland, Oregon, Minalga presented results of an analysis by the New York-based Treatment Action Group of 128 HIV-cure studies. Of the only 44 studies that reported enrollment by sex, 18 (40%) were all male, one was all female, and 25 included males and females.
"There's a problem here, systemically, about what research questions are asked and about how women and transgender people are enrolled," Minalga said. "Why does this matter? It is because men and women are different, and transgender and cisgender people (those whose gender identity matches the sex they were assigned at birth) are different."
The NIH Revitalization Act of 1993 requires that women and minority groups be included in all NIH-funded medical research, but the guidance only applies to late-stage clinical trials. As a result, Minalga said, females tend to be left out of early-stage studies, even in preclinical studies involving mice.
Brown and his doctors thought it would be worth a try. It was a brutal procedure that almost killed him, but he was cured of both HIV and leukemia. For more than a decade, he was the only person believed cured of HIV. This year, two more patients, in London and Dusseldorf, Germany, appear to have been cured with similar procedures.
Kiem and Jerome have co-hosted five scientific conferences in Seattle since 2014 to discuss research on ways to understand how and why Brown — and now two others — were cured by transplants, and how more cures could follow. The successful transplants essentially swapped out the patients' immune systems for new, HIV-resistant ones. The long-term goal is to expand and vastly simplify the process of modifying the human immune system without transplantation by transferring genetic traits that block HIV or command immune cells to destroy other cells where HIV quietly hides.
In current gene therapy experiments, a patient's own blood stem cells are removed and genetically modified ex vivo — outside the body — in a laboratory setting. Snippets of DNA that confer resistance to HIV, such as the CCR5 mutation, are inserted into genes of the patient's cells. This is a cut-and-paste process called gene editing, which is made possible by new generations of precision gene-cutting tools, such as the enzyme CRISPR/Cas9. The edited stem cells are then returned to the patient.
'Gene therapy in a syringe'
Blood stem cells are the mother cells of the immune system, and when these modified cells divide, their HIV-resistance genes are passed down to their progeny: a whole family of diverse blood cells, including the T cells that HIV normally likes to infect. Kiem said he and his colleagues are currently studying how to modify stem cells so they are not only resistant to HIV but also generate immune cells that can seek out and destroy any remaining infected cells in the patient.
Kiem is taking this curative process one big step further. A mixture containing all the ingredients for gene transfer — DNA and the gene-editing enzymes — is packaged into a syringe and injected into the body. The gene-transfer process takes place "in vivo," or inside the body. He calls it "gene therapy in a syringe." It has the potential to be safe, effective and relatively inexpensive.
Dismissed as "pie in the sky" by some leading HIV researchers, the approach has nevertheless inspired a cadre of scientists who see a path forward and continue to carry out studies aimed at overcoming the many barriers that remain.
McCune said the new grants are designed to answer questions addressing those challenges. Among them:
What type of microscopic vectors, or vehicles, can be used to ferry genes to blood cells? Options include hollowed-out viruses, gold nanoparticles or engineered protein cages.
What sort of ingredients — including gene-editing enzymes — should be carried by those vectors?
Can these vectors and their cargo be delivered safely and efficiently, without toxic side effects?
How many cells need to be modified for the cures to be effective?
"I don't think it is pie in the sky at all," Kiem said. The technique has been shown to be effective in early preclinical studies, and within the five to 10 years of the new grants, he believes it will have been tested in humans.
"The same thing we can do now ex vivo, we know we can do in vivo," he said. "It will be a process of fine-tuning."
Kiem recently described his vision for bringing an HIV cure to the poorest corners of the world at TEDxSeattle. He said that the research on HIV reminds him of what drew him to Fred Hutch a quarter century ago, when Dr. E. Donnall Thomas was challenging conventional wisdom with his belief that bone marrow transplants could cure cancer. Thomas in 1990 won the Nobel Prize in physiology or medicine for that work.
Now, Kiem sees in gene therapy an unconventional path to an HIV cure. "I want to focus on making this in vivo gene therapy work," he said, "so it can cure diseases like HIV/AIDS, sickle cell disease and even cancer."
Sabin Russell is a staff writer at Fred Hutchinson Cancer Research Center. For two decades he covered medical science, global health and health care economics for the San Francisco Chronicle, and wrote extensively about infectious diseases, including HIV/AIDS. He was a Knight Science Journalism Fellow at MIT, and a freelance writer for the New York Times and Health Affairs. Reach him at srussell@fredhutch.org.
Are you interested in reprinting or republishing this story? Be our guest! We want to help connect people with the information they need. We just ask that you link back to the original article, preserve the author's byline and refrain from making edits that alter the original context. Questions? Email us at communications@fredhutch.org
Vaccine and Infectious Disease
Hans-Peter Kiem
Keith Jerome
defeatHIV
Timothy Ray Brown
NIH grant
Scientists gather in Seattle to share strategies for an HIV cure Workshop focuses on ways to lower cost, broaden reach of gene therapy August 28, 2019
London transplant doctors report a second person likely cured of HIV 12 years after Timothy Ray Brown was cured, we have another March 5, 2019
Gene editing holds promise for shrinking HIV 'reservoir' Study mimicking Timothy Ray Brown's HIV-resistant mutation led to fewer latently infected cells — a key step toward driving the virus into remission without the need for antivirals April 25, 2018
Last Modified, December 09, 2019


pick Up time at 0800am driver /guide Will Be waiting at The Cruise ship Gang way holding a name sign and drive directly To Rome city first stop Colosseum tickets can Be bought online www.coopculture.it tour The Colosseum and furom next stop st peters and The Vatican a private guided tour inside The Vatican museum and Sistine Chapel. Tickets bought online www.museivaticani.va. Only €20 per Person for The vatican museum and sistine Chapel. Ticket time After The colosseum stop for Lunch, & free Time Then onto The vatican for 1300. With a private guided tour in The vatican and st peters.
Rtn back To The Port in civitavecchia for 1700.


The best bathroom design can be summed up into one word. Opinion. Everyone has their own style and the word best is very subjective. However, these bathroom designs are ones that everyone can take inspiration from and make it your own and have your very own best bathroom design. All it takes is your style and of course your budget. Check out our blog on 5 Simple Bathroom Storage Solutions and 5 Nifty Bathroom Storage Ideas for great ideas on how to save money and to save space.
This very modern bathroom is more than just a place to take a shower or use the toilet. No, this modern bathroom is a place you can go to relax and start/end your day in peace. The simple lines and simple décor makes this room a very balanced Zen-like-feel.
This bathroom is perfect if you don't have that much space in your bathroom. The color theme is simple and there is a sleek yet luxurious fill to this bathroom. If you want your bathroom with some sleek fixtures and warm tone with bronze, gold, and black then this is your best bathroom design. The shine from the gold adds an extra pop to the shower tiles and backslash to your walls.
Even if you're nowhere near the coast, this bathroom design is perfect for those ocean lovers. The turquoise and aquamarine colors are soft enough to not be shouting but bright enough to give you a elegant bathroom design. Make this your own by adding different shells and different shades of either coral, turquoise, or aquamarine.
This bathroom design strives from having an accent color. The beauty of it is that the accent color can be your favorite color. Adding towels with that matches the wall color also adds another layer to the simple yet perfect bathroom design. All you truly need is a bucket of paint that is your favorite color (and white if your bathroom is painted a color you don't like or if it needs touch-ups) and then you have a bathroom design that is pleasing to your eyes and its simple.
Having a simple solid color walls aren't the best way to have any bathroom designs that you will love. Luckily there is the accent wall that you can always count one! Accent walls involve a similar color as your solid color walls, but they also incorporate a design. Your design can be simple or complex. This accent wall has splashes of yellow with simple geometric line work. Your accent wall can be just simple wall paper. So, pick your design and your color for an easy yet chic design.


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Playson Casinos
Accepted countries
1 Playson Casinos
2 About Playson
3 Playson's Products
4 Special Features
5 Top Online Slot Games
6 Supported Platforms
7 Known Problems/Issues
8 Summing Up
Although we can't claim to have our eyes on every single online gaming company that has popped up in the last couple of years, we'll always have enough space for the more interesting ones – and Playson undoubtedly belong to that group.
About Playson
Playson are one of the newest faces on the online casino gaming scene, having been around only since the year of 2012. That doesn't mean that they're inexperienced, however, as they do have some veterans among their ranks.
What's more, they've risen so quickly that they simply have to be doing something well – and the good news is that their reputation has been rising at the same pace as their size and turnover.
The company has always been headquartered in Malta, although it's active all over the world and that country isn't the only place in which you can find its offices. You can visit their site at https://playson.com/.
Playson's Products
The online gaming scene might be littered with companies that have their attention spread across many different fields, but Playson are focusing on slots games to keep things as straightforward as possible.
At the time of writing, they were trying to expand their slots repertoire in order to be able to compete with at least some of the bigger games developers – and this focused approach is bound to win them a lot of fans. We fully understand the reasons behind many companies doing work on several fronts, but it's always nice to see someone who's all about delivering great gaming experiences.
In order to be absolutely honest here, we have to say that Playson have never belonged to the most creative of companies and that they are yet to come up with innovative features they could call their own.
That said, there are two things that we'd like to mention in connection with the company, the first of which is how consistent it is across the board as far as its slots are concerned. Whereas many developers have unbalanced repertoires that feature both top-notch and completely average games, there are virtually no bad apples in what the Playson arsenal offers right now.
Secondly, Playson seem to be very keen on making their slots rather stylish, which is especially evident when one takes a closer look at the interfaces of the games they've released in recent times. All of them are designed in a way that complements the theme of the given slot, which naturally makes for a more immersive experience.
Top Online Slot Games
The games repertoire Playson have is still rather small, but that doesn't mean that there aren't any games to recommend.
For starters, there's the atmospheric Aquatica slot that allows players to just sit back and enjoy exploring the world's seas and oceans. To be fair, some players won't like the somewhat simplistic gameplay, but the atmosphere is the game's main selling point – and we're sure that many will fall in love with it.
Secondly, we would like to draw your attention to Gold Rush, which will send you into the depths of a mine that's filled not only with gold, but also with hidden traps and treacherous moles. The theme is really interesting and so is the gameplay, so don't forget to take this slot out for a couple of spins.
Finally, there's also the Sky Way slot, which is the direct opposite of Gold Rush as far as the theme is concerned. Instead of exploring the depths of a mine, you'll be flying in a plane – and to call this a welcome change of tone would be an understatement. Sky Way is pacy and it has enough gameplay features (including free spins) to keep you interested for quite a while.
As a modern online gaming company, Playson have to be keeping an eye on the latest technologies – and the good news is that they seem to be doing exactly that, as they've got a big chunk of their repertoire available in both Flash and HTML5.
The latter is most certainly more relevant in connection with mobile platforms, but we quite like the fact that Playson haven't abandoned Flash just yet, as it means that they can offer their services to a broader variety of operators.
On top of that, it also gives more meaning to their claims of being able to build custom slot games that match the customer's brand and objectives – while many online casinos are now starting to turn towards the mobile sector, there are still quite a few that are more about the desktop experience.
Known Problems/Issues
Although we haven't been able to find any scandals or information that would make us doubt Playson's reputation, we have to say that we're quite surprised by the company's inability to get its games to the most prestigious of online casinos. We naturally wouldn't want to claim that it's easy to succeed in such a competitive environment, but it seems to us that it shouldn't be all that hard to make a deal with at least one or two of the biggest players.
Is there anything players should take away from this? Probably not, but it does give everyone grounds for questioning the skills of Playson's business department. We can only hope that they are going to improve big time on this particular front, as it would be a shame to see them struggle because of this.
We have yet to find a UK casino with a five pound deposit limit using Playson games.
When everything is put together, it seems to us that the near future will be absolutely crucial for Playson. They certainly have what it takes to become a mid-range games developer, but they will need to sign some big deals and prove that they can swim with the sharks.
More Casino Software Producers
Playson Slots
Sky Way Slot


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Precarious Climate
Bust the budget
Anti-politics
Targets Review
Liberals election policies 2013
Doha climate talks 2012
It's time to stop saying yes
Durban climate talks 2011
Why the Global Warming Contrarians Are Wrong
2010 Global Temperature Watch
Climate ignored in Australian federal budget
No setback for coal port expansion
Don't mention the warming
By James Wight in Carbon Price, Clean Energy Future, Climate, Climate Politics, News, Politics, Spin
The Gillard Labor Government's stupidity has reached a new low. They have released a new set of climate change ads… which fail to mention climate change. Instead they tell us about the Government's "Household Assistance Package":
Assistance for what, you could be forgiven for asking? You wouldn't know it, but in fact the ad is referring to household compensation for a $23 per tonne carbon price which will come into effect in July.
The Sydney Morning Herald described it as a "hard sell", in which case I'd like to see what a soft sell would look like. The ads explain that money will appear in Australians' bank accounts, as if we wouldn't notice it otherwise. They are run not by the Department of Climate Change but by the Department of Families and Community Services, and do not contain the words "climate", "warming", "greenhouse", "carbon", "pollution", "fossil fuel", "renewable", "carbon price", "carbon tax", or "clean energy". This is reportedly because focus groups concluded the word "carbon" turned off voters – but how do they know it's the word turning people off, and not the way they're using it?
I cannot overstate the irresponsibility of ignoring climate change. Global warming is not just another issue; it is an urgent threat to human civilization. And a recent overseas study concluded "media coverage of climate change and elite cues from politicians and advocacy groups are among the most prominent drivers of the [US] public perception of the threat associated with climate change". A government who fails to talk about the scientific basis for action on climate change is implicitly telling the public it is not a serious problem.
The Government is also shooting itself in the foot: how can you sell a policy without mentioning its fundamental reason for being? Voters reasonably suspect compensation will counteract the very purpose of the policy. By not mentioning climate, the Government is allowing the Opposition to frame the issue. The Liberal Party, whose headline policy is to repeal the carbon tax, will continue talking about it whatever the Government says. They have already described the ads as a "con" for advertising compensation without saying what it's for.
In one way I agree with the Liberals: these ads are a waste of $14 million. The Government should tell its market researchers to get lost, and write a new ad which explains we are facing a global climate crisis which requires urgent action.
Australia, Australian Labor Party, Carbon Tax, Climate Change, Communication, Environment, Global Warming, News, Politics, Thoughts
Watching the Deniers on 24 July 2012 at 21:30
It's like some tame, market-focus tested campaign for… what I can't say. It's tantamount to saying "Here, here's some cash".
The great disconnect between is explaining the price on carbon, the science and intended benefits.
What is lacking is TV/movie/web series trying to explain the science to the public form an Australian point of view. Instead, its been left to the media (recall 75% of print is News Ltd) to educate the public.
What is needed is plain, simple honesty explained in a compelling manner. The above ad is insulting, as the audience knows about he tax and is intelligent enough to understand what is *not* being said.
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OhioLINK Resources
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Citations for journal articles, monographs, theses, patents, software, audio-visual materials, and technical reports related to agriculture.
provides citations to journal articles, monographs, theses, patents, software, audio-visual materials, and technical reports. The records describe publications and resources encompassing all aspects of agriculture and allied disciplines including plant and animal sciences, forestry, entomology, soil and water resources, agricultural economics, agricultural engineering, agricultural products, alternative farming practices, and food and nutrition. Auxiliary subjects that support NAL's Information Center activities, such as agricultural trade and marketing, rural information, and animal welfare are also included in the database. Some institutions use a web-based citation manager called RefWorks. For help, check with your library staff.
AGRICOLA Off Campus Access
Index, abstracts and full text of articles on environmental studies.
covers applicable areas of agriculture, ecosystem ecology, energy, natural resources, marine & freshwater science, geography, pollution & waste management, environmental technology, environmental law, public policy, social impacts, urban planning, and more. Environment Complete contains citations for articles from 1,200 domestic and international journals, as well as 100 monographs. The database provides full text for many of the most used journals in the discipline, and for the conference papers of the North American Association of Environmental Education.
Environment Complete Off Campus Access
Garden, Landscape & Horticulture Index
Index and abstracts for articles about plants and gardens.
is a resource for access to articles about gardens and plants. Topics include horticulture, botany, garden and landscape design & history, ecology, plant and garden conservation, garden management, and horticultural therapy. A highlight of the database is its focus on environmentally sustainable horticultural and design practices. This index is designed for gardening enthusiasts, professionals, and students of horticulture and of garden and landscape design & history. Garden, Landscape & Horticulture Index covers general gardening serials of national, international, and regional interest, and serials devoted to specialty gardens and plant groups, most published in English.
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tends to adhere better than wet. Firmly press the fruit on inside of the glass and pour in the bottom layer. The trick to layered smoothies is to freeze the bottom layer for 15-20 minutes, then add the top layer.
If you want extra protein, add a packet of powder to either bottom or top layers. It's a quick, healthy way to start the day.


text:
11+ readers
My So-Called Afterlife
Written by Tamsyn Murray
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LoveReading View on My So-Called Afterlife
Highly Commended for the Teenage Book Prize 2010. A wonderful debut novel which, as well as being laugh-out-loud funny, is full of insights, compassion, and love. Fifteen-year-old Lucy has been stuck in the men's loo ever since she was murdered there six months ago. No one has been able to see or hear her – until Jeremy. Just her luck that he's a seriously uncool geography teacher-type! But Jeremy is determined to help Lucy. He finds out how she can leave her 'home' – albeit only temporarily – and meet other teenage ghosts, including the gorgeous Ryan. Jeremy is also determined to help her find her killer so she can find peace at last...
My So-Called Afterlife Synopsis
My So-Called Afterlife by Tamsyn Murray
My So-Called Afterlife Press Reviews
'Murray is someone to watch. Her novel drives along with great gusto. There's plenty of fun to balance loss. It's boy meets girl but so refreshingly different.' Teenage Reading Preview
Publisher: Piccadilly Press Ltd
Publication date: 26th February 2010
Author: Tamsyn Murray
Suitable for: 11+ readers, 13+ readers
Recommendations: Debuts of the Month
About Tamsyn Murray
Tamsyn Murray is the author of the hilarious Completely Cassidy series, in which eleven-year-old Cassidy is searching for her special talent. Tamsyn's special talents include performing onstage, being able to lick her own elbow, and writing many books for young readers, including the Stunt Bunny series, and Tanglewood Animal Park. Tamsyn lives in Hertfordshire with her daughter, her son, five rabbits, one dog, one cat and one husband.
More About Tamsyn Murray
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"Wanderlust" is a travel retail shop that aims to guide and document the adventures of non-mainstream travelers. The branding of "Wanderlust" was inspired by the magical patterns of the kaleidoscope in an attempt to recapture the serendipitous and fascinating experience of traveling.
"Wanderlust" features a unique publication that works as a travelogue/ travel guide. It accompanies the traveler on different occasions. Prior to the trip, the traveler has the chance to use it as a planner. It also suggests local experiences for the traveler during the journey. The publication remains useful after the trip as it offers space for memories and souvenirs.


L&D Radio has been on the airwaves for 50 years, broadcasting 24/7 to keep Luton & Dunstable Hospital patients comforted, entertained and informed.
It's run entirely by volunteers and now it's looking for more.
Communication manager Barbara Gray said: "Training is given because so many skills are required to run the station.
"These include broadcasting, technical, administration, communication, fundraising, ward visiting and many more.
The station – a registered charity – broadcasts a mix of music, entertainment, chat programmes, news and weather with an emphasis on the hospital and surrounding area.
The team visits wards to chat to patients, incorporating their experience into the community service radio station.
VIP guests have included well-known personalities such as Chris Tarrant, Esther Rantzen, David Pleat and Marty Wilde.
National and international news is broadcast on the our, every hour.
And when the studio isn't manned, a computer system relays easy-listening music.


Rosie here to share a couple of cards using the fabulous Tim Holtz 3D embossing folders 😁.
I took a piece of Ranger watercolour paper, misted with water and ran through my Big Shot 3x, below is the result after inking with Distress Oxide Cracked Pistachio ink.
I applied the ink with a Nuvo Blender brush which can be special ordered from Scrap Shotz.
After applying Distress Oxide Ink to the leaves and flowers I added Distress Crayons directly to the flowers and some of the leaves, blending them out with water and my finger.
Another look at the inked panel.
I used some products from a prior Scrap Shotz kit.
Misted these flowers with Antiqued Bronze Distress Mica Spray.
This flower is die cut with the Tim Holtz Tattered Floral die from Scrap Shotz kit papers and then embellished with a Tim Holtz Gumdrop Heart.
The watercolour card stock was embossed in the same manner as above, misting the panel and then running through the Big Shot 3 times.
I then applied Iced Spruce Distress Oxide Ink with a Nuvo Blender Brush all over the embossed card stock.
Blended Distress Crayons in Hickory Smoke, Walnut Ink and Black Soot.
Misted embossed panel with Brushed Pewter Distress Mica Stray, then created sentiment from a Scrap Shotz kit and finished off with a few Studio Katia Black Onyx crystals.
There are lots of great products available at Scrap Shotz , click on the link to check out what's available!


The SAP Mission The Student Assistance Program recognizes that personal problems are part of life. In today's society our students are often subjected to personal issues that may hinder their ability to become academically successful. Our mission is to support our students and their families through all of their difficulties, and provide the appropriate services and resources needed to make them successful.
About Me This is my 21st year as SAP Coordinator at North High/North Iredell Middle. Prior to becoming a Raider/Bear, I worked in the mental health system for 10 years as an adolescent substance abuse professional. I am a honor graduate from Appalachian State University with a Bachelor of Science Degree in Social Work. I am a Licensed School Social Worker.
I love the beach, music, concerts, movies, sports, especially ECU, UNC, Carolina Panthers and Boston Red Sox! I believe God, family, friends, and laughter are the best kinds of medicine!


The computer I use for editing and publishing The Kids' Bulletin is dying and I don't have money right now to upgrade. I really don't like asking for donations, but if you or someone you know has a working laptop they don't need it would be a huge help. The computer I have now is a 10+ year old Apple MacBook, so a newer MacBook would be the smoothest to upgrade to, but any laptop that can handle some graphics would do.
UPDATE: I have received a number of generous donations and was able to buy a refurbished MacBook. Thank you to all who contributed!
I just sent you some (Canadian) money through PayPal. If you've never used PayPal before, you'll receive an email from them explaining how to open your account, and then transfer the balance to your bank account.
PayPal is very safe and extremely secure — you shouldn't worry about revealing any of your bank details to them. Their reputation depends on their ability to guard their customers' details carefully; they have never been subject to any kind of hacking or breach.
of St Bernadette Ajax Ontario …..
Where are you please ?
Thank you, Thomas! There's a paypal donation button on the website if that works for you, or if you prefer another method just send me an email at thekidsbulletin@gmail.com and we can figure something out. Thank you in advance for helping share the Faith! God bless!
I am not sure where you are located but we have a program through one of our service groups, Alhambra, and supply refurbished computers and laptops that come from the University of Western Ontario. We have lots! I will forward your email to the fellow who looks after this and he can get in touch with you too.
Thank you! Yes, that would definitely help! God bless!
Sometime come visit my ministry at http://www.youturns.org.
Thank you so much, Rosy! Your gift will definitely help!


I was approached by the author some time ago with the question if I wanted to read his thriller novella. Although I don't read a lot of novellas in general, the summary caught my attention and I decided to give Lemon Sting a go. And I have to say that this novella has pleasantly surprised me. For its length, the main characters are surprisingly well developed as well as the general plot itself. The story is both fast-paced, entertaining and packed with intense action scenes and plot twists that will keep you on the edge of your seat. Lemon Sting has a lot of different POVs for a novella, but they are well executed and didn't distract from the plot. In fact, the prose in general is easy to read and I can definitely recommend this novella to anyone who enjoys a good action-packed crime thriller.
Both Margaret and Lee seem to be trapped in a daily routine that never seems to end; her working at a restaurant and living life day by day, him working at an old electronics store and bored out of his mind most of the time. When Margaret breaks her routine one night and goes clubbing, she ends up too drunk to function at her neighbor Lee's apartment. She doesn't remember much about the night before, but it seems like her past has finally caught up with her… And Lee is dragged into the mess along with her. Things will soon spiral further out of control; will they be able to find a way out?
If you are looking for a fast-paced, action-packed and entertaining thriller novella, Lemon Sting is definitely a great choice. It reads almost like an action movie and both plot and characters are well developed, especially since we are talking about a short novella. This debut is without doubt very promising!


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Timmy Kent: The plug and play
99 spotlight, Year in Review
Tim celebrates with the rest of his first line after finding the twine
Tim wasn't with us from the start but his play on our first line was a huge factor in our 20 win season
Tim settles a rebound down before putting it top shelf
Traffic in front was no problem for Tim as he finds the puck in the back of the net
Tim joined us on November 7th and was plugged into the first line and looked like he was with us since main camp. Tim's hustle and heart was always shown on the ice, skating to every puck on every play and he wasn't afraid to show his physical side when it mattered. Timmy Kent's dominant performance on the first line saw him with 48 points, including 11 goals and 37 assists and averaged 1.3 points per game. Tim finished 3rd on our team in points right along with the rest of our first line, Tim had a very impressive 6 games with 3 points and in his last game finished on a high note tallying 4 assist. Tim's speed however isn't represented by a single stat, Tims speed was unmatched by opponents defenseman gaining him a lot of quality offensive chances and he capitalized whenever he was given space. Tim's play on the power play was shown when he tallied 4 power play goals, and was 2nd on the team on power play assist with 13. Tim was quickly noticed by the community as a player who was all heart and there was nobody who could slow him down or get in his way, we wish Tim the Best of Luck in the future!
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Good evening my dear crocheters. I hope you're having a nice day because right now we are going to teach you how to crochet arguably the best Mandala Doilies in different colors. I am almost sure you have never made something like this before and there is a chance these mandala doilies will become the most exciting project of your life. Of course I am not able to predict the future but if you decide to crochet them, you definitely will not be disappointed. At the first sight it might appear too difficult for you but we have brought to you very easy and helpful patterns with the step by step instructions, that will make your crocheting time much more enjoyable and entertaining. Our friendly blog wishes a best of luck to you with these lovely mandala doilies. Enjoy yourself and always feel free to share your experience and ideas with us and other crochet lovers.
How do I access these mandalas patterns?


History, culture, walkability! These are the features of Boston that local Olympics supporters are using to sell the city's bid for the 2024 Games.
I spoke with someone connected to the International Olympic Committee who told me that Boston has rocketed to the top of their consideration list because of how the city was able to shut itself down after the Boston Marathon bombing.
Greater Boston's shutdown the Friday following the Marathon bombings is a controversial topic, with competing perspectives on whether it was a public safety necessity or a chill on civil liberties. According to Zirin, though, it was a very good move for Boston's Olympics aspirations.
Zirin is citing a single anonymous source, so take it for what it's worth. The IOC did not respond to a request for comment from Boston.com. Security, to note, is always considered a key part in the host city selection process.
Regardless of whether the post-bombing response is affecting the evaluation of Boston's bid, security is a massive element—and cost—in the Olympic planning process. Security costs were greater than $1.5 billion for the London Summer Games in 2012, doubling the original projections, despite London already having fairly advanced security infrastructure.
A simple glance at the main Olympic Park in East London confirms this will be the most security-conscious Games in history: More than 11 miles of razor-wire-topped electric fencing separates the site from its surroundings, every entrance is guarded by soldiers and the surrounding streets and shopping malls are patrolled by police carrying 9mm semi-automatic weapons–an unusual sight in Britain, where armed patrols are normally found only at airports.
The Boston 2024 group has estimated that the bid could be supported with $4.5 billion in privately-funded construction costs and another $5 billion in publicly funded infrastructure costs. (Opponents of the bid have estimated a higher total cost figure.) There hasn't been much mention of a projected security price tag for the 2024 games, but "the federal government would be responsible for security costs,'' a Boston 2024 spokesperson told Boston.com. The event would all but certainly be designated as a National Special Security Event (as was another high-profile and high-security Boston event, the 2004 Democratic National Convention). Such events are coordinated and funded by the feds, with local and state aid available either in the form of grants or in specially-allocated money for some. The last Olympics held in the United States—the 2002 Salt Lake City Winter Games—was also a National Special Security Event, for which the federal goverment committed at least $225 million.
The safety of the Games is of primary importance and our security planning has always been focused on providing the most secure and welcoming Olympics for a global audience. Our plans for security include working with local, state and federal partners as we did for the Democratic National Convention in 2004, which was another National Special Security Event. Our top advisors on security, (former Massachusetts Homeland Security Undersecretary) Juliette Kayem and (former Boston Police Commissioner) Ed Davis, will continue to be on hand as we develop our plans. As we continue to move forward, we will work with all our partners, recognizing that security is fluid, risks will change and technology will give us greater opportunities. And we are always aware that the safety and security of the city and its residents, the athletes, and the visitors is our obligation.


Metallic nanowires (NWs) are the key performers for future micro/nanodevices. The controlled manoeuvring and integration of such nanoscale entities are essential requirements. Presented is a discussion of a fabrication approach that combines chemical etching and ion beam milling to fabricate metallic NWs. The shape modification of the metallic NWs using ion beam irradiation (bending towards the ion beam side) is investigated. The bending effect of the NWs is observed to be instantaneous and permanent. The ion beam-assisted shape manoeuvre of the metallic structures is studied in the light of ion-induced vacancy formation and reconfiguration of the damaged layers. The manipulation method can be used for fabricating structures of desired shapes and aligning structures at a large scale. The controlled bending method of the metallic NWs also provides an understanding of the strain formation process in nanoscale metals.
This paper is a postprint of a paper submitted to and accepted for publication in Micro and Nano Letters and is subject to Institution of Engineering and Technology Copyright. The copy of record is available at IET Digital Library.


I'm back! I gave up on trying to keep posts more or less chronological. Screw it.
We are still in Japan at the moment. Love it as always. How could we not.
I will start with a few posts from the lovely Canon Av-1. Don't remember what film this is since it has been in the camera a while.
These are all from our hometown Koenji.


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Korean J Radiol. 2017 Sep-Oct;18(5):821-827. doi: 10.3348/kjr.2017.18.5.821. Epub 2017 Jul 17.
Photoacoustic Imaging for Differential Diagnosis of Benign Polyps versus Malignant Polyps of the Gallbladder: A Preliminary Study.
Chae HD1, Lee JY1, Jang JY2, Chang JH3,4, Kang J5, Kang MJ2, Han JK1.
Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul 03080, Korea.
Division of Hepatobiliary-Pancreatic Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul 03080, Korea.
Sogang Institute of Advanced Technology, Sogang University, Seoul 04107, Korea.
Department of Biomedical Engineering, Sogang University, Seoul 04107, Korea.
Department of Electronic Engineering, Sogang University, Seoul 04107, Korea.
To investigate the feasibility of ex vivo multispectral photoacoustic (PA) imaging in differentiating cholesterol versus neoplastic polyps, and benign versus malignant polyps, of the gallbladder.
A total of 38 surgically confirmed gallbladder polyps (24 cholesterol polyps, 4 adenomas, and 10 adenocarcinomas) from 38 patients were prospectively included in this study. The surgical specimens were set on a gel pad immersed in a saline-filled container. The PA intensities of polyps were then measured, using two separate wavelength intervals (421-647 nm and 692-917 nm). Mann-Whitney U test was performed for the comparison of normalized PA intensities between the cholesterol and neoplastic polyps, and between the benign and malignant polyps. Kruskal-Wallis test was conducted for the comparison of normalized PA intensities among the cholesterol polyps, adenomas, and adenocarcinomas.
A significant difference was observed in the normalized PA intensities between the cholesterol and neoplastic polyps at 459 nm (median, 1.00 vs. 0.73; p = 0.032). Comparing the benign and malignant polyps, there were significant differences in the normalized PA intensities at 765 nm (median, 0.67 vs. 0.78; p = 0.013), 787 nm (median, 0.65 vs. 0.77; p = 0.034), and 853 nm (median, 0.59 vs. 0.85; p = 0.028). The comparison of the normalized PA intensities among cholesterol polyps, adenomas, and adenocarcinomas demonstrated marginally significant differences at 765 nm (median, 0.67 vs. 0.66 vs. 0.78, respectively; p = 0.049).
These preliminary results indicate that benign versus malignant gallbladder polyps might exhibit different spectral patterns on multispectral PA imaging.
Gallbladder neoplasm; Gallbladder polyp; Neoplastic polyp; Photoacoustic technique
10.3348/kjr.2017.18.5.821
Normalized PA intensities of cholesterol and neoplastic polyps.
Mean normalized PA intensities of cholesterol and neoplastic polyps (A) at shorter wavelengths between 421 and 647 nm, and (B) at longer wavelengths between 692 and 917 nm. Error bars denote standard deviation. Cholesterol polyps had significantly higher PA intensities at 459 nm compared to neoplastic polyps. PA = photoacoustic
Photoacoustic Imaging for Differential Diagnosis of Benign Polyps versus Malignant Polyps of the Gallbladder: A Preliminary Study
Korean J Radiol. 2017 Sep-Oct;18(5):821-827.
Normalized PA intensities of benign and malignant polyps.
Mean normalized PA intensities of benign and malignant polyps (A) at shorter wavelengths between 421 and 647 nm, and (B) at longer wavelengths between 692 and 917 nm. Error bars denote standard deviation. Malignant polyps had significantly higher PA intensities at 765, 787, and 853 nm compared to benign polyps.
Normalized PA intensities of cholesterol polyps, adenomas, and adenocarcinomas.
Mean normalized PA intensities of cholesterol polyps, adenomas, and adenocarcinomas (A) at shorter wavelengths between 421 and 647 nm, and (B) at longer wavelengths between 692 and 917 nm. Normalized PA intensities of adenocarcinomas were significantly higher than those of cholesterol polyps at 765 nm.
Gray-scale ultrasound images and normalized PA intensities of cholesterol polyp and adenocarcinoma.
A. GB cholesterol polyp (arrow) in 53-year-old woman. Gray-scale US exhibits hyperechoic polypoid mass (2.1 cm) in GB body. B. GB adenocarcinoma (arrow) in 45-year-old woman. Gray-scale US shows iso- to hyperechoic mass (2.3 cm) in GB body. C, D. Mean normalized PA intensities of two polyps (C) at shorter wavelengths between 421 and 647 nm, and (D) at longer wavelengths between 692 and 917 nm. Two polyps show distinct PA spectral patterns: PA intensity of cholesterol polyp continuously decreases at 692–917 nm, whereas adenocarcinoma exhibits absorption peak at 875 nm. GB = gallbladder, US = ultrasonography
Adenocarcinoma/diagnosis
Adenocarcinoma/pathology
Adenoma/diagnosis
Adenoma/pathology
Diagnosis, Differential
Gallbladder Diseases/diagnosis
Gallbladder Neoplasms/diagnosis*
Gallbladder Neoplasms/pathology
Photoacoustic Techniques*
Polyps/pathology*
Precancerous Conditions
The Korean Radiological Society
Gallbladder Cancer - MedlinePlus Health Information


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GOP's Health Bill Lowers Premiums - Why Democrats Won't Support It
The GOP proposed a new bill that could lower health insurance premiums by 40%, and provide additional funding for state and health insurers, but why aren't Democrats backing the bill?
By Agnus Smith
The GOP released a new healthcare that aims to both stabilize the health insurance marketplace and lower health insurance premiums. The Democrats are opposing the bill which includes language that would further restrict federal funding for abortions.
The health insurance marketplace was created under the Affordable Care Act and was intended to create a greater level of health equity in the US. However, since 2014, the health insurance marketplace has faced a backlash with the rising costs of premiums, along with major health insurance carriers pulling their plans.
In an attempt to create more competition, and ultimately drive costs down, President Trump has passed a few different pieces of legislation that have created uncertainty in the healthcare world. Legislation that includes eliminating the individual mandate, deregulating qualified health plans, and eliminating subsidies for health insurers.
Health insurance prices are expected to rise once again this year, and Senator Lamar Alexander, Senator Susan Collins, Representative Greg Walden, and Representative Ryan Costello, are looking to ease the burden.
What The New Healthcare Bill Proposes
Under the new healthcare bill, the government would allocate additional funds to both states and health insurers. The funds would be spread out over 3 years starting in 2019 and would provide subsidies for health insurance companies which would allow them to insure low-income members and $30 billion for states to provide coverage for residents with high medical costs.
Sponsors of the bill are hoping to get bipartisan support fast, so it can be included in the spending package Congress is expected to approve soon. President Trump was hoping to include legislation that would lower premiums in the spending package, which is why the bill was put together in the first place.
Why The Bill Doesn't Sit Well With Democrats
If additional healthcare funding was the only piece of legislation being proposed, the bill would probably have received bipartisan support. However, a spokesperson for Senator Patty Murray, the top Democrat on the Senate health committee, released the following statement:
"Senator Murray is disappointed that Republicans are rallying behind a new partisan bill that includes a last-minute, harmful restriction on abortion coverage for private insurance companies instead of working with Democrats to wrap up what have been bipartisan efforts to reduce health care costs."
Abortion has long been a dividing subject among Democrats and Republicans, and federal funding for the controversial procedure has set back healthcare talks for quite some time. Democrats and Republicans are still hoping to work a deal out that would benefit the American people.
If the new healthcare bill was added to the spending package, the CBO projects it will not add to the federal deficit, and it would lower the cost of premiums for individuals and families by 40%.


The Report is published today – Wednesday 16 January 2013! The link to see the Report is shown here: http://bit.ly/VkJLLP Please let me have your comments asap. I will write my own considered comments – both on what is in the Report and what is not – early next week on 25 January.


Go Baby Go is a community based non-profit program that provides modified ride-on cars for children with limited mobility. Currently, there are no commercially available power wheelchairs for children under the age of three. However over thirty years of research demonstrates the benefits of early powered mobility on a child's social, emotional, physical and cognitive development. Go Baby Go was designed to fulfill this need with low-cost and efficient means, providing cars with whatever personalized postural supports and modest electrical modifications that may be individualized as necessary.
Beginning at the University of Delaware under Dr. Cole Galloway, Go Baby Go has had tremendous success in creating sustainable branches all across the United States. Particular success has been found in Oregon, with branches in Corvallis and Portland co-lead by Dr. Sam Logan, PhD and Dr. Bethany Sloane, DPT. To expand the program further, our team will be travelling to rural and urban cities around China, a country in great need of more advancement in rehabilitative practices. Additionally, Go Baby Go has partnered with Glencoe High School's nationally renowned robotics team Shockwave to create an easily-adapted support system that can adjust to different children's needs with simple modification, catering to an environment such as an orphanage with numerous children in need of a car. We will also be providing education to therapists and practitioners about the importance of early mobility and benefits these cars can provide. We will be demonstrating and teaching how to adapt the cars themselves, along with providing translated manuals. Last, we will provide various orphanages that serve children with disabilities with our adapted cars. We hope to create an impactful and sustainable program abroad that will continue to develop and grow, changing the lives of numerous children.


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Students for Justice in Palestine
Students for Justice in Palestine (ASU Chapter)
#ASUDivest
Palestine Children's Relief Fund Benefit Concert ft. Invincible, Khaled M., Remi Kanazi, and Shining Soul
SJP ASU
Club Red/Red Owl
2155 E University Dr #112 Tempe, AZ 85281, AZ
Students for Justice in Palestine at ASU is honored to welcome hip hop artists and performing poets: Invincible, Khaled M., Remi Kanazi, and Shining Soul to share their talents in order to raise funds for Palestine Children's Relief Fund – Arizona Chapter.
Purchase tickets online here. At-the-door tickets will be limited.
Venue Website: www.clubredrocks.com
INVINCIBLE: A hip hop artist with wordplay and rhymes that will leave you speechless. Invincible's lyrics are like a Sledgehammer to the political and social constructs you once thought you knew. Invincible is based in Detroit, but their reach connects people from around the globe beginning with small communities.http://emergencemedia.org/invincible
KHALED M.: The son of a Libyan revolutionary, a Libyan-American hip hop artist and reigning Chicago Urban Music Awards "Lyricist of the Year" has been featured on CNN, ABC World News, Yahoo! News, BBC, Complex Magazine, NPR and more.http://thisiskhaledm.com/
REMI KANAZI: Palestinian-American poet and activist based in NYC. The editor of the anthology of hip hop, poetry and art, Poets for Palestine (2008), and the author of the collection of poetry, Poetic Injustice: Writings on Resistance and Palestine (2011). He has toured hundreds of venues across the US, Canada, Europe and the Middle East. http://poeticinjustice.net/
SHINING SOUL: A grass roots duo based out of PHX, originating from the occupied O'odham land of southern Arizona, Shining Soul's unique vintage means of beat production, and down to earth, empowering rhyme delivery is reminiscent of Hip-Hop's early days, when beats, rhymes, and community empowerment took priority.http://shiningsoul-music.blogspot.com/
PALESTINE CHILDREN'S RELIEF FUND (AZ Chapter): The Palestine Children's Relief Fund is a registered non-political, non-profit, 501(c)3 tax-exempt organization that was established in 1991 by concerned people in the U.S. to address the medical and humanitarian crisis facing Palestinian youths in the Middle East. It has since expanded to help suffering children from the region, based only on their medical needs. [They] do not discriminate based on religion, gender, nationality or sect.
http://www.pcrf.net/community/arizona/
https://www.facebook.com/AZPCRFChapter
Thank you to all volunteers and supporters currently making this possible: Students for Justice in Palestine, The Underground Foundation, Davina Kumar (flyer artwork), and Ellie Craze (flyer design).
THE UNDERGROUND FOUNDATION (TUF): TUF is an organization founded by ASU Students, inclusive to all, dedicated to solidifying and improving an independent music scene at Arizona State University and her surrounding cities. https://www.facebook.com/TUFASU
Link to the Facebook event
Link to SJP's Facebook page
A lecture by Max Blumenthal: "High on Zionism: The Indoctrination of Apartheid Israel Today"
Lecture by Fr. Bob Holmes and Mr. Amos Gvirtz


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ACQUISITIONS/MERGERS
PRIVACY STATEMENT MEDICAL DEVICE NEWS MAGAZINE
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Home CLINICAL TRIALS, STUDIES, REGISTRIES, DATA Neuromod Devices Publish Positive Results from Large Scale Tinnitus Clinical Trial
Neuromod Devices Publish Positive Results from Large Scale Tinnitus Clinical Trial
Study Represents the Largest and Longest Followed-up Clinical Trial Ever Conducted in the Tinnitus Field
Neuromod Devices Limited ("Neuromod"), the Irish medical device company specializing in the treatment of chronic tinnitus, commonly described as 'ringing in the ears', has published the results of the Company's TENT A1 (Treatment Evaluation of Neuromodulation for Tinnitus) clinical trial in this week's edition of Science Translational Medicine in a paper titled: 'Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical study'.
Neuromod notes the clinical trial was conducted between 2016 and 2019 and was designed to track changes in tinnitus symptom severity. The trial investigated the bimodal neuromodulation approach, using Neuromod's non-invasive stimulation device that delivers sound to the ears and electrical stimulation to the tongue.
The study represents the largest and longest followed-up clinical trial ever conducted in the tinnitus field with 326 enrolled participants, providing evidence regarding the safety, efficacy, and patient tolerability of bimodal neuromodulation for the treatment of tinnitus. 86.2% of treatment compliant participants reported an improvement in tinnitus symptom severity when evaluated after 12 weeks of treatment, with many experiencing sustained benefit 12 months post-treatment.
The study was conducted at the Wellcome Trust-HRB Clinical Research Facility, St. James's Hospital, Dublin, Ireland and the Tinnituszentrum of the University Regensburg, Germany. There were consistent therapeutic outcomes across both clinical sites, with no SAEs Serious Adverse Events (SAEs related to the treatment and a high satisfaction rate across a large cohort of participants. A Medical Research Organization (NAMSA, Minneapolis, Minnesota, USA) guided and assisted the close-out process of Neuromod's clinical trial.
The tinnitus treatment device, now branded as Lenire®, which was used in the study was developed by Neuromod and consists of wireless (Bluetooth®) headphones that deliver sequences of audio tones layered with wideband noise to both ears, combined with electrical stimulation pulses delivered to 32 electrodes on the tip of the tongue by a proprietary device trademarked as Tonguetip®. The timing, intensity, and delivery of the stimuli are controlled by an easy to use a handheld controller that each participant is trained to use. Before using the treatment for the first time, the device is configured to the patient's hearing profile and optimized to the patient's sensitivity level for tongue stimulation.
For the trial, participants were instructed to use the Lenire® device for 60 minutes daily for 12 weeks. Out of 326 enrolled participants, 83.7% used the device at or above the minimum compliance level of 36 hours over the 12-week treatment period. For the primary endpoints, participants achieved a statistically and clinically significant reduction in tinnitus symptom severity.
When treatment was completed, participants returned their device and were assessed at three follow-up visits up to 12 months. 66.5% of participants who filled out the exit survey (n=272) affirmed they had benefited from using the device and 77.8% (n=270) said they would recommend the treatment for other people with tinnitus.
Participants in the study were screened and selected based on a pre-defined list of inclusion and exclusion criteria to ensure the trial had a wide distribution sample of the tinnitus population. More information on the criteria can be found on https://www.clinicaltrials.gov/ using the identifier NCT02669069 and the full paper can be accessed here: https://www.neuromoddevices.com/tenta1results
Dr. Ross O'Neill, Founding CEO of Neuromod commented: "We are delighted to announce the publication of positive results from our TENT-A1 clinical trial, which has shown significant improvements in tinnitus symptoms in patients using our unique Lenire® device. There is a globally recognized clinical need for evidence-based treatments for tinnitus, such as Lenire®, due to the lack of effective options for this debilitating condition. Neuromod is proud to be at the cutting edge of efforts to research and develop new solutions that can contribute to solving this chronic condition that affects 10-15% of the population worldwide. We are committed to continuing our research in the field and to advance our unique chronic tinnitus treatment technology".
Hubert Lim, Chief Scientific Officer of Neuromod commented: "I am truly proud of our Company's ability to perform such a large-scale randomized clinical trial in two countries, enrolling 326 participants to demonstrate the safety and efficacy of a new solution for tinnitus. This study tracked the post-treatment therapeutic effects for 12 months, which is a first for the tinnitus field in evaluating the long-term outcomes of a medical device approach. The outcomes are very exciting and I look forward to continuing our work to develop a bimodal neuromodulation treatment to help as many tinnitus sufferers as possible."
SOURCENeuromod Devices Limited
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The M3F (McDowell Mountain Music Festival) is the all non-profit event for musical festivals. It was established in 2004 but it has become much famous than any other festival and it seems to be the final destination for the festival goers. The Festival has attracted visitors to Arizona with previous acts such as Flume, Beck, Kid Cudi, Chromeo, Father John Misty, Grouplove, The Avett Brothers, The Revivalists, DJ Mustard, The Roots, The Shins, Slightly Stoopid, and many others who were interested in it with real meaning.
With a promise to giving back, M3F has adopted a 3 C's belief – community, culture, and charity. These 3C's fuel the Festival's underlying dedication to its local people and causes. In the spirit of this belief, all of the proceeds from the Festival benefit local nonprofit organizations that are really needed to be funded. M3F is a great opportunity for all the people out there to experience the love and passion for the music and art while enthusiasm and power for helping the community. The foremost aim of the M3F (McDowell Mountain Music Festival) is to connect the community through a festival gathering including music, arts and food. The amazing environment for the entertainment of the people belongs to the different communities, companies and their employees. Secondly, its mission is to support the arts in an effort that they may grow and exist for future generations to enjoy and convert the same passion in the upcoming future generations. Also to provide financial support and education to family-based charities in an effort to provide equitable advancement throughout the community to make this world and society a better place to live. M3F was built on the idea of giving back. This is why they do and what they do. Since it started in 2004, M3F has donated over $1 Million dollars to local Arizona charities. In 2018, it donated $65,000 to local charities. They will continue to donate 100% of their proceeds to help local organizations reach their goals.
invisionAZ along with a number of Phoenix area sponsors presents this year's Arizona Tech Summit. As in years past the Tech Summit will welcome speakers from leading edge tech companies that are driving innovation in Arizona, as well as the investors who are powering today's most exciting start-ups. The goal for all attendee's is to expand their horizons, receive the right tools and make vital connections in the broad spectrum of ever-changing technology trends.
The featured speaker for 2019 is Dallas Maverick NBA owner, tech entrepreneur, and TV Show Shark Tank Star Mark Cuban. You can expect an update on Arizona's FinTech Sandbox.
APS, Arizona Chamber of Commerce, Arizona Chamber Foundation, CenturyLink, DLA Piper, GPEC, Keap, SRP, Thiel Capital, Arizona Commerce Authority, BlueCross BlueShield of Arizona, Trinity Capital Investment, University of Arizona, axialHealthcare, Arizona Diamondbacks, AZ Big Media, Chamber Business News, Lucid Agency, The Swedish-American Chamber of Commerce, Offerpad, Patron Media, and UBS.
invisionAZ was created to close the gaps in Arizona's vibrant tech ecosystem. At the First Annual AZ Tech Innovation Summit in March of 2017, leaders in the technology industry shared their insights on the strengths and weaknesses of Arizona's innovative ecosystem. The blueprint of invisionAZ was developed based on this dialogue and the organization was formed to transform the Valley into an attractive environment for entrepreneurs.
A collaborative group of business, civic, political, and venture capital leaders have come together to assemble a solutions-based plan to address these gaps. invisionAZ will provide Arizona's tech ecosystem with real solutions to further position the state as a leader in the new economy.
SynTech is not your average technology expo! It's leading-edge! It's Where Business Gets Done!
You can expect to see the newest technology you need to run your small business effectively and efficiently. Spend the day with us and leave re-charged and ready to take on 2019!
SynTech is the premier product demo event of the year connecting small business with current trends! Achieve synergy and connect with executives from every industry while learning from expert speakers at SynTech. You will leave with all the confidence you need to implement a plan that will improve your business and inspire your customers.
You can expect to see rising new talent & innovators, leaders in the technology industry, and all types of business owners. Attendees walking the floor at SynTech typically have one thing in common: a desire to learn how today's technology can improve their business and the success of their people.
Anything and everything to make you "tech savvy!" From advanced technologies in e-commerce to IT solutions; software to virtual reality; hardware to cybersecurity; cloud HR to mobile marketplace; we'll have it ALL.
Attendance is FREE with registration (limited time only), granting you access to hours of live product demos, speakers, career networking, food & drinks, and more!
Expose your company to small business!
ASBA member companies receive a special savings of up to $100 off exhibit space. Membership benefits also includes year-long marketing, advertising, and expert advisors. Contact Robin Duncan for more info.
Interested in being an Event Partner?
Connect your brand with 30K media hits, we offer the greatest innovations that relate to advanced technologies in Arizona. Contact Jodi Towns for more info.
Ken Colburn is the Founder and CEO of the Data Doctors family of companies that specialize in providing technology services to small businesses and busy consumers. For more than 20 years, Ken has been providing "tech advice to non-tech people" through video, radio and print with a focus on demystifying complicated technology issues for every day users.
- Vital Steps to Protect against ransomware attacks.
Join the Arizona Technology Council for its third annual MedTech Conference on Thursday, March 28, 2019 at Venue8600 in North Scottsdale. The MedTech Conference is bringing together healthcare innovators, influential policy-makers, and other healthcare service professionals committed to promoting and supporting the industry in a uniquely multifaceted environment designed to showcase Arizona's innovative medical technology. The MedTech Conference seeks to advance industry discussion from key perspectives through expert panel sessions, keynote speakers, and product exhibits to provide opportunities in education, business development, capital formation, and networking.
events@aztechcouncil.org for more information on sponsoring this great event.
NetworkingPhoenix is a leading business networking in the area, so you can expect great opportunities at their Signature Event.
What better time to learn about the best networking techniques than right before a networking event?
Discover how to effectively network at the Signature Event … How to be Memorable … What to Talk About … and More!
This is a FREE seminar! Get there early to meet & greet as well as grab a seat.
HUGE thank you to Gethner Education Coaching & Consulting for being our Title Sponsor! A presentation by Stuart Gethner will ensue.
Founded in 2008 by Gelie Akhenblit, NetworkingPhoenix.com is the Valley's leading online resource for entrepreneurs, business owners and professionals seeking business networking events, mixers and training seminars.
At the core of NetworkingPhoenix.com is a robust, comprehensive, and free-to-use online calendar with a complete listing of business and professional networking events, mixers, and seminars going on in the Phoenix Metropolitan area (about 216 events listed monthly). While it is absolutely free (and vehemently encouraged) for the community to post events and related content, NetworkingPhoenix.com goes a step further by vetting all such content for proper accuracy, validity, and taxonomy. By doing so, NetworkingPhoenix.com provides a much richer, flexible, and filterable user experience which helps everybody to find what they're looking for with less effort and more confidence.
Since its inception in October 2008, NetworkingPhoenix.com has skyrocketed in popularity quickly becoming one of the most visited websites local to Arizona, and even making a global imprint as one of the top 1% most visited global websites (click here for details). 41,789 members have joined in the 10 years 4 months NetworkingPhoenix.com has been around and the website's growth still shows no signs of slowing.
Membership at the site is absolutely free, takes less than a minute to signup, and consists of creating a simple professional profile (similar to a LinkedIn). Once a member, full access is granted to all event and event related information, as well as a very wide array of tools including event reminders, custom event filters (show only the events you're interested in), agenda management, event data exports to other popular calendars (Outlook, iCal, et al), and much more… seriously… and the list of benefits is ALWAYS growing.
NetworkingPhoenix.com also has a premium membership, the Networking Passport, which takes members beyond simply finding events to attend and actually provides FREE access into some of the most popular fee-based events, mixers and seminars in Phoenix. At only $9.97/month, the program is very inexpensive for the business professional looking to make contacts and build relationships at the right events (click here for more info).
Another very popular offering of NetworkingPhoenix.com is the quarterly Signature Events. These events attract approximately 1,500 business owners, entrepreneurs and professionals for an evening of mixing and mingling. To be notified of this event, and many more, please create a free profile on our site.
For Anyone looking for a quality corporate video find us at Blare Films Arizona.


Defines and revives curls, eliminating frizz. Hair retrieves softness, hydration, and shine, without being weighed down.
Made with a high concentration of colour pigments that blend perfectly with hair. Innovative technology that leaves hair ultra-soft without weighing it down.