Please join us for a book signing and lecture by Dr. Michael J. Bazyler, Professor of Law and The 1939 Society Law Scholar in Holocaust and Human Rights Studies at Chapman University. His new book, "Holocaust, Genocide and the Law: A Quest for Justice in a Post-Holocaust World," examines the history of genocide, the Holocaust, and the prosecution of the Nazis and their collaborators through the prism of the law.
Tickets are required; click here to reserve. MCLE credit for lawyers is available.
We are now seeking applications for our annual docent training program. We depend on our dedicated volunteer docents to lead tours for the thousands of students and other visitors who visit the Museum every month. During the training, which begins on Wednesday, September 27 and meets every Wednesday for ten weeks, you will learn about the history of the Holocaust, become familiar with the Museum's collection and exhibits, participate in tours and special lectures, and master gallery teaching techniques. Click here for more information.
This week o ur high school interns interviewed Holocaust Survivors Mary Bauer, Eva Wartnik and Gregory McKay, none of whom had previously given recorded testimony. The video recordings will be archived at the Museum so future students and Museum visitors can learn about the Survivors' experiences during the Holocaust.
Fred Heim was born in Berlin, Germany in 1926. Under Nazi German rule, he and his family lost their civil rights. It was not until 1938 when he witnessed Kristallnacht that he truly realized the severity of the anti-Jewish laws. He was able to obtain a visa and leave Germany for the United States just before the outbreak of World War II.
This is Fred's first time speaking at the Museum.
Betty Hyatt was born in 1934 in Antwerp, Belgium to Dutch parents. In May 1940, Nazi Germany invaded Belgium. Betty's parents fled with their family and intended to go to Surinam, then a Dutch colony, by way of Portugal. As they trekked out of Belgium, Betty's family was caught in Vichy France. Since they were not French citizens, they were not allowed to travel any further. They settled in a small town and soon received aid from the French resistance. Betty lived in France for the rest of the war under a false identity. After liberation, she learned that her father had perished in Auschwitz. Betty, her mother and brother immigrated to the United States in 1946. She settled in Los Angeles where she married, had two sons, and established a career as a social worker.
Joseph Alexander was born in 1922 in Kowal, Poland. He and his family enjoyed a comfortable and stable life until Nazi Germany invaded Poland in 1939. At the beginning of the war, Joseph's family fled and joined other relatives in the town of Blonie. In late 1940, Blonie's Jews were transported to the Warsaw Ghetto. Joseph's father bribed some guards to let Joseph and two of his siblings escape back to Kowal. This was the last time he saw the rest of his family. From Kowal, Joseph was sent to different concentration camps including Auschwitz-Birkenau. After the Warsaw Ghetto Uprising, he was sent from Auschwitz back to the Warsaw Ghetto to clean up the destruction's aftermath. As the Polish Home Army advanced toward Warsaw, Joseph was sent to camps in Germany, including Dachau, and then on a death march. He was liberated by American troops in 1945. He immigrated to the United States in 1949 where he married and had three children.


Employers are required to provide reasonable accommodations to employees with disabilities. Unfortunately, this does not always happen and, in some cases, employers barely make an effort to provide these accommodations or, worse, choose to discharge employees who have requested reasonable accommodations for a qualifying disability. If you have a disability that requires certain accommodations to perform the essential functions of your job, remember that the law is on your side. At Wrady & Michel, LLC, our Birmingham team of employment discrimination attorneys have a track record of success in advocating for victims of disability discrimination. If you have a disability, and believe you were discriminated against because of it, we will fight on your behalf to ensure you receive the justice and compensation you deserve.
Call our law firm today at (205) 265-1880 to get started on your case!
To accommodate an employee's disability, an employer must sit down with him or her one-on-one to identify what is needed to assist the employee in performing all essential functions of the job. If your employer neglects to perform this crucial step, it may have violated the law.
Under the ADA, disabled individuals are guaranteed equal opportunities in employment, transportation, public accommodations, state and local government services, and telecommunications. When it comes to the workplace, reasonable accommodations can come in many forms, such as modifications or adjustments to a job's requirements, the work environment, or another aspect of the job that will enable a qualified, disabled individual to perform the work. Some examples of accommodations that an employer can reasonably make include adjusting the starting time, making work facilities more accessible, modifying equipment, or providing audio amplification devices to those who have a hearing disability.
However, employers are not required to make accommodations that would be too expensive, or if the employee has a medical condition that could potentially pose a serious risk to someone else in the workplace or to himself or herself.
If you believe you were discriminated against due to your disability, or that your employer failed to reasonably accommodate your disability, you might be entitled to compensation for lost benefits, wages, and emotional pain and suffering. In some cases, employers might even be required to pay punitive damages. At Wrady & Michel, LLC, our Birmingham employment discrimination team of attorneys has over 15 years of combined experience representing employees. Our team has the experience and knowledge that is necessary to protect your rights as an employee. We will dedicate ourselves to helping you throughout this process, and work tirelessly to recover damages you may have suffered at the hands of your employer.
Learn more about how we can help you and call our office today at (205) 265-1880 to schedule a consultation with a knowledgeable member of our team.
At Wrady & Michel, LLC, our Birmingham employment law attorneys are dedicated to serving residents of Alabama who are victims of unfair workplace treatment. If you were discriminated against due to your disability, our legal team will stand by you and fight for your rights. Backed by over 15 years of experience, you can be confident in our ability to effectively represent you.


text:
Аннотация к книге "Suetonius"
High Quality Content by WIKIPEDIA articles! Gaius Suetonius Tranquillus, commonly known as Suetonius (ca. 69/75 – after 130), was a Roman historian belonging to the equestrian order in the early Imperial era. He is important to Christians because of his reference to the Historicity of Jesus. His most important surviving work is a set of biographies of twelve successive Roman rulers, from Julius Caesar to Domitian, entitled De Vita Caesarum. Other works by Suetonius concern the daily life of...
High Quality Content by WIKIPEDIA articles! Gaius Suetonius Tranquillus, commonly known as Suetonius (ca. 69/75 – after 130), was a Roman historian belonging to the equestrian order in the early Imperial era. He is important to Christians because of his reference to the Historicity of Jesus. His most important surviving work is a set of biographies of twelve successive Roman rulers, from Julius Caesar to Domitian, entitled De Vita Caesarum. Other works by Suetonius concern the daily life of Rome, politics, oratory, and the lives of famous writers, including poets, historians, and grammarians. A few of these books have partially survived, but many have been lost. He is mainly remembered as the author of De Vita Caesarum, best known in English as "The Twelve Caesars", his only extant work except for the brief lives and other fragments noted below.

redpajama_set_name: RedPajamaCommonCrawl


Sign up for our Summer Camp! The camp will run for 10 weeks, starting the week of June 3rd and ending the week of August 16th. Camps will not meet the week of July 1st. The camp is divided into subgroups based on age; each subgroup will meet once a week. Activities run 10 a.m. to noon and include a snack and a take-home craft.
Cost is $50.00 per child and must be paid in advance in order to hold a spot. It may be paid in person at the Judy Jasper Educational Center (open every day 10-4:30), or using the 'Donate' option on this website.
Register here using our Google Form.
If you have any additional questions, please email us at maryjowegnerarboretum@gmail.com or contact us on our social media platforms.


text:
using Poco::Util::Application;
using Poco::Util::Option;
using Poco::Util::OptionSet;
using Poco::Util::HelpFormatter;
using Poco::Util::AbstractConfiguration;
using Poco::Util::OptionCallback;

class TweetApp: public Application
	/// A very simple Twitter command-line client.
{
public:
	TweetApp():
		_status(Application::EXIT_OK)
	{
	}

protected:
	void defineOptions(OptionSet& options)
	{
		Application::defineOptions(options);

		options.addOption(
			Option("help", "h", "display help information on command line arguments")
				.required(false)
				.repeatable(false)
				.callback(OptionCallback<TweetApp>(this, &TweetApp::handleHelp)));

		options.addOption(
			Option("message", "m", "specify the status message to post")
				.required(true)
				.repeatable(false)
				.argument("message")
				.callback(OptionCallback<TweetApp>(this, &TweetApp::handleMessage)));

		options.addOption(
			Option("ckey", "c", "specify the Twitter consumer key")
				.required(true)
				.repeatable(false)
				.argument("consumer key")
				.callback(OptionCallback<TweetApp>(this, &TweetApp::handleConsumerKey)));

		options.addOption(
			Option("csecret", "s", "specify the Twitter consumer secret")
				.required(true)
				.repeatable(false)
				.argument("consumer secret")
				.callback(OptionCallback<TweetApp>(this, &TweetApp::handleConsumerSecret)));

		options.addOption(
			Option("token", "t", "specify the Twitter access token")
				.required(false)
				.repeatable(true)
				.argument("access token")
				.callback(OptionCallback<TweetApp>(this, &TweetApp::handleAccessToken)));

		options.addOption(
			Option("tsecret", "S", "specify the Twitter access token secret")
				.required(false)
				.repeatable(true)
				.argument("access token secret")
				.callback(OptionCallback<TweetApp>(this, &TweetApp::handleAccessTokenSecret)));
	}

	void handleHelp(const std::string& name, const std::string& value)
	{
		displayHelp();
		stopOptionsProcessing();
	}

	void handleConsumerKey(const std::string& name, const std::string& value)
	{
		_consumerKey = value;
	}

	void handleConsumerSecret(const std::string& name, const std::string& value)
	{
		_consumerSecret = value;
	}

	void handleAccessToken(const std::string& name, const std::string& value)
	{
		_accessToken = value;
	}

	void handleAccessTokenSecret(const std::string& name, const std::string& value)
	{
		_accessTokenSecret = value;
	}

	void handleMessage(const std::string& name, const std::string& value)
	{
		try
		{
			_twitter.login(_consumerKey, _consumerSecret, _accessToken, _accessTokenSecret);
			Poco::Int64 statusId = _twitter.update(value);
			std::cout << statusId << std::endl;
		}
		catch (Poco::Exception& exc)
		{
			std::cerr << exc.displayText() << std::endl;
			_status = Application::EXIT_SOFTWARE;
		}
	}

	void displayHelp()
	{
		HelpFormatter helpFormatter(options());
		helpFormatter.setCommand(commandName());
		helpFormatter.setUsage("OPTIONS");
		helpFormatter.setHeader("A simple Twitter command line client for posting status updates.");
		helpFormatter.format(std::cout);
	}

	int main(const std::vector<std::string>& args)
	{
		return _status;
	}

private:
	std::string _consumerKey;
	std::string _consumerSecret;
	std::string _accessToken;
	std::string _accessTokenSecret;
	Twitter _twitter;
	int _status;
};

POCO_APP_MAIN(TweetApp)

redpajama_set_name: RedPajamaGithub


Written through an skilled practitioner and coach, this step by step consultant breaks down the PRINCE2® method into bite-size chunks, giving transparent causes and useful illustrations in each one part. it is going to assist you successfully follow the rules, subject matters and procedures of PRINCE2® on your project.
The shuttle has been via unparalleled upheaval and alter. Plunkett's Airline, resort & go back and forth Almanac should be the entire advisor to this attention-grabbing undefined. After reeling from the consequences of the September eleven, 2001 tragedies, the shuttle company is now rising as a extra streamlined, effective and concentrated undefined.
Notes on Islamic Economics: Theories and InstitutionsIn this e-book I current the fundamental theories and the institutional arrange of Islamic economics. It contains chapters one via 11. Chapters one and try to solution the questions of 'what is Islamic Economics' and 'why we have to examine it', in addition they speak about problems with definition, scope, assets of information and relevance.
This textbook introduces the instruments and platforms of administration regulate at present utilized in companies. the point of interest is on how managers enforce and use administration regulate structures. The publication emphasizes the social, behavioural and situational dimensions of administration keep an eye on. It deals many useful examples and case reports, with recommendations or discussions.
Slated to be the go-to ebook for barbers and stylists looking good fortune within the hair this present day, Al Reid, higher referred to as "Alsmillions", covers every little thing from determining the distinct skills of barbers to tips on how to construct a effective shoppers from simply five consumers. As a grasp educator, CEO and entrepreneur, Al digs deep into the wealth of his over 26 years of expertise to proportion with you, the foremost components that offers a barber or stylist real good fortune during this aggressive box.


text:
Ella Swings Lightly è il quattordicesimo album della cantante Ella Fitzgerald, pubblicato dalla Verve Records nel 1958.

Tracce

Lato A
 Little White Lies (Walter Donaldson) – 2:31
 You Hit the Spot (Mack Gordon, Harry Revel) – 2:44
 What's Your Story, Morning Glory? (Jack Lawrence, Paul Francis Webster, Mary Lou Williams) – 2:38
 Just You, Just Me (Jesse Greer, Raymond Klages) – 2:19
 As Long as I Live (Harold Arlen, Ted Koehler) – 2:48
 Teardrops from My Eyes (Rudy Toombs) – 3:45
 Gotta Be This or That (Sunny Skylar) – 3:05
 Moonlight on the Ganges (Sherman Myers, Chester Wallace) – 2:22

Lato B
My Kinda Love (Louis Alter, Jo Trent) – 3:41
 Blues in the Night (Harold Arlen, Johnny Mercer) – 3:39
 If I Were a Bell (Frank Loesser) – 2:33
 You're an Old Smoothie (Nacio Herb Brown, Buddy DeSylva, Richard A. Whiting) – 2:45
 Little Jazz (Roy Eldridge, Buster Harding) – 3:02
 You Brought a New Kind of Love to Me (Sammy Fain, Irving Kahal, Peter Norman) – 2:18
 Knock Me a Kiss (Mike Jackson) – 4:06
 720 in the Books (Harold Adamson, Jan Savitt, Leo Watson) – 2:52

Bonus track riedizione 1992
Oh, What a Night for Love (Long Version) (Steve Allen, Neal Hefti) – 3:26
 Little Jazz (Alternative take) – 3:01
 Dreams Are Made for Children (Previously unreleased) (Mack David, Jerry Livingston, Max Meth) – 2:36
 Oh, What a Night for Love (45rpm 7" Single Version) – 2:24

Note

Collegamenti esterni

redpajama_set_name: RedPajamaWikipedia


text:
Susumu Watanabe (Tóquio, 10 de outubro de 1973) é um treinador e ex-futebolista profissional japonês que atuava como defensor.

Carreira
Susumu Watanabe começou a carreira no Consadole Sapporo.

Ligações externas
Perfil em Vegalta Sendai

Naturais de Tóquio
Futebolistas do Japão
Futebolistas do Consadole Sapporo
Futebolistas do Ventforet Kofu
Futebolistas do Vegalta Sendai
Treinadores de futebol do Japão


text:
Early Art: Finding Efficient Style
Gabe's Game
On an indie team, being efficient with your time is important. As a solo developer, it's imperative. Traditionally, when adventuring into the early artist process for video games, you'll have piles of concept art, mood sketches, character concepts, often even prop art concepts. You'll find an art team deliberating over details in a way an individual just can't. So how am I possibly going to make an attractive game solo? By being strategically artistic.
I'm going to build a character. My game is still in its infancy, so character art isn't the most important task on my list. However, this is my review process. By finding a design I like early on, I can see it in action and consider its weaknesses throughout development. Without an art department to critique my work, I need this sort of self-analysis along with community feedback. I want to work with a character that's lovable and memorable. Also, maybe a robot.
My first step is to clearly define what I need to communicate visually. I know that I want the player's feet to feel powerful to suggest that jumping off of things is how you deal damage. I also don't want to include text in my game, so I'd like to be able to emote a lot through the character. Generally, really expressive characters require a lot of animation, so I needed to figure out a way around that for this solo game. I came up with this little fella while imagining a character with a holographic iMessage-ish head:
So with this design, I can make the head a separate object. I can then animate facial expressions and communicate through imagery projected on the face, all while looping animations for the body. Quick and efficient expression, one goal met. However, the legs look weak and I want the art for this game to be a bit more involved than the above style, so I sketched a bigger version:
Closer to what I want, but the legs still aren't grabbing enough attention. I decided to take this design into 3DS Max. Having done 3D art far longer than game design or drawing, I feel more comfortable tweaking a block out quickly in 3D space.
I ended up squashing down the body and making it bulkier to better fit within collision boundaries I like. I've clearly amped up the legs, but because I've also intensified his shoulders and hands, they aren't carrying the weight I want them to. The above is a rectangular silhouette, if I want the base to feel like the heaviest point, perhaps a triangle would work better.
The triangular shapes wonderfully depict the composition I was aiming for! This design feels way more powerful and deliberate. I'm still able to emote efficiently, the feet are obviously the most powerful part of the body, and I can fit the character within my preferred collision boundaries. Ultimately, removing unnecessary detail and refocusing on the visual information I need to communicate was the solution.
I decide to head back to 3D. I'm thinking I want to do 3D flat lit characters rendered into sprites with 2D handpainted environments. My logic is really just that I have plenty of experience with both of those things. I would never recommend exclusively sticking to what you know, but learning to program is enough educational exploration for one game.
Ended up throwing in more detail than I had anticipated, but I'm pretty satisfied with how they're looking. I don't want to get too attached to any part of the character this soon, so I've kept them very modular. Preparing for inevitable changes to your art and style is imperative this early on. Gameplay takes priority over visuals, so I don't want to limit myself with something that's difficult to tamper with.
All in all I'm off to a good start! The world for my game is now brimming with color in my imagination. I can see an iconic personality for my character and ways to make design points clearer than they could be without him. Best of all, the time commitment to this early character draft was pretty small. Now with a clear vision for my experience, I can really start work on building a world. There is a lot of work to do, so I'd better get movin...
William's Comment: I've been waiting to see an art blog post from you this whole time because, while you're quite adept at game design and finding fun in prototyping, art is an area where I frequently find a loss for words when observing your process. Even with super-fast time-saving techniques and a full preparation to change up the design in the future, what you've created has classic design, a world of opportunities for emotion and dynamic action, and a robot look more fun than Keiji Inafune has been capable of since Megaman X.
The holographic speech-bubble head especially gives an outstanding contrast which is mirrored in the color design: a soft, cute, baby-blue head with rounded corners, curious bright eyes, and clearly delicate in its holographic artifacting emanates from a a red-and-grey metal, boxy, agile-yet-powerful mechanical hard body. Its body is powerful and hardened, but the personality is curious and delicate. All I've got in my game is a goofy looking skeleton.
If I had to give any advice moving forward, it would be to be wary of how you convey perspective in a truly 2D game. In fact, even in 3D platformers the following could be an issue: perspective shots can lead to imprecise platforming. While your character seems to be rendered orthographically, he seems (at least in some images) to be rendered with a non-orthographic world in mind. That is to say, that the character's feet won't be even on the ground.
Since your game's prototype shows an emphasis on precise jumping that controls evasion, attacking, navigation, and everything, allowing for absolute visual precision through an orthographic view would be optimal.
For the people reading who may not know what I'm talking about: Orthographic projection forces a perspective in which objects are displayed without perspective, usually as having very clear border edges and straight lines.
That's part of why games with lots of precision platforming like Super Meat Boy or New Super Mario Bros (both pictured below), or even Sonic The Hedgehog or Megaman keep an orthographic perspective for the most part.
When there's a bit of leeway to what can be considered a the collision line of a surface, scenarios with perspective look nice most of the time, but are better suited for games that rely less on platforming and maybe more on combat or collecting items. It's a style typically best for less movement-intensive games like Kirby or Commander Keen (both pictured below).
Anyway, I'm merely commenting off of what was likely a test render, but I still hope it's something you keep in mind as you continue your design (confirmed that you were already planning to go ortho after a short conversation in Skype, whoops). If it was something you were already considering, then I hope that at least the readers got to learn something interesting!
Got questions, opinions or cool early game art to show off? Put all of that into the comments!
Want more immediate posts from us? You can follow William on Twitter here and follow Gabe on Twitter here.
Posted by Gabriel Priske


CUP's work is largely supported by the generous donations of individuals and foundations that care about the city and how it works. Every donation, from $5 to $50,000 helps us to keep producing the high-quality projects you have come to expect from CUP.
To make a secure online donation, please use the form below and then proceed to a check-out through Paypal or Network for Good.
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Many organizations match their employees' charitable contributions, doubling (and sometimes tripling) the impact of your gift.
Ask your employer if they offer a matching program. It only takes a few minutes!
If you have questions, contact us at donate@welcometoCUP.org.
Companies who have provided matches in the past include Boeing, Deutschebank, Expedia, the Ford Foundation, Google, and Penguin Random House, among others.
Checks should be made out to: the Center for Urban Pedagogy.
CUP is a 501(c)(3) not-for-profit organization. All cash and in-kind contributions to CUP are tax-deductible and fully support our educational programming.
CUP is extremely grateful to the following donors who supported our work in 2018.


The healing of the historical memory is an important condition for reconciliation in the Ukrainian society. For curing the past, it is important to rethink little-known history; one has to know and understand oneself and the Other. Dialogue is an effective form to achieve it. The 'Dialogues in the Museum' project involves the introduction of different methods of work on dialogues into the museum's activities, in particular in the context of history and memories. It will provide the participants in our events with an opportunity to rethink the totalitarian past and change their historical consciousness.
The project involves using the methods suggested by the partner organizations, the 'Foundations of Liberty' Youth NGO and OWEN – the Academy of Gender Equality.


The Fall is the most wonderful time of the year. Why? Football season. All three of my young boys play football; between them, that's three games and a dozen practices every week.
This may be unsettling to some, but the earliest followers of Jesus did not refer to themselves as Christians. I am rather glad about this because the word "Christian" has too much baggage attached to it.
A few weeks ago I read that doomsday shelters are making a big comeback. Now, I've never been in one of these safe havens, but I am told they were all the rage fifty years ago.
My southern grandmother had a saying she used most every day: "Get your goat." It was one of those wonderful phrases that could be employed in any number of relevant situations.


text:
Shinfield mum shocked after finding "fly" in son's birthday cake
Jag Shah bought the dessert from Cake Box in Oxford Road but owners say it was ash from a birthday candle
The cake bought by Jag Shah
A Shinfield mum who found what she believes was a fly in her son's birthday cake has filed a complaint to Reading Borough Council.
Jag Shah bought the dessert from the Cake Box in Oxford Road, West Reading on Saturday, November 14 but claims she discovered a fly intermingled in the cream on top of it.
However, the manager of the shop denied there was a problem with the cake and suggested it could be ash from a candle.
Mrs Shah had bought the cake for her son Sohum's 19th birthday but returned it after making the discovery. However, when staff denied it was a fly she called the council to ask their environmental health team to take a look.
Mrs Shah said: "The worst thing about it is they (the shop) are in denial about it.
"They didn't even apologise or say it was a mistake.
"It was embarrassing because I had my family round and it was my son's birthday.
"The fly was intermingled in the cream so can't have happened after we opened it.
"We felt quite ill afterwards."
Mrs Shah was offered a full refund for the cake, which cost £17.99, but she instead turned this down and wanted £500 as compensation.
"That refund means nothing to us," she added.
"It's not what we are looking for after all the trauma we have been through."
She has since complained to the council's environmental health department about it.
Spokesman for the council David Millward confirmed a complaint had been received and an officer would be investigating the premises shortly.
Mrs Shah added: "You expect top hygiene from them and I have bought cakes from them before but won't be going back there now."
Cake Box manager Ram Singh said: "There is no way a fly could have got into the cake.
"It was some ash from a candle, not a fly.
"Over the last three years we've not had any complaints.
"We've never had any complaint of this sort."
Reading Borough Council
Shinfield
Slough couple adopt 30 disabled dogs nobody wants


text:
Q: How to rerun failed features in karate? Can anyone help me to rerun failed features in karate. below are the cucumber options and runner test which is using for parallel -
@CucumberOptions(features = "classpath:features/xxxxx/crud_api",
        format = {"pretty", "html:target/cucumber","json:target/cucumber/report.json", "rerun:target/rerun/rerun.txt" })

@Test
    public void  test() throws IOException {
        Results results = KarateRunnerTest.parallel(getClass(), threadCount, karateOutputPath);
        assertTrue("there are scenario failures", results.getFailCount() == 0);
    }

A: Here is my reusable implementation using karate-1.0#retry-framework-experimental,
Results retryFailedTests(Results results) {
        System.out.println("======== Retrying failed tests ========");

        Results initialResults = results;
        List<ScenarioResult> retryResult = results.getScenarioResults().filter(ScenarioResult::isFailed)
                .parallel()
                .map(scenarioResult -> initialResults.getSuite().retryScenario(scenarioResult.getScenario()))
                .collect(Collectors.toList());
        for (ScenarioResult scenarioResult : retryResult) {
            results = results.getSuite().updateResults(scenarioResult);
        }
        return results;
    }

This java function takes care of retrying failed scenarios in parallel. You can check karate-timeline.html report to verify if the failed scenarios are retried in parallel.

A: Sharing my solution for when using the standalone JAR, implemented as a RuntimeHook (requires Karate 1.0+):
package retries;

import com.intuit.karate.core.Tag;
import com.intuit.karate.RuntimeHook;
import com.intuit.karate.core.ScenarioRuntime;
import com.intuit.karate.core.ScenarioResult;
import com.intuit.karate.core.FeatureRuntime;
import com.intuit.karate.core.Scenario;
import com.intuit.karate.core.StepResult;
import com.intuit.karate.core.Step;
import java.util.HashSet;
import java.util.List;

/**
 * RuntimeHook that implements @retries tag.
 *
 * Usage:
 *   - compile this into a jar with:
 *       javac --release 8 -cp path/to/karate.jar *.java
 *       jar cvf retries-hook.jar *.class
 *   - tag your tests like @retries=3 to retry e.g. 3 times (4 total attempts)
 *   - invoke karate tests with:
 *       java -cp path/to/karate.jar:retries-hook.jar:path/to/java" com.intuit.karate.Main path/to/tests/dir --hook retries.RetriesHook
 */
public class RetriesHook implements RuntimeHook {

    private static final HashSet<Scenario> RETRIES_ATTEMPTED = new HashSet<Scenario>();
    private static final HashSet<ScenarioResult> RETRIES_SUCCEEDED = new HashSet<ScenarioResult>();

    @Override
    public void afterScenario(ScenarioRuntime sr) {
        if (!sr.isFailed()) {
            return;
        }

        int configuredRetries = 0;
        for (Tag tag : sr.tags) {
            if ("retries".equals(tag.getName())) {
                configuredRetries = Integer.parseInt(tag.getValues().get(0));
                break;
            }
        }
        if (configuredRetries <= 0) {
            return;
        }

        for (Scenario s : RETRIES_ATTEMPTED) {
            if (s.isEqualTo(sr.scenario)) {
                // we've already kicked off retries for this Scenario
                return;
            }
        }
        String scenarioName = sr.scenario.toString();

        RETRIES_ATTEMPTED.add(sr.scenario);
        int retryAttempt = 1;
        while (retryAttempt <= configuredRetries) {
            System.out.println("Scenario " + scenarioName + " failed, attempting retry #" + retryAttempt);
            ScenarioResult retrySr = sr.featureRuntime.suite.retryScenario(sr.scenario);
            if (!retrySr.isFailed()) {
                System.out.println("Scenario " + scenarioName + " passed after " + retryAttempt + " retries");
                // Mark the original ScenarioResult as passed on retry, so it can get filtered out later in afterFeature.
                RETRIES_SUCCEEDED.add(sr.result);
                sr.featureRuntime.result.getScenarioResults().add(retrySr);
                return;
            }
            retryAttempt++;
        }
        System.out.println("Scenario " + scenarioName + " failed all " + configuredRetries + " retries");
    }

    @Override
    public void afterFeature(FeatureRuntime fr) {
        // afterScenario is called before the original ScenarioResult is saved,
        // so we can't use Suite.updateResults() :/
        // Instead, we add the passed ScenarioResult above and then filter out the
        // failed one here.
        if (fr.result.isFailed()) {
            List<ScenarioResult> scenarioResults = fr.result.getScenarioResults();
            scenarioResults.removeIf(sr -> RETRIES_SUCCEEDED.contains(sr));
            fr.result.sortScenarioResults();
        }
    }
}

A: This is not something that Karate supports, but in dev mode (using the IDE for example) you can always re-run the failed tests manually.
You seem to be using annotation options not supported by Karate, e.g. format. Read the docs for what is supported it is limited to features and tags.
EDIT - Karate 1.0 has experimental support for this: https://github.com/intuit/karate/wiki/1.0-upgrade-guide#retry-framework-experimental

redpajama_set_name: RedPajamaStackExchange


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Southern Staffordshire Community Energy
…..building energy resilence
We're a BenCom
Our Community PV Projects
Our Community Funds
← Best Energy Efficient Community Project Award, Nov 2013
Posted on August 17, 2017 by Pam B
Share offer closes 2 days early, raising over £335,000!
We are delighted to report that on 23rd September 2016 our second community share offer reached its target raise of more than £335,000, in the end closing two days early due to oversubscription. All the PV systems which were planned to be purchased with the money have been installed, commissioned and registered for the Feed-in Tariff (FiT) and all this achieved before the FiT rate dropped on 30 September.
The PV systems have been installed on seven properties belonging to the University Hospitals of North Midlands NHS Trust (including Stafford and Royal Stoke hospitals), and on St Giles Hospice, Whittington, the latter being in addition to those already owned by SSCE there. The primary reason for the installations, after saving CO2 emissions, is to enable the establishment of a scheme, with the surplus, to help those in the area affected by health conditions related to fuel poverty. Consultants in A&E will identify those people who continually present there with such health conditions and will request the patients' permission to refer them to fuel poverty charity, Beat The Cold, who will then help the patient address as many factors as possible that are contributing to their inability to maintain a warm, dry home. While the first year's FiTs are building up, we are delighted to say that this community work will be launched with the £10,000 proceeds resulting from the scheme's winning first prize in NEA's Energy Impact Awards 2016.
We are overjoyed at getting to where we are, and are catching our breath for a while, but nevertheless we will post updates on the progress of the community work here when we have them, so do come back and see how we are getting on.
Tweets by @sscenergy


A) Take the time to input all the information.
B) Have all the information available in the first place.
So, is organizing software a worthwhile investment or a waste of time? Well, it depends a lot on the individual's needs and the individual programs on offer. One feature that may make a particular program worth its salt is the ability to replace several programs at once by making many diverse features available through the one program.
For example, decent organizing software should be able to provide all of the following: act as a dictionary, convert metric, traditional, and imperial units, perform advanced calculations, view and clear your computer's history, encrypt files, allow for file editing, provide a venue for sketching and drawing, view photos, create websites, organize and play videos, view and edit databases of varied formats, create databases, provide computer security and system information.
However, many people never get beyond the basic secretarial skills of such software, which acts much like a calendar that gives you reminders, and stores information like an automated rolodex. In its usual capacity, organizing software helps you manage your time in terms of appointments, meetings, projects, events, and workflow and allows you to plan even years in advance for important dates in your personal and professional life.
Organizing software can help you prioritize your harried work life by helping you set deadlines and by tracking the progress and completion of tasks. In theory, this should help relieve some of your work-related tension, but whether or not this is effective in practice is anyone's guess. Some people swear by these programs, but such people tend to be the type who like a lot of gadgets and such and use them to bolster their feelings of preparedness and self-confidence. It's not clear that this type of software is any more than a psychological prop for very busy business people. Be that as it may, if the price is right and it feels good, organizing software may end up making your life a little easier.


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LeaguesEnglish ChampionshipLATEST ARTICLESEnglish Premier LeagueLeeds United
4-2-3-1 Leeds United Predicted Lineup Vs Millwall: Adam Forshaw To Start For The Peacocks?
By Abhinab Ghosh
Abhinab Ghosh
A 26-year-old sports writer and an aspiring football coach who has road-tripped across the Scottish Highlands, but has never been to Wales. Sucker for cliff-hangers and catchy riffs. Known to be a grunger and not to be a stranger.
Leeds United will play hosts to Millwall at Elland Road on Saturday after suffering three defeats in their last four outings in all competitions. Leeds manager Thomas Christiansen will be desperate to bounce back against Championship strugglers Millwall with three crucial points up for grabs. The Peacocks are well in contention to secure a playoff spot at the end of the season. They are currently in 7th place with just goal difference separating them from a playoff place which is being occupied by Sheffield United right now. A big victory at home versus Millwall should be enough for them to get into the top 6 at the end of this game week.
The Lions, on the other hand, are in dire need of some results to go their way but are temporarily out of relegation danger. Neil Harris's side are sitting in 16th place in the English Championship standings, six points above the relegation zone going into this clash versus Leeds United. The recent history of the fixture does not favour anyone as both sides have tasted four victories each in their last 8 encounters in the league.
Thomas Christiansen is expected to opt for a 4-2-3-1 formation and their new signing from Middlesbrough, Adam Forshaw is set for a medical ahead of this game. He is highly anticipated to play some part in this match and might be in line for a start with midfielder Eunan O'Kane suspended for this clash due to a red card in their last league match.
4-2-3-1 Leeds United Predicted Lineup To Face Millwall
Felix Wiedwald will once again start in goal for the Peacocks and is expected to be protected by a back four of Pontus Jannson and Liam Cooper in central defence while Gaetano Berardi takes his place at right-back and Vernon Anita starts on the left-hand side of the backline.
Thomas Christiansen will be hoping that his defenders can keep a clean sheet versus Millwall which will give them a good platform to boost their goal difference.
Kalvin Phillips and new signing Adam Forshaw will line up as the holding midfielders and the trio of Pawel Cibicki, Pablo Hernandez and Ergjan Alioski will play just ahead of them. They will be responsible for creating and scoring goals for the Peacocks and put an end to their recent poor run of only once in their last four games in all competitions.
Kemar Roofe is expected to lead the lines for Leeds United up top. The 25-year-old will look to add to his goal tally of 10 goals in 27 matches in all competitions when he laces up to face Millwall on Saturday.
milwall
predicted lineup
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Is world domination the new mantra for Irish-based start-ups?
Trezeo co-founder and CTO Flavien Charlon. Image: Luke Maxwell
Investors at NDRC's Investor Day were inspired by diverse ideas that can scale globally.
Real products that meet real market needs and that can scale globally were the hallmark of the latest tranche of NDRC start-ups.
That was the view of the various investors on Investor Day when Trezeo – creators of a platform that can provide income stability for the legions of gig economy workers out there – was selected as the overall winner. The audience vote went to Izzy Wheels, headed by sisters Izzy and Ailbhe Keane from Galway.
'The potential for world domination is there'
– DAVID BOWLES
Headed by CEO Garrett Cassidy and CTO Flavien Charlon, Trezeo's platform ensures reliable and regular payments for workers. It is launching a pilot in the UK in November and is raising funding to launch globally in 2019. The technology recently won the Payments Dragons' Den competition at PayExpo Europe in London.
Income smoothing for the gig economy
Charlon said that the company is trying to address the issue of income volatility for self-employed people in the gig economy.
"The UK is going to be our first step. The UK is one of the biggest countries in terms of the number of self-employed people in Europe and, from our research, 44pc of those people cite income volatility as one of their top three business problems and we are addressing that."
So, how does it work? "Essentially, it is a business account and what they do is, they redirect income to that account and we smooth the income that they receive every week so that they receive a fixed amount based on their average income.
"It is based on savings and lending so that we can give them top-up when they need lending, but this is interest-free, unlike overdrafts, which can be very expensive. Our product is interest-free and based on a subscription fee.
"Technically we are not a bank, but we are working with regulated partners. Essentially, we are a cashflow management tool that is selling peace of mind for customers in the gig economy who don't have to worry as much about income going up and down."
"The potential for world domination is there," said David Bowles from Delta Partners.
"Our view was that this is a company that could really scale. For people in the gig economy, being able to manage a varying salary every month is a need that is only going to increase. Trezeo will solve that. They are smart guys and they are experienced and have the right connections. There are no barriers to their growth. World domination is definitely within its reach."
The other judges were unanimous.
"For us, Trezeo was quite a clear winner in terms of the opportunity to build a global scale technology business," explained Draper Esprit's Nicola McClafferty.
McClafferty said that all 11 start-ups that presented earlier this week showed originality and focus. "Often [as investors], we find ourselves looking at really interesting products that are searching for a market. The companies were also coming at it from a commercial standpoint and solving a very real need."
Seasoned tech entrepreneur and investor Steve Collins, who co-founded Havok and who has an interesting dual existence as chief scientist at Swrve and as a venture partner at Frontline Ventures, echoed McClafferty's point.
"Primarily, it was the diversity of the different teams. There was a huge variety of different teams and different approaches. Secondly, we saw great domain expertise on the teams. These were teams that had problems identified and produced real working solutions."
But when it came to Trezeo, the global opportunity was key. "It's a huge market," said Collins. "The world is changing and the nature of work is changing. The gig economy is changing how people work, how they get paid and manage their finances."
In terms of the start-up landscape, Collins said that perceptions of founders and entrepreneurs as a valid career choice have changed. "This has permeated all the way through the education system. In particular, the university sector is doing very well in promoting the entrepreneurial career. Every university in Ireland now has some programme to help people on their journey.
"What has not changed is the overall problem in looking for customers, identifying customer needs and identifying solutions to existing problems rather than starting from being an idea or technology looking for a problem to solve."
Product diversity
For NDRC CEO Ben Hurley, the diversity of the companies that pitched on Investor Day speaks to the interesting blend of domain experience of the various founders.
"They already had customer engagement and validation of problems.
"They had a ready solution and technology and they were coming at the problem with deep insight and understanding."
When it came to Trezeo winning, Hurley said that the company is tapping into a global problem with an elegant and robust solution.
"This is a solution that when you provide it, [it] will start to grow to significant scale with the potential for thousands of users."
David Tighe, head of enterprise and innovation at Bank of Ireland, sponsors of the Investor Day at NDRC, remarked on the global ambition behind Trezeo and other start-ups to emerge from Ireland.
"When you look at companies like Plynk and others that have emerged in the last decade, they are saying, 'We are Irish, but we are taking on the world and we stand out.'"
Related: entrepreneurs, Accelerators, NDRC, funding and investment
Waterford start-up Klearcom wins €25,000 at ArcLabs Investor Showcase
Dogpatch Labs and regional hubs win €17m NDRC contract
NDRC to be wound down after losing tender for State-backed accelerator
EU makes equity investments in 42 innovative start-ups


Missed The Grammys last night? It's ok. It was pretty lame, we made some funny comments about it on our Twitter @theaudioperv and we have videos of all the performances. Enjoy the videos.
Dave Matthews Band performed "You & Me" and "Shake Me Like A Monkey" on Saturday Night Live on 11/21. Check it out inside.
Dave Matthews Band performed "Why I Am" on the Tonight Show with Conan O Brien on 9/14. Check it out inside.
Dave Matthews Band were on the Late Show with David Letterman on 7/31. They played the fastest version of "Funny The Way It Is" that I've ever seen. Check it out inside.
Dave Matthews Band stopped by the Late Show with David Letterman on 7/27 and performed "Why I Am." Check it out inside.


What if you were not you but some other creature? A cat? A dog? A sea turtle? By imagining yourself as something else you learn what all creatures share and how we are all connected by patterns of being. Combining a meditative poem with playful color-it-yourself images, If ends with a empowering message to be happy and at peace with yourself.
In the Summer of 1991, Daniel won a three month study grant to anywhere in the world. His fascination with British writers hearkening from the Lake District like Beatrix Potter, William Wordsworth, John Keats and many others, led him to the fells of North West England. Here, between the River Lune and River Eden, in the small remote village of Ravenstonedale, Daniel set up a studio and began teaching art at the local one-room school house. After gaining the trust of the faculty and students, he embarked on documenting the daily routine of the young students with a special focus on the recess period. Children of Cumbria is the resulting 150-page book of insightful black and white photographs culled from thousands of images. It reveals the interpersonal dynamics, character and habits of children not yet encumbered by technology and city-life. A "portrait of playtime" is combined with intimate moments of solitude expressing a deep connection between children and nature.
A retro trilogy with a precocious cast of three. The Back Talk Trio has a lot to say. Meet THE SMART ALECK – but you probably already know one. Have a CHAT WITH FAYE – careful though, she can be snippy. And whatever you do, do not answer THE MONSTER AT THE DOOR – he'll eat anything and everything and just want more. Trust us, these three short chapters will be just enough!
Hello new baby! The world is full of wonder. You cannot speak yet, but the sounds you make will soon be words. Yay! Eeek! Hi! Oh! You! Oooh Baby starts with YOU! The long vowel sound "U" can say so much like CHEW! Or BOOO! Or POOO! You will find them all and so much more in this fun little book. WEEHOO!
Two twin boys discover the joys of summer at the edge of the vast blue sea. The ocean churns and chortles, spraying the boys with morning mist. Splish! Splash! A veil of sea froth reveals magical starfish! The boys fill their pails with these strange beautiful creatures. And just before the mysterious deep reclaims its bounty, the clever twins share a secret message just for you and the universe. Now Mama and Papa call the boys home to their cozy cottage by the sea. Dusk settles and the moon glows. With not a single word, this simple book says so much!
Mr. Grand is grand indeed! A rotund fellow full of hot air! When he trips on a ball at the start of his stairs, he soon finds himself sailing through the air like a balloon! He might just as well enjoy the sights and what a view he has from so high above! Rolling hills, and oceans blue. Farms and towns and cities too with tiny people waving far below. Oh no! They think he is a UFO! Mr. Grand will never be the same! A cautionary tale with a twist, this silly book ends with a wink!
It's spring! A sweet little girl rushes from her home. Everywhere she can see, daisies are in bloom! A breeze rustles her hair and soft grass tickles her toes as she skips through the daisy field with bare feet. Now she stops to pick flowers and a little ladybug flies closer to see what she is making. A daisy crown of course because she is the princess of the world! But now the sun is setting and she must hurry home. This book shows you that sometimes the best things in life are fleeting, like a dreamy spring day filled with flowers.
One sunny winter day, a child has a wonderful time building a snowman. But what happens to the snowman after the child goes home? A wordless story full of fresh, cold air and the beauty of winter follows the play of light and the natural rhythm of the unfolding day. A new way of looking at the world waits inside the covers of this delightful little book.
A bedtime meditation for young children, this little book is designed to open minds by closing eyes. It introduces complex ideas like chakras, life force, spiritual travel, and interconnectivity in a simple and effortless way. The Dalai Lama says "If every 8 year old in the world is taught meditation, we will eliminate violence from the world within one generation." This magical book is the perfect beginners guide to peace and well-being. With Close Your Eyes you can hold the whole world in your hands. And if it doesn't save the world, at least it will help put your kid to sleep!
"Better watch the other side of the hill!
So says locally famous outside artist Clyde Jones from Carboro, NC.
Clyde makes critters from Haw River wash up.
He paints his house with swirls of amoebas and naps on the porch with a pack of feral dogs. This book documents Clyde and his peculiar world through haunting black and white photography and laconic poetry. A strange portrait of the American South emerges from these backwoods where Clyde's Dogs roam freely and lone men seek solace in scraps of driftwood.


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Tag: WWE
Win Tickets to WWE March 2nd at Silence the Violence!
On Saturday night March 2nd NCW continues its 2013 Season when we return to the Elks Lodge [60 Clyde Street] in West Warwick, Rhode Island for Silence the Violence XII. In conjunction with Matt's WWE Collectibles and in the spirit of "WrestleMania Season", Northeast Championship Wrestling is raffling off a pair [2] of tickets to WWE's Road to WrestleMania live at the Dunkin Donuts Center on March 16th.
While raffle tickets will be available in West Warwick for purchase, you can enter to win these tickets to WWE just by purchasing an NCW ticket for Silence the Violence, where you will automatically be entered into the drawing!
For more information, please be sure to like us on Facebook at www.facebook.com/NCWwrestling!
PRESS RELEASE: NCW Returns to West Warwick, RI Saturday March 2nd
WEST WARWICK- On Saturday night March 2nd Northeast Championship Wrestling's 2013 wrestling season continues when we return to the Elks Lodge in West Warwick, RI [60 Clyde Street] for our annual winter clash Silence the Violence. Competing in a seasonal format from February through November, for sixteen years NCW has presented a unique night of entertainment for fans bringing forth our larger than life characters, dynamic storylines, and incredible athleticism all while providing a unique experience for fans of all ages.
When NCW returns to West Warwick for the first time this Season, we'll see the Monarchy ["Royalty" William King & Zachary Pierre Beaulieu] step up to challenge the NCW Tag Team Champions at Silence the Violence, presenting a unique challenge for the champions. King, a former New England Champion who embraced his royal roots after being one of NCW's most popular competitors, has found a regal ally in Zachary Beaulieu, who truly believes he is above the lower class of West Warwick and New England. The challengers, confident in their capabilities in winning gold will square off against whoever wins the Tag Team Championship Match a week earlier in Norwood, MA at COLLISION COURSE. Whoever the champions are, the Monarchy has promised a victory on March 2nd regardless.
West Warwick will also see the egotistical "Dynamite" Doug Summers return to the Elks Lodge, proud of his deceit and duplicity at the expense of his former tag team partner and best friend Steve "The Turtle" Weiner last November. Weiner, reluctant to show his face in NCW since his attack, has allowed NCW Commissioner Dean "The Beast" Livsley to enlist the help of Warren's own Rob "The Giant" Araujo to teach Summers a lesson in respect, going one on one with the arrogant former Heavyweight Champion at Silence the Violence.
The NCW New England Champion Kevin Perry will also be in action on March 2nd, when he defends his New England title against three other contenders in a Four Corners Match, Perry's toughest challenge to date.
ALSO appearing in West Warwick will be the brotherly duo of David & Eddie Loomis, the Lumberjake, "RIOT" Kellan Thomas, NCW 2012 Wrestler of the Year "Simply the Best" GA West, "The Original Showoff" Mike Paiva, NCW 2012 Rookie of the Year Anthony Greene, Pacifico, Big Bully Rezner and many more!
A special raffle will also be taking place at Silence the Violence as Northeast Championship Wrestling will be giving away a pair of tickets to WWE's Road to WrestleMania, which comes to the Dunkin Donuts Center on Saturday night March 16th. How do you enter the raffle? Just by SHOWING UP to NCW Silence the Violence. One NCW ticket purchased automatically enters you into the raffle for WWE, with additional raffle tickets available to purchase.
The West Warwick Elks Lodge is located at 60 Clyde Street in West Warwick, RI. Doors open at 7pm with a special 7:40pm start time for the wrestling action to begin. Tickets are only $10 at the door for adults and only $5 for all kids twelve and under. For up to date information on Northeast Championship Wrestling be sure to visit us online at http://thencw.com and like us on Facebook at http://www.facebook.com/NCWwrestling.


When you exhibit in an island space, you are making a major marketing commitment. The costs are larger, the expectations are higher and the risks are greater. But so is the potential.
So you can be better prepared for the unique challenges faced by island exhibitors like you Skyline have created the Trade Show Tips for Island Exhibitors Book. It contains 26 articles previously published in the Skyline Trade Show Tips blog and three worksheets from Marc Goldberg of Marketech.


Easter doesn't always have to be for the kids. This year, I made an Easter basket to surprise one of my mommy friends. It's full of some yummy candy and things to help her relax. Us moms can get pretty stressed out after all! Along with the candy, I included a couple nail polishes, an adult coloring book, and some colored pencils. This is definitely an Easter basket that I would like to receive!
I went to Target to get some Easter candy to fill the basket. I picked up some Easter M&M's White Strawberry Shortcake, Easter DOVE Peanut Butter Eggs, a DOVE Milk Chocolate Bunny, Starburst Sweet & Sour Jellybeans, and a Starburst Carrot. Target Super Stores will be hosting a sampling event on March 20th. This would be a perfect time for you to pick out candy for your Easter baskets! Click here to save on MARS Easter candy and click here for some Wrigley Easter candy coupons.
I love the cute Starburst Carrot, and the pretty Easter M&M's White Strawberry Shortcake. These M&M's are only being sold for a limited time exclusively at Target. If you are a fan of white chocolate, you should definitely give them a try. These are perfect candy choices for a mom!
I made these printable Easter tags to attach to the basket. They say "Somebunny is thinking of you!" So cute! You could use these tags for friends, neighbors, or even teachers. Download the free printable here.
Print the tags on some cardstock, cut them out, and punch a hole in the top.
Glue a tiny pom pom on the tail to make them extra cute.
I put the basket in a cellophane bag and tied a tag on it with some baker's twine. I think I'm just going to drop it off at my friend's doorstep anonymously and run. Surprises like those are always the best!
The perfect Easter basket for a stressed out mom!
What do you think? What would you love to have in your Easter basket? For more great Easter basket ideas go here.


The Foundations of Interprofessional Education and Practice Course will be offered during the 2018-19 academic year to students enrolled in the Bachelor of Science in Nursing, master's entry-to-practice Clinical Nurse Leader, Doctor of Pharmacy, Doctor of Dental Surgery, Dental Hygiene, Medical Doctor, and Doctor of Physical Therapy programs. Faculty from the schools of Dentistry, Medicine, Nursing, and Pharmacy will work with interprofessional student groups who will be completing introductory interprofessional education content through six modules (three face to face and three online, delivered via Blackboard) during the fall and spring semesters.
Full-time UMB faculty member with interest in facilitating interprofessional education.
Faculty will need to be able to commit to 20-30 hours across the two semesters. Each school will decide whether the faculty selected for this course will receive $2,500 as a salary stipend or for professional development. Each school reserves the right to use the funding to benefit the school if this teaching assignment is within the faculty member's workload.
Complete the Foundations of IPE Course Application form and submit it no later than noon on Friday, Sept. 14, 2018. Application forms should be submitted to Patricia Danielewicz pdanielewicz@umaryland.edu as an email attachment. Applicants will be notified of their selection by Sept. 28, 2018.


shape, (we used shells) and any veggies you like, (we like carrots) in chicken broth. Add butter, parmesan, black pepper, and scallions. It doesn't get any simpler than that. Delicious, wholesome, and we swear it'll cure a winter cold. Ok, maybe not, but it is comfort food at it's best.
Heat the chicken broth and water in a large shallow saucepan over medium high heat until it just starts to boil.
Reduce heat to low, add pasta and veggies, and simmer gently for about 10 minutes, checking the pasta for doneness.
As soon as the pasta is cooked to your liking, remove pan from the heat and stir in the butter and then the parmesan.
Add the scallions and stir.
Use a slotted spoon to put some pasta in each bowl, then ladle over as much broth as you like.
Top with lots of fresh grated parmesan, some pepper, and a few more scallions if you like.
If you want to make this a more substantial dinner, add about a cup of shredded cooked chicken once the pasta is cooked!


text:
Huriti ili Hurijci (hur. Ḫu-ur-ri) su bili narod Starog Istoka tijekom brončanog doba. Njihovo podrijetlo nije poznato niti se huritski jezik svrstava u iti jednu pod poznatih jezičnih porodica. U povijesti se prvi put pojavljuju krajem 3. tisućljeća pr. Kr., a sljedećih tisuću godina njihovim naseljenim područjima uglavnom vladaju Hetiti. Najveći uspon Hurita bilježi se oko 1500. pr. Kr. kada nastaje kraljevsko Mitanija, većinski huritske države s indoarijskom vladajućom elitom. Oko 1000. pr. Kr. huritsko stanovništvo apsorbiralo se u Hetite i druge okolne narode, a njihovim se potomcima može smatrati Urartu čiji se jezik svrstava u istu porodicu huritsko-urartskih jezika. Hurite se ponekad povezuje s biblijskim Horitima iako takva veza nije znanstveno potvrđena.

Poveznice
 Hati
 Mitani
 Urartu

Literatura

Wikimedijski zajednički poslužitelj:

Nestali narodi
Stari narodi i civilizacije
Drevna Mezopotamija


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Glenea lunulata é uma espécie de escaravelho da família Cerambycidae. Foi descrita por Karl Jordan em 1894.

Referências

Borneo catalog 2005

lunulata
Coleópteros descritos em 1894


Among the commonest forms of SEO jobs being done today include the Site Index and HTML Coding. In fact, when a majority of SEO professionals often give a vent to their services they offer, it is interpreted that they are touching on a tiny set of methods that entail just only tweaking the website to ensure improved keyword rankings. Unfortunately, a first-rate search engine optimization program goes much ahead than these concerns. And, despite while it is necessary for any SEO professional to be well knowledgeable about these aspects and methods, it is imperative that anyone looking for optimization help to shop for an entire balance of SEO services.
On-page SEO is a dependable way to obtain enhanced visibility and rankings of a website with more traffic from search engines by revising HTML code and content.
In terms of on-page SEO, an ideal and affordable search engine optimization company will make effort to eliminate website prohibition and crack down on the indexing issues, which are stumbling blocks to your website's performance. It is imperative to keep in mind that these serve elementary elements to a concrete basis, but instead of on page SEO, off-page work is typically suggested once this stage is over.
Making sure the optimized pages of your website are stockpiled in the apt search engine deck is the main objective of on-page optimization. This technique is imperative to the thematic technique and will help you in learning how ably your website is ranked in the search engine result pages of Google. Methodically optimizing your website needs over simply suitable usage of keywords on-page SEO is a widespread plan, which entails the proficiencies of multiple website professionals in different domains.


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Stranger Aeons
About/Disclaimer
195 Metal Bands (Interviews): A Global Phenomenon
Tag Archives: Mark Lanegan
Sounds of the Underground #5
September 14, 2014 Guido Leave a comment
Time for some new revelations from the underground. I feel forced to not pick mysterious bands that no one has heard of this time, since there simply happen to be some brilliant bands I need to tell you about.
If you happen to have recommendations for me, they'd be most welcome. Leave me a comment!
Earth – Primitive and Deadly
Source: echoesanddust.com/
The band from Washington has been a defining and genre-shifting force for ages and thus already captivated my attention in the past. Particularly the album 'The Bees Made Honey in the Lion's Skull', from 2008, was amazing to me. Every album the band has produced since their conception in 1989 has been brilliant and different. This one has captivated me so much, that I'll go into every song for a bit.
Starting with "Torn By The Fox of the Crescent Moon", the cascading riffs wash down slowly but full of foreboding. The colour of the music indeed feels pale like the moon. Darkness is in the end the main element with which Earth is playing, but there's a light as well in that darkness, which is tangible in this songs beaming peaks that pierce the clouds. The description of a serpentine approach in music is embraced to the fullest in "There Is a Serpent Coming", which has some riffs that give the song a movie soundtrack quality. Mark Lanegan with his charcoal black rasp provides the repetitive vocals on this track, that is filled with anticipation and warning. Bleak sound is embraced by warmth in the voice and music, which leads to a magical musical experience.
"From the Zodiacal Light" features the warm and captivating vocals of Rabia Shaheen Qazi from the band Rose Windows. Though musically far distincts, the vocals show similarities with those of The Devil's Blood. Mystical words over soaring music and droning rhythm. Southern rock flavor is definitely detectable in the weeping guitar sounds of 'Even Hell Has Its Heroes'. The sound seems to slow down while the chords are reverberating in the air. It's the sound of the desert, with the sun shining in your eyes and twisting your vision, hallucinating and shrill sounding. The slow beat dragging on in the endless space around you. A similar sound can be heard on 'Rooks Across The Gates', featuring once again Mark Lanegan on vocal duties. This landscape is bleaker though and after almost ten minutes it just fades away.
Oh, check this interview by Steel for Brains with Dylan Carlson.
the xx – the xx / the xx – Coexist
When the debut of this band came out, I was very keen to get my hands on it and review their sounds. I thought it was beautiful, haunting, cool and the sound of a drive through a city in the very early morning or in the deep of the night. Recently I got back into the xx and decided to listen to that other album, which I sadly ignored at the time.
The hazy youthful sound of the debut already demonstrated something unique that probably would not be reproducable. The band was on that fragile moment between youth and adulthood, expressing the sublime angst of that point in an excellent album. That foggy, misty feeling of an early day, fresh and new, was captivated in the sounds on that first record.
That is the downfall of Coexist. Though it takes on the mellow beats, the minimal sound and gentle tones with whispered vocals, it lacks that fresh sound. The crisp break of dawn has been lifted and the monring sun has made the fog evaporate, it feels like a rehashed version of that moment when the fog was on the leaves and the cold was still in the air. When the words are whispered, no clouds appear from the mouth, just sounds. This time the angst is replaced by adulthood, certainty and a carreer. No longer is the magic in the air. It was a moment in time, that has now past. We still have the songs though.
Pallbearer – Foundations of Burden
source: Stereogum
The epic doom of Pallbearer is much appreciated in the world that adores it, so that makes it worth mentioning on itself. I like the epic quality of their sound, which reminds me a bit of Candlemass, even if it's only a feeling for me as a listener. The clean and strong vocals are a main reason for that opinion I would think.
Oh, the pallbearer is part of the ensemble that carries a coffin. That's kinda the drag they put in their doom, minor and sadness. It's really everything you could want from a doom record, including its accessability. This is easy going stuff, nothing harsh, just bleak and heavy as you would want it. If you are even slightly into doom and you love feeling a bit sad with some heavy, slow guitarwork, check this band out for real.
High point is in my opinion the song 'The Ghost I Used To Be'. Check it out. All crushing riffs, soaring guitars and picturesque vocals and strenght. Power metal meets doom? I don't know, but this song I love.
source: austin chronicle
Perfect Pussy – Say Yes To Love
What got me tuned in to the band Perfect Pussy was not their music, but their charming singer Meredith Graves. An interview passed around on UPcoming (with a tacky headline in that 'You won't believe'.. line they've been pumping out like there's no tomorrow), where she undressed while being interviewed. It was so captivating, that you forget that a beautiful lady is undressing. She spoke about punkrock, identity, looks and the self.
The music reflects that peculiar nature in a way I think. No distortion, just violent, wild passion is what the music expresses. An eclectic mixture of punkrock, noise and lofi rockmusic. The sound is energetic, uncompromising and light. The jangling guitar and the rattling drum form a warm tapestry of ragtag sound, that for some magical reason still sounds like a song.
Songs like 'Big Stars' and 'Dig' feature the almost proclaiming vocal style of Graves in their best shape. Powerful and relentless blurting out words of defiance. It is a great record and a great band that doesn't seem to have many problems being out there and against the norm.
cathedraldoomdroneEarthHardcoreMark LaneganMeredith Gravesmusicpallbearerperfect pussypunk
Welcome to Stranger Aeons. A blog about music, travels, opinions and other things that matter. All work is my own, if not I strive to mention it. These are stranger aeons we live in.
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The solo nestling in the hawk nest at the Cathedral of St. John the Divine is getting closer to fledging time, and that means some occasional wing flapping. Friday afternoon, shortly he'd shared a meal with mama, I caught a couple quick bursts.
But of course, there's plenty of sky-watching, preening and napping going on.
It looks to me a week or more before the hawk nestling is ready to fledge. That he's too young is obviously marked by the amount of fuzz still on his head, but you can also see that his tail feathers are much too short. But perhaps some time the first week of August.
Manhattan 2015 Nest Checklist Update 4
It's mid July, and all but one of Manhattan's baby red-tailed hawks have fledged from their nests. Some have even begun to successfully hunt for their own meals, or at least some of their meals.
Following is a list of the thirteen (13!) nests in Manhattan that this blog learned of, one of which we only found out about at the start of July. Twelve had hatches, with one of them on the second try of the season. A total of 26 baby hawks were observed in the nests. Of these, 24 have apparently fledged, one should fledge in about two weeks, and one died in the nest
The last nest to be noted, and which did not appear on any of the earlier checklist updates was at Grant's Tomb.
This is our fourth and last nest checklist update of the 2015 season. Background info about the twelve nests originally noted can be read here. Three previous updates appeared here (1), here (2), and here (3).
Hatched
Fledged
1. East Village/Ageloff Towers 3 3 First hatch about May 1. Two nestlings fledged June 20, third June 23.
2. NYU/Washington Square 2 2 Both eggs hatched by April 27. Fledged June 14 and 15.
3. Central Park Sheep Meadow 3 3 First hatch before May 9. First fledge June 23.
4. Fifth Ave. at 74th St. 3 3 First hatch about April 26. Two fledged June 13, third June 16.
5. CPW/Beresford Apts. No -- Failed.
6. West End Ave./80s 1 0 One baby died about June 10 before fledging.
7. St. John the Divine 1 -- First try failed. Egg in second clutch hatched about June 18-20; fledge expected first week of August.
8. Grant's Tomb 1 1 Hatch about May 18-20. Fledged early or fell from nest July 2 and was taken to wildlife rehab.
9. CCNY Shepard Hall 2 2? Hatch about April 18-20. Nest empty June 7; both nestlings presumably fledged.
10. Wright Park/Ft. Washington Ave. 3 3 Hatch about May 1-5. First fledge June 21/22; last about June 26.
11. Gorman Park/Fairview Ave. 3 3 Hatch about April 22-24. All nestlings fledged between June 7 and 14.
12. Highbridge Park/Swindler Cove 2 2? Hatch date unknown but guesstimated May 1-5. Nest empty June 27; both nestlings presumably fledged.
13. Inwood Hill Park 2 2 Hatch date unknown. Both nestlings reported fledged as of June 14.
7/17-7/18, St. John the Divine
The single baby hawk in the nest at the Cathedral of St. John the Divine is roughly four weeks old, so now has dark brown feathers covering his back and upper side of his wings. His head, though, is still fuzzy white and his breath is only just turning tawny.
Being a solo baby, he can sometimes be a little hard to find because he doesn't have to jostle with sibs for space and do a lot of excuse-me wing flapping. His preferred spot for perching seems to be toward the back of the nest, where he can't be seen from directly below the nest.
Friday and Saturday I had quick glimpses of the nestling. Early Friday evening he was peeking between the crenellations when I arrived.
But soon settled out of sight.
Mama Madeleine was also about, perched up atop the cathedral on Gabriel's horn, keeping an eye on things. I've seen her up there several times in the past two weeks, occasionally taking grief from the neighborhood kestrels.
Late Saturday afternoon I apparently arrived just about the time a feeding was ending. From the look of it, the hawk nestling might now be old enough to pull bits off of food off the meal himself.
Madeleine departed a minute later, heading north as she seems to do these days. The nestling poked around for another few minutes, providing a glimpse of growing feathers.
But then settled down at the back of the nest.
7/6, St. John the Divine
More observations from more hawkwatchers continue to indicate that there is probably just one baby in the red-tailed hawk nest at the Cathedral of St. John the Divine. But observers also seem to agree that it's a big baby. Perhaps being the only one, it's getting very well fed.
The nestling is now occasionally visible from below the nest along Morningside Drive if you find a good hole in the foliage.
Some spots are better than others.
At two weeks or even more, the baby doesn't need mama Madeleine to hang around the nest to keep him safe, but she was close by early Monday evening.
Preening and stretching.
Keeping an eye on the skies.
And dealing with harassment from one of the local kestrels.
It's July, so the kestrels will probably be in pesky mode for the next couple weeks.
7/4, Picnicking Hawks
Saturday evening at J. Hood Wright Park in Washington Heights, two of the red-tailed hawk fledglings decided to participate in the Independence Day picnicking happening around the park's central lawn. Lots of people came home from the park with hawk pictures, as the birds got right down with the people.
The first fledgling to be found was perched in a tree near the park's recreation center.
Something to the north catches his attention.
Very much has his attention. It's time to fly.
He flew north one tree, but was barely there before zoom, he and a second fledgling were flying to the other side of the lawn. And I could see movement at the top of a tree over there, too. Maybe an adult up there.
I located one of the fledglings perched low.
But he took off moments later, circled around and landed somewhere higher up and out of sight.
A minute or two later, one of the fledglings dropped down out of the sky and onto the ground.
Maybe a slightly higher vantage point would help.
Human picnickers began to gather. Who'd ever seen a hawk so close before?
Probably a good thing he doesn't know how to use that knife.
Or the tongs.
Too many people were edging in to take pix with their iPhones, and the fledge took off, heading for the trees over by the basketball courts.
But what about the other fledge, and what about the adult we saw?
There's mama at the very top of a tree.
The other fledge was trying to ease out onto the same clump of foliage as mama. She decided she wasn't having any of that and took off, heading east.
The fledging perched on the leaves for a few moments, and then did a parachute drop.
Pulling out of it just a few feet from the ground and then flying off toward the playground.
Took off again a few moments later and I lost track of him.
But wait, there's going to be more picnic action.
A couple minutes later, one of the fledglings landed on the lawn and started looking around.
What could he be looking for? Perhaps a pigeon that mama had dropped?
Right next to where a family was trying to enjoy their holiday meal.
The fledgling seemed to think it would be okay if he started to eat there, too.
But again, people started to close in to take pictures. Four or five bites and the fledgling began to think dinner might be better enjoyed with some privacy.
And zip, into the air and across the lawn, into the tree where I had first spotted one of the fledglings a half hour earlier.
Not entirely private up there, but certainly better than a moment ago.
Time for some chow.
The hawk fledgling's dinner was a good one, lasting well in excess of 20 minutes.
Nearing the end, he tried to gulp one of the largest remaining pieces.
Well, that wasn't going to work. Might as well spend a little more time on the meal.
7/3, Grant's Tomb Update
The grounded baby hawk rescued at Grant's Tomb last night is now spending some time with Wildlife In Need of Rescue and Rehabilitation. They report that, "He is basically starving at 575 grams, very thin. Other than being underweight, nothing else appears wrong at this time. ... He is too early to fledge judged by the length of his flight and tail feathers; he cannot get any height even if a healthy weight."
So although I had thought the bird might have fledged on Thursday and had a rough landing, it seems a bit more likely that he might have fallen from the nest. That he was found so close to the nesting site — which is located in the platform atop a metal pole close to the memorial retaining wall — also hints at a fall.
The baby red-tail being underweight suggests that there has been a problem with the parents feeding him, and that leads one to wonder if there has been conflict with the Riverside Church peregrine falcons just a block and a half down the street. Neither parent was to be seen in the area when I spent some time there Friday afternoon, nor was there any sign of another baby hawk in the nest.
If anyone has recent info about the adult red-tailed hawks at Grant's Tomb, please let us know.
7/2, Grant's Tomb
Late Thursday evening, I received a second-hand report of a baby hawk grounded near Grant's Tomb, on Riverside Drive at 122nd St. There'd been rumors about a possible red-tail nest in that area a couple months ago, but I'd heard nothing in quite a while. And with the falcons resident at Riverside Church just across the street, I'd always thought that was a terrible place for hawks.
Nevertheless...
It turns out there was indeed a red-tailed hawk fledgling at Grant's Tomb, with the nest being in a light or communications tower close to the memorial. Likely the young bird had fledged Thursday, had a rough landing, and was not able to get back up into a tree. Wildlife rehabbers will be checking him over on Friday, and if he proves healthy, he should be returned to his parents in a day or three.
A visit to the Cathedral of St. John the Divine early Thursday eve gave good looks at one nestling in the hawk nest. The young bird looks so big that a couple of us thought it could be two weeks old. That would match better (although not perfectly) with when I thought the second clutch of eggs were laid back in May.
In any event, the one nestling visible was lying high along the south side of the nest when I first arrived, but soon poked its head up and looked around.
Mama Madeleine, who had been lurking over on the hospital roof, flew up not long later, perching near the nest.
Soon enough she was down in the nest. She fussed about a bit but five minutes later, a feeding began.
After a few minutes Madeleine shifted to another position across the nest. She continued to feed the one nestling I could see but it's possible she was also feeding another, smaller one.
Eventually the child(ren) was fed and laid down for a nap. Madeleine had some morsels herself, and showed no inclination to leave right away.
Some nicer pictures and video of the scene can be seen on the Urban Hawks blog.


Since it was established in 1996, the Faculty of Media has worked to embody the philosophy of the university – to create synergies between the scientific theory and artistic experimentation – through, with and in media. The Bauhaus-Universität Weimar has demonstrated that media plays an increasingly significant role in the fields of science, art, society and business. By combining and integrating traditionally unrelated disciplines, the faculty strives to do justice to the complexity of its subject of study.
The faculty is divided into three main departments – Computer Science, Media Studies and Media Management – comprised of 16 full chairs and 5 junior chairs which are systematically interconnected with one another. Together with their students, they regularly develop excellent and creative approaches, characterised by experimental working methods and curiosity-driven research. The faculty's researchers and instructors are devoted to sustainably supporting and promoting these activities.
All the media degree programmes in Weimar are characterised by a well-supervised research environment, unrestricted creativity and experimentation in excellently equipped laboratories and workshops. The Faculty of Media is unlike any other in Germany; our academic and professional competence is concentrated in eight degree programmes which enable students to pursue their interests and take advantage of their personal talents in an independent and interdisciplinary manner. In this way, we do our part to foster the spirit of the university: Experiment Bauhaus!
The dynamic environment at our faculty encourages personal initiative and commitment in its students and prepares them to become creative and academic media professionals. Project-oriented study in small teams and personal contact to one's instructors provide the optimal conditions for putting one's practical skills to the test. Our focus is not only on allowing students to use what they have learned, but also teaching them to independently and critically question conventional knowledge. And throughout their entire education, our students are encouraged to look beyond their subject of study and take advantage of the courses offered by other degree programmes and faculties.
The international character of the Faculty of Media features a wide range of courses and events that are held in English and French, as well as an intensive promotion of the cooperation with universities abroad. Since 1998, the faculty has successfully offered the study program »European Media Culture« in collaboration with the Université Lumière Lyon 2. At the faculty's Department of Computer Science, prospective students can choose among three master programs completely held in English which include the M. Sc. program »Digital Engineering« that has been offered since 2017 in collaboration with the faculty of Civil Engineering. In this manner, the Faculty of Media promotes the international exchange among students and prepares them optimally for nowadays global job market.


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New Treatment for Alzheimer's and Huntington's Diseases
Relies on Addressing the Beta-Amyloid Pathway.
Comments by J. C. Spencer
Ridding the brain of toxic amyloid plaques is viewed as a key target in slowing the course of Alzheimer's disease. The amyloid pathway is THE MAIN HALLMARK OF ALZHEIMER'S DISEASE. Here are two articles that deal with Alzheimer's, Huntington's, and the beta-amyloid pathway. WHATEVER WORKS is what families with Alzheimer's or Huntington's members want to see. Research has concluded what the problem is. Throwing billions of dollars at the problem may not be the solution, but scientists are trying. Part of the problem is that every drug, regardless of the hope it may help, adds more toxins to the body.
Meanwhile, I suggest we look further at cutting healthcare costs by switching out regular sugar with a glyconutrient called trehalose. The first article below is about GSK paying $28.5 million up front for a vaccine deal that may help address the beta-amyloid challenge. The second article is an abstract from a published paper showing that the sugar trehalose may hold the answer for Alzheimer's and Huntington's disease by addressing the beta-amyloid challenge.
GSK Pays Affiris $28M Up Front in Alzheimer's Vaccine Deal
(BioWorld Today Via Acquire Media NewsEdge) GlaxoSmithKline Biologicals SA, of Rixensart, Belgium, and Affiris GmbH entered a collaboration agreement granting GSK exclusive rights to Affiris's Alzheimer's disease vaccine programs targeting the beta-amyloid pathway.
Under the terms, Vienna, Austria-based Affiris will receive an up-front payment of 22.5 million (US$28.5 million) and could be eligible for future milestone payments and royalties. The total potential value of the agreement could reach 430 million in the event of full commercial success of the candidate vaccines.
As part of the deal, GSK is acquiring exclusive rights to develop and commercialize two Alzheimer's disease vaccine candidates that are based on Affiris' Affitope technology and are in Phase I development. Affiris also is granting GSK an exclusive option to develop and commercialize alternative Alzheimer's disease vaccine candidates, which are in preclinical development. The agreement is subject to government approval, GSK said.
Ridding the brain of toxic amyloid plaques is viewed as a key target in slowing the course of Alzheimer's disease. As GSK spokeswoman Sarah Alspach put it, the amyloid pathway is "the main hallmark of Alzheimer's disease," and thus an attractive target for new therapeutic approaches.
Nitasha Manchanda, an analyst with Decision Resources, offered a more tempered view, saying it's "still not really clear if this is the best target." But it's also "too early to rule this out as a significant approach," she told BioWorld Today.
Although amyloid remains a highly touted drug target for Alzheimer's disease, it has shown lackluster results in some recent studies, including a Phase III trial of Salt Lake City-based Myriad Genetics Inc.'s Flurizan; a Phase II study of bapineuzumab (AAb-001) from partners Dublin, Ireland-based Elan Corp. plc, and Madison, N.J.-based Wyeth; and a Phase III study of Alzhemed from Canadian firm Neurochem Inc. (See BioWorld Today, Aug. 28, 2007, July 31, 2008, and Aug. 21, 2008.)
Despite those recent setbacks, pharma companies continue to show interest in a range of approaches to fighting Alzheimer's. For example, Pfizer Inc. recently paid $225 million up front to Medivation Inc. to co-develop and market Dimebon, the biotech company's experimental drug for Alzheimer's and Huntington's disease. Dimebon (dimebolin) is believed to work by improving the mitochondrial function impaired in Alzheimer's disease. (See BioWorld Today, July 31, 2008, and Sept. 4, 2008.)
In August, German drugmaker Boehringer Ingelheim GmbH and Belgium's Ablynx NV extended their Alzheimer's drug development collaboration for another year. Boehringer also signed a deal with Evotec AG, of Hamburg, Germany, to jointly identify new targets in the treatment of Alzheimer's.
Earlier this year, CoMentis Inc. entered a $760 million deal with Japan's Astellas Pharma Inc. to develop a compound for Alzheimer's. And another Japanese drugmaker, Eisai Co. Ltd., has extended a 2007 deal with TorreyPines Therapeutics Inc., to discover targets for the disease.
In a 2007 deal with Coley Pharmaceutical Group Inc., Merck & Co. paid $4 million up front for rights to Coley's VaxImmune technology for use in developing vaccines for infectious disease and Alzheimer's.
Elan and Wyeth's ACC001 is the furthest ahead among those pursuing an immune therapy for Alzheimer's disease, Manchanda said. But that program is an active vaccine, and it is unclear whether an active antibody would have a longer-lasting effect, she added.
That could be a problem if the therapy causes an adverse reaction, and treatment needs to be stopped.
In contrast, Manchanda said that passive vaccines like those being developed by Affiris would have to be reinjected in patients to keep beta-amyloid at bay. Thus, the passive vaccine might be safer than active, because if a patient shows a reaction, treatment could be stopped, she explained.
Clinical trials of Elan's and Wyeth's AN-1792, a synthetic form of the beta-amyloid peptide, were suspended in 2002 when clinical signs consistent with encephalitis were reported in four patients. Development of the companies' ACC-011 Alzheimer's vaccine was halted due to a patient developing skin lesions, identified as a suspected case of vasculitis (inflammation of blood vessels), though the study later was restarted. (See BioWorld Today, April 21, 2008.)
While various other therapeutic approaches are being pursued in Alzheimer's disease such as tau-based programs, Manchanda said she believes that amyloid may be "the best bet" for pharmaceutical companies looking for potential new Alzheimer's drugs. Tau-based programs, such as those from TauRx Therapeutics Ltd. and Allon Therapeutics Inc., are in earlier stages and it will be a while before they reach the pivotal stage, she said.
Other therapies, like Medivations' Dimebon, are being developed to improve cognition but may not address the underlying disease, Manchanda said.
Still other firms like Winston-Salem, N.C.-based Targacept Inc. and London-based AstraZeneca plc each have products in development whose functions are similar to those of approved cholinesterase inhibitors but target different brain receptors.
Alzheimer's disease affects more than 26 million people worldwide, creating a $4 billion market.
Currently available drugs - Aricept (donepezil, Pfizer), Exelon (rivastigmine, Novartis AG), Cognex (tacrine, First Horizon Pharmaceutical Corp.), Reminyl (galantamine, Shire Pharmaceuticals Group plc) and Namenda (memantine, Forest Laboratories Inc.) - boost memory and cognition but cannot slow the course of the disease.
http://www.tmcnet.com/usubmit/-gsk-pays-affiris-28m-up-front-alzheimers-vaccine-/2008/10/24/3731992.htm
Trehalose differentially inhibits aggregation and neurotoxicity of beta-amyloid 40 and 42.
Liu R, Barkhordarian H, Emadi S, Park CB, Sierks MR.
Department of Chemical and Materials Engineering, Arizona State University, Box 876006, Tempe, AZ 85287-6006, USA.
A key event in Alzheimer's disease (AD) pathogenesis is the conversion of the peptide beta-amyloid (Abeta) from its soluble monomeric form into various aggregated morphologies in the brain. Preventing aggregation of Abeta is being actively pursued as a primary therapeutic strategy for treating AD.
Trehalose, a simple disaccharide, has been shown to be effective in preventing the deactivation of numerous proteins and in protecting cells against stress. Here, we show that trehalose is also effective in inhibiting aggregation of Abeta and reducing its cytotoxicity, although it shows differential effects toward Abeta40 and Abeta42. When co-incubated with Abeta40, trehalose inhibits formation of both fibrillar and oligomeric morphologies as determined by fluorescence staining and atomic force microscopy (AFM). However, when co-incubated with Abeta42, trehalose inhibits formation only of the fibrillar morphology, with significant oligomeric formation still present. When aggregated mixtures were incubated with SH-SY5Y cells, trehalose was shown to reduce the toxicity of Abeta40 mixtures, but not Abeta42.
These results provide additional evidence that aggregation of Abeta into soluble oligomeric forms is a pathological step in AD and that Abeta42 in particular is more susceptible to forming these toxic oligomers than Abeta40. These results also suggest that the use of trehalose, a highly soluble, low-priced sugar, as part of a potential therapeutic cocktail to control Abeta peptide aggregation and toxicity, warrants further study.
Last Updated ( Dec 02, 2008 at 11:22 AM )


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Art Quiz: The Answer is Futurism
Judith March 1, 2022 February 25, 2022 Abstract Art, Art History, Art Quiz, Elements of Art, Famous Artists, Famous Works of Art
Art in early 20th century Italy was centered around the past. The atmosphere must have felt stifling and oppressive to those with creative spirits. One such individual was Italian poet Filippo Tommaso Marinetti. In 1908 he began working on a declaration — which was first published as a preface to a volume of poetry in January of the following year. It's quite an interesting document to read.
Later, his "Manifesto of Futurism" was published in Paris newspapers, expressing his concept of "a new beauty". Wikipedia says:
The Manifesto of Futurism … expresses an artistic philosophy called Futurism that was a rejection of the past and a celebration of speed, machinery, violence, youth, and industry. It also advocated the modernization and cultural rejuvenation of Italy.
You can, if you wish, read the complete manifesto here, or you might choose instead to watch this fun little animated video that presents it in quite an amusing way.
Another fun film clip comes from Curious Muse:
While "futurism" may have begun in literary circles, it spread into the world of visual arts. Part of its intent was to "shock" people, to be scandalous. After one of Marinetti's stage productions was ridiculed, he added provisions that futuristic works should be heckled and criticized.
As an "art form", futurism led to much performance art complete with "modernistic" costumes, as well as to much colorful, almost abstract art. It's all about speed, energy, machinery, and the world moving forward.
Below is "Dynamism of a Cyclist" by Umberto Boccioni. I love the brightness and the real sense of "dynamism" I feel when I view this oil painting.
Another of his works, The City Rises, painted in 1910, also caught my eye as I browsed about the Internet to learn more about futurism.
Another futuristic artist was Giacomo Ball. Here is one of his works — The Car Has Passed
And from Gino Severini we have Suburban Train Arriving in Paris:
Art historians believe it's difficult for us today to fully understand and appreciate the futurist movement. We are quite accustomed to machinery, robots, technology, and a "need for speed" — so much so that there's even a video game based on the latter. That's technology meeting technology, I suppose. The point is, we don't see these new-fangled ideas as revolutionary, world-changing, or note-worthy. We simply accept them and move on with our lives.
But imagine how different the world was in early 20th century Italy. Imagine buildings going up, machinery running, gears grinding, trains rolling across the countryside, and even automobiles carrying people quickly to their destinations. Oh, what mind-boggling achievements those surely must have seemed.
I do like this futurist art now that I've learned about it. I think I most love the energy I feel in each of the paintings shown above. Yet while it's interesting, I wouldn't want to be around too much of it, or spend too much time with it. It's a bit too energetic, perhaps.
It's much like visiting New York City. It's filled with energy. You can feel it all around you; you can breathe it in the air. And, you know that old saying about New York City: It's a nice place to visit, but you wouldn't want to live there.
That's my feeling about futurism. I love "visiting" these paintings, reading about the crazy "art" performances that came out of this movement, and getting acquainted with the founders, but a little goes a long way for me. I wouldn't want to live in a fast-paced, futuristic world, at least not without places I can retreat to, gentle scenes that soothe me, and colors of a slightly more peaceful palette.
Declaration of Futurism, Fillipo Tommaso Marinetti, Futurism, Futurism Manifesto, Giacomo Bella, Gino Severini, Umberto Boccioni
Previous Art Quiz: Question 43
Next "This Above All, To Thine Own Self Be True"
musingsofanepeolator says:
I absolutely loved going through your meticulous observation on Futurism. Thanks for this informational post.
I'm glad you liked it. Did you watch either of the videos? I thought they were both quite interesting and informative.
Reblogged this on Devyani's World of Epeolatry and Bibliophilia.
Thanks for the share.
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