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A rich history of innovation
A rich history of innovation Corning Incorporated is the world leader in speciality glass and ceramics, drawing on more than…
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The Google Apps for Education European User Group (GEUG14), taking place at the Ron Cooke Hub between 23–24 June, aims…
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Are cashless campuses the future?
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Managing a child's online journey
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Four pupils from the Grimsby Institute of Further & Higher Education have been crowned the new Cyber Security Challenge Schools…
Make the world want your website
Torchbox recently launched sites with two of the UK's most exciting universities: the Royal College of Art (RCA), often described…
UB July edition out now
The latest issue of University Business includes all the latest news and views from the higher education sector. Including a…
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Innovation in IT networks
How to stand out from the crowd
February 10, 11am (GMT)


So as you know we currently rent our condo, it is an older condo which means more room but less efficient. This winter was a LOT colder than last year for sure, which meant that even if our heater was going all the time and using the really expensive auxiliary heating coils, it wouldn't get above 66 in our place. Which can be frustrating when we still pay a lot in utilities,but that is something that you just have to come to terms with when renting. One day we look forward to having a house, just so that if there is something wrong with insulations, windows, doors, heaters, etc. we can actually get those things fixed and changed over time.Our biggest problem right now is the windows in our condo, some of the double paned areas have fog on the inside and you can feel how drafty they are. They sell a lot of kits you can use for covering the windows with plastic wrap,but they all entail adhering the plastic to the window, wall, or frame around the window. We aren't allowed to attach anything like that or make holes in our walls, so those weren't options for us. Also, each window has the blinds hung differently. Some are right up against the windows, some are a few inches away from the window it self, and some have a lot of space where they are flush with the wall. This meant that we would most likely have to take the blinds down before being able to insulate the windows which we aren't supposed to do either. After much thought we came up with an option that would work.
We bought  screws and wood from Home Depot, trying to the straighter and less knotty ones. We bought shims too,but ended up not needing them and returning them.
We then measured each window and cut all of the pieces to size and made a mess.
Each window is different so we made a frame for each one.
We then used our industrial Saran wrap.
This window had the blinds against the window so that made it nice, some of the others we had to notch the top so we could fit these frames behind the blinds.
We had to make the frames free standing so that they just slid into the opening and could be taken out again without damaging the windows and frames at all.
Putting the Saran Wrap on was a two person job, but we got it done in the end, but you can see this way there is air trapped in between the wrap to help insulate more.
Here you can see one of the finished frames, this one bowed in the top left which we need to fix because the saran wrap put too much pressure on the knot there. We did a total of 4 large frames in our whole condo and it has made a huge difference. They don't look very pretty, but we can take them down if we need to at any time. Home Depot sells a dark colored Sheet insulation that probably would have done a better job than these frames and would have been easier to make,but we wanted natural light to enter into our place. So, a little ghetto,but for just the winter months we are happier with these than without them.


I've just about wrapped up the site design and have a few things left. If anyone finds anything odd, please leave a comment. My housekeeping list for the site is as follows: correct rounded corner above footer (IE), modify and style <code> tag, modify and style upper navigation (to identify current page), insert content for upper navigation, insert content for footer disclaimer, style comment entry window, test inline images on articles, check site for validation, clean up admin and css files.
I finally have some free time to work on the site layout. Little did I know that after my last post about having a bug, I would get a bug - the flu. So I'm wasting the time away in front of the computer at home instead of at work. Things may get crazy looking on the site, but they will be corrected shortly. And I know, I should be working on a development version of the site and not the live one, but it's easier this way.
Dude, I'm not Getting a Dell?
I purchased my current desktop computer from Dell. I thought I got a pretty good deal with the $150 mail in rebate, DVD Burner upgrade and upgrades to the RAM and hard drive. This time around I tried a different approach. Instead of ordering online I decided to make some phone calls and, to my surprise, I won't be getting a Dell after all. Not considering the dinosaurs the likes of the TRS-80 and Apple IIC, I'll be going back to my PC roots and getting a Gateway. So how much did I save?
Running some numbers by ordering over the phone, I saved about $700 from Gateway. By comparison if I ordered the same Duo-Core laptop models from Dell or Apple it would have cost me $800 and $1000 more, respectively. So how much did I pay? I got a top of the line Duo-Core for a bottom line of $1600. This includes all tax and delivery charges as well as upgrades to the hard drive, video card, optical drive, RAM, processor and screen. So what did I do that go me such a deal? I told them I was going to buy a laptop in the next 24 hours and if they gave me the best deal I would do business with them. I made a few calls and played their sales game telling them I'd call them back and I'd have to crunch some numbers. In the end I'd like to think I beat the salesman at his own game. Either way, I'm getting a Gateway, moo!
I recently got a friend of mine a job with the company that employs me. I always thought he may be emotionally imbalanced, but didn't make much of it especially since he has a solid skill set and would be a great asset to our Web team. After giving him enough interview tips to get a mongoloid hired as an engineer at Google, he's in; without a face-to-face interview. Not only is he in, but he's in big; making triple what he did with his previous employer.
Shortly after starting, I begin to take notice of his paranoid, reclusive and socially-immature personality. I won't get into details, but it's gotten so bad that he doesn't even trust me, even though I got him hired (though I'm sure somewhere in his delusional mind thinks he got the job on his own merit). I'm not expecting him to crown me dictator, but put away your knife show me some respect. Never again will I ignore the facts, especially if the writing's on the walls.
Finally, after all this time I'm ready to start posting! I've got a few layout and style issues I need to iron out in the CSS, but I figured it shouldn't stop me from getting started. Major site additions are on the way.


Have a planned vacation in Stockholm for New Year's? Lucky you! It's a wonderful time to be in the city. If you want to know where to go to look at fireworks, you've come to the right place! All of these are for free.
Stockholm is a city built on 14 islands, which means that there 1. are plenty of water surrounding the city, great for reflections and 2. a lot of heights and hills. Here's our favourite spots for watching fire-works.
Fjällgatan is a classic when it comes to watching the fireworks in Stockholm. With it's magnificent view over the waterfront of Stockholm, including Gamla stan and Skeppsholmen, you'll see everything there is to see.
Skinnarviksberget is from where the photo above is taken. This hill/mountain shows you Kungsholmen, the City Hall and Riddarholmen. As if the photo hadn't convinced you yet.
Västerbron might be a bit unconventional as it's a bridge, but the thing is that this bridge is one of the highest points in the city AND it has views in two directions.
Slussen is also one of those super popular places, however it might be different during the construction of new Slussen.


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Microarray Analysis of Lymphatic Tissue Reveals Stage-Specific, Gene-Expression Signatures in HIV-1 Infection
ABSTRACT: Untreated HIV-1 infection progresses through acute and asymptomatic stages to AIDS. While each of the three stages has well-known clinical, virologic and immunological characteristics, much less is known of the molecular mechanisms underlying each stage. Here we report lymphatic tissue microarray analyses revealing for the first time stage-specific patterns of gene expression during HIV-1 infection. We show that while there is a common set of key genes with altered expression throughout all stages, each stage has a unique gene-expression signature. The acute stage is most notably characterized by increased expression of hundreds of genes involved in immune activation, innate immune defenses (e.g.MDA-5, TLR-7 and -8, PKR, APOBEC3B, 3F, 3G), adaptive immunity, and in the pro-apoptotic Fas-Fas-L pathway. Yet, quite strikingly, the expression of nearly all acute-stage genes return to baseline levels in the asymptomatic stage, accompanying partial control of infection. In the AIDS stage, decreased expression of numerous genes involved in T cell signaling identifies genes contributing to T cell dysfunction. These common and stage-specific, gene-expression signatures provide new insights into the molecular mechanisms underlying the host response and the slow, natural course of HIV-1 infection. Overall design: A total of 52 patients were analyzed: 10 patients unaffected, 18 patients with asymptomatic stages of AIDs, 16 patients with acute stages of AIDs, and 8 patients with AIDs.
REANALYSED by: GSE119128
INSTRUMENT(S): [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
SUBMITTER: qingsheng li
Transcription profiling by array of human lymphatic tissue from HIV-1 infected individuals
Project description:Untreated HIV-1 infection progresses through acute and asymptomatic stages to AIDS. While each of the three stages has well-known clinical, virologic and immunological characteristics, much less is known of the molecular mechanisms underlying each stage. Here we report lymphatic tissue microarray analyses revealing for the first time stage-specific patterns of gene expression during HIV-1 infection. We show that while there is a common set of key genes with altered expression throughout all stages, each stage has a unique gene-expression signature. The acute stage is most notably characterized by increased expression of hundreds of genes involved in immune activation, innate immune defenses (e.g.MDA-5, TLR-7 and -8, PKR, APOBEC3B, 3F, 3G), adaptive immunity, and in the pro-apoptotic Fas-Fas-L pathway. Yet, quite strikingly, the expression of nearly all acute-stage genes return to baseline levels in the asymptomatic stage, accompanying partial control of infection. In the AIDS stage, decreased expression of numerous genes involved in T cell signaling identifies genes contributing to T cell dysfunction. These common and stage-specific, gene-expression signatures provide new insights into the molecular mechanisms underlying the host response and the slow, natural course of HIV-1 infection. Experiment Overall Design: A total of 52 patients were analyzed: 10 patients unaffected, 18 patients with asymptomatic stages of AIDs, 16 patients with acute stages of AIDs, and 8 patients with AIDs.
Vanee2010 - Genome-scale metabolic model of Cryptosporidium hominis (iNV213)
Project description:Vanee2010 - Genome-scale metabolic model of Cryptosporidium hominis (iNV213) This model is described in the article: A genome-scale metabolic model of Cryptosporidium hominis. Vanee N, Roberts SB, Fong SS, Manque P, Buck GA. Chem. Biodivers. 2010 May; 7(5): 1026-1039 Abstract: The apicomplexan Cryptosporidium is a protozoan parasite of humans and other mammals. Cryptosporidium species cause acute gastroenteritis and diarrheal disease in healthy humans and animals, and cause life-threatening infection in immunocompromised individuals such as people with AIDS. The parasite has a one-host life cycle and commonly invades intestinal epithelial cells. The current genome annotation of C. hominis, the most serious human pathogen, predicts 3884 genes of which ca. 1581 have predicted functional annotations. Using a combination of bioinformatics analysis, biochemical evidence, and high-throughput data, we have constructed a genome-scale metabolic model of C. hominis. The model is comprised of 213 gene-associated enzymes involved in 540 reactions among the major metabolic pathways and provides a link between the genotype and the phenotype of the organism, making it possible to study and predict behavior based upon genome content. This model was also used to analyze the two life stages of the parasite by integrating the stage-specific proteomic data for oocyst and sporozoite stages. Overall, this model provides a computational framework to systematically study and analyze various functional behaviors of C. hominis with respect to its life cycle and pathogenicity. This model is hosted on BioModels Database and identified by: MODEL1507180071. To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.
2015-07-30 | MODEL1507180071 | BioModels
Circulating Monocytes in HIV-1 infected Viremic Subjects Exhibit an Anti-Apoptotic Gene Signature
Project description:Mechanisms that may allow circulating monocytes to persist as CD4 T cells diminish in HIV-1 infection have not been investigated. We have characterized steady-state gene expression signatures in circulating monocytes from HIV-infected subjects and have identified a stable anti-apoptosis gene signature comprised of 38 genes associated with p53, CD40L, TNF and MAPKinase signaling networks. The significance of this gene signature is indicated by our demonstration of cadmium chloride- or Fas ligand-induced apoptosis resistance in circulating monocytes in contrast to increasing apoptosis in CD4 T cells from the same infected subjects. As potential mechanisms in vivo, we show that monocyte CCR5 binding by HIV-1 virus or agonist chemokines serve as independent viral and host modulators resulting in increased monocyte apoptosis resistance in vitro. We also show evidence for concordance between circulating monocyte apoptosis-related gene expression in HIV-1 infection in vivo and available datasets following viral infection or envelope exposure in monocyte derived macrophages in vitro. The identification of in vivo gene expression associated with monocyte resistance to apoptosis is of relevance to AIDS pathogenesis since it would contribute to: (1) maintaining viability of infection targets and long-term reservoirs of HIV-1 infection in the monocyte/macrophage populations, and (2) protecting a cell subset critical to host survival in spite of sustained high viral replication. Keywords: two group study design Overall design: 33 samples hybridized, including 13 HIV-1 Patients, 12 Healthy Controls and 4 HIV-1 Patients and 4 Controls followed 6 months later
Revilla2003 - Controlling HIV infection using recombinant viruses
Project description:This a model from the article: Fighting a virus with a virus: a dynamic model for HIV-1 therapy. Revilla T, Garcia-Ramos G. Math Biosci 2003 Oct;185(2):191-203 12941536 , Abstract: A mathematical model examined a potential therapy for controlling viral infections using genetically modified viruses. The control of the infection is an indirect effect of the selective elimination by an engineered virus of infected cells that are the source of the pathogens. Therefore, this engineered virus could greatly compensate for a dysfunctional immune system compromised by AIDS. In vitro studies using engineered viruses have been shown to decrease the HIV-1 load about 1000-fold. However, the efficacy of this potential treatment for reducing the viral load in AIDS patients is unknown. The present model studied the interactions among the HIV-1 virus, its main host cell (activated CD4+ T cells), and a therapeutic engineered virus in an in vivo context; and it examined the conditions for controlling the pathogen. This model predicted a significant drop in the HIV-1 load, but the treatment does not eradicate HIV. A basic estimation using a currently engineered virus indicated an HIV-1 load reduction of 92% and a recovery of host cells to 17% of their normal level. Greater success (98% HIV reduction, 44% host cells recovery) is expected as more competent engineered viruses are designed. These results suggest that therapy using viruses could be an alternative to extend the survival of AIDS patients. This model was taken from the CellML repository and automatically converted to SBML. The original model was: Revilla T, Garcia-Ramos G. (2003) - version=1.0 The original CellML model was created by: Catherine Lloyd c.lloyd@auckland.ac.nz The University of Auckland This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
2018-08-29 | BIOMD0000000707 | BioModels
Project description:Mechanisms that may allow circulating monocytes to persist as CD4 T cells diminish in HIV-1 infection have not been investigated. We have characterized steady-state gene expression signatures in circulating monocytes from HIV-infected subjects and have identified a stable anti-apoptosis gene signature comprised of 38 genes associated with p53, CD40L, TNF and MAPKinase signaling networks. The significance of this gene signature is indicated by our demonstration of cadmium chloride- or Fas ligand-induced apoptosis resistance in circulating monocytes in contrast to increasing apoptosis in CD4 T cells from the same infected subjects. As potential mechanisms in vivo, we show that monocyte CCR5 binding by HIV-1 virus or agonist chemokines serve as independent viral and host modulators resulting in increased monocyte apoptosis resistance in vitro. We also show evidence for concordance between circulating monocyte apoptosis-related gene expression in HIV-1 infection in vivo and available datasets following viral infection or envelope exposure in monocyte derived macrophages in vitro. The identification of in vivo gene expression associated with monocyte resistance to apoptosis is of relevance to AIDS pathogenesis since it would contribute to: (1) maintaining viability of infection targets and long-term reservoirs of HIV-1 infection in the monocyte/macrophage populations, and (2) protecting a cell subset critical to host survival in spite of sustained high viral replication. Keywords: two group study design 33 samples hybridized, including 13 HIV-1 Patients, 12 Healthy Controls and 4 HIV-1 Patients and 4 Controls followed 6 months later
Nelson1995_HIV1therapy_DIVadministraion_ModelA
Project description:This a model from the article: Modeling defective interfering virus therapy for AIDS: conditions for DIV survival. Nelson GW, Perelson AS. Math Biosci 1995 Feb;125(2):127-53 7881191 , Abstract: The administration of a genetically engineered defective interfering virus (DIV) that interferes with HIV-1 replication has been proposed as a therapy for HIV-1 infection and AIDS. The proposed interfering virus, which is designed to superinfect HIV-1 infected cells, carries ribozymes that cleave conserved regions in HIV-1 RNA that code for the viral envelope protein. Thus DIV infection of HIV-1 infected cells should reduce or eliminate viral production by these cells. The success of this therapeutic strategy will depend both on the intercellular interaction of DIV and HIV-1, and on the overall dynamics of virus and T cells in the body. To study these dynamical issues, we have constructed a mathematical model of the interaction of HIV-1, DIV, and CD4+ cells in vivo. The results of both mathematical analysis and numerical simulation indicate that survival of the engineered DIV purely on a peripheral blood HIV-1 infection is unlikely. However, analytical results indicate that DIV might well survive on HIV-1 infected CD4+ cells in lymphoid organs such as lymph nodes and spleen, or on other HIV-1 infected cells in these organs. This model was taken from the CellML repository and automatically converted to SBML. The original model was: Nelson GW, Perelson AS. (1995) - version=1.0 The original CellML model was created by: Ethan Choi mcho099@aucklanduni.ac.nz The University of Auckland This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
Nelson1995_HIV1therapy_DIVadministraion_ModelB
Wodarz2007 - HIV/CD4 T-cell interaction
Project description:Wodarz2007 - HIV/CD4 T-cell interaction A deterministic model illustrating how CD4 T-cells can influence HIV infection. This model is described in the article: Infection dynamics in HIV-specific CD4 T cells: does a CD4 T cell boost benefit the host or the virus? Wodarz D, Hamer DH. Math Biosci 2007 Sep; 209(1): 14-29 Abstract: Recent experimental data have shown that HIV-specific CD4 T cells provide a very important target for HIV replication. We use mathematical models to explore the effect of specific CD4 T cell infection on the dynamics of virus spread and immune responses. Infected CD4 T cells can provide antigen for their own stimulation. We show that such autocatalytic cell division can significantly enhance virus spread, and can also provide an additional reservoir for virus persistence during anti-viral drug therapy. In addition, the initial number of HIV-specific CD4 T cells is an important determinant of acute infection dynamics. A high initial number of HIV-specific CD4 T cells can lead to a sudden and fast drop of the population of HIV-specific CD4 T cells which results quickly in their extinction. On the other hand, a low initial number of HIV-specific CD4 T cells can lead to a prolonged persistence of HIV-specific CD4 T cell help at higher levels. The model suggests that boosting the population of HIV-specific CD4 T cells can increase the amount of virus-induced immune impairment, lead to less efficient anti-viral effector responses, and thus speed up disease progression, especially if effector responses such as CTL have not been sufficiently boosted at the same time. This model is hosted on BioModels Database and identified by: BIOMD0000000663. To cite BioModels Database, please use: Chelliah V et al. BioModels: ten-year anniversary. Nucl. Acids Res. 2015, 43(Database issue):D542-8. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.
AIDS-related Kaposi's sarcoma
Project description:Kaposi's Sarcoma (KS) is a proliferation of aberrant vascular structures lined by spindle cells, and is caused by a gammaherpes virus (HHV8/KSHV). Its course is aggravated by co-infection with HIV-1, where the timing of infection with HIV-1 and HHV8 is important for the clinical outcome. METHODS: In order to better understand the pathogenesis of KS, we have analysed tissue from two AIDS-KS lesions, and from normal skin by serial analysis of gene expression (SAGE). Semi-quantitative RT-PCR was then used to validate the results. RESULTS: The expression profile of AIDS-related KS (AIDS-KS) reflects an active process in the skin. Transcripts of HHV8 were found to be very low, and HIV-1 mRNA was not detected by SAGE, although it could be found using RT-PCR. Comparing the expression profile of AIDS-KS tissue with publicly available SAGE libraries suggested that AIDS-KS mRNA levels are most similar to those in an artificially mixed library of endothelial cells and leukocytes, in line with the description of KS lesions as containing spindle cells with endothelial characteristics, and an inflammatory infiltrate. At least 64 transcripts were found to be significantly elevated, and 28 were statistically downregulated in AIDS-KS compared to normal skin. Five of the upregulated mRNAs, including Tie 1 and sialoadhesin/CD169, were confirmed by semi-quantitative PCR to be elevated in additional AIDS-KS biopsies. Antibodies to sialoadhesin/CD169, a known marker of activated macrophages, were shown to specifically label tumour macrophages. CONCLUSION: The expression profile of AIDS-KS showed 64 genes to be significantly upregulated, and 28 genes downregulated, compared with normal skin. One of the genes with increased expression was sialoadhesin (CD169). Antibodies to sialoadhesin/CD169 specifically labelled tumour-associated macrophages, suggesting that macrophages present in AIDS-KS lesions belong to a subset of human CD169+ macrophages. Keywords: other
2003-07-16 | GSE514 | GEO
Long-term Antiretroviral Treatment Initiated in Primary HIV-1 Infection Affects the Size, Composition and Decay Kinetics of the Reservoir of HIV-1 Infected CD4 T Cells
Project description:Initiation of antiretroviral therapy during the earliest stages of HIV-1 infection may limit the seeding of a long-lasting viral reservoir, but long-term effects of early antiretroviral treatment initiation remain unknown. Here, we analyzed immunological and virological characteristics of nine patients who started antiretroviral therapy in primary HIV-1 infection and remained on suppressive treatment for >10 years; patients with similar treatment duration but initiation of therapy in chronic HIV-1 infection served as controls. We observed that independently of the timing of treatment initiation, HIV-1 DNA in CD4 T cells decayed exclusively during the initial 3-4 years of treatment; however, in patients who started antiretroviral therapy in acute infection, this decay occurred faster and was more pronounced, leading to substantially lower levels of cell-associated HIV-1 DNA after long-term treatment. Despite this smaller size, the viral CD4 T cell reservoir in persons with early treatment initiation consisted more dominantly of the long-lasting central-memory and T memory stem cells. Moreover, gene transcripts in CD4 T cells associated with the total viral CD4 T cell reservoir size frequently correlated with the relative proportion of these long-lived CD4 T cell subsets, suggesting shared gene expression signatures for maintaining HIV-1 persistence and preservation of long-lasting CD4 T cell subsets. Despite effective suppression of viral antigens for >10 years, HIV-1-specific T cell responses remained continuously detectable in both study groups. Together, these data suggest that although early HIV-1 treatment initiation, even when continued for >10 years, is unlikely to lead to viral eradication, the presence of low viral reservoirs and durable HIV-1 T cell responses may make such patients attractive candidates for future interventional studies aiming at HIV-1 eradication and cure. Overall design: We used Dynabeads Untouched Human CD4 T Cells kit (Invitrogen) for CD4 isolation from a median of 10 million PBMCs. RNA was extracted from CD4+ T cells using the mirVana miRNA Isolation Kit, Ambion. whole genome transcriptional profiling was performed using WG-DASL microarrays (Illumina) according to standard protocols. We included an cohort of elite controllers (n =10 ), patients long term HAART treated after the chronic phase of the infection (n=10) and patients long term HAART treated after the acute phase of the infection (n=8).

redpajama_set_name: RedPajamaCommonCrawl


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Muskoka Interval House (Bracebridge):
Chrysalis (Huntsville):
Local Phone: +1 (705) 789-8488
Contact MWAG for Further Details & Information
Is a Career in Shelter Work Right for You?
'Do you believe in working to end violence against women and children? Have you ever considered working in the violence against women field? Do you have experience or education that would be considered applicable to our work? Do you consider yourself to be well-versed in the areas of feminism, anti-racism/anti-oppression, and harm reduction?
MWAG occasionally seeks staff who are able to work on an as-needed basis. Feel free to submit your resume via fax to:
+1 (705) 645-1407 or via mail to: Muskoka Women's Advocacy Group, P.O. Box 748, Bracebridge, ON P1L 1T9.'
Muskoka Women's Advocacy Group would like to thank our volunteers for giving so generously of their time and energy to help women and children in our communities.
If you're interested in volunteering, weekly grocery shoppers are currently needed at Muskoka Interval House (MIH) in Bracebridge, as well as childcare assistants and drivers for both MIH and Chrysalis in Huntsville. Volunteer training will be provided.
If you are able to help, please contact Ruth Holloway for details:
+1 (705) 789-8488 or [email protected]
Volunteer Application Form (Insert 2022- Volunteer Application.pdf )
Muskoka Interval House
Toll-Free: +1 (800) 461-1740
Bracebridge, Ontario P1L 1T9, CA
© 2023, Muskoka Women's Advocacy Group, Shelters and Services. All Rights Reserved.


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The magical Christmas in Naples
By antonio pelliccia
Christmas in Naples in 2015 promises to be full of events and interesting initiatives and engaging thanks to the program of cultural and tourist events that will run from December 1, 2015 to January 10 in 2016.
This year's theme will be the Nativity, a concept understood both literally is metaphorical. Around this theme will turn all calendar events, to be held in several places in the city such as churches and palaces, squares and streets, and monuments.
The welcome of tourists and visitors will be entrusted to graduates of Welcome to Naples, guys who know Eastern University also 7 languages. In addition, much attention has been given to accessibility through the project Cosy Naples and the conception of dedicated routes accessible to citizens with disabilities.
The theme: Nativity
Nativity understood as birth, both as an expression of each type of creative process, both in the literal sense in reference on the occasion for childbirth. A theme that unites all the events of Christmas 2015 in Naples, interpreted subjectively by each of the artists who will be the stars of the full program, and that will be expressed in art, music, theater, archeology, science and philosophy. The Nativity has also always also inspired local crafts, as we can see in the beautiful cribs Via San Gregorio Armeno or in the works of the many artisans in our area.
Many events will refer to the concepts of peace and dialogue between peoples and own the image chosen for the campaign of the City is the Annunciation with Madonna Pregnant with Belisario Corenzio.
The places and the program
The most important location that will host the events of Christmas in Naples in 2015 will be the Royal House of the Annunciation, a historic institution for the birth and care of children where the main event will be the exhibition "Annunciazione- Nativity – Game Sacred" of Riccardo Dalisi, prepared for the inauguration of the Hall of Columns.
Other events will take place in just as important as the location of the Angevin Barons Hall, which will host a real "Festival of Birth" or "Palazzo Carafa Maddaloni with the suggestive" Ninna Nanne from the world. "
Even whole streets and squares become a stage for artists, such as the Feast of via Duomo, where the museums in the area will open in the evening with discount prices, and the road will be driven by more than 100 musicians and other artists. Also interesting is the White Night of Health with musicians, comedians and actors. In the Church of St Eligius will open the "Christmas at Saint Eligius" with lights, nativity scene and songs of popular music.
On 12 December there will be the traditional Night of Art to be held in all the historical center on peace, religion and women. There will, in the rest of the program, concert, theater, readings, exhibitions of nativity scenes and much more.
On the site of the town can be found the full program of Christmas in Naples in 2015.
Categories: Guides, Itineraries
San Domenico Maggiore
Napoli Sotterranea
Castel dell'Ovo
Metropolitana regionale
Alibus (trasferimento aeroporto)
Parthenope


It is located very close to the new Parque Corazón, in Montes de Loreto just 10 minutes from Fabrica La Aurora and 20 minutes to Centro.
Colonial style, surrounded by windows that allow natural light, 5 bedrooms – each with its bathroom – beautiful kitchen, laundry room, large terrace on the roof with views of the Parroquia and its charming interior patio – the heart of the House- with a beautiful Huizache, make this property a perfect home for large families or for those who want to invest in a small hotel B&B or rent individual rooms in Airbnb.
"Casa-hotelito Huizache" is a great opportunity for investment in San Miguel de Allende.
Recently built, the house was planned to bring best diversity and advantage to whom wanted to invest in San Miguel de Allende.


The Client Portal service menu is the list of meetings or events that you'd like to allow your clients to schedule online or for your internal use. This article will focus on creating a Group Event for your clients to schedule with you online.
Group events include you and X amount of customers, as determined by you.
To set up your service menu, select Settings>Services from the left navigation bar.
To add a new service click the Create New Service button and select Group Event from the dropdown menu.
You will then see the service configuration page.
Service Name - Set a name for your service. For example: "Weekly Webinar" or "Drop-in Yoga class"
Service Details - Add any additional information about the service so your clients will know what to expert and what the service includes. The service details will display directly below the service name on your menu.
Max attendees - The maximum number of clients that can register online to the event.
You have an option to edit this default value when you set up time for the event later on, or while editing the event.
Show on menu: Enabling this option add the event to your service menu and client will be able to schedule it themselves online.
In other cases, you may have a service that you would like to offer to certain clients, but you don't want it to be publicly available on your menu. Deselect this option if don't wish for the service to be displayed on your Client Portal service menu.
For each of your services, including those that are not displayed on your service menu, you can find the associated Scheduling Link under Online Presence> Create Direct Links.
Location - Here you will set how or where the service will take place.
For each location option, you will be able to specify an address, phone number or URL to your preferred video conference or webinar platform.
Duration - This controls the length of the service. Clients will not have the option to randomly block your schedule or choose their own meeting length.
Preparation Time - This allows you to add a certain amount of time before each service to allow for preparation. This feature is also known as "padding"; the time you set here will be added before the event starts.
Please note: The preparation time is not calculated for the first available time of the day.
Price - You may choose if you'd like to display an associated fee for a service (or not). If you decide to set a fee you may also request payment up-front for a service.
Note: in order to successfully request payment up-front, you will need to also configure your payment gateway under Settings > Payments. Click here to learn more about getting started with online payments.
Free - Don't display a fee- No fees will be mentioned when selecting this option.
Paid - Suggest to pay at booking - The fee will be displayed to your clients, and they will be asked to pay online during booking. If the client decides not to pay online, the service will still be booked but marked as "not paid" on your calendar.
Paid - Require to pay at booking - The fee will be displayed to your clients, and they will have to pay online during booking. The booking process will not be completed unless the payment is made. The payment will automatically be marked as confirmed once it is processed.
Paid - Display fee only (no upfront payment) - When selecting this option, the fee will be displayed to clients, and the booking will be completed without asking the client to make an online payment. Once the scheduling request is confirmed, you can issue an invoice for the service and offer the client to pay online, or record a payment if you collect your fees offline.
Price vary - Display as "For a fee" - If the price for your service can vary and you don't want to state a fixed fee, use this option. The service will be displayed "For a fee" when the client books it. The fees can be discussed with the client and you can issue an invoice or record the payment later on.
Staff - You may select which staff member should provide the service by default. You may change this on a per-occurrence basis.
Set occurrences: For each event you can determine the specific time which it will take place.
Before you click on Go to calendar to schedule times for the event, you should first save the updates for the service.
An event can be set with one single occurrence, or you can allow registration for this event on a daily/weekly/monthly basis.
Under Additional fields for this service you can add fields that you would like clients to complete every time they schedule a specific service.
When is this useful? You can add different fields in the scheduling request form and use them to collect information regarding the client or the client's preferences for the selected service or any additional information that will help you to provide them with a better service.
Note - The service specific fields will be displayed for both returning and new clients.
Multi Line Field - The text box displayed to the client will be bigger in order to contain the number of lines of text you will set.
Required - Check this box if the field must be filled by the clients to send the schedule request.
After you created and saved the new Group Event, the system will prompt you to continue to the Calendar to set the time the event will take place and its occurrences.
Note - Clients will be able to see the event on your Client Portal service menu if you allowed it, but available times will be offered to the client only after you have added the event to your calendar.
From the left navigation bar, select Calendar.
Repeats - An event can be opened for registration on a daily/weekly/monthly basis. You can set is to terminate on a specific date or after specific amount of occurrences.
Note - Even if you set an event to Repeat, it will not automatically add each client to each occurrence if the client is requesting the event. The client will need to sign up to each specific occurrence separately. However, the business owner/organizer may manually choose to invite a client to all events by editing a specific scheduled event set on the calendar.
Invitation only event - Upon checking this option, only clients with the unique registration link will be able to register to the event. This link will provide a sign-up for that specific time/date occurrence.
Note - Each occurrence will have its own unique link that you can share with your clients (even if the invitation only option was not checked). The link will be created after the Schedule Event setting is saved. Simply click on the specific occurrence to view the Invitation link. Click here to learn more.
Edit Event info - The event fee, attendees and type are taken from the event settings on the service menu. However, if needed, you can adjust it per occurrence.
Click on Create to save changes.
Once you have added an event to the calendar, you have an option to edit and manage each specific occurrence.
To view an event, find it on your Calendar and click on it. You will be able to see the current event settings including the number of clients that have registered, and the unique event invitation link.
Select Edit to make changes to the event. As in the Schedule Event page, you will be able to change the event date and time, communication type, fees, attendees, and mark the event as invitation only.
Making changes to an event occurrence will send an email notification to the clients in case there are already registered.
For each event occurrence, you can view how many people already registered.
If you requested a payment upfront, you can see the payment status of each attendee. You also have an option to cancel a registration of a specific attendee by selecting their name from the list on the right.
If you wish to register attendees yourself, select the Register Clients button.
You can then choose if you'd like to invite the client to the specific occurrence, or all occurrences in the event series.
You will then see the client-selection screen, which will allow you to choose multiple clients at one time.
Click Continue to add a note with your invitation, and then choose Send.
Once you make your selections and click Send, the client(s) will be automatically registered and receive the appropriate notification email.
You have two options for inviting a client to register themselves to an event (aside from displaying the option on your Client Portal Service Menu): Your Unique Invitation Link as well as the Event Action Link.
To get the Unique Invitation Link, navigate to Calendar and click on the desired event. The unique link will be listed under the event Details. This will allow the customer to register for that specific occurrence.
To get the Event Action Link, navigate to Online Presence> Create Direct Links.
Under Choose an Action section, select Schedule Appointment. You can then choose the Event from the service drop-down displayed there. This will allow the customer to choose from any occurrence that you have configured. Click here to learn more about this option.
When cancelling an event, you can select if you would like to cancel only the specific occurrence, or the whole series (which will remove all future event occurrences).
If you cancel an event, an automatic cancellation email will be sent to the clients. You have an option to type in a customized cancellation message that will be sent to the clients.


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redpajama_set_name: RedPajamaGithub


Description:'Bachelorette' Star Jean Blanc Slams Colton After 'Men Tell All' Drama: Resultado de imagem para lammar rucker . quote-a-just-society-is-not-one-built-on-fear-or-repression-or-vengeance-or-exclusion-but-john-legendjpg . to LeBron James calling himself the "King of New York" after the Cavaliers beat the.


text:
Buchtar Tabuni will be held responsible for demos calling for a referendum
April 5, 2012 News alert, syndicationbuchtar tabuni, indonesia, knpb, National Committee for West Papua, Papua, Papuan people, Referendum, right of free expression, united nations, west papuawestpapuamedia
Bintang Papua,
Jayapura: Instead of holding one demonstration as had been planned by the the KNPB (National Committee for West Papua), they held two demonstrations in two different places. One took place in Taman Imbi while the other took place in Abepura. The deputy police chief, Brig.General Waterpauw said that they would hold Buchtar Tabuni responsible for these demonstrations. 'The police will hold Buchtar Tabuni responsible for this because he was the co-ordinator of the demonstration held by the KNPB which proceeded in violation of the agreement that they would only hold one demonstration in one place, in Taman Imbi,' said Waterpauw.
He said that thousands of KNPB supporters had taken part in the demos in two places. In addition, he said, they were carrying a variety of weapons such as arrows, knives and spears, which had spread fear among the people.
Asked whether he intended to summon Tabuni, he said this was not yet clear but the matter would be attended to as quickly as possible.
The demos caused traffic jams as many main roads in the town centre were closed off.
Thousands of supporters of the KNPB held a demonstration in front of the post office in Abepura as well as near the traffic lights by the Abepura police office on Monday, 2 April. The demonstrators called for a referendum and urged the Indonesian government to recognise the Federal State of West Papua. The demonstrators also welcomed the establishment of International Parliamentarians for West Papua by Benny Wenda, a Papua who has been living for a long time in The Netherlands. The IPWP will be formally set up in a parliament to support the Papuan struggle and for West Papua to secede from the Indonesian Republic.
[The report then goes into great detail about how the demonstrations proceeded in different parts of the city.]
Speaking to the crowds, Buchtar Tabuni said: 'This demonstration is an action to express the KNPB's support for the establishment of the IPWP in The Netherlands.' He apologised to shopkeepers who had closed their shops along the roads where the demonstrations took place.
The chairman of the KNPB also explained that they were wearing traditional dress and carrying traditional weapons to show to other people (ie non-Papuans) that we have our own identity.
'Today, the West Papuan people will determine their own future which is why the KNPB has held a peaceful demonstrations with our own cultural attributes and in support of the establishment of the IPWP.' He went on to say that the Regional People's Parliament had set up commissions and said that the most effective weapon of all was the strength of the West Papuan people to confront the colonial power, the state of Indonesia.
'The Papuan people have set up their own political institutions and have asked the government of the Netherlands to place the issue onto the agenda of the United Nations.
He said that West Papua will get its freedom and this must be recognised by the international community so that we, the Papuan people, can determine our own future on the basis of one principle: it is better for us to be struck down in defending the people of West Papua than being struck down at the hands of Indonesia, the colonial power.
He said that West Papua had been incorporated into the Republic of Indonesia in a process that violated international standards, in conflict with the principles of the rule of law and international human rights. The countries responsible for this were the USA, The Netherlands and Indonesia as well as the United Nations, in pursuance of their own economic and political interests.
'This is why were firmly declare that the West Papuan people will devote all their energies to holding a referendum , to establish political institutions that conform with the wishes of the people of West Papua and we call on the Dutch government to speedily take the issue back to the United Nations.'
[The report then gave the names of 21 local Papuan organisations (PRD) the chair-persons of which had signed the statement issued by Buchtar Tabuni and said that all the leaders of the KNPB took part in demonstration.]
Meanwhile units of the police and Brimob in armoured vehicles and armed with a variety of weapons stood on guard in various points places near the DPRP office and in Taman Imbi.
Many people left their offices for home earlier than usual and discussions were taking place between members members of the DPRP.
Hundreds of people had blocked the roads causing big traffic jams .
[Abridged translation by TAPOL of a very long article that appeared in Bintang Papua.]
Thousands cram gravesite of Theys to support IPWP (westpapuamedia.info)
Thousands across Papua demand UN step up to protect Papuan people: PHOTO AND VIDEO REPORT (westpapuamedia.info)
Rallies reject Indonesian status quo in Papua, and demand referendum (westpapuamedia.info)
DPRP member: 'Journalists important for the Papuan people (westpapuamedia.info)
Military commander denies current military operations in Papua and rejects legitimacy of the IIIrd KRP (westpapuamedia.info)
← Kimanus Wenda's tumour operation	KNPB denies that violence occurred during its demonstrations →


text:
Fiduciary Focus
Partnership with LPL
Retirement Plan Tools
Worksite Financial Solutions
Hartford Office:
San Diego Office:
11545 W. Bernardo Ct, Suite 203
E-mail address: info@ethoswealthmgmt.com
Printed from: www.ethoswealthmgmt.com
Ethos Wealth Management
Hartford Office: 423 Main Street Hartford, CT 06103Phone: (860) 803-8650 San Diego Office: 11545 W. Bernardo Ct, Suite 203 San Diego, CA 92127 Phone: (858) 487-0782
| info@ethoswealthmgmt.com
What Is Your Life Expectancy?
Are you planning and preparing to enjoy a long, full life? While no one expects to live forever, you may live much longer than you think. According to the National Center for Health Statistics, a male born today can expect to live to age 76 and a female to age 81. 1
1) Source: National Vital Statistics Report, Vol. 66, No. 6, 2017 (data as of 2015)
Considering that 65-year-old retirees could spend as much as one-third of their lives in retirement, the need for sound lifetime financial management becomes evident. Remember that these figures are based on averages — so you are just as likely to live longer than the average expectancy as you are to die sooner than expected. Are you financially prepared for a long, full life?
Your gender: 0
Your current age: 0
Your life expectancy is age: (This figure is just an average. Make plans for a long life.) 0
Did you know that the older you are, the longer you are likely to live? It seems illogical, but it's true. The chart below shows the current life expectancy of males and females at various ages.
Securities offered through LPL Financial, Member FINRA/SIPC. Investment advice offered through Good Life Advisors, LLC, a Registered Investment Advisor. Ethos Wealth Management and Good Life Advisors, LLC are separate entities from LPL Financial.


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People, Culture, & Leadership: What Makes Embark Different
Clancy Fossum. December 13, 2018 . company culture
The term different is a catch-all with gradients and nuance, equally applicable to everything from unicorns to mustachioed hipsters, but not in the same sort of way. Embark falls on that gradient scale of different, a notion we don't try to hide. In fact, it's something that we revel in, a distinguishing source of pride that's as reliable as the ocean's tides or traffic on a downtown freeway.
You see, Embark has no intention of joining the sea of uniformity in the financial space. When your founder and CEO isn't an accountant and lets a genuinely entrepreneurial spirit carve his path, the resulting firm is bound to be, well, different. For Embark, that has made all the difference in the world, from the top of our organizational food chain down to the newest of new hires.
Of course, that's just a component of what makes us unique, a single ingredient to the secret sauce that separates us from the rest of the industry. Give us a few minutes and we'll give you another sampling of our special blend of managerial herbs and spices with the hopes that you'll walk away with something beneficial for your own enterprise. Do we think we know everything and have this thing completely wired? Nope, we will always be a work in progress, just as every company with an eye towards growth should be. But we've certainly picked up a few things in our short corporate lifespan thus far that make this place special. Want a small hint before we dive in? It's all about your people.
Talent Is Everything
Embark has engineered nearly every aspect of our firm around talent which, at first glance, seems like an obvious decision that everyone should make. In reality, however, other companies might say they always put their people first but, when push comes to shove, the people are usually the first "cost centers" that firms prune like a rose bush in spring.
Emphasizing talent starts at the top and trickles down through policies and procedures, actions and culture that make it clear to all where an organization's priorities fall. Sure, recruiting talent is instrumental as well, but a steady inflow of even the most innovative minds does a firm no good if the culture is toxic and creates nothing more than a revolving door of talent. And counteracting that corrosive dynamic, our financial friends, doesn't always lend itself to a robust P&L.
Embark invests in its people, even though it hurts our short-term bottom line. Just like any type of investment, we're always playing the long game. Through benefits, education, technology, a highly-curated culture, and a non-stop pursuit of the ideal work/lifestyle balance, we're building a phenomenal place to work, where every employee is a crucial building block to a stable and prosperous future. That's money well-spent by anyone's standards.
People Want to be Challenged
The best talent doesn't want to sit on their laurels. They want to excel and never stop growing in their knowledge base and skill set. Those are the people that Embark seeks out, the ones that are both talented and motivated to succeed, that never stop reaching for something bigger and better. In fact, our management team must often implement policies to properly throttle that drive, ensuring that it coincides with a healthy and fulfilling life outside of the office. Embark doesn't want a supernova that illuminates the entire night's sky but quickly runs out of fuel and goes dark. Instead, we want the steady stars that are the best at what they do, are consistent, and capable of shining bright for the long haul. Those are the team members that an enterprise builds an outstanding, enduring culture with.
We continually challenge our team members, both within their individual positions as well as their role in the enterprise. Part of that process is connecting them to the why? part of the equation, seeing how their singular puzzle piece works in conjunction with the others to complete the corporate puzzle, taking daily incremental steps to improve themselves along the way.
Development evolves in lockstep with a challenging environment. As we challenge our people, they inevitably continue to develop as they strive for personal and organizational goals. Embark also takes careful consideration to design positions that are inherently challenging, making certain that our talent will never stop pushing themselves to improve. That's where the investment in our team really shows up, as our people begin to build on ever-increasing knowledge and create a snowball effect that Embark, its employees, our partners, and clients all benefit from. Without that devotion to a challenging environment, the very same snowball effect could have a reverse impact, as seen in so many firms with overwhelming turnover and the accompanying costs involved.
Organizations are like wooden ships built for a life at sea, traversing often contentious seas to get to their desired port before they regroup, stock up on supplies, and head back out. Every plank of those wooden ships must fit in seamlessly with one another or everyone onboard is in peril. Embark takes this analogy to heart when choosing who will join our team.
Our culture is too deliberate, efforts too meticulous to risk a faulty plank or two from threatening the seaworthiness of the enterprise. To that end, our recruiting begins with two personality tests to see if the prospect is a good fit for Embark, how they need to be developed, and who they would work well with on our team.
Ultimately, its the fit within our culture that reigns supreme, far surpassing intelligence, skill, or even experience. Once we find those unique individuals, we hold on to them for dear life, challenging and help to develop them as we go to build something great, something lasting. The way we see it, an enterprise built of the right people that invests in those team members will build a stronger brand, delight the clients, and continue building on itself. That's the Embark way, obviously a little different than the average firm but, in all honesty, we wouldn't have it any other way. We're doing something great over here and being different is the wind in our sails.
Tagged: company culture
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FACT: Everybody makes typos. The writers at WhiteSmoke make typos. Language experts and journalists make typos. The Queen of England, if she uses a computer (or even a typewriter), probably makes typos.
The term typo is an abbreviation for typographical error. We like the definition provided by Dictionary.com : "An error while inputting text via keyboard, made despite the fact that the user knows exactly what to type in."
However, some typos include contextual spelling errors, which spell-checkers (such as Microsoft Word) simply do not catch, since they are words spelled correctly, but used incorrectly. WhiteSmoke's spell checker can correct contextual spelling errors, too.
An article titled "When is a typo like a veto? When it thwarts a vote" was published in the June 25, 2009 issue of The Daily Sentinel, a Texan newspaper.
The article described America's voter registration process, and how typos can have potentially devastating effects on one of our country's basic foundations as a democracy.
When a voter registers in his/her county, identification information is recorded (i.e. first/last name, driver's license and/or passport information, date of birth) and entered into county databases, resulting in the issuance of voter registration cards. These cards enable voters access to polls on election day, and are crucial components of the voter process, for record-keeping purposes. Typos committed by the clerks who enter voter registration forms (i.e. entering a person's driver's license, birth date, last name or passport number incorrectly) result in discrepancies between the voter's actual identification information, and what appears on his/her registration card. This means when a voter appears on Election Day to vote, he/she is not permitted a vote, because the voter registration card was not properly processed, resulting in the denial of an American citizen's right to vote.
Just like we all mess up certain parts of our speech - if we're preoccupied, nervous, distracted - we all occasionally mess up parts of our writing.
Check your work. When you have finished a paper or even an e-mail, read over it carefully.


text:
Gotham's Jada Pinkett Smith doesn't think Fish Mooney will return for Season 2
Krystal Clark
Tag: Gotham
Tag: Jada Pinkett Smith
Early in its freshman run, Fox renewed Gotham for a second season. The show has spent a considerable amount of time introducing multiple villains, with some taken directly from the Batman canon while others were created from scratch. Fish Mooney is a character who was made specifically for Gotham, and her journey has been filled with ups and downs.
But despite Fish's resilience, she may be living on borrowed time. In an appearance on Live With Kelly & Michael, the actor behind the character, Jada Pinkett Smith, didn't seem hopeful about Fish's future. When asked about her return for next season, the actress said, "I don't think so, I signed for a year and the year's up."
Co-host Michael Strahan replied, "I'm holding out hope because, you never know, Fish Mooney could show up anywhere." Pinkett Smith agreed, "Yeah, she could show up anywhere. You never know!" After that somber moment, the actress stressed that the first season isn't over, and there are still "great things" to come.
Fish Mooney has probably been the show's most polarizing figure. Pinkett Smith plays her in a way that's very theatrical and larger than life. But then again, should we expect anything less? This is a woman who gouged her own eye out to prove a point. As a whole, Gotham has greatly improved with the second part of the season. But it may be suffering from villain overload.
What do you think? Should Fish stay, or should she go?
(via The Wrap)


text:
Iustînivka (în ) este o comună în raionul Pidhaiți, regiunea Ternopil, Ucraina, formată numai din satul de reședință.

Demografie

Conform recensământului din 2001, majoritatea populației comunei Iustînivka era vorbitoare de ucraineană (%), existând în minoritate și vorbitori de alte limbi.

Note

Iustînivka, Pidhaiți, Ternopil
Iustînivka, Pidhaiți, Ternopil
Iustînivka, Pidhaiți, Ternopil

redpajama_set_name: RedPajamaWikipedia


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Home Hemp Cannabis Connection Vermont Legislature Passes Legalization Bills, Legalizes Retail Sales
Vermont Legislature Passes Legalization Bills, Legalizes Retail Sales
by Jean-Gabriel Fernandez
In a long-awaited move, the Vermont Legislature agreed to fully legalize marijuana, becoming the second state to do so through legislation after Illinois. The personal possession (up to one ounce) and cultivation of marijuana were legalized in Vermont in 2018, but retail sales were still illegal. The state Legislature remedied that by finally agreeing on S. 54, a bill that will finalize the legalization process in Vermont.
"I am really pleased that after having introduced some of the first cannabis legalization bills over 20 years ago, we are finally achieving a tax and regulate system with some of the strictest controls on corporate ownership and added protections and resources for youth prevention," said Vermont's Lieutenant-Governor David Zuckerman. "This comprehensive and forward-thinking bill addresses the historical harms of the war on drugs, which disproportionately affects communities of color, including here in Vermont."
At the same time as S. 54 passed the Vermont Senate, its sister bill, S. 234, was approved as well. "That bill will automatically expunge the criminal records of over 10,000 people convicted of possessing two ounces or less of marijuana. The bill also decriminalizes possession of between one and two ounces of marijuana," Zuckerman explained.
This is a resounding victory that comes at the end of a long, winding road to legalization. S. 54, which legalizes the sale and regulation of legal, adult-use marijuana, has been a year in the making. Both the state House and Senate agreed to it independently, with major differences, forcing the bill to be reviewed in a bicameral conference committee to reconcile the two versions. Ultimately, lawmakers agreed on several key points of contention.
Tax Revenue
The final version of the bill includes an excise tax on cannabis products equal to 14% of the retail price in addition to the state's 6% sales tax, which is higher than the Senate's original 10% tax proposal. One-third of the revenue from the excise tax would be used to fund drug-prevention and resources. The bill also contains social justice language to support cannabis ventures from Vermont citizens who were disproportionately impacted by the war on drugs, and it includes the creation of a new, independent Cannabis Control Board that will oversee the budding cannabis market. Each municipality will have the power to grant or withhold permits, giving local governments the power to prohibit cannabis retail stores.
The official timeline provided by Vermont's Legislature indicates that the act is supposed to take effect by Thursday, Oct. 1, but the real change will occur when members of the Cannabis Control Board, who will be tasked with delivering cannabis licenses, start working, between January and February 2021. The recently revealed fiscal analysis of the project shows that the Vermont Legislative Joint Fiscal Office estimates that marijuana sales will bring at least $650,000 in additional revenue every year, plus local fees that municipalities will be allowed to collect. They estimate that Vermont will obtain between $13.3 and $24.2 million in cannabis revenue by fiscal year 2025, including licensing fees and the regular state sales tax.
The bill is now in the hands of Republican governor Phil Scott. Gov. Scott has been the source of much worry for Vermont's cannabis activists, in particular due to his insistence to include provisions to address potential impaired driving once marijuana is fully legalized. The final version of the bill does address the issue, but it takes a more liberal approach to it than Gov. Scott called for: In order to conduct a THC (the psychoactive substance of cannabis) test to determine if a driver is indeed high, police would need a search warrant, and the test cannot be taken on the side of the road, except for a breath sample, which is a step down from what Gov. Scott announced as his condition to sign the bill.
As a result, Gov. Scott has said that he will "take a look" at the legislation before deciding whether to sign it, allow it to become law without his signature or veto it. "We'll take a look, we'll reflect on all of the areas of disagreement, then I'll make a decision from there," he said.
As it stands, both houses of the state Legislature have agreed with a large, bipartisan majority on the two legalization bills that are now sitting on the governor's desk. Moreover, a recent PBS poll found that only 24% of Vermonters oppose the legalization, taxation and regulation of marijuana sales, while 68% outwardly support it.
To read more Cannabis Connection articles, click here.
To read more articles by Jean-Gabriel Fernandez, click here.
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Here you will find out fifteen games like Starbound. Starbound features action-adventure gameplay where you go through several sandbox things like crafting, gathering, exploring, and the main one as surviving. The game takes place in a 2D mode where you visit several places and perform activities of collecting things that you can use to fight and building towns and villages.
Starbound Gameplay takes you in the massive space where you are lost, and now you aim to survive in any way. The adventure gets on as you start visiting the space and strange things within. There are monsters to kill, NPCs to take quests and much more.
Check out our collections 2018 Best action-adventure video games like starbound for Android, Xbox, PS4 and on Steam.
The game deserves to be on the list as it brings a great amount of action and adventure. In the game, you get involved in several exciting tasks like crafting those giant robots and take part in fights against those monsters. The quest system keeps it all interesting where robotic clarion helps you in that virtual world.
Gameplay takes place in several environments as you explore and collect things to make useful things. Here you experience the ability to create while getting in several battles with the opponents. This way, the game world brings you endless exciting things and completing missions get you upgrades.
Again a role-playing game that presents the data in 2D environments. Here the main ingredient is the survival mode that makes players try it from all over the world. Other than survival, it also makes you manage your resources, collect things, craft some equipment and explore the worlds.
Gameplay starts once you choose your character and class and it offers abilities accordingly that you use later for collecting and building purposes. Players will face several types of monsters as their enemies that you need to kick out of your way. Also, you can make purchases for the resources you want.
The next one is the Crashlands as one of the Starbound alternatives. The game offers the same survival mode that can also feel like Don't Starve. The game sets you in the space environment where you need to stay alive fighting against all the odds. The harsh environment makes you explore, collect resources, and develop things using them.
Gameplay focuses on getting back to your planet, but it's not that easy. You have to improve your stats, fight enemies, build your ship and explore a lot. Inventory management is also necessary as new tools come to be used, so you continue your adventure.
This one also features the sandbox genre where the player is dropped on a random world to explore and stay alive even in the harsh states. Exploration is the main objective as you will find several hidden treasures and resources. To keep it interesting, there are several obstructions and monsters are one of them.
Gameplay includes collecting items so you can survive there like collecting food, weapons, decorating items, and much more. Weaponry can be upgraded once you explore and collect weapons that you can use in battles and win the opponents. That soundtrack always runs in the background matching the situations.
The game directly takes the sandbox technology that set you in the space to give the same fun gameplay like Spore. Here you create your spaceships, shields and other tools that save you against odds. You are al.one on a planet, and there are a few resources, so you start collecting them and build up things of your need.
You also explore other world and asteroids once you are able to take your ship out. You collect all the minerals and elements that make your journey easy and let you survive in that environment. Customisation options are always available so you can fill your ships with several abilities, and in StarMade it's always fun to pay.
The game brings you a unique experience of sandbox genre that mixes up several similar games, and that's why it undoubtedly comes as one of the Starbound alternatives. Here you become the manager of the dwarf society that you manage and make it grow. You make explorations to find what is necessary for your community and save it from the monsters.
Gameplay includes searching for the resources, collect them and make items that you can use to go forward on your adventure. Here quests take you to several types of monsters that you fight against and collect your reward after winning over them.
Another one that comes up with the action-adventure genre and sandbox elements but in the 2D environment. It offers role-playing other than exploring a lot of places and finding resources. It all feels like a creative game where the player can choose the difficulty level and a permanent death mode is there too.
In the gameplay, you take up several quests and go on battles in the 2D adventure game. The multiplayer environment is worth playing where you enjoy it all with your friends. So, Terraria is not any less than all these games here and the one that you must try.
This amazing game brings you experience that action-adventure genre where you explore the beautiful world. The colourful vibes wit vibrant creatures are the attraction point of the game that includes sandbox like content. Taking survival as the main point, it lets you visiting all strange places and finds your hope there.
As you go ahead and uncover things, you surely get rewards as being a lawyer who has lost his spaceship. Gameplay takes you on the journey of mining resources and uses them to build up your spacecraft. Also, there are combats if you want some action RPG and trading is available too.
The next one among the Starbound like games is this game that mixes up several genres. The game world provides you with a purpose where you aim to save the world and restore it to the best situation.
Gameplay remains side-scrolling in the 2D mode where you are free to roam or explore just after setting up your character. Here you get new things as you complete missions and learn things like spells, get resources, save people, build things. The more you level up, the more capable you become to take down the evil power and this way you go along with the storyline.
The second version of 'A Valley Without Wind' where you take the role of the hero forward to save the world. The new version unlocks more places and powers that can be used against the demons.
Gameplay is identical with some advanced aspects such as you make strategies and experience turn-based combats. Exploration and action are two main concepts here where you rescue the world, develop buildings and survive. Here are twelve classes available to choose from that come with different abilities, and you can experience the entire game world by switching them as you want.
The game includes Action-Adventure with the survivor genre and features a Single-player mode. The world has all destroyed due to an unknown virus, and now you are one of the few survivors. You aim to survive in harsh situations and slash everything that comes in your way. The open world makes you feel free to move just anywhere.
Gameplay offers you a first-person perspective where all you can see is that hand holding the weapon. Here you lay traps to save your base at night and visit NPCs to take help about the game. In the night mode, it's nothing special other than the dark.
Minecraft: Story Mode is the legendary one among in the sandbox genre that he established as the most addictive game of the century. It has action, adventure, crafting, mining, building, exploring, and much more. Here as being a protagonist, you access the beautiful world of Minecraft and complete missions as assigned.
If you're looking to add some new life to your Minecrafting, you should check out our fifteen best Minecraft mods.
Gameplay is point-and-click where you make convo to different NPCs and take their help. Other than exploring and mining, puzzle solving can be felt too. Combats and other action based events are there, so you don't miss battles, and it all makes it here among the Starbound like games.
What can be better than all these fifteen games like Starbound? These games offer all that a Starbound alternative should have and if you think the same then go ahead with any of these and enjoy the action-adventure genre with various other elements.


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UK House Price Index
This June, an all new UK House Price Index will be launched by the Office for National Statistics, replacing the existing indices currently published by the ONS itself, and the Land Registry for England and Wales.
The new Index will merge these two HPIs, and incorporate additional data from Scotland and Northern Ireland as well as the Council of Mortgage Lenders. Based on completion prices, it will give a UK-wide picture, and be updated monthly.
By bringing all these datasets together, and by employing the best internationally agreed methodology, the Government believes the new UK HPI will give the most accurate and detailed picture of the UK housing market yet.
What this means for your portfolio
At the moment, we update all our properties based on a RICS Chartered Surveyors valuation every 3 months. This will remain the case.
In the months between these quarterly independent external valuations, we adjust every property's value in line with the existing Land Registry House Price Index. Updated property valuations are published on the 5th of the month, or the first working day thereafter.
The ONS has informed us that the publication of its new UK House Price Index will be delayed until 14 June, which means we won't be able to revalue our properties on Monday 6 June as usual.
However, the quarterly RICS desktop valuations are unaffected by these changes. Throughout June, RICS accredited surveyors will be carrying out revaluations of all our properties. This data will be used to update all valuations on 5 July, synchronising our whole property portfolio into a new, consistent quarter-end valuation cycle.
From 5 July, this simple new rule applies. Once each and every property has reached fully funded status and legal completion as a New Listing, they will immediately be listed on the Resale market at their RICS value, rather than, as now, at their purchase price.
Please note that once the new UK House Price Index has been released, we will also need time to analyse its data and methodology. While we're doing this, we won't be providing monthly revaluations between the quarterly updates.
The case for commuter belt property


text:
package org.ggp.base.util.concurrency;

public class ConcurrencyUtils {
	/**
	 * If the thread has been interrupted, throws an InterruptedException.
	 */
	public static void checkForInterruption() throws InterruptedException {
		if (Thread.currentThread().isInterrupted())
			throw new InterruptedException();
	}
}


A triplex pump is a type of constructive displacement pump utilized in a number of high-stress applications. Good displacement pumps operate on the principle of progressively reducing the volume of the working fluid and forcing it into a discharge opening, thereby increasing stress, which benefits in delivering a flow. This pump is a reciprocating pump that utilizes 3 plungers or pistons to pump the functioning fluid, therefore the name triplex pump. Pistons are generally utilized in triplex pumps that are appropriate for systems with operating pressure of up to 1000 psi, whereas plungers are usually employed when the operating pressure exceed 1000 psi.
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Palm Springs, California-based attorney Kevin Cortright is offering aggressive advocacy on behalf of his clients seeking workers compensation claims. He is confident that he is the best option for clients looking for active help, and that he will obtain the best medical care for clients while fighting for every dollar they deserve. Mr. Cortright and his team have additional expertise in claims dealing with bankruptcy, auto and truck accidents, pedestrian accidents, bicycle accidents, and dog bites.
Each year, thousands of people in California get hurt on the job and seek medical help and attention. A workers compensation insurance policy makes sure that an employee has medical help, as well as wage replacement for not being able to work. One must notify his or her employer immediately after an injury. While the process seems pretty straightforward, a representative for Kevin Cortright says that is not always the case. "We see it all the time ... our clients are not getting the full coverage of help that they deserve. You really need someone that knows all the ins and outs of workers compensation to get you everything you are entitled to."
Mr. Cortright and his team also want to be clear for their clients on what work-related injuries encompass. As the website explains, "It's not just injuries that happen in your workplace. It also includes injuries and illnesses that happen on job-sites, during work-related motor vehicle accidents, after exposure from a workplace accident, or health problems caused by repeated movements at work. These injuries may occur at one time, or develop over a period of time." The representative also says that, "People don't know maybe until years later the severity of their condition due to work-related injuries."
"There are potential hurdles for obtaining the needed help by Mr. Cortright's clients," says the representative. It is possible that an employer might attempt to stop an employee from filing a claim, or try to fight it. As Mr. Cortright states, "You may ... be dealing with an angry employer or an employer who is trying to prevent you from reporting the incident that caused your injury. It can be confusing and hard to know what the right thing to do is at any point in the process." Kevin Cortright has more than 15 years of experience in the workers compensation field. "You need experience," says the representative. "And you need someone who is going to fight for you and what is best for you. Kevin Cortright is a top Palms Springs Workers Compensation Attorney for a reason."
The first step that Mr. Cortright's office says one should take when injured on the job is to seek medical help immediately. "Don't listen if your employer is begging you not to, or asks you not to mention that your reason for needing medical attention is work-related," the representative says. The representative also states that it's possible that an employer will threaten with termination to stop an injured employee from reporting the incident, but that this is not legal in California. "Go get help," says the representative. "No one has the right to stop you from getting the medical attention that you need."
The second step that Mr. Cortright's office says one should take when injured on the job is to seek out an experienced workers compensation attorney. One client says, "I was injured on the job. My employer said I wasn't entitled to compensation. I didn't know what to do, so I went online. I found a few attorneys ... but none of them really seemed to understand my unique situation. Then I discovered Mr. Cortright and it's like a light went off."
The Law Offices of Kevin Cortright's website lists multiple cases in which they have gotten their clients thousands of dollars through settlement. "Kevin Cortright is a Palm Springs Workers Compensation Attorney that you can trust," says the representative. "With as much experience he has, and the care he demonstrates for his clients, there really isn't another option to consider." The practice is confident in their aggressive advocacy approach for their clients, that they will achieve favorable results.
Kevin Cortright offers services in additional to workers compensation claims such as personal injury accidents, dog bites, and bankruptcy claims. His clients seem to be receptive to what he is doing - Mr. Cortright's practice currently holds a 4.8 Google rating. One reviewer states, "Cortright Law was professional and actively involved with my case. I would go to them again for legal assistance."


Our factory purchase grains raw material from farmers directly so that reduce the product cost without intermediaries.
HPS, Machine Clean or Color Sorter. According to Customer's request. Strictly Quality Control system .
3. What's the minimum order?
One full 20 feet container.
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FAST Shipment within 10 to 15 days.
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Yes. We can supply free samples.
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