text:
2013 News Feature: As genomics breaches cancer walls, researchers forge new treatment paths
As genomics breaches cancer walls, researchers forge new treatment paths
By Steven Benowitz
Associate Director of Communications, Extramural Research Program
More than ever before, researchers are poised to reach across cancer treatment boundaries and are developing new plans of attack against a wide variety of diseases.
In May, The New York Times hinted at this, reporting on two new studies that detail the genomic landscapes of endometrial cancer and a type of leukemia called acute myeloid leukemia (AML). The Times - acknowledging that the findings showed dramatic similarities among endometrial, ovarian and breast cancers - suggested this was the "most telling evidence yet that cancer will increasingly be seen as a disease defined primarily by its genetic fingerprint rather than just by the organ where it originated."
The two studies mentioned are part of The Cancer Genome Atlas (TCGA), a multimillion dollar effort begun in 2008 to unravel the genomic aberrations behind many types of cancer. TCGA is a collaboration jointly supported and managed by the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI), both parts of the National Institutes of Health (NIH).
As TCGA research papers were published on individual cancers - glioblastoma, breast, ovarian and others - and genomic data started to accumulate, investigators began noticing similarities across cancers, patterns in the chaos. Every "marker paper" had its share of surprises, such as novel gene mutations and new cancer subtypes. But, all too often and as expected, researchers repeatedly encountered the same alphabet soup of misbehaving genes and pathways - TP53, RAS/RTK, and HER2, to name a few - that primarily sabotaged control of cell division, growth and development.
Rather than silo each cancer by organ site, as had been done historically, scientists are now finding a new way to pool all of this information and see commonalities among disease types. This theme - similarities among cancers - is central to a project called the Pan-Cancer initiative.
Pan-Cancer was launched in 2012 as a next logical step in TCGA studies. In September, the Pan-Cancer project, armed with TCGA genomic data from more than 5,000 tumor samples in 12 cancer types, was announced to the world in publications in several journals.
The first round of Pan-Cancer papers included two research papers in Nature Genetics that showed, among other things, that a limited number of genetic alterations are responsible for most cancer subtypes, and that mutations most often occur in certain regions in the genome. In the newest Pan-Cancer study, researchers surveyed nearly 5,000 tumors from 21 different cancer types, uncovering more than 30 new cancer genes. Their results - reported online on January 5 in Nature - indicate that many more cancer genes have yet to be identified, meaning additional tumor samples and cancer types need to be analyzed to develop a comprehensive cancer gene catalog. Such a catalog may ultimately help shape personal treatment approaches.
While TCGA marker papers continue to uncover more potential drug targets for individual cancers, the Pan-Cancer reports are increasingly creating topographic maps across cancers, with biological mountains and valleys, charting the roads that therapies might take. Such maps have the potential to change the way researchers and clinicians understand and attack cancer. As researchers point a finger at the guilty cancer genes, proteins and pathways, they also hope to understand their behavior and learn how to control the cancer process. Rather than attacking individual genes or protein targets, they hope to launch a global assault from different vantage points.
"The Pan-Cancer project is showing us for the first time what is different and what is shared among cancers, and is helping us put everything into a common picture," said Charles Perou, Ph.D., the May Goldman Shaw Distinguished Professor of Molecular Oncology, and professor of genetics, and pathology and laboratory medicine at the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill. "That is fundamental information that is laying the groundwork for future research and treatment strategies."
For example, he said, scientists and clinicians have "hinted at similarities among basal-like subtype breast tumors, and ovarian and lung squamous cancers for years, but now we can say that genomic changes - changes in the gene p53, the number of gene copies and expression signatures - are all being seen together and uniquely in these three groups."
Most of the "clearly druggable targets" are known, said Dr. Perou, who is a breast cancer specialist. "Now, we are in the next phase of examining other, more indirect targets in pathways, and entire chromosome regions instead of only single genes. Pan-Cancer studies are helping us place these newer kinds of targets in the context of the larger cancer picture."
New approaches to treatments, clinical trials
Scientists and clinicians hope that Pan-Cancer studies will ultimately help provide insights for new treatment approaches, though the approaches will be multifaceted, rather than a one-size-fits-all approach to cancer therapy.
"Despite the many crossing patterns we are seeing, if you look at 100 patients with the same type of cancer, you'll find many similarities and differences. There are many roads to cancer," said Richard Wilson, Ph.D., director of the Genome Institute at Washington University in St. Louis.
Genomic profiling of tumors is already becoming routine oncology practice, particularly in some larger centers. Patients can have their tumors profiled for a range of known mutations and alterations, and certain therapies can be ruled out, and others tried.
Dr. Perou said that TCGA Pan-Cancer studies and other genomic analyses of tumors might mean new classifications - and in some cases, changes in cancer diagnoses and therapies - for perhaps as many as 15 percent of cancer patients. Clinical trials could be reformulated according to these newer classifications.
In some cases, clinical trials have already begun to change, according to Douglas Levine, M.D., a gynecologic oncologist at Memorial Sloan-Kettering Cancer Center (MSKCC) in New York. Dr. Levine helped lead the TCGA projects on ovarian and endometrial cancers. At some larger institutions, for example, enrollment in early stage clinical trials is less based on the kidney, lung, colon or other organ site that is affected by cancer, and more on the specific genomic abnormalities seen in the tumor.
At MSKCC and elsewhere, one new approach is the "basket" trial. Rather than treating subtypes of disease only by site of origin, such trials test the effectiveness of a drug on a specific molecular abnormality seen in many different cancers. In a trial, patients with different types of cancer can be grouped into similar or separate baskets.
"In a basket trial, we would profile a patient's tumor and the patient would end up in a HER2, BRAF, EGFR or some other mutation basket," Dr. Levine said. While HER2 gene amplifications - meaning there are extra copies of the HER2 gene in cells - help drive 25 percent of all breast cancers, mutations in the HER2 gene are also found in a small number of breast cancers. However, the same alterations are also found in some bladder, lung and gastric cancers.
Such similarities are not guaranteed to make a difference in patient care. Clinicians and clinical studies have to show that the same drugs or cocktails of drugs have a similar impact on patients who carry the same key genomic alterations in different cancers. Drugs that are effective against melanomas that carry a mutation in the BRAF gene, for example, don't work well in colon cancers that harbor the same mutations.
"Pan-Cancer has highlighted pathways common to many cancers, and continuing studies will offer a way to dissect those pathways and help provide clues why one tumor responds to a drug but others do not," Dr. Levine said. "To help our patients, we want to find out who is responding and why."
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As the time approaches for our move to France, (we are hoping for autumn 2015, but it could be sooner or even longer, we shall wait and see), I thought it was time to assess what furniture we need to take with us. One look around the bedroom changed everything because it was very apparent that restoration and renovation was in order.
My husband had made our linen chest when we were just a few years into our married life. Forty years later the linen chest was crying out for help. I could not part with the chest, so restoration was in order.
I do aspire to French Country manoir colours (really rural country), so the paint we picked for the chest was Craig and Rose 1829 Regency white which fits the time period of our French property.
First was the hard task of removing the old red leather covering from the lid of the chest. The chest was a dark rusty brown colour in need of serious sanding down quite a few times. I had broken nails to prove it.
Next step was to buy the foam padding and material for the lid. An Internet search did find a few gorgeous selections of material, but they were all very expensive. I particularly liked a few on e-bay, vintage Lora Ashley was very tempting. Then I tried a local shop that reupholsters furniture, to see if they had any remnants of material in blue. Luckily they had and it was free, great. So after several coats of paint, the lid was covered and what a transformation, I had caught the restoration bug.
The left over fabric was the ideal size to renovate a bedroom chair, the colour of the finished chest and chair do not match anything in our bedroom in the UK but they do match the colours of the bedroom in France.
Restoration was dependent on the British weather so I am afraid to say that the furniture was in and out more times than I care to remember.
Restoration was dependent on the British weather I am afraid to say.
Here is the finished chair, complete with its cushion alongside the newly restored linen chest.
Adam is now open for business!
He is a 3D freelance artist-so check out his site www.thevicker.com, it is awesome. He intends to continue on his freelance work after we have all moved to France towards the end of next year.
We are going to France for our "working" holiday next month; a lot to do in the downstairs of the property however, one of our jobs will be to measure each room so that Adam can create 3D images in order to envision the furnished rooms.
The very expensive but gorgeous confectioner Laduree which was founded in 1862 has released its mouth-watering Easter collection for 2014. Among the gorgeous things that you can buy is the cloche or bell range. Cloches volantes are a traditional Easter confection in France, symbolising the legend of the bells flying to Rome on Good Friday. From this date no bells are heard until Easter Sunday, when they return to herald Christ's resurrection.
Ladurees Cloche Lapin is a dark or milk chocolate bell, filled with chocolate bonbons, delicious. The Cloche de Paques is a dessert available for six to eight people from April 17-21, consisting of chocolate macaroon biscuit, bergamot orange cream, orange and bergamot jam, chocolate mousse and crispy praline slivers. My mouth is watering already.
If you are going to France for Easter do check out the local confectionaries for hand crafted eggs, bells, rabbits etc. The displays alone are truly wonderful to see.
Unfortunately all of my family are on a diet so no Easter chocolate for us, except I will be making an Easter cake which will be covered in chocolate. "Just a small piece of cake please".


text:
Tabanus bishoppi is een vliegensoort uit de familie van de dazen (Tabanidae). De wetenschappelijke naam van de soort is voor het eerst geldig gepubliceerd in 1933 door Stone.

Dazen

redpajama_set_name: RedPajamaWikipedia


Welcome to our Archives page. On this page you will find totaly 53 of our articles broken down into Months and Years.
"I've already overcome so much. From not being capable of anything to now tackling trips to the grocery store, baking in my kitchen, sitting at my computer to write, and playing my instruments. Whenev	read more..
I just keep thinking, What can I do to make myself better? My current success comes from a positive attitude, a great team of doctors, my support system, and the services I've received from the N...	read more..
"A program that has really helped me is the Peer Support Group in Portsmouth. I've met so many inspiring people and I find myself always saying; "If she can do it, so can I." Today, I'm 33 and marrie	read more..
"I guess after all these years I feel like I've finally come home. So much has changed for me since moving to New Hampshire 10 years ago, but one thing that hasn't changed is the New Hampshire As	read more..
"All my life I've been independent. I know that I can't let my vision loss get me down. I have to keep living my life. Thanks to the training and support I've received from my many friends at the New read more..
"I have always been a high achiever, and I would like to stay that way." Linda Piekarski has never been in the United States Marines, but that famous slogan of theirs has really inspired her. In fact...	read more..
"I love the life I have right now" When I was only fifteen, I was diagnosed with Type 1 Diabetes. At the time, I didn't know what diabetes was all about or how dangerous it really was. The doctors ta...	read more..
Volunteers make a world of difference in the lives of over 1000 clients, who live throughout all counties in the state. The inability to drive is the most significant limiting aspect for a person with...	read more..
Thank you for your interest in supporting Future In Sight. It doesn't matter how large or small your contribution is, it will go a long way in helping your family members, friends, and neighbors remai...	read more..
"I can't imagine what it would be like to be blind or severely visually impaired." "It is a great joy to me, knowing that the work of the Agency will continue long after my volunteer days." – Persis G	read more..
The New Hampshire Association for the Blind provides specialized programs and services for approximately 2,000 individuals annually. From school-aged children to working-age adults, to senior citizens...	read more..
You can pay tribute to a loved one or memorialize a friend or family member by making a gift to Future In Sight. Your donation can be made online by using a credit card or by calling the Development D...	read more..
Thanks for Caring. Future In Sight provides specialized programs and services for approximately 2,000 individuals annually. The Association relies on private support to help meet its mission to ...	read more..
Future In Sight assists people who are partially sighted so that they can use their remaining vision more effectively. Low vision evaluations and training in the use of low vision aids and devices is ...	read more..
Professional instructors from Future In Sight provide the skills necessary for clients with a visual impairment to travel safely and with confidence in almost any environment. Points to remember: ...	read more..
Rehabilitation instructors teach the skills that are necessary to live safe, productive lives by using and making the best of their remaining vision. Working one-on-one with our clients, the foc...	read more..
NH Association for the Blind provides vital education services to children from birth to age 21 who are blind or visually impaired, including those with multiple disabilities. Our itinerant Teachers o...	read more..
The hallmark of the NH Association for the Blind's rehabilitation program is the one-on-one training we provide. We go where you go, at home, at school or at work, wherever help is needed the most! Ev...	read more..
The Association is an official national partner for the USABA/Wellpoint Foundation National Fitness Challenge. The program will run through November 30, 2014. The goal of the program is to raise the p...	read more..
Nate Abbott – Gilmanton Iron Works Maureen Kelliher – Dover Sheila Zakre, Esq. - Concord read more..
August 14, 2013 The New Hampshire Association for the Blind has been awarded full accreditation by the National Accreditation Council for Blind and Low Vision Services (NAC), following a six-month ag...	read more..
September 1, 2013 The primary purpose of the position will be to develop and strengthen relationships with local organizations/agencies in an effort to promote the education and awareness of vision l...	read more..
10th Annual 3K Walk for Sight a HUGE Success!
We surpassed our goal – Raising over $75,000 for this year's 3K Walk for Sight! We would like to express our sincere thanks to our walkers, donors and friends for their continuous support of our missi...	read more..
June 2013 The Reader's Digest Partners for Sight Foundation recently awarded a $25,000 grant to the New Hampshire Association for the Blind. These funds will be used to offset program expenses fo...	read more..
The New Hampshire Association for the Blind received a $2,000 grant from the Bishop's Charitable Assistance Fund to support its Vision Rehabilitation Therapy Program. This program helps restore the in...	read more..
November 20, 2014 At the recent annual meeting of the New Hampshire Association for the Blind's Board of Directors the following individuals were elected to serve as officers for the 2015 Fiscal...	read more..
To continue its 100th anniversary celebration, the Association went back to its roots on a Sunday in September. Emma Coolidge Weston, a resident of Hancock, NH, is credited with founding what would be...	read more..
April 2015 - Concord, NH - George Theriault, President and CEO of the New Hampshire Association for the Blind, has announced his plans to retire at the end of 2015. The work of the Associati...	read more..
June 2015 - What would you do, if you were blind for a day? That's what some of the 6th grade students on Team 4 experienced at Cooperative Middle School in Stratham on Wednesday, June 3, 2015.&...	read more..


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Home Reviews Irregular Recruits review – "Not just another roguelike deckbuilder"
Irregular Recruits review – "Not just another roguelike deckbuilder"
Smelly wildfolk, tentacled leeches and literal scaredy cats – Irregular Recruits lives up to its name in that you'll recruit all kinds of wayward creatures into your army in order to explore the Cinder Lands. The roguelike card game is supposedly a combination of Slay The Spire elements plus auto-chess-esque features, but does it hold its own against the multitude of similar titles in the same genre?
THE STORY OF IRREGULAR RECRUITS
As with other roguelike card battlers, Irregular Recruits' narrative is based entirely on the encounters you stumble upon along the way. Lady Luck plays a big part here, as is the nature of randomly generated encounters. You can stumble upon anything from special upgraded weapons lying on the ground to a man-eating dragon where you'll have to sacrifice one of your recruits for safe passage.
The beginning of the tale will depend on which commander you pick. There are eight of them to choose from with two initially unlocked for you to try out. I've unlocked five out of the eight so far, and I can honestly say that each one brings not only its own set of unique cards and strategies but also a different gameplay experience altogether.
IRREGULAR RECRUITS GAMEPLAY AND VISUAL
The jaw-dropping artwork in each card alone should already set this game apart, to be honest. While the game might seem like your run-of-the-mill roguelike card battler at first glance, it actually offers an entirely different experience as you go deeper into the title. I was pleasantly surprised at the fresh content it brought to the table, as it opts instead to take the best elements of card battlers and add its own twist – and to think this was all done by a solo indie dev.
In particular, you can't choose which enemy card to attack in Irregular Recruits – the game does that for you. This initially left a sour taste in my mouth, because how can you strategize your battle plan if you can't pick which enemy to take down first? Of course, as I went deeper into the game, I realized just how much strategizing you still have to do to ensure victory in every round.
For instance, your commander gains experience points you can spend on skills, and these alone add a layer of depth to your plan of attack. Apart from the cards you recruit into your army, you'll also have to choose which boon you want to take after each battle – do you prioritize getting new cards, or do you bring back to life a card that died in battle? Because permadeath is very much a thing here, when a member of your army dies, it's gone forever – and when all of your troops are lost, you die. Your army is essentially your HP.
Playing the game feels challenging, frustrating and exhilarating at the same time, as all great roguelikes should. The sound effects never feel overbearing, and are just enough to get you going during particularly adrenaline-pumping matches. I also absolutely adored the background music, which perfectly fits the fantasy world you're thrust into from the very beginning of the game.
I did try the auto-battle function here, and surprisingly, the AI actually does a pretty good job at helping you breeze through matches (sometimes even better than myself, I have to admit). It's not hard to invest hours of your time into the game only to look up and realize that so much of your day has already passed. With so many titles in the same genre, it's hard for me to find something that actually makes me feel like it's worth my time – and Irregular Recruits definitely does that really, really well.
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redpajama_set_name: RedPajamaCommonCrawl


We sailed away from the safe harbor of Panajachel, Guatemala to get to the other side of the lake on this Christmas morning. Locals pay 15 Quetzales for the ride, but touts wanted 30Q's for tourists. We refused to pay more than 25Q and that amount was quickly accepted.
Lake Atitlan is known to be the most beautiful lake in the world. Whether or not that is true, it certainly is a lake of great beauty. Twelve miles long and 7.5 miles wide, locals crisscross the lake several times a day from various villages. We are headed to Santiago, the largest of the lakeside communities for our Christmas Day Pig Roast.
Years past when Billy was first here in the 1970's, there was only the mail boat that cruised the lake with any regularity. Twice a week this boat delivered mail to the towns dotted along the lake. You simply caught a ride on the mail boat, and if you got off at any location, you had to spend the nights there awaiting the next boat's arrival. Today there are many boats coming and going to all the towns several times a day.
Christmas Eve is a big event in Guatemala and this year did not disappoint. Large fireworks set off in the streets at midnight kept everyone up into the early morning hours. From our hotel floor-to-ceiling windows we watched the fireworks explode and rise to the sky from below. It was a tad close!
Almost 2 million years ago there was a huge volcanic eruption which formed the caldera now filled by the lake. This enormous eruption dispersed ash over 3.7 million miles and has been detected from Florida to Ecuador.
The depth of the lake is disputed, but is considered to be more than 1,000 feet deep.
On February 4, 1976, an earthquake of 7.5 magnitude struck Guatemala and killed more than 26,000 people. This earthquake fractured the lake bed causing subsurface drainage from this body of water, and the water level dropped two meters within one month! Now, that fracture has been closed due to other earthquakes which have taken place since then and the lake is rising once again.
The pig is in the pit!
We arrived to our host's home and after some fresh tropical fruit and coffee, it was time to take the pig out of the pit. Last evening, Christopher and Kevin placed it into the earthen oven with glowing hot coals. It's been cooking all night.
Now it was time to remove the pig and see if the overnight cooking did its job.
Christopher gets in on the action too.
It was a tremendous amount of work the night before with killing the pig, allowing it to hang for hours, stuffing the inside with fruit and onions, then wrapping it up in banana leaves, wet burlap bags and chicken wire. The head-sized volcanic rocks inside the pit had to be heated to bright red before the pig was lowered into it.
What would we find this morning?
A little he-man power and the pig in all his wrappings is lifted from the hot oven and placed on stone slabs.
The general consensus was that the pig was not hot enough. Was it cooked all the way through? The boys shove a knife blade into the center of the pig to test the internal temperature.
After all this work and time, no one wants to believe it is not cooked through and through even though everyone thinks the temperature should be hotter at this point in the cooking cycle. So Mr. Piggie needs to be unwrapped to have a closer look.
First the chain ties were cut, then the chicken wire peeled back. The burlap bags were next and then the banana leaves. What would the pig look like?
Mr. Piggie is not completely cooked and must be returned to the flame. What are we going to do now? About 30 people are expected for Christmas dinner and the main course isn't finished just yet!
It's hard to feel too troubled when living in paradise. The weather was a mild 78 degrees with clear skies and a gorgeous ancient lake in front of us just beyond the lush gardens.
Oh gee. What shall we do about the pig?!
It is decided that the pig will be finished off on a grill and Christopher just happens to be living next to a famous restaurant and is friends with the owner. How convenient is that? So the guys take the animal, table and all, down the hill and right next door to place him on the grill. The pig is very heavy and it takes four guys to move him.
Some heave-ho-ing and the pig and table are brought into the downstairs garden cooking area of the restaurant. An amazing 5 foot long grill complete with firewood and a lid is all prepared with a fire roaring below. Shouldn't be too long now. Amazingly, we are still pretty much on schedule - so far.
The pig is laid on a grill with drainage pans underneath that are filled with water to create steam and prevent a grease fire. He's a perfect fit, the lid is closed and now we just wait for the guests to arrive.
The pig is moving along and getting the proper heat now, and we check the water pans to be sure they have enough water.
Here we see a family using their boat to attend a Christmas function farther down the lake. It's a beautifully tranquil day.
The pig is looking good now and and our host decides he is ready enough to eat.
A bit of a taste test while the men gather around to see what the next step might be. Everyone is loving being a part of this big project!
With a knife, Zaira starts carving porky. Pieces are placed into a cooking pot with a lid and are portioned out to the guests.
It's been a great day with the women bringing down the plates and utensils, making guacamole and washing dishes. The guys have set up the tables and chairs, filled the tubs with ice for the refreshments and carried porky back and forth several times. Everyone has worked up an appetite and the surroundings are idyllic.
Everyone is hungry, Zaira is doing a great job of carving and Christopher is passing out plates. Billy is ready!
The guys didn't waste any time. Pork slabs, black beans, guacamole, tortillas, chips, cake. It just couldn't be better! Fresh poinsettias and tropical flowers dress the table.
Porky has sacrificed his life and we are all grateful. There was solid teamwork and the day was gorgeous. Mixed conversations in Tz'utujil, Spanish, and English are flowing between everyone and there are plenty of smiles and heartfelt warmth to go around.
Our hosts were the best. Such open-heartedness and generosity! The day passed all too quickly and because we stayed well beyond the last water taxi, a private launch was called to pick us up at the neighbors dock.
We bounced along the dark waters for almost an hour as the sun set and the new moon rose. Stars were brilliant above us in the sky and it was the perfect ending to an exciting and fulfilling day.
One not to be forgotten.


text:
Q: Proper usage of std::atomic, pre increment value as function param I have code where I need unique id (packet id for some protocol). So I used std::atomic<int>. After reading documentation I was confused because it stated that increment is done in this way. fetch_add(1)+1
I understand that value inside fetch_add is incremented atomically but I get pre-increment value +1 outside atomic operation. What I would guess is not atomic.
Can I use some_func(++atomic_value)?
I wrote simple code to check if it works. And it works but I don't understand why.
#include<iostream>
#include <atomic>
#include <thread>
#include <vector>
#include <random>
#include <mutex>
#include <algorithm>

std::atomic<int> Index = 0;
//int Index = 0; // non atomic Index. It will generate duplicities

std::vector<int> Numbers;
std::mutex Mutex;
std::default_random_engine Generator;
std::uniform_int_distribution<int> Distribution(5, 10);

void func(int Value)
{
    std::lock_guard<std::mutex> Guard(Mutex);
    Numbers.push_back(Value);
}

void ThreadProc()
{
    Sleep(Distribution(Generator));
    func(++Index); // is this proper usage of std::atomic?
}

int main()
{
    const int ThreadCount = 1000;
    std::vector<std::thread> Threads;

    for ( int i = 0; i < ThreadCount; i++ )
    {
        Threads.push_back(std::thread(ThreadProc));
    }

    for_each(Threads.begin(), Threads.end(), [](std::thread& t) { t.join(); });

    std::sort(Numbers.begin(), Numbers.end());
    auto End = std::unique(Numbers.begin(), Numbers.end());

    if ( Numbers.end() == End )
    {
        std::cout << "No duplicites found." << std::endl;
    }
    else
    {
        std::cout << "Duplicites found ! - " << Numbers.end() - End << std::endl;
        for_each(End, Numbers.end(), [](int n) { std::cout << n << ", "; });
    }

    return 0;
}

Off-topic question: When I defined Index as non atomic I get duplicities but only from end of range. Numbers are always 900+. Why it is so?

redpajama_set_name: RedPajamaStackExchange


text:
CS:GO October 12, 2019 / 12:00 am
OpTic Gaming CS:GO Team Disbands; Players Seeking Offers
Cody Luongo
OpTic Gaming's Counter-Strike team has officially disbanded in full, with its players seeking offers to play elsewhere.
OpTic Gaming's CS:GO team is officially disbanded. (Image via OpTiC Gaming)
The American organization has failed to maintain any type of consistently good form in the last year, culminating in a poor performance in the ESL Pro League Season 10 group stage, which the group would finish last in. This result forced the self-benching of team captain and in-game leader Mathias "MSL" Lauridsen, who expressed his feelings in a tweet, saying: "I have decided to bench myself. When I joined [OpTic], the plan was to build a strong team and buy out strong players, but because of [OpTic] getting sold, that changed and we have constantly been in a position where we couldn't build a proper team."
While OpTic Gaming remains one of the most iconic and recognized organizations in all of esports, its purchase by Immortals Gaming Club in June of this year had steered the team in a strange direction. With Immortals Gaming Club ownership in both OpTic and MIBR running contrary to Valve's conflict of interest rules, the company was forced to release one or the other. Since then, Immortals had stated during the time of acquisition they would relieve the OpTic Gaming CS:GO team and were supposedly in search of a proper home.
From MSL's statement, it seems operations were a bit muddled within the team in regards to finding and maintaining a proper roster, which Kristian "k0nfig" Wienecke echoed on Twitter, saying: "We have chosen to disband the OpTic lineup because there is no future in OpTic." K0nfig said. "I strongly feel like this is the best choice."
There is certainly a good deal of talent within the pool of players now made available for purchase out of their contracts with OpTic – it'll be interesting to see who gets picked up and where.
The following OpTic members are open to offers:
Nikolaj "niko" Kristensen
Kristian "k0nfig" Wienecke
Rene "TeSeS" Madsen
Mathias "MSL" Lauridsen
Casper "ruggah" Due (coach)
An American journalist specializing in business, gambling and Counter-Strike - Cody was a competitive gamer first before starting his career in esports. Competing in several titles including Halo, Counter-Strike and Rainbow Six prior to his career as a journalist where he would go on to write for ESPN, Esports Insider, SickOdds and many more.
CS:GO Zakaria Almughrabi Jan 8 2023
CS:GO Zakaria Almughrabi Dec 18 2022


text:
Mt. Barker, the main street [B 3581] • Photograph
[General description] Gawler Street, Mount Barker, looking west up the hill towards Auchendarroch, the summer residence of the Barr Smith family. Township buildings line the street in which cars are parked. The car in the centre of the road was one of three registered to the Murray Aunger Motor Company in February 1918. A Dodge Tourer, parked on the right near the Savings Bank, was registered to J.G.H. Paech of Callington in June 1924. [On back of photograph] 'Reproduced in the Chronicle, Mar. 27, 1926 / Main street, Mt. Barker'.
This image has no known copyright restrictions.
Please refer to the State Library's Conditions of use
Photograph; 30.3 cm x 18.3 cm
Approximately 1926
Part of Mount Barker Collection
Mount Barker (S.A.)


Fix an issue where the OLAP drill through action causes Excel to stop working. Fix an issue where Excel hangs when trying to edit a workbook that contains numerous text boxes. Fix an issue, caused by a recent security update, where opening an HTML file from an untrusted location opens Excel with a blank (empty) screen with no errors displayed, instead of allowing the user to open the file in... 15/11/2017 · I am getting the dreaded "Microsoft Office Excel is waiting for another application to complete an OLE action. I have checked and tried various MACRO's but nothing is working I have done a search within this forum and still nothing.
15/11/2017 · I am getting the dreaded "Microsoft Office Excel is waiting for another application to complete an OLE action. I have checked and tried various MACRO's but nothing is working I have done a search within this forum and still nothing.
1/06/2012 · Suppress "Microsoft Office Excel is waiting for another application to complete an OLE action." Become a Registered Member (free) to remove the ads that appear in thread area. Click here to reset your password.
This step-by-step guide will help you to install Office 2016 Group Policy templates in Windows 10 Pro or Enterprise editions.
19/04/2011 · after a rather long time (1mn 30s, during which Excel is frozen) I get a message box saying "Microsoft Excel Is Waiting For Another Application To Complete An Ole Action."


We stock a growing range of high quality wall stickers. What sets our products apart from some other sellers is that we only use high quality vinyl and a professional cutting process.
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Further Comments: A driver spotted a tall male figure, wearing a leather jacket, with medium length black hair standing on the roadside. The witness said that the figure literally appeared out of nowhere and vanished soon after being seen.
Further Comments: While cycling home a witness braked hard to let a small dog cross in front of him - the puppy moved half a metre out of the way before vanishing on the grass verge.
Further Comments: A black dog the size of a donkey, this entity was said to let loose the most unearthly cries.
Further Comments: The area round the well found at this inn is home to a ghostly hunchback.
Further Comments: The nickname given to an Australian worker on the base who blew himself up trying to sabotage a Lancaster bomber during World War Two was maybe a bit too unkind, and he was seen for years after his death walking around on the perimeter road. A ghostly NCO also made a comeback at the former base. Sergeant Sinclair was in charge of loading bombs onto the aircraft here during the Second World War; a mistake caused a bomber to explode on take off, killing Sinclair while he was trying to flag the aircraft down to alert them to the error. For a short while his ghost was seen on the runway, arms waving wildly in the air.
Further Comments: As this creature followed a woman, she turned and lashed out with her umbrella - only for it to pass straight through the creature.
Further Comments: The castle was haunted by a phantom hare. Locals believed the creature to be a ghostly witch who was once held in the castle. The entity was said to leap over people or run between their legs, and any dog sent after it would return crying out.
Further Comments: A large aircraft moved silently over the tree tops, so low that the witness thought it would land or crash into a field. It was later identified by the witness as an Avro Lancaster.
Date / Time: Still present!
Further Comments: The winds which whip and whistle around the Stump are said to be caused by the Devil. He was once cornered by St Botolph; the saint preached so intensely, the only thing the Devil could do was huff and puff, and the gasps have not yet subsided.
Further Comments: Several ghosts are said to haunt this site, including a phantom woman who peers into the former jail cells, people being hanged, and the sound of snoring.
Further Comments: Two members of a wedding party returning to their room were met outside their door by a man in white overalls. He told them he was working in the room next door for the 'next twenty minutes, but would try to keep the noise to a minimum'. Retiring, the guests heard the man next door sawing and hammering for an hour. The following morning the guests complained about the worker to the manager, who told them there were no workmen on site. A few minutes later a female employee at the hotel approached the guests, having overheard the conversation, and told them that the room was haunted by the ghost of a carpenter who had died during the 1970s. The employee also said she had once seen a ghostly woman in a blue dress in the bar.
Further Comments: Approaching the theatre from the west end of Spain Lane, this witness noticed a short (5 foot - 5 foot 3 inch) hooded figure in a full length cloak at the opposite end of the building. As the witness neared the figure, it turned, revealing the expressionless face of a young fair haired woman. Within a couple of seconds the figure vanished into thin air.
Further Comments: A local legend says this area of road is haunted by a woman who died there during the 1970s or 1980s. One driver, returning home with three friends in the car, spotted her in the road and swerved to avoid the figure. Looking back, she had vanished, and while all in the car said they had seen her, one said that she seemed to vanish as they approached where she had stood.
Further Comments: The phantom grey lady who haunts this site is said to likely be Catherine Digby, a popular local lady who died in August 1811.
Further Comments: Buried at the nearby church, this knight materialises at the hall (by a portrait) and rides a spectral mare to the graveyard to ensure his body hasn't been disturbed. He also sometimes appears in the church itself.


text:
"Navajo Nation Police Need 775 New Officers"
"With less than 200 officers on the Navajo Nation Police force, getting to this large amount is a lofty goal, especially when it comes to the budget."Arlyssa Becenti Navajo Times, June 11, 2021
Navajo Police Chief Philip Francisco walks down a roll of newly recruited police officers at the Navajo Police Training Academy on Jan. 2 in Chinle, Arizona.(Photo by Sharon Chischilly/Navajo Times)
Excerpt: Navajo police need 775 new officers, report says...Arlyssa Becenti Navajo Times, June 11, 2021
"The Navajo Nation Police needs 775 officers to meet community demands across the Navajo Nation, according to an assessment done by Strategy Matter and Navajo public safety leadership…'The demands on this department are extreme,' said Liz O' Connor, consultant team lead. 'The range of issues officers are called upon to address, the vast distances they must cross, and the limitation of radio and cellular coverage as well create a nearly impossible situation every day for so many officers in a department of this size.'
The Navajo Police Department's assessment is 174 pages long and took 18 months to develop. The assessment was unveiled to the public in late May. With this assessment three basic questions are answered such as: Where are we now? Where we want to go? And how will we get there?
But the number of officers needed was the big takeaway from the report…'It's a unique report for the Navajo Police Department,' said Chief Phillip Francisco. 'It's a lot to digest…some of the recommendations is we are extremely short staffed. Seven hundred fifty would be the ideal number of officers to really do the job that our community demands and to keep our officers safe,' he said. 'We have a long way to go to get to that point.'
When it comes to the demands placed on the Navajo Nation Police, Navajo lawmakers are quick to express needed service from officers without investing in them. The biggest example is absolutely nothing is done to acquire safe buildings for officers and personnel in Window Rock and Shiprock.
Even more obvious is delegates continuing to advocate for outside police forces to come onto Navajo Nation to help police the Navajo people, an option that Francisco doesn't agree with…Other weaknesses include: the sense of department unity is not consistently present; information flow is a real challenge for technical and organizational reasons; facilities, the Window Rock station is in a serious state of disrepair, and the Shiprock station is closed; general orders and rules and regulations are outdated (1979) and unhelpful; COVID-19 impacts: it is harder than ever to connect with residents; there is significantly increased demand on dwindling resources at NPD and for partners; recruitment challenges: money, interest, training, disqualifications, available housing, and perceptions among youth.
But the strengths identified include: commitment and dedication of officers at all ranks; younger generation of NPD staff see the department as a unified whole; greatly improved—and growing—confidence in department leadership, among officers, civilian staff, partners and others; thorough (top to mid-managers) commitment to officer wellness and improving early intervention programs; partners and potential partners recognize the challenging circumstances of law enforcement on the Nation and want to support efforts to improve operations, safety, and coordination.
For this, the Strategy Matters and public safety leadership consulting team suggested that NPD set an initial target of 500 personnel, with 300 serving as patrol officers, and 200 serving as command and support personnel. These numbers are based on a budget-driven authorized-level approach the Nation has been using and the workload-based approach. 'We learned the NPD leadership is visionary, highly accountable, and trusted by officers, residents, and staff alike,' said O'Connor. "Invest in this department."
Celebrating Gay Pride Month!
Lesbians in Ballet: 'Has Anyone Like Me Ever Walked These Halls?' By Siobhan Burke, The New York Times, June 1, 2021
Two Juliets- Audrey Malek, left, and Cortney Taylor Key, rehearsing a duet with the choreographer Adriana Pierce. Credit- Yael Malka for The New York Times
"Ballet's strict gender norms put pressure on women to conform. But dancers who don't are finding they're not alone." S. Burke, The New York Times, June 1, 2021
Category: Culture, Law, Native Politics | Tags: Navajo Police


text:
Recording the story of music at Malvern Winter Gardens, Worcestershire, UK
This website celebrates the story of popular music performances at Malvern Winter Gardens from 1961 to 1990. It is a unique catalogue of memorabilia and a record of memories from those who attended the gigs. Find out more about us or get in touch.
Search the gigs:
Featured memories
Audience member Hilary Postle recalls the special atmosphere of the Lindisfarne gig on 24th October 1974
Sharon Paley remembers with pride seeing Ozzy Osbourne at Malvern Winter Gardens, October 1980
View all memories
The Falcons, Johnny De Little, 15 June 1963
As a member of the original Falcons (formed in 1958) we played the Malvern Winter Gardens a number of times at the famous Saturday Night Dances, alongside the Eric Benson Dance Band and the Dennis Wheeler band.
Packed audiences in the ballroom, loads of people in the Pump Room and last but not least queues for drinks in the bar.
The Winter Gardens in Malvern was a unique venue for top artists but also for local talent. The organisation always supported this and the dancegoers, the fans & the followers never let us down. The attendances were invarioubly as high as for the professionals.
Saw many top artists (hundreds) during this great and unforgettable period. The memories will never be erased …….. Dave Edwards
By Dave Edwards (11/12/2019)
The early 1960s: teen idols come to Malvern
I was there as well. Adam Faith was at the top of the hit parade in December, 1961.
I spent 3 months helping out at the Winter Gardens before joining the RAF in Jan 1962. As it was a sit-down concert we set out 100s of chairs in the ballroom. Every place was taken and it was a great performance.
Tyrannosaurus Rex, The John Dummer Blues Band, The Spirit of John Morgan, Rebellion, 28 September 1968
At this T-Rex show my now husband of 48 years was bass player in the support band Rebellion. The line up consisted of Stewart Halion (bass), Rob Mason (drums), Phil Goddard (guitar) and John 'Spike' Nolan (vocals).
By Lynne Halion (03/11/2019)
More new comments


Hi all)) My name is Nadya and I'm from Russia, from the city Voronezh. I am fond of the anime from 2010, and of cosplay from 2011. I sew all my costumes (exсept little parts) by myself. Wigs are also styled on my own.
For the blue color the arms and legs are fabric body-suit separate from the dress, on the face is the aqua make-up Snazaroo.


text:
Apple Watch exec takes over secretive car project
September 9, 2021 In Uncategorized By Sean OKane
Just two days after Ford hired away Doug Field, the head of Apple's secretive car project, the tech giant has tapped Apple Watch exec and former Adobe CTO Kevin Lynch to take his place, according to Bloomberg.
It's the latest changing of the guard for the project, known as Project Titan, which has rotated leaders about as much as it has reportedly shifted focus. To wit, Korea's Maeil Economic Dailyreported earlier Thursday that Apple may no longer be trying to work with other automakers to bring its autonomous electric car to life. Rather, the report states, Apple now plans to go it alone.
Lynch started working on the project in July, when he was brought on to help develop the vehicle's software. He joined Apple in 2013 from Adobe,…


Offering you a complete choice of services which include pile load test service, pull out test services and pile integrity testing services.
We are reckoned as the flagship firm that is affianced in providing Pile Load Test Service. This testing service is rendered by our team of adroit professionals to evaluate pile capacity, driving stresses and hammer performance during the installation of piles. In order to provide maximum efficiency, reliable results and promptness, this testing service is executed with the help of the best in class testing and sophisticated technology. Besides, our esteemed clients can avail this testing service from us at reasonable price.
Pull Out Test Services is in response to a growing industry requirement to increase the safety and security of fixings and anchors widely used in most construction materials. There has been a major increase in the use of pull-out testing, particularly with local authorities who demand that a specific pull out testing programme should be carried out on site by the contractor which is then endorsed by recorded evidence. It is therefore essential that all such site personnel should be thoroughly familiar with the use and understanding of pull out testing equipment. In this respect our operatives have been extensively and robustly trained and are fully certified in pull out test in concrete, which are recognised by local authorities and others in the industry.


text:
About Max Dana
MD Art
Design / Furnitures
MD Characters
World of Sama
Max Von Sama
Mr. da-eYe + da-eYe Jr.
MD Commitments
Kids Workshop
Finest Craftsmanship
MD Websites
MagkaSama Project
Sama Gazette
da-eYe.com
MD Info
Twitter: @MaxDana
MD Blog
🐦 @MaxDana
"60 Signers for the 60th Anniversary" Initiative
For the 60th Anniversary of the Universal Declaration of Human Rights
An artist and a philanthropist, and founder of the MagkaSama Project, Max Dana has always been a staunch supporter of Human Rights, and she wanted to mark the 60th Anniversary of the Universal Declaration of Human Rights in 2008. To do so she launched the "60 Signers for the 60th Anniversary" Initiative to support the Every Human Has Rights Campaign (The Elders / CIVICUS).
For several months, Max met with sixty people from the most important organizations in the world (Amnesty International, UNICEF, UNHCR, Human Rights Watch, FIDH, UNESCO...), to volunteers and individuals supporting organizations, as well as committed people (doctors, lawyers...). She also met with the 30 winners of the Internews Every Human Has Rights Media Awards. They all enthusiastically supported Max's initiative and signed the original artwork she created to honor the Universal Declaration of Human Rights.
Geneviève Garrigos, President of Amnesty International France and partner of the Every Human Has Rights campaign declared: 'By marking human rights on every inch of the globe she drew, even on the most remote places in the world, Max Dana enforces the universality of the Declaration of Human Rights on its 60th anniversary.'
Katy Cronin, Communications Director, The Elders added: 'I am very grateful to Max Dana for her creative and inspiring support for The Elders and the Every Human Has Rights campaign. This artwork is a wonderful reminder that any committed individual can take action to change the world for the better. Thank you Max! And don't stop now!'
Jean-François Julliard, Secretary general, Reporters without Borders - RWB/RSF said: 'It is a great initiative and an orignal and creative way to raise awareness on human rights. The universality of Human Rights shouldn't restrain to signers on a map, all the people who signed this art piece should now act and defend Human Rights the best they can.'
Sama Kids Day
Kids Workshop with Max Dana
Sama Kids Day (also known as Kids Workshop) is a special Sama Day. Max Dana enjoys sharing her art with kids, and she runs her own kids workshops.
She brings children and the arts together since 2006. Children are naturally creative, and Max encourages them to explore creativity through various art forms (painting, music, photography, art & craft…).
Each workshop focuses on an event or on a specific topic, with activities covering a wide range of subjects allowing the children to express themselves freely, sharing and enjoying time together.
An inspiring moment to create global awareness, to build empathy and global citizenry through arts education and discussion.
Craftsmanship & Métiers d'Art
Craftsmanship and Savoir-faire
When it comes to create a unique piece of jewellery, to select the finest fabrics for her clothing line and interior furnitures, and materials for her pieces of design combining brass, marble, leather, glass and porcelain, or to make her large-scale bronze sculptures, Max Dana is always looking for savoir-faire craftsmanship.
Artistry and Attention to detail
Max favors working with teams comprised of world-class craftsmen and craftswomen, using time-honored methods and simple tools to create elaborated pieces crafted by hand. Meticulous attention to detail, expertise and skill of master craftsmen are essential components of Max's creations.
Combining craftsmanship and innovative technology is also important to Max to design beautiful products and create unique works of art using 3D printing, smart textiles, LED lighting, or nanotech materials.
Copyright ©1994-2021 Max Dana. All rights reserved.


The Association of American Railroads is offering an up-close view of technology as seen through a railroad lens.
The AAR and six Class I carriers on May 15 will present RailXTech, giving Congress, federal regulators, and members of the media a hands-on look at rail technology that is helping the industry meet the challenges of tomorrow. The event is designed to show freight rail's technology investments are making railroads safer, more environmentally friendly and more efficient.
These cutting-edge technologies will be brought to life through a virtual reality experience, locomotive and track inspection simulators, hands-on demonstrations and one-on-one conversations with leading technology experts from America's freight railroads.
Of the AAR members railroads, BNSF will show automated track inspection with a focus on autonomous inspection cars and drones, and hands-on inspection cameras and a drone equipped with a special inspection camera.
Canadian Pacific will display smart sensor technology for rolling stock with a focus on wheel safety featuring a full-size wheel.
CN Railway features bridge, steel structure and rail inspections featuring hands-on testing of steel rail components.
CSX plans a focus on the technology behind locomotive engineer training, and information about the AskRail app for emergency responders featuring a locomotive virtual reality simulator and demonstration of the AskRail app.
Norfolk Southern demonstrates big data analytics with a focus on track monitoring and replacement featuring a welding training virtual reality experience and ultrasonic track inspection tools.
Union Pacific shows rail car and track inspections with a focus on machine visioning featuring a flash LiDAR camera for 3D photos and a Xenics camera for thermal images.
The event takes place from 10 a.m.-4 p.m. in the Rayburn Foyer, 45 Independence Ave. SW, Washington, D.C. Register at https://www.aar.org/railtech.


Optimize transition care management with naviHealth.
Transition care management (TCM) has become a critical priority for healthcare organizations nationwide. By more effectively and cost-efficiently managing patient transitions from acute to post-acute care, healthcare organizations are able to significantly improve patient outcomes, avoid readmissions, enhance patient satisfaction, and lower the overall cost of providing health care.
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naviHealth has been a pioneer in transition care management for nearly two decades, offering a combination of scalable technology, clinical services and advisory solutions. For health systems and health plans navigating the shift from fee-for-service to value-based care, naviHealth offers post-acute-care expertise, proprietary technologies, clinical support and a post-acute provider network. With naviHealth support, organizations can optimize their quality, clinical and financial outcomes in transition care management.
Clinical support services, including the ability to embed naviHealth clinicians at hospitals and post-acute facilities. Our experts work side-by-side with your transitional care teams to guide patients to the right post-acute setting, minimizing the risk of avoidable readmissions and reducing unnecessary care.
Advisory solutions that leverage nearly two decades of transition of care management experience and expertise to improve enterprise-wide operational efficiencies, develop key insights and benchmark provider performance.
Scalable technologies that reduce the amount of time spent on labor-intensive transition care management tasks by automating and standardizing processes and workflows.
Advantages of naviHealth services for transition care management.
Interact with patients more effectively throughout their journey and receive daily heat maps that provide alerts to potential patient problems.
Develop key operational performance metrics to identify high-performing providers.
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Reduce readmissions by referring patients to the right post-acute setting.
Use automated decision-making tools to give clinicians more timefocusing on the patient.
Streamline workflows, optimize efficiencies and enhance network relationships with top providers.
Learn more about transition care management with naviHealth.


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text:
Q: Upgrade Typeorm version 0.2.28 to 0.2.45 I want to upgrade my typeorm version from 0.2.28 to 0.2.45 but when I tried to start the server I had an error that said:
C:\Users\user\Documents\project\server\src\connection\ConnectionOptionsReader.ts:154
        connectionOptions.forEach(options => {
                          ^
TypeError: Cannot add property baseDirectory, object is not extensible
    at C:\Users\user\Documents\project\server\src\connection\ConnectionOptionsReader.ts:155:34
    at Array.forEach (<anonymous>)
    at ConnectionOptionsReader.normalizeConnectionOptions (C:\Users\user\Documents\project\server\src\connection\ConnectionOptionsReader.ts:154:27)
    at ConnectionOptionsReader.<anonymous> (C:\Users\user\Documents\project\server\src\connection\ConnectionOptionsReader.ts:141:25)
    at step (C:\Users\user\Documents\project\server\node_modules\tslib\tslib.js:144:27)
    at Object.next (C:\Users\user\Documents\project\server\node_modules\tslib\tslib.js:125:57)
    at fulfilled (C:\Users\user\Documents\project\server\node_modules\tslib\tslib.js:115:62)

any hint ? I don't know where is the problem
Edit: I found that the problem comes from version 0.2.42 , in the changelog there is a breaking changes
update listeners and subscriber no longer triggered by soft-remove and recover
Do you guys have an idea to how to fix it ?

A: I found that the problem was in createConnection, it was like that:
createConnection().then(async () => {
  console.log(`Server is running at http://localhost:${PORT} `);
});

and i just added the ormconfig as argument in createConnection:
createConnection({
    "type": "postgres",
    "schema": "",
    "host": "",
    "username": "",
    "password": "",
    "database": "test",
    "port": 5300,
    "synchronize": true,
    "logging": true,
    "entities": ["src/**/*.entity.ts"],
    "migrations": ["src/migration/**/*.ts"],
    "subscribers": ["src/**/subscriber/**/*.ts"],
    "cli": {
      "entitiesDir": "src/entity",
      "migrationsDir": "src/migration",
      "subscribersDir": "src/subscriber"
    }
  }).then(async () => {
  console.log(`Server is running at http://localhost:${PORT} `);
});


The apartment is in the center of La Mata and just steps from the beach. It is located on the first floor on the east side. The living area consists of 2 bedrooms, 1 bathroom, kitchen and sun terrace. The apartment is fully furnished and equipped. Nearby are pharmacy, supermarket, restaurants, bus stop, cafes, bars.
Apartment maintenance costs: IBI 230 euro / year, rent 450 euro / year.


As Founder and CEO of FarmaTrust, Raja is driving the company's vision and mission of protecting the vulnerable by eliminating deadly counterfeit medications on a global scale.
By using Blockchain technology based on Ethereum, FarmaTrust is creating a transparent, auditable, secure, global system to track genuine pharmaceutical products, providing confidence to patients and medical practitioners worldwide.
Raja has significant international management experience, having worked in USA, Asia as well as the Middle East. He is a UK qualified barrister with over 20 years business experience.


Melanie Margalis reacts after winning the women's 200-yard individual medley final at the 2016 AT&T Winter National Championships at McAuley Aquatic Center on Dec. 1, 2016 in Atlanta.
Team USA's women dominated the final evening of the 2017 Arena Pro Series event Saturday at the Indiana University Natatorium in Indianapolis, racking up five wins and nine total podium spots. The men weren't to be left out, earning five more top-three performances themselves, giving Team USA a grand total of 29 podium finishes over the three-day meet.
2016 Olympian Hali Flickinger got the evening off to a strong start, earning her second win of the 2017 Arena Pro Swim Series in the 200-meter butterfly with a 2:09.49 to lead a Team USA sweep. Continuing her rebound from a meniscus injury suffered playing flag football, Cassidy Bayer was 0.67 seconds behind in 2:10.16. Hannah Saiz, a 2013 NCAA champion for Kenyon College, rounded out the all-American podium at 2:11.32.
Olympian Molly Hannis continued the women's winning ways in the 100-meter breaststroke, staging a comeback over the last 50 meters to overtake Olympic bronze medalist Katie Meili for the win in 1:06.47. Meili was 0.53 seconds back, while Iceland's Hrafnhildur Luthersdottir was third in 1:07.94.
Ali DeLoof kept the wins coming for the U.S. women by taking the 100 backstroke in 59.82, 0.47 seconds ahead of Great Britain's Jessica Fullalove and 0.96 up on Italy's Federica Pellegrini, the 200-meter freestyle Olympic champion in Beijing.
Melanie Margalis, a member of the winning 4x200-meter team in Rio, recorded the world's second fastest time this season to win the women's 200-meter individual medley going away in 2:10.43, 3.55 seconds ahead of Canada's Sarah Darcel. Great Britain's Hannah Miley was third in 2:15.51.
Ashley Twichell closed out the women's events by winning the 800-meter freestyle in 8:36.17, 2.32 seconds ahead of Argentina's Delfina Pignatiello. Swimming just a short drive from her home in Carmel, Indiana, Emma Nordin was third in 8:46.32.
Cody Miller, the Olympic bronze medalist in the 100-meter breaststroke, got the men into the medal production by finishing second in a race where silver was more like gold. Great Britain's Adam Peaty, the Rio Olympic champion and world record holder who has dominated the event the past three years, won in 58.86. Miller touched second in 1:00.30, edging out Italy's Nicolo Martinenghi by 0.03. Kevin Cordes, Miller's teammate in Brazil, was fourth in 1:00.43., while Nic Fink was fifth, in 1:01.00.
Jacob Pebley was second for the second time this weekend, backing his Friday finish in the 200-meter backstroke with another in the men's 100 back. Xu Jiayu continued his dominance, posting the top time in the world this season with a 53.04 while Pebley touched in 53.77. Grigory Tarasevich, a Russian who competes at the University of Louisville, was third in 53.96.
Josh Prenot won his second race of the meet by chasing down teammate Michael Andrew over the final 50 meters of the men's 200 IM. Silver medalist in the 200-meter breaststroke in Rio, Prenot stormed back to win in 1:58.93, adding to his win Thursday in the 200 breast and Friday's second-place finish in the 400 IM. Andrew, a 17-year-old from Aberdeen, South Dakota, shaved 0.07 seconds off the junior world record with his time of 1:59.12. Daiya Seto of Japan was third, 1.42 off the winning pace.
Andrew Abruzzo closed out the meet by turning a 0.16 deficit with 300 meters left in the men's 1,500-meter into a victory with a personal best of 15:13.95, 1.64 seconds ahead of Great Britain's Tom Derbyshire. Stephen Milne took third in 15:20.01 as British swimmers took three of the top four spots.


text:
{ "type": "ExternalData", "service": "geoline", "ids": "Q22401819", "properties": { "stroke": "#3b78cb", "stroke-width": 1 } }
Der Kiglikavik Lake ist ein See im Westen des kanadischen Territoriums Nunavut, in der Kitikmeot-Region.

Lage
Der Kiglikavik Lake liegt in einer Tundralandschaft im Norden Kanadas. Er besitzt eine Wasserfläche von 130 km². Der  hoch gelegene See ist 90 km von der Meeresküste des Coronation Gulf entfernt. Der 38 km lange See ist in zwei größere Wasserflächen gegliedert. Der Tree River entwässert den See an dessen nordwestlichen Ufer.

Weblinks
 Kiglikavik Lake bei Natural Resources Canada

Einzelnachweise

See in Nunavut
See in Nordamerika
SKiglikavik Lake


The 55g size of Toppik Hair Fibers would be enough to last approximately 120-150 days depending on how much you of the Fibers you use.
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Toppik is the instant solution for thinning or balding hair and is suitable for both men and women. Toppik Hair Fibers are not a cream, spray or cover-up but is in fact made of the same proteins – keratin – as your own hair.
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text:
Alice Pung, Australia, Australian Women Writers Challenge, Author, AWW2019, Black Inc, Book review, Cambodia, memoir, Non-fiction, Publisher, Setting, TBR40
'Her Father's Daughter' by Alice Pung
April 17, 2019 April 25, 2019 kimbofo
Non-fiction – memoir; Kindle edition; Black Inc; 254 pages; 2013.
It seems fitting to review Alice Pung's memoir Her Father's Daughter on the 44th anniversary of the end of the Cambodian Civil War (17 January 1968 – 17 April 1975) and the beginning of a new deadly period in Cambodian history.
When the war ended, the Communist Party of Kampuchea (aka the Khmer Rouge) took power. During its four-year reign, the Khmer Rouge arrested, tortured and executed more than a million citizens in what is now known as the Cambodian genocide. (Around a million more died of disease and starvation.)
Alice Pung, an Australian-born writer, editor and lawyer, is the daughter of two Cambodians who fled the killing fields of the Khmer Rouge. Her parents sought asylum in Australia in 1980, and this memoir charts Alice's early adulthood when she unearths the story of her father's frightening past and comes to understand some of his peculiar, over-protective behaviours.
A startling story
Her Father's Daughter is a startling and often beautiful story, grim in places but also warm and funny and heartfelt — and totally engrossing.
Unusually for a memoir, it is written in the third person (perhaps, I suspect, to provide some emotional distance for the writer), which lends it an other-worldly, almost fictional, feel.
Her father had named her Alice because he believed this new country to be a Wonderland, where anything was possible if only she went along with his unfailing belief. His patriotism rang truer and more annoying than any bogan supremacist's. 'Australians all let us rejoice, for we are young and free.' This to him was the most beautiful national anthem in the world. There was golden soil and wealth for toil. Who wanted to be anywhere else? In other countries, where their anthems were all about rinsing the land in blood of the brothers?
It examines Pung's growing realisation that her father has been deeply traumatised by past events at the same time that she, herself, is trying to stand on her own two feet as a young independent woman. Keen to forge out on her own, she's often annoyed by her father's meddling, his inability to understand her need to travel and explore the world, his hurt when she won't heed his advice to settle down and get married, to eschew a potential career in law for one helping him run his Retravision store.
To live a happy life, he believes, you need a healthy short-term memory, a slate that can be wiped clean every morning, like one of those toys he bought for his daughter when she was young – an Etch A Sketch. If you turned it upside down and shook it, your art disappeared.
It's only when she begins to dig into her father's story that she is able to understand that his fears for her future and her happiness come from a very dark place. She travels to China and Cambodia, meeting family members and other survivors, and hearing their harrowing tales of deprivation, torture and survival.
There is a lot of death in this story, but there are funny moments too. Pung paints her father as a quirky character with odd character traits, but she does so with fondness and respect. It reads very much as a love letter to him.
And the prose, so astonishing in its clarity of thought and vision and honesty, in its preparedness to discuss difficult topics, is often wry and always original. Her sentences have a dark beauty to them, as these examples show:
His parting gift was a pomegranate from his travels. He gave her an orb of perfect seeded gems encased in incarnadine, but inside her ribcage was rotting fruit.
She didn't feel too independent. There had been hours of loitering alone, feeling lost, feeling like there were feral kittens fighting in her solar plexus.
The skies were clear then too, and the stars winked like unforgiving blades.
Courageous tale
I really loved this story, for its honesty, its courage, its inspiration and its love. In exploring her own Asian roots and telling her father's own troubled history, Pung has crafted a powerful story about tenacity, family heritage, intergenerational trauma — and hope.
Her Father's Daughter was shortlisted for numerous awards in Australia and won the Non-Fiction Prize in the 2011 Western Australian Book Awards.
For another take on this book, please see Karenlee Thompson's eloquent review, which has been posted on Lisa's blog.
If you liked this, you might also like:
'First They Killed My Father: A Daughter of Cambodia Remembers' by Loung Ung: an emotionally wrenching memoir about Ung's traumatic childhood under the Khmer Rouge.
This is my 15th book for #TBR40 and my 8th book for #AWW2019
Tagged Alice Pung, Australian literature, Australian women writers, AWW2019, genocide, memoir, TBR40
Previous post'The Governesses' by Anne Serre
Next post3 page-turning reads by Chip Cheek, Sabine Durrant and Rob Hunter
5 thoughts on "'Her Father's Daughter' by Alice Pung"
Cathy746books says:
It sounds like the third person narration works really well here. Fascinating stuff
I loved the third person narration. It makes the story so readable and it also helps the author put herself in her father's shoes because she goes back in time to tell some of his story before she was even born.
Pingback: Six Degrees of Separation: From 'Redhead by the Side of the Road' to 'Song for an Approaching Storm' – Reading Matters
Pingback: 'One Hundred Days' by Alice Pung – Reading Matters


text:
require_relative '../../../../lib/noteshare/interactors/web/searcher'
require 'pry'

module Web::Controllers::Documents
  class Search
    include Web::Action
    include Noteshare::Interactor::Search

    expose :documents, :nodes
    expose :active_item

    def do_command(search_key)
      if search_key and search_key[0] == '!'
        command = search_key[1..-1]
        puts "in do_command, search_key = #{search_key}".cyan
        redirect_to "/admin/process_command?#{command}::#{ENV['COMMAND_SECRET_TOKEN']}"
      end
    end

    def call(params)
      # binding.pry
      @active_item = 'reader'
      search_key = params['search']['search']

      puts "search_key = #{search_key}".red
      do_command(search_key)

      search_key_parts = search_key.split(' ')
      command = search_key_parts[0]
      commands = AdvancedSearcher.new().commands
      puts "commands = #{commands}".red
      puts "command = #{command}".red
      puts "search key = #{search_key}".red
      puts "search_key_parts = #{search_key_parts}".cyan
      if command and commands.include? command
        result = AdvancedSearcher.new(search_key, current_user2).call
        @documents = result.documents
        @nodes = []
      else
        result = Searcher.new(params, current_user2).call
        @documents = result.documents
        @nodes = result.nodes
      end

    end

  end
end

# search_local(user, key, limit: 20)

redpajama_set_name: RedPajamaGithub


text:
About Mike Sivier
Know Your MP!
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~ politics for the people
Theresa May's authority undermined as high court says MPs must approve Brexit
Posted by Mike Sivier in Brexit, European Union
Brexit, Conservative, EU, european union, government, Lord Chief Justice, Parliament, ruling, sovereignty, Theresa May, UK, undermine, United Kingdom
The challengers maintained that parliamentary approval and legislation was required for such a fundamental change [Image: Daniel Leal-Olivas/PA].
How unexpected! The high court has undermined Theresa May's authority in a fundamental way.
She has made herself perfectly clear – as Tory prime ministers seem to love saying – that the UK's departure from the European Union would be triggered by her Tory government, when it was ready.
Now the Lord Chief Justice has told her she is wrong – and in no uncertain terms.
Think about that: A prime minister who does not understand the law.
By what authority does she govern, then?
And, if she is wrong about this, what other mistakes is she making?
This Blog has already pointed out that Mrs May's 'Great Repeal Bill' is in fact nothing of the sort, as it enshrines a multiplicity of EU rules in UK law – rules that we already thought had been approved by Parliament, so the reason is hard to determine.
And we keep hearing about Tory ministers being rebuffed by EU representatives for trying to make deals that are – let's call them – inappropriate.
They are hedging their bets, as much as they possibly can – and finding that they have much less leeway than they expected.
Now it seems even the British legal system is against these corner-cutting Tories.
The ruling has been handed down in response to the so-called "People's Challenge" to the government's Brexit plans, brought by a group including Gina Miller.
To be honest, this is a major surprise as a Northern Irish court had ruled that Parliament need not be asked to trigger Brexit. But it was only ruling on issues relating to Northern Ireland.
Reactions have been as you might expect. Nigel Farage is talking in terms of "betrayal", suggesting that an attempt to overturn the result of the EU referendum might be on its way – but would face the wrath of the UK's electorate.
That might be wishful thinking on his part! The electorate has been dealt ample evidence that the arguments for leaving the EU were not worth the time spent to utter them and full Parliamentary scrutiny may highlight these discrepancies even more.
The fact is that the referendum result is now confirmed as merely advisory, though.
Labour's Jeremy Corbyn has adopted what seems the right attitude to take. He said the government must now take its plans to Parliament and remove the shroud of secrecy that has hung over them ever since the result of the referendum became known.
This could be another source of humiliation for Mrs May as it has long been suspected that she and her ministers don't have a plan at all.
Parliament alone has the power to trigger Brexit by notifying Brussels of the UK's intention to leave the European Union, the high court has ruled.
The judgment, delivered by the lord chief justice, Lord Thomas of Cwmgiedd, is likely to slow the pace of Britain's departure from the EU and is a huge setback for Theresa May, who had insisted the government alone would decide when to trigger the process.
The Lord Chief Justice said that "the most fundamental rule of the UK constitution is that parliament is sovereign".
A government spokesman said that ministers would appeal to the supreme court against the decision. The hearing will take place on December 7 – 8.
Source: Setback for Theresa May as high court says MPs must approve Brexit | Politics | The Guardian
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9 thoughts on "Theresa May's authority undermined as high court says MPs must approve Brexit"
WebEd said:
Roy Beiley said:
Nice to see May"s hubris deflated in this manner. She will probably sack The Attorney General for his poor advice.Liked it when Stephen Hawking criticed Brexit in front of her at the recent Childrens Awards Ceremony. She is so out of her depth she must be wondering whether it is all worth it. Hopefully she will call an Election before May deadline for Article 50.
NMac said:
Tories only understand and respect laws which favour them and their cronies. We must be prepared for the inevitable appeal with more crowdfunding.
Dai said:
No written constitution means no democracy, where would the hangers on fit into a written democratic process.
Why not leave the barons and royals run the country and resume normal service, it will make no difference to our life in servitude..
Mike Sivier said:
The UK has a written constitution – it simply isn't vested in a single document but in several.
Lin Wren said:
Not a surprise really. The only option now is to Repeal the 1972 European Communities Act. IT does not need government to do it
Now I am confused, if we have a written constitution, it should state, Parliament is sovereign, why do we need someone in a wig in a court room to confirm it..
Because the Tories had challenged it with their claims?
This sort of thing happens all the time. Someone does something that is against the civil law, so someone else challenges it in the courts and the judge(s) rule on the law.
chriskitcher said:
When are these dumb politicians going to accept the ruling of the law like all the rest of us have to. Seems to me that whenever they have a ruling against them they use our money to launch an appeal. Good job the right of Judicial Review was not stopped by Camoron and his crew.
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Evidence mounts up against the BBC's Panorama hatchet-job
Nice – an 'above inflation' pay rise for public sector workers. But is it enough?
MPs have supported bid to block Parliament suspension to allow 'no-deal' Brexit
Labour lords' 'no confidence' threat to Corbyn is shooting themselves in the foot
Lords bid to block 'no-deal' Brexit as OBR raises recession fears
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Over these babies' lifetimes, their low birth weights raise the likelihood they will suffer poorer health and lower achievement, including reduced earnings and educational attainment.
Nationally, the advent and expansion of hydraulic fracturing operations have reduced gasoline prices, decreased some air pollution emissions and driven down U.S. dependence on foreign oil. But in areas surrounding the nation's roughly 1.2 million fracking wells, the extraction technique has increased pollution of air, soil, groundwater and surface water.
Research by some of the new study's authors — all economists — has detailed the powerful impact of fracking on local communities, where it boosted employment, household incomes and housing values. It also has made the extraction technique's local effects on human health a subject of heated debate and growing research.
A representative of the oil and gas industry criticized the study for failing to take account of a wide range of factors that can contribute to low birth weight, as well as for measuring women's proximity to fracking wells instead of their exposure to actual pollutants.
"It's just one of many examples of research that has similar limitations," said Nicole Jacobs, Pennsylvania director for Energy in Depth, a research, education and lobbying arm of the Independent Petroleum Assn. of America.
Jacobs also cited Pennsylvania Health Department statistics showing that in the most heavily drilled counties in Pennsylvania's Marcellus Shale region, infant mortality rates not only have declined, but actually have improved more than overall state levels. To the extent that low birth weight drives infant mortality, such data would appear to contradict the findings reported Wednesday, Jacobs said.
Firming up conclusions on fracking's health effects, she added, will take years of further research. "But we're beginning to see a pattern: that living near these sites does elevate risk compared to living further away," said Finkel, who was not involved in the Science Advances study.
"Until we can determine the source of this pollution and contain it, local lawmakers will be forced to continue to make the difficult decision of whether to allow fracking in order to boost their local economies — despite the health implications — or ban it altogether, missing out on the jobs and revenue it would bring," she said.


As many of you know, Equal Pay themes are an opportunity to refocus on the gender gap in pay between women and men. It's hard to believe that even in 2018, U.S. women are still earning annually between 52 and 79 cents for every dollar men earn for the same jobs, with black women and Latinas earning less than white women.
On April 17, 2012, (While over six years ago the same issues are still relevant.) I attended the 6th Annual Equal Pay Day NYC, hosted by the New York Women's Agenda (NYWA), Equal Pay Coalition NYC (EPC-NYC), A Better Balance, and NYU Law Women. The forum presented New York Senator Kirsten Gillibrand and other NY officials championing equal pay, as well as panels and discussions on related issues such as women's representation in the Senate (only 17%!) and how many women turn out to vote (only 20% in New York, and only 46.2% across the nation).
The turnout at the event was wonderful, especially on a Monday morning, but with the dire economic situation for women, not only shown in the wage gaps but also in the low numbers of women finding employment post-recession, you would think this event would have been standing-room only, particularly in New York City.
Where are all the women . . . in elected office, in voting booths, in management, and especially at the forefront of their communities, states, and the nation, demanding change, demanding to be heard and recognized?
Are women too caught up in meeting their immediate needs to stop and look at the bigger picture? Are women unaware that this problem still exists to this extreme? Or are women simply unsure about what exactly they can do?
NYWA and EPC-NYC presented some great ideas for women to get involved and Get Even in the workplace, as put by the nonprofit organization for women and the workplace, Catalyst.
Email your governor, your senators and representatives, and your community leaders.
Talk about pay equity online, in your blog, on Facebook, Google+, LinkedIn, Twitter, etc. Turn your profile picture red because women are still in the red!
Write letters to the editor, call radio talk shows and suggest that they talk about pay equity, and start the conversation with others.
Host an Unhappy Hour with your friends to brainstorm ways to close the wage gap.
Support organizations and politicians that are actively fighting pay equity, such as those mentioned in this post.
Equal pay, equal representation, and more women leading and managing will improve the lives of families, the profits of organizations, and the national and world economy. (see "How Being Successful Can Save the Planet.") If we all commit to doing just one of these ideas—go on, put it on your calendar—we can make a difference not only in the lives and work of women but in the future of our world.
Get a sneak peek into Karen's Amazon #1 Best Seller The Ageless Way! Just enter your information below for instant access to a FREE mini-book, "The Origins of the New HERstory of Our AGE" here.


For purposes of this discussion, we'll define life insurance in to two categories: term life insurance, and permanent life insurance.
Term is known as such because once you qualify, the life insurance stays in force for a pre-determined time period; for instance, 20 years (assuming you continue to pay the premiums). Typically, once the term is up, the life insurance coverage ends.
Permanent, on the other hand, stays in force as long the insured is alive. And again, the assumption is that the premiums are paid. The most prominent types of permanent insurance are whole, variable, universal, and variable universal.
Permanent life insurance has an investment component that, in an ideal situation, can grow to a to a point that it can be used to help cover premium expenses, serve as a tax-advantaged potential source of cash, or be liquidated when the money is needed more than the life insurance coverage.
Based on the aforementioned description, you might wonder why someone would forego the additional benefits of permanent life insurance, and instead choose a term policy.
The primary reason is the cost. The premiums for permanent life insurance can often be several times the cost of a term policy. Which is fine, if you're in a situation that calls for consideration of a permanent policy (such a owning business, and/or wishing to offset potential estate taxes).
But the people who usually are (or should be) shopping for life insurance are younger parents, trying to make sure that they aren't around, the loss to the children is emotional, but not financial.
By definition, younger parents usually need a sizable death benefit (at least 200 times their typical monthly expenses), yet don't have enough free cash around to pay for a suitable amount of permanent life insurance coverage.
Therefore, a term policy is usually more suitable, and should remain in effect at least until the kids are out of the house and supporting themselves. And a policy should be obtained on the lives of both working and stay-at-home parents.
Many workers have some term life insurance coverage through their job, often with a death benefit that equals one to three times the worker's annual earnings.
But there are several drawbacks to this arrangement. First, that coverage isn't likely to be enough to cover what loved ones would need if the worker were to die.
Second, group life insurance policies often charge healthy people more than what the workers would pay if they purchased their own life insurance.
Finally, the group life insurance coverage may stop if the worker stops working for the employer. By that time, the worker may have suffered a health condition that may make obtaining new life insurance difficult, or even impossible.
The first place to look for your own term life insurance policy is www.term4sale.com. The site allows you to anonymously compare offerings from several different insurers, and in several different permutations of coverage length and death benefit amount.
If you already have an agent whom you know and trust, ask him or her for a quote (just make it clear that you're interested in term life insurance only, if that is indeed the case).
If you need to find an agent in your area, you can search for and contact an independent one at www.trustedchoice.com.
Just don't be surprised if they don't return your call right away. They're probably still out celebrating.


text:
Q: Dialog.show does not display with Codename One, NetBeans and Java using NetBeans 7.4 and Java, Dialog.show("x","y","YES","NO"); won't display. I'm following Codename One's Hello World demo as an example.

A: Codename One seems to be a Java framework for generating platform independent UIs for mobile devices. I just downloaded the plugin for Netbeans 7.4 via Tools->Plugins.
I generated a demo project from scratch and looked through the code.
There is a class in the package userclasses called StateMachine. I put your code sample into the initvars method. Looks now like this:
protected void initVars(Resources res) {
    Dialog.show("x","y","YES","NO");
}

Running this little demo, I got the dialog shown instantly.
Hope this helps.