text:
Add this line to your application's Gemfile:

    gem 'phabricator'

And then execute:

    $ bundle

Or install it yourself as:

    $ gem install phabricator

## Usage

### Configuration

You can configure Phabricator to use a specific host, user, and cert. Otherwise,
it will fall back to whatever is in your `~/.arcrc` file.

```ruby
Phabricator.configure do |c|
  c.host = 'secure.phabricator.com'
  c.user = 'amber'
  c.cert = '<CERT>'
end
```

### Projects

```ruby
# Find the project given a project name.
Phabricator::Project.find_by_name('Project')
```

### Tasks

```ruby
# Create a Maniphest task.
Phabricator::Maniphest::Task.create('title')

# Create a Maniphest task with more detail.
Phabricator::Maniphest::Task.create('title', 'description', ['Project'], 'normal')
```

### Contributing

Patches welcome! (:

For a list of Conduit methods available, see http://secure.phabricator.com/conduit.

redpajama_set_name: RedPajamaGithub


text:
Press conference to kick-off FREE summer instruction and activities for San Diego Unified students
25 May 2021 | SDF |
| Level Up SD
What: Press Conference
When: Wednesday, May 26
Time: 10:00 – 11:00 a.m.
Where: Elementary Institute of Science, 608 51st Street, San Diego, 92114
Why: Starting Wednesday (May 26) parents can register San Diego Unified students for teacher-led instruction and summer activities offered by more than 65 local nonprofits at www.levelupsandiego.org. All instruction and activities are FREE.
Joe Vasquez (Host/Emcee), Board Member, Elementary Institute of Science
Pamela Gray Payton, Vice President, Chief Impact and Partnerships Officer, The San Diego Foundation
Carol Dedrich, CEO, Girl Scouts San Diego
Dr. Pamela Thompson, Principal, Nye Elementary
Dr. Sharon Whitehurst-Payne, Board Vice President, San Diego Unified School District
Richard Barrera, Board President, San Diego Unified School District
Podium shots as well as graphics showing the more than 65 local nonprofits who received Level Up SD grants to offer San Diego Unified students a summer of learning and joy.
Level Up SD was created this year by the San Diego Unified School District and The San Diego Foundation thanks to a $31 million commitment by the San Diego Unified Board of Education. It features in-person classroom instruction in the mornings at neighborhood schools with San Diego Unified teachers and afternoon summer activities offered by dozens of local nonprofits in communities across the city. Level Up SD is part of a comprehensive effort by San Diego Unified to help provide area students with a summer of learning and joy to prepare them academically and emotionally for the fall.
Already, 20,000 students have signed up for instructional opportunities in the morning at neighborhood schools with San Diego Unified teachers, and even more are expected to participate in the summer activities and opportunities beyond the classroom hosted by more than 65 local nonprofits. #LevelUpSD
About Level Up SD
Created this year by the San Diego Unified School District and The San Diego Foundation, Level Up SD, a Summer of Learning and Joy features in-person classroom instruction in the mornings at neighborhood schools with San Diego Unified teachers and summer activities offered by dozens of nonprofits in communities across the city. There is no cost to families for the classroom instruction or the activities, thanks to a $31 million commitment by the San Diego Unified Board of Education. To be eligible for #LevelUpSD, students must be enrolled in San Diego Unified for the 2021-2022 school year.
Summer school generally is offered to a select group of struggling students. Level Up SD is open to all K-12 students. This means thousands of kids from every corner of our community can now take advantage of academics and free activities beyond the classroom, like learning to kayak or learning to fly a drone, for the first time
About The San Diego Foundation
The foundation inspires enduring philanthropy and enables community solutions to improve quality of life in our region. For more than 45 years, The Foundation and its donors have granted more than $1.3 billion to support nonprofit organizations and strengthen the San Diego community. Learn more at SDFoundation.org.
About San Diego Unified School District
The second largest school system in the State of California and fastest improving school district in the nation, San Diego Unified students have earned a reputation for hard work and achievement. This success was recently recognized when President Biden selected San Diego Unified Superintendent Cindy Marten to serve as his Deputy Secretary of Education. Despite the national recognition, San Diego Unified remains firmly rooted in the communities it serves. "Our schools make San Diego a better place" is more than a slogan. It is a systemwide commitment to San Diego's "City of Villages" growth strategy, where every neighborhood is home to a high-quality public school. To learn more, follow #BetterSD and visit sandiegounified.org.
Tony Manolatos, Manolatos Public Affairs, tony@manolatospa.com, 619-549-0137
Maureen Magee, San Diego Unified School District, mmagee@sandi.net
Theresa Nakata, The San Diego Foundation, theresan@sdfoundation.org
San Diego Foundation Offers $3.5M…
San Diego Foundation, Dr. Seuss…
Level Up SD Invites Local…
San Diego Foundation Grows Local…

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: Generate date sequences in a dataframe with variable lengths for each group of duplicated data I have a dataframe and have duplicated rows based on the difference between two dates: Date (date of collection of samples) and hatch (date of birth) using the following code. Difference (basically lifespan in months) ranges from 4-12 months:
library(zoo)
test$difference <- 12 * as.numeric(as.yearmon(test$Date) - as.yearmon(test$hatch))

test$difference <- ceiling(test$difference)
test2 <- test[rep(row.names(test), test$difference),]

I need to create a sequence for each specimen (each of which has a unique serial number, sn) starting from the hatching date, increasing in 1 month increments and with the length out equal to the value in the differences column. I tried a loop but I could not work out how to phrase it as I'm quite new to R.
At the moment the dates are in the format %Y-%m-%d but I'm only interested in the month and year groupings.
Any insights would be really useful :)
    structure(list(Sex = structure(c(3L, 3L, 3L, 3L, 3L, 3L, 3L,
3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L), .Label = c("F", "J", "M"), class = "factor"),
    Maturity = c(5L, 5L, 5L, 5L, 5L, 5L, 5L, 5L, 5L, 5L, 5L,
    5L, 5L, 5L, 5L), XLength = c(12, 12, 12, 12, 12, 12, 12,
    12, 12, 16.5, 16.5, 16.5, 16.5, 16.5, 16.5), Weight = c(44.1,
    44.1, 44.1, 44.1, 44.1, 44.1, 44.1, 44.1, 44.1, 73.6, 73.6,
    73.6, 73.6, 73.6, 73.6), Ringcount = c(232L, 232L, 232L,
    232L, 232L, 232L, 232L, 232L, 232L, 225L, 225L, 225L, 225L,
    225L, 225L), Date = structure(c(10480, 10480, 10480, 10480,
    10480, 10480, 10480, 10480, 10480, 10480, 10480, 10480, 10480,
    10480, 10480), class = "Date"), hatch = structure(c(10248,
    10248, 10248, 10248, 10248, 10248, 10248, 10248, 10248, 10255,
    10255, 10255, 10255, 10255, 10255), class = "Date"), sn = c(1,
    1, 1, 1, 1, 1, 1, 1, 1, 2, 2, 2, 2, 2, 2), difference = c(9,
    9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9)), .Names = c("Sex",
"Maturity", "XLength", "Weight", "Ringcount", "Date", "hatch",
"sn", "difference"), row.names = c(NA, 15L), class = "data.frame")

A: 1) Assuming you want to add a new column with the dates, using test we can write the following.  It uses no packages.
Seq <- function(h) seq(h[1], length = length(h), by = "month")
transform(test, dates = ave(hatch, sn, FUN = Seq))

giving:
   Sex Maturity XLength Weight Ringcount       Date      hatch sn difference      dates
1    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 1998-01-22
2    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 1998-02-22
3    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 1998-03-22
4    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 1998-04-22
5    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 1998-05-22
6    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 1998-06-22
7    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 1998-07-22
8    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 1998-08-22
9    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 1998-09-22
10   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 1998-01-29
11   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 1998-03-01
12   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 1998-03-29
13   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 1998-04-29
14   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 1998-05-29
15   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 1998-06-29

2) Alternately if you just want year and month use yearmon class from zoo.
library(zoo)

Seq_ym <- function(h) h[1] + (seq_along(h) - 1) / 12
transform(test, dates = ave(as.yearmon(hatch), sn, FUN = Seq_ym))

giving:
   Sex Maturity XLength Weight Ringcount       Date      hatch sn difference    dates
1    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 Jan 1998
2    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 Feb 1998
3    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 Mar 1998
4    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 Apr 1998
5    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 May 1998
6    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 Jun 1998
7    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 Jul 1998
8    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 Aug 1998
9    M        5    12.0   44.1       232 1998-09-11 1998-01-22  1          9 Sep 1998
10   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 Jan 1998
11   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 Feb 1998
12   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 Mar 1998
13   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 Apr 1998
14   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 May 1998
15   M        5    16.5   73.6       225 1998-09-11 1998-01-29  2          9 Jun 1998

redpajama_set_name: RedPajamaStackExchange


text:
Sept. 28, 2015 / 9:37 AM
UPI horse racing roundup
Robert Kieckhefer, UPI Racing Writer
Onus wins Commonwealth Oaks Saturday, 26 September, at Laurel Park in Maryland. (Laurel Park photo)
Some budding stars -- Songbird, Smooth Roller, Wedding Toast, Nyquist and Rock Fall -- joined the likes of super mare Beholder and Big Blue Kitten in winning weekend qualifying races for the upcoming Breeders' Cup.
Things get even more hectic next week with 12 Breeders' Cup "Win and You're In" races -- at Keeneland, Santa Anita and Belmont Park -- and the climax of the Florida Sire Stakes at Gulfstream Park.
On the international front, 2-year-olds were all the rage at Newmarket, also with some stars in the making. And, in Australia, it was another tight finish as the spring classics loom on the horizon. Next week, Group 1 action returns to Japan with the Sprinters Stakes -- a leg of the Global Sprint Challenge.
Geothermal and Isotherm both won stakes races on Saturday. Sounds cool. But both words have to do with heat and those who had both of them on top were hot, indeed.
Speaking of hot, how about Beholder?
Beholder easily disposed of seven would-be rivals in the stretch run of Saturday's $300,000, Grade I Zenyatta Stakes at Santa Anita. Jockey Gary Stevens barely had to ask the super mare as she won by 3 1/4 lengths, well in hand, while finishing 1 1/16 miles on a fast track in 1:42.83. My Sweet Addiction and Savings Account filled out the trifecta at big odds. Stevens said trainer Richard Mandella "told me yesterday, 'I want to win but by no means do I want to knock her out.' We couldn't have scripted it any better. I told him that he might have to tack-walk her in the morning because she pulled up full of it." Stevens was fanned wide on the first turn and simply elected to take that position and keep Beholder out of potential trouble rather than drop in and save ground. She was on the outside again turning for home. The victory provided a needed -- and well-paid -- workout for the 5-year-old Henny Hughes mare and did nothing to deter Mandella from his inclination to bypass the Breeders' Cup Distaff, which Beholder won in 2013, in favor of the Classic. She easily beat males in the Grade I Pacific Classic last month at Del Mar and Mandella said the Breeders' Cup Classic, right now, "would be the plan. Anything can change and nothing's in stone, but as of now there's no reason not to think of that." The Keeneland race, however, will feature stiffer competition. Beholder now has won six straight races and 10 of her last 11. The race was a "Win and You're In" for the Distaff but Beholder already had secured a spot in either the Distaff or the Classic by virtue of wins earlier in the year.
Out East, it was all Wedding Toast in Saturday's $400,000, Grade I Beldame Stakes at Belmont Park. The 5-year-old Street Sense mare took the lead right out of the gate and won comfortably by 2 3/4 lengths over Curalina. Catch My Drift was third. Wedding Toast, owned by Godolphin and trained by Kiaran McLaughlin, ran 9 furlongs around one turn on the big Belmont oval in 1:47.67 under Jose Lezcano. She won the Grade II Ruffian and the Grade I Ogden Phipps in her two previous starts, showing marked improvement in each. McLaughlin said of his conversation with Lezcano, "I don't say it very often, but I asked him not to give her a hard race if he didn't have to because she looked that good on paper. We have a big race in five weeks. Couldn't have asked for better, it really went perfect." He said Wedding Toast likes the one-turn race but should have no trouble handling two turns in the Breeders' Cup Distaff at Keeneland.
Include Betty, already a multiple graded stakes winner on the East Coast, rallied from last of six to win Sunday's $200,000 Remington Park Oaks in Oklahoma. But she had to work for it, winning a tough stretch tussle with Sweet Opportunity by only 1/2 length after veering left. Harlan's Romance finished third. Include Betty, an include filly, got 1 1/16 miles on a fast track in 1:44.83 with Drayden Van Dyke in the irons but had survive a claim of foul before the result was made official. Van Dyke said Include Betty tends to loaf when she gets the lead and he had to apply the stick to keep her focused. "I really didn't want to hit her," he said. "But I had to and when I put my stick to her, she went down to the left a little bit." She won the Grade I Mother Goose in June, then finished third in the Grade I Coaching Club American Oaks and fifth in the Grade I Alabama at Saratoga.
Put a ring around the name Smooth Roller. The 4-year-old Hard Spun colt, making just his fourth career start, surged by pacesetting Bayern in the lane in Saturday's $300,000, Grade I Awesome Again Stakes at Santa Anita and went on to win by 5 1/4 lengths. Hoppertunity was up for second, 1 1/2 lengths ahead of Bayern, giving trainer Bob Baffert the bottom two-thirds of the trifecta. Smooth Roller, with Tyler Baze up for trainer Victor Garcia, ran 1 3/8 miles on a fast track in 1:48.08. He started his career in June, winning a maiden event handily at Santa Anita, then took an optional claimer at Del Mar in August. He stumbled at the start of the Harry F. Brubaker Stakes and rallied to finish fourth, beaten just over 1 length in his only other race. "I expected him to run big," Garcia said. "He had a lot of trouble in his last race. He was washed out, stumbled from the gate, was four or five wide both turns and only got beat a length and a quarter. I worked the horse twice and he worked real good. Tyler was real happy with it. We'll go to the Breeders' Cup. Absolutely." The race was a "Win and You're In" for the Breeders' Cup Classic. Martin Garcia, who rode last year's Classic winner, Bayern, said his mount is not the same horse he was a year ago. "If he was the same, he would have won," Garcia said. "Too quiet. He didn't show anything."
Geothermal was set down for the long stretch drive in Saturday's $175,000 Lukas Classic at Churchill Downs and responded perfectly, dueling to the lead and drawing off late to score by 1 1/2 lengths over the favorite, Departing. Smack Smack finished third. Geothermal, a 6-year-old gelding by Unbridled Energy, ran 9 furlongs on a fast track in 1:49.93 with Robby Albarado up. While he's unlikely to scare off American Pharoah, he has been improving while climbing the class ladder this season. "This horse has been doing better," said winning trainer Steve Margolis. "He's a gritty little horse. Ever since the Fair Grounds, he has run well on the turf but we looked back on his numbers and his numbers have been so much better on the dirt and he's healthy now - he's sound." He said he hasn't plotted the next step for Geothermal.
Shotgun Kowboy, the local favorite, outran all the invaders and one-time Triple Crown contenders to take Sunday's $400,000, Grade III Oklahoma Derby at Remington Park. The Kodiak Kowboy gelding, with Cliff Berry up, dueled New York invader Classy Class into submission, surged to the lead in the stretch and held off California-trained Desert Dynamo by 1/2 length. Among the better-known rivals, Souper Colossal finished fourth, The Truth Or Else seventh and Tale of Verve eighth. Shotgun Kowboy ran 9 furlongs on a fast track in 1:48.91, winning for the fifth time in seven starts -- all at Remington Park. The Derby was only his second start as a 3-year-old. He was bred by his owner and trainer, C.R. Trout. "I wanted him to get out of the gates good and I was surprised I was there," said Berry, who plans to retire after the Remington meeting. "I took a big hold of him but nobody came up to him. He was cruising so I let him do it."
The final margin didn't reflect it but Rock Fall seemed in charge all the way in Saturday's $400,000, Grade I Vosburgh Stakes at Belmont Park. After pressing the pace three-wide into the stretch, the 4-year-old battled to a narrow lead with a sixteenth to run and won by a neck. Salutos Amigos was second, a head in front of Stallwalkin' Dude and another 1/2 length better than Palace. But Rock Falls seemed determined as he scored his seventh straight win, running 6 furlongs on a fast track in 1:08.70 with Javier Castellano up. In his previous start, he won the Grade I A.G. Vanderbilt at Saratoga, beating The Big Beast, a rugged customer, by a nose. "He's blessed with a lot of natural talent but to go along with that he's got a lot of fight, which is great," said winning trainer Todd Pletcher. "I wanted to get this one and still have something for the Breeders' Cup, so I was hoping I didn't cut it too close and he pulled it out. It's a fine line between running well in the prep and hoping you have something left for the Breeders' Cup." The Vosburgh was a "Win and You're In" for the Breeders' Cup Sprint.
Valid had to battle down the stretch inside Falling Sky in Saturday's $75,000 Groomstick Stakes at Gulfstream Park before finally prevailing by a neck over that rival as the odds-on favorite. Grande Shores was along late to finish third. Valid, a 5-year-old Medaglia d'Oro gelding, ran 7 furlongs on a fast track in 1:22.87 with Matthew Rispoli in the irons. Asked about the Breeders' Cup, trainer Marcus Vitali said, "We're talking about it. It's a conversation that (the owners) and I will have. We'll see how he comes out of this and put him back in training and we'll make a decision." He would have options as Valid won the Grade III Philip H. Iselin Handicap at Monmouth Park going 9 furlongs in his previous start.
Ivan Fallunovalot stalked the pace in Sunday's $150,000 Remington Park Sprint Cup, rallied by the leaders three-wide and went on to win by 2 1/2 lengths over Candip. Imahit was up for third. Ivan Fallunovalot, a 5-year-old Texas-bred gelding by Valid Expectations, ran 6 furlongs on a fast track in 1:08.42 with Calvin Borel at the controls. He now has been first or second in 10 of his last 11 starts with the only break in that skein a fourth-place finish in last year's edition of this race. "He left there running today," Borel said. "The last time, I think it was the lights, he kind of looked around and then took off. Today he left and sat right off of them just like we wanted and finished. If he goes to the Breeders' Cup, I'll be there."
Filly and Mare Sprint
La Verdad showed the way in Saturday's $300,000, Grade II Gallant Bloom at Belmont Park, saved ground and held off Wavell Avenue at the end by 1/2 length. Dame Dorothy finished third after lunging at the start. La Verdad, a 5-year-old daughter of Yes It's True, ran 6 1/2 furlongs on a fast track in 1:15.16 under Jose Ortiz. She is undefeated in five starts this season, with the earlier wins including the Grade II Distaff Handicap, the Grade III Vagrancy and the Grade II Honorable Miss. She missed some training time at Saratoga and trainer Linda Rice said she needed the race. "I've had to work hard to get her here and we lost some time, but I think this race will do her a lot of good. She'll move forward and will be harder to beat next time," Rice said.
Big Blue Kitten got first run to the lead in Saturday's $600,000, Grade I Joe Hirsch Turf Classic at Belmont Park as frontrunning Shining Copper faded. And the 7-year-old Kitten's Joy ridgling made the late advantage stand, holding off Slumber at the end for a 3/4-length victory. Twilight Eclipse, caught in traffic on the turn, was only a nose farther in arrears and the favorite, Red Rifle, settled for fourth. Big Blue Kitten, a multiple Grade I winner, finished 1 1/2 miles on firm turf in course-record time of 2:23.39 with Joe Bravo at the controls. The winner just missed in his last try, losing the Grade I Arlington Million by a nose to The Pizza Man. Overall, he now has 14 wins, eight seconds and four thirds from 29 starts. Chad Brown trains Big Blue Kitten, Slumber and Shining Copper. The top two, he said, "ran terrific. Today, Big Blue Kitten got the better of Slumber at a mile and a half. I'm proud of both horses. The race pretty much went the way I expected ... We're in the process, these last round of preps, of trying to identify horses who belong in the Breeders' Cup. A horse like Big Blue Kitten would be one, and we have a big weekend of racing both here and at Keeneland next weekend." The race was a "Win and You're In" for the Breeders' Cup Turf.
Cougar Ridge rallied three-wide down the stretch to win Sunday's $100,000 Remington Green Stakes at Remington Park by 1 length over Code West. Greengrassofyoming led briefly in the lane but finished third. Cougar Ridge, a 5-year-old Johannesburg gelding, ran 9 furlongs on firm turf in 1:47.06 with C.J. McMahon riding.
Filly & Mare Turf
Photo Call had her picture taken after upsetting Saturday's $300,000, Grade I Rodeo Drive Stakes for fillies and mares at Santa Anita. The 4-year-old, Irish-bred Galileo filly waited comfortably behind the early pace, got through between rivals with a sixteenth to run and won off by 2 1/4 lengths over Elektrum. Stormy Lucy was third and the favorite, Hard Not to Like, finished a dull eighth. Photo Call ran 1 1/4 miles on firm turf in 2:00.76. Winning rider Drayden Van Dyke said the stretch run was "a bit hairy" when a hole on the rail vanished before he could get through it. "I had to cut back and luckily she was brave enough to go through. Not a lot of fillies are brave enough to go through a hole like that but she just rocketed through there and I was lucky to get the good trip. Photo Call was last seen winning the Grade III Violet at Monmouth Park -- just her second win since arriving from Ireland last fall. Anne Sinchak, assistant to winning trainer Graham Motion, noted the race is a "Win and You're In" for the Breeders' Cup Filly & Mare Turf.
Onus stalked the pace in Saturday's $150,000, Grade III Commonwealth Oaks at Laurel Park, surged to the lead as the field turned for home and romped home first by 4 1/2 lengths. Lola Beaux was best of the rest, a nose in front of Stormy Regatta and another neck better than Rainha Da Bateria. Onus, a daughter of Blame out of the Forestry mare Silviculture, ran 9 furlongs on firm turf in 1:47.12 with Forest Boyce up. She has won three straight races, all at Laurel, starting with her first career win on July 1. "The last couple times I've been amazed how talented she is," said winning owner Stuart Janney III. "A horse that can carry on so easily just off the pace and then quicken like she does is very tough to beat." He said Onus likely will be put away for the winter but could run once more this fall "if there's another race that fits her."
Turf Sprint
Singing Kitty was along late to upset Saturday's $75,000 Unzip Me Stakes for 3-year-old fillies down the Santa Anita Hillside, besting Spirit of Xian by 1 1/4 length and the favorite, Curlin's Fox, by the same margin again. Singing Kitty, a daughter of Minister's Wild Cat, ran the gravity-assisted 6 1/2 furlongs in 1:13.34 with Rafael Bejarano in the irons. Claimed for $32,000 last December, Singing Kitty now has three wins and a second from seven starts this year with earning of more than $250,000.
Turf Mile
Alert Bay swung four-wide into the stretch in Sunday's $200,000, Grade II City of Hope Mile at Santa Anita and outfinished Big Cazanova to win by 1 length. It was another 1 1/2 lengths back to the favorite, Avanzare. Alert Bay, a 4-year-old City Zip gelding, finished 1 mile on firm going in 1:33.58 with Martin Garcia in the irons. He frequently has been in the money in stakes from New Mexico to Santa Anita to Golden Gate to Emerald Downs. "We had a tough time getting him going this year, getting back to form," said winning trainer Blaine Wright. "It's almost like the switch gets flipped ... I really hope the Breeder's Cup is a possibility. This race should certainly let us think about it."
Saham rallied from last of nine to win Saturday's $100,000, Grade III Jefferson Cup for 3-year-olds at Churchill Downs, defeating Watchyourownbobber by 3/4 length. Wayward Kitten was third and the favorite, Nun the Less, finished seventh as the field bunched up in the final yards. Saham, a Lemon Drop Kid colt, ran 1 mile on firm turf in 1:37.76 with Joe Rocco Jr. at the controls. It was his first win since his maiden victory in Florida in February. "I don't know where we would go next, to be honest," said winning trainer Brendan Walsh. "We ran him last at Indiana Grand and this was probably the main aim for the whole year. We might try to run him once more this year seeing as though he is on top of his game, and see how that goes."
Dirt Mile
Tapiture rebounded from a horrible run in the Cornhusker Handicap at Prairie Meadows to win Satuday's $100,000, Grade III Ack Ack Handicap at Churchill Downs by 1/2 length. It was a hard-won victory, after a long stretch battle with the favorite, Viva Majorca. Hat of Jacks was 4 lengths farther back in third. Tapiture, a 4-year-old Tapit colt, completed the one-turn mile over a fast track in 1:35.39 with Ricardo Santana Jr. up. He beat only one rival in the Iowa race and before that had missed the winner's circle in five straight races. "Nothing went well at Oaklawn with the weather early this year," said winning trainer Steve Asmussen. "I thought he hit a couple of tracks that were extremely laboring in his first races of the year. It got him a little flat, and then I thought the key to the race today was him getting away cleanly and not having to chase the spot."
Nyquist remained undefeated in four starts -- three of them stakes -- by winning Saturday's $300,000, Grade I FrontRunner Stakes at Santa Anita while negotiating two turns for the first time. The Uncle Mo colt, trained by Doug O'Neill for Paul Reddam, pressed the pace, took over in the lane and prevailed by 3/4 length over Swipe after two raced in close quarters late. Hollywood Don was a distant third. Mt Veder finished a fading sixth. Nyquist, with Mario Gutierrez aboard, ran 1 1/16 miles on a fast track in 1:44.89. Trainer Doug O'Neill said the race was tougher than he expected. "We were a little bit cocky before the race," he admitted. "But, at the end of the day, this is what we wanted to do. We wanted to win and we wanted to see if he'd two-turn in his own back yard ... Now with a two-turn win under his belt against the best 2-year-olds the West Coast has to offer, I think the plan will be for him to come out of it good and head back east in a few weeks, probably." The race was a "Win and You're In" for the Breeders' Cup Juvenile.
Full Salute stalked the pace in Saturday's $150,000 Hall of Fame Stakes at Parx Racing, moved by the leader when asked by jockey Paco Lopez and won under wraps, by 1 length over Bird of Trey. Discreet Lover and Formal Summation completed the order of finish. Full Salute, a Speightstown colt, ran 6 1/2 furlongs on a fast track in 1:17.43. He finished second in both the Tyro and the Sapling, both at Monmouth Park, before Saturday's effort.
Bring It On Dude went out to set the pace in Sunday's $75,000 Kip Deville Stakes at Remington Park and wasn't caught, winning by 2 lengths over the favorite, He's Comin' In Hot. Cale's Gold was third. Bring It On Dude, an Oklahoma-bred Munnings gelding, ran 6 furlongs on a fast track in 1:09.85 with Jareth Loveberry in the irons. He was making just his third start and recently broke his maiden, running against fellow Oklahoma-breds.
Sudden Surprise led from the start in Sunday's $150,000 Bertram Bongard Stakes for New York-bred 2-year-olds at Belmont Park and held off Get Jets at the end by a neck. Championofthenile finished third. Sudden Surprise, a Giant Surprise colt, ran 7 furlongs on a fast track in 1:23.52 with John Velazquez in the irons. Asked about his next race, winning trainer Todd Pletcher was optimistic. "I think today's race was an open stakes caliber race. There were some very good colts in here so I think everything is in play," Pletcher said.
Juvenile Turf
Isotherm rallied down the middle of the track in the closing yards of Saturday's $200,000, Grade III Pilgrim Stakes at Belmont Park and won by a neck over Azar and the same again over Ray's the Bar. The favorite, Eidmilaad, finished next-last of 10. Isotherm, sired by the Australian-bred Lonhro, ran 1 1/16 miles on the firm inner turf course in 1:41.98 under Jose Lezcano. It was his second win from three starts. "I kept telling everyone that he trains better than he ran last time," said winning owner Matthew Schera. "But he still won so we kind of expected something more today and it looks like he came out and he did it. We even think he likes the dirt too, so we'll see down the road for that. As long as he comes out good and he's healthy, we'll go to Keeneland for the Breeders' Cup Juvenile Turf."
Juvenile Fillies
Songbird ran her record to 3-for-3 with an easy win in Saturday's $300,000, Grade I Chandelier Stakes at Santa Anita. With Mike Smith up, the Medaglia d'Oro filly sped quickly to the lead and was never threatened, winning by 4 1/2 lengths, ridden out, in her first try around two turns. She earlier won the Grade I Del Mar Debutante going 7 furlongs and a 6-furlongs maiden race, also at Del Mar. Land Over Sea was a clear second in Saturday's race, 9 3/4 lengths ahead of Right There. Songbird ran 1 1/16 miles on the fast track in 1:43.79. Smith said Songbird "lived up to the expectations" and has an easy disposition to complement her talent. Dan Ward, assistant to winning trainer Jerry Hollendorfer, said the effort was "just what we wanted. She showed she can go two turns and now we've got five weeks" until the Breeders' Cup Juvenile Fillies. The Chandelier was a "Win and You're In" for that event.
Melodic took command in the lane in Sunday's $125,000 Joseph A. Gimma Stakes for New York-bred juvenile fillies at Belmont, winning off by 3 lengths from Frosty Margarita. The early leader, Surprise Cameo, finished third. Melodic, a daughter of Tale of the Cat, got 7 furlongs on a fast track in 1:25.01 with Kendrick Carmouche up.
Juvenile Fillies Turf
Tin Type Gal won a ding-dong stretch duel with Thrilled at the end of Sunday's $200,000, Grade III Miss Grillo Stakes at Belmont Park, scoring by a nose. Time and Motion was another 1 1/2 lengths back in third. Tin Type Gal, a Tapit filly, ran 1 1/16 miles on firm turf in 1:41.41 with Luis Saez aboard. It was her second win from three starts. "You have to think about the Breeders' Cup," said winning trainer Graham Motion. "That's why we're here. We're all pointing for those races."
Foundation showed in Saturday's Group 2 Juddmonte Royal Lodge Stakes for 2-year-olds at Newmarket that he has a good one -- foundation, that is. With Frankie Dettori up for trainer John Gosden, Foundation took over the lead with a furlong left in the 1-mile test, then was well enough in command to be geared down at the end. Deauville was kept to his task and finished second, 3/4 length back. Foundation, an Irish-bred Zoffany colt, got home in a pedestrian 1:38.04 over good turf. He now is 3-for-3 and the victory shaved a few quid off his odds for next year's Derby.
Dettori and Gosden also combined for a similar showing by Shalaa in the Group 1 Juddmonte Middle Park Stakes for 2-year-olds at 6 furlongs. The Invincible Spirit colt, winner of the Group 1 Prix Morny at Deauville in his last start, made all the going Saturday, was a clear winner and was not being asked for more as he finished 3/4 length ahead of runner-up Buratino. Steady Pace finished third. Shalaa was clocked in 1:11.92. He now has posted five straight victories after a career-opening loss. Dettori said he's never ridden a faster 2-year-old and Gosden said sprinting clearly will be Shalaa's forte. "He's not crying out for a mile," the trainer explained.
On the filly side of the juvenile ledger, Saturday's Group 1 Connolly's Red Mills Cheveley Park Stakes may have shed some light on things as pacesetter Lumiere held off Illuminate by 1/2 length under the wire. Beshara was a close third. Lumiere, a Shamardal filly, scored her second win. In the intervening time, she finished second to Beshara in the Group 2 Lowther Stakes at York. With William Buick up for trainer Mark Johnston, Lumiere ran 6 furlongs in 1:11.98. Johnston said the filly's determination raised hopes she can stay a mile and puts the 1,000 Guineas back in the picture.
Third Time Lucky came running late to win by a short head in Saturday's Betfred Cambridgeshire Handicap at Newmarket. Master the World was the hard-luck second, 2 lengths to the good of examiner. Thirty four runners faced the starter but Brendan Brackan unseated rider Colin Keane at the start, leaving 33 to cross the finish in the heritage handicap.
They seem to like things close in Australian Group 1 events. For the second straight time, a similar bunch produced a bunched-up finish in Saturday's Underwood Stakes at Caulfield although Mourinho produced an upset win, defeating the favorite, Fawkner, by a short head. The Cleaner was another nostril back in third with Mongolian Khan, Volkstok'n'barrell, Contributor, Hi World and Dandino in order behind, all within 3 lengths of the winner and all running well late. Mourinho, an 8-year-old Oratorio gelding, scored his second win of the season. He did not participate in the Makybe Diva Stakes, which found the first 12 finishers all within 2 1/2 lengths of Fawkner. The Cox Plate and the Caufield Cup beckon several of these -- not to mention the Melbourne Cup.
Richard Mandella
Jose Lezcano
Tyler Baze
Calvin Borel
Robby Albarado
Steve Margolis
Javier Castellano
Joe Bravo
Rafael Bejarano
Steve Asmussen
John Velazquez
Jerry Hollendorfer
Joe Hirsch
Lemon Drop Kid
Oklahoma Sooners win NCAA Cotton Bowl


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Latest pmbok 4th edition
By Mocage 07.10.2020 07.10.2020
The PMBOK® Guide is in need of an update. And PMI has made a lot of groundworks from in collecting feedback on the PMBOK® Guide 5th edition as well as noting the latest trends of project management. PMI has announced that the PMBOK® Guide 6 will be released at around the following schedule: 1st quarter of for draft release. The Fourth edition was published in The Fifth Edition was released in The latest English-language version of The PMBOK Guide — The Sixth Edition was released in September Purpose. The PMBOK Guide is intended to be a "subset of the project management body of knowledge that is generally recognized as a good practice Author: Project Management Institute. The PMBOK ® Guide and PMI global standards continually and accurately reflect the evolving profession. Extensions to the PMBOK ® Guide apply the guidance found in the PMBOK ® Guide to specific types of projects, meant to be used in conjunction with the PMBOK ® Guide. Go to the PMBOK ® Guide – Sixth Edition and Extensions to the PMBOK.
The PMBOK® Guide is in need of an update. And PMI has made a lot of groundworks from in collecting feedback on the PMBOK® Guide 5th edition as well as noting the latest trends of project management. PMI has announced that the PMBOK® Guide 6 will be released at around the following schedule: 1st quarter of for draft release. ORDER NOW. A Guide to the Project Management Body of Knowledge (PMBOK ® Guide) is PMI's flagship publication and is a fundamental resource for effective project management in any industry.. Over the past few years, more and more stakeholders have asked us for content on agile — and more are using agile practices, which is confirmed by our Pulse of the Profession ® research. The PMBOK ® Guide and PMI global standards continually and accurately reflect the evolving profession. Extensions to the PMBOK ® Guide apply the guidance found in the PMBOK ® Guide to specific types of projects, meant to be used in conjunction with the PMBOK ® Guide. Go to the PMBOK ® Guide – Sixth Edition and Extensions to the PMBOK. Apr 19, · PMBOK 6th Edition PDF Download for PMP Certification: PMBOK Guide Sixth Ed (PDF) is available for download FREE of cost for PMI Members. What's New in PMBOK Guide, 6th Edition - A Summary of Changes. 11 minute read. If you have the PMI ID, why don't you use the link (given in the post above) and download the PMBOK Guide 4th Edition. Apr 25, · The PMBOK Guide 5th Edition was launched on December 31, , four years after publishing the 4th Edition. This is a major update, and many things have changed in the latest edition . 41 Changes to the Exams PMBOK 5th Edition Those taking the Certified Associate in Project Management (CAPM®) Exam • Before July 1, – Use the PMBOK 4th Edition • After July 1, – Use the PMBOK 5th Edition Thos taking the Project Management Professional. Jan 11, · PMBOK, 4th edition revisited Earlier this year, I had reported that the new version of the Project Management Body of Knowledge, the fourth edition, PMBOK 5th Edition [UPDATE April 28th, There are more than new terms in the 5th edition of the PMBOK, and we All new terms of the PMBOK 5th edition It took a bit longer to go through. The Fourth edition was published in The Fifth Edition was released in The latest English-language version of The PMBOK Guide — The Sixth Edition was released in September Purpose. The PMBOK Guide is intended to be a "subset of the project management body of knowledge that is generally recognized as a good practice Author: Project Management Institute. Download PMBOK Guide 4th Edition - PMP Certification Exams Preparation based on PMI's 4th Edition of PMBOK Guide, Global Standard for Project Management. Learn about Project Management Rules of Seven Project Crashing Fast Tracking Project Quality Planning Project Execution Just-In-Time Analogous Estimation PERT CMP Activity on Array AOA AON Centralized Contracting PMI .The PMI has released the 4th edition of the Project Management version of the Project Management Body of Knowledge, the fourth edition. On 1 August PMP® exam moves over to using PMBOK® 5th edition. As with any new thing, you might be feeling bit jittery about PMBOK 5th edition. Simply make a copy of the relevant page of the PMBOK® Guide, mark the error . A Guide to the Project Management Body of Knowledge (PMBOK® Guide) Edition .. a national monument will create a result expected to last centuries. MANAGEMENT BODY OF KNOWLEDGE. (PMBOK® Guide) – Fifth Edition. Licensed To: Jorge Diego Fuentes Sanchez PMI MemberID. The changes to the PMBOK Guide 4th edition are mainly in the area of readability , linkages to other PMI standards, and clarifying how the project documents. The PMBOK® Guide–Fourth Edition continues the tradition of excellence in project management with a standard that is even easier to understand and. Robert Sedgewick and Kevin Wayne - Algorithms, 4th solidarityiran.info Project Management Professional (PMP®) Exam PMBOK® Guide Fourth Edition. R. Carter. ANSI/PMI Project Management Institute. A GUIDE TO THE PROJECT. MANAGEMENT BODY OF KNOWLEDGE. (PMBOK® Guide)—Fourth . A Guide to the Project Management Body of Knowledge 4th Edition. by .. So, go ahead and buy another book on studying for the PMP exam, but if that book . I bought this version (rather than the current 6th-edition) because of the myriad. Now in its fourth edition, The Standard for Portfolio Management reflects current practices and has been updated to reflect the evolution of the profession. 8 ball pool by miniclip apk, ip tool canon centre, mon majhi re boss ringtone
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For people who are impatient or always on the go. These people are continually rushing and their lives are always overflowing with commitments. This remedy enables these people to slow down, to reach that still centre in themselves, and find calmness and inner guidance.


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Red Giant's New Effects Library and Community – Universe
in Editors, Filmmaking, Post-Production
Visual effects software developer Red Giant today announced the public beta of Red Giant Universe, a new environment for building as well as distributing filter and transition effects. The effects and transitions are GPU-accelerated, work on both Mac and Windows, and support After Effects, Premiere Pro, Final Cut Pro X and Motion.
Red Giant says they are releasing 50 new free and premium tools as part of Universe, but prior to release did not specify how many of them are free. Universe's Premium option provides access to more tools as well as existing Red Giant tools that will be ported to Universe, including Knoll Light Factory EZ, Holomatrix, Retrograde, and ToonIt. Taking a leaf from Adobe's book, Red Giant is offering subscriptions of $10 a month, and $99 yearly, but they are also offering a $399 lifetime subscription.
Also taking a leaf from Adobe's Cloud, Red Giant says that there will be frequent updates throughout the year.
A demo video shows a tool called Supernova, which seems to be an easy way to build new effects based on the basic effects in Universe. It's unclear from the video whether Supernova will be available to members of Universe, or whether it's only an internal tool for Red Giant's use.
Supernova environment
I haven't been able to try the beta yet, but I did get to watch two explanatory videos which look intriguing but also left many questions unanswered. What's included? Can end-users build effects? What is the community aspect of this? The only community feature mentioned are that members will be able to help choose effects and transitions Red Giant builds, and Premium members will get early betas of new products.
The public beta should answer most of those questions today, so you might want to take advantage of it now; Red Giant's public betas usually last only a month or so.
http://redgiant.com/universe
"He'd Kill You If He Got the Chance…": Editor Walter Murch on Coppola's The Conversation, the Nodal Concept of Montage and Our Modern Surveillance State by Evan Louison in Editors, Interviews
"Ultimately, the Solution Isn't There Until the Pressure Has Been Lifted": Youngstown Director Pete Ohs on Microbudget Filmmaking and the Benefit of Being One's Own Crew by Taylor Hess in Cinematographers, Directors, Editors, Interviews, Producers, Screenwriters
"I Find that God is in the Mistakes, I'm Finding Moments Where the Actors Don't Know the Camera's on Them": Hank Corwin on Editing Don't Look Up by Daniel Eagan in Editors, Interviews
Trailer Watch: Django Unchained By Scott Macaulay on Oct 10, 2012
25 Picks for the 2013 Tribeca Film Festival By Scott Macaulay on Apr 18, 2013
The Power of Story: Previewing the 2015 Tribeca Film Festival By Scott Macaulay on Apr 16, 2015
A Look at the New Blackmagic Design Cameras By Jamie Stuart on Aug 9, 2013


Blue is a 2002 Japanese romantic drama directed by Hiroshi Ando based on the manga of the same name by Kiriko Nananan. Blue is about Kayako Kirishima's a schoolgirl who always feel alone and uneasiness about her future Until a day She make friend with Endo, a same classmate. Kayako is strongly appealed to Endo.


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Select a Country or Region
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What is SMA?
What causes SMA?
Types of SMA
How is SMA Inherited?
Diagnosis and Testing
SMA in Infants & Children
SMA in Adults
How to get diagnosed
SMA Care for Adults
Disease Stabilisation
SIGNS AND
Every child with spinal muscular atrophy (SMA) is affected differently. Age of onset, symptoms, characteristics of SMA and disease severity differ greatly from one child to the next.1
The characters shown are real patients and the required consent to use their stories has been obtained from the patients and families. Photographs are for illustrative purposes only.
SPINAL MUSCULAR ATROPHY IN INFANTS & CHILDREN
SMA is a rare, genetic neuromuscular disease1,2 and a leading genetic cause of infant and toddler mortality.3
Children may experience progressive muscle weakness in the muscles closest to the centre of the body, such as the shoulders, thighs, and pelvis. These muscles enable activities such as crawling, walking, sitting up, and controlling head movement. Their ability to breathe and swallow may also be affected.4
SMA does not affect the neurons responsible for cognition, which is the mental process through which we gain knowledge and understanding through thought, experience, and the senses.5.6
According to one study, children and adolescents with SMA have normal intelligence, with IQs in the standard range.7
SMA AFFECTS EVERY CHILD DIFFERENTLY
Symptoms may include progressive muscle weakness, floppiness, and muscle wasting (atrophy). Muscle weakness is usually the same on both sides of the body.9
Each child may experience symptoms differently, and the disease is divided into types based on age of onset and functional ability. There is also a range of severity within each type, and as many as 25% of individuals may not have a precise type.10
MISSING CERTAIN MILESTONES MAY BE THE FIRST SIGN OF SMA
Spinal muscular atrophy is often first suspected by a parent who may notice that their child is not meeting certain milestones. Parents may observe that their child is not reaching typical physical milestones for their age, such as the ability to hold their head up, to roll over, or to sit up independently.
Swallowing or feeding may also become difficult, and children may lose the ability to swallow safely without choking or inhaling food into the lungs (aspiration).5,11
While all babies develop at their own pace, the World Health Organization (WHO) offers general motor milestone guidelines as part of the Multicentre Growth Reference Study (MGRS).12
Adapted from WHO Multicentre Growth Reference Study Group, 200613
MOTOR MILESTONE GUIDELINES12
GROSS MOTOR MILESTONE PERFORMANCE CRITERIA
1.Sitting without support
Child sits up straight with head erect for ≥ 10 seconds.
Does not use arms or hands to balance body or support position.
2.Crawling on hands and knees
Child moves forward or backward on hands and knees.
The stomach does not touch the supporting surface.
Continuous and consecutive movements, ≥ 3 in a row.
3.Standing with assistance
Child stands in upright position on both feet, holding on to a stable object, such as furniture.
Child stands holding on for ≥ 10 seconds.
4.Walking with assistance
Child is in upright position with back straight.
Makes sideways or forward steps holding on to stable object with one or both hands.
One leg moves forward while the other supports body weight.
Child takes ≥ 5 steps.
5.Standing alone
Child stands in upright position on both feet (but not on the toes) with the back straight.
The legs support 100% of the weight, without holding on, for ≥ 10 seconds.
6.Walking alone
Child takes ≥ 5 steps independently, with the back straight.
One leg moves while the other supports most of the weight.
There is no contact with a person or object.
CHARACTERISTICS OF SMA IN INFANTS AND CHILDREN
Find out more about the characteristics and different types of SMA at various ages of onset:
( INFANT-ONSET )
( INTERMEDIATE )
( JUVENILE-ONSET )
(ADULT-ONSET )
Late adolescence / adulthood
DEVELOPMENTAL MILESTONES:11
Can hold head up and begins to push up when lying on stomach; makes smoother movements with arms and legs.
Holds head steady, unsupported; pushes down on legs when feet are on a hard surface; may be able to roll over from stomach to back; can hold a toy and swing it at dangling toys; brings hands to mouth; when lying on stomach, pushes up to elbows.
Rolls over in both directions (front to back and back to front); begins to sit without support; when standing, supports weight on legs and might bounce; rocks back and forth, sometimes crawling backwards before going forward.
Highest motor milestone achieved
Unable to sit ("non-sitters")
≤ 2 years14
SMA Type
Type 1 (also known as Werdnig-Hoffmann disease)
Characteristics:14,17,18
Poor head control
Weak cough
Weak cry
Progressive weakness of muscles used to chew and swallow
"Frog-leg" posture when lying
Severe muscle weakness on both sides of body
Progressive weakness of muscles that help in breathing (intercostal muscles), resulting in the characteristic "bell-shaped" chest
Stands, holding on; can get into a sitting position; sits without support; pulls to stand; crawls.
1 year:
Gets into sitting position without help; pulls up to stand, walks holding onto furniture (cruising); may take a few steps without holding on; may stand alone.
Able to sit independently ("sitters")
> 2 years14
70% still living at age 25
Type 2 (also known as Dubowitz disease)
Characteristics:17, 18
Swallowing, coughing, and breathing problems may occur but are typically less common
Muscle aching and joint stiffness symptoms
Children may develop spinal problems such as scoliosis (curvature of the pine), which may require bracing or surgery
Able to walk independently ("walkers" - although they may progressively lose this ability)
Normal14
Type 3 (also known as Kugelberg-Welander disease)
Chewing and swallowing difficulty
Muscles in the legs are generally more severely affected than the arms
Muscle aching
Joint overuse symptoms
Physical symptoms are similar to juvenile-onset spinal muscular atrophy, with the gradual onset of weakness, tremors, and muscle twitching first noted in late teens or early adulthood
Parents' reports of their children's gross motor development tend to be reliable. Sharing observations of potential motor delays with a doctor can help determine an appropriate care strategy.19,20
1. Wang CH, et al. Consensus statement for standard of care in spinal muscular atrophy. J Child Neurol. 2007;22(8):1027-1049.
2. Genetics Home Reference. SMN2 gene. 2012. Available at: https://ghr.nlm.nih.gov/gene/SMN2. Accessed January 9, 2017.
3. Lunn MR, Wang CH. Spinal muscular atrophy. Lancet. 2008;371(9630):2120-2133.
4. Finkel R, et al. 209th ENMC International Workshop: Outcome Measures and Clinical Trial Readiness in Spinal Muscular Atrophy 7-9. November 2014, Heemskerk, The Netherlands. Neuromuscul Disord. 2015;25(7):593-602.
5. Qian Y., McGraw S., Henne J., Jarecki J., Hobby K., Yeh W.S. Understanding the experiences and needs of individuals with Spinal Muscular Atrophy and their parents: A qualitative study. BMC Neurol. 2015;15:1–12. doi: 10.1186/s12883-015-0473-3.
6. National Organization for Rare Disorders. Werdnig-Hoffman Disease. 2012. Available at: https://rarediseases.org/rare-diseases/werdnig-hoffmann-disease/. Accessed January 9, 2017.
7. Von Gontard et al. Intelligence and cognitive function in children and adolescents with spinal muscular atrophy. Neuromuscul Disord. 2002. Feb;12(2):130-6.
9. D'Amico A, et al. Spinal muscular atrophy. Orphanet J Rare Dis. 2011;6:71.
10. Kolb SJ, Kissel JT. Spinal muscular atrophy. Arch Neurol. 2011;68(8):979-984.
11. Centers for Disease Control and Prevention. Developmental milestones. Available at: http://www.cdc.gov/ncbddd/actearly/milestones/. Updated January 21, 2016. Accessed April 27, 2016.
12. Wijnhoven TMA, de Onis M, Onyango AE, et al; for the WHO Multicentre Growth Reference Study Group. Assessment of gross motor development in the WHO Multricentre Growth Reference Study. Food Nutr Bull. 2004;25(1 suppl 1):S37-S45.
13. WHO Multicentre Growth Reference Study Group. Acta Paediatr Suppl. 2006;450:86-95. Available from: https://pubmed.ncbi.nlm.nih.gov/16817682/.
14. Markowitz JA, Singh P, Darras BT. Spinal muscular atrophy: a clinical and research update. Pediatr Neurol. 2012;46(1):1-12.
15. Haaker G, Fujak A. Proximal spinal muscular atrophy: current orthopedic perspective. Appl Clin Genet 2013;6:113-120.
16. Darras BT. Spinal muscular atrophies. Paediatr Clin North Am 2015;62(3):743-766. DOI: 10.1016/j.pcl.2015.03.010.
17. Mercuri E, et al. Diagnosis and management of spinal muscular atrophy: Part 1: Recommendations for diagnosis, rehabilitation, orthopedic and nutritional care. Neuromuscl Disord. 2018;28(2):103-115.
18. Prior TW, Russman BS. Spinal muscular atrophy. NCBI Bookshelf Website. Available at: http://www.ncbi.nlm.nih.gov/books/NBK1352/. Updated November 14, 2013. Accessed April 15, 2016.
19. Noritz GH, Murphy NA; and Neuromuscular Screening Expert Panel. Motor delays: early identification and evaluation. Pediatrics. 2013;131(6):e2016-e2027.
20. Lawton S, Hickerton C, Archibald AD, McClaren BJ, Metcalfe SA. A mixed methods exploration of families' experiences of the diagnosis of childhood spinal muscular atrophy. Eur J Hum Genet. 2015;23(5):575-580.
What causes SMA
How is SMA inherited
Diseases with Similar Symptoms
SMA COMMUNITY
Adults Living with SMA
©2021 Biogen. All rights reserved.
This site is intended for Gulf residents aged 18 and older.
Job code: Biogen-87800.
Date of preparation: August 2021.


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Thomas Andrews Hendricks (Fultonham, Ohio, 7 de septiembre de 1819-Indianápolis, Indiana, 25 de noviembre de 1885) fue un político estadounidense, Representante, Senador por Indiana, Gobernador de Indiana, y  vicepresidente de Estados Unidos.

Hendricks fue un político muy popular dentro del Partido Demócrata, ya que fue el primer miembro de aquel partido en ganar una elección en un estado del norte tras la Guerra de Secesión. Por otra parte, durante aquel conflicto, se encontraba desempeñándose como senador y no vaciló en su posición. Su mandato como de Indiana se vio sacudido por el pánico de 1873. No tuvo mayoría legislativa demócrata en la legislatura local, por lo que tampoco destacó en la creación de leyes significativas.

Fue candidato a vicepresidente acompañando a Samuel J. Tilden, en las controvertidas elecciones de elecciones presidenciales de 1876, sin resultar la fórmula electa. Sin embargo, en la elección de 1884, y pese a encontrarse en un precario estado de salud, fue escogido como compañero de fórmula de Grover Cleveland. Fue elegido, pero falleció ocho meses después de asumir el cargo.

Referencias

Políticos de Indiana
Personas de Ohio
Vicepresidentes de Estados Unidos
Graduados honorarios de la Universidad de Indiana
Demócratas de Indiana
Fallecidos en Indianápolis
Senadores de Estados Unidos por Indiana
Miembros de la Cámara de Representantes de Estados Unidos por Indiana

redpajama_set_name: RedPajamaWikipedia


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Three Irish Named All-Americans
Notre Dame Athletics | April 2, 2020
NOTRE DAME, Ind. — The Notre Dame men's lacrosse program had three players from the 2020 squad selected by Inside Lacrosse as All-Americans following the shortened season. Bryan Costabile received second team honors, Jack Kielty was bestowed third team status and Arden Cohen was named an honorable mention.
All three players also appeared on the Inside Lacrosse Preseason All-America lists.
Costabile was tied for the team lead in goals through five games with 10, while also adding five assists. The senior ranks second on the Notre Dame career goal scorer chart for a midfielder with 99. Costabile is an Inside Lacrosse three-time All-American.
Kielty was the leader of the Irish defense in 2020 after starting each of the last three years. The defenseman caused five turnovers and scooped up 12 ground balls over five games. Over four years Kielty has played in 50 games and has scooped up 104 ground balls.


PASADENA, CA. – The Pomona-Pitzer Men's Soccer Team came through with a clinical 2-0 victory over Caltech in their Southern California Intercollegiate Athletic Conference opener on Wednesday evening thanks to goals from Matthew Carlson and Peter Heckendorn. The Sagehens dominated possession, outshooting the Beavers 21 to 9 and goalkeeper Bryan Diangson collected six saves for his shutout.
Season Impact: The Sagehens improve to a 2-1 record overall and collected their first win in SCIAC play. The Beavers are 1-1 overall and 0-1 in the SCIAC.
Pomona-Pitzer looked to find the opening goal in the 21st minute when Bjorn Sigurdsson found Jared Mejia on a corner kick. Mejia leapt for the header, but saw his attempt saved by Caltech's goalie Joe Como. Eamon Stein tried a shot in the 33rd minute for the Hens, but his attempt was stopped by Como as well.
After a scoreless first half, the Sagehens pounced early after halftime when Jared Mejia found Carlson for the opening goal just two and a half minutes into the second half.
Later in the 66th minute, Taylor Reifort delivered a cross to Heckendorn on a corner kick and Heckendorn connected in the box to double the lead.
Panic ensued in the 87th minute when the Sagehens committed a foul in their own box, giving the Beavers a chance to cut the lead in half. Kevin Yu of Caltech took the penalty shot, but saw his attempt saved by Diangson as the Sagehens preserved the shutout.
Up Next: The Sagehens will next host Macalester on Sunday, September 9 at 11:00 a.m.


text:
<?php

namespace App;

use App\Traits\GetsGeo;
use App\Traits\NotNullOrEmpty;
use Illuminate\Notifications\Notifiable;
use Illuminate\Foundation\Auth\User as Authenticatable;

/**
 * App\User
 *
 * @property int $id
 * @property string $name
 * @property string $email
 * @property string $password
 * @property string $remember_token
 * @property \Carbon\Carbon $created_at
 * @property \Carbon\Carbon $updated_at
 * @property string $deleted_at
 * @property string $honorific_prefix
 * @property string $given_name
 * @property string $additional_name
 * @property string $family_name
 * @property string $sort_string
 * @property string $honorific_suffix
 * @property string $nickname
 * @property string $logo
 * @property string $photo
 * @property string $url
 * @property string $uid
 * @property string $category
 * @property string $tel
 * @property string $note
 * @property string $bday
 * @property string $key
 * @property string $org
 * @property string $job_title
 * @property string $role
 * @property string $impp
 * @property string $sex
 * @property string $gender_identity
 * @property string $anniversary
 * @property string $organization_name
 * @property string $organization_unit
 * @property string $tz
 * @property string $rev
 * @property string $post_office_box
 * @property string $extended_address
 * @property string $street_address
 * @property string $locality
 * @property string $region
 * @property string $postal_code
 * @property string $country_name
 * @property string $label
 * @property string $latitude
 * @property string $longitude
 * @property string $altitude
 * @property-read array $adr
 * @property-read \Illuminate\Notifications\DatabaseNotificationCollection|\Illuminate\Notifications\DatabaseNotification[] $notifications
 * @property-read \Illuminate\Notifications\DatabaseNotificationCollection|\Illuminate\Notifications\DatabaseNotification[] $readNotifications
 * @property-read \Illuminate\Notifications\DatabaseNotificationCollection|\Illuminate\Notifications\DatabaseNotification[] $unreadNotifications
 * @method static \Illuminate\Database\Query\Builder|\App\User whereId($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereName($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereEmail($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User wherePassword($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereRememberToken($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereCreatedAt($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereUpdatedAt($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereDeletedAt($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereHonorificPrefix($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereGivenName($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereAdditionalName($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereFamilyName($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereSortString($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereHonorificSuffix($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereNickname($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereLogo($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User wherePhoto($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereUrl($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereUid($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereCategory($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereTel($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereNote($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereBday($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereKey($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereOrg($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereJobTitle($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereRole($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereImpp($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereSex($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereGenderIdentity($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereAnniversary($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereOrganizationName($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereOrganizationUnit($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereTz($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereRev($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User wherePostOfficeBox($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereExtendedAddress($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereStreetAddress($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereLocality($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereRegion($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User wherePostalCode($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereCountryName($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereLabel($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereLatitude($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereLongitude($value)
 * @method static \Illuminate\Database\Query\Builder|\App\User whereAltitude($value)
 * @mixin \Eloquent
 */
class User extends Authenticatable
{
    use GetsGeo, Notifiable, NotNullOrEmpty;

    /**
     * The accessors to append to the model's array form.
     *
     * @var string[]
     */
    protected $appends = ['adr'];

    /**
     * The attributes that are mass assignable.
     *
     * @var array
     */
    protected $fillable = [
        'name', 'email', 'password',
    ];

    /**
     * The attributes that should be hidden for arrays.
     *
     * @var array
     */
    protected $hidden = [
        'altitude',
        'country_name',
        'created_at',
        'extended_address',
        'id',
        'label',
        'latitude',
        'locality',
        'longitude',
        'password',
        'postal_code',
        'post_office_box',
        'region',
        'remember_token',
        'street_address',
        'updated_at'
    ];

    /**
     * Get the adr for the card for serialization.
     *
     * @return array
     */
    public function getAdrAttribute()
    {
        $adr        = [];
        $properties = [
            'country_name',
            'extended_address',
            'label',
            'locality',
            'postal_code',
            'post_office_box',
            'region',
            'street_address'
        ];

        $adr['geo'] = $this->getGeo();

        foreach ($properties as $property) {
            $adr[$property] = $this->attributes[$property];
        }

        return static::filterNotNullOrEmpty($adr);
    }

    /**
     * Convert the model instance to an array.
     *
     * @return array
     */
    public function toArray()
    {
        $attributes = parent::toArray();
        $attributes = static::filterNotNullOrEmpty($attributes);

        // Remove the user->adr->geo key if it's an empty array.
        if (!$attributes['adr']['geo']) {
            unset($attributes['adr']['geo']);
        }

        // Remove the user->adr key if it's an empty array.
        if (!$attributes['adr']) {
            unset($attributes['adr']);
        }

        return $attributes;
    }
}


The tour begins from the Venetian lion-guarded port of Heraklion with a drive through the city to the famous wine producing area of Peza, south of Heraklion. The drive is through breathtaking landscape of countryside and vineyards as old as Minoan times. The first stop is a modern winery, where you will see the updated methods of wine making and sample some of the delicious Cretan wines. The drive continues through rural villages to the village of Archanes, the municipality in the area. On the way, a photo stop is made at Vathypetro to view one of the oldest farmhouses in Crete, dating to the Minoan period 16th century B.C.. The tour continues through the island's hilly countryside where olive groves and vineyards existed from as far back as 4.000 years. Arriving at the village of Archanes, which is situated 10km south of the Palace of Knossos, the quaint market town of Archanes has many restored sandstone houses dating from the Turkish period. At a tavern in the villages' tree-shaded square, you can sample an assortment of Cretan snacks and locally produced wine, and have a chance to mingle with many of the locals themselves while listening to typical Greek live music. You will have free time to browse before the return drive to the port of Heraklion and the ship.


text:
How the age of misinformation and partisanship has influenced COVID-19 era | Opinion
Are we reaching a turning point in the history of fake news? Probably not, but maybe we're in for a short respite.
Joe Hayden | Guest Columnist
New Fourth Bluff Park installation looks to inspire peace
The Memphis Peace Project also wants to offer in-person programming and discussions that could help lead to community healing.
Joe Hayden, a professor of journalism at the University of Memphis, is writing a history of fake news in America.
Welcome to Alice in Wonderland, where up is down and night is day, where contradictions ooze from the same mouth, just a few weeks later. That's been our media world in recent decades, and especially the last few years, but something has quietly changed in 2020.
Like the simultaneous occurrence of two natural disasters, fake news and the coronavirus were bound to collide at some point, but their clash hasn't been a battle of equals. Despite the distortions and cover-ups about the virus, Mother Nature has prevailed, often brutally.
Disinformation, the deliberate distortion of facts, has always existed, but in this age of social media, instant publicity, and partisan fakery, it spreads exponentially.
Amplification and virality have transformed our mass media into institutions very different from just a generation ago. It's not that the media gatekeepers are gone; it's that their power has decentralized as their numbers have soared. What remains, however, isn't anarchy so much as masquerade. What you see is not necessarily what you get.
Into the world came COVID-19
Although some of the usual purveyors of falsehood have seized on the phenomenon to peddle conspiracies, the pandemic has also confronted them with a lethal, all-encompassing force that ruthlessly challenges the lies. In short, it's hard to remain a virus-denier for long, as even the president has discovered.
The "Patient Zero" in political prevarication—President Donald Trump—went from scoffing at the virus to downplaying it to shrugging at it to warning about it to contracting it to possibly losing reelection because of it.
He's held more positions on it than just about anybody and struck more poses than a teen on prom night. But whereas the president never stopped flailing at the Mueller report as a "witch hunt," he has apparently come around to accepting the authenticity of this crisis.
That hasn't, of course, meant that he has led effectively, or at all. Nor does it mean he's still not downplaying it or undermining an effective response to it. It does suggest that what the so-called "adults in the room"—people like former advisers John Kelley, Rex Tillerson, and Jim Mattis—couldn't accomplish, the coronavirus has.
It's somewhat dampened Trump's compulsion for incessant salesmanship and thwarted his attempt to promote an alternative reality. Although we saw him staging photo ops after his departure from Walter Reed Hospital, we also watched him gasping for air at the top of the White House steps and hear from his doctors that he was taking Remdesivir, Regeneron, and Dexamethasone, a powerful rebuttal to anyone that the virus isn't real or dangerous, even for this most protected of American citizens.
Hear more Tennessee Voices: Get the weekly opinion newsletter for insightful and thought provoking columns.
The president still strives daily to push a competing national narrative. But the contagion isn't bending to his will; he's been forced to bow to its. In fact, it's one of the reasons that a majority of Americans, an unprecedented 78 million-plus voters, decided to fire him last week.
You saw that defeatism in his press briefings throughout the year, where he was cowed by the moment and intimidated by the science of it all, and then last month when he was finally medevaced to a hospital because of it.
Trump's media allies have also squirmed
A study of Fox News broadcasts this spring shows their hosts lurching from one contradictory viewpoint to another. First they accused Democrats of "coronavirus hysteria" on Feb. 28.
A month later, on March 31, they were blaming the impeachment process for distracting the president, nearly conceding the contention of critics that he faltered when more action might have made a difference. They pushed back about whether Trump ever called the pandemic a "hoax," then acknowledged it by grumbling over whether he should have used that word and "coronavirus" in the same sentence at a rally in South Carolina.
In the process, then, right-wing pundits and their viewers have had to reconsider their troubled relationship with journalism, science and the federal government. Fringe conspiracists have at times been forced to take a back seat to actual health officials.
The fact that for a time the president was forced to share a stage or air time with Dr. Anthony Fauci and Dr. Deborah Birx shows that the power dynamic in Washington shifted.
While the market struggles to recover, the federal government looms as the only force capable of mounting a recovery. America's agenda has been commandeered. For most of this year, we weren't paying attention to sports, entertainment, or even the stock market. We've been too focused on immunology.
That's because in times of great duress, citizens crave information more than ideology. That's been true during war, and it appears to be the case now. When it comes to life and death, the facts of survival eventually outpace the spin of politics.
As former President Barack Obama put it in a video he released in April, "pandemics have a way of cutting through a lot of noise and spin to remind us of what is real and what is important."
As for the lies and deception, they haven't gone away. But their influence for the moment seems muffled and meek.
That's not likely to last.
It is a reason to feel relief—and maybe a little hope.