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redpajama_set_name: RedPajamaGithub


Bond Vs Stock Market – Which Is The Best Investment Option? | Everything You Wanted To Know About Accounting, Finance, Money & Tax!
Bond Vs Stock Market – Which Is The Best Investment Option?
Among the prominent financial centers of trade, the names of bond and stock market are quite evident. The key role of such centers is to help in raising fund. They are utilized by the businesses and the governments too. When we talk about the bond market, the key aspect of this market is that in this market, government participates more and as far as stock market is concerned, the investors and the companies that are needed to sell their equities participate fully.
Bond market is actually known as a debt market too and when a company feels the need of loan then it issues its bond that is bought by the interested investors. Actually in this way, investors provide loan to the companies and in return they get a bond that holds date of maturity and the interest rate. The benefit behind such investment is that the investors do not only get the principal amount but the interest too. The investors possess the right to sell these bonds to other people too once they have purchased from the company. Stock market is also regarded as the share market. The stock market has some resemblance with the bond market but it is different too in some aspects. In this market, the investors do not provide loan to the companies. Actually, they have to purchase the company's equity that will depreciate or appreciate in value with the working conditions of the company. Such people or investors who hold the share of the company are being paid the dividends if the company is desperate to share the profits. The value of stock can increase too with the span of time. There are some key points that help us in truly identifying the basic differences between bond and stock market.
It is considered that the bond market is more secure and safe when it is compared with the stock market because the bond market does not get affected with the reactions of the investors as we see in the case of stock market. The second thing is that the bond is surer than the stock. Particularly when we talk about the government bonds, they are considered the most advantageous and solvent form of investment.
The bond holders have no right to influence the decisions that are taken by the company where as the stock holders can influence the company's decisions because they possess the share and they have right to exercise their ownership.
Stock market is more liquid than the bond market because shares are traded easily whereas the bonds cannot. Speculation is a major part of a stock market and it is done to make the profit possible whereas in bond market it is very hard to some extent. So profit ratio is high in stock market when it is compared with the bond market.
In short, these are some points that truly help us in differentiating between stock market and the bond market in wider terms.
Monetary Unit – What is stable monetary unit concept?


After garnering the attention of renowned artists such as Masta Ace, Wordsworth and Kool G Rap, and collaborating with each respectively, New York native Pearl Gates is leveling up once again with the release of his debut album, Live From The First.
For the Washington Heights emcee's latest, he artfully chooses to chronicle his transition from the streets to the studio, with the rapper recruiting the likes of Torae, Cassidy, Camp Lo's Geechi Suede and a handful of up-and-coming artists as featured guests on his new project.
Spanning 17 tracks, the ambitious full-length is full of stories from his block on 181st street in upper Manhattan, with Pearl Gates waxing poetic over how far he's come and where his music will be taking him next, God-willing.
"Most of the tracks on the album revolve around stories and experiences from the block" he shared, speaking on the album. "I'm talking on past experiences I had, however, I'm using the drug game as a metaphor for taking over the rap game."
Take a listen to Pearl Gates' new album Life From The First, courtesy Below System Records, below and cop via iTunes.


Brandi Raae: Should Christians Use the Word Easter?
It's possible that the word, Easter, originates from a Germanic goddess of the dawn named Eostre. Different sources include variations of the spelling such as Estre, Estara, Ester, Ostara, and more.
Alexander Hislop, a Free Church of Scotland minister, says that Eostre is derived from a Babylonian goddess, Astarte. Which may even be connected to other pagan goddesses such as Ishtar, the Mesopotamian East Semitic goddess; Ashtoreth, the Phoenician goddess; etc.
If these claims are true, does it even matter? Well, in this particular case, I don't think it really does.
What Does Easter Mean Today?
Ever since I stopped believing in the Easter bunny, I've always associated the word Easter with Jesus and his triumph over death. I've never once thought about pagan goddesses and their unholy festivals. Have you?
I also found a neat blog post by Kevin Haah concerning the German word, Oster. He says Martin Luther chose to use the word Oster to refer to the Passover (Pascha) when translating the New Testament into German in 1522. Haah also states that Oster is an old German word for resurrection.
There's a whole lot more to all of these words (Oster, Pascha, etc.) and their derivations. I'm no scholar, and so many others have already tackled the subject quite sufficiently. Plus, all of these unfamiliar words start to rattle around like pebbles in my brain making me a tad bit crazy! My take is that it is totally and appropriately fine to refer to the resurrection celebration of the perfect Passover Lamb as Easter.
Pondering the word, Easter, and its origin got me to thinking about other words we use that really can be traced back to pagan roots. When you thank God for a beautiful Sunday or wish it was Friday already, do you even think about the origin of these days of the week? All the days of the week originate from the names of pagan gods, but we don't think twice about saying those.
What about the planets? All except Earth are named for Roman/Greek gods. I bet it's safe to say that we just think of the names of days and planets as the names of days and planets. Maybe one day we'll find out the real names God has given to the planets and stars and days and everything else that stems from pagan origin, but for now Mars is the 4th planet from the sun and Saturday is the 7th day of the week. Is it wrong for us to call these everyday words by their pagan names?
If I told my son that he wrote a "terrific" paper, I'm sure he'd take it to mean that I thought it was great. And rightly so. But it originally meant terror-inducing.
If I referred to the kid down the street as a "bully", you'd probably think he or she was someone who picked on other kids. But, in the old days it was used as a term of endearment to mean sweetheart or good friend.
And the list goes on and on. My point, here, is that even if Easter originated from the name of an ancient pagan goddess, it doesn't have the same meaning today. Christians who use the word, Easter, aren't' associating it with paganism.
So, this Sunday whether you wish someone a "Happy Easter!" or a "Happy Resurrection Day!" let us be like-minded, having the same love and being one in spirit and of one mind all for the sake of Christ.
Let us not get bogged down by origins and ancient meanings. Let us focus on the WHO not the whats.
For Christ has conquered sin and death and has rescued us from the penalty of sin, is rescuing us from the power of sin, and will one day rescue us from the presence of sin.
P.S. HAPPY EASTER! This post may be linked to one or more of these fabulous link-ups.


Bernadette Hardaker is an Orangeville freelance writer who specializes in memoir writing.
To a 13-year-old Orangeville boy in September 1945, news that the father he hadn't seen in four years was on his way home from the battlefields of Europe was cause for high excitement.
The friendship among graduates of the old 'school on the hill' has stood the test of time.
In Sketching Sunshine, actor and playwright Joe Matheson delves deep into the complex character of Canada's iconic humorist.
Children were expected to work, often in the cruellest of conditions. Destitute, abandoned or orphaned, many children survived by their wits on the street.


text:
representation in the sciences
underrepresented minorities in the science
Ethics of Memory Research: The Scientist and Society with Dr. Ashleigh Maxcey
By Erin Morrow
This post is the first in a series featuring interviews that will explore ethical issues surrounding research in memory science. Each interview will highlight a specific theme on this topic with the insights of a research professor in psychology or brain science. The series will consist of five interviews over the span of a year.
Image courtesy of PxHere/Mohamed Hassan
In late May, I sat down virtually with Dr. Ashleigh Maxcey, Senior Lecturer and Research Assistant Professor of Psychology at Vanderbilt University. In her research, Maxcey investigates the cognitive mechanisms that underlie forgetting, particularly a phenomenon known as induced forgetting in which the researcher can impair an individual's memory for certain items through the act of retrieving others. In addition to this work, Maxcey is Chair of the Psychology Department Equity, Diversity, and Inclusion Committee at Vanderbilt and co-hosts the Brain Bios Podcast, which spotlights prominent figures in psychology and neuroscience.
We began by discussing Maxcey's work, probing the ethical implications of research studies that aim to exert influence on memory (i.e., induce forgetting). For instance, how might researchers ensure that their participants are sufficiently aware of the risks associated with changes in the accessibility of their memories? Although the Maxcey Lab deals in memories that subjects didn't have prior to walking into the lab—e.g., completely unfamiliar faces—she pondered the consequences of inducing forgetting for different kinds of stimuli, such as those from the deeply personal trove of autobiographical memory. Although the feasibility of impairing access to these items remains questionable at best, Maxcey recalled a student's interest in creating an app that would take advantage of her forgetting paradigm for such a purpose. These sensitive applications, she stressed, would require closer ethical scrutiny.
However, the conversation soon steered in a different direction. What concerned Maxcey the most and ultimately comprised the majority of our discussion were the ethical roles and obligations of the memory scientist—as well as research scientists more generally—in a societal context. Our dialogue ranged from issues of representation in stimulus banks, to barriers of access to research studies, to the need for judicious communication of memory science to the general public. She saw these as the most pressing and thought-provoking considerations of her work, extending clearly beyond the limited regulatory framework of the Institutional Review Board.
Image courtesy of StockSnap/World Maps
The first question of representation came from the (not-so) mindful use of psychological tools. Familiar sights to many researchers in the cognitive and affective sciences are large stimulus sets such as the International Affective Picture System (IAPS) and the Open Affective Standardized Image Set (OASIS). These databases, each composed of hundreds of emotional and neutral images scored on valence, arousal, and other factors, are widely used in the memory literature. Maxcey questioned how the normed scores themselves had been gathered; in other words, what populations determined what kind of emotions the images supposedly evoked? Might an image deemed highly negative by one group—e.g., depictions of the military—be experienced differently by another? IAPS in particular has been criticized for its outdatedness and negligible depiction of cultures outside of North America. Although variability in scoring across cultures has been investigated by researchers in non-North American regions such as Brazil (whose study found few differences), scientists must be aware of the implications of potential variability when working with populations not yet examined. In this way, they must be aware of the social situation and origin of their stimuli, and how data collected with these stimuli impact the ability to generalize findings to certain groups.
Another concern highlighted by Maxcey surrounding the representation of diverse populations lay in the barriers to these individuals' participation in research, including within her own department. No mystery to psychology researchers is the gross overrepresentation of undergraduate university students in the participant pools for behavioral studies (see some historical context here). Beyond the issue of replicability, Maxcey noted that this leads to an underrepresentation of individuals outside of the predominant age range, race, and socioeconomic status of students at these institutions. Studies of memory are not exempt from this problem, which diminishes the scientific findings overall and potentially limits the benefits that underrepresented populations can reap from research conducted without their participation. Maxcey observed that, although the COVID-19 pandemic has led to some advantages as behavioral testing has gone virtual—such as data collection from a wider geographic sample—these circumstances exclude others, such as those without internet access, at the same time.
Image courtesy of Pixabay/Gerd Altmann
In addition to this digital barrier, Maxcey spoke candidly about a department colleague who works with individuals with schizophrenia who are experiencing homelessness. She explained that as universities transition to different study compensation practices, i.e., from providing participants with cash to directly transferring funds via direct deposit, this population—which includes many without a bank account—is left behind. This example underscores the need for research scientists to be cognizant of who their recruitment and research protocol exclude by design, as well as the unique needs of these individuals (e.g., compassion when a no-show occurs or when potential substance abuse is evident). Others may harbor justifiable distrust in universities and other research institutions. Maxcey discussed her time at Tennessee State University, a historically Black college, during which she learned from researchers who embraced the slow yet valuable process of outreach to minority communities to communicate the importance of their participation in research. She stressed that scientists must evaluate and reevaluate the explanation and advertisement of their studies to ensure their research is inclusive of and beneficial for these underserved populations.
As we entered the latter half of our conversation, Maxcey brought to light yet another case of memory science's complex relationship with the public. We spoke about the controversial psychologist Elizabeth Loftus and her involvement as a memory expert in the rape trial of Harvey Weinstein. Arguing for the defense, Loftus highlighted the malleability of memory and its vulnerability to suggestion. Maxcey, who interviewed Loftus in December 2019, explained that Loftus maintains she provides impartial information on memory science to anyone who requests it and therefore should not adjudicate who is allowed to receive her expert testimony. Loftus was heavily criticized, however, by those who point out the discrediting impact of her actions on survivors of sexual assault. Loftus's involvement in the Weinstein trial prompted Maxcey to ask questions about the moral obligations of interfacing with the public as a memory scientist. During the interview, she expressed her support for Loftus's participation, emphasizing that the accessibility of scientists and their work to the public is critical, even in the face of criticism. Of course, the intimate nature of memory as it relates to our identities and lived experiences can make the application of the available science emotionally-laden and even at times contentious.
To explore these difficulties and encourage discourse on the public role of scientists, Maxcey developed a seminar course to allow first-year undergraduates to debate whether Loftus should have testified in the Weinstein case. Students discussed perspective-taking and the pursuit of 'truth' in science, one offering the following: "If Harvey Weinstein is guilty, Elizabeth Loftus's testimony doesn't make him innocent." Clearly, as demonstrated by this lively debate and the wide-ranging views in broader discourse, there remains much to be considered about the delicate relationship of memory experts with those who seek their expertise.
Throughout our discussion of the above themes, Maxcey emphasized her passion for conscious science and conscious science communication. These practices necessitate a research scientist's awareness of and devotion to representation and equity in their work, even (and perhaps especially) in situations where infringements may not be obvious. Research scientists must also responsibly navigate the social dynamics that come along with holding space as a field expert. As we have seen during the pandemic, public trust in scientists and the science they conduct is both intentionally cultivated and fragile. Lastly, scientists must communicate their research clearly. This includes allowing the public easier access to emerging science—to this end, Maxcey has created the KidsVUe journal to encourage students to simplify their scientific writing while still early in their career. In these ways, the unique challenges and opportunities a memory scientist encounters, she argues, can be traced to a larger theme—one of responsibility to be a mindful contributor to and participant in society.
Erin Morrow is a fourth-year undergraduate student at Emory University majoring in Neuroscience and Behavioral Biology. She is the lead research assistant at the Hamann Cognitive Neuroscience Laboratory, where she conducts memory research and neuroimaging analysis. Erin also holds positions with the American Journal of Bioethics Neuroscience and the International Neuroethics Society. As she progresses in her career, she hopes to integrate her pursuits in neuroethics with her academic aspirations in research and engagement in volunteerism.
Morrow, E. (2021). Ethics of Memory Research: The Scientist and Society with Dr. Ashleigh Maxcey. The Neuroethics Blog. Retrieved on , from http://www.theneuroethicsblog.com/2021/06/ethics-of-memory-research-scientist-and.html
Labels: communication Equity Memory representation in the sciences research ethics science communication Society underrepresented minorities in the science

redpajama_set_name: RedPajamaCommonCrawl


HistoGenex has a broad experience in the extraction of nucleic acids from various tissue sources. The close collaboration between scientists and pathologists at HistoGeneX allows for the enrichment of specific tissue components or tumor cells prior to extraction.
In addition to employing commercial molecular extraction products, HistoGeneX has studied the physical and chemical basis of tissue fixation and developed new methods of tissue processing specifically for molecular analyses.
Contact us to learn about our proprietary methods of optimal fixation and tissue processing to obtain high molecular weight RNA and DNA from paraffin embedded tissue samples and cells.


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State Senator Morris Hood District 3 is wanting to connect with a few individuals to see if they would be interested in participating in a short video clip regarding Senate Bills 200 and 201 that would increase penalties for assaulting sports officials.
1. What is your personal story regarding fan / parent aggression?
2. Why do you think this bill would help?
3. What does this bill mean to you?
4. What would the bill mean for the future of sports?
5. What would the bill mean for the future of referee recruits?
6. What could the future of sports look like if nothing is done to help stop aggression against referees?
7. What lesson is aggression against referees teaching our children?
Please contact Nathan Kark, Chief of Staff, if you are interested.


text:
Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood
Srinivasu Puttaswamy, Gennady Lubarsky, CP Kelsey, Xushuo Zhang, D Finlay, James McLaughlin, Nikhil Bhalla
Miniaturized total analysis systems, for the rapid detection of disease biomarkers, with features including high biomarker sensitivity, selectivity, biocompatibility, and disposability, all at low cost are of profound importance in the healthcare sector. Within this frame of reference, we developed a lab-on-a-carbohydrate-microneedle biodevice by integrating localized surface plasmon resonance (LSPR) paper-based substrates with biocompatible microneedles of high aspect ratio (>60:1 length:width). These microneedles are completely fabricated with carbohydrate (maltose) and further coated with poly lactic-co-glycolic acid (PLGA), which together serves the purpose of fluid channels. The porous nature of PLGA, in addition to drawing blood by capillary action, filters out the whole blood, allowing only the blood plasma to reach the biorecognition layer of the developed biodevice. While the use of maltose provides biocompatibility to the microneedle, the axial compression and transverse load analysis revealed desired mechanical strength of the microneedle, with mechanical failure occurring at 11N and 9 N respectively for the compressive and transverse load. For a proof-of-principle demonstration, the developed biodevice is validated for its operational features by direct detection of cystatin C in finger-prick blood and up to a concentration of 0.01 μg/mL in buffered conditions using the LSPR technique. Furthermore, by changing the biorecognition layer, the use of the developed needle can be extended to other disease biomarkers, and therefore the innovation presented in this work represents a hallmark in the state of the art of lab-on-a-chip biodevices.
acsnano.0c05074
ACS Nano
https://doi.org/10.1021/acsnano.0c05074
J.M. and S.V.P. would like to gratefully acknowledge the funding under the Invest Northern Ireland and the European Union?s INTERREG VA Programme, managed by the Special EU Programmes Body (SEUPB) under the Connected Health Innovation Centre (CHIC). J.M. and N.B. would like to acknowledge EPSRC support on this project from the grant EP/TO24437/1 to Ulster University. The authors would also like to thank Dr. Preetam Sharma at NIBEC, Ulster University, for his help in the SEM imaging.
Copyright © 2020 American Chemical Society.
Copyright 2020 Elsevier B.V., All rights reserved.
microneedle lab
LSPR
blood extraction
10.1021/acsnano.0c05074
Accepted ManuscriptAccepted author manuscript, 5.18 MB
Link to publication in ACS Publications
Dive into the research topics of 'Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood'. Together they form a unique fingerprint.
Nanophotonics Engineering & Materials Science 100%
Carbohydrates Engineering & Materials Science 88%
carbohydrates Physics & Astronomy 88%
biomarkers Physics & Astronomy 84%
transverse loads Physics & Astronomy 64%
blood Physics & Astronomy 60%
Biomarkers Engineering & Materials Science 59%
Blood Engineering & Materials Science 58%
Puttaswamy, S., Lubarsky, G., Kelsey, CP., Zhang, X., Finlay, D., McLaughlin, J., & Bhalla, N. (2020). Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood. ACS Nano, 14(9), 11939–11949. [acsnano.0c05074]. https://doi.org/10.1021/acsnano.0c05074
Puttaswamy, Srinivasu ; Lubarsky, Gennady ; Kelsey, CP ; Zhang, Xushuo ; Finlay, D ; McLaughlin, James ; Bhalla, Nikhil. / Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood. In: ACS Nano. 2020 ; Vol. 14, No. 9. pp. 11939–11949.
@article{796113d1fce94315acc36f64bc766bca,
title = "Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood",
abstract = "Miniaturized total analysis systems, for the rapid detection of disease biomarkers, with features including high biomarker sensitivity, selectivity, biocompatibility, and disposability, all at low cost are of profound importance in the healthcare sector. Within this frame of reference, we developed a lab-on-a-carbohydrate-microneedle biodevice by integrating localized surface plasmon resonance (LSPR) paper-based substrates with biocompatible microneedles of high aspect ratio (>60:1 length:width). These microneedles are completely fabricated with carbohydrate (maltose) and further coated with poly lactic-co-glycolic acid (PLGA), which together serves the purpose of fluid channels. The porous nature of PLGA, in addition to drawing blood by capillary action, filters out the whole blood, allowing only the blood plasma to reach the biorecognition layer of the developed biodevice. While the use of maltose provides biocompatibility to the microneedle, the axial compression and transverse load analysis revealed desired mechanical strength of the microneedle, with mechanical failure occurring at 11N and 9 N respectively for the compressive and transverse load. For a proof-of-principle demonstration, the developed biodevice is validated for its operational features by direct detection of cystatin C in finger-prick blood and up to a concentration of 0.01 μg/mL in buffered conditions using the LSPR technique. Furthermore, by changing the biorecognition layer, the use of the developed needle can be extended to other disease biomarkers, and therefore the innovation presented in this work represents a hallmark in the state of the art of lab-on-a-chip biodevices.",
keywords = "POCT, microneedle lab, LSPR, biosensors, blood extraction",
author = "Srinivasu Puttaswamy and Gennady Lubarsky and CP Kelsey and Xushuo Zhang and D Finlay and James McLaughlin and Nikhil Bhalla",
note = "Funding Information: J.M. and S.V.P. would like to gratefully acknowledge the funding under the Invest Northern Ireland and the European Union?s INTERREG VA Programme, managed by the Special EU Programmes Body (SEUPB) under the Connected Health Innovation Centre (CHIC). J.M. and N.B. would like to acknowledge EPSRC support on this project from the grant EP/TO24437/1 to Ulster University. The authors would also like to thank Dr. Preetam Sharma at NIBEC, Ulster University, for his help in the SEM imaging. Publisher Copyright: Copyright {\textcopyright} 2020 American Chemical Society. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
doi = "10.1021/acsnano.0c05074",
pages = "11939–11949",
Puttaswamy, S, Lubarsky, G, Kelsey, CP, Zhang, X, Finlay, D, McLaughlin, J & Bhalla, N 2020, 'Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood', ACS Nano, vol. 14, no. 9, acsnano.0c05074, pp. 11939–11949. https://doi.org/10.1021/acsnano.0c05074
Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood. / Puttaswamy, Srinivasu; Lubarsky, Gennady; Kelsey, CP; Zhang, Xushuo; Finlay, D; McLaughlin, James; Bhalla, Nikhil.
In: ACS Nano, Vol. 14, No. 9, acsnano.0c05074, 22.09.2020, p. 11939–11949.
T1 - Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood
AU - Puttaswamy, Srinivasu
AU - Lubarsky, Gennady
AU - Kelsey, CP
AU - Zhang, Xushuo
AU - Finlay, D
AU - McLaughlin, James
AU - Bhalla, Nikhil
N1 - Funding Information: J.M. and S.V.P. would like to gratefully acknowledge the funding under the Invest Northern Ireland and the European Union?s INTERREG VA Programme, managed by the Special EU Programmes Body (SEUPB) under the Connected Health Innovation Centre (CHIC). J.M. and N.B. would like to acknowledge EPSRC support on this project from the grant EP/TO24437/1 to Ulster University. The authors would also like to thank Dr. Preetam Sharma at NIBEC, Ulster University, for his help in the SEM imaging. Publisher Copyright: Copyright © 2020 American Chemical Society. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
N2 - Miniaturized total analysis systems, for the rapid detection of disease biomarkers, with features including high biomarker sensitivity, selectivity, biocompatibility, and disposability, all at low cost are of profound importance in the healthcare sector. Within this frame of reference, we developed a lab-on-a-carbohydrate-microneedle biodevice by integrating localized surface plasmon resonance (LSPR) paper-based substrates with biocompatible microneedles of high aspect ratio (>60:1 length:width). These microneedles are completely fabricated with carbohydrate (maltose) and further coated with poly lactic-co-glycolic acid (PLGA), which together serves the purpose of fluid channels. The porous nature of PLGA, in addition to drawing blood by capillary action, filters out the whole blood, allowing only the blood plasma to reach the biorecognition layer of the developed biodevice. While the use of maltose provides biocompatibility to the microneedle, the axial compression and transverse load analysis revealed desired mechanical strength of the microneedle, with mechanical failure occurring at 11N and 9 N respectively for the compressive and transverse load. For a proof-of-principle demonstration, the developed biodevice is validated for its operational features by direct detection of cystatin C in finger-prick blood and up to a concentration of 0.01 μg/mL in buffered conditions using the LSPR technique. Furthermore, by changing the biorecognition layer, the use of the developed needle can be extended to other disease biomarkers, and therefore the innovation presented in this work represents a hallmark in the state of the art of lab-on-a-chip biodevices.
AB - Miniaturized total analysis systems, for the rapid detection of disease biomarkers, with features including high biomarker sensitivity, selectivity, biocompatibility, and disposability, all at low cost are of profound importance in the healthcare sector. Within this frame of reference, we developed a lab-on-a-carbohydrate-microneedle biodevice by integrating localized surface plasmon resonance (LSPR) paper-based substrates with biocompatible microneedles of high aspect ratio (>60:1 length:width). These microneedles are completely fabricated with carbohydrate (maltose) and further coated with poly lactic-co-glycolic acid (PLGA), which together serves the purpose of fluid channels. The porous nature of PLGA, in addition to drawing blood by capillary action, filters out the whole blood, allowing only the blood plasma to reach the biorecognition layer of the developed biodevice. While the use of maltose provides biocompatibility to the microneedle, the axial compression and transverse load analysis revealed desired mechanical strength of the microneedle, with mechanical failure occurring at 11N and 9 N respectively for the compressive and transverse load. For a proof-of-principle demonstration, the developed biodevice is validated for its operational features by direct detection of cystatin C in finger-prick blood and up to a concentration of 0.01 μg/mL in buffered conditions using the LSPR technique. Furthermore, by changing the biorecognition layer, the use of the developed needle can be extended to other disease biomarkers, and therefore the innovation presented in this work represents a hallmark in the state of the art of lab-on-a-chip biodevices.
KW - POCT
KW - microneedle lab
KW - LSPR
KW - biosensors
KW - blood extraction
UR - https://pure.ulster.ac.uk/en/publications/nanophotonic-carbohydrate-lab-on-a-microneedle-for-rapid-detectio
UR - https://pubs.acs.org/doi/10.1021/acsnano.0c05074
U2 - 10.1021/acsnano.0c05074
DO - 10.1021/acsnano.0c05074
JO - ACS Nano
JF - ACS Nano
M1 - acsnano.0c05074
Puttaswamy S, Lubarsky G, Kelsey CP, Zhang X, Finlay D, McLaughlin J et al. Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood. ACS Nano. 2020 Sep 22;14(9):11939–11949. acsnano.0c05074. https://doi.org/10.1021/acsnano.0c05074


The United Nations mandated University for Peace (UPEACE) invites applications for need-based scholarships for students starting a master's programme in the academic year 2013-2014. The scholarships are open to students from all countries who demonstrate need and academic excellence.
All financial assistance is based on the assumption that students will contribute as much as they are able to meet their educational and living expenses while studying at UPEACE.
Four 50% tuition waivers: covers 50% of the tuition amount, the student will be responsible for paying the other 50%.
Five 25% tuition waivers: covers 25% of the tuition amount, the student will be responsible for paying the other 75%.
Two tuition deferrals: grant a one year extension of partial or full tuition payment depending upon the award. Deferrals only apply to tuition (ranging from 25% to 100% depending upon the nature of the award available in each Department).
Because of a large amount of requests, UPEACE is unable to provide everyone with a Financial Assistance.


Completely redesigned for 2016 the compact SUV is equally at ease on the road or on the dirt tracks. Ample ground clearance means tricky terrain can easily be overcome, in comfort we might add. The DYNAMIC SELECT handling control fitted as standard allows for 5 driving modes from comfort to sport.
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Permanent all-wheel drive is standard however there's an optional Off-road package with driving modes is available and air suspension too.
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Why not see how much you could save today on a list price GLC of your chosen spec with our totally free quote service.


text:
package com.aspose.words.cloud.drawing;

import java.nio.file.Files;
import java.nio.file.Path;
import java.nio.file.Paths;
import java.nio.file.StandardCopyOption;
import java.util.List;

import com.aspose.storage.api.StorageApi;
import com.aspose.words.api.WordsApi;
import com.aspose.words.cloud.config.Configuration;
import com.aspose.words.cloud.config.Utils;
import com.aspose.words.cloud.convert.AppendDocumentExample;
import com.aspose.words.model.DrawingObjectsResponse;
import com.aspose.words.model.LinkElement;
import com.aspose.words.model.ResponseMessage;

public class GetAllDrawingObjectsFromWordDocumentExample {

	public static void main(String[] args) {
		// ExStart: GetAllDrawingObjectsFromWordDocumentExample
		try {
			// Instantiate Aspose Storage API SDK
			StorageApi storageApi = new StorageApi(Configuration.apiKey, Configuration.appSID, true);

			// Instantiate Aspose Words API SDK
			WordsApi wordsApi = new WordsApi(Configuration.apiKey, Configuration.appSID, true);

			// set input file name
			String fileName = "SampleWordDocument.docx";

			String storage = null;
			String folder = null;

			Path p1=Utils.getPath(AppendDocumentExample.class, fileName);

			// upload input file to aspose cloud storage
			storageApi.PutCreate(fileName, "", "",p1.toFile());

			// invoke Aspose.Words Cloud SDK API to get list of all drawing
			// objects present in a word document
			DrawingObjectsResponse apiResponse = wordsApi.GetDocumentDrawingObjects(fileName, storage, folder);

			if (apiResponse != null && apiResponse.getStatus().equals("OK")) {
				List<LinkElement> linkElements = apiResponse.getDrawingObjects().getList();

				// export all drawing objects to PNG
				for (int objectIndex = 0; objectIndex < linkElements.size(); objectIndex++) {

					ResponseMessage pngImageDataRes = wordsApi.GetDocumentDrawingObjectByIndexWithFormat(fileName,
							objectIndex, "png", storage, folder);

					if (pngImageDataRes != null && pngImageDataRes.getStatus().equals("OK")
							&& pngImageDataRes.getInputStream() != null) {

						String destFileName = "DrawingObject_" + objectIndex + ".png";

						// save the image data
						final Path destination = Paths.get(destFileName);
						Files.copy(pngImageDataRes.getInputStream(), destination, StandardCopyOption.REPLACE_EXISTING);
					}

				}
			}

		} catch (Exception e) {
			e.printStackTrace();
		}
		// ExEnd: GetAllDrawingObjectsFromWordDocumentExample

	}

}


Each of our different roofing services in Barrie, ON is complemented by an unparalleled level of customer service and quality.
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We perform roofing repairs and replacements on residential and commercial properties in the Barrie area.
It's important to choose a qualified and insured roofing contractor.
Each of our different roofing services is complemented by an unparalleled level of customer service and quality. We care about the future integrity of your roof and will make sure that it is repaired or installed properly before we leave your property. We are also fully insured with the WSIB and are accredited by the Better Business Bureau.
At Slippery Slope Roofing, we are confident that you will be more than satisfied turning all of your roofing needs over to us. To find out more about the different roofing services we provide, contact us today.
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text:
Woman charged in partner's stabbing
A 52-year-old woman was taken into custody at Mercy Hospital of Philadelphia yesterday morning, shortly after her common-law husband died there from a stab wound he suffered at her hands, police said.
by By STEPHANIE FARR, farrs@phillynews.com 215-854-4225
It was one of three homicides early yesterday in Philadelphia.
A domestic dispute allegedly led to the woman stabbing her 65-year-old boyfriend of 10 years once in the torso about 12:45 a.m. at the home they shared on Paxon Street near Kingsessing Avenue in Southwest Philadelphia, Homicide Lt. Mark Deegan said.
The victim, whose identity was withheld pending notification of kin, was pronounced dead at 12:52 a.m. at Mercy, said Officer Jillian Russell, police spokeswoman.
The woman, whose identity also was being withheld, was taken into police custody at Mercy shortly after the man's death and was officially charged with murder yesterday afternoon.
About a mile-and-a-half away, and about an hour after that slaying, a small-business owner was fatally shot during a robbery on 65th Street near Paschall Avenue in Southwest Philadelphia, Deegan said.
The 30-year-old man was just steps away from the Super Wings restaurant he owned and the adjoining upstairs apartment he lived in when he was confronted by two men on the street about 1:47 a.m., police said.
The victim, whose name was withheld pending notification of kin, was shot twice in the chest when he wouldn't comply with the robbers' demands, Deegan said.
In the end, the robbers got away with nothing.
The restaurant owner was pronounced dead at the Hospital of the University of Pennsylvania at 2:08 a.m., Russell said.
The bloody morning began at 12:25 a.m. when a man was found dead on Colorado Street near Dauphin in North Philadelphia.
Peter Styles, 26, was shot once in the chest in front of his residence, Deegan said.
He was pronounced dead at Temple University Hospital at 12:38 a.m.
By STEPHANIE FARR, farrs@phillynews.com 215-854-4225


Simplifying your life is not an easy task. I'd say it's something I've been working on since I became a mother. The movement towards simplicity, slow living, mindfulness and minimalism is strong right now yet it's something us humans have been doing for centuries. The fact we are talking about it now is simply a sign that we are overwhelmed with stuff – both information and also, actual crap. This digital age bombards us daily with information and the wave of mass, mindless consumption, fast fashion and seasonal trends have led people to feel out of touch with what really matters. To put it bluntly, we can't see the woods for the trees anymore there's so much crap in our lives and heads.
People are going on technology detoxs, the Marie Kondo way has taken the world by storm and the Netflix documentary The Minimalists has converted many to a simpler way of living. So what's it all about? I thought I'd share a few thoughts on simple living along with some of the ways I've implemented a simpler way of life over the past 3 years.
Laying the groundwork and creating some kind of structure or system for what will essentially make for a simpler day to day and therefore a simpler life!
Choosing a simpler aesthetic – this is not about the style of your home or interior so much as the way you curate it – less mess, more order, less stuff, more space!
Working out our family rhythm. Through trial and error, mostly, I came up with a rhythm that best suits us. From they way in which we start each day, to my quiet cup of coffee, to our after school life, preparing our evening meal (and even thinking about the next two meals the following day), through to the evening rituals that help prepare us for sleep. Establishing our family rhythm has simplified our days and helps us to practise more of what works for us as a family and less of what aggravates us.
Keeping on top of our crap – by this I mean committing to weekly sort outs of those little piles that seem to build up; the daily laundry loads that gather dust and crinkles unless they are folded and put away once dried; a regular look at the toy situation to filter out those that are broken or outgrown; monthly wardrobe checks to eek out and donate that which is too small or no longer used, and so on. Because if you let these things build up they can become overwhelming and laborious. Keeping on top of your crap essentially leads to a simpler life – less unwanted or unused stuff means more space; fewer piles of laundry or mess leads to a sense of peace and calm.
Giving our objects a home. This took me the best part of three decades to accomplish because I was one really disorganised and messy person in my former life. Having a place for everything, and keeping it there, is a triumph – so simple and yet so satisfying. I'm talking your umbrellas, shoes, coats, makeup, kid's art supplies and groceries… EVERYTHING should have it's own rightful home. Gone be the days when you spend half an hour searching for the sticky tape before rushing out to a birthday party, if you know you put it back after using it, then you'll know where to look, saving time, stress and energy!
A daily walk to clear the head. This might not technically come under living a simpler life, but for me getting outdoors and breathing in fresh air, whatever the weather, is good for my soul, and the children's too. We are lucky to live in a leafy part of London, close to the river and a beautiful nature park. I walk every single day whether it's pushing the pushchair along as I run some errands or taking a walk on my own when Oli gets home from work, fresh air is the simplest tonic.
Mindful consumption. I started being more conscious of what I was purchasing when I quit my old job and we lost half our income. Suddenly there was no disposable cash to throw at things and I had to really work hard to budget each month. Despite me now establishing a business of my own which generates a steady income, we by no means spend mindlessly these days. Every purchase is considered and contemplated. I think about how it will fit into our home, whether we have something else that could do the same job and whether we'll still love it in 10 years time. I also think about the impact on the environment a lot more than I did 5 years ago. The long and short is we spend a LOT less these days but we waste a lot less too!
Clearing out your inbox and unsubscribing from marketing mails. Simply put, there is too much junk clogging up the world and we are bombarded with hundreds of messages about how to spend our money each day. If you're receiving too many marketing emails from companies who want to sell you stuff then unsubscribe. You'll be less likely to go on a diversion browsing websites when you should be doing something else and you'll be much less likely to buy more crap that you don't need if you aren't even aware it exists.
Meal planning, thoughtful grocery shopping and homemade snacks. I've written about meal planning before when I adopted this practise a year or so ago. I really enjoy browsing recipe books for inspiration and writing out what we'll be eating for the week ahead before I do our weekly shop. It helps me to stay on track when eating, keep to a budget and waste less. I now make 90% of the kids snacks myself and take packed lunches if ever we're heading out for the day. This means they get a balanced meal and I spend less – win win!
Making the beds. This is perhaps the smallest thing you can do to keep a simple home but once the beds are made, a room has some order about it. Between my husband and I, we make all three beds every single morning which means bedtimes are easier and the bedrooms can be enjoyed at other times of the day.
Remembering that most of our happiest days are the simplest ones. Picnics in the park, gardening, going on a walk or taking the kids swimming. It doesn't take grand gestures or big events to make a wonderful memory. Life is what you make of it and the people in your life are the good stuff, the rest is all fluff!
How do you live a simpler life. Does simplicity even matter to you? I'd love to hear your thoughts on this topic since it is one close to my heart.
This is a great post, These are all things that i have been concidering lately as we are close to bringing anOther baby into our lives. I really want to be more focused on family rhythems And so i feel drwan to living with Less.
I too would love to Hear your snack ideas for the kiddos. Of you list above meal planning is my weak poinT, i hate the weekly shop and guess thats an area i could focus on to improve.
So lovely to read Polly, point 3 is me too, it really is a triumph to have organised places for everything!
So glad you liked the post. Giving things a home is a game changer isn't it!
love this post polly, i try for the same, but have a hard time with my husband because hes more in the hoarder/buyer/not so minimalist camp! have you read simplicity parenting? I just bought it, looks good.
Hi Maddie. it's so hard when you are coming from two different perspectives. i do most of the sort outs and often clear things I know are no longer needed and he doesn't miss them! I have read that book I refer to it often – it's dog earred. I think you'll love it!


text:
Maywood är en förstad väster om Chicago, Illinois, USA med cirka 26 000 invånare. Samhället grundades 6 april 1869 i en del av Proviso Township.

Geografi

Maywood har enligt United States Census Bureau en areal på 32,9 km², allt är land. Den är belägen omedelbart intill Desplanesfloden.

Demografi

Kända personer från Maywood

 Eugene Cernan
 Steven Hunter
 Jim Brewer
 Fred Hampton
 John Prine
 Dennis Franz
 Walter Burley Griffin

Källor

Orter i Illinois
Cook County, Illinois

redpajama_set_name: RedPajamaWikipedia


text:
Category: promotion
Instagram and Poetry Month
April 23, 2017 November 26, 2017 G.D. BurnsLeave a comment
This past April was National Poetry Month, as it has been every year in the U.S. since 1996. While I do sympathize in some part with the quiet criticisms of the celebration, a somewhat trivial designation for the public's attention to turn toward poetry (the point being that after you've taken brief notice of the fact of its existence you can then continue with your general neglect of poetry), I decided to say Bernstein be damned and take on a reflective self-challenge.
I wrote a poem each day this April and posted it to my Instagram feed (not too far of a scroll away). Being my birth month, I associate the Spring and the re-awakening of the earth in this hemisphere with creative activity. But never have I forced myself to compose one poem, each day, for a month, as if I were manually breaking open seeds and thrusting them through to the surface prematurely. Most took in some light (and likes) amidst all the visual splendor of that medium. After week one I gained a steady pace of alternating between writing and posting, then took time to peruse the other poets at work through the convenience of Instagram's self-making engine.
What I found was a strange mix. There was certainly cobwebs-upon-cobwebs of cliched and tired metaphors applauded with fan hearts and digital accolades, but there were also some authentic voices stringing together solid and resounding verse. In some cases, poets in either camp are making the leap from the app to bookstore shelves. My old employer of West Coast indie fame, Powell's Books, has collected a number of such authors for your interest and support with handheld yet plug-less reading. Mostly self-published at first, these poets have made the successful transition to authors-with-contracts by the proving ground of Instagram – which saves the publisher most, if not all, publicity and marketing expenses upon the volume's release.
Has this made poetry a well-read form again, as it once was in the late nineteenth/early twentieth century? Probably not as it once was, and perhaps "well-read" is a generous and not altogether substantial statement. The scrolling must continue on Instagram, indeed, it feeds off such motion which your twitching digits reinforce. What seemed so noble or profound in scant lines once jammed between the colorful plate of food before, and the glorious body come after, may not hold for much longer with its own spine. These are not uncharted waters, but the fog of short attention is always rolling in to obscure our appreciation of the beautiful, and the trash, alike. My only advice would be to read with a critical eye, not just for pleasure.
Posted in poetry, promotion, reflection, UncategorizedTagged Charles Bernstein, Instagram poetry, Instagram poets, National Poetry Month, poetry, tagging
One Page Love Story: Share the Love
March 3, 2015 March 13, 2015 G.D. Burns1 Comment
Almost 3 weeks ago, a volume of love stories featured on the year-long, collaborative Tumblr project One Page Love Story was released into the world for purchase on Kindle or in paperback. Affirming the continued existence of physical books, this volume is printed on nice, warm colored stock and has a matte colored cover, as you can see above in one of its new homes for the feast of public eyes, Strand Books! However, this Saturday March 7th and Sunday the 8th are Kindle free days in which you can read and revel in the work that's been brought together.
The collection of writers involved in this project were prompted by author Rich Walls to participate in the crafting of short fictional love stories of their own composition, submitting one-a-day over a period of 10 days. One Page Love Story: Share the Love is the culmination of these multiple efforts. A portion of the proceeds go to First Book, a charity which "is determined to see that all children, regardless of their economic conditions, can achieve more in school and in life through access to an ongoing supply of new books," and so I encourage Kindle readers to consider purchasing a paperback copy for this sake for themselves or as a gift.
I am quite proud to be amongst a hearty crew of working authors who have chosen to support such a worthy cause and create work in this surprisingly tough constraint & format. Each one manages to illuminate a wavelength in the spectrum of love's expression within human life. Thank you to Rich for making this all possible and to the many readers, writers and lovers in this world, striving for those peak experiences of consciousness and communion.
Posted in promotion, publicationTagged First Book, Gary Dale Burns, love stories, one page love story, Rich Walls


If you plan on using a elaborate or print sheet of paper with your invitation, consequently choose that first. You may choose the other colors of cardstock for your invitation from within that pattern. Choose a couple different colored sheets mainly because layers look great. Try less heavy shades and darker tones and determine which appears best with your pattern as well as the style you've chosen for your invitation. Don't forget the text piece, which is usually a white colored or cream cardstock, although can also be a light shade of an color that is readable when printed with black printer ink. You can also use a translucent newspaper on your invitation which works well as an overlay piece or directly as the written text sheet.
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Incontinence Samples are a great way to try out several styles of briefs, diapers or pads, liners, or different underpads without having to buy an entire bag of each. Try out a sample pack and find the incontinence solution that is perfect for you.
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Join Transfer (before 5.00 P.M everyday) from/to Thongsala Pier to/from resort is at 250 THB per person one way and Free for children under 12 years old. Please call the resort for pick up 1 day before arrival.
Christmas Reservation: A minimum stay is 7 nights, and arrival date is on or before 22 Dec only.
New Year Reservation: A minimum stay is 7 nights, and arrival date is on or before 28 Dec only.


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Podere Vista is an old refurbished country house consisting of a manor house and two cottages sorrounded by wide meadows, vineyards and olive yards. Situated on the slope of the hill opposite San Gimignano (Siena), Podere Vista offers a panoramic view of the old town and of the stunning hilltop skyline of towers. Guests can enjoy wide meadows equipped with sun beds, lounge chairs, and tables, and an outdoor swimming pool, that faces San Gimignano and the surrounding hills complete with patio, sun beds, and bath towels.?Each apartment is self-catering and available with a private, outdoor area with chairs and tables, and a personal barbecue to eat, relax, and enjoy the beautiful view. Vista also has a room where our guests can taste the dishes of the Tuscan tradition, prepared with the care and passion by the host family. Here your palate will be lulled by the flavors of the natural and simple ingredients while your eyes will relax mirroring the green of the hills, dark at dusk.?Every night you will be offered a different menu, in order to let you know the richness of the Tuscan tradition, which, sometimes also welcomes particular gastronomic experiments. ?Cost of the Menu from appetizer to dessert: 25,00 euro (wine not included).
On the first floor of the manor house, the apartment is composed of a little kitchen, wardrobe, lumber-room, bathroom with shower and a double bedroom with view of the countryside and of the swimming pool. Tv-Sat. Outside, protected by an olenader hedge, there is a private space equipped with barbecue, table, chairs, armchairs and sunshade parasol.
Independent cottage composed of a living-dining room with sofa that can be transformed in a large bed, kitchenette, one double bedroom, with bathroom and shower, one double bedroom (Large bed) with an arm chair that can be transformed in a single bed, bathroom with shower. One third bathroom is available for guest sleeping in the sofa-bed of the sitting-room. Tv-Sat. From the kitchenette, from one double bedroom and its bathroom you can see San Gimignano. The living room and the kitchenette overlook a private open space, in the shade of a medlar, equipped with table, chairs, armchairs and barbecue from where you can enjoy a wonderful view on San Gimignano.


text:
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No matter where your next holiday destination is going to be, it is important to plan in advance so that you can make some cost savings. After all, if there is one thing most of us are guilty of, it is spending more money than we need to while overseas. You can use the tips below to save money while traveling no matter where in the world you are heading. This will enable you to save some funds for doing more activities!
There is only one place to begin when it comes to holiday savings, and this is by eating in local restaurants and establishments while overseas. If you eat in a tourist spot, you are going to pay way over the odds. You will usually find that you get more food and a better standard of service for less in a local restaurant. Not only this, but it will give you a true taste of the local cuisine in the place you are visiting. And, isn't that what traveling is all about?
There is no need to spend a fortune on taking a taxi everywhere. Most places around the world have public transport systems now, so do your research before traveling. You should see whether you can get any group tickets or saver passes.
Thanks to the Internet it is easier to buy tickets for events and activities in advance than ever before. Websites like https://www.theticketmerchant.com.au/ are great if you are planning on going to a concert or sporting event while on holiday. Make sure you do a bit of research online first, though, as with certain tickets, for example, theme park tickets, there may be insider tips on how to get cheaper tickets.
You don't have to go on a camping holiday, but you could incorporate a bit of camping into your trip in order to save money on accommodation. Not only is this a great way to save but also you can enjoy some of the most stunning scenery. There is something about looking at the stars while camping that seems so much better when in a different country.
A lot of people simply overlook the prospect of free activities. We have all become so accustomed to paying for everything that we do! However, there are plenty of fun things to do that won't cost a penny. Head to http://www.wimdu.co.uk/blog/free-entry-12-activities-in-europe/ for some examples of some of the best free things to do across Europe.
Do not always stay in the main tourist areas, as it will always be more expensive over there. Get off the beaten path, maybe leave your comfort zone a bit, and start exploring areas in the country you're traveling in that are still pretty unknown to most travelers. This is where you start making unforgettable stories. Everything will be cheaper as well because these places are not catered yet to tourists. A good start is to find an Airbnb in a local neighborhood instead of sleeping in a hotel in the center of the city.
Get $40 travel credit on Airbnb from us!
As you can see, there are many different ways that you can save money, irrespective of your destination. Simply follow the advice that has been provided above and you should be able to lower your expenses overall so that your money goes a lot further.


The Central Government's decision on recommendations of the 7th Central Pay Commission (CPC) on Allowances published in Gazette of India yesterday i.e. 6th July, 2017; All allowances are given effect from 1st July 2017; Concerned Ministries advised to issue their Orders on Allowances governed by them immediately so that the revised rates of allowances get reflected in the current month's Salary Bills of the Government employees.
Concerned Ministries have now been advised to issue their Orders on Allowances governed by them immediately so that the revised rates of allowances get reflected in the current month's Salary Bills of the Government employees.
COBRA Allowance granted to CRPF personnel in Naxal hit areas increased from ₹8400 - ₹16800 pm to ₹17300 – ₹25000 pm Modified Field, Field & Highly Active Field Area Allowances increased from ₹1200 - ₹12600 pm to ₹6000 – ₹16900 pm.
High Altitude Allowance increased from ₹810 - ₹16800 pm to ₹2700 – ₹25000 pm.
Territorial Army Allowance increased from ₹175 - ₹450 pm to ₹1000 –₹ 2000 pm.
Ceilings of Deputation (Duty) Allowance for Defence Personnel increased from ₹2000 - ₹4500 pm to ₹4500 - ₹9000 pm.
Detachment Allowance increased ₹165 - ₹780 per day to ₹405 – ₹1170 per day.
Para Jump Instructor Allowance increased from ₹2700/3600 pm to ₹6000/10500 pm.
Hospital Patient Care Allowance/Patient Care Allowance increased from ₹2070 - ₹2100 pm to ₹4100 – ₹5300 pm.
Cycle Allowance not abolished - rates doubled from ₹90 to ₹180 pm for functional requirements of Postmen in Posts and Trackmen in Railways.


So I'm sure this comes as a suprise to literally none of you. You're all like: Um ya.. No @!#$ Sage. I mean, just wow. Duh! I guess I thought I could handle it. Anyway, let me explain something. I'm a bit of a loner and tend to stay at home or go on walks in nature. neither of these things really have people pushing their stupid nonsense on me.
And by stupid nonsense, I mean calling me male, a boy, young man, and all of that. I've withdrawn so far into myself that most of the time it just bounces off the personality I have created for myself. a cocky, arrogant young man who doesn't give a @!#$ about anything anyone thinks. But it is a lie. a total lie. But at the same time I have a sort of dual personality. but lately I realised that it wasn't what I thought it was. I figured it was a male and female one. nope. It's a child personality and an adult one. Actually, My other half was almost finished writing a post about the same thing. But we had a little run in with some shoe shopping and it all just shut down. So I need to get my full driver's licence. my grandmother is helping me with that. And she figured it was a waste to just drive around for the sake of it. We ended up going round to various nurseries looking for gardening shoes. first we went to a hardware store.
Hehehe. It's from a show called Natsume yujin cho. I really liked it, soo I bought it. last one too.
It just hurts in a way that I can't explain or bear. I guess the nail in the coffin was looking at a picture of the "real" me against a picture of one of my in-game avatars and just looking at the fake me and kinda just wanting to hug the 'fake' me. Chances are it probably looks like I should have. but way more awesome and stuff. But I guess I'm pretty handsome so who knows? I probably am quite the looker haha. Oh, Here's the thing I was talking about. I'm not showing you a picture of me cause It hurts to look at. So why the heck haven't I transitioned yet?
I've been afraid that no matter how hard I tried I still would look horrible. and honestly, I could get FFS (facial feminization surgery) if I still looked ugly except I don't want anything to do with surgery. very dangerous business. one slip and there goes a nerve. can't feel your face.
I bet most of you haven't heard of that one. 🙂 but what would I know? *Sigh.* I'm so full of it. I'm not really full of myelf. I'm a pisces for crying out loud! (ps: astrology is more complicated than that) but you didn't hear that from me. oh god he's coming back. Nope. "have you been telling people that you're actually super sensitive"? "Nope" "Mkay then. Just keep on being dashingly handsome and stuff.
hehe. Sorry. I'm so sick of having a broken mind. So I make fun of it at every opportunity. I would swear I was totally okay with my appearance a few weeks ago. But not now. honestly. so over this.
I guess I should start transitioning then. Also, screw waiting another 6 or 7 months to see the dump psycologist again. I'm taking it into my own hands. serious buisness this is. I'm going to go. can't stand thinking about it anymore. Oh, and this way I can change my bone structure. That's pretty awesome if you ask me. And for all you naysayers kindly explain why my face hurts? it just needs my dedication and hard work. which it has not got as of yet.
My hair is getting long!
I'm not talking about the trans being a mental thing, but rather the things that can come along with it. dissociation, multiple personalites and that sort of thing. It's a bit of a total mess. Plus I'm more inclined to identify as neither gender in the first place. but people can't handle that.
In Australia there are so few people that deal with this sort of thing and the waiting times are so absurdly long. I see no reason not to persue other methods in the meantime?
But thank you for taking the time to say that. I really appreciate it.
Oh dear, I think a bit of my issues with psychiatrists got into my response to your post. I do identify as female though born male. In the UK the usual route to hormones and maybe SRS is via Gender Identity Clinics, staffed largely by shrinks. Waiting times exceed 13 months for first appointment plus another six for second, at which time they may or may not decide to allow you hormones. I've found a wonderful female doctor who treats me as an adult that knows her own mind and issues me with the hormones I need. But I am one of the lucky ones.
My heart and my support truly goes out to you my friend.
Be careful love. Pursuing hormone treatment outside the normal channels is dangerous. You can get sick, experience organ failure, and even die if you're not careful.
I hate to admit it, But you are probably right. I do need to be careful. It's kinda like: don't try this at home kids! I'm a profesional… (which I am NOT LOL!) Truth be told I've been toying with all sorts of different stuff over the last year or so. all of it has worked a little. it's why I can't sleep on my tummy without my 'chest' hurting. sigh.


text:
"Science, like art, music and poetry, tries to reduce chaos to the clarity and order of pure beauty." DW Bronk Tweet this quote
Did you know? Mass of Mercury (330 sextillion kg) is 20 x Mass of dwarf planet Eris (16.6 sextillion kg) Tweet this comparison
Land Area of Chile
Land Area of Chile (12,290 km^2)
/fact/land-area-of-chile
If Land Area of Chile (12,290 km^2) was a standard unit ...
Land used for agriculture in United States (2011) (305,200 km^2)...more would be 25 x Land Area of Chile
Forest in Canada (2011) (303,900 km^2)...more would be 25 x Land Area of Chile
Other land in China (2011) (62,200 km^2)...more would be 5 x Land Area of Chile
Land Area of Tanzania (61,500 km^2)...more would be 5 x Land Area of Chile
Land used for agriculture in Canada (2011) (60,600 km^2)...more would be 5 x Land Area of Chile
Forest in China (2011) (60,300 km^2)...more would be 5 x Land Area of Chile
Land used for agriculture in Uganda (2011) (31,280 km^2)...more would be 2.5 x Land Area of Chile
Land used for agriculture in Australia (2016) (31,170 km^2)...more would be 2.5 x Land Area of Chile
Forest in Finland (2011) (25,030 km^2)...more would be 2 x Land Area of Chile
Land Area of Chad (24,800 km^2)...more would be 2 x Land Area of Chile
Land Area of Malawi (24,400 km^2)...more would be 2 x Land Area of Chile
Land Area of Ukraine (24,220 km^2)...more would be 2 x Land Area of Chile
Land used for agriculture in Eritrea (2011) (12,470 km^2)...more would be about as big as Land Area of Chile
Land used for arable in Turkmenistan (2011) (12,320 km^2)...more would be about as big as Land Area of Chile
Land used for permanent crops in Turkmenistan (2011) (12,320 km^2)...more would be about as big as Land Area of Chile
Land used for permanent pasture in Turkmenistan (2011) (12,320 km^2)...more would be about as big as Land Area of Chile
Land used for arable in Venezuela (2011) (6,180 km^2)...more would be 1/2 of Land Area of Chile
Land used for permanent crops in Venezuela (2011) (6,180 km^2)...more would be 1/2 of Land Area of Chile
Land used for permanent pasture in Venezuela (2011) (6,180 km^2)...more would be 1/2 of Land Area of Chile
Forest in Zambia (2011) (6,110 km^2)...more would be 1/2 of Land Area of Chile
Other land in Turkey (2011) (4,930 km^2)...more would be 2/5 of Land Area of Chile
Land used for arable in Liberia (2011) (3,130 km^2)...more would be 1/4 of Land Area of Chile
Land used for permanent crops in Liberia (2011) (3,130 km^2)...more would be 1/4 of Land Area of Chile
Land used for permanent pasture in Liberia (2011) (3,130 km^2)...more would be 1/4 of Land Area of Chile
Land used for arable in Zambia (2011) (2,480 km^2)...more would be 1/5 of Land Area of Chile
Land used for permanent crops in Zambia (2011) (2,480 km^2)...more would be 1/5 of Land Area of Chile
Land used for permanent pasture in Zambia (2011) (2,480 km^2)...more would be 1/5 of Land Area of Chile
Forest in Romania (2011) (2,440 km^2)...more would be 1/5 of Land Area of Chile
Other land in Mexico (2011) (2,410 km^2)...more would be 1/5 of Land Area of Chile
Land used for agriculture in Rwanda (2011) (1,240 km^2)...more would be 1/10 of Land Area of Chile
Forest in Nigeria (2011) (1,240 km^2)...more would be 1/10 of Land Area of Chile
Other land in Azerbaijan (2016) (1,230 km^2)...more would be 1/10 of Land Area of Chile
Land used for arable in Senegal (2011) (1,220 km^2)...more would be 1/10 of Land Area of Chile
Land used for arable in Zimbabwe (2011) (1,220 km^2)...more would be 1/10 of Land Area of Chile
Land used for permanent crops in Senegal (2011) (1,220 km^2)...more would be 1/10 of Land Area of Chile
Land used for permanent crops in Zimbabwe (2011) (1,220 km^2)...more would be 1/10 of Land Area of Chile
Land used for permanent pasture in Senegal (2011) (1,220 km^2)...more would be 1/10 of Land Area of Chile
Land used for permanent pasture in Zimbabwe (2011) (1,220 km^2)...more would be 1/10 of Land Area of Chile
Land Area of Croatia (620 km^2)...more would be 1/20 of Land Area of Chile
Land Area of Portugal (620 km^2)...more would be 1/20 of Land Area of Chile
Other land in France (2011) (610 km^2)...more would be 1/20 of Land Area of Chile
Other land in Philippines (2011) (610 km^2)...more would be 1/20 of Land Area of Chile
Land Area of Brunei (500 km^2)...more would be 1/25 of Land Area of Chile
Land used for agriculture in Switzerland (2011) (500 km^2)...more would be 1/25 of Land Area of Chile
Other land in Virgin Islands (2011) (490 km^2)...more would be 1/25 of Land Area of Chile
Land used for arable in Guatemala (2011) (310 km^2)...more would be 1/40 of Land Area of Chile
Land used for permanent crops in Guatemala (2011) (310 km^2)...more would be 1/40 of Land Area of Chile
Land used for permanent pasture in Guatemala (2011) (310 km^2)...more would be 1/40 of Land Area of Chile
Other land in Israel (2011) (304 km^2)...more would be 1/40 of Land Area of Chile
Land Area of Belgium (250 km^2)...more would be 1/50 of Land Area of Chile
Land Area of Morocco (250 km^2)...more would be 1/50 of Land Area of Chile
Land used for arable in Latvia (2011) (250 km^2)...more would be 1/50 of Land Area of Chile
Land used for arable in Lithuania (2011) (250 km^2)...more would be 1/50 of Land Area of Chile
Land used for permanent crops in Latvia (2011) (250 km^2)...more would be 1/50 of Land Area of Chile
Land used for permanent crops in Lithuania (2011) (250 km^2)...more would be 1/50 of Land Area of Chile
Land used for permanent pasture in Latvia (2011) (250 km^2)...more would be 1/50 of Land Area of Chile
Land used for permanent pasture in Lithuania (2011) (250 km^2)...more would be 1/50 of Land Area of Chile
Land used for agriculture in Portugal (2011) (246.1 km^2)...more would be 1/50 of Land Area of Chile
Land used for arable in Portugal (2011) (124 km^2)...more would be 1/100 of Land Area of Chile
Land used for permanent crops in Portugal (2011) (124 km^2)...more would be 1/100 of Land Area of Chile
Land used for permanent pasture in Portugal (2011) (124 km^2)...more would be 1/100 of Land Area of Chile
Land Area of Slovenia (122 km^2)...more would be 1/100 of Land Area of Chile
Other land in West Bank (2011) (121.4 km^2)...more would be 1/100 of Land Area of Chile
Land used for agriculture in Jordan (2011) (61.6 km^2)...more would be 1/200 of Land Area of Chile
Land used for arable in Guinea (2011) (60.9 km^2)...more would be 1/200 of Land Area of Chile
Land used for permanent crops in Guinea (2011) (60.9 km^2)...more would be 1/200 of Land Area of Chile
Land used for permanent pasture in Guinea (2011) (60.9 km^2)...more would be 1/200 of Land Area of Chile
Forest in Jamaica (2011) (49.8 km^2)...more would be 1/250 of Land Area of Chile
Forest in Israel (2011) (31.24 km^2)...more would be 1/400 of Land Area of Chile
Land used for agriculture in New Caledonia (2011) (31.2 km^2)...more would be 1/400 of Land Area of Chile
Land used for agriculture in Brunei (2011) (12.5 km^2)...more would be 1/1000 of Land Area of Chile
Forest in Samoa (2011) (6.04 km^2)...more would be 1/2000 of Land Area of Chile
Land used for agriculture in Samoa (2011) (1.24 km^2)...more would be 1/10000 of Land Area of Chile
Is That a Big Number? - the book - is now available from all good booksellers.
"This is a fun and riveting book. Written in an accessible and engaging way, it is unputdownable." Frost Magazine
Click here to learn more about it.
Click here for Podcast: Andrew Elliott interviewed for New Books Network.


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La Rascie (en serbe : Рашка, Raška) est l'une des plus importantes principautés serbes du Moyen Âge. Établie à la fin du e siècle même si avant il existait un territoire nommé Serbie sous le règne de Ostroilo, c'est à partir de celle-ci qu'est constitué le royaume de Serbie puis l'Empire serbe, après l'arrivée au pouvoir des Nemanjić. Par la suite, le terme de Rascie reste utilisé pour désigner l'ancienne principauté aussi bien que la Serbie d'alors. Ainsi, au , la principauté du knèze Lazar Hrebeljanović (Lazareva zemlja), est désignée par les Hongrois comme royaume de Rascie.

Localisation

La Rascie est, au Moyen Âge, une principauté centrale de la Serbie médiévale. Elle est ainsi nommée d'après la rivière Raška.

La Rascie a comme capitale la ville de Ras, située près de l'actuelle cité de Novi Pazar. Au faîte de sa puissance, elle englobe la totalité du Monténégro actuel ainsi que l'Herzégovine, toute la côte croate jusqu'à Solin (Croatie), mais sans la ville de Raguse ; cette dernière est alors une ville libre qui paye un tribut aux souverains serbes afin de garder son autonomie politique.

Aujourd'hui, en Serbie, on désigne par « Rascie » le district de Raška, qui ne correspond qu'à une petite partie de la Rascie médiévale. Les musulmans du Sud-Ouest de la Serbie nomment Sandžak la région où ils sont légèrement majoritaires, du nom du sandjak de Novipazar, ancienne division administrative de l'Empire ottoman.

Histoire

Invités par l'empereur byzantin Héraclius, les Serbes peuplent plusieurs territoires balkaniques dès le , dont la Rascie. Celle-ci, organisée en principauté autonome sous souveraineté byzantine, est dirigée au départ par l'archonte inconnu qui a mené les tribus serbes dans les Balkans, puis, bien que l'on n'ait pas de renseignements à ce sujet, probablement par ses descendants. Le premier dirigeant serbe dont on connaît le nom est Višeslav (sans doute descendant de l'archonte inconnu), contemporain de Charlemagne, qui règne en Rascie à la fin du . Ses descendants ont des difficultés à préserver l'autonomie de la Rascie, du fait des guerres entre Byzance et les Bulgares. Au , l'arrière-petit-fils de Višeslav, Vlastimir, fonde la dynastie des Vlastimirović, qui règne jusqu'en 950. Sous le règne de Mutimir, fils de Vlastimir, les Serbes de Rascie sont christianisés par des émissaires byzantins, bien que le paganisme perdure encore longtemps, jusqu'à l'avènement de saint Sava. En 924, l'empereur bulgare Siméon annexe temporairement la Rascie, mais à sa mort en 927, un descendant de Vlastimir, Časlav Klonimirović, s'échappe des prisons bulgares, et restaure l'État de Rascie. Soutenu par Byzance et l'empereur Constantin VII Porphyrogénète, il en profite pour conquérir les territoires serbes voisins de Bosnie, Travounie et Paganie. Il repousse plusieurs fois les Hongrois, mais après sa mort au cours d'une bataille en 950, la Serbie est divisée par Byzance, et la Rascie incorporée dans le thème de Serbie (thema servia).

Pendant plus d'un siècle, la Rascie occupe une importance secondaire parmi les États serbes. Dirigée par un stratège byzantin, elle retrouve son éclat seulement à la fin du . Entretemps, elle est libérée dans la première moitié du  par Stefan Vojislav, prince de Dioclée, qui chasse le dernier stratège byzantin, Theophilos Erotikos. À la suite du déclin de la Dioclée, la Rascie devient indépendante en 1091, sous le règne du joupan Vukan, ancien courtisan et allié du roi Bodin de Dioclée. Après plusieurs victoires sur Byzance, Vukan parvient à agrandir la Rascie vers le sud, englobant une partie de l'actuel état du Kosovo. La Rascie s'étend alors, au sud-est, jusqu'à la ligne Ras-Zvečan-Peć. Vukan ne réussit cependant pas à aller au-delà de la vieille ville impériale de Lipljan, abandonnée aussitôt conquise, à cause de la présence d'un fort contingent byzantin.

Après la mort de Vukan, la Rascie, prise par l'empereur byzantin Jean II Comnène, au début de son règne, est contrainte de reconnaître l'autorité de ce dernier, malgré une courte libération de la ville de Ras de 1127 à 1129. Au cours des conflits entre Byzance et la Hongrie, les joupans de Rascie prennent parti pour cette dernière, et la Rascie est maintes fois la proie de destructions et de pillages. Dans leurs efforts pour se libérer de la suzeraineté byzantine, les grands joupans de Rascie parviennent toutefois à agrandir les frontières de leur territoire. La Rascie s'étend alors à l'est du mont Kopaonik, recouvrant la vallée de la Toplica et s'étendant jusqu'à la rive gauche de la Morava occidentale, au sud jusqu'à la ligne Zvečan-Peć et au nord jusqu'au mont Jastrebac. Mais à la suite de la victoire de l'empereur Manuel  Comnène sur les Hongrois, elle se retrouve complètement soumise, et l'empereur nomme les grands joupans à son gré, de 1155 à 1163.

En 1163, l'empereur confie le fief de Dubočica à Stefan Nemanja, seigneur d'un domaine princier de Rascie orientale, des environs de la vallée de la Toplica. Il lui octroie par la même occasion le droit de régner comme joupan. Cela lui confère un avantage certain par rapport à ses trois frères, tous seigneurs d'autres domaines des territoires serbes. Après des bouleversements politiques, le grand joupan de Rascie, Desa, est chassé en 1165. Tihomir, frère de Nemanja, lui succède. Cependant, l'autonomie des territoires de Nemanja lui vaut l'opposition de ses frères, qui le capturent. Ayant réussi à s'enfuir, Nemanja rassemble ses partisans, chasse ses frères en 1166, se proclame grand joupan de Rascie. Aidé par Byzance, Tihomir tente de reconquérir la Rascie, échoue, et périt en 1168 au combat. Nemanja essaie alors de s'affranchir de la domination byzantine, mais privé de l'aide de la Hongrie, il doit attendre la mort de Manuel , en 1180, pour progressivement libérer la Rascie, et rassembler les autres territoires serbes, en particulier la Dalmatie et la Dioclée. À la fin du , Byzance est obligée de reconnaître l'indépendance de la Serbie en 1185.

À partir de cette période, l'histoire de la Rascie se confond avec celle de la Serbie médiévale (voir l'article histoire de la Serbie). Stefan Nemanja est le premier de la dynastie des Nemanjić, qui dirige le royaume pendant plus d'un siècle et demi.

Notes et références

Voir aussi

Articles connexes
 Histoire de la Serbie, Histoire des Serbes

 Liste des souverains serbes, Ostroilo, Višeslav (prince serbe)
 Rasciens
 Dioclée, Paganie, Rascie, Travonie, Zachlumie
 Guerres byzantino-serbes

Histoire de la Serbie médiévale
Ancien pays des Balkans
Provinces historiques d'Europe
Royaume de Rascie


HITMAN ABSOLUTION follows cold-blooded assassin Agent 47™ as he takes on his most dangerous contract to date. Betrayed by those he once trusted, and hunted by the police, he suddenly finds himself at the center of a dark conspiracy and must embark on a journey through a corrupt and twisted world. Showcasing IO Interactive\'s new proprietary Glacier 2™ technology, the game has been built from the ground up. Boasting a cinematic story, distinctive art direction and highly original game design, HITMAN ABSOLUTION combines much-loved classic gameplay with features never seen before in the Hitman franchise.


text:
Radha: From Gopi to Goddess
Harsha V. Dehejia (Editor)
In tracing the evolution of Radha from that of a gopi to a goddess one traverses not only a span of several centuries, but travels through cultural divides, political dynasties and philosophical debates. She occupies a space which moves from the aesthetics of shringara rasa to the theology of shringara bhakti, from the madhurya of Pushtimarg Vaishnavism to the prema of Gaudiya Vaishnavism, taking in its stride the philosophies of Advaita and Dvaita, the traditions of Shakti and Shakta, she takes us from the devotional poetry of Bhaktikal to the courtly poetry of Ritikal and even beyond to the modern poetry of Adhunikkal. Radha is both kamini and ramani, desirable and beautiful, and through her persona we understand the role of kama or desire in the workings of the human mind and especially in the aesthetics of shringara, she is both a gopi and a nayika and through her we feel the presence of Krishna in Vrindavana and the opulence of the Vaishnava Rajput courts, she is a devi in the temples of the Gaudiyas and through her we are able to worship Krishna, and finally she is even a kalankini or the defiled one and through her we are privy to the folk literature of Bengal and modern middle class psychology of the bhadralok. Radha: From Gopi to Goddess portrays in poetry and painting, dance and drama, sculpture and icon, songs and stories how Radha occupies a special place in sociology and psychology, aesthetics and theology.
149.40 134.46 $ 166.00 $
Harsha V. Dehejia
Harsha V. Dehejia has a double doctorate, one in Medicine and the other in Ancient Indian Culture, both from the University of Mumbai. He is also a Fellow of the Royal College of Physicians of London, Glasgow and Canada, all by examination. He is Professor of Religion at Carleton University in Ottawa, Canada where he teaches Indian Aesthetics. He has published three books, The Advaita of Art, Parvatidarpana (both by Motilal Banarsidass, Delhi) and Parvati, Goddess of Love (by Mapin, Ahmedabad). He is Curatorial Advisor to the Canadian Museum of Civilization. Dr. Dehejia is a practicing physician and lives in Ottawa.
Saundarya: The Perception and Practice of Beauty in India
A Celebration of Love: The Romantic Heroine in the Indian Arts
Gods Beyond Temples
Rasikapriya: Ritikavya of Keshavdas in Ateliers of Love
Magic of Indian Weddings: Timeless Traditions, Sacred Customs
Tantra, Mantra, Yoga & Spiritual Bliss
Vijnana Bhairava: The Practice of Centring Awareness
Sri Chakra
Reviews in total
Title	Radha: From Gopi to Goddess
Author	Harsha V. Dehejia
Edition	1st. ed.
Publisher	Niyogi Books
length	260p., Colour; Illustrations; 31cm.
Subjects Art and Architecture > Religion & Spirituality > Iconography > Hinduism


text:
A Tribute To Road Warrior Animal
From: What A Rush with Road Warrior Animal
In this final episode of "What A Rush," Animal's co-host Joe Roderick will give his thoughts and share his memories about the man, the myth, and the pro wrestling legend who was taken from us so suddenly and tragically, Joseph "Animal" Laurinaitis.
Listen in as not only Joe takes your along for his stories, but also Animal's peers, co-workers, and friends will reminisce as well, including "Precious" Paul Ellering, Shane "Hurricane" Helms, Kevin Sullivan, Matt Cardona, Bill Apter, Larry ... See More Zbyszko, Gary Michael Cappetta, Billy Gunn, "The Franchise" Shane Douglas, "The Million Dollar Man" Ted DiBiase, Tony Schiavone, Nikita Koloff, and Scott Norton.
Animal was one of the first "name" superstars to come aboard the Creative Control Network, and give us some credibility. He was always generous with his time, his wisdom, and his willingness to share and interact with his audience. It's been an honor to upload and promote this podcast.
RIP Animal.
Blue Chew was a long time supporter of "What A Rush," and we thank them so much for choosing this show to promote their products for so long. If you'd like to try a free month for only $5 shipping, please go to bluechew.com and use the code LOD.
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