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CBS's show The Doctors show touches a families life in the Smoky Mountains
Home | Blog | Cabin Rentals | CBS's show The Doctors show touches a families life in the Smoky Mountains
(From left to right) Charlie, Auntie Belham's Cabin Rentals owner John Madewell and Carmelita pose in front of the couple's vacation rental.
Every day at Auntie Belham's Cabin Rentals we are fortunate to meet a variety of guests from all over the world. Each family has a story to tell, and each story is very different.
When we first met Charlie and Carmelita from Nashville, we knew that they were special.
Their Story
Every day Charlie would walk to meet Carmelita after work, but one day he wasn't there. With a sinking feeling that something bad had happened to her husband, Carmelita drove with her grandchildren in the car to the walking route he normally took. The uneasy feeling that she felt, however, did not prepare her for what she saw.
While walking, Charlie had been struck by a moving car and was currently being rushed to the nearest hospital that was 20 miles away. By the time he arrived, doctors gave him a slim chance of survival and he had lost all but 10% of his body's blood supply.
Charlie spent five days in the ICU at Vanderbilt Hospital in Nashville. What happened next was truly miraculous.
Charlie and Carmelita spending time with members of the Auntie Belham's Cabin Rentals Family.
When Charlie was still in the hospital, the doctor told him that the prosthetic arm that he wanted for Charlie would cost upwards of $60,000. The couple did not have that kind of money, so they did what they could do–pray.
At this time Carmelita also took it upon herself to try and find someone who could help her husband. During her quest to find a solution, Carmelita wrote the producers of CBS's show The Doctors. Unbeknownst to Charlie, Carmelita told the show's executives all about her husband's accident, his miraculous recovery and the cost of the prosthetics.
It wasn't until Dr. Travis Stork, an E.R. physician on the show, showed up at the couple's home that Charlie even knew what his wife had been up to. During the show, Dr. Travis told Charlie that the Hanger Clinic offered to gift him a brand new prosthetic. For Carmelita, who had sacrificed so much to help take care of her husband, Dr. Travis explained that a Gatlinburg cabin company was gifting her and her family a four night and five day all-expenses paid Smoky Mountain vacation. That's where we came in.
After hearing Charlie and Carmelita's story, we knew that there was something special about their family, and we wanted to do our part in helping the couple relax and unwind. We were fortunate to have them as guests this past weekend, and we look forward to seeing them again in the future.
Three generations of family traveled together to join Charlie and Carmelita during their Smoky Mountain vacation.
While They Were Here
Because it wouldn't be a true vacation without being surrounded by the ones they love, Charlie and Carmelita invited their family to join them during their stay. Three generations of family members traveled from all across the Eastern United States, including Kentucky, Florida, Georgia and Ohio to spend a week with Charlie and Carmelita.
A very close-knit bunch, the family enjoyed a dinner show at Lumberjack Feud where the kids were invited up on stage and given a piece of the log from the lumberjacks, they rode go karts, visited the Ripley's Aquarium in Gatlinburg, and most importantly–they spent time with one another.
Many of the attractions that the family visited can be found on our Smoky Mountain Adventure Pass that gives guests free tickets to several Gatlinburg and Pigeon Forge attractions.
Like many visitors to the Smoky Mountains, Charlie and Carmelita have already started planning their next trip to the area. Having survived such a stressful year that many couples could not even imagine, the two have decided they want to renew their vows in their very own Smoky Mountain wedding.
With a big smile on her face, Carmelita talked about her excitement to put on a white wedding dress, see Charlie in a tux and put a wedding band on her husband's new hand. Charlie's wedding ring was lost in the accident.
Since his accident, Charlie has continued to tell his story at many local venues near his home. He hopes that his story will inspire others whose lives have been affected by similar tragedies.
The couple is also looking forward to their follow-up appearance on The Doctors.
How Charlie and Carmelita Met
Carmelita was 16 when she met Charlie. He was a couple years older than she was, but they were high school sweethearts.
"He was my first boyfriend," said Carmelita as she smiled and turned to look at Charlie.
However, it wasn't happy ever after quite yet for the young couple. Like most high school romances, they eventually went their separate ways. Years later, not knowing the couples past, a mutual friend set Charlie and Carmelita up on a blind date.
Today, nearly two decades later, they are still very much in love.
Do you have your own story of love that lead you and your family to the Smoky Mountains? Let us know about it on our Facebook page!
Also, if you want to experience a few of the fun and exciting things that Charlie, Carmelita and their family were able to during their Smoky Mountain vacation, begin planning your next trip with us today by giving us a call at (877) 369-9694.
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Twenty-four Year 8 students participated in the launch of the Go4SET Project, hosted by EDT at Leeds Beckett University on Wednesday 30th January 2019.
This is a project that incorporates the STE(A)M subjects and sees students working together to investigate real industrial issues and develop innovative solutions.
We are excited to see their plans and projects develop over the coming months.


text:
* qc.Pointer getPointer(id);

## Paramters
| Paramter | Type | Description |
| --- | ---- | ---- |
| id | number | Device Id, see: [qc.Mouse](Mouse.md) and [qc.Touch](Touch.md) |

## Description
Get pointer by id.

redpajama_set_name: RedPajamaGithub


text:
Q: Why map.collectEntries() not working for this data [[Name:sub, Value:23234]] - Groovy Why this works:
def m =  [[1,11], [2,22], [3,33]]
println(m.collectEntries())

output: [1:11, 2:22, 3:33]
But this doesn't work:
def m = [[Name:sub, Value:23234], [Name:zoneinfo, Value:Europe/London]]

println(m.collectEntries())

output:
groovy.lang.MissingPropertyException: No such property: sub for class
I want to process that map so that I get a list of key value pairs like this:
["Name:sub" :"Value:23234", "Name:zoneinfo": "Value:Europe/London"]
where Name:sub is the key and Value:23234 is the value.
Reference https://stackoverflow.com/a/34899177/9992516

A: In the second example sub and zoneinfo are being read as variable names, not strings, and you need to quote them.
def m = [[Name:'sub', Value:23234], [Name:'zoneinfo', Value:'Europe/London']]
println m.collectEntries{ ["Name:${it.Name}", "Value:${it.Value}"] }

A: It cannot find sub field in your class, probably you want to have a string "sub"?
Basically, map entry can be declared in two ways:
Name: 'sub'

and
'Name': 'sub'

For the key it is assumed that is is a String, even if it is not wrapped by quotes.
But for the value it is mandatory to wrap in quotes. Otherwise, it is treated as a variable (or field)

A: Given your desired results:
["Name:sub" :"Value:23234", "Name:zoneinfo": "Value:Europe/London"]

What you actually need to do is quote the entire item in each pair:
def m = [["Name:sub", "Value:23234"], ["Name:zoneinfo", "Value:Europe/London"]]

redpajama_set_name: RedPajamaStackExchange


[Essence] Advanced Snail 96 Mucin Power Essence for intense hydration! Made with all-natural domestic 96% snail secretion filtrate, the Advanced Snail 96 Mucin Power Essence is a Real Power Essence that transform the skin while keeping in the moisture and encouraging the real power of skin in a healthy way. It replenishes nutrients to the skin to prevent and repair damages and fills the skin with elasticity for a healthier, younger looking skin.By gently removing overnight build-up of sebum and dead skin cells, the Low pH Good Morning Gel Cleanser helps you get a refreshing start on your day without all the fuss. So say "Good morning, beautiful !" and start your day fresh with the Low pH Good Morning Gel Cleanser.
[Cream] Advanced Snail 92 All In One Cream for anti-aging with maximum hydration! Made with all-natural domestic 92% snail secretion filtrate, the Advanced Snail 92 All In One Cream acts to prevent aging and promote a healthy, rejuvenated skin while keeping in the hydration of a snail cream. Safe to use on any and all kinds of skin due to its nature of only natural, excellent ingredients, the Advanced Snail 92 All In One Cream is another COSRX MUST HAVE !
[Essence] Full of skin nutrients for healthier, stronger skin, Rejuvenation with anti-wrinkle effects, Complete hydration without the irritation.
[Cream] Full of collagen to maintain healthy, wrinkle-free skin, Snail cream that preserves youth & prevents aging, Anti-aging rejuvenation & maintenance, Complete hydration without the irritation.
[Essence] 1) Apply only a light amount to the forehead and nose areas. 2) Gently massage in plenty of the essence to the cheek area until fully absorbed. 3) For the under eye area, lightly tap like you're playing piano to help the skin absorb the the product.
[Cream] 1) After cleansing, at the last step of your basic care, apply an adequate amount to the face, dividing up the portions and applying each small portion to different areas. Lightly tap the area to help absorption. 2) Gently massage the whole face using your palms about 2-3 times to ensure full absorption.


Have you ever considered your dog's paws? Whenever a baritone saxophone, or tuba for that matter, is introduced into an improvising scene, I think about my dog's forepaws. While you have hands with fingers designed for intricate work attached to your arms, a dog has these blunt clubs. I always considered the baritone saxophone to be in the same blunt category. That is, until I was introduced to the music of Colin Stetson, Mats Gustafsson and now g a b b r o, a two baritone saxophone duo of Hanne De Backer and Marc De Maeseneer. De Maeseneer is a member of the trio Backback, who released III (El Negocito Records, 2014).
The pair elevates the bari from an unsharpened tool to a refined instrument. Opening with the familiar boat-horn blasts on "Sterna Paradisaea," the pair then weave a nuanced sound through their two voices. "For The Souls Of Nauru" has one horn gliding over the resonating minimalist breath of the other, then upper register soundings engage with the flutter notes. Now, we're miles away from boat horns and bottoms. "Minor Swing" impresses with a circular breathing saxophone pulse matched by a haunting refrain. Elsewhere, the pair fashion a minimalist tome on "We've Seen Life On Mars!?," with sounds that are as impenetrable and desolate as any deep space explorer can imagine. "Kraveel Bos" pairs a melody against pulse, culminating in what could be an operatic vision. Impressive music making here, and it makes me question just how my dog opened the front door last week.
Track Listing: Sterna Paradisaea; 821 DARK; For The Souls Of Nauru; Minor Swing; We've Seen Life On Mars!?; Kraveel Bos; Hellh Olé.
Personnel: Hanne De Backer: baritone saxophone; Marc De Maeseneer: baritone saxophone.


This breathable padding can be worn under compression bandages for added comfort and an even distribution of compression. Skin-friendly and reusable!
Rosidal soft is perfectly suited for padding underneath compression bandages. It helps evenly distribute the compression and protects the skin. Rosidal Soft is air and moisture permeable, skin friendly, latex free and tear-resistant. Made from polyurethane foam, it will not lose its elasticity even after repeated washing. This property makes it a truly cost-effective padding.
Rosidal soft can also be pulled slightly when applied to provide some compression and shaping of the limb.
Roll length is 8.2 feet.


text:
ACTS & FACTS IMPACT RADIOMETRIC DATING
Both Argon and Helium Diffusion Rates Indicate a Young Earth
BY LARRY VARDIMAN, PH.D. * |
In the final report of ICR's Radioisotopes and the Age of the Earth (RATE) project, Dr. Russell Humphreys reported that helium diffusion from zircons in borehole GT-2 at Fenton Hill, New Mexico, gave an age for the earth of 6,000 ± 2,000 years.1 This young age agrees with a literal reading of Scripture, but is at variance with the billions of years conventionally held. Gary Loechelt has been a frequent critic of Humphreys' procedures for calculating the young age by helium diffusion.2 Humphreys has responded to Loechelt and other critics, demonstrating that their concerns were invalid and successfully defending his findings.
However, due to Loechelt's persistent criticisms, Humphreys recently took a deeper look at one of the key papers on which his helium diffusion research was based, and he found some rather odd assumptions about local heating near the borehole.3 He concluded that some of the assumptions about the heating history of the borehole were made to avoid problems the authors of the paper (Harrison et al4) would otherwise have had with the diffusion of argon from the sample.
Humphreys decided to develop a second, independent method for estimating the age of the earth based on the diffusion of argon from feldspar in the same Fenton Hill borehole. The result was a slightly younger age for the earth than his earlier helium diffusion method.
A Brief Review of Diffusion
When radioactive isotopes decay in rock, various gases are produced as a byproduct. For example, uranium-238 in the rock decays to lead by alpha decay, producing alpha particles that combine with electrons to form helium. Potassium-40 decays directly to argon-40 by inverse beta decay and electron capture. The gases produced by radioactive decay are then free to move through the minerals in which they are imbedded and escape into the atmosphere.
However, the rate at which the gases can escape is highly dependent on the temperature of the minerals. For example, the rate of helium diffusion at the hot temperatures 15,000 feet below the surface is about 160 times faster than the rate at the cooler temperatures at 4,000 feet. Consequently, rock deep in the crust of the earth will be more depleted in helium than rock near the surface.
Humphreys was able to calculate the diffusivity, a measure of the rate of escape of helium from the zircons in the granite at Fenton Hill. Figure 1 displays observed and theoretical diffusivities for helium as a function of temperature. Note that temperature in degrees Celsius is hotter on the left side of the figure, so the diffusivity increases upward to the left. The diffusivity is plotted on a logarithmic scale and increases by a factor of 10 for each tick on the vertical axis.
There are five white data points shown on the red and green curves in the lower right portion of the figure. These are actual concentrations of helium measured from the Fenton Hill core used to compute diffusivity. The diffusivity for the red curve (the uniformitarian model) was computed by dividing the difference between the theoretical amount of helium produced over the conventional age of the rock and the measured amount remaining by the conventional 1.5-billion-year age of the rock.
The diffusivity for the green curve (the creation model) was computed by dividing the difference in helium concentration by 6,000 years. Note there is a factor of about 100,000 in diffusivity between the two curves. In other words, the rate at which helium diffuses from the rock must be many times slower for the uniformitarian model in order to explain the concentration of helium observed in the rock today.
The RATE project obtained samples of granite from the Fenton Hill borehole and submitted them to one of the most widely respected helium laboratories for determination of helium diffusion rate as a function of temperature. Humphreys hypothesized before the laboratory work was completed that the results would fit the creation model rather than the uniformitarian model and support a young earth.5 Figure 1 clearly shows that his hypothesis was confirmed. The blue data from the laboratory experiments matched the green curve so well that Humphreys has said several times in his public lectures, "Never in my entire scientific career have I ever seen a numerical prediction verified so accurately." Using the laboratory-measured diffusion rates, he was able to compute an estimated age of the earth and its uncertainties. The value was 6,000 ± 2,000 years.
The New Argon Results
The deep Precambrian granite "basement" rock from the Fenton Hill GT-2 borehole contained not only zircons from which helium diffusion rates could be determined, but also a potassium-bearing microcline feldspar containing argon-40 that could be used to estimate age. Harrison et al conducted argon-argon dating and diffusivity measurements on five feldspar samples.4 They were forced to assume recent heating of the rock in the borehole from a nearby volcano to explain the abundant release of argon evident in the samples.
They rejected several of the samples from their full analysis because the diffusion rates resulted in a young earth. However, they reported the laboratory results on all five samples. Figure 2 shows their "Age Spectrum" for one of their rejected samples (sample 5) collected from the hottest temperature at a depth of 15,000 feet below the surface. It shows the conventional estimate for age as a function of the percent of argon released by heating experiments in the laboratory.
The peak of 1160 Ma in Figure 2 shows that over "one billion years' worth" of potassium-40 to argon-40 decay occurred in situ. RATE hypothesized that this decay occurred during several episodes of accelerated nuclear decay in the past, the more recent during the year of the Genesis Flood.
RATE also hypothesized an accelerated cooling mechanism that would have gotten rid of much of the resulting radiogenic heat. Harrison et al had more confidence in the estimate of losses of argon in sample 5. Humphreys also believed that the age of sample 5, with a small adjustment in the percentage of argon loss, was more accurate and better-founded than the others.
Humphreys used the argon data from Figure 2 to compute the age of sample 5 to be 5,100+3,800 -2,100 years, where 5,100 years was his best estimate with the lowest age of 3,000 years and the oldest age of 8,900 years. Humphreys' lower estimate of 3,000 years was the same as the estimate made by Harrison et al.4
Humphreys concluded that the observed high argon retentions shown in Figure 2 conflict severely with the uniformitarian-assumed long ages. These data say that the feldspar in the Fenton Hill borehole generated over a billion years' worth of argon-40 and then retained it during a period of time that began only thousands of years ago.The argon data thus support accelerated nuclear decay, RATE's young helium age, and the biblical youth of the world. Consequently, we can say that both argon and helium diffusion rates agree that the earth is only thousands of years old.
Humphreys, D. R. 2005. Young Helium Diffusion Age of Zircons Supports Accelerated Nuclear Decay. In Radioisotopes and the Age of the Earth: Results of a Young-Earth Creationist Research Initiative. Vardiman, L., A. A. Snelling and E. F. Chaffin, eds. El Cajon, CA: Institute for Creation Research, and Chino Valley, AZ: Creation Research Society, 25-100.
Loechelt, G. H. 2010. Critics of helium evidence for a young world now seem silent? Journal of Creation. 24 (3): 34-38.
Humphreys, D. R. 2011. Argon diffusion data support RATE's 6,000-year helium age of the earth. Journal of Creation. 25 (2): 74-77.
Harrison, T. M., P. Morgan and D. D. Blackwell. 1986. Constraints on the age of heating at the Fenton Hill site, Valles Caldera, New Mexico. Journal of Geophysical Research. 91 (B2): 1899-1908.
Humphreys, D. R. 2000. Accelerated Nuclear Decay: A Viable Hypothesis? In Radioisotopes and the Age of the Earth: A Young-Earth Creationist Research Initiative. Vardiman, L., A. A. Snelling and E. F. Chaffin, eds. El Cajon, CA: Institute for Creation Research, and Chino Valley, AZ: Creation Research Society, 333-379.
* Dr. Vardiman is Senior Research Scientist, Astro/Geophysics at the Institute for Creation Research.
Cite this article: Vardiman, L. 2011. Both Argon and Helium Diffusion Rates Indicate a Young Earth. Acts & Facts. 40 (8): 12-13.

redpajama_set_name: RedPajamaCommonCrawl


text:
Jun 4, 2014 | Evenings Weddings Festive & Formal
On the evening of June 8th, Broadway's elite will come together at New York's fabled Radio City Music Hall to celebrate the 68th Annual Tony Awards. The American Theatre Wing's Tony Awards are presented by Tony Award Productions, a joint venture of The Broadway League and the American Theatre Wing. The two organizations have jointly administered the Tony's since 1967, the year of the very first Tony telecast. We will be watching especially closely as our brilliant actress intern, Ginna LeVine, will be in the audience. This year the ever-dreamy Hugh Jackman will be hosting the spectacular event.
For what to wear to a glamorous awards show, the brilliant pink Monique Lhuillier get's a rave review. The flattering strapless neckline will looking dazzling as you take to your seat, and just incase your name is called, looks how wonderful you will look from behind as you ascend to the stage. Accessories are equally chic as they play off the shade and the style of the gown. And with the lovely trumpet hemline, you can walk the red carpet with confidence.
For more information and to purchase, please click the links. ML Monique Lhuillier Strapless Evening Gown $598 / Kate Spade New York Mini Bouquet Linear Drop Earrings $78 / Kate Spade Seaview Fringe Collar Necklace $248 / Jimmy Choo Cayla Glitter Clutch $1195 / Jimmy Choo Ivette Crinkled Leather Sandals $795
2014 Tony Awards Nominations Ceremony You can see the full list on the Tony Website. Leading the pack with 10 nominations is A Gentleman's Guide to Love and Murder. The second-highest total went to the Neil Patrick Harris starring revival of "Hedwig and the Angry Inch," with eight nominations, including best revival of a musical. As previously reported, the 2014 Special Tony Award for Lifetime Achievement in the Theater will be presented to costume designer Jane Greenwood. If you can't make it to Radio City on June 8th, be sure to tune into CBS-TV to watch from home!


United Grinding's new MÄGERLE MFP 51 combines grinding with conventional machining operations within one machining system. This flexible machine features either 5 or 6 axes for grinding, milling and drilling operations to process parts in single clamping for improved production quantity and quality. It includes a high-precision 12,000-rpm spindle, as well as an integrated 66-position tool changer for efficiency with multiple workpieces eliminating the need for complete tooling changes. The machine's coolant nozzle features 2-axis control for more movement and accurate positioning of coolant delivery to the tool and workpiece. MÄGERLE MFP 51 features an overhead grinding wheel dresser that is integrated into the machine's grinding support to shorten the overall process time. Other options available on this machine include an RFID-based identification system for grinding wheels and tools to eliminate data input errors.
MIAMISBURG, Ohio, August 15, 2018 – UNITED GRINDING will present, for the first time in North America at IMTS in booth 236802, the MÄGERLE MFP 51 that combines grinding with conventional machining operations within one production system. This flexible machine comes equipped with either 5 or 6 axes for grinding, milling and drilling operations to process parts in single clampings for improved accuracy and output.
In its standard configuration, the MÄGERLE MFP 51 includes a high-precision 12,000-rpm spindle and an integrated 66-position tool changer for efficient machining of multiple workpieces without the need for complete tooling changes. The machine's coolant nozzle features 2-axis control for full freedom of movement and precise positioning of coolant delivery to the tool and/or workpiece. Through-the-spindle coolant delivery, along with nozzles on the grinding support, optimize coolant delivery. An optional nozzle changer allows for further adaptation of the coolant supply delivery to individual jobs.
An overhead grinding wheel dresser on the MÄGERLE MFP 51 is integrated into the machine's grinding support to shorten process times. Options include an RFID-based identification system for grinding wheels and tools to eliminate errors when entering tool data in the machine.
For UNITED GRINDING, the MÄGERLE MFP 51 represents one of five new machines slated for their North American unveiling at IMTS 2018. UNITED GRINDING will also feature the BLOHM PROFIMAT XT grinding machine, STUDER favorit universal machine, STUDER WireDress® machine-integrated dressing technology for metal-bonded grinding wheels, WALTER HELITRONIC POWER DIAMOND 400 "two-in-one" eroding and grinding machine and a production version of the flexLoad automation system integrated with a MIKROSA KRONOS S 250 centerless cylindrical grinding machine.
United Grinding North America Inc., a subsidiary of the UNITED GRINDING Group, represents a union of some of the world's strongest companies in grinding and ultra-precision finishing solutions for the manufacturing industry. Through its surface and profile grinding, cylindrical grinding and tool grinding technology groups, the company sells and supports precision machines for grinding, eroding, laser ablation, combination machining and measuring under the MÄGERLE, BLOHM, JUNG, STUDER, SCHAUDT, MIKROSA, WALTER and EWAG brands. Headquartered in Miamisburg, Ohio, UNITED GRINDING North America is ISO 9001 certified to ensure quality in product development, production, shipping and support operations. Learn more at grinding.com.
Tool Grinder uses 20 hp direct drive 5,800 rpm spindle.
Burr/Cutting-Tool Grinder provides turnkey solution.


text:
[NotiAMCA] USNCCM12 Abstract Submission Deadline Extended
Dom Feb 17 21:39:35 ART 2013
Mensaje anterior: [NotiAMCA] Final Call for Papers - Civil-Comp Conferences - Sardinia Sept 2013
Próximo mensaje: [NotiAMCA] Charlas "De la Ciencia a la Tecnología"
Dear Colleagues: The deadline to submit an abstract to the 12th U.S. National Congress on Computational Mechanics has been extended to February 28, 2013. Please note that there will not be further extensions after the new due date. We encourage you to submit
your abstract as soon as possible and look forward to seeing you at the Congress. The review of submitted abstracts will begin on February 18, 2013. To submit your abstract, please go to
http://12.usnccm.org/abstract-submissions and click "submit abstract" at the bottom of the page. Please select MS 5.3 as the minisymposium before submitting your abstract. Important Dates:        February 28, 2013: Deadline for abstract submissions        March 15, 2013: Notification of final abstract acceptance/rejection        March 1-31, 2013: Travel award applications accepted        March 15 - May 15, 2013: Early registration        April 15, 2013: Travel awards announced        May 16 - June 30, 2013: Regular registration period        After July 1, 2013: Late/onsite registration only        July 22-25, 2013, Congress dates Please feel free to forward this announcement to interested colleagues. For more information, please visit the congress website at
http://12.usnccm.org/. If you have questions, feel free to contact us. Sincerely, Howie Fang  (The University of North Carolina, Charlotte, USA,
hfang en uncc.edu)Guilin Wen  (Hunan University, Changsha, China,
wenguilin en yahoo.com.cn)David C. Weggel  (The University of North Carolina, Charlotte, USA,
dcweggel en uncc.edu)Qing Li  (The University of Sydney, Sydney, Australia,
Q.Li en usyd.edu.au) ___________________________________________________ Howie Fang, Ph.D., Associate ProfessorDepartment of Mechanical Engineering & Engineering ScienceImpact and Structural Optimization Laboratory (ISOL)The University of North Carolina at Charlotte9201 University City Blvd., Charlotte, NC 28223-0001 Phone: (704) 687-8328  |  Fax: (704) 687-8345Email:
hfang en uncc.edu  |  URL:
http://coefs.uncc.edu/hfang/___________________________________________________ From: USNCCM12 [mailto:info en usacm.org]
Sent: Thursday, February 14, 2013 4:18 PM
Subject: USNCCM12 Abstract Submission Deadline Extended Dear USACM Member:
Due to several requests, the deadline to submit an abstract to the 12th U.S. National Congress on Computational Mechanics, to be held in Raleigh, NC, July 22-25, 2013, has been extended to
February 28, 2013.  We strongly urge you to submit your abstract as soon as possible as we will not be able to extend the deadline beyond this date.
For instructions on how to submit your abstract, go to: http://12.usnccm.org/abstract-submission.
We look forward to seeing you as USNCCM12.
USNCCM12 Organizers
URL: <http://venus.santafe-conicet.gov.ar/pipermail/notiamca/attachments/20130217/0332b82b/attachment.html>


text:
Acalypha gracilens (Slender Three-Seeded Mercury) on 10-24-21, #851-1.
Slender Three-Seeded Mercury. Three-Seeded Mercury, Shortstalk Copperleaf, Slender Copperleaf
Acalypha gracilens
ak-uh-LY-fuh grass-il-ENS
Synonyms of Acalypha gracilens (11) (Updated on 12-21-22 from Plants of the World Online): Acalypha gracilens var. delzii L.W.Mill. (1969), Acalypha gracilens var. fraseri (Müll.Arg.) Weath. (1927), Acalypha virginica Michx. (1803)(nom. illeg.), Acalypha virginica var. fraseri Müll.Arg. (1865), Acalypha virginica var. gracilens (A.Gray) Riddell (1853), Acalypha virginica var. gracilescens Müll.Arg. (1865), Acalypha virginica var. intermedia Riddell (1853), Acalypha virginica var. ovalifolia Riddell (1853), Acalypha virginica var. ramosa Riddell (1853), Acalypha virginica var. rhombifolia Riddell (1853), Acalypha virginica var. texana Riddell (1853)
Acalypha gracilens A.Gray is the accepted scientific name for this species. The species was named and described by Asa Gray in A Manual of the Botany of the Northern United States in 1848.
The genus, Acalypha L., was named and described by Carl von Linnaeus in the second volume of the first edition of Species Plantarum in 1753.
As of 12-21-22 when this page was last updated, Plants of the World Online lists 436 species in the Acalypha genus. It is a member of the plant family Euphorbiaceae with 227 genera. Those numbers could change as updates are made on POWO.
Distribution map of Acalypha gracilens from Plants of the World Online. Facilitated by the Royal Botanic Gardens, Kew. Published on the Internet; http://www.plantsoftheworldonline.org/. Retrieved on December 21, 2022.
The above distribution map for Acalypha gracilens is from Plants of the World Online. Areas in green are where the species is native and purple is where it has been introduced. The map on the USDA Plants Database is similar.
The map on iNaturalist shows where members have made observations. Anyone can join and it is a great website to confirm and share your observations. The maps on iNaturalist are continually updated as members post new observations.
THERE ARE SEVERAL LINKS AT THE BOTTOM OF THE PAGE FOR FURTHER READING AND TO HELP WITH A POSITIVE ID.
As I was walking through the main hayfield on October 24 in 2021, I spotted this interesting plant with glowing coppery leaves. I took photos and identified the plant on iNaturalist as Acalypha gracilens. Normally, I don't do any wildflower hunting after mid-October because we usually have a few frosts by then and there isn't much going on. Common names for this species are Slender Three-Seeded Mercury. Three-Seeded Mercury, Shortstalk Copperleaf, Slender Copperleaf, and perhaps others.
Acalypha gracilens is a monoecious annual wildflower with deep taproots. It prefers open areas in forests, rocky prairies, low meadows, and roadsides. I found a few of these plants growing on the hill in the hayfield. The genus name, Acalypha, is a Greek word that refers to the nettle-like shape of its leaves. The species name, gracilens, is a Latin word that means slender or graceful.
A lot of the descriptions of plant anatomy are somewhat complicated to understand and you need a glossary. I will attempt to describe it the best I can in layman's terms…
This species grows either from a single stem or branches from the base growing to around 15 to 30" in height. The stems can be green or reddish-brown and have short, appressed hairs.
Acalypha gracilens (Slender Three-Seeded Mercury) at 4 1/4″ tall on 10-25-21, #852-1.
I went back the next day to get more photos of this plant and couldn't find the same one. Luckily, I found a few more.
The leaves grow in an alternate pattern along the stems, one leaf per node, and have short hairs that are turned inward facing the stem (antrorse pubescent). The leaves are fairly slender, lance-shaped, and taper to a point. They have two prominent lateral veins that run parallel to the midrib. Leaves are kind of dull green that turn a copper color in the fall.
The inflorescence (flower stem), 8-9 mm long, has male (staminate) and female (pistillate) flowers. The female flowers are lower on the raceme while the male flowers are toward the tip. Female flowers are surrounded by toothed bracts with 3-5 teeth that are said to be antrorse pubescent (small hairs that point toward the stem)… The flowers are more obvious after flowering from May through October.
They produce 3-seeded fruit that are dispersed by explosive mechanisms that are possibly triggered by ants…
Distribution map for Acalypha gracilens in Missouri from the USDA Plants Database. Published on the internet at https://plants.sc.egov.usda.gov/home. Retrieved on December 30, 2021.
Hmmm… According to the Missouri Plants website, Acalypha gracilens is found mainly in the southeastern and east-central part of Missouri. Zooming in on the USDA map for Missouri, it shows the species growing in a few counties scattered in the northern part and along the east and southeast part of the state. It seems the species has found its way to Pettis County where I live in the west-central part of the state. BONAP (The Biota of North America Program) shows it is present in every county in Missouri… Well, no map is perfect… All I know is that I found a few plants on the hill in the main hayfield/pasture in October in 2021…
NOW, it could be a similar species such as Acalypha monococca (One-Seeded Mercury) or Acalypha virginica (Virginia Copperleaf/Virginia Three-Seeded Mercury). I took photos of one plant that was identified as Acalypha virginica in 2022 on iNaturalist (Research Grade), but there wasn't really any identifying features to prove that. It was growing along the old foundation (where my grandparent's old home was) with a colony of Euphorbia dentata. So, I really need to find plants and take detailed photos to make a proper identification. Both Acalypha gracilens and A. virginica produce 3 seeds while A. monococca produce only one. A. gracilens and A. virginica are even more similar, but the "hairs" on the stems are different. A. virginica has hairs that are more appressed and spreading. I would note that one of the common names for A. monococca (the one used by iNaturalist) is Slender Three-Seeded Mercury. That is odd since that species only produces one seed… I flagged the species and explained A. monococca had only one seed, so they changed the common name to Three-Seeded Mercury. The seeds on all three species look somewhat different, so I think the seed, types of hairs on the stem, and shape of the leaves are key features to look at… HOPEFULLY, in 2023 I can figure out which species are here on the farm for sure. You never know where they will pop up which could prove to be quite interesting.
As far as using maps go, the USDA Plants Database shows Acalypha gracilens is not present in Pettis County (where I live) or surrounding counties. BONAP just says it is present in the state without county data. BONAP and USDA both show A. monococca as being present in the county I live in and most of Missouri. The USDA map does not show Pettis for A. virginica but shows it present in surrounding counties. BONAP shows it present in Pettis and most of Missouri. Hmmm… The USDA gets its data from BONAP… The date on the BONAP maps is 2014… A LOT can change in 10 years. Let's face it, data is based a lot on specimens collected and pressed many years ago and not current findings. The maps on iNaturalist are based on observations by its members and are continually updated. But, not many members have posted observations for these three species of Acalypha. My observation of A. gracilens was not agreed on, so it didn't become Research Grade. Someone, however, did agree on my observation of A. virginica, but personally, I can't tell by my photos how a positive ID could be made. It was windy and I could get good close-ups. Practice makes perfect… Controversial species are hard to get someone to agree which I why I normally take A LOT of photos.
So, the goal in 2023 is to find more Acalypha on the farm and take as detailed photos as I possibly can. Especially of the fruit and hairs on the stems… I have likely passed over them many times because it's the flowers that always catch my eye. Flowers of these three species are definitely not eye-catching…
I have enjoyed photographing and learning about the many wildflowers growing on the farm and other areas nearby. I live on a small farm in Windsor, Missouri in Pettis County (Henry County is across the street, and Benton and Johnson aren't far away). I have grown over 500 different plants and identified over 200 species of wildflowers (most have pages listed on the right side of the page). I am not an expert, botanist, or horticulturalist. I just like growing, photographing, and writing about my experience. I rely on several websites for ID and a few horticulturalists I contact if I cannot figure them out. Wildflowers can be somewhat variable from location to location, so sometimes it gets a bit confusing. If you see I have made an error, please let me know so I can correct what I have written.
I hope you found this page useful and be sure to check the links below for more information. They were written by experts and provide much more information. Some sites may not be up-to-date but they are always a work in progress. If you can, I would appreciate it if you would click on the "Like" below and leave a comment. It helps us bloggers stay motivated. You can also send an email to me at thebelmontrooster@yahoo.com. I would enjoy hearing from you especially if you notice something is a bit whacky.
PLANTS OF THE WORLD ONLINE (GENUS/SPECIES)
INTERNATIONAL PLANT NAMES INDEX (GENUS/SPECIES)
TROPICOS (GENUS/SPECIES)
FLORA OF NORTH AMERICA (GENUS/SPECIES)
WORLD FLORA ONLINE (GENUS/SPECIES)
WIKIPEDIA (GENUS/SPECIES)
USDA PLANTS DATABASE
MISSOURI PLANTS
WILDFLOWER SEARCH
LADY BIRD JOHNSON WILDFLOWER CENTER
MARYLAND BIODIVERSITY PROJECT
NOTE: The data (figures, maps, accepted names, etc.) may not match on these websites. It depends on when and how they make updates and when their sources make updates. Some websites have hundreds and even many thousands of species to keep up with. Accepted scientific names change periodically and it can be hard to keep with as well. Some of the links may use a name that is a synonym on other sites. In my opinion, Plants of the World Online by Kew is the most reliable and up-to-date plant database and they make updates on a regular basis. I make updates "at least" once a year and when I write new pages or add new photos but I do get behind. We are all a work in progress. 🙂


Lovely 3 bedroom with two .75 baths rambler and two attached garage. Conveniently located close to shopping, recreation on American Lake and I-5 access. Minutes to Joint Base Lewis-McChord and the VA Hospital. Let your inner creativity shine to update this home.


Microsoft's new Play Anywhere feature allows gamers to access certain titles through cross-platform compatibility. This means being able to play across Xbox One and PC, as well as sharing saves. Well, new info points to Resident Evil 7 possibly having Play Anywhere features.
According to IGN, Resident Evil 7 appeared in a recent article on Dengeki where they discuss each format's features, one of which includes a translation for the game's appearance on the Windows Store, where they revealed that there will be cross-platform compatibility between PC and Xbox One for saved games.
IGN points out that cross-platform saves are one of the key features for the Play Anywhere concept being pushed by Microsoft. It allows gamers to purchase a title digitally on PC or Xbox One and then play it on either platform, with the saved game sharing across both systems. The Play Anywhere also ties into cross-platform multiplayer as well, allowing for some games to enable PC players to play alongside Xbox One gamers.
According to the article, they did receive confirmation that Capcom's Resident Evil 7 would be one of the first third-party titles to make full use of cross-saves from PC to Xbox One or Xbox One to PC. However, what they could not confirm was whether or not cross-buying was an option.
Usually a game that makes use of the Play Anywhere feature also allows for cross-buys, which means that you could buy a Windows Store copy of Resident Evil 7 for PC and then attach it to your GamerTag account and then play it on the Xbox One. It's a feature that Sony has been capitalizing on to great lengths with the PS4 and PS3, as well as the PS3 and PS Vita, and PS4 and PS Vita. The ability to buy a game on one platform and then have access to it on another platform is a huge way to get gamers with multiple platforms to consider buying the game because it's almost considered getting a two-for-one deal.
The thing is, Capcom wouldn't confirm to IGN whether or not cross-buys would be available for Resident Evil 7. So while we know that cross-saves are going to be present, cross-buys may or may not be.
It would be a really odd move to allow Xbox One and PC gamers to share saves between platforms, but then force them to have to buy two different copies of the game to make use of the feature. Most people would likely ignore the game on either platform if the Play Anywhere feature wasn't really going to be utilized to its fullest.
But then again, Capcom may be weighing the options and seeing it as a potential risk to their bottom line if PC gamers just had to purchase one copy of Resident Evil 7 to play it on the Xbox One (or vice versa), as opposed to getting people to buy individual copies for each system. At the end of the day, a customer who pays twice for the game is more important than one who pays once for it.
Of course, Capcom may actually bite the bullet and allow for cross-buys between PC and Xbox One... but they certainly aren't going say so right now. We'll have to wait to find out what deal is with Resident Evil 7 and the Play Anywhere feature.


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Posted by Jill Boniske aka Arty Chick on January 26, 2012
Mixed martial arts (MMA) superstar Gina Carano plays the lead and does all her own stunts in Steven Soderbergh's latest action flick Haywire, which comes off feeling kind of Bourne-lite. In it she is surrounded by a pretty yummy collection of today's high powered male stars: Antonio Banderas, Michael Fassbender, Ewan McGregor, Channing Tatum, even Michael Douglas. And that is the problem with the film. Carano is not an actress, and she really cannot hold her own with the big boys.
The basic story of Haywire is that Mallory is former special forces and now she works for a shady government contractor (Ewan McGregor) doing shady things around the world. She and Tatum are sent to extract a kidnapped Chinese dissident from an apartment in Barcelona, which seems to go just fine. And the next thing you know she is heading to Dublin for a simple job with a British spy played by fully clothed Michael Fassbender. But something went wrong in Barcelona, unbeknownst to Mallory, and before you know it, Mr. British spy is trying to kill her, and she is on the run from everyone on earth. The rest of the film is Mallory running around, fighting with various evil people, and trying to hunt down the various men (there are no other women in this world) who set her up. There is A LOT of fighting, which is good because when she is attempting to act, it falls flatter than flat.
The plot is a convoluted, and I get pretty tired of watching a woman get knocked around by men, even if she can take care of herself and ends up dispatching them one by one. Haywire will certainly not go down as one of Soderbergh's hits. It isn't a total miss, but it could use the some of the intelligent plotting of Traffic, or some of the wit of Ocean's Eleven. Mostly it suffers from the lack of a female star who could make you care that everyone is trying to killer her. I'd say wait to watch this one on an airplane.
Other Recent Reviews Not to Miss
Review: A Man Called Otto
Review: Whitney Houston: I Wanna Dance With Somebody
Review: Glass Onion: A Knives Out Mystery
Review: Onoda: 10,000 Nights in the Jungle
Reviews: She Said and Women Talking
Adventurous Chick, January 26, 2012:
This movie made me want to do three things: visit Barcelona, visit Dublin, start taking kick-boxing lessons again. It did not, however, make me want to recommend it to anyone. I feel like it would be a fun rental when you are in the mood for some kick-ass action. But I expected more from Soderbergh. The plot is your standard everyone double crossing everyone thriller, nothing special really. The cast is full of big names, but like Arty Chick said, Carano can't really run with the big dogs yet when it comes to the acting. But I do think she has potential. She has quite a screen presence when she's beating the crap out of someone. So who knows? Maybe she can build on that. Definitely in the wait for rental category.
Arty Chick, January 26, 2012:
I think the problem with her is that she has potential as an action hero, but this one needed an actress. Her delivery was pretty much one note, which works fine for a kick-ass, killing machine, just not for a lead character.


This morning Pr André will preach from Ezekiel 36:22-27 and Matthew 6:9-13 on the theme "Hallowed Be Your Name." God is absolutely holy - the angels around His throne constantly cry "Holy, holy, holy!" What do we then mean when we pray "Let Your Name be made holy"? Can we make God more holy or less holy? Of course not! So why does Jesus teach his disciples, and by implication us, to pray this way? Come and discover why and how this challenges all who call themselves Christian.


Don't Just Diet - Page 2 of 2 - Learn how to achieve a healthy body- for life!
Learn how to achieve a healthy body- for life!
Causes: Why do diets fail?
Obesity is still on the rise, particularly in our children. Unfortunately, most diets don't work. In fact, of the obese people who successfully lose weight, over 95% of them put the weight back on. Why? Don't Just Diet will cut through the ridiculous mess of [mis]information out there and discuss why diets fail and what can be done to lose weight and keep it off.
1. Biologically speaking, we are designed to get fat in today's food environment.
Evolutionarily, humans had the best chance for survival if they ate and stored as many calories as possible when calorically dense foods were available in order to survive periods of famine. This is a large part of the reason that, for most of us, pizza is more hedonically pleasing (delicious) than brussels sprouts- it is a survival advantage to prefer pizza.
Problem is, in most industrialized nations, calorically dense food is always available and famine is rare.
2. Biology changes when a person is severely obese for a long period of time.
The body and brain both act as if the person needs to be at that weight to survive. For example, the number and size of fat cells both increase with obesity. With weight loss diet, fat cell size decreases but fat cell numbers never decrease.
Human biology is a powerful thing and difficult to overcome. Conventional dieting pits efforts to resist temptation directly against human biology- a losing proposition 9 out of 10 times. Don't Just Diet will get to what can and should be done to change this. Stay tuned, I look forward to speaking with you again.
Looking for a minimal effort way to live longer and better? New study shows that fish high in Omega-3 fatty acids really are THAT good for you.
What exactly are Omega-3s? Omega-3's are an unsaturated fatty acid. Unsaturated fats are the good fats (as opposed to trans fats and most saturated fats, which are bad). Unsaturated fats raise your HDL (good) cholesterol, which helps your clear the bad fats and LDL (bad) cholesterol from your body. This helps prevent those precious arteries from getting clogged up- that's why our cholesterol ratio (HDL:LDL) is actually more important than total cholesterol.
Older individuals with higher levels of Omega-3 fatty acids had over a 25% reduced risk of death and lived an average of 2.2 years longer than individuals with low levels of Omega-3s!
The largest benefit was at low levels, so that means that if you're eating NO fish, start eating a LITTLE fish for a BIG benefit!! If you don't like fish, find a good supplement high in the Omega-3s DHA & EPA.
Fish highest in the most beneficial Omega-3s (DHA & EPA): herring, mackerel, lake trout, wild salmon and albacore tuna.
Informative: Arsenic in Apple Juice?
Quick background on organic vs. inorganic arsenic: Organic arsenic is naturally occurring, almost unavoidable and relatively safe. Inorganic arsenic, however, is quite dangerous- it's the same chemical contained in pesticides and is associated with skin lesions, developmental problems, CVD, diabetes and even cancer. So the new regulations are for inorganic arsenic.
New level is 10 parts per billion, which is the same standard for drinking water.
Consumer groups doing a good thing by pressuring the FDA to pay close attention to inorganic arsenic levels in food. However, concern about arsenic in apple juice is actually a little bit of a red herring. Regulating dangerous chemicals is always a good thing but the vast majority of apple juices on the market contain levels well below even the new standard, which means below that in drinking water and even in most cases, what's found in bottled water.
So for me, I don't limit intake of apple juice. What I am concerned about and where I do limit intake, however, is in rice and rice products, particularly brown rice from the southern central US. Just for frame of reference, last year Consumer Reports tested 88 samples of apple juice and the average total arsenic was right around 5 ppb (standard for bottled water). Later that year, they tested rice and rice products and found total arsenic in the hundreds (up to > 900 ppb) in only ¼ cup of rice and the average was more than half of total arsenic was inorganic. If you do the math, it shouldn't take long to realize that this is a MAJOR problem! Thus, worrying about the arsenic in apple juice is like worrying about the fat content of skinless chicken breast and ignoring the 3 lbs of bacon you had a breakfast.
McDonald's French Fries not only unhealthy but not vegetarian!
INGREDIENTS: Potatoes, vegetable oil (canola oil, hydrogenated soybean oil, natural beef flavor [wheat and milk derivatives]*, citric acid [preservative]), dextrose, sodium acid pyrophosphate (to maintain color), salt and dimethylpolysiloxane. The oil used for frying also mentions tertiary butylhydroquinone (TBHQ).
*Natural beef flavor contains hydrolyzed wheat and hydrolyzed milk as starting ingredients.
Some people claim that the beef flavor comes from the milk mentioned above. When was the last time you had a glass of milk that tasted like beef? There is beef extract (contains beef!) and wheat and milk in the beef flavoring added to the fries. They specifically mention the wheat and milk for liability purposes, as these are common allergens.
For decades, McDonald's fries were cooked in beef tallow (beef fat), which gave a slight beef flavor. When they were mandated by the government to switch to vegetable oil, they didn't want to change flavor so they started adding beef flavor (beet extract). They are NOT vegetarian. They had "natural flavor" in ingredient list before being sued in 2001, at which point they added "beef" to the ingredient list. Yes, it's a tiny amount but it is in there.
Otherwise, they contain a smorgasbord of chemicals and preservatives, but who doesn't love a little tertiary butylhydroquinone every now and then? As freaky as it is to know you're consuming silicone and antifoaming agents when you eat fries, the reality is the nutritional value is so dung poor that you're likely to die from diabetes long before the chemicals harm you.
Overall: starch, oil, sugar, preservatives, salt & silicone. Fried. What's not to love?
Informative: Sucralose (Splenda)- Good or Bad?
Nutrition Myths on Informative: Sucralose (Splenda)- Good or Bad?


text:
class LinkList2App
{
    public static void main(String[] args)
    {
        LinkList theList = new LinkList(); // make list
        theList.insertFirst(22, 2.99); // insert 4 items
        theList.insertFirst(44, 4.99);
        theList.insertFirst(66, 6.99);
        theList.insertFirst(88, 8.99);
        theList.displayList(); // display list
    } // end main()
} // end class LinkList2App


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Q: How authenticate IronPDF RenderUrlAsPdf? I'm trying to print out a pdf invoice from a page that requires authentication (https://localhost:44362/invoice). All of this works neatly when authorization is off, but when I turn it on, the whole thing falls apart. I'm using .NET Core 2.1 MVC with Identity authentication. I've tried two different solutions, which both fail different ways.
Attempt 1:
The rendering works, but the login fails, and the resulting pdf is the login page. This, I understand, is normal behaviour when authentication fails.
var uri = new Uri("https://localhost:44362/invoice");
var newPdf = new HtmlToPdf()
{
    PrintOptions = new PdfPrintOptions()
    {
        //..omitted for brevity
    },
    LoginCredentials = new HttpLoginCredentials()
    {
        EnableCookies = true,
        LoginFormPostVariables = new Dictionary<string, string>()
        {
            { "Email", "username@domain.com" },
            { "Password", "secretysecret" }
        },
        LoginFormUrl = new Uri("https://localhost:44362/login")
    }
};
var result = newPdf.RenderUrlAsPdf(uri);

Attempt 2:
I get the authorization cookie from the original request. This works, at least so far that I can actually get the cookie and set it to the LoginCredentials.CustomCookies. I've compared it with the browser request, and the cookie seems to be correct. The collection Request.Cookies holds two cookies, one Antiforgery, and one for Identity.
The rendering fails, because newPdf.RenderUrlAsPdf(uri) returns null and I don't understand why. The reason must be with the CustomCookies set in the LoginCredentials failing somehow, but the stack trace doesn't give any information about what fails. Just to be clear, this method fails even when the authorization is not in use.
var uri = new Uri("https://localhost:44362/invoice");
var cookies = Request.Cookies;
Dictionary<string, string> customCookies = cookies.ToDictionary(c => c.Key, c => c.Value);
var newPdf = new HtmlToPdf()
{
    PrintOptions = new PdfPrintOptions()
    {
        //..omitted for brevity
    },
    LoginCredentials = new HttpLoginCredentials()
    {
        EnableCookies = true,
        CustomCookies = customCookies
        //LoginFormPostVariables = new Dictionary<string, string>()
        //{
        //    { "Email", "username@domain.com" },
        //    { "Password", "secretysecret" }
        //},
        //LoginFormUrl = new Uri("https://localhost:44362/login")
    }
};
var result = newPdf.RenderUrlAsPdf(uri);

A: Because this is the only real search result that comes up when searching for IronPDF authentication/cookie issues, I wanted to add a little info that has taken me WAAAY longer to figure out than I'd care to admit...

*

*This approach of leveraging the custom cookies functionality and using the render url method DOES in fact work.  It will use the copied auth cookie and successfully authenticate to get the markup and any linked resources.  Note that you'll want to use the newer static methods however as the old instance method shown here is legacy/deprecated.

*I was beating my head against the wall assuming the render html method IronPdf.ChromePdfRenderer.StaticRenderHtmlAsPdfAsync worked just like the render url method IronPdf.ChromePdfRenderer.StaticRenderUrlAsPdfAsync.  Sadly, the render html method simply does NOT work this way.  You can set custom cookies all you want, but any requests for linked resources won't be using them.
This is particularly key in an Azure Web App environment where you are leveraging an Identity provider and require authentication for the entire site.  This method of copying the AppServiceAuthSession cookie and using it on IronPDF's Url method call is treated as already authenticated.
It's unfortunate that the IronPDF doc tends to steer you toward the html method as being more reliable when needing to render auth-protected content.  In their defense, the custom cookie doc does explicitly state it's intended for use with the url methods - which makes sense when you think about it - I just kept skimming over that little nugget, and apparently support wasn't aware either.
I'd still prefer to render my view to an html string myself, and use the html method so I'm going to see what support can tell me.  At least now I have an option besides opening up the linked resources to anonymous access.
Edit:
Another little tidbit to watch out for is regarding the use of the HtmlHeader/HtmlFooter properties.  I (stupidly) assumed any markup I added there could easily be styled via a stylesheet and not have to be hardcoded.  It probably can if you don't have to worry about authentication, but otherwise good luck.  The header and footer are literally treated as separate html documents, so if you want the styles applied to them that are applied to your main doc content, there's a property for that - LoadStylesAndCSSFromMainHtmlDocument.  Sadly, this property clearly states it only works for the html methods, not the url methods.  Because I had to use the url methods because of the previously mentioned auth/cookie issues, I was again out of luck.  Then I found the CustomCssUrl property that says it's used to apply the specified stylesheet to the html prior to rendering.  After trying it though, I quickly realized that the calls to this stylesheet apparently don't use the custom cookies, so now we're back to not being able to pull the stylesheet because of authentication.  Ultimately I just hardcoded the styles in the markup I was passing to the HtmlHeader/HtmlFooter because I was starting to question my life choices at this point - LOL.


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Employee Spotlight: Manuel Grajeda
An attitude of wanting to be successful.
That's all it took for Manuel Grajeda, HEVI-Shot, to work his way toward what he has today: two daughters, a wife of 26 years, a relationship with God and a steady job loading ammo at HEVI-Shot where he's an inspiration to his co-workers.
Prior to HEVI-Shot, Manuel had a job working at Dairy Farmers of America – the company that makes Starbucks Frappuccino drinks. But after leaving that job, he and his wife decided to embark on what he now refers to as one of his life's greatest adventures: leaving where he grew up (Oxnard, CA, a city just north of Los Angeles) to live near his mother-in-law in Sweet Home, Oregon.
"Growing up near a big city, I never thought I'd move to this small of a town, but it has been pleasant. It's woodsy out here! There are still some areas locally I haven't even explored. My wife loves the ginormous trees and the changing of leaves. We also appreciate the water… the lakes and rivers," he said.
Manuel started in shipping and receiving at HEVI-Shot 11 years ago but looked for any opportunity to help beyond his job description. From cleaning floors and restrooms to helping loaders grab material, he was a team player looking to be more and do more from day one.
About 7 years ago, he moved to loading, where he works to load 12-guage shells. In his time at HEVI-Shot, Manuel has created a ripple effect, training many employees, advocating for his peers and motivating others to do their best.
"One of the things I've learned is that as long as you're willing to learn and try, you can't go wrong – I still make mistakes, but I have an overall attitude of wanting to be successful. That has gone a long way," he said.
Manuel used an example of a "Top 10 Ammunition Priorities" poster at the plant in Sweet Home, reminding employees of Ammunition's focus areas.
"I read it often, but I've made each listing on that poster a priority for the past 11 years," he said. "It's my hope to get all of us working together on those priorities, so as a company we do better. It's best when everyone works together at it – not rely on just one or two people to do it. That just causes friction."
Perhaps this is where Manuel's leadership style really separates him. He shared servanthood is what he feels is the best way to lead.
"When you choose to be a servant, you take your eyes off yourself and help other people come along," he said. He shared a story of an employee who recently told Manuel he "was to blame" for a recent new challenge she accepted. That employee let Manuel know his positive ideas, thoughts, and encouragement inspired her when she was presented with an opportunity.
"She thought it would be a good thing to step up and not only grow in the company but help other people grow as well. She let me know I inspired her to do so," he said.
Manuel listed several of his life's accomplishments, which included holding a successful job at HEVI-Shot for over 10 years, celebrating 26 years of marriage to his wife and choosing sobriety for nearly 22 years. He attributes much of this success to God – a relationship that has helped him in his marriage, directed him to sobriety, and – perhaps most importantly – led him in a different direction than other family members.
"A person can't help what you're born into. I thank God that my immediate family has not been exposed to some of the things other members of my family were involved in," he said, grateful for choosing a different path.
Thankfully for those who work with him, that path is blazed for others who need a mentor and wish to do better, too.
Last read:
My last read was in the1990s – probably either the "Magic of Thinking Big" by David J. Schwartz or "How to Win Friends and Influence People" by Dale Carnegie. I am a Christian, so most of the time, if I do reading, it's scripture.
Tell us about a secret talent you have.
I'm good at keeping secrets.
Most likely to buy in bulk?
Nah. Not for me. The store is close, and I go get what we need, when we need it.
What would a day off with no obligations look like?
I would relax, watch some old movies. I like the Star Wars episodes.
Favorite Holiday?
Christmas with my family. We do the whole shebang with lights, trees, the whole thing. We have two girls, and we're sure to emphasize the real meaning.
Best concert you've been to?
I'm not a concert person, but when my wife and I were dating, we attended Kenny G in concert.
What does a person need to be happy in your opinion?
I believe that it's really understanding God's love. That has really helped me to be there for my family and also my co-workers. NOT to say there haven't been days that I lose it…
Tell us about an interesting learning point in your life.
In the last 5 years, I've been more involved with local community's city council and school board. I've begun to understand how much control we let our government have over us and how important it is to have people who care about individual rights.
Most interesting job you've had?
I was a private investigator for six months. I look back at that, it was neat. I was able to get information, find a line to draw some conclusions. It was exciting to find things out.
You work loading ammunition. Do you get out to hunt or shoot?
By trade, I fish… but I am not a hunter or shooter. But since working with HEVI-Shot, my wife and I target shoot recreationally. I never thought that I would want to support the Second Amendment right but now I realize how important it is.


text:
// Copyright (c) 2011 Chan Wai Shing
//
// Permission is hereby granted, free of charge, to any person obtaining
// a copy of this software and associated documentation files (the
// "Software"), to deal in the Software without restriction, including
// without limitation the rights to use, copy, modify, merge, publish,
// distribute, sublicense, and/or sell copies of the Software, and to
// permit persons to whom the Software is furnished to do so, subject to
// the following conditions:
//
// The above copyright notice and this permission notice shall be
// included in all copies or substantial portions of the Software.
//
// THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
// EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
// MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
// NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE
// LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION
// OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION
// WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.
package syntaxhighlighter.brush;

import java.util.ArrayList;
import java.util.Arrays;
import java.util.List;
import java.util.regex.Pattern;

/**
 * CSS brush.
 * @author Chan Wai Shing <cws1989@gmail.com>
 */
public class BrushCss extends Brush {

  public BrushCss() {
    super();

    String keywords = "ascent azimuth background-attachment background-color background-image background-position "
            + "background-repeat background baseline bbox border-collapse border-color border-spacing border-style border-top "
            + "border-right border-bottom border-left border-top-color border-right-color border-bottom-color border-left-color "
            + "border-top-style border-right-style border-bottom-style border-left-style border-top-width border-right-width "
            + "border-bottom-width border-left-width border-width border bottom cap-height caption-side centerline clear clip color "
            + "content counter-increment counter-reset cue-after cue-before cue cursor definition-src descent direction display "
            + "elevation empty-cells float font-size-adjust font-family font-size font-stretch font-style font-variant font-weight font "
            + "height left letter-spacing line-height list-style-image list-style-position list-style-type list-style margin-top "
            + "margin-right margin-bottom margin-left margin marker-offset marks mathline max-height max-width min-height min-width orphans "
            + "outline-color outline-style outline-width outline overflow padding-top padding-right padding-bottom padding-left padding page "
            + "page-break-after page-break-before page-break-inside pause pause-after pause-before pitch pitch-range play-during position "
            + "quotes right richness size slope src speak-header speak-numeral speak-punctuation speak speech-rate stemh stemv stress "
            + "table-layout text-align top text-decoration text-indent text-shadow text-transform unicode-bidi unicode-range units-per-em "
            + "vertical-align visibility voice-family volume white-space widows width widths word-spacing x-height z-index";
    String values = "above absolute all always aqua armenian attr aural auto avoid baseline behind below bidi-override black blink block blue bold bolder "
            + "both bottom braille capitalize caption center center-left center-right circle close-quote code collapse compact condensed "
            + "continuous counter counters crop cross crosshair cursive dashed decimal decimal-leading-zero default digits disc dotted double "
            + "embed embossed e-resize expanded extra-condensed extra-expanded fantasy far-left far-right fast faster fixed format fuchsia "
            + "gray green groove handheld hebrew help hidden hide high higher icon inline-table inline inset inside invert italic "
            + "justify landscape large larger left-side left leftwards level lighter lime line-through list-item local loud lower-alpha "
            + "lowercase lower-greek lower-latin lower-roman lower low ltr marker maroon medium message-box middle mix move narrower "
            + "navy ne-resize no-close-quote none no-open-quote no-repeat normal nowrap n-resize nw-resize oblique olive once open-quote outset "
            + "outside overline pointer portrait pre print projection purple red relative repeat repeat-x repeat-y rgb ridge right right-side "
            + "rightwards rtl run-in screen scroll semi-condensed semi-expanded separate se-resize show silent silver slower slow "
            + "small small-caps small-caption smaller soft solid speech spell-out square s-resize static status-bar sub super sw-resize "
            + "table-caption table-cell table-column table-column-group table-footer-group table-header-group table-row table-row-group teal "
            + "text-bottom text-top thick thin top transparent tty tv ultra-condensed ultra-expanded underline upper-alpha uppercase upper-latin "
            + "upper-roman url visible wait white wider w-resize x-fast x-high x-large x-loud x-low x-slow x-small x-soft xx-large xx-small yellow";
    String fonts = "[mM]onospace [tT]ahoma [vV]erdana [aA]rial [hH]elvetica [sS]ans-serif [sS]erif [cC]ourier mono sans serif";

    List<RegExpRule> _regExpRuleList = new ArrayList<RegExpRule>();
    _regExpRuleList.add(new RegExpRule(RegExpRule.multiLineCComments, "comments")); // multiline comments
    _regExpRuleList.add(new RegExpRule(RegExpRule.doubleQuotedString, "string")); // double quoted strings
    _regExpRuleList.add(new RegExpRule(RegExpRule.singleQuotedString, "string")); // single quoted strings
    _regExpRuleList.add(new RegExpRule("\\#[a-fA-F0-9]{3,6}", "value")); // html colors
    _regExpRuleList.add(new RegExpRule("(-?\\d+)(\\.\\d+)?(px|em|pt|\\:|\\%|)", "value")); // sizes
    _regExpRuleList.add(new RegExpRule("!important", "color3")); // !important
    _regExpRuleList.add(new RegExpRule(getKeywordsCSS(keywords), Pattern.MULTILINE, "keyword")); // keywords
    _regExpRuleList.add(new RegExpRule(getValuesCSS(values), "value")); // values
    _regExpRuleList.add(new RegExpRule(getKeywords(fonts), "color1")); // fonts
    setRegExpRuleList(_regExpRuleList);

    setHTMLScriptRegExp(new HTMLScriptRegExp("(?:<|<)\\s*style.*?(?:>|>)", "(?:<|<)\\/\\s*style\\s*(?:>|>)"));

    setCommonFileExtensionList(Arrays.asList("css"));
  }

  protected static String getKeywordsCSS(String str) {
    return "\\b([a-z_]|)" + str.replaceAll("\\s", "(?=:)\\\\b|\\\\b([a-z_\\\\*]|\\\\*|)") + "(?=:)\\b";
  }

  protected static String getValuesCSS(String str) {
    return "\\b" + str.replaceAll("\\s", "(?!-)(?!:)\\\\b|\\\\b()") + ":\\b";
  }
}


This is a professional hydraulic stone burier for preparation of lawn beds of all sizes. The stone burier mills the soil, buries eventual stones and other objects up to 150 mm depth in a single pass, making a milled and tamped topsoil. Working depth is adjustable with the rear field roller. With the optional seeding unit you are able to make a ready lawn surface on one pass.
1130 stone burier is not compatible with 313S, 320S, 745, 750, 755i and 760i.
1300 stone burier is not compatible with 220, 225, 225LPG, 313S, 320S, E5 and E6.
1500 stone burier is not compatible with 220, 225, 225LPG, 313S, 320S, 420, 423, 520, 523, 528, E5, E6 and R28.


Reported as the industry's first single-chip ADSL router, the highly integrated CX82310 includes all of the hardware functions of a ARM-based network processor, ADSL discrete multi-tone (DMT) engine, analog front end (AFE), and line driver. The device is compliant with full-rate ADSL and splitterless G.lite standards and supports USB and 10/100 Mb/s Ethernet. Data transfer rates are 8 Mb/s downstream and 1 Mb/s upstream. Other features include a 16-bit wide, parallel expansion bus that can provide an interface to a PCMCIA 802.11b wireless system or for interfacing to a V.92/V.90 backup system. Available in a 256-pin FPBGA, price is $23 each/10,000. CONEXANT SYSTEMS, INC., Newport Beach, CA. (949) 483-6775.


text:
Home / Books / ABANDONED IN BERLIN by John R. Cammidge
ABANDONED IN BERLIN by John R. Cammidge
Publisher: Gatekeeper Press (September 5, 2018)
Publication Date: September 5, 2018
Categories Books, Featured Tag History
Missing Memories by Carole McKee
The Day for You the Night for Me by m/s N Sherry
ALLURE OF A MAN by Rik Francis
Political Dirty Trick by James R. Callan
Abandoned in Berlin invites the reader to decide if anti-Semitism in Germany ended after the war or was simply concealed by a new set of West German laws. The story uncovers the history of a prestigious block of Jewish-owned apartments in West Berlin, expropriated under National Socialism at the end of March 1936. The leading characters are a widow and her two teenage daughters, with the story narrated in the third person by Hilda, the only child of the youngest daughter, who currently lives in Novato, northern California. Uncovering the family history begins during June 2016 when Hilda visits Berlin to discover the home where her mother lived as a child and teenager. Through diligent research and the help of people and organizations in Berlin, Britain, the United States, and Israel, a story of persecution, discrimination, courage, and survival emerge.
Important events are exposed that begin in December 1929 when the father of the family dies suddenly of natural causes and leaves his wife to bring up the two adolescent daughters and manage the apartment business in the Charlottenburg-Wilmersdorf district of Berlin. The youngest girl legally inherits a share of the property, but because she is under age-21 and has no father, she is placed under the "care" of a Nazi Guardianship Court during late 1933. As a consequence, the Court controls all financial matters affecting the property. Slowly its requirements squeeze Hilda's family out of their home and rental business, and then out of Germany. Not until during the early 1950s can the survivors pursue restitution under newly-created West German jurisprudence. What happens at this time is described in Abandoned in Berlin.
The author was born in England and has lived permanently in California since 1990. He spent nearly fifty years in Human Resources with organizations such as Ford Motor Company, Bank of America, and Stanford University and the University of California system's office, and took up writing five years ago. He has already published the historical fiction "An Unplanned Encounter" under a pseudonym and will publish literary fiction "Bonfire Nights" at the end of 2018. This latter story is about growing up in Britain during the 1960s and '70s and combines romance with business and a passion for bird watching. The novella "Abandoned in Berlin" came about as a result of a trip to Berlin in June 2016 with his friend Hilda. His writing is entertaining, rich with feelings, historically accurate, and honest. He writes to educate and inspire. More author details can be found on his website at johnrcammidge.com.
Inside The Mind of A Jewelry Designer by Alene Geed
Worth The Wait by Tamara Whitlow
Absolute Duty by Owen Seymour
I Am My Own Cause, the Third Act by Charles K. Poole
Badges Prequel by Danielle Norman
Freedom's Light by Robert Saniscalchi
The Cowboy Meets His Match by Margaret Brownley
Interlude in Kosovo by Robert Hedley
Man Mission by Eytan Uliel
If Trees Could Talk by Holly Worton


text:
The Mets cannot resist promoting Eric Orze to the big league bullpen
Edwin Diaz is a free agent after the 2022 season. If he leaves New York, who could take over?
Eric Orze is a guy I envision getting a chance to close games for the Mets. He had a pretty awesome season in 2021, going 4-2 with a 3.08 ERA in 49.2 innings of relief.
What makes Orze's performance even better is that he lowered his ERA each level he rose. It went from 4.05 in High-A to 2.60 in Double-A and finally to 2.19 in Triple-A. Orze also managed to finish 14 games and pick up five saves. Minor league bullpens won't always have a closer. If they did, I think Orze, in what was his first professional season, would have won it.
Now seemingly one step away from reaching the big leagues, Orze looks like a guy who could get some relief innings for the major league Mets in 2022 and not just the one in Syracuse. Taken in the fifth round of the 2020 draft, he has risen quickly through the system. His next stop is in Queens as he looks to break the drought of the franchise's inability to produce quality relievers from the minor league system.
Orze shouldn't make the Opening Day roster. However, as soon as bodies end up on the IL, he should be one of the first the Mets turn to for some help.


text:
Kindergartner raises $450 for breast cancer research by selling cookies
Submitted by brenda.johnson on Thu, 02/20/2020 - 16:15
27740002.jpeg 936.84 KB
SPANISH FORK — One kindergarten student from Brockbank Elementary raised almost $500 to help with breast cancer research with the help of friends, family, total strangers and some homemade cookies.
None of that would have been possible without a big goal and an even bigger heart.
Near the end of January, a member of the school's "Kid's Power Committee" came to Ace Sampson's class to present a charity the school would raise funds for that year, which was the Breast Cancer Research Foundation. That student shared a story that really touched Ace.
"There was a sixth grade student who told the class about a friend of hers who lost her mom to breast cancer," Ace's mom, Jessica Sampson, said. "That must have really affected him because when I picked him up from school that day, the first thing he said was 'Mom we need to head to the bank and get $100 dollars from my bank account because I'm gonna donate it to breast cancer!'"
While Sampson was thrilled that her son wanted to do so much to help the cause, she thought $100 was a lot for him to donate.
"At first I was like, 'OK, well how about we bring like $30 dollars?' And he was like, 'No, Mom. I wanna donate a lot of money, I wanna help cure breast cancer!'" Sampson recalled. "So later his dad and I talked to him, and he was dead set on $100."
Knowing there was nothing they could do to change their son's mind, but also wanting to encourage his desire to do good, the Sampsons decided Ace could earn $100 through his own fundraiser. Unsure of how to earn the money, Ace asked an aunt who suggested they make cookies. Ace loved the idea, so on Jan. 27, the day the school's fundraiser began, Operation Cookie Sale was on.
Ace's aunt and mom made five dozen cookies, and he sold about a dozen after school before it got too dark for him to be out. With four dozen cookies left to sell, the Sampsons took to Instagram.
"Ace put together a cute little sales pitch, and I posted it on my Instagram page," Sampson said. "We were just trying to sell the last four dozen cookies, and then my phone started going off like crazy with people ordering cookies. Within an hour we had so many orders that we had to stop for the night."
The trio continued to make cookies the next day to fulfill more orders coming from as far as Nevada and Illinois. According to Sampson, in just 24 hours they frosted and delivered 25 dozen cookies.
"The coolest part was a lady bought cookies for us to deliver to her aunt who is going through breast cancer herself, and we got to make a surprise delivery to her. People even donated without wanting cookies, and in 24 hours he had made $450 dollars," Sampson said.
The following Monday, Ace brought the money to his school; teachers, staff and students were blown away with the kindergartner's success.
"His teacher was shocked when we told her what he had done, and the school has been very cute with Ace letting him know how special it was he did this," Sampson said.
The school's fundraiser ended on Valentine's Day, and school officials said students raised a total of $1,763.65. A school spokesperson said the fundraiser was a success in large part due to Ace's donation.
While the amount of support and money that Ace was able to earn may have been shocking, according to Sampson, she was not surprised her son decided to do this.
"Ace has a big personality and people are drawn to him when they meet him," Sampson said. "I probably wouldn't have been so motivated to help him make his goal of $100 if he wasn't so persistent with wanting to help fight breast cancer. I could tell he was so moved by what the student had shared. It was never about the competition the school was doing. He really wanted to help fight breast cancer and my husband and I just couldn't not help him accomplish this.
"On his way to the school to give his money to the PTA he told his sister, 'Rosie! I'm helping to cure breast cancer!' Isn't that amazing?"
Story & Photo by Arianne Brown. KSL.com


text:
Kir1.1 / ROMK1
Block of Kir1.1 on the Patchliner
Bhave et al. (2011)
Kir1.1 | ROMK1 I Potassium Voltage-Gated Channel Subfamily J Member 1
Inward-rectifier potassium ion channel
Subgroups:
Seven families channels demonstrate robust inward rectification: Kir1.1; Kir2.1 - Kir2.4; Kir3.1 - Kir3.4, Kir4.1 - Kir4.2; Kir5.1, Kir6.1 - Kir6.2; Kir7.1
Topology:
The channel protein contains two membrane spanning alpha helices denoted as M1 and M2. Four identical subunits form a functional homotetramer, heterotetramers can combine with members of the same subfamily
Kir1.1 Background Information
Kir1.1 is also known as ROMK (renal outer medullary potassion channel) or ATP-sensitive inward rectifier potassium channel 1. It is an ATP-dependent potassium channel that transports potassium out of cells. It plays an important role in potassium recycling in the thick ascending limb (TAL) and potassium secretion in the cortical collecting duct (CCD) of the nephron.
KCNJ1
Human Protein:
Tissue:
Kidney and pancreatic islets, lower levels in skeletal muscle, pancreas, spleen, brain, heart and liver.
Function/ Application:
Plays a major role in potassium homeostasis in the kidney
Bartter syndrome 2, Antenatal Bartter Syndrome
Interaction:
Associated subunit: NHERF2 (Sodium-hydrogen exchange regulatory cofactor 2). Interacts with serum/glucocorticoid regulated kinase 1 (SGK1), Solute carrier family 9, subfamily A (SLC9A3R2/NHERF2), CFTR, WNK lysine deficient protein kinase 4, SH3 domain containing ring finger 1
Modulator:
Barium, ATP, glimepiride, glycodiazine, minoxidil, tolbutamide, glyburide, tertiapin-Q
Assays:
Patch clamp
Recommended Reviews:
Kubo et al. (2005) International Union of Pharmacology. LIV. Nomenclature and Molecular Relationships of Inwardly Rectifying Potassium Channels. Pharmacol Rev 57(4):509-526
Prof. Dr. Jerod Denton - Statement about the Patchliner
"One of the biggest advantages of the Patchliner for our lab is that it enables students and fellows without formal training in patch clamp electrophysiology to begin generating meaningful data almost immediately. Instead of spending a couple of frustrating months learning the motor skills and hand-eye coordination necessary for conventional patch clamping with a microscope and micromanipulator, they spend that time designing and executing experiments, generating, evaluating and interpreting data and moving the project forward. The Patchliner also enables experimental flexibility that would be very difficult or impossible with conventional patch clamp rigs. For example, a talented undergraduate in the lab just finished up a series of intracellular drug application experiments. These studies would be difficult for the seasoned electrophysiologist and nearly impossible for an undergraduate student. However, the Patchliner allowed them to be completed in a very short period of time.
Another major advantage is that the Patchliner enables us to rapidly confirm or exclude hits from our primary fluorescence-based high-throughput screen using gold-standard electrophysiological methods. And the quality of the recordings rivals that of a conventional patch clamp rig. In fact, our first observations of pore "knock-off" of a new ROMK inhibitory small-molecule came from the Patchliner. These early observations from high-quality Patchliner recordings provided a clear direction for subsequent mutagenesis work aimed at defining the binding site of this molecule within the cytoplasmic channel pore."
Jerod S. Denton, Ph.D.,Assistant Professor of Anesthesiology and Pharmacology
Vanderbilt University Medical Center, Nashville, TN, USA
2011 - Development of a selective small-molecule inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel
Patchliner publication in Molecular Pharmacology (2011)
Bhave G., Chauder B.A., Liu W., Dawson E.S., Kadakia R., Nguyen T.T., Lewis L.M., Meiler J., Weaver C.D., Satlin L.M., Lindsley C.W., Denton J.S.
2009 - High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1
Lewis L.M., Bhave G., Chauder B.A., Banerjee S., Lornsen K.A., Redha R., Fallen K., Lindsley C.W., Weaver C.D., Denton J.S.
Target-based Database
Go back to overview here:
Find out more about our Applications
Here you find an overview about our applications:


text:
AI-Driven Software ProstatID by Bot Image Receives FDA Clearance for Diagnosis and Detection of Prostate Cancer
Posted on: August 18, 2022 in News | Medical Device News | Medical Device Diagnostics News
By: Nadia Stec, MSc
Bot Image announced that their ProstatID software received clearance from the US FDA for use in detecting and diagnosing prostate cancer by combining AI with traditional MRI scanning.
Over the past several years, artificial intelligence (AI) tools have been developed by researchers with the goal of making cancer imaging and screening faster and more accurate, though there is still some skepticism around whether they are ready for larger-scale use in doctor's offices.
Naturally, people may not automatically trust AI — these tools use algorithms to learn from data to make decisions or predictions. To train AI, scientists provide it with data in the form of rules, instructions, images, or other material for it to "learn" from and analyze to make decisions much like a human would.
The aim of AI is to have it display human-like "intelligent behaviour." In the case of cancer screening or diagnosis, this means recognizing visual images, like MRI scans, of people who have a specific form of cancer and those who do not.
Bot Image is one company that aims to provide AI-driven software to improve the accuracy and speed of prostate cancer detection and diagnosis.
Last week, Bot Image announced in a press release that their ProstatID software received clearance from the US Food and Drug Administration (FDA) for use in detecting and diagnosing prostate cancer by combining AI with traditional MRI scanning.
ProstatID is available in the form of software as a service (SaaS) and is both HIPAA-compliant and secure as its use requires a secure VPN connection between a radiology department's server or MRI system and the cloud-hosted ProstatID server.
XTALKS WEBINAR: Accelerate Product Approval Using In Silico Modeling & Simulation
Live and On-Demand: Thursday, September 22, 2022, at 10am EDT (3pm BST/UK)
Register for this free webinar to explore the potential for including in silico modeling and simulation as an integral part of the product development plan.
Training ProstatID to Detect Prostate Cancer
Dr. Randall W. Jones, Bot Image founder and CEO, explains that "Prostate cancer screening and detection methods adoption has changed little over the past 30 years, despite the mountain of evidence pointing to the efficacy of superior technologies and the futility of the old methods." This has unfortunately resulted in unnecessary premature deaths of numerous men.
The approval of ProstatID is progress in the mission to save lives with early and accurate detection and demonstrates time and cost savings for both patients and medical providers.
The AI was trained with thousands of MRI scans, radiological interpretations, biopsies, and pathology lab results. The software's algorithm assigns a cancer probability to any suspicious cancer lesions it detects. Subsequently, it provides a diagnostic case score called a PI-RADS score (Prostate Imaging Reporting and Data System).
Two clinical studies with twenty-five US-based radiologists used this AI-based method, and it resulted in significantly improved radiologic interpretation accuracy. The improved accuracy was based on improved detection of cancer and fewer false positives when radiologists used ProstatID.
The software's ability to detection lesions and assign a probability score to patient MRI scans surpasses the capabilities of existing technologies that may improve on-screen visualization of MRI cases but fall short in the actual detection and diagnosis of prostate cancer.
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Home ENTERTAINMENT Why does Trump support singer Cher's comments on migrants?
Why does Trump support singer Cher's comments on migrants?
the President Donald Trump found on Monday unusual new ally in his battle against the Democrats for the illegal immigration: the pop star and, in general, fierce criticism Cher.
"I understand that I am helping immigrants in difficulty, but MY CITY (Los Angeles) DOESN'T CARE FOR OUR PEOPLE", tweeted Cher on Sunday. "If my state can't take care of them (many are veterans), how can you take care of others?"
Its publication, in which the eccentric use of punctuation, capital letters and grammar are assimilated to those of the famous writing style of the president, have been exploited by the Republicans.
They argue, like Trump, that the illegal migration has reached emergency levels requiring drastic actions. From them, Democrats they say that Trump's policies have created much of the problem and that he exploits tensions for his political advantage.
To prove his point, Trump threatened to send a large number of migrants to the cities and were led by democrats who declared themselves "sanctuaries"for undocumented foreigners, including California.
Next articleGreat quiz: the losers will be fired!


Cosmos provides unique guided tour experiences in America's national parks. Cosmos takes you to the most spectacular national parks in America including Grand Canyon, Yellowstone, Yosemite, Bryce and Zion National Parks, and many more must-see national treasures. Look for the GoParks! logo.
Nobody can show you the wonders of America's national parks like Cosmos. And today, nobody is more committed to keeping them wondrous, either.
Choose from our great collection of national park escorted tours that feature overnights and/or significant visits in U.S. national parks-just look for the "GoParks! Tours" logo throughout the vacations on the Web site. We can't wait to introduce you to these incredible sights and experiences!
Explore the captivating canyonlands and experience spellbinding landscapes on this unforgettable National Parks tour! You'll start and end in Las Vegas, and overnight along the way inside Grand Canyon National Park; near Monument Valley in Kayenta; near Lake Powell in Page; ...Read More.
History comes alive on this East Coast tour featuring some of the East Coast's most thrilling cities: Boston, New York City, Philadelphia and Washington D.C. On this East Coast tour, enjoy sightseeing in each city. With an expert Local Guide—someone who knows the ins and outs of ...Read More.
This Alaska tour is a dream come true for value-minded travelers seeking to experience Alaska's breathtaking scenery and thrilling experiences. You'll start and end your tour in Anchorage with overnights also in Denali National Park and Valdez. In between destinations, you'll ...Read More.
From the gorgeous national parks to the thrilling cities, this western U.S. tour through California, Arizona, and Nevada features unique rock formations, scenic drives, deep canyons, and sparkling waterfalls and lakes—not to mention fun in some of the world's most famous cities. ...Read More.
Breathtaking glacier lakes, rugged mountains, stunning waterfalls, fascinating geysers, and the "big sky"—these and much more wait for you on this National Parks tour. Your tour starts in Salt Lake City, ends in Seattle, and overnights along the way in Jackson, West Yellowstone, ...Read More.
Marvel at premier natural wonders on this multi-state vacation that focuses on some of the West's most scenic national parks. This National Parks tour starts in Rapid City and ends in Las Vegas. In between, you'll visit Mount Rushmore, Yellowstone National Park, Grand Teton ...Read More.
Marvel at premier natural wonders on this multi-state vacation that focuses on some of the West's most scenic national parks. This National Parks tour starts in Denver and ends in Las Vegas. In between, you'll visit Mount Rushmore, Yellowstone National Park, Grand Teton National ...Read More.
Breathtaking scenery, spectacular wildlife, and incomparable photo opportunities await you on this national parks tour through the West's best-known national and state parks. Tour highlights include your overnight stay inside Grand Canyon National Park, where you can witness the ...Read More.
Experience the best of the West on this thrilling adventure—with its vibrant cities, spectacular mountains, scenic drives, and unique rock formations. This western U.S. tour begins and ends in Los Angeles with overnights along the way in Palm Springs, Scottsdale, Williams, Las ...Read More.
Mother Nature has loaded the West with stunning scenery, and on this National Parks tour, you'll witness some of natures finest. From red-rock formations and breathtaking canyons to free-flowing rivers and alpine landscapes, you'll marvel at magnificent scenery throughout this ...Read More.
This Alaska tour is a dream come true for value-minded travelers seeking to experience Alaska's breathtaking scenery and thrilling experiences. Your tour includes seven nights aboard your Alaska cruise ship and overnights in Anchorage, Denali National Park, and Valdez. In ...Read More.
Follow legendary Route 66 and see how Americans traveled from the 1920s through the 1960s. This historic route begins in Chicago, travels through eight states, and ends in Los Angeles. On this Route 66 tour, you'll get the opportunity to travel to some of the cities along Route ...Read More.
This Alaska and the Yukon Territory tour features many of the most popular scenic vistas that Alaska and the Yukon Territory have to offer—beginning and ending in Anchorage. Along the way, take a boat to view breathtaking Mears Glacier on Prince William Sound and watch for ...Read More.
Breathtaking glacier lakes, rugged mountains, stunning waterfalls, fascinating geysers, tremendous slabs of ice breaking off and "calving" into the sea, and the "big sky"—these and much more wait for you on this National Parks tour with an Alaska cruise. Your tour starts in Salt ...Read More.