Florida offers great weather year round, and the fact that snow and ice never factor into the equation means drivers don�t have to focus on the overall vehicle handling as they do in other states. The best selling cars �... What is a bill of sale? It's a written document that helps to provide proof of transfer of ownership of personal property, such as a car. It will contain important information, including the purchase price of the vehicle, the sale date, a description of the vehicle, and the names of the buyer and seller.
In order to properly complete a Florida title upon sale, follow these instructions: Seller / Registered Owner Title Transfer Instructions. Florida maintains titles electronically in their database.
Cash for Cars Florida . Cash For Cars in Florida. Even in sunny Florida we can all find ourselves in some financial struggle. You might be under pressure to sell your car for cash or you just want to find the best deal out there when selling your vehicle.
Thousands of vehicles are sold in Florida every year. As a seller, there are certain things you should know before selling a vehicle, including the process to transfer the title.


text:
"Solo" is the first ever Star Wars "flop"
New data suggests that Solo: A Star Wars Story is the first ever Star Wars film to make a loss within its second week of release.
After initially missing its North American opening targets by around $30 million, box office revenue dropped off a further 65% the following weekend. According to SlashFilm, the film has only brought in $264 million worldwide which, while seeming like a lot of money, is very low for a Star Wars film, especially as its production budget was reported to be around the $250 million mark.
Box office estimates put #SoloAStarWarsStory's 2nd domestic weekend at just $29.3M, a massive drop of 65.3%. Internationally, the film has made only $115.3M to date. With a reported budget of over $250M, it is officially the first Star Wars movie to flop. pic.twitter.com/hYPShuwsMD
— Adam B. Vary (@adambvary) June 3, 2018
So why wasn't it a success? Analysts are pointing at a number of factors, including the timing of release (clashing with Infinity War and Deadpool 2) and the firing of original directors Phil Lord and Chris Miller, but veteran media analyst Doug Creutz puts it down to a lacklustre marketing effort. In the report, he writes that the film simply didn't have a big enough hype window. While the teaser for Rogue One came out 247 days before the movie release, the Solo teaser arrived just 108 days before the premiere date.
"Disney's marketing department, in our opinion, had one job: sell audiences on Alden Ehrenreich as Han Solo (who we thought did a creditable job in the movie with very tough shoes to fill)," he continues. "The teaser, by our count, only had about 10 seconds of screen time where Ehrenreich's face was clearly in the picture – not, in our opinion, nearly enough. In general, we felt like the Solo marketing campaign didn't get fully up to speed until about a month before the movie came out, and that is simply too short of a window for a big franchise picture."
The film received mixed reviews and currently has a 71% critic score on Rotten Tomatoes (and 65% audience score). That alone won't have been enough to kill its box office figures though, as even Attack of the Clones fared better with a critic score of 66%. Regardless of the financials, the original Han Solo, Harrison Ford, apparently loves the film and has been "raving about it", according to director Ron Howard.
[arve url="https://www.youtube.com/watch?v=jPEYpryMp2s"]
Via: SlashFilm
Tags: Harrison Ford, Ron Howard, Solo: A Star Wars Story, Star Wars

redpajama_set_name: RedPajamaCommonCrawl


text:
<?php
namespace Payum\Core\Tests\Functional\Bridge\Doctrine\Entity;

use Payum\Core\Security\SensitiveValue;
use Payum\Core\Tests\Functional\Bridge\Doctrine\OrmTest;
use Payum\Core\Tests\Mocks\Entity\Payment;

class PaymentTest extends OrmTest
{
    /**
     * @test
     */
    public function shouldAllowPersistEmpty()
    {
        $entity = new Payment();
        $this->em->persist($entity);
        $this->em->flush();

        $this->assertSame([$entity], $this->em->getRepository(Payment::class)->findAll());
    }

    /**
     * @test
     */
    public function shouldAllowPersistWithSomeFieldsSet()
    {
        $order = new Payment();
        $order->setTotalAmount(100);
        $order->setCurrencyCode('USD');
        $order->setNumber('aNum');
        $order->setDetails('aDesc');
        $order->setClientEmail('anEmail');
        $order->setClientId('anId');
        $order->setDetails(array('bar1', 'bar2' => 'theBar2'));

        $this->em->persist($order);
        $this->em->flush();

        $this->assertSame([$order], $this->em->getRepository(Payment::class)->findAll());
    }

    /**
     * @test
     */
    public function shouldAllowFindPersistedOrder()
    {
        $order = new Payment();

        $this->em->persist($order);
        $this->em->flush();

        $id = $order->getId();

        $this->em->clear();

        $foundOrder = $this->em->find(get_class($order), $id);

        //guard
        $this->assertNotSame($order, $foundOrder);

        $this->assertEquals($order->getId(), $foundOrder->getId());
    }

    /**
     * @test
     */
    public function shouldNotStoreSensitiveValue()
    {
        $order = new Payment();
        $order->setDetails(array('cardNumber' => new SensitiveValue('theCardNumber')));

        $this->em->persist($order);
        $this->em->flush();

        $this->em->refresh($order);

        $this->assertEquals(array('cardNumber' => null), $order->getDetails());
    }
}

redpajama_set_name: RedPajamaGithub


Bill shares his thoughts on some recent events and theories about Trump's super secret agenda to dethrone the globalists, then gets into the main topic of the motion picture industry, discussing the role of non-jews, how the old-time Hollywood films were regulated and why, the Third Reich in 3D, and more.
Is Marlene Dietrich becoming a running gag to mock German listeners, Bill?
Call me humourless but I hate to hear an outright enemy of my people being called a nice person here on this network. If you didn't believe what I wrote (commenting on comments) you could have done a search and would have seen yourself that it's true what I said.
Thank you. I am only now learning about her offenses.
Interesting find. There might be something to that "sexual harassment" training" program. The first half-hour might be the best part of the presentation. This show was far from my "best" effort.
Blame it on the holiday blues.
But I did learn a lot about Hollywood.


text:
package com.batfia.apprentice.memento.widget;

import android.view.View;
import android.widget.ImageView;
import android.widget.TextView;

import com.batfia.apprentice.R;

import com.batfia.apprentice.memento.inner.Formatter;
import com.batfia.apprentice.memento.model.DatabaseModel;
import com.batfia.apprentice.memento.model.Note;
import com.batfia.apprentice.memento.widget.template.ModelViewHolder;

public class NoteViewHolder extends ModelViewHolder<Note> {
	public ImageView badge;
	public TextView title;
	public TextView date;

	public NoteViewHolder(View itemView) {
		super(itemView);
		badge = (ImageView) itemView.findViewById(R.id.badge_icon);
		title = (TextView) itemView.findViewById(R.id.title_txt);
		date = (TextView) itemView.findViewById(R.id.date_txt);
	}

	@Override
	public void populate(Note item) {
		if (item.type == DatabaseModel.TYPE_NOTE_DRAWING) {
			badge.setImageResource(R.drawable.fab_drawing);
		} else {
			badge.setImageResource(R.drawable.fab_type);
		}
		title.setText(item.title);
		date.setText(Formatter.formatShortDate(item.createdAt));
	}
}


text:
FeatureGiving BackSOCIAL SCENE
The Junior League of Pasadena Celebrates 90 Years of Service with a Birthday Party
admin — June 13, 2016
The Junior League of Pasadena celebrates 90 years of evolving community service Tuesday at a special birthday celebration at the Kidspace Children's Museum, a facility which actual is the result of a 1978 Junior League pilot project.
The all-women nonprofit is committed to promoting voluntarism, developing the potential of women and improving the community through the leadership of trained volunteers.
"We strive to have the most effective volunteer force in the community," said JLP Operations Director Charlotte Miles.
At first, when founded in 1926 by a group of young women, the group was called the Junior Aid Society. Many early-day members were newly-married women of means who could dedicate time to volunteering within the community.
Over the years, the generations-old model of daytime volunteering and meetings has proved to be impractical in the 21st century as a large portion of women now work during the day, prompting the JLP to meet in the evenings and weekends.
The nonprofit has established popular programs over the years such as Kids in the Kitchen, Girls Rock!, Nurturing Children Through Family Support and many more that exemplify the creative and impactful efforts the JLP aim to establish.
Physical reminders of JLP's legacy can be seen all over Pasadena as well, including Kidspace Children's Museum and the Pasadena Senior Center among several others are products of what JPL has created in the past in order to provide and establish services for community groups that were otherwise underserved in areas of education for children and elderly care.
2011 marked the year JLP changed the way in which the organization served the community when it transitioning to a "partnership model" to provide volunteer and financial support to local nonprofits.
"JLP is a starting point for women in Pasadena who will become better equipped to contribute to the dozens of nonprofits in Pasadena," said Miles. "It used to be stay-at-home mothers. Now we're seeing working 25 year old women who are trying to figure out what they can do in the community that will make the biggest impact."
Nine decades later and over 400 members strong in 2016, the JLP today is a multifaceted organization that goes beyond daytime youth volunteer activities and concentrates on the development of the women involved.
"We've evolved into something more than just a community service organization," said JLP President Jennifer Allan-Goldman.
"We are helping women build upon the training they are receiving on the job and learn how to apply their skills at other organizations in nearby communities," explained Allan-Goldman.
The organization recently performed internal research and found that there is a demand for business oriented workshops and skill development for women in the workforce that ranges from searching for a first job to switching up a career entirely.
From this, JLP established a set of curriculum termed Business Entrepreneur Leadership Skills (BELS).
"We've changed our focus area in the past decades to be more pertinent to what is needed in the city. BELS is an opportunity for us to train newer, younger women on how to be a leader in the community," explained Miles.
The 90-year-old JLP chapter is a part of the Association of Junior Leagues International comprised of over 150,000 women members and 291 additional leagues in the US, UK, Canada and Mexico.
According to Miles majority of JLP members are on the sustainer level which means they have completed at least five years of active membership. The JLP is always looking for new members to help make an impact.
JLP's birthday celebration will be held at Kidspace Children's Museum Tuesday from 6 p.m. to 8 p.m. Food, beverages, and entertainment will be provided for all in attendance. 2016- 2018 AJLI President and JLP member, Carol Scott, will be the keynote speaker.
For more information contact the Junior League of Pasadena at (626) 796-0244 or visit their website at www.jlpasadena.org.
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You can RSVP online for a SIREN Going Solar presentation. Occasionally our Events calendar contains notices of events offered by other organizations. In such cases, registration contacts are provided in the listing.
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Well over here we are still on Easter holidays and the Easter eggs are half price! The kids are still away from school and bored so having bought some little Easter eggs cheap I thought we could make some Easter Nests which, because it is after Easter, we will call Spring treats.
It is a macaroon mix and filled with chocolate spread and small egg. The mixture makes about 16 nests.
Whisk the egg whites until stiff then add the lemon/lime juice and a little sugar and keep whisking. Gradually add the remaining sugar and whisk until the mixture is shiny. Fold in the coconut, almonds and vanilla. Spoon the mixture into paper cases and make a small depression in each one.
Bake for 12 minute until set. Cool on a wire rack and when slightly cool add a teaspoon of chocolate spread and three eggs to each. The children had one still hot from the oven with a glass of milk but they go equally well with tea.


Oil reserves in Iraq are considered the world's fifth -largest proven oil reserves, with 140 billion barrels. The sources for this oil is primarily located in the Shiite Muslims-majority and Arab Sunni Muslims-dominated areas on the other hand are comparatively lacking.
As a result of military occupation and civil unrest, the official statistics have not been revised since 2001 and are largely based on 2-D seismic data from three decades ago. International geologists and consultants have estimated that unexplored territory may contain vastly larger reserves. The majority of Iraq's proven reserves of oil comes from the following cities: Basra (Being #1), Baghdad (Being #2), Ramadi (Being #3), and finally, Ba'aj (Being the last oil rich city).
A measure of the uncertainty about Iraq's oil reserves is indicated by widely differing estimates. The U.S. Department of Energy (DOE) estimated in 2003 that Iraq had 112 billion barrels (17.8×10^9 m3). The United States Geological Survey (USGS) in 1995 estimated proven reserves were 78 Gbbl (12.4×10^9 m3). Iraq's prewar deputy oil minister said that potential reserves might be 300 Gbbl (48×10^9 m3). The source of the uncertainty is that due to decades of war and unrest, many of Iraq's oil wells are run down and unkept. Repairs to the wells and oil facilities should make far more oil available economically from the same deposits. Iraq may prove to contain the largest extractable deposits of oil in the entire Middle East once these upgrading and facility improvements have advanced.
After more than a decade of sanctions and two Gulf Wars, Iraq's oil infrastructure needs modernization and investment. Despite a large reconstruction effort, the Iraqi oil industry has not been able to meet hydrocarbon production and export targets. The World Bank estimates that an additional $1 billion per year would need to be invested just to maintain current production. Long-term Iraq reconstruction costs could reach $100 billion or higher, of which more than a third will go to the oil, gas and electricity sectors. Another challenge to Iraq's development of the oil sector is that resources are not evenly divided across sectarian lines. Most known resources are in the Shiite areas of the south and the Kurdish north, with few resources in control of the Sunni population in the center.
In 2006, Iraq's oil production averaged 2.0 million barrels per day (320×10^3 m3/d), down from around 2.6 Mbbl/d (410×10^3 m3/d) of production prior to the coalition invasion in 2003. Iraq's reserve to production ratio is 158 years. After the end of the invasion the production increased on a high level, even though there is an invasion from the so-called ISIL the production in March 2016 stood at 4.55 million barrels a day. Which seems to well become a new all-time peak year for Iraq if OPEC talks about freezing or reduce production held in April 2016 will not lead to a reduction. The old peak was 1979 with 171.6 million tons of oil compared to 136.9 million tons produced in 2011 and 152.4 million tons in 2012.
On June 30 and December 11, 2009, the Iraqi Ministry of Oil awarded contracts to international oil companies for some of Iraq's many oil fields. The winning oil companies entered joint ventures with the Iraqi Ministry of Oil, and the terms of the awarded contracts include extraction of oil for a fixed gain of $1.40 per barrel for the oil companies with the remainder going to Iraq. The fees will only be paid once a production threshold set by the Iraqi ministry of oil is reached.
Oil fields contracted include the "super-giant" Majnoon Field, Halfaya Field, West Qurna Field and Rumaila Field. The East Baghdad Field, situated in part under Sadr City, did not receive any bids and the Iraqi oil ministry is considering working the field itself. Oil minister Hussein al-Shahristani told Iraqi public television that the increasing oil production "would finance infrastructure projects across Iraq - schools, roads, airports, housing, hospitals".
↑ "International Energy Statistics". Eia.gov. Archived from the original on 2017-04-27. Retrieved 2017-04-24.
↑ "OPEC Share of World Crude Oil Reserves". OPEC. Archived from the original on 10 January 2015. Retrieved 11 January 2015.
↑ "27 maps that explain the crisis in Iraq". vox.com. Archived from the original on 1 June 2016. Retrieved 26 April 2018.
1 2 "Iraq Oil". Country Analysis Briefs. US Energy Information Administration. 2007. Archived from the original on 2008-05-09. Retrieved 2008-04-27.
↑ Gal Luft (2003). "How Much Oil Does Iraq Have?". The Brookings Institution. Archived from the original on 2017-04-25. Retrieved 2017-04-24.
↑ "Iraq oil output hits record high ahead of production freeze talks". rt.com. Archived from the original on 25 April 2016. Retrieved 16 April 2016.
↑ "statistical review of world energy 2013" (PDF). British Petroleum. Archived (PDF) from the original on 31 January 2016. Retrieved 16 April 2016.
↑ "Oil firms awarded Iraq contracts". Al Jazeera English. Archived from the original on 13 May 2011. Retrieved 11 January 2015.
1 2 "BP group wins Iraq oil contract". Al Jazeera English. Archived from the original on 6 September 2011. Retrieved 11 January 2015.


text:
Re-Pipe
ADA/WCAG Compliance
2048 Apex Court, Apopka, FL 32703
info@KGRplumbing.com
KGR Plumbing is the best plumbing company serving Central Florida since 1997. We need our customers as much as our customers need us. We believe in going way beyond the call of duty. Whatever it takes to ensure your complete satisfaction — give us a call. We service Central Florida including Brevard, Citrus, Hardee, Hernando, Hillsborough, Indian River, Lake, Manatee, Marion, Orange, Osceola, Pasco, Pinellas, Polk, Seminole, Sumter and Volusia counties and includes cities like Orlando, Palm Bay, Lakeland, Melbourne, Deltona, Daytona Beach, Kissimmee, Altamonte Springs, Sanford, Tampa, St. Petersburg, Clearwater.
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KGR Plumbing Cookie Notice
This site uses cookies to ensure the best experience. By continuing to use this website, you agree to their use.
Learn more about our privacy policy by clicking on Privacy Policy button.


text:
package com.android.reverse.request;

import com.android.reverse.collecter.DexFileInfoCollecter;
import com.android.reverse.collecter.ModuleContext;
import com.android.reverse.util.Logger;

public class BackSmaliCommandHandler implements CommandHandler {

	private String dexpath;

	public BackSmaliCommandHandler(String dexpath) {
		this.dexpath = dexpath;
	}

	@Override
	public void doAction() {
		// TODO Auto-generated method stub
		String filename = ModuleContext.getInstance().getAppContext().getFilesDir()+"/dexfile.dex";
		DexFileInfoCollecter.getInstance().backsmaliDexFile(filename, dexpath);
		Logger.log("the dexfile data save to ="+filename);
	}

}


text:
În geometrie un icositetraedru este un poliedru cu 24 de fețe. Există numeroase forme simetrice, iar unele dintre cele foarte simetrice au simetrie icosaedrică chirală

Exemple de icositetraedre

Convexe
Există patru poliedre Catalan cu câte 24 de fețe:

Există două poliedre Johnson cu câte 24 de fețe:

Alte poliedre convexe
 Prismă icosidigonală (bazele sunt 22-goane)
 Trunchi icosidigonal (bazele sunt 22-goane)
 Antiprismă endecagonală (bazele sunt 11-goane)
 Piramidă icositrigonală (baza este un 23-gon)
 Bipiramidă dodecagonală
 Cupolă endecagonală

Neconvexe

Stelate

Note

Bibliografie

Poliedre

redpajama_set_name: RedPajamaWikipedia


text:
Soy protein found to have consistent heart health benefits over time
Earth.com staff writer
Researchers at the University of Toronto have found that the heart health benefits of soy have not changed over time. The experts reviewed dozens of clinical trials from over the last 20 years and concluded that soy protein has consistently reduced both total cholesterol and low-density lipoprotein cholesterol, or "bad" cholesterol, which is associated with heart damage.
Since 2017, the U.S. Food and Drug Administration (FDA) has considered revoking the health claim on the connection between soy protein and a reduced risk of heart disease. The results of the current study, however, contradict the need for any such proposal by the FDA.
"At no time since the original claim for soy as a reducer of serum cholesterol has its ability been in question," said Professor David Jenkins. "It's been consistent since 1999. The data have not changed."
Across all 46 trials that the FDA cited as having "inconsistent findings," the experts found that the cholesterol-lowering effect of soy protein was unwavering.
"Sometimes you see a regression to the mean, where analyses with small studies produce big effects that diminish over time as sample sizes increase and results get more precise," said Professor John Sievenpiper. "We saw that with fish oil, for example. But in this case nothing has changed."
"These data strongly support the rationale behind the original FDA heart health claim for soy," said Professor Jenkins. "And it's important to note that while the reduction in cholesterol was less than five percent, if you put that together with other plant-based foods in a portfolio you get a much stronger effect."
Professor Jenkins recently helped to develop a dietary portfolio that identifies foods which can be combined to lower risk factors for heart disease by up to 30 percent, including nuts, plant-based protein, viscous fiber, and plant sterols. This portfolio has been incorporated into dietary guidelines by Heart UK and the European Atherosclerosis Society, and the FDA maintains health claims for several other plant foods.
"It's disheartening that the FDA has focused on soy," said Professor Jenkins. "We see similar data for other foods in the portfolio. If you knock out one leg of that stool then the others could be up for grabs, right when concerns about health and the environment are bringing plant-based eating into the mainstream."
"We're moving into an age of plant-based protein, and it would be a shame to see that shift undermined. Plant-based food producers, industry and retailers need all the help they can get, to make their products accessible."
The study is published in the Journal of the American Heart Association.
Image Credit: Shutterstock/Somrak Jendee
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Chelsea manager has been praised as a success in the Premier League so far with the good work he has done with the Chelsea team.
Chelsea are strong title contenders and sit second place in the Premier League table, Sarri has helped to keep smiles in the faces of the fans with his new possession football that is finer than what they have known in the past.
Football Psychologist Damian Hughes, a renowned Professor of Organisational Psychology and Change said all of the above has been able to happen in the West London side because of the human relationship the Italian manager has been able to establish at the club.
According to Hughes, Sarri has been able to establish a good connection with the players and ensures the same is obtainable between the players.
The Psychologist added that there is no much of a manager to players relationship at the Stamford Bridge under the former Napoli boss but a friendship relationship.
He noted that former manager Antonio Conte never had the kind of cohesion with his players like Sarri is having at the moment.
More so, the resurgence of Eden Hazard and David Luiz is an evidence that the manager as doing more to bring out the best in the players and also ensure they do more to fight for him.


Patient is a 37-year-old female with cystic fibrosis, recurrent nephrolithiasis who presents to clinic with asymptomatic bilateral kidney stones (8mm on right; 2mm on left) on imaging.
What type of stone and why cystic fibrosis (CF) is associated with kidney stones?
Patients with CF are at increased risk of calcium oxalate stones. This is thought to be primarily due to enteric hyperoxaluria and hypocitraturia.
Gut malabsorption can lead to hyperoxaluria. In malabsorption, there is an increase in free fatty acids (FFA), which bind to calcium and decrease the amount of calcium in the gut available to bind to oxalate. This leads to an increase in soluble oxalate which is absorbed in the gut (See Nezzal et al. NDT 2016 for an excellent discussion of enteric hyperoxaluria). Furthermore, chronic diarrhea from malabsorption leads to a chronic metabolic acidosis and hypocitraturia. In the urine, citrate is an inhibitor of the calcium oxalate complex. Higher urinary oxalate and less urinary citrate are associated with higher risk of stone formation.
What is the diagnostic work-up recommended in the above patient?
Initial evaluation of all patients with kidney stones, should include two 24-hour urine collections. Evaluating the urine composition provides crucial data for characterizing the patient's risk of kidney stone formation (both formation of new stones and growth of existing stones). For this patient, she also had a noncontrast CT that again demonstrated a 8mm stone in the lower pole of the right kidney. She also had 2 small (2-3mm) stones on the left (See Curhan, et al. "Diagnosis and acute management of suspected nephrolithiasis in adults" Up to Date, for more in depth discussion).
How to best manage this patient's stones?
For her existing calcium oxalate stones we need the help of our urology colleagues. Kidney stones less then 5mm are likely to pass on their own, without procedural intervention. For larger stones, discussion with the patient and urology is important. Options include medical expulsion therapy (MET), extracorporeal shock-wave lithotripsy (ESWL), ureteroscopy (URS), and percutaneous nephrolithotomy (PNL) (See also: AUA/EAU J Urol Vol 178, 2418-2434 2007 and prior blog). Our patient underwent urological evaluation and ureteroscopy to remove her 8mm stone.
How can we prevent further stones formation?
We also started potassium citrate to increase urinary citrate (check this article for the updated AUA guidelines for the medical management of kidney stones).
Renal Functional Reserve: Time for a Kidney stress test in clinical practice?
GFR varies under normal physiological conditions and during illnesses. A popular example is a low GFR in vegetarians and a higher GFR in consumers of large quantities of animal protein, even when they have a similar normal renal mass. It is not clear what the maximum GFR can be, but it can be approached with an acute animal protein load. One to two hours after an animal protein load, individuals with healthy kidneys will show a significant rise in their GFR independent of their baseline GFR. The difference between baseline and maximal (i.e. stress or peak) GFR is called the Renal Functional Reserve (RFR).
The GFR rises considerably during pregnancy. This physiological rise is multifactorial and is mainly attributed to increase in cardiac output and renal blood flow. It becomes apparent from the 1st month and peaks at 40% – 50% above baseline levels by the 4th or 5th month of pregnancy. This increase in GFR is referred to as renal hyperfiltration. The RFR is consumed as a part of adaptation to this physiological demand that occur during pregnancy. This was demonstrated by Ronco et al. They assessed GFR changes in pregnant women, with normal kidneys, before and after protein load. After acute protein load, all women had a significant increase in GFR. This rise was more in the first than in the last trimester. This finding explains, at least partially, renal hyperfiltration in pregnancy.
RFR allow for an increase in GFR during stressful conditions to ensure maintenance of adequate kidney function. When RFR is lost or fully utilized and the kidney insult continues, changes in baseline GFR and serum creatinine occur. After an AKI episode, creatinine and GFR may return to normal, displaying an apparent complete recovery of the kidney. Unfortunately, this recovery might be at the expense of reduction or loss of the RFR. In my opinion, without performing a kidney stress test to assess the RFR post-AKI, it will remain unclear whether the recovery from AKI was complete or was it just a biochemical recovery (reflected by creatinine level) at the expense of RFR utilization. Conceptually, recovering baseline GFR and creatinine level post-AKI without recovering the RFR should be labelled as new-onset CKD because it actually reflects an irreversible loss of nephrons/RFR. I have no evidence to support this, but I would hypothesize that these patients who lose their RFR post-AKI are the ones who were shown to progress to CKD in previous studies.
Assessment of recovery post-AKI: It will help to detect patients who are likely to progress to CKD.
Assessment of living kidney donors prior to donation: It is likely that a low RFR might increase the long-term risk of CKD during the post-donation period.
To assess the risk of AKI in patients undergoing contrast studies and high-risk surgeries.
Of course robust studies are needed to assess the diagnostic and the prognostic utility of RFR and kidney stress test in the clinical setting.
Obesity and CKD: How big is this?
How important is obesity to the field of nephrology? Perhaps obesity is the single strongest risk factor for CKD in the US and most of the developed world. While genetics are certainly important, obesity drives the diabetes epidemic and contributes significantly to the hypertensive burden in our population. But if obesity is this important, how can we best help our patients? Should nephrologists emphasize obesity along with our traditional targets (e.g. HbA1c < 7%, SBP < 130 or 140 mmHg, statin use, etc.)? Unfortunately, there is not a lot of data to guide us.
Attempting to look at obesity as a risk factor for CKD independent of diabetes or hypertension is challenging. However, there are a few studies that suggest an independent effect on CKD and its progression (Hsu, Cao). Whether or not "metabolically healthy" obese patients are at higher risk of CKD remains unclear (Hashimoto).
There are likely other mechanisms in obesity beyond diabetes and hypertension that are injurious to our beans (Rao). For example – increased abdominal pressure can activate RAAS and visceral fat itself can generate not just angiotensinogen but also inflammatory cytokines (such as leptin) which may stimulate renal fibrosis. Physiologic changes in obesity create glomerular hypertension, hyperfiltration, and glomerulomegaly. In a subset of these patients, for unclear reasons, overt glomerulosclerosis develops.
The effect of obesity on renal function was clearly reported in 1974 in four non-diabetic patients with severe obesity and nephrosis (Weisinger). The nephrosis and proteinuria resolved with significant weight loss during prolonged hospitalizations. Subsequent studies have also shown the resolution of glomerular hyperfiltration with weight loss.
The clinical and pathologic characteristics of obesity related glomerular damage have been described (Kambham). Notably, when compared to patients with idiopathic FSGS, obesity-related glomerulopathy demonstrates lower rates of true nephrotic syndrome as well as less, but certainly not insignificant, progression to ESRD. Importantly, clinical characteristics do not seem to differentiate between obesity-related glomerulomegaly with hyperfiltration and the development of obesity-related FSGS.
If obesity worsens renal function then how should we combat it? Data focusing on individual patient treatments in CKD is limited, with the majority of studies being small with short term follow-up. Weight loss is associated with a reduction in proteinuria but no clear change in GFR (Naveneethan). Bariatric surgery offers a therapy that can reliably produce significant weight loss, reduce or eliminate proteinuria, and improve diabetic and hypertensive control. Its effects on GFR however are hard to predict, especially given that creatinine often decreases post-surgery given the loss of lean body mass that parallels declines in adiposity. Likewise, the true risk of hyperoxaluria and worsened renal function in modern malabsorptive procedures is not well understood. The literature on bariatric surgery and diabetic nephropathy was recently reviewed here (Friedman).
How aggressive should we be regarding weight loss in our patients?
Is it enough to recommend diet and exercise or should we advocate for weight loss programs?
Should we prescribe medications such as orlistat or phentermine/topiramate?
Should we refer patients for consideration of bariatric surgery?
Hopefully the coming decades will clarify these questions.
I was asked to see 74 year old man with an acute on chronic kidney injury. He had 2 days of generalised lower abdominal pain and vomiting but no urinary symptoms or fever. His past history included advanced CKD, benign prostatic hypertrophy and a slow growing renal cell tumour under radiological surveillance. His vital signs were normal and he had mildly raised inflammatory markers. I ordered a CT KUB to exclude obstruction (it was a weekend and was no ultrasound service in the hospital). To my surprise this came back as showing emphysematous pyelitis. Interestingly there had been a hiss of air as he was catheterised for fluid balance monitoring – a fact I had dismissed at the time!
Emphysematous UTIs are gas forming infections of the urinary tract and can manifest as cystitis (gas within the bladder wall), pyelitis (gas within the collecting system) or pyelonephritis (gas within renal parenchyma or perinephric tissues). It is a relatively rare condition and there is a dearth of literature describing incidence. Diabetes and urinary tract obstruction are major risk factors, present in around 80% and 20% of patients respectively. Causative organisms are most commonly E. Coli and Klebsiella pneumoniae, with Candida being involved less frequently. Presentation is usually similar to acute severe pyelonephritis with fever, flank pain and vomiting. 50% of patients have an associated bacteraemia. Diagnosis is usually made by CT which shows the extent of gas within the urinary tract and any obstruction.
Treatment depends on the extent of infection. It ranges from parenteral antibiotics alone for patients where gas is limited to the collecting system with no obstruction, to percutaneous drainage of purulent material and antibiotics if there is abscess formation or extension of gas into the perinephric space, to nephrectomy in patients with diffuse gas and extensive renal destruction.
In the above case, the urine sample was initially reported as 'no significant bacteriuria' but subsequently grew a resistant E. Coli >1,000 - <10,000 cfu/ml. Urology felt that surgical intervention was not required as the renal parenchyma was not involved and he had no abscess formation. The patient completed 2 weeks of ertapenem and his renal function returned to baseline.
As someone who spends a lot of time signing off patients' results, I realise that 'no significant bacteriuria' is not the same as 'no growth', and in this case the difference was substantial. The wording of how we report things and how we interpret that is crucial.
A high index of suspicion is required to diagnose emphysematous UTIs and the most appropriate imaging modality should be considered. Ultrasound is generally the first line investigation for urinary obstruction in patients with acute kidney injury or febrile urinary tract infection due to high sensitivity for hydronephrosis, lack of ionising radiation and lower cost than CT. Ultrasound appearances in emphysematous UTIs can be difficult to interpret however: gas, calculi and calcifications are hard to distinguish and there is often variability in how they are reported. CT is able to precisely localise the presence of gas within the urinary tract and determine whether there is involvement of the renal parenchyma and perinephric tissues. It can also identify any concomitant pathology or alternate diagnosis e.g. renal calculi. CT is therefore preferable for diagnosis and subsequent severity staging.
Pneumaturia has been described as a presenting feature of emphysematous UTI. Other causes include vesicovaginal or vesicoenteric fistulae, renal tumour infarction and recent instrumentation. The unexpected air hiss when catheterising this gentleman was a warning of a more serious pathology and should prompt further investigation.
While the outcome of emphysematous pyelitis is better than that of pyelonephritis (which has a mortality of 18-70% depending on extent of involvement), it is still not a condition to be taken lightly.
Nephropoly: Urine Trouble, a winner of the inaugural 2015 ASN Innovations in Kidney Education Contest is now available at the link below. You will need to use a desktop to run this program. Below is a quick description from the creator Dorey Glenn. Check it out.
"Nephropoly: Urine Trouble is an educational web-based "board game" that aims to help medical students, residents, and fellows learn renal physiology. Players answer region specific multiple choice questions as they are filtered through the glomerulus and travel along the nephron. Topics are physiology-based, but draw on aspects of clinical nephrology when appropriate to highlight particular physiologic principles. The game has been designed to accommodate 1- 4 players, thus facilitating group learning when desired. A single player "study-mode" is also available. The design of Nephropoly promotes a fun, high-yield, physiology-focused review of renal physiology."
The complex interplay of calcium and phosphorus metabolism with intact PTH, vitamin D, and FGF-23 is one of the more difficult things to understand, and also one of the hardest concepts to teach to students, residents, and fellows. The May episode of the Washington University Nephrology Web Series helps you to understand this topic in 20 minutes, demonstrating normal physiology and then the abnormalities that develop in chronic kidney disease states.
In case you missed our April episode, which was a renal pathology teaching series on amyloidosis, you can find it here. Enjoy!


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The University of Washington is a public flagship research university based in Seattle, Washington, United States. Founded in 1861, Washington is one of the oldest universities on the West Coast and features one of the most highly regarded medical schools in the world.
Founded 4 November 1861, the University of Washington is one of the oldest state-supported institutions of higher education on the Pacific coast. The University is comprised of three campuses: the Seattle campus is made up of sixteen schools and colleges whose faculty offer educational opportunities to students ranging from first-year undergraduates through doctoral-level candidates; the Bothell and Tacoma campuses, each developing a distinctive identity and undergoing rapid growth, offer diverse programs to undergraduates and to graduate students.


Mothers Day celebrations are going to begin on Monday……..
It's that time of year again, when we take the time to honour and thank our Mums, enjoy being Mums ourselves and reflect on the delightful influences of Mothers in Society all around the world.
I have friends (a couple to be precise) who celebrate – 'the birthday week'. They have the theory that one day just really isn't enough time to enjoy the celebration of their own birth. It's really is such a great idea, one day doesn't feel like enough time to really reflect over the bigger picture of any celebration let alone one that takes 9mths of physical preparation. So last year we decided to go one more and make the Months of April and May- Our Mothers day reflection months.
Through April and May, we will be doing many things at the studio to remember mothers, thank mothers and of course document them. And to start it all off, on Monday we will be starting the popular Super Cute Mothers day Facebook Competition- allowing anyone who comes into the studio in April and May to go into our online poll of the super cutest Mum 2013.
Last years lucky winner Rebecca, received a gorgeous hamper of personalised handmade Items that starred her and her little fellow from their photo shoot. This years prize and details will be announced on Monday 15th April 2013.


The Tim Burton exhibit opened this weekend at LACMA and was summarily panned by the LA Times.
In an art museum, do we really need to see baby Penguin's black-wicker pram from "Batman," Catwoman's shredded polyurethane cat suit or the fluffy angora sweater used as a fetishistic prop in "Ed Wood"? Such dark or peculiar items are often outward signs of their character's concealed inner life; but that's catalog essay interpretation, not exhibition material. You get the feeling they're only here to satisfy the paying movie fans. Sometimes the display looks like the Arclight Cinema lobby on steroids. Toss in assorted puppets and a few toy-like sculptures, such as a suspended flying-saucer carousel illuminated by black-lights, and the quotient of celebrity self-indulgence climbs.
LA Weekly's Lena Lecaro was a little more forgiving.
The show is a wondrous experience, a walk inside the head of the dark, surreal fantasy genius featuring everything from movie props and get-ups (Catwoman and Edward Scissorhands costumes) to sketches for films such as The Nightmare Before Christmas and Alice in Wonderland to fine art inspired by or that influenced his work.
Burton explains the exhibit in his own words to the Wall Street Journal.
The biggest compliment I've gotten so far is from people that don't usually go to museums. It makes people realize that anything is possible. I think that one the things that made it acceptable is it's not something that was ever meant to really be…but I think the curators did a good job in sort of not making it to like it's great artwork but this is somebody's process. It's great to me to inspire people – to keep drawing, even if they think they can't do it – to show that you don't have to be the greatest artist in the world – if you like it, that's the important thing.


text:
Q: Removing Debian package automatically masks systemd service - causes a systemd warning I booted a Debian unstable container.  Early on, systemd inside the container shows rsync.service: Cannot add dependency job, ignoring: Unit rsync.service is masked.
I determined that rsync.service was masked automatically because the rsync package was removed.  Re-installing the package unmasked it again.

*

*Is there documentation for this behaviour?

*What is the conflict that causes systemd to warn, when faced with this behaviour of Debian?

*I'm pleasantly surprised to see that this behaviour somehow detects if I masked rsync while it was installed, and avoids unmasking it automatically if I remove and reinstall rsync.  How is this implemented??  Are there any more subtle limitations to it?

Discovery of automatic masking on package removal
I knew that rsync had originally been installed, but was now removed.  I removed the mask, and was left with this:
$ sudo systemctl status rsync
● rsync.service - LSB: fast remote file copy program daemon
   Loaded: loaded (/etc/init.d/rsync; generated; vendor preset: enabled)
   Active: inactive (dead)
     Docs: man:systemd-sysv-generator(8)

$ # reset status of all systemd services
$ # DO NOT TRY THIS COMMAND INSIDE A REAL, NON-CONTAINER SYSTEM...
$ # IT DOES NOT GO WELL.
$ sudo systemctl isolate default.target

$ sudo systemctl status rsync
● rsync.service - LSB: fast remote file copy program daemon
   Loaded: loaded (/etc/init.d/rsync; generated; vendor preset: enabled)
   Active: active (exited) since Wed 2017-06-07 11:35:27 BST; 1s ago
     Docs: man:systemd-sysv-generator(8)
  Process: 432 ExecStart=/etc/init.d/rsync start (code=exited, status=0/SUCCESS)
   CGroup: /machine.slice/machine-unstable.scope/system.slice/rsync.service

Jun 07 11:35:27 unstable systemd[1]: Starting LSB: fast remote file copy program daemon...
Jun 07 11:35:27 unstable systemd[1]: Started LSB: fast remote file copy program daemon.

This output is misleading.  Debian's /etc/init.d/rsync was not starting rsync --daemon, because I had not changed the default RSYNC_ENABLE=false in /etc/default/rsync.  (The init script itself would exit silently in this case; however I believe a systemd boot would show a starting message for it, similar to the log messages shown above).  So the masking was serving a useful purpose here.
(The reason /etc/init.d/rsync remains when the package is removed, is that  initscripts are considered to be user-editable configuration files)
It turns out that if I install rsync again, rsync.service is unmasked.  If I remove it, rsync.service becomes masked again.
I'm pleased to say that if I install rsync, mask it, then remove and reinstall rsync, rsync remains masked.
If I use apt-get remove --purge rsync to completely remove it, including residual configuration files, then the mask is removed.
Since I have etckeeper installed, I noticed that complete removal also removes
/etc/systemd/system/multi-user.target.wants/rsync.service, as well as removing the mask (/etc/systemd/system/rsync.service -> /dev/null).  Neither of these files were owned by the package (dpkg-query -L rsync), so it looks like these removals are caused by a package script.
Software versions
Up to date Debian unstable container.  This question was asked soon before the release of stretch.
Host used systemd-container version 231-15.fc25.
More context for systemd message "ignoring: Unit rsync.service is masked"
$ sudo systemd-nspawn -b -D unstable
Spawning container unstable on /home/nspawn/unstable.
Press ^] three times within 1s to kill container.
systemd 232 running in system mode. (+PAM +AUDIT +SELINUX +IMA +APPARMOR +SMACK +SYSVINIT +UTMP +LIBCRYPTSETUP +GCRYPT +GNUTLS +ACL +XZ +LZ4 +SECCOMP +BLKID +ELFUTILS +KMOD +IDN)
Detected virtualization systemd-nspawn.
Detected architecture x86-64.

Welcome to Debian GNU/Linux 9 (stretch)!

Set hostname to <unstable>.
Failed to install release agent, ignoring: File exists
rsync.service: Cannot add dependency job, ignoring: Unit rsync.service is masked
[  OK  ] Started Dispatch Password Requests to Console Directory Watch.

A:
Is there documentation for this behaviour?

It is written down.  The pointer as to why this is implemented is found in a commit message to a file which was since moved elsewhere...

I'm pleasantly surprised to see that this behaviour somehow detects if I masked rsync while it was installed, and avoids unmasking it automatically if I remove and reinstall rsync. How is this implemented?? Are there any more subtle limitations to it?

Look hard, and you can still find the source history.  It links to an issue, which confirms that masking is used to handle the system V initscripts as best as possible under systemd.
Tangent: there's an unimplemented proposal which would remove the need for this, #749400 - dh_installinit: disable init scripts on removal of package.  Not that it's an unambiguously good idea.  IIUC, it loses track of whether the script was enabled by the user.  (Note this is a separate setting for each runlevel, in system V init).
The clue to this was in the package script, which I found at /var/lib/dpkg/info/rsync.postrm.
## from /usr/share/debhelper/autoscripts/postrm-systemd :

if [ "$1" = "remove" ]; then
    if [ -x "/usr/bin/deb-systemd-helper" ]; then
        deb-systemd-helper mask rsync.service >/dev/null
    fi
fi

What this does is documented in man deb-systemd-helper.  'The "mask" action will keep state on whether the service was enabled/disabled before and will properly return to that state on "unmask".'  It is also commented in  rsync.postinst:
## from /usr/share/debhelper/autoscripts/postinst-systemd-enable :

# This will only remove masks created by d-s-h on package removal.
deb-systemd-helper unmask rsync.service >/dev/null || true

Fedora Linux (version 25) doesn't implement this behaviour.  Arguably because they don't support system V init and had a policy to completely remove the old-style init scripts.  I don't know how they handled this issue during the transition... but they could have ignored it without causing any functional problem.

What is the conflict that causes systemd to warn, when faced with this behaviour of Debian?

In the general case, masking an enabled service seems a bit suspicious, perhaps?
It looks like the rpm based distributions don't / didn't try to preserve the enabled status of initscripts.  Because they run checkconf --del on removal.  https://www.cyberciti.biz/faq/centos-rhel-suse-rpm-see-installation-uninstallation-scripts/

The modern Fedora rpms have equivalent-looking code
$ rpm -q --scripts rsync
...
    # Package removal, not upgrade
    systemctl --no-reload disable --now avahi-daemon.socket avahi-daemon.service > /dev/null 2>&1 || :
...

I looked at this as I noticed removing rsync-daemon doesn't remove  /etc/systemd/system/multi-user.target.wants/rsyncd.service.  Because systemctl disable does not currently remove symlinks if they point to a file which has already been removed.  This is a bug specific to the rsync package: the service file is in package rsync, but the rpm scripts referring to the service are in package rsync-daemon.

redpajama_set_name: RedPajamaStackExchange


text:
What Breakthrough Did Copernicus Make In 1543
What breakthrough did Copernicus make in 1543? A. He realized that the earth is round. B. He realized that planets and stars rotate. C. He realized that the moon is not a planet. D. He realized that planets rotate around the sun. 3. In 1609, Galileo developed the telescope. What did he.
That breakthrough. make a different assumption," Prof. Aldana said. "Let's assume that they had historical records and they were keeping historical records of astronomical events and they were.
To make sense of a seemingly apocalyptic. stare directly at the sun during an eclipse. Copernicus was able to observe at least four solar eclipses during his life, often through a camera obscura.
Nicolaus Copernicus Essay. The Astronomer, Nicolaus Copernicus. before, which was that the sun and other planets revolved around Earth. Copernicus was a genius of his time and had a breakthrough in astronomy. He is known as the initiator. In 1543 Nicolaus Copernicus published On the Revolutions of the Heavenly Spheres, a book which.
Nov 03, 2020 · Copernicus's lifetime (1473 – 1543) spanned what was perhaps the most momentous 70-year period in Western history. During the year of his birth, the freshly invented printing press was spreading to all corners of Europe. When Copernicus was 19, a Genoese explorer named Christopher Columbus sailed the Atlantic for a recently united Spain.
Albert Einstein I Do Not Know "I do not know with what weapons World War III will be fought, but World War IV will be fought with sticks and stones." – Albert Einstein. This quote (or at least a version of it) dates back to the. I, on the contrary, developed so slowly that I did not begin to wonder about.
Copernicus cites Martianus Capella, who put forward this model in his Marriage of Philology and Mercury, probably more through mixing up his sources than due to any great conceptual breakthrough [NOTE] p 333, volume 2, Martianus Capella The Marriage of Philology and Mercury trans. Stahl and Johnson, (Columbia, 1977).
After many years of meticulous calculation, Nicolaus Copernicus (1473-1543) rejected the cosmology of Aristotle and Ptolemy and showed that the earth was a planet revolving around the sun. But he was a prudent man, not letting his work be published until just before his death. they began to be harnessed. It was the breakthrough needed, and.
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Planet Moon did so in 1/12 year – one month. ancient astronomers might not have treated the moon as a typical planet. With Copernicus's heliocentric astronomy, published in 1543, the moon ceased to.
Get an answer for 'What did Nicolaus Copernicus contribute to science? Did he futhered human knowledge of the solar system or did he futhered human knowledge of.
– Nicolas Copernicus Nicolas Copernicus 1473-1543 Physics February 8, 2000 Nicolas Copernicus Nicolas Copernicus 1473-1543 Copernicus was born in Poland in 1473, he started his education at Cracow University. There he studied mathematics and optics. The Scientific Revolution was the breakthrough that led into the start of the Enlightenment.
The latest breakthrough in engineering would make many lives better, the scientists were sure. What breakthrough did Copernicus make in 1543? God doesn't exist.
Prior to Galileo's time, people did not run. opinions in about 1543, just before his death. Galileo studied Copernicus' work and in 1609 a stroke of real good luck befell him. He heard of an.
The breakthrough that won for Marshall the Nobel Prize. such as planetary positions. So why replace it? Copernicus's heliocentric model did no better than predicting celestial events than the.
In May 1543, Nicolaus Copernicus, a Pole living in Prussia. again pushed and passed by the GOP-led White House and Congress last month. Still, why did Americans swallow such empirically false.
Start studying science chapter 25 (incomplete). Learn vocabulary, terms, and more with flashcards, games, and other study tools.
In just six weeks, the planet Mars will make its closest approach to Earth since. ultimately making the Greeks' explanation quite useless. In 1543 the great Polish astronomer Nicolaus Copernicus.
even the tower where he did his stargazing almost 500 years ago has been carefully preserved. One thing has been missing: Copernicus himself. The people of Frombork have long known that Copernicus.
Mars will be 97 million miles closer to Earth and shine 10 times brighter than it did at the start of this year. Artist's concept of Comet Siding Spring approaching Mars, shown with NASA's orbiters.
Using this definition I'd make the case that much of the learning. false beliefs that can lead to irrational decisions. Copernicus published his thesis that the Earth revolves around the sun in.
What breakthrough did Copernicus make in 1543?. No, Copernicus died of a stroke in 1543 and was in good stead with the Catholic Church at the time. Where did nicolaus Copernicus die?
The article entitled "The Management Revolution" is published in conjunction with. At first, the publication of Copernicus's thesis in 1543 received little attention. As it gained momentum, the.
That breakthrough. don't know Copernicus's name. You know the pope was giving him this charge, but the person who did it? You don't know his or her name." University of California – Santa Barbara.
Nicolaus Copernicus's Life and Work – Nicolaus Copernicus was a polish astronomer and a cleric. At the age of ten his father died and his uncle took him in along with his brothers and sisters. His uncle wanted to make sure he had the best education possible.
This was a time when the common belief held was that the earth was the centre of the universe and did not move. next stage of observation after Copernicus and Galileo? What was needed was someone.
The real breakthrough that ultimately led to the acceptance of Copernicus' theory was due to Galileo, but was actually a technological rather than a conceptual breakthrough. It was Galileo's refinement and clever use of the telescope that persuaded people that the moon was a lot like the earth, and in some ways, so were the planets.
The people of Frombork have long known that Copernicus died somewhere around here in 1543, but the failure of their ancestors to record exactly where he was buried has fueled one of the most.
Achievements Of Blaise Pascal Both of these enhancements lead to a brand-new GPU architecture, and in celebration of Blaise Pascal's achievements in the 1600s, Maxwell's successor becomes "Pascal". A demo board (seen above) was. He demonstrated that the space at the top of a barometer is a vacuum. This quiz and corresponding worksheet will help you gauge your understanding
A few of those pinpricks of light, however, did not obey the rules. but changed his mind. The big breakthrough came in 1543 when Nicolaus Copernicus published On the Revolutions of the Celestial.
Nicolaus Copernicus (1473 – 1543) was a Polish mathematician, astronomer and lawyer. During his life, most people believed in the Geocentric model of the universe, with Earth at the centre and everything else rotating around it. Copernicus created a new model, where the sun is at the centre, and Earth moves around it on a circle.
Accounting for the observed phenomena had long been a primary goal of astronomy. When Copernicus published De revolutionibus orbium coelestium (On the Revolutions of the Heavenly Spheres) in 1543, it appeared with an anonymous preface now attributed to its publisher, the German theologian Andreas Osiander. In an attempt to forestall criticism.
There's a Copernicus museum and a Copernicus altar; even the tower where he did his stargazing almost 500 years ago has been carefully preserved. died somewhere around here in 1543, but the.
How then did Motorola, Nokia, and RIM end up in such dire straights. For thousands of years we believed the Earth was flat. When Copernicus proved otherwise in 1543, we fought against the idea for.
The Scientific Revolution: Timeline, Breakthroughs & Effects. Revolutions of the Heavenly Spheres by Nicolaus Copernicus in 1543. This was the first major work to propose that the Earth.
In the early 1500s, when virtually everyone believed Earth was the center of the universe, Polish scientist Nicolaus Copernicus proposed that the planets instead revolved around the sun.
Rethinking assumptions That breakthrough led him to question. but you don't know Copernicus's name. You know the pope was giving him this charge, but the person who did it? You don't know his or.
Feb 26, 2006 · It Could Be the Head Of Nicolaus Copernicus. The people of Frombork have long known that Copernicus died somewhere around here in 1543, but the failure of.
Oh, and he did this all before he was 30. On the fabric of the human body), though he faced quite a bit of backlash when he published it in 1543. Five hundred years later, museums, medical groups.
October 8, 2019 @ 5:27 am · Posted in Science 101 · Author:admin


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Boynton Middle School
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A boy called bat
Arnold, Elana K.
"When his veterinarian mom brings home a stray baby skunk that needs rehabilitation before it can be placed in a wild animal shelter, Bat, who has austim, resolves to prove that he is up to the challenge of caring for the skunk permanently"--OCLC.
View cover image provided by Mackin
Due 01/30/20
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Can you survive storm chasing? : an interactive survival adventure
Raum, Elizabeth.
The creeps : curse of the attack-o-lanterns
Schweizer, Chris.
Diary of a wimpy kid : double down
Kinney, Jeff.
The pressure's really piling up on Greg Heffley. The only thing he's good at is playing video games, but his parents want him to broaden his horizons by doing something-anything!-else. When Greg finds an old video camera in his basement, he thinks he may have discovered just the thing to prove he's got big-time talent. With the help of his best friend, Rowley, Greg hatches a plan to make a scary movie and to become rich and famous in the process. Is it a smart plan or a recipe for trouble?.
EDM : electronic dance music
Godard, Julie K.
"Electronic dance music (EDM) has grown from a small niche genre limited to small clubs to a billion-dollar industry popular worldwide. EDM artists use software and digital instruments to create the widely varied dance music that is popular today. This book provides information on the origins of EDM, the genre's biggest stars and most elaborate international festivals, and the techniques and equipment that are commonly used to entrance audience"--Back cover.
KIB
Explorer : the hidden doors
Kibuishi, Kazu.
Poblocki, Dan.
Poppy Caldwell is an orphan who keeps seeing a figure standing behind her in the mirror at the group home where she lives, but she does not associate this ghost with the letter that mysteriously appears in her file, claiming to be from a long-lost aunt, and inviting her to Larkspur House--and she is just one of five children who find themselves gathered in this strange house with a deadly past, and apparently no intention of letting the children escape.
Telgemeier, Raina.
In graphic novel form, Raina Telegmeier relates her struggles with stress and anxiety as a child.
Dearmont, Christina, author. aut.
Hip hop began as a form of expression for black Americans living in urban areas, but today has spread throughout the world.
Knots : a step by step guide to tying loops, hitches, bends, and dozens of other useful knots
Burton, Kenneth S.
Mirror, mirror on the wall : the diary of Bess Brennan
Denenberg, Barry.
In 1932, a twelve-year-old girl who lost her sight in an accident keeps a diary, recorded by her twin sister, in which she describes life at Perkins School for the Blind in Watertown, Massachusetts.
Applegate, Katherine.
Ivan is an easygoing gorilla. Living at the Exit 8 Big Top Mall and Video Arcade, he has grown accustomed to humans watching him through the glass walls of his domain. He rarely misses his life in the jungle. In fact, he hardly ever thinks about it at all. Then he meets Ruby, a baby elephant taken from her family, and she makes Ivan see their home-and his own art-through new eyes. When Ruby arrives, change comes with her, and it's up to Ivan to make it a change for the better.
Raiders' ransom
Diamand, Emily.
In 23rd-century Great Britain, where climate change has caused vast flooding, the piratical raiders kidnap the Prime Minister's daughter and thirteen-year-old Lilly Melkun, an English fishergirl, takes her seacat on a daring rescue attempt, with a mysterious talking jewel from a past computer age tucked in her belt as ransom.
Korman, Gordon, author.
Chase does not remember falling off the roof; in fact, he does not remember anything about himself. When he gets back to middle school, he begins to learn who he was through the reactions of the other kids--trouble is, he really is not sure he likes the Chase that is being revealed. Can he take the opportunity amnesia has provided and restart his life?.
Sci-Fu
Mercado, Yehudi.
"One night, while making a mixtape for his crush, Wax scratches the perfect beat and responds to an interstellar challenge that transports him and the entire block to the robot-filled planet of Discopia. Mistaken by the locals for a master of the futuristic, sound-bending martial art Known as Sci-Fu, Wax finds himself on the wrong side of a showdown against the Five Deadly Dangers and their leader, Choo Choo"--Back cover.
Scrawl : a novel
Shulman, Mark, 1962-
When eighth-grade school bully Tod and his friends get caught committing a crime on school property, his penalty--staying after school and writing in a journal under the eye of the school guidance counsellor--reveals aspects of himself that he prefers to keep hidden.
Skeleton Key : [the graphic novel]
Horowitz, Anthony, 1955-
On a routine mission at the Wimbledon tennis championships, reluctant teenage spy Alex Rider gets caught up in Chinese gangs, illegal nuclear weapons, and the suspect plans of his Russian host, General Sarov.
From sixth grade through tenth, Raina copes with a variety of dental problems that affect her appearance and how she feels about herself.
Riordan, Rick.
Demigod Percy Jackson, still with no memory, and his new friends from Camp Jupiter, Hazel and Frank, go on a quest to free Death, but their bigger task is to unite the Greek and Roman camps so that the Prophecy of Seven can be fulfilled.
"I won't describe what I look like. Whatever you're thinking, it's probably worse. "August (Auggie) Pullman was born with a facial deformity that prevented him from going to a mainstream school--until now. He's about to start 5th grade at Beecher Prep, and if you've ever been the new kid then you know how hard that can be. The thing is Auggie's just an ordinary kid, with an extraordinary face. But can he convince his new classmates that he's just like them, despite appearances? R. J. Palacio has written a spare, warm, uplifting story that will have readers laughing one minute and wiping away tears the next. With wonderfully realistic family interactions (flawed, but loving), lively school scenes, and short chapters, "Wonder" is accessible to readers of all levels. "From the Hardcover edition.".
Lexile ™ Metametrics, Inc.


Truth and Reconciliation Commission of Canada. TRC FIndings. Retrieved from: http://www.trc.ca/websites/trcinstitution/index.php?p=890 on February 20, 2016.
This entry was posted in Resources and tagged TRC, Truth and reconciliation commission.


February has us running our normal schedule of classes – Yay! Please note that Thursday 6 Feb is Waitangi Day, therefore no Thursday classes this coming week. Jeffree is running a FREE Meditation Session this Tuesday 4th 7.30-8.30pm to give you a taste of what to expect in his 3 week Meditation Course which starts Thursday 13 Feb from 7.30-9.30pm.
Jeffree's easy flowing style will help you still the mind, feel more relaxed and happier. His beautiful music gently guides you inwards – bliss!
An inspirational class for yogini's and yoga teachers. Swami Ratnamurti has a wealth of knowledge and has trained many students to become yoga teachers.
This class includes postures, body & hand mudras, pranayama, chakras and deep relaxation with yoga nidra. You will feel sublime and happy!
Let your creative juices flow as you explore the possibilities and potential of living in a different way in a hands on Vision Board Workshop.
Clarify and set your goals for 2014, Explore your Souls' Desires, Create a Visual Picture of your Wishes and Dreams, Focus on and Manifest your Deepest Desires, Open up the doorway to a new way of being and weave new pathways to create your ideal life – one which satisfies your Soul.
Cost: $30 Or, bring a friend and pay $50 between you. Light refreshments are provided.
A 2 day workshop with certified and licensed Heal Your Life Workshop Leader – Liz Weatherly.
Over an empowering weekend understand the connection between our beliefs and how we experience life; learn how we can use this connection to find and bring about a life that is happy and fulfilled: experience practical and useful techniques and ideas for your everyday life.
These are $110 for the 6 weeks – current concession card holders and AP members can attend.
And finally – two dates for March.


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Super Sunday: Dr. Malevolence and Injectia
Sunday 19th January 2014 @ 4:00 AM
Dr. Malevolence
Dr. Janessa Tindall will show them all! They laughed at her theories about a connection between the human mind and teleportation. Tindall turned to criminal backers to fund her projects. She still failed. Her attempt to prove her findings resulted in a terrible disaster and dozens were killed. Tindall was sent to prison. But her criminal backers did not forget her, they broke her out of prison and put her to work as their own weapon designer. Tindall killed them all for their insolence and went on to be her own criminal, holding cities hostage and building rampaging robots. Nobody would ever laugh at her again.
The state of the Female Mad Scientist in fiction is one that could use some improvement (here is an article on the topic). Heck, women are underrepresented as regular scientists too, and not just in fiction. In the real world even. But given my belief that how we shape our fiction can affect how we see our world, it is my duty to pump out some lady science-types. And this is villains year, both of today's villains are Mad Scientists Who Aren't Dudes. Dr. Malevolence here is, I guess, more of a standard Crime Scientist that you've gotta have if you are dealing with superheroes.
Injectia
Some people might make a poor life choice in a fleeting moment after having a bad idea, but Tara Jensen was truly devoted to her bad idea. Removing her left arm, Tara has replaced the limb with a giant syringe. But the device is more than a simple needle, it contains high-tech workings that allow her to work with chemicals and formulas and viruses, giving her various ways to utilize her new appendage. Naturally, Tara has styled herself as the supervillain Injectia and embarked on a career of crime with no end in mind greater than continuing her messing around with chemicals and viruses. She has become a primary target for the government's hero, the Securer.
Not much to add. Another mad scientist, this one perhaps more of the kind of obsession with her interests than a desire for revenge or anything. I think Injectia would barely care about people who have wronged her or who are trying to capture her. She's just really interested in her science and doesn't care who she hurts in the process.
Permalinked: Super Sunday: Dr. Malevolence and Injectia
Tagged: character sketch, Super Sunday!, Supervillain Sunday
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Nexted: Jan 20 Phone Guys Comic


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Research Notes: The Biggest (Earnings) Losers
Looking for value in the big sell-offs — and not seeing much
Welcome to Overlooked Alpha by Vince Martin and Joe Marwood. Subscribe below to get our best investing ideas direct to your inbox every Sunday morning:
One strategy in a nervous market — and the NASDAQ Composite is down almost 5% Thursday as I write this — is to look at the biggest decliners, for stocks where market sentiment has either exaggerated longer-term risks or, in some cases, created them out of whole cloth.
This is not the only strategy, of course; focusing more intently on quality in a downturn is another way to go. But in a big-time downturn — 2009 being the best recent example, and Q4 2018 another — it's the riskiest, most speculative and sometimes even kind-of-junky plays that provide the biggest returns when the market bounces back. (And let's try and remember — it always bounces back, even if not all of the stocks in the market do the same.)
The problem with this strategy, even after a 3-5% sell-off in major indices today, is that most of the biggest decliners look like they should be the biggest decliners. We covered this in our best pick so far, a short of Carvana (CVNA). CVNA — down 78% from its highs when we published, and as of this writing another 40% since — has performed a near-perfect representation of the old saw about how a stock falls 90% (it drops 80% and then gets halved).
We've been cautious about this market literally from our first post. We still are. One reason to stay cautious now is precisely that so many of these decliners really don't look that cheap. Some, in fact, still seem expensive.
Focusing on the most recent earnings reports, the same sense holds. There do seem to be some opportunities for long-term value, but the market's reaction to these earnings reports — even when that reaction appears rather extreme in terms of share price moves — looks to be logical.
In even the best-case scenario, we're probably heading into a "new normal" in terms of valuations for growth stocks in particular, and even the biggest growth stocks. As we wrote in our first post, we'll stay invested, if cautiously so, and try and take the long view. But as this post, and most of our due diligence suggests, at the very least buying opportunities are not easy to find, and for those that exist, there's no need to rush in.
A look at a few big declines, in no particular order:
Teladoc Health (TDOC)
Imagine being dead-on right about the novel coronavirus pandemic at the start of 2020, picking five of the stocks that proved to be the biggest winners — and being down on an equal-weight basket 28 months later:
And, man, at some point these have to bottom, right? Zoom Video Communications (ZM) looks a little bit tempting. I owned Amazon (AMZN) at a higher price in the past, and I'm intrigued at $2,500. (I don't love the "hey, you're getting the retail business for free!" argument; rather, I wonder just how much cost Amazon can pull out simply by focusing on profits, which it seems like the market is telling it to do.)
Even Teladoc, perhaps the biggest loser of the pandemic winners (TDOC stock now is down 87% from its February 2021 high) has a case. Indeed, the stock had gained 18% from its post-earnings close (admittedly following a 40% decline that day), before Thursday's sell-off interrupted the rally. Perhaps more incredibly, TDOC is down more than half since Jan. 1, 2020 (though the dilution from the utter disaster that was the Livongo deal obviously is a key factor in that underperformance).
There's certainly a way for bottom-timing to work here. Looking to 2022 guidance, TDOC now trades at less than 3x revenue, and ~28x Adjusted EBITDA. The issues cited by management at BetterHelp, the mental health business, seem legitimate, rather than excuses.
Teladoc cited lower yields in online marketing spend; struggling rival Talkspace (TALK) has done the same for several quarters, focusing specifically on elevated keyword costs for several quarters. Teladoc attributed the rise in costs this quarter to competition from startups, and that's logical; those private companies (and there are several) in this funding environment are in desperate "grow or die" straits. Some of those startups, as management alluded to, really do look like online pill mills.
That said, TDOC isn't an obvious, screaming buy here. Disrupting the US healthcare system in any way is a difficult endeavor; outside of BetterHelp, there's a lot to prove. The fundamentals are fine, as far as it goes, but the Adjusted EBITDA figure is inflated by the exclusion of stock-based comp: the annual run-rate for that expense in Q1 is equal to the entirety of full-year Adjusted EBITDA guidance at the low end.
Exclude dilution and TDOC is unprofitable — and still valued at $7 billion. I can see why investors stepped into the decline, but I'm not willing to be one of those investors just yet.
Accolade (ACCD)
ACCD appears to be the biggest loser of earnings season so far: the stock was halved after its fiscal Q4 report last week. The "healthcare concierge" provides services for employees, provided by employers, to manage and understand benefits and the broader healthcare system. The company went public in 2020 at $22, closed its first day just shy of $30, touched $55 last June, and now is barely above $6.
The story with the Q4 report was hugely disappointing guidance: Accolade expects revenue growth of just 13% to 18% this year, below expectations. The company also is losing Comcast, which not only was its largest customer but its first customer.
But ACCD's decline into earnings also highlights a huge error that the market made: using elevated price-to-sales multiples for companies without SaaS gross margins. Accolade's adjusted gross margin in FY22 was just 46.5%, and a Wells Fargo analyst bearish on the stock before earnings projected the figure would top out in the mid-50s.
Yet, at the highs, ACCD was trading at a forward P/S multiple around 11x — the equivalent of an 80% GM SaaS business trading at nearly 20x. That kind of multiple, even in a bull market, should be reserved only for the highest-quality names.
The market made the same mistake with EV/revenue with names as disparate as Chewy (CHWY) and Twilio (TWLO), where EV/GP multiples got as high as 40x. Even now, ACCD trades at more than 2x FY23 revenue guidance, while the company still is guiding for -10% to -11% Adjusted EBITDA margins.
To be fair, it's at least possible to see a bull case here. If ACCD was like TWLO at the highs, perhaps it can echo that stock at the lows: TWLO got dumped mercilessly back in 2017 when Uber (UBER) diversified its business, and that sell-off proved to be a huge buying opportunity. Accolade reduced its long-term growth target, but still aims ~20% annualized top-line growth after FY23; the current valuation is more palatable in that context.
Still the declines here, both after earnings and over the past 12 months, at the least seem merited. Again, we're not seeing a screaming buy or a market overreaction here.
Netflix (NFLX)
I detailed my thoughts on the stock elsewhere, and the hinge here really comes down to content costs. Assume current cash spend = normalized content cost and the stock is not cheap. Use amortized content costs and it is.
As is usually the case (in life, not just in investing), the truth is probably somewhere in the middle — and, measuring content costs between cash cost and amortization expense, Netflix stock is fine, but not really compelling. (We're getting repetitive here, yes.)
One interesting aspect here, however, is that it does seem Netflix is going to tighten its belt. That's going to be true with content (the spending on stand-up comedy, in particular, was absolutely ridiculous) and, as The Information reported (paywalled article), it will be true in terms of employee salaries as well.
We don't really know how much fat there is to cut in Big Tech. Anecdotally, it seems potentially significant. (The "why the @#$#$! does Twitter (TWTR) need 8,000 employees question that went around social media after the Musk buyout doesn't seem to have a good answer.) As with Amazon, there is a scenario where margins materially improve simply because these tech companies have to start acting like grown-ups.
But at these valuations — Netflix still has an enterprise value near $100 billion — perhaps the best trade on that thesis is to find a way to short Bay Area/West Coast housing.
Chegg (CHGG)
CHGG seems like a classic, "yeah, this is probably too cheap long-term, but why I am buying now?" case. Here, too, the stock isn't that cheap: reduced guidance post-Q1 suggests an EV/EBITDA multiple around 13x. And as with NFLX and TDOC, investors do have to wonder if the long-term case has been materially changed.
At the same time, even that reduced guidance is ~double FY19 results. Chegg has a dominant competitive position. College enrollments may see some pressure, but I'm skeptical the higher education model gets blown up any time soon. Yes, Chegg has literally become synonymous with cheating, but worrying about future generations is precisely how so many of us missed out on the multi-baggers in the oil and gas space
One thing to remember is that a business like Chegg is probably to some degree counter-cyclical. Amid the "jobless recovery", for-profit education stocks were among the best investments in the entire market from 2010 to 2013 (or so, going off memory there) before the Obama Administration blew up their business model. Chegg CEO Dan Rosensweig said on the Q1 call that an estimated 1 million students have chosen to "forego or postpone higher education over the last two years." A recessionary environment, and a decline in jobs, is good news for enrollment, and thus a potential tailwind for Chegg.
In a market that a) calms down a bit and b) comes around to accepting a recession as likely/inevitable CHGG probably at least finds a bottom. Are we at all intrigued by selling a January 10 put for a 7% return (~12% annualized)?
Shopify (SHOP)
SHOP is down 13% as of this writing, and the report highlights the key themes around this earnings season for tech.
On the bullish side, management teams need to adapt to the new environment. We saw this with Amazon, which overbuilt facilities. We see this with Shopify, whose Deliverr acquisition is raising the same fears. Lyft (LYFT) had an earnings call so bad (here's a great thread on it) that it was ridiculed by analysts, FinTwit, and CNBC alike for the tone-deafness of increasing investments when the market is screaming for profitability. Etsy (ETSY) clearly took its sellers for granted, and now, with far less leverage, is going to have to make some adjustments.
Long-term, this isn't a bad thing. I do think Amazon will figure it out. Netflix, probably. Shopify, maybe (we don't really know what Tobias Lütke looks like as CEO in an environment where the wind isn't blowing stiffly at his company's back). Lyft, probably not.
But we circle back to where we started. It's not as if the market is pricing in these lower normalized growth rates going forward. Shopify still has a market cap in the range of $55 billion. It trades at ~85x forward EPS estimates — and those estimates are coming down over the next few weeks.
An investor can reasonably believe that tech companies are going to react to the shellacking their stocks are taking, and understand that the days of focusing almost solely on revenue are over. (Anyone, whether on Twitter, Substack, Seeking Alpha, or in a sell-side report, using EV/revenue as a key metric right now will be mocked mercilessly. EV/revenue as a valuation method is done for years until we start this madness all over again.)
An investor can also believe that, particularly for these pandemic winners, the "slowing" year-over-year growth rates ignore the multi-year trend and the difficult comparisons. On both fronts, I'm one of those investors.
The problem remains, however, that such a thesis has to be paired with an argument that, fundamentally, the cost savings (whether in the P&L or the cash flow statement) and/or an eventually disproven apprehension about the "end of growth" will drive upside in the stock.
And that's where we keep running into problems. An investor can look at the operating results and environment and believe "it's not as bad as sentiment seems to suggest." But these stocks, even the big decliners, aren't yet priced to where that sentiment is — even after a pretty ugly session Thursday.
As we said up front, we started this project cautious. We remain so.
Disclosure: As of this writing, Vince Martin has no positions in any securities mentioned.
It's a joke. Honestly.