On Page Optimization is an integral and important part of SEO. On-page Optimization is the process of modification of various elements in a Web pages such as keyword density, html errors, html optimization, URL, Meta tag, ALT Tags, title, heading, XML Site Map so that search engine spiders could easily locate the Web pages.
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Anchor text :— Play a vital role in getting the higher ranks with all the major search engines.
Significance of keywords :— To optimize your website, it is better to keep in mind that using the selected keywords in the domain name is the initial and vital step.


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What qualifications have you got? from whom do you purchase necessary drugs in elizabethan times 1. This weekly competition is open to residents of the UK, Channel Islands, Isle of Man and Republic of Ireland aged 18 years over, except for employees of Telegraph Media Group Limited, their agents or anyone else professionally associated with the competition. nexium 40 mg en espa㰿l "I'm sure in some cases we have kept companies alive for toolong," a senior executive at a leading UK bank told Reuters."You've got to be mindful that we saw it as nursing companiesback to financial health and getting a better bank as a result." research chems nolvadex More than half a million applications poured into Immigration and Citizenship Services as of June — and an estimated 400,000 more are eligible. They live in all 50 states — with more than 26,000 applying from New York. cheap malaria tablets doxycycline The Independent newspaper of London reported on its websiteon Friday that the Metropolitan Police Service, also known asScotland Yard, was investigating News International, asMurdoch's London publishing operation was previously known, as a"corporate suspect" over possible "hacking and briberyoffences." buy amlodipine besylate online "It is unrealistic to think that there are not more gay and lesbian men and women who are prominent in sport. The fact that a fear still exists in terms of coming out in the sporting world is testament to how far we still have to go," he insisted.

redpajama_set_name: RedPajamaCommonCrawl


V by Very Curve Hem Nylon Parka. This curve hem parka from V by Very brings cool urban vibes to your autumn winter wardrobe. Padded for warmth with a subtle sheen, it features a zip-off hood to personalise, revealing a ribbed collar beneath.Styling IdeasGet that city-cool look by wearingwith skinny jeans or a leather skirt.


Arlington, VA, December 3, 2018 – The Consumer Technology Association (CTA)TM today announced the results of an independent audit confirming a record-breaking CES Asia 2018 with attendance numbers reaching the highest in show history. Overall attendance at Asia's premier tech event saw a 21 percent increase over 2017, setting a record of 46,748 attendees from 75 countries, regions and territories, including a record number of 1,439 media. Since its inception in 2015, CES Asia attendance has grown 63 percent. CES Asia 2019 will return to Shanghai, June 11-13, 2019.
CES Asia 2018 hosted 529 exhibitors from across the globe, up 14 percent from last year's show. CES Asia 2018 also saw major growth with its show floor spanning 25,706 net square meters, a nearly 25 percent increase compared to CES Asia 2017. The 2019 event is on track for continued growth with new exhibit hall and major brands exhibiting, including 3M, Audio-Technica, Baidu DuerOS, Continental, Desay SV, Digital China, Dow, Fengxiu, Fossil/Misfit, Garmin, Hanergy, Huawei, Libratone, NavInfo, Neusoft, OtterBox, PICO, SF-Express, Skyworth, Sogou, Sonos, Suning, and Wacom.
The CES Asia 2019 call for speakers is now accepting conference proposal submissions through February 5, 2019. Registration for CES Asia 2019 will open in January 2019.
For the latest CES Asia news, information, photos, b-roll and more, visit CESAsia.com.
Final numbers for CES Asia 2018, one of the few shows to be independently audited, are provided by BPA Worldwide. The CES Asia audit provides absolute verification of exhibition records, including direct on-site observation, examination of registration systems and testing of attendee records. This audit complies with the industry standards for audits adopted by both the EEIAC and the International Association of Exhibition and Events (IAEE). CES Asia is also certified by UFI, the Global Association of the Exhibition Industry.
High-definition video b-roll from CES Asia is available for easy download on CESAsia.com.
For questions about exhibiting at CES Asia, contact Brian Moon at bmoon@CTA.tech or +1 703-907-4351.


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Litton Industries — американская промышленная компания, крупный производитель техники оборонного назначения и вооружений. Около половины доходов от продаж продукции и предоставляемых услуг составляет федеральный клиентский сектор обслуживания военных заказов (без учёта иностранных заказчиков американского вооружения и военной техники). Стабильно входила в дюжину крупнейших подрядчиков военно-промышленного комплекса США по объёму заказов. В 2001 году была приобретена в собственность компанией Northrop Grumman за 5,1 млрд долларов.

История

Начала свою историю с 1953 года как небольшой производитель навигационного оборудования, систем связи и электронной борьбы. В 1962 году ею была поглощена компания Ingalls Shipbuilding, затем в 1983 году — компания International Laser Systems, Inc. К 1990-м годам стала основным производителем крупных надводных кораблей для ВМС США. В 1990 году компания стала слишком большой для эффективного управления и была разделена на две группы. Первая, занимающаяся оборонными контрактами сохранила первоначальное название, в то время как вторая, занимающаяся гражданскими проектами, была названа Western Atlas Inc. В настоящее время компания Litton Industries насчитывает более 80 подразделений в разных странах мира, которые разрабатывают и производят оптоэлетронные приборы, радиолокационное оборудование, лазерную технику, компьютеры, комплектующие, расходные материалы, элементную базу и т. д.

Примечания

Ссылки
 Компания Litton Industries, Inc. на сайте www.encyclopedia.com
 Компания Litton Industries, Inc. на сайте Энциклопедии Британники

Производители оптики
Машиностроительные компании США
Оборонно-промышленный комплекс США

redpajama_set_name: RedPajamaWikipedia


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Jüdisches Leben EN » people » Feldmann, David
David Feldmann
David Feldmann was born on September 13th, 1894 in Altenmuhr (Old Muhr) to parents Joseph an Karolina Feldmann. In 1911 he moved to Gunzenhausen, and 1919 he got official residency. He ran his fathers store for manufactured products there on the Marktplatz 9. He married Bertha Klein (born 04.08.1894) on 05.04.1921, in Marktbreit. Bertha was the daughter of Sigmund Klein, al salesman and Hedwig Silbermann.
The family has three kids:
Ruth Fanny, born 18th January 1922 in Gunzenhausen
The twins Lothar Albert and Ernst Leopold, born 04. January 1926.
In 1928 David Feldmann's father, Joseph Feldmann died. Interestingly he was the secretary from the association of former members of the royal Bavarian infantry regiment Prince Ludwig. The descendants sold his collection of Fayencen and Zinn to the city of Gunzenhausen in 1929.
In March of 1932, the Family moved to the house on Gerberstrasse 5 and ran their store there. But in early 1933, David Feldmann was arrested and sent to Dachau.
He was releast on 28.07.1933, however. The family emigrates to New York in on 26.08.1938.
Altmühl-Bote from 13. July 1938. The last shop run by Jews closes.


Goodyear is a New Zealand veteran, establishing operations in 1917 with imported tyres and commencing production in New Zealand 1949. There are numerous Goodyear stores throughout the country and you can locate your nearest Goodyear retailer here. An interesting fact: Goodyear tyres were used on Henry Ford's Model T when it was first produced in 1908!
The Goodyear blimp is a well-recognised feature in the skies – and even has its own Facebook page!
In addition to tyres you can buy Goodyear apparel (even a Goodyear blimp keyring) as well as branded racing merchandise.
Beaurepaires performed well in Canstar Blue's 2015 car tyre retailers customer satisfaction survey, scoring impressive four and five stars across most categories assessed, including five stars for range of brands and tyre quality.
Cost of getting four new tyres!
They were incredibly helpful and obliging on a Saturday morning when my son had had 2 tyre's slashed and he was unable to go to them.


CSW|ST2 has provided a wide variety of engineering and related design services to complete the adaptive re-use of this 1,000 acre former Army Air Force Base. Currently nearing completion, this unique mixed-use community sets the standard for responsible and efficient development. The project carefully accommodates the creation of 473 single family homes, 708 multi-family residences, two public parks, and the adaptive reuse of over 1 million sq.ft. of hangars, administrative and non-residential facilities into assorted commercial uses.
Services provided by CSW|ST2 included land planning and full civil engineering design improvements to complete all roadways, sanitary sewer and storm drainage facilities, all easement and boundary resolutions, and all construction staking. Additional services within the reuse area included construction management, contract documents for bidding, construction, and mapping for recordation. A special feature of the project is the reclamation of nearly 100 acres of wetlands along the site's bay-fronting boundary.


You searched for subject:(High performance). Showing records 1 – 30 of 2015 total matches.
1. Jalili Marandi, Parisa. High-performance state-machine replication.
▼ Replication, a common approach to protecting applications against failures, refers to maintaining several copies of a service on independent machines (replicas). Unlike a stand-alone service, a replicated service remains available to its clients despite the failure of some of its copies. Consistency among replicas is an immediate concern raised by replication. In effect, an important factor for providing the illusion of an uninterrupted service to clients is to preserve consistency among the multiple copies. State-machine replication is a popular replication technique that ensures consistency by ordering client requests and making all the replicas execute them deterministically and sequentially. The overhead of ordering the requests, and the sequentiality of request execution, the two essential requirements in realizing state-machine replication, are also the two major obstacles that prevent the performance of state-machine replication from scaling. In this thesis we concentrate on the performance of state-machine replication and enhance it by overcoming the two aforementioned bottlenecks, the overhead of ordering and the overhead of sequentially executing commands. To realize a truly scalable system, one must iteratively examine and analyze all the layers and components of a system and avoid or eliminate potential performance obstructions and congestion points. In this dissertation, we iterate between optimizing the ordering of requests and the strategies of replicas at request execution, in order to stretch the performance boundaries of state-machine replication. To eliminate the negative implications of the ordering layer on performance, we devise and implement several novel and highly efficient ordering protocols. Our proposals are based on practical observations we make after closely assessing and identifying the shortcomings of existing approaches. Communication is one of the most important components of any distributed system and thus selecting efficient communication patterns is a must in designing scalable systems. We base our protocols on the most suitable communication patterns and extend their design with additional features that altogether realize our protocol's high efficiency. The outcome of this phase is the design and implementation of the Ring Paxos family of protocols. According to our evaluations these protocols are highly scalable and efficient. We then assess the performance ramifications of sequential execution of requests on the replicas of state-machine replication. We use some known techniques such as state-partitioning and speculative execution, and thoroughly examine their advantages when combined with our ordering protocols. We then exploit the features of multicore hardware and propose our final solution as a parallelized form of state-machine replication, built on top of Ring Paxos protocols, that is capable of accomplishing significantly high performance. Given the popularity of state-machine replication in designing fault-tolerant systems, we hope this thesis provides useful and… Advisors/Committee Members: Fernando (Dir.).
Jalili Marandi, Parisa. "High-performance state-machine replication." 2014. Thesis, Università della Svizzera italiana. Accessed April 22, 2019. http://doc.rero.ch/record/213291.
Jalili Marandi, Parisa. "High-performance state-machine replication." 2014. Web. 22 Apr 2019.
Jalili Marandi P. High-performance state-machine replication. [Internet] [Thesis]. Università della Svizzera italiana; 2014. [cited 2019 Apr 22]. Available from: http://doc.rero.ch/record/213291.
2. Gehrke, Lori R. Case studies of two high-poverty high-performing schools.
▼ The existing literature on learning organizations emphasize that leadership and strong organizational culture are central to their successful development. Whereas schools continue to face government control, accountability, and financial restraints, they are also working diligently to engage in ongoing school improvement practices to provide learning opportunities for all students. Existing literature supports a link between culture and leadership and the academic achievement of high-poverty and high-performing schools. However, this theoretical construct required further investigation to explore disciplines for creating an optimum learning organization and, in turn, its impact on student achievement. The purpose of this research was to investigate the disciplines evident within two Illinois schools identified with both high-student poverty and high-performance rates. This qualitative study particularly investigates disciplines contributing to the overall school environment impacting student performance. Moreover, this case study provides an in-depth examination of the disciplines present in high-poverty schools that are demonstrating high-student achievement. Advisors/Committee Members: Hunter, Richard C. (advisor), Hunter, Richard C. (Committee Chair), Witz, Klaus (committee member), Alexander, S. Kern (committee member), Thurston, Paul W. (committee member).
Gehrke, Lori R. "Case studies of two high-poverty high-performing schools." 2011. Thesis, University of Illinois – Urbana-Champaign. Accessed April 22, 2019. http://hdl.handle.net/2142/18457.
Gehrke, Lori R. "Case studies of two high-poverty high-performing schools." 2011. Web. 22 Apr 2019.
Gehrke LR. Case studies of two high-poverty high-performing schools. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2011. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/2142/18457.
3. Khogali, Rashid. Cost minimization of algorithms for scheduling parallel, single-threaded, heterogeneous, speed-scalable processors.
Khogali, Rashid. "Cost minimization of algorithms for scheduling parallel, single-threaded, heterogeneous, speed-scalable processors." 2013. Thesis, Ryerson University. Accessed April 22, 2019. https://digital.library.ryerson.ca/islandora/object/RULA%3A2919.
Khogali, Rashid. "Cost minimization of algorithms for scheduling parallel, single-threaded, heterogeneous, speed-scalable processors." 2013. Web. 22 Apr 2019.
Khogali R. Cost minimization of algorithms for scheduling parallel, single-threaded, heterogeneous, speed-scalable processors. [Internet] [Thesis]. Ryerson University; 2013. [cited 2019 Apr 22]. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A2919.
4. Dufour, Bruno, 1981-. Practical analysis of framework-intensive applications:.
Many modern applications (e.g. web applications) are composed of a relatively small amount of application code that calls a large number of third-party libraries and frameworks. Such framework-intensive systems typically exhibit different characteristics from traditional applications. Current tools and techniques are often inadequate in analyzing applications of such scale and complexity. Approaches based on static analysis suffer problems of insufficient scalability and/or insufficient precision. Purely dynamic analyses, introduce too much execution overhead, especially for production systems, or are too limited in the information gathered. The main contribution of this thesis is a new analysis paradigm, blended analysis, combines elements of static and dynamic analyses in order to enable analyses of framework-intensive applications that achieve good precision at a practical cost. This is accomplished by narrowing the focus of a static analysis to a set of executions of interest identified using a lightweight dynamic analysis. We also present an optimization technique that further reduces the amount of code to be analyzed by removing infeasible basic blocks, and leads to significant increases in scalability and precision of the analysis. We contribute Elude, a publicly available framework for blended analysis of Java programs. We demonstrate the usefuless of blended analysis in practice by applying it to object churn, a common problem in framework-intensive applications caused by the excessive usage of temporary objects. We present a set of new metrics to characterize the usage and complexity of temporaries. We use an instantiation of the blended analysis paradigm, blended escape analysis, to compute these metrics for a set of real framework-intensive applications. Using these results we perform a detailed analysis of temporaries in these applications. We also use our technique to identify a set of problematic scenarios in a commercial application.
Advisors/Committee Members: Dufour, Bruno, 1981- (author), Ryder, Barbara (chair), Borgida, Alex (internal member), Ganapathy, Vinod (internal member), Podgurski, Andy (outside member).
Dufour, Bruno, 1981-. "Practical analysis of framework-intensive applications:." 2010. Doctoral Dissertation, Rutgers University. Accessed April 22, 2019. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000052105.
Dufour, Bruno, 1981-. "Practical analysis of framework-intensive applications:." 2010. Web. 22 Apr 2019.
Dufour, Bruno 1. Practical analysis of framework-intensive applications:. [Internet] [Doctoral dissertation]. Rutgers University; 2010. [cited 2019 Apr 22]. Available from: http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000052105.
5. Bowman, Clark Michael Riordan. Data-Calibrated Modeling of Biological Soft Matter with Dissipative Particle Dynamics and High-Performance Bayesian Uncertainty Quantification.
▼ Fluids play a key role in the mechanics of cells and the soft-matter structures composing them; from the movement of molecules such as amino acids via diffusion to the viscous forces propelling flagellating organisms, accounting for the role of the fluid environment is critical to understanding the mechanisms at play. One of the major challenges in mathematical modeling of such systems is developing an accurate, yet computationally feasible representation of the fluid. Continuum approaches such as Navier-Stokes neglect the thermal fluctuations and boundary effects than can dominate flow behavior at the nanoscale, while explicit models of the fluid via, e.g., molecular dynamics become computationally infeasible for systems on the order of biological cells which may have millions or billions of molecules. In this thesis, we use dissipative particle dynamics, a particle method which uses coarse-grained particles interacting with artificial forces chosen to generate accurate fluid behavior, to model a number of biofluidic systems of experimental interest, including the diffusion of DNA in constrained environments, the mechanics of poration in phospholipid membranes, and the mechanical force profile of polymerizing actin networks in the cytoskeleton. The simulation results are used to examine at the nanoscale the dynamics underlying macroscopic behaviors observed in experiment, answering a number of questions about the forces, energies, motions, and mechanisms of biological soft matter with measurements from the explicitly modeled fluid environment. We also introduce a framework for high-performance Bayesian uncertainty quantification and demonstrate an application to inferring structural properties of lipids in a bilayer membrane, illustrating the feasibility of data-driven model calibration for our complex dissipative particle simulations using parallel computing. Together, these methods allow for a uniquely fine-scale look at the mechanics underpinning a number of biologically relevant phenomena. Advisors/Committee Members: Matzavinos, Anastasios (Advisor), Stein, Derek (Reader), Chaplain, Mark (Reader).
Bowman, Clark Michael Riordan. "Data-Calibrated Modeling of Biological Soft Matter with Dissipative Particle Dynamics and High-Performance Bayesian Uncertainty Quantification." 2018. Thesis, Brown University. Accessed April 22, 2019. https://repository.library.brown.edu/studio/item/bdr:792771/.
Bowman, Clark Michael Riordan. "Data-Calibrated Modeling of Biological Soft Matter with Dissipative Particle Dynamics and High-Performance Bayesian Uncertainty Quantification." 2018. Web. 22 Apr 2019.
Bowman CMR. Data-Calibrated Modeling of Biological Soft Matter with Dissipative Particle Dynamics and High-Performance Bayesian Uncertainty Quantification. [Internet] [Thesis]. Brown University; 2018. [cited 2019 Apr 22]. Available from: https://repository.library.brown.edu/studio/item/bdr:792771/.
6. Rietmann, Max. Local time stepping on high performance computing architectures: mitigating CFL bottlenecks for large-scale wave propagation.
▼ Modeling problems that require the simulation of hyperbolic PDEs (wave equations) on large heterogeneous domains have potentially many bottlenecks. We attack this problem through two techniques: the massively parallel capabilities of graphics processors (GPUs) and local time stepping (LTS) to mitigate any CFL bottlenecks on a multiscale mesh. Many modern supercomputing centers are installing GPUs due to their high performance, and extending existing seismic wave-propagation software to use GPUs is vitally important to give application scientists the highest possible performance. In addition to this architectural optimization, LTS schemes avoid performance losses in meshes with localized areas of refinement. Coupled with the GPU performance optimizations, the derivation and implementation of an Newmark LTS scheme enables next-generation performance for real-world applications. Included in this implementation is work addressing the load-balancing problem inherent to multi-level LTS schemes, enabling scalability to hundreds and thousands of CPUs and GPUs. These GPU, LTS, and scaling optimizations accelerate the performance of existing applications by a factor of 30 or more, and enable future modeling scenarios previously made unfeasible by the cost of standard explicit time-stepping schemes. Advisors/Committee Members: Olaf (Dir.).
Rietmann, Max. "Local time stepping on high performance computing architectures: mitigating CFL bottlenecks for large-scale wave propagation." 2015. Thesis, Università della Svizzera italiana. Accessed April 22, 2019. http://doc.rero.ch/record/255915.
Rietmann, Max. "Local time stepping on high performance computing architectures: mitigating CFL bottlenecks for large-scale wave propagation." 2015. Web. 22 Apr 2019.
Rietmann M. Local time stepping on high performance computing architectures: mitigating CFL bottlenecks for large-scale wave propagation. [Internet] [Thesis]. Università della Svizzera italiana; 2015. [cited 2019 Apr 22]. Available from: http://doc.rero.ch/record/255915.
7. Sims, John, L. Jr. Improving math instruction in schools that serve the poor.
▼ Public alarm concerning how well U.S. schools are performing in mathematics compared to other developed nations is increasing. Reports of inadequate teaching, poor curriculum design, and low performance on standardized test have been fueled by the media. These issues in American mathematics classrooms are far compounded in schools that serve the poorest in America. When comparing mathematical proficiency rates of U.S. schools with other countries, schools with less than 25% free and reduced lunch score competitively with counterparts in other countries. In contrast, schools with rates of free and reduced lunch higher than 50% score dismally in comparison. Conditions such as poorly trained teachers, lack of support, insufficient instructional programs, focus on low level skills, low expectations, overwhelming workloads, poor work conditions all contribute to the inferior level of instruction received by students in these schools. There are, however, schools that serve students of poverty that are beating the odds and performing on par and in some cases better than schools that serve more affluent students. To determine what can be reproduced elsewhere, this thesis take a look what is taking place in these schools: a demanding curriculum, implementation of problem solving, deep understanding and communication of mathematics, continual reworking of curriculum, using varied instructional practices, building relationships, and teacher leadership. For instructional practices to improve, teachers must step up and become leaders in the classroom to impact the environment and school culture. Six principles are discussed that are critical to making the changes necessary to impact student achievement in schools that serve the poor. To assist in the battle to improve instruction and student learning in schools that serve the poor, colleges and universities can play a critical role. This thesis describes the preliminary outcomes of two large-scale LSU projects at high need, high poverty schools in the Greater Baton Rouge area: the Pilot Professional Development Project and the Baker Project. It is hoped that the lessons learned will help others to start similar programs at one of the many schools that serve the poor that in dire need for help from higher education mathematics departments.
Sims, John, L Jr. "Improving math instruction in schools that serve the poor." 2010. Masters Thesis, Louisiana State University. Accessed April 22, 2019. etd-01272011-151106 ; https://digitalcommons.lsu.edu/gradschool_theses/173.
Sims, John, L Jr. "Improving math instruction in schools that serve the poor." 2010. Web. 22 Apr 2019.
Sims, John LJ. Improving math instruction in schools that serve the poor. [Internet] [Masters thesis]. Louisiana State University; 2010. [cited 2019 Apr 22]. Available from: etd-01272011-151106 ; https://digitalcommons.lsu.edu/gradschool_theses/173.
8. Williamson, Leah Nicole. Novel methods for the quantitation of central nervous system agents.
▼ Humans can be exposed to central nervous system agents environmentally and/or therapeutically. Chronic exposure to these agents can cause damage to the central nervous system. In order to study the neurological effects of these agents, sensitive and selective analytical methods must be developed and validated in biological matrices, such as brain tissue, plasma, and whole blood. Chlorpyrifos (CPF) is an organophosphate pesticide that inhibits acetylcholinesterase, which is an enzyme that is necessary for normal function of the nervous system. CPF is metabolized by cytochrome P450 into chlorpyrifos-oxon (CPF-O) and TCP. CPF-O is about 3,000 times more potent than CPF in its inhibition of acetylcholinesterase activity, while TCP is non-toxic and is eliminated by the kidneys. Therapeutically, chronic exposure to antipsychotic drugs can result in abnormalities in motor function. Additionally, it is important to determine the extent to which a correlation exists between plasma and brain levels of these agents and cognitive function. Chapter 1 is the introduction and literature review that describes the layout of the dissertation and reviews the literature for analytical methods using liquid chromatography with time-of-flight mass spectrometry (TOF-MS) for quantitation. Chapter 2 reviews the literature for analytical methods using gas chromatography and TOF-MS for quantitation. Chapters 3 and 4 present analytical methods for the quantitation of CPF and its metabolites in rat brain tissue and blood using liquid chromatography and tandem mass spectrometry (LC-MS/MS). A TOF-MS analytical method for the quantitation of five antipsychotic drugs in rat plasma is presented in chapter 5. Advisors/Committee Members: Michael Bartlett.
Williamson, Leah Nicole. "Novel methods for the quantitation of central nervous system agents." 2007. Doctoral Dissertation, University of Georgia. Accessed April 22, 2019. http://purl.galileo.usg.edu/uga_etd/williamson_leah_n_200708_phd.
Williamson, Leah Nicole. "Novel methods for the quantitation of central nervous system agents." 2007. Web. 22 Apr 2019.
Williamson LN. Novel methods for the quantitation of central nervous system agents. [Internet] [Doctoral dissertation]. University of Georgia; 2007. [cited 2019 Apr 22]. Available from: http://purl.galileo.usg.edu/uga_etd/williamson_leah_n_200708_phd.
9. Algar, Lynne. A critical examination of talent development systems in high performance sport.
Advisors/Committee Members: MacDonncha, Ciaran, MacNamara, Áine.
Algar, Lynne. "A critical examination of talent development systems in high performance sport." 2015. Thesis, University of Limerick. Accessed April 22, 2019. http://hdl.handle.net/10344/4780.
Algar, Lynne. "A critical examination of talent development systems in high performance sport." 2015. Web. 22 Apr 2019.
Algar L. A critical examination of talent development systems in high performance sport. [Internet] [Thesis]. University of Limerick; 2015. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/10344/4780.
10. Desalegne, Admasu S. Shear Behaviour of Concrete Slabs and Beams Reinforced with High-Performance ASTM A1035 Steel.
▼ High-performance steel bars manufactured to conform to ASTM A1035-11 have different metallurgy and microstructure than conventional reinforcing steel. These changes result in an effective yield strength significantly higher than conventional ASTM A615 steel while also being less susceptible to corrosion. Thus there is increasing interest in the use of ASTM A1035 steel to reduce life-cycle costs for new concrete structures. However, the lack of a well defined yield point for this material requires careful assessment of structural design models to ensure that they accurately account for influences from higher reinforcement strains. This research focuses on the behaviour of shear-critical concrete members containing ASTM A1035 steel reinforcement. Laboratory tests were completed for six slab strips and ten beams with overall heights ranging from 300 mm to 1000 mm and shear span to depth ratios of 3.0 – 3.6. In the current study the term "SLABS" refer to concrete members longitudinally reinforced with ASTM A1035 steel without stirrups and "BEAMS" refer to members with stirrups containing combinations of ASTM A1035 or Grade 420 steel. The influence on shear and deflection behaviour from the reinforcement configurations and the nonlinear stress-strain response of the ASTM A1035 steel were of primary interest. General analytical shear models were developed for members containing ASTM A1035 steel. Simplified design shear models were also developed where the longitudinal ASTM A1035 reinforcement is proportioned on the basis of 690 MPa yield strength. All models were validated using the new experimental test results and data from the literature. The proposed shear models were also compared with existing analytical and numerical models. Improved capacity predictions were obtained from models that directly account for the influence of reinforcement strains and member depth. It was observed that the service load deflections of beams were underestimated by existing code deflection models such as the ACI ITG–6R-10 direct deflection model. Based on parametric studies, general deflection model and simplified deflection equations were developed for the beams containing ASTM A1035 steel reinforcement. The equations were validated against test results and were shown to be useful for deflection calculations in the design industry.
Desalegne, Admasu S. "Shear Behaviour of Concrete Slabs and Beams Reinforced with High-Performance ASTM A1035 Steel." 2013. Doctoral Dissertation, University of Alberta. Accessed April 22, 2019. https://era.library.ualberta.ca/files/m900nv06b.
Desalegne, Admasu S. "Shear Behaviour of Concrete Slabs and Beams Reinforced with High-Performance ASTM A1035 Steel." 2013. Web. 22 Apr 2019.
Desalegne AS. Shear Behaviour of Concrete Slabs and Beams Reinforced with High-Performance ASTM A1035 Steel. [Internet] [Doctoral dissertation]. University of Alberta; 2013. [cited 2019 Apr 22]. Available from: https://era.library.ualberta.ca/files/m900nv06b.
11. Kataria, Suresh. Assessment of grouts for constructability and durability of post-tensioned bridges.
▼ Post-tensioned (PT) bridge technology was first introduced in France in the 1930?s as described in the post-tensioned concrete bridges: Anglo-French liaison report by Highway Agency and is widely used in Europe and the US. PT bridge technology is advantageous over other bridge-type structures due to its larger span-to-depth ratio and reduced construction costs and time. This technology however faces several challenges due to potential corrosion of the prestressing steel. PT bridges constructed in the US during the 1970?s used cementitious grouts to fill the empty spaces in the PT ducts in order to protect the strands from corrosion. This grout in the ducts was intended to protect the strands from being attacked by aggressive agents and to prevent corrosion. A mixture of ASTM Type I cement and water was used as the grouting material for construction of PT bridges. In Texas, four major PT structures have been in place for more than 10 years. Recent investigations of the PT bridges in Texas did not identify any strand failures. However, the visual inspections identified voids in many of the ducts, especially at the ends of the bridge spans. These voids are believed to have been formed as a result of grout bleeding, poor grouting materials, and poor grouting techniques. One of the main performance requirements sought from PT grouts is their ability to fill existing voids in the existing ducts. Currently, many prepackaged grouts are available for PT application that are reported to not bleed and provide better flowability as compared to the older ASTM Type I cement grout. However, the current standard specifications for approving grout materials have limited requirements for evaluating the ?fillability? of these pre-packaged PT grouts. This research is being performed to provide modifications to the existing PT specifications such that PT repair grouts can be objectively assessed for fillability and long-term performance. Advisors/Committee Members: Trejo, David (advisor), Reinschmidt, Kenneth F. (committee member), Teodoriu, Catalin (committee member).
Kataria, Suresh. "Assessment of grouts for constructability and durability of post-tensioned bridges." 2010. Thesis, Texas A&M University. Accessed April 22, 2019. http://hdl.handle.net/1969.1/ETD-TAMU-2008-08-50.
Kataria, Suresh. "Assessment of grouts for constructability and durability of post-tensioned bridges." 2010. Web. 22 Apr 2019.
Kataria S. Assessment of grouts for constructability and durability of post-tensioned bridges. [Internet] [Thesis]. Texas A&M University; 2010. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2008-08-50.
12. Bawjee, Janita. An evaluation of UPLC technology for the simultaneous analysis of actives in a multi-active drug.
▼ The evaluation of the potential to use Ultra Performance Liquid Chromatography (UPLC) for the simultaneous quantification of all the actives in a multi-active tablet is described in this work. Part of the evaluation was to ensure that the necessary regulatory requirements were adhered to by ascertaining that an analytical method is suitable for a specific purpose through analytical method validation for the specific multi-active tablet. The UPLC method was also tested for the analysis of similar products, namely tablet formulations that contain similar active ingredients in the same proportions but with an additional active ingredient. A method for the simultaneous determination of paracetamol, caffeine and codeine phosphate was developed using UPLC technology. The UPLC developed method was more efficient than the existing in-house HPLC method. The UPLC method was then validated in accordance to ICH and USP guidelines. The application of this UPLC method for the analysis of similar products containing paracetamol, caffeine, codeine phosphate and one extra active ingredient was very challenging. The low concentration of the additional component, differences in sample matrix and differences in formulations added to the challenges. The direct application for the analysis of products Y and Z was not successful; however the method could be used as a platform for further research. A cost comparison between the UPLC and HPLC methods showed the UPLC method to be more cost effective. Thus, while maintenance costs are higher for the UPLC instrument, column costs are comparable to HPLC columns, but solvent and waste disposal charges decrease considerably due to lower solvent use. The reduction in instrument time dramatically improves the cost effectiveness of UPLC over HPLC due to a concurrent reduction in analyst time requirement. The results of this study show that the analytical costs associated with the analysis of multi-active drugs using HPLC procedures can be reduced substantially by the CONFIDENTIAL INTELLECTUAL PROPERTY OF ASPEN PHARMACARE implementation of UPLC technology. The hypothesis that the enhanced chromatographic power of UPLC can be leveraged to provide faster analysis times hence increased product throughput rates, and lower operating costs for the analysis of multi-active drugs was accepted. These advantages were achieved whilst meeting all regulatory requirements for analytical methods as required by regulatory bodies.
Bawjee, Janita. "An evaluation of UPLC technology for the simultaneous analysis of actives in a multi-active drug." 2011. Thesis, Nelson Mandela Metropolitan University. Accessed April 22, 2019. http://hdl.handle.net/10948/d1008407.
Bawjee, Janita. "An evaluation of UPLC technology for the simultaneous analysis of actives in a multi-active drug." 2011. Web. 22 Apr 2019.
Bawjee J. An evaluation of UPLC technology for the simultaneous analysis of actives in a multi-active drug. [Internet] [Thesis]. Nelson Mandela Metropolitan University; 2011. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/10948/d1008407.
13. Williams, Karen L. Effect of oligomer chain length and substituent configuration on the enantioselectivity of a maltooligosaccharide chiral stationary phrase for HPLC.
The effect of naphthylethylcarbamate (NEC) substituent configuration on the enantioselectivity of maltooligosaccharide-based chiral stationary phases (CSPs) was investigated by preparing bonded phases derivatized with (R)-, (S)-, and racemic l-(l-naphthyl)ethyl isocyanate. Various 3,5-dinitrobenzoyl derivatized amines and amino acid esters, as well as 3,S-dinitrophenylcarbamoylated alcohols, were utilized as analytes. In most instances, retention was found to correlate with the surface concentration of the bonded ligands. The best enantioselectivity typically occurred on the S-NEC CSP. Elution order of the enantiomers provided an indication of the importance of carbamate substituent configuration in chiral recognition. The chiral carbohydrates were also found to contribute to the chiral selectivity of the CSP. The effect of mobile phase and derivatizing agent on the chromatographic behavior of the NEC CSPs was also evaluated. An isocyanate derived from (S)-6-methoxy-α-methyl-2-naphthaleneacetic acid, via an azide intermediate, was evaluated as a derivatizing agent and found to produce a CSP with comparable selectivity and superior resolution relative to the NEC CSPs. In order to gain insight into the nature of the bonded maltooligosaccharide mixture, derivatized bonded phases were prepared using maltotriose, maltopentaose, and maltoheptaose as the carbohydrate ligand. Surface concentrations of the bonded glucose oligomers were found to decrease as the carbon chain length of the oligomer increased. In general, retention, selectivity, and resolution diminished as the oligomer chain lengthened. Comparison of the selectivities of the derivatized glucose oligomer CSPs to those of a derivatized maltooligosaccharide CSP provided a measure of the relative effectiveness of the maltooligosaccharide mixture as a chiral selector.
Williams, Karen L. "Effect of oligomer chain length and substituent configuration on the enantioselectivity of a maltooligosaccharide chiral stationary phrase for HPLC." 2009. Doctoral Dissertation, University of Hawaii – Manoa. Accessed April 22, 2019. http://hdl.handle.net/10125/9522.
Williams, Karen L. "Effect of oligomer chain length and substituent configuration on the enantioselectivity of a maltooligosaccharide chiral stationary phrase for HPLC." 2009. Web. 22 Apr 2019.
Williams KL. Effect of oligomer chain length and substituent configuration on the enantioselectivity of a maltooligosaccharide chiral stationary phrase for HPLC. [Internet] [Doctoral dissertation]. University of Hawaii – Manoa; 2009. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/10125/9522.
14. Bueling, Alexandra Lee. Insights into the role of HydF-catalyzed GTP activity in hydrogenase maturation.
▼ The [FeFe]-hydrogenase contains an unusual active-site cluster, the H-cluster, composed of a [4Fe-4S] cluster bridged to a 2Fe subunit coordinated by CO, CN-, and a nonprotein bridging dithiolate. Three accessory proteins, HydE, HydF, and HydG are required for maturation of the H-cluster. It has been proposed that the GTP-hydrolyzing protein HydF acts as a scaffold for assembly of the [2Fe] subcluster, which is then transferred to hydrogenase to produce the active enzyme[McGlynn, S.M.; Shepard, E.M.; Winslow, M.A.; Naumov, A.V.; Duschene, K.S.; Posewitz, M.C.; Broderick, W.E.; Broderick, J.B.; Peters, J.W. FEBS Lett. 2008, 582, 2183.]. The precise roles of HydE, HydF, and HydG in this process, however, remain unclear. The overall goal of this work is to study the role of HydF in hydrogenase maturation. In vivo studies have identified specific amino acid residues of HydF necessary for production of active hydrogenase [King, P.W.; Posewitz, M.C.; Ghirardi, M.L.; Seibert, M. J Bacteriol. 2006, 188, 2163.]. The objectives of this study were to: 1) investigate the involvement of each of these amino acid residues on the GTP hydrolyzing ability of HydF 2) examine the effects of structural and accessory hydrogenase proteins on rate of GTP hydrolysis 3) examine the importance of [Fe-S] cluster in HydF GTPase activity. GTPase assays were analyzed by high performance liquid chromatography (HPLC). The results indicate mutations to conserved glycine residues in the GTP binding loop, and a potential iron ligand for the [Fe-S] cluster are deleterious to GTPase activity. Another mutation in the GTP binding loop involved in Mg ²+ coordination appears to have little effect on the rate of GTP hydrolysis. The two accessory proteins HydE and HydG increased GTPase activity, while the hydrogenase structural protein (HydA) appears to have little effect, supporting the suggestion that HydF acts as a scaffold. The presence or absence of an iron-sulfur cluster does not significantly affect GTPase activity. Together, these results suggest GTP hydrolysis does not play a role in transfer of activating elements to hydrogenase, but does play a role in hydrogenase maturation. Advisors/Committee Members: Chairperson, Graduate Committee: Joan B. Broderick. (advisor).
Subjects/Keywords: Hydrogenase.; High performance liquid chromotography.
Bueling, Alexandra Lee. "Insights into the role of HydF-catalyzed GTP activity in hydrogenase maturation." 2009. Thesis, Montana State University. Accessed April 22, 2019. https://scholarworks.montana.edu/xmlui/handle/1/1006.
Bueling, Alexandra Lee. "Insights into the role of HydF-catalyzed GTP activity in hydrogenase maturation." 2009. Web. 22 Apr 2019.
Bueling AL. Insights into the role of HydF-catalyzed GTP activity in hydrogenase maturation. [Internet] [Thesis]. Montana State University; 2009. [cited 2019 Apr 22]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/1006.
15. Burcham, Megan Noel. Multiscale structure-property relationships of ultra-high performance concrete.
▼ The structure-property relationships of Ultra-High Performance Concrete (UHPC) were quantified using imaging techniques to characterize the multiscale hierarchical heterogeneities and the mechanical properties. Through image analysis the average size, percent area, nearest neighbor distance, and relative number density of each inclusion type was determined and then used to create Representative Volume Element (RVE) cubes for use in Finite Element (FE) analysis. Three different size scale RVEs at the mesoscale were found to best represent the material: the largest length scale (35 mm side length) included steel fibers, the middle length scale (0.54 mm side length) included large voids and silica sand grains, and the smallest length scale (0.04 mm side length) included small voids and unhydrated cement grains. By using three length scales of mesoscale FE modeling, the bridge of information to the macroscale cementitious material model is more physically based. Advisors/Committee Members: Mark F. Horstemeyer (chair), Youssef Hammi (committee member), Tonya W. Stone (committee member).
Burcham, Megan Noel. "Multiscale structure-property relationships of ultra-high performance concrete." 2016. Masters Thesis, Mississippi State University. Accessed April 22, 2019. http://sun.library.msstate.edu/ETD-db/theses/available/etd-06232016-161231/ ;.
Burcham, Megan Noel. "Multiscale structure-property relationships of ultra-high performance concrete." 2016. Web. 22 Apr 2019.
Burcham MN. Multiscale structure-property relationships of ultra-high performance concrete. [Internet] [Masters thesis]. Mississippi State University; 2016. [cited 2019 Apr 22]. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-06232016-161231/ ;.
16. Thomas, Jennifer A. Considering intervention efficacy: the effect of a pre-shot routine on competitive youth golf performance.
▼ A pre-shot routine enables athletes to focus on well rehearsed cues (Schmidt & Pepper, 1998). Pre-shot routines are commonly discussed in golf literature as well as in consultation. Research on routines is scattered; a consistent line of inquiry has not studied all three components of a pre-shot routine (e.g, cognitive, behavioral, and relaxation). Studies have begun to suggest that elite players create their own routines (Cohn, Rotella, & Lloyd, 1990); and thus routines may be particularly beneficial for youth sport performers. Lastly, the literature is still missing studies that employ sound methodological designs, comprehensive interventions teaching adequate mental skills that form a pre-shot routine and social validation of the protocol and results with youth participants. The purpose of this study was to examine the potential efficacy of a pre-shot routine on improving competitive youth golf putting and approach shot performance. The research question was will learning the psychological components (e.g. cognitive cues, behavioral focusing strategies, and relaxation) of a pre-shot routine improve approach shot and putting performance of competitive youth golfers? There were two aims that addressed this research question. The first aim was to determine the impact of learning the mental skills components of a pre-shot routine on the total number of approach shots and putts in tournaments during the competitive season. The hypothesis was that learning a pre-shot routine would result in participants becoming more consistent and/or improved sport performance (e.g, decreasing total number of approach shots and putts per round). The second aim was to examine the potential impact of learning the pre-shot routine on competitive performance from the participants' perspectives and involved them in evaluating the intervention and its impact on their competitive performance. Three youth high school golfers participated in a 10 week program to learn 3 mental skills (i.e, cue words, deep breathing, & behavioral focusing strategy) that would form a pre-shot routine. Participants' competition and practice scorecards were collected, and the total number of strokes per round were graphed and examined for performance improvements. Also, participants completed self-report surveys after each tournament round that asked them to indicate their perceived ability to focus on each hole and whether they adhered to their pre-shot routines. Lastly, participants completed interviews after learning each skill and at the end of the program to evaluate the overall intervention protocol. Performance improvements were observed for 2 participants putting and approach shot performance. Participants found the intervention to be helpful and agreed that their performances (i.e, ball striking, overall performance, iron, wood, & sand shots) improved. Practical implications for sport psychology consultants and future directions were forwarded.; Improving, Intervention, Performance, Psychology, Sports, Youth Advisors/Committee Members: Renee Appaneal (advisor).
Subjects/Keywords: Golf.; High school athletes.; Performance.
Thomas, Jennifer A. "Considering intervention efficacy: the effect of a pre-shot routine on competitive youth golf performance." 2010. Doctoral Dissertation, University of North Carolina – Greensboro. Accessed April 22, 2019. http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=4826.
Thomas, Jennifer A. "Considering intervention efficacy: the effect of a pre-shot routine on competitive youth golf performance." 2010. Web. 22 Apr 2019.
Thomas JA. Considering intervention efficacy: the effect of a pre-shot routine on competitive youth golf performance. [Internet] [Doctoral dissertation]. University of North Carolina – Greensboro; 2010. [cited 2019 Apr 22]. Available from: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=4826.
17. Xie, Chao, Ph. D. High-performance transactional storage.
▼ Developers face a fundamental tension between performance and ease of programming when building complex applications. On the one hand, by freeing developers from having to worry about concurrency and failures, ACID transactions can greatly simplify the task of building applications. These benefits, however, have a cost: in a distributed setting, ACID transactions can limit performance and make systems hard to scale in the presence of contention. On the other hand, the BASE approach can achieve higher performance by providing weakened semantics. Embracing the BASE paradigm, however, exacts its own heavy price: once one renounces consistency guarantees, it is up to developers to explicitly code in their applications the logic necessary to en- sure consistency in the presence of concurrency and faults, making this task complex and error-prone. This dissertation aims to resolve this tension by building database systems that provide both the ease of programming of the ACID approach and the performance that the BASE approach can provide. Our approach depends on the observation that different transactions affect overall performance of applications in different ways. Traditional ACID databases ignore this diversity: they provide a single implementation of the same uniform abstraction across all transactions. This dissertation explores two different ways to leverage the previews key observation to combine performance and ease of programming, and presents two systems, Salt and Callas, inspired by them. Advisors/Committee Members: Alvisi, Lorenzo (advisor), Witchel, Emmett (committee member), Pingali, Keshav (committee member), Aguilera, Marcos (committee member).
Xie, Chao, Ph D. "High-performance transactional storage." 2016. Thesis, University of Texas – Austin. Accessed April 22, 2019. http://hdl.handle.net/2152/42014.
Xie, Chao, Ph D. "High-performance transactional storage." 2016. Web. 22 Apr 2019.
Xie, Chao PD. High-performance transactional storage. [Internet] [Thesis]. University of Texas – Austin; 2016. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/2152/42014.
18. Clay, Matthew Paul. Strained turbulence and low-diffusivity turbulent mixing using high performance computing.
▼ In this thesis, turbulent flows are studied using the method of direct numerical simulation (DNS), whereby exact governing equations are computed without modeling. Beginning with isotropic turbulence and turbulent mixing under axisymmetric contraction, comparisons with experiments are made by directly modeling strain rates from wind tunnel facilities in the DNS. The simulations reproduce key findings from the experiments for the evolution of the one-dimensional component velocity spectra, which are strongly influenced by spectral transfer and pressure-strain mechanisms following the contraction. For simulations of low-diffusivity (i.e., high Schmidt number) turbulent mixing in isotropic turbulence, the increased resolution requirements of the Batchelor scales are addressed by adopting a dual-grid dual-scheme numerical approach. The one-way coupling of the velocity and passive scalar fields, along with their disparate resolution requirements at high Schmidt number, are exploited in the design of the parallel code by computing each field separately in disjoint message passing communicators. Good scalability of the code up to O(105) cores on machines at multiple national supercomputer centers is maintained by overlapping communication and computation through extensive use of shared-memory programming, both in homogeneous and heterogeneous (i.e., GPU-accelerated) computing environments. Simulations of passive scalars maintained under a uniform mean gradient in forced isotropic turbulence are conducted. The highest grid resolution employed is 81923 (0.5 trillion) for a scalar of Schmidt number 512, which is comparable to salinity mixing in the ocean. The results give strong support to the emergence of Batchelor scaling in the scalar spectrum and an approach toward local isotropy with increasing Schmidt number. Advisors/Committee Members: Yeung, P. K. (advisor), Aidun, Cyrus K. (committee member), Ranjan, Devesh (committee member), Smith, Marilyn J. (committee member), Chow, Edmond (committee member).
Clay, Matthew Paul. "Strained turbulence and low-diffusivity turbulent mixing using high performance computing." 2017. Doctoral Dissertation, Georgia Tech. Accessed April 22, 2019. http://hdl.handle.net/1853/60184.
Clay, Matthew Paul. "Strained turbulence and low-diffusivity turbulent mixing using high performance computing." 2017. Web. 22 Apr 2019.
Clay MP. Strained turbulence and low-diffusivity turbulent mixing using high performance computing. [Internet] [Doctoral dissertation]. Georgia Tech; 2017. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/1853/60184.
19. Leon Borja, Edgar. Improving the performance of parallel scientific applications using cache injection.
▼ Cache injection is a viable technique to improve the performance of data-intensive parallel applications. This dissertation characterizes cache injection of incoming network data in terms of parallel application performance. My results show that the benefit of this technique is dependent on: the ratio of processor speed to memory speed, the cache injection policy, and the application's communication characteristics. Cache injection addresses the memory wall for I/O by writing data into a processor's cache directly from the I/O bus. This technique, unlike data prefetching, reduces the number of reads served by the memory unit. This reduction is significant for data-intensive applications whose performance is dominated by compulsory cache misses and cannot be alleviated by traditional caching systems. Unlike previous work on cache injection which focused on reducing host network stack overhead incurred by memory copies, I show that applications can directly benefit from this technique based on their temporal and spatial locality in accessing incoming network data. I also show that the performance of cache injection is directly proportional to the ratio of processor speed to memory speed. In other words, systems with a memory wall can provide significantly better performance with cache injection and an appropriate injection policy. This result implies that multi-core and many-core architectures would benefit from this technique. Finally, my results show that the application's communication characteristics are key to cache injection performance. For example, cache injection can improve the performance of certain collective communication operations by up to 20% as a function of message size. Advisors/Committee Members: Maccabe, Arthur, Riesen, Rolf, Bridges, Patrick, da Silva, Dilma, Teller, Patricia.
Leon Borja, Edgar. "Improving the performance of parallel scientific applications using cache injection." 2009. Doctoral Dissertation, University of New Mexico. Accessed April 22, 2019. http://hdl.handle.net/1928/9348.
Leon Borja, Edgar. "Improving the performance of parallel scientific applications using cache injection." 2009. Web. 22 Apr 2019.
Leon Borja E. Improving the performance of parallel scientific applications using cache injection. [Internet] [Doctoral dissertation]. University of New Mexico; 2009. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/1928/9348.
20. Linford, John Christian. Accelerating Atmospheric Modeling Through Emerging Multi-core Technologies.
▼ The new generations of multi-core chipset architectures achieve unprecedented levels of computational power while respecting physical and economical constraints. The cost of this power is bewildering program complexity. Atmospheric modeling is a grand-challenge problem that could make good use of these architectures if they were more accessible to the average programmer. To that end, software tools and programming methodologies that greatly simplify the acceleration of atmospheric modeling and simulation with emerging multi-core technologies are developed. A general model is developed to simulate atmospheric chemical transport and atmospheric chemical kinetics. The Cell Broadband Engine Architecture (CBEA), General Purpose Graphics Processing Units (GPGPUs), and homogeneous multi-core processors (e.g. Intel Quad-core Xeon) are introduced. These architectures are used in case studies of transport modeling and kinetics modeling and demonstrate per-kernel speedups as high as 40x. A general analysis and code generation tool for chemical kinetics called "KPPA" is developed. KPPA generates highly tuned C, Fortran, or Matlab code that uses every layer of heterogeneous parallelism in the CBEA, GPGPU, and homogeneous multi-core architectures. A scalable method for simulating chemical transport is also developed. The Weather Research and Forecasting Model with Chemistry (WRF-Chem) is accelerated with these methods with good results: real forecasts of air quality are generated for the Eastern United States 65% faster than the state-of-the-art models. Advisors/Committee Members: Sandu, Adrian (committeechair), Ribbens, Calvin J. (committee member), Marr, Linsey C. (committee member), Plassmann, Paul E. (committee member), Nikolopoulos, Dimitrios S. (committee member).
Linford, John Christian. "Accelerating Atmospheric Modeling Through Emerging Multi-core Technologies." 2010. Doctoral Dissertation, Virginia Tech. Accessed April 22, 2019. http://hdl.handle.net/10919/27599.
Linford, John Christian. "Accelerating Atmospheric Modeling Through Emerging Multi-core Technologies." 2010. Web. 22 Apr 2019.
Linford JC. Accelerating Atmospheric Modeling Through Emerging Multi-core Technologies. [Internet] [Doctoral dissertation]. Virginia Tech; 2010. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/10919/27599.
21. Steven Monteiro, Steena Dominica. Statistical Techniques to Model and Optimize Performance of Scientific, Numerically Intensive Workloads.
▼ Projecting performance of applications and hardware is important to several market segments—hardware designers, software developers, supercomputing centers, and end users. Hardware designers estimate performance of current applications on future systems when designing new hardware. Software developers make performance estimates to evaluate performance of their code on different architectures and input datasets. Supercomputing centers try to optimize the process of matching computing resources to computing needs. End users requesting time on supercomputers must provide estimates of their application's run time, and incorrect estimates can lead to wasted supercomputing resources and time. However, application performance is challenging to predict because it is affected by several factors in application code, specifications of system hardware, choice of compilers, compiler flags, and libraries. This dissertation uses statistical techniques to model and optimize performance of scientific applications across different computer processors. The first study in this research offers statistical models that predict performance of an application across different input datasets prior to application execution. These models guide end users to select parameters that produce optimal application performance during execution. The second study offers a suite of statistical models that predict performance of a new application on a new processor. Both studies present statistical techniques that can be generalized to analyze, optimize, and predict performance of diverse computation- and data-intensive applications on different hardware. Advisors/Committee Members: Amanda Lee Hughes.
Steven Monteiro, Steena Dominica. "Statistical Techniques to Model and Optimize Performance of Scientific, Numerically Intensive Workloads." 2016. Doctoral Dissertation, Utah State University. Accessed April 22, 2019. https://digitalcommons.usu.edu/etd/5228.
Steven Monteiro, Steena Dominica. "Statistical Techniques to Model and Optimize Performance of Scientific, Numerically Intensive Workloads." 2016. Web. 22 Apr 2019.
Steven Monteiro SD. Statistical Techniques to Model and Optimize Performance of Scientific, Numerically Intensive Workloads. [Internet] [Doctoral dissertation]. Utah State University; 2016. [cited 2019 Apr 22]. Available from: https://digitalcommons.usu.edu/etd/5228.
22. Saha, Biplab Kumar. Towards a Framework for Automating the Workflow for Building Machine Learning Based Performance Tuning.
▼ Recent interest in machine learning-based methods have produced many sophisticated models for performance modeling and optimi:,ation. These models tend to be sensitive to architectural parameters and are most effective when trained on the target platform. Training of these models; however; is a fairly involved process and requires knowledge of statistics and machine learning that the end-users of such models may not possess. This paper presents a framework for automatically generating machine learning-based performance models. Leveraging existing open-source software; we provide a tool-chain that provides automated mechanisms for sample generation; dynamic feature extraction; feature selection; data labeling; validation and model selection. We describe the design of the framework and demonstrate its effectiveness by developing a learning heuristic for register allocation of GPU kernels. The results show the newly created models are accurate and can predict register caps that lead to substantial improvements in execution time without incurring a penalty in power consumption. Advisors/Committee Members: Qasem, Apan (advisor), Ekstrand, Michael (committee member), Metsis, Vangelis (committee member).
Saha, Biplab Kumar. "Towards a Framework for Automating the Workflow for Building Machine Learning Based Performance Tuning." 2016. Masters Thesis, Texas State University – San Marcos. Accessed April 22, 2019. https://digital.library.txstate.edu/handle/10877/6343.
Saha, Biplab Kumar. "Towards a Framework for Automating the Workflow for Building Machine Learning Based Performance Tuning." 2016. Web. 22 Apr 2019.
Saha BK. Towards a Framework for Automating the Workflow for Building Machine Learning Based Performance Tuning. [Internet] [Masters thesis]. Texas State University – San Marcos; 2016. [cited 2019 Apr 22]. Available from: https://digital.library.txstate.edu/handle/10877/6343.
23. Lee, Chee Wai. Techniques in scalable and effective parallel performance analysis.
▼ Performance analysis tools are essential to the maintenance of efficient parallel execution of scientific applications. As scientific applications are executed on larger and larger parallel supercomputers, it is clear that performance tools must employ more advanced techniques to keep up with the increasing data volume and complexity of the performance information generated by these applications as a result of scaling. In this thesis, we investigate the useful techniques in four main thrusts to address various aspects of this problem. First, we study how some traditional performance analysis idioms can break down in the face of data from large processor counts and demonstrate techniques and tools that restore scalability. Second, we investigate how the volume of performance data generated can be reduced while keeping the captured information relevant for analysis and performance problem detection. Third, we investigate the powerful new performance analysis idioms enabled by live access to performance information streams from a running parallel application. Fourth, we demonstrate how repeated performance hypothesis testing can be conducted, via simulation techniques, scalably and with significantly reduced resource consumption. In addition, we explore the benefits of performance tool integration to the propagation and synergy of scalable performance analysis techniques in different tools. Advisors/Committee Members: Kale, Laxmikant V. (advisor), Kale, Laxmikant V. (Committee Chair), Snir, Marc (committee member), Heath, Michael T. (committee member), DeRose, Luiz (committee member).
Lee, Chee Wai. "Techniques in scalable and effective parallel performance analysis." 2010. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed April 22, 2019. http://hdl.handle.net/2142/14568.
Lee, Chee Wai. "Techniques in scalable and effective parallel performance analysis." 2010. Web. 22 Apr 2019.
Lee CW. Techniques in scalable and effective parallel performance analysis. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2010. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/2142/14568.
24. Nichols, Jennifer Chu. What School Leaders Need to Know About the Performance of High-Achieving Students on Standardized Tests.
▼ The No Child Left Behind Act (NCLB) of 2001 has changed the accountability of student achievement in American public schools. Since the enactment, achievement has increased for low-achieving students (Loveless, 2008). However, achievement for high-achieving students is leveling (Finn, Scull, & Winkler, 2011). This study identified and analyzed the performance trends of a cohort of students at the individual student level in mathematics and reading over four years. Students maintained, gained, lost, or never had high-achieving status during the study. Math lost high achievers overtime whereas reading gained high achievers overtime. Achievement status groups and trends across grade levels were examined by gender, ethnicity, and socioeconomic status to determine differences. There were differences in the performance of ethnic and economically disadvantaged groups but not by gender. This study highlights the need to examine achievement gaps among high achievers, not just low achievers, to ensure all students' needs are met. Advisors/Committee Members: Amine, Rayyan (advisor), Emerson, Michael W. (committee member), Busch, Steven D. (committee member), Indelicato, Anthony (committee member).
Nichols, Jennifer Chu. "What School Leaders Need to Know About the Performance of High-Achieving Students on Standardized Tests." 2013. Thesis, University of Houston. Accessed April 22, 2019. http://hdl.handle.net/10657/1026.
Nichols, Jennifer Chu. "What School Leaders Need to Know About the Performance of High-Achieving Students on Standardized Tests." 2013. Web. 22 Apr 2019.
Nichols JC. What School Leaders Need to Know About the Performance of High-Achieving Students on Standardized Tests. [Internet] [Thesis]. University of Houston; 2013. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/10657/1026.
25. Donoso Correa, Mario Ernesto. Geosimulations of urban growth, dasymetric mapping and population dynamics in northwest Florida, 1974 - 2025.
▼ Problem: this is the first time that the SLEUTH model has been applied to Escambia, Santa Rosa and Okaloosa counties. Here, dasymetric mapping and censuses from the simulations are performed, generating three scientific questions. First, how will the Cellular Automaton (CA) model depict the different urban and other landscape changes? Second, what results will these simulations produce if dasymetric mapping and censuses from the sky are applied under past, present and future conditions? Third, using this CA model, will it be possible to replicate alternative scenarios such as smart growth and urban sprawl? The answers to these questions are the main contributions of this research to the fields of geographic techniques and demographics in space and time. Methods: imagery classification was applied to Landsat MSS and TM according to Anderson Level I; accuracy classification was performed comparing the classified images against sample points taken from air photos and DOQQs; SLEUTH was implemented in a high performance computer; dasymetric mapping using Geolytics databases developed in ArcGIS and ERDAS Imagine; and finally, census from the simulations were generated using linear regressions and the allometric growth model. Results: the results were graphical and statistical outputs of all methods previously mentioned plus analyses of these maps and statistics about land cover and demographics. The SLEUTH simulations produced yearly graphical and statistical results from 1975 until 2025. Conclusions: urban expansion principally affects agriculture, rangelands, grasslands and forests; barrenlands also suffer from development, especially the beaches, showing unprecedented rates of urban growth. Smart growth provided an alternative strategy in which urban growth occurred in a more compact way, increasing its population density and decreasing the open space in the metro areas. Finally, the other scenariocalled urban sprawl simulated urban growth at a higher rate than normal, encouraging spontaneous and edge growth and lower population densities. Advisors/Committee Members: Fausto Sarmiento.
Donoso Correa, Mario Ernesto. "Geosimulations of urban growth, dasymetric mapping and population dynamics in northwest Florida, 1974 - 2025." 2008. Doctoral Dissertation, University of Georgia. Accessed April 22, 2019. http://purl.galileo.usg.edu/uga_etd/donoso_mario_e_200812_phd.
Donoso Correa, Mario Ernesto. "Geosimulations of urban growth, dasymetric mapping and population dynamics in northwest Florida, 1974 - 2025." 2008. Web. 22 Apr 2019.
Donoso Correa ME. Geosimulations of urban growth, dasymetric mapping and population dynamics in northwest Florida, 1974 - 2025. [Internet] [Doctoral dissertation]. University of Georgia; 2008. [cited 2019 Apr 22]. Available from: http://purl.galileo.usg.edu/uga_etd/donoso_mario_e_200812_phd.
26. Dangol, Sharad. Performance evaluation of high strength alloy steel cast connector under quasi-static load.
▼ High strength alloy steel cast connector refers to a bracing system to be used inJames L. Greene Science Center, Columbia University in New York. The castconnectors, as the name suggests, are the connection elements in a bracing system thatuses stainless steel rods as the braces instead of traditional steel sections.The bracing system was designed to support lateral wind load. The cast connectormaterial is A148 GR. 115/95 (ASTM A958, 2006). The nominal yield strength is f y = 95ksi, whereas the nominal ultimate strength is f u = 115 ksi. Although the material has veryhigh yield strength, its ductility is rather limited. Hence, limiting the use of theconnectors in a quasi-static load like wind load.This study evaluates cast connector performance under monotonic and cyclicloading. Experimental results are validated by a finite element (FE) model created inANSYS (Chapter 4).Initial proposed tests on the cast connector specimens showed linear performance.For loads of 2 and 2.5 times the design load (P = 275 kip), the test specimens exhibitedlinear behavior. Further tests with increased load were performed on a second specimen(Cast Connector 2) to obtain nonlinear behavior and connector failure modes. The nonlinearportion of the curve was not well developed as one would expect for steel, whichdemonstrated the brittleness of the material.
Dangol, Sharad. "Performance evaluation of high strength alloy steel cast connector under quasi-static load." 2013. Masters Thesis, University of Utah. Accessed April 22, 2019. http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/2325/rec/1828.
Dangol, Sharad. "Performance evaluation of high strength alloy steel cast connector under quasi-static load." 2013. Web. 22 Apr 2019.
Dangol S. Performance evaluation of high strength alloy steel cast connector under quasi-static load. [Internet] [Masters thesis]. University of Utah; 2013. [cited 2019 Apr 22]. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/2325/rec/1828.
27. Zhuo, Yue. IRLstack 3.0: High-Performance Windows Sockets.
▼ With the ever-growing volume and speed of Internet traffic, network applications place higher demand on packet I/O rates. Although 1-Gbps and even 10-Gbps Ethernet are widely adopted, achieving wire rate with small packets remains hindered by bottlenecks inside the TCP/IP stack. Improvements have been made for Linux, but there is still limited work in Windows. To bridge this gap, we build a new generation of our network driver IRLstack and show that it can achieve 10 Gbps wire rate (i.e. 14.88 Mpps), for both send and receive, with zero CPU utilization. This compares favorably to the fastest Linux versions, which typically saturate one or more CPU cores and often fail to achieve this rate in both directions. Advisors/Committee Members: Loguinov, Dmitri (advisor), Bettati, Riccardo (committee member), Reddy, Narasimha (committee member).
Zhuo, Yue. "IRLstack 3.0: High-Performance Windows Sockets." 2014. Thesis, Texas A&M University. Accessed April 22, 2019. http://hdl.handle.net/1969.1/154001.
Zhuo, Yue. "IRLstack 3.0: High-Performance Windows Sockets." 2014. Web. 22 Apr 2019.
Zhuo Y. IRLstack 3.0: High-Performance Windows Sockets. [Internet] [Thesis]. Texas A&M University; 2014. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/1969.1/154001.
28. Fang, Xudong. Oligomer-polymer gel spinning of high performance fibers.
▼ High performance polymer fibers are playing more important roles than before with increasing needs from more fields. However, the production and commercialization of such fibers are still limited due to high cost especially for those which are produced by gel spinning. The current gel spinning process relies on huge amounts of solvents for dissolution and extraction, leading to a slow, costly and environmentally unfriendly process. One major objective of this work is to optimize the gel spinning process to reduce cost and improve efficiency. The optimization methods include searching for new solvents based on an 'oligomer-polymer' spinning system and developing new extraction processes. UHMWPE fibers are used as a case for study. Results showed that a new oligomer solvent – polybutene – can be successfully used for more effective production of high-strength UHMWPE fibers with a mechanical solvent removal process. Phase diagram analysis was conducted to understand the process kinetics of the new spin system and generalize the findings. With realization of the first objective, a second objective is to extend the oligomer-polymer gel spinning process to the production of other high-performance polymer fibers. As of now, only very few polymers have been successfully produced by gel spinning, including polypropylene (PP), polyethylene (PE), poly (vinyl alcohol) (PVA) and polyacrylonitrile (PAN). In this work, the new oligomer-polymer process is used for producing high strength polyoxymethylene (POM) fibers for their potentially excellent engineering properties. With the 'oligomer-polymer' spinning system, a new 'solvent' has been found for POM and results showed that high strength POM fiber can be successfully gel spun. The relationship of processing with structure and property was studied to optimize the fiber performance. Advisors/Committee Members: Yao, Donggang (advisor), Wang, Youjiang (committee member), Deng, Yulin (committee member), Shofner, Meisha (committee member), Jacob, Karl I. (committee member).
Fang, Xudong. "Oligomer-polymer gel spinning of high performance fibers." 2016. Doctoral Dissertation, Georgia Tech. Accessed April 22, 2019. http://hdl.handle.net/1853/58593.
Fang, Xudong. "Oligomer-polymer gel spinning of high performance fibers." 2016. Web. 22 Apr 2019.
Fang X. Oligomer-polymer gel spinning of high performance fibers. [Internet] [Doctoral dissertation]. Georgia Tech; 2016. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/1853/58593.
29. Roy, Indranil. Algorithmic techniques for the micron automata processor.
▼ Our research is the first in-depth study in the use of the Micron Automata Processor, a novel re-configurable streaming co-processor which is purpose-built to execute thousands of Non-deterministic Finite Automata (NFA) in parallel. By design, this processor is well-suited to accelerate applications which need to find all occurrences of thousands of complex string-patterns in the input data. We have validated this by implementing two such applications, one from network security and the other from bioinformatics, both of which are significantly faster than their state-of-art counterparts. Our research has also widened the scope of the applications which can be accelerated through this processor by finding ways to quickly program any generic graph into it and then search for hard to find features like maximal-cliques and Hamiltonian paths. These applications and algorithms have yielded valuable design-inputs for next generation of the chip which is currently in design phase. We hope that this work paves the way to the early adoption of this upcoming architecture and to efficient solution of some of the currently computationally challenging problems. Advisors/Committee Members: Aluru, Srinivas (advisor), Apostolico, Alberto (committee member), Vuduc, Richard (committee member), Yalamanchili, Sudhakar (committee member), Bader, David A. (committee member).
Roy, Indranil. "Algorithmic techniques for the micron automata processor." 2015. Doctoral Dissertation, Georgia Tech. Accessed April 22, 2019. http://hdl.handle.net/1853/53845.
Roy, Indranil. "Algorithmic techniques for the micron automata processor." 2015. Web. 22 Apr 2019.
Roy I. Algorithmic techniques for the micron automata processor. [Internet] [Doctoral dissertation]. Georgia Tech; 2015. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/1853/53845.
30. Grant, Ryan Eric. Improving High Performance Networking Technologies for Data Center Clusters .
▼ This dissertation demonstrates new methods for increasing the performance and scalability of high performance networking technologies for use in clustered computing systems, concentrating on Ethernet/High-Speed networking convergence. The motivation behind the improvement of high performance networking technologies and their importance to the viability of modern data centers is discussed first. It then introduces the concepts of high performance networking in a commercial data center context as well as high performance computing (HPC) and describes some of the most important challenges facing such networks in the future. It reviews current relevant literature and discusses problems that are not yet solved. Through a study of existing high performance networks, the most promising features for future networks are identified. Sockets Direct Protocol (SDP) is shown to have unexpected performance issues for commercial applications, due to inefficiencies in handling large numbers of simultaneous connections. The first SDP over eXtended Reliable Connections implementation is developed to reduce connection management overhead, demonstrating that performance issues are related to protocol overhead at the SDP level. Datagram offloading for IP over InfiniBand (IPoIB) is found to work well. In the first work of its kind, hybrid high-speed/Ethernet networks are shown to resolve the issues of SDP underperformance and demonstrate the potential for hybrid high-speed networking local area Remote Direct Memory Access (RDMA) technologies and Ethernet wide area networking for data centers. Given the promising results from these studies, a set of solutions to enhance performance at the local and wide area network level for Ethernet is introduced, providing a scalable, connectionless, socket-compatible, fully RDMA-capable networking technology, datagram-iWARP. A novel method of performing RDMA Write operations (called RDMA Write-Record) and RDMA Read over unreliable datagrams over Ethernet is designed, implemented and tested. It shows its applicability in scientific and commercial application spaces and is applicable to other verbs-based networking interfaces such as InfiniBand. The newly proposed RDMA methods, both for send/recv and RDMA Write-Record, are supplemented with interfaces for both socket-based applications and Message Passing Interface (MPI) applications. An MPI implementation is adapted to support datagram-iWARP. Both scalability and performance improvements are demonstrated for HPC and commercial applications.
Grant, Ryan Eric. "Improving High Performance Networking Technologies for Data Center Clusters ." 2012. Thesis, Queens University. Accessed April 22, 2019. http://hdl.handle.net/1974/7502.
Grant, Ryan Eric. "Improving High Performance Networking Technologies for Data Center Clusters ." 2012. Web. 22 Apr 2019.
Grant RE. Improving High Performance Networking Technologies for Data Center Clusters . [Internet] [Thesis]. Queens University; 2012. [cited 2019 Apr 22]. Available from: http://hdl.handle.net/1974/7502.


File this under things no one could ever expect to happen: Apparently Hollywood superstar Margot Robbie (you know her for her work in Neighbours, Suicide Squad, and most recently, the Oscar-nominated I, Tonya) was once—and kind of still is—a huge metal dork. In a new interview with BBC Radio 1, the Aussie actress reveals a childhood fascination with the heavy music genre, namedropping Metallica, Thrice (who aren't metal, but I'll let her have this one), and Bullet for My Valentine. It's incredible.
That's not all! Nick Grimshaw, beloved BBC Radio 1 host and maybe-probably-not-but-it-is-nice-to-dream ex-boyfriend to One Direction heartthrob Harry Styles (educate yourself in 1D gossip, dang) knew all this ahead of time, and asked Bullet for My Valentine to dedicate a song to her at their Saskatoon, Canada tour date. They did, he showed her the footage, she was delighted, the whole thing was very strange, but I'm goddamn delighted, too.
Check it out at the 6:00 minute mark above.
What's Going On With Margot Robbie?


Westfield Health donates £5k to Changing Faces.
We've donated £5,000 to Changing Faces, a charity offering support to people with disfigurements, to help boost its service for people across Yorkshire and the Humber.
The funding will help deliver practical and emotional support for people living with conditions, marks or scars that affect their appearance.
The charity helps people to understand their condition and provides support to people coping with the psychological and social effects of disfigurement, and their families. One of its other objectives is to transform public attitudes towards people with disfigurement, ensuring they're given fair treatment and equal opportunities in society.


text:
News Oct 4, 2017 7 comments
Key facts about coccidiosis
Keeping on top of coccidiosis is crucial for the welfare and performance of a poultry flock, as Jake Davies discovers.
The cost of coccidiosis to the poultry industry is massive. A 1999 paper put its global cost to production and control at more than $5bn each year. Subclinical cases will hit profitability through poor feed conversion, while damage to the gut wall makes it easy for more virulent challenges to take hold, like necrotic enteritis.
As such, every farmer should be up to speed on the mechanism that causes cocci to harm birds, and the best ways to prevent it responsibly, according to Monita Vereecken of pharmaceutical outfit Huvepharma. "If you want to control the disease, you need to know the disease," she says.
Photos and illustrations: Jake Davies
Coccidiosis is both host specific and site specific – meaning that individual strains can be relatively easily identified. Indeed, anyone able to dissect a bird can learn the basics, identifying the obvious features of each species in an afternoon.
The sub-species are all part of the Eimeria family, and present in distinct ways. E. tenella, for example, will colonise the ceaca, causing it to swell with blood in the worst cases. E. acervulina is less pathogenic, but can hamper performance without causing any clinical symptoms – and so push up feed costs. It also makes for wetter droppings, reducing litter quality as well.
"The lifecycle of coccidiosis looks simple, but is actually quite complex," says Ms Vereecken.
"You have asexual and sexual multiplication, and different stages of the parasite invade and cause damage. That is why you cannot grow coccidiosis in the lab – if you want to perform tests, you have to do it in live birds."
In essence, birds ingest a sporulated oocyst, which is activated by the warm, humid environment of a poultry shed.
Those little oocysts are exceptionally efficient multipliers – one can become thousands in a matter of days.
They typically take five to seven days – depending on the species – to undergo this reproductive cycle, and while inside the guts of chickens, they will be damaging the gut wall.
If left unchecked, cocci populations will simply build and build, causing more and more damage to gut walls.
As mentioned, each species has an effect on a distinct region of the intestines (see illustration below).
Detecting the severity and strain of the coccidiosis, fortunately, remains relatively straightforward, using the Johnson and Reid scale.
"It is an interpretive, but fairly standardised method," says Ms Vereecken.
The first tip she offers is to conduct the biopsy as soon as a bird is killed – E acervulina lesions are so small that they will degenerate very quickly.
"It's also important to take your time, and look at the entire gut, not just the duodenum."
As soon as the gut is removed from the bird, the outer wall should be inspected for signs of E maxima, and when eventually opened, care should be taken not to overly disturb the content of the guts as this can provide clues as to how the bird was processing feed.
When in the gut, it's important to score the highest lesions that you find, and use those to build a picture of the outbreak.
E. acervulina in its most severe form is difficult to detect – the white spots characteristic of milder outbreaks will merge into a white plaque.
"The highest lesions are sometimes the ones that you will miss."
It also is important not to be too rough with the dissection as it is possible to scrape lesions away while opening the guts.
The purpose of regularly autopsying birds within a flock is to detect whether the control measures – coccidiostats and cleaning regime – are effectively suppressing the health challenge.
Once a representative sample has been taken, a total mean lesion score can be generated that will give some indication of the severity of the outbreak.
Cocci control
• A key measure in controlling coccidiosis is effectively cleaning sheds at turnaround – burning floors is an effective way to reduce the load, but will not remove spores on walls, feeders and drinkers
• Typically coccidiostats, a class of ionophore, will be employed to suppress coccidiosis sporulation
• Chemical treatments can also be employed in rotation
• Vaccines are also available, but to date are less cost effective for primary broiler production. They are typically used on longer-living birds.
Coccidiosis – where it colonises (Mouse over icon in illustration below for more information)
Effective health control beats necrotic enteritis
The key predisposing factor for necrotic enteritis in poultry flocks is coccidiosis, but there is a host of other ways the risk of infection can be mitigated.
"You can inoculate a bird with millions of clostridium pefringens bacteria and not see anything," says Prof Filip Van Immerseel of Ghent University. "The predisposing factors are very important – by eliminating them you can avoid necrotic enteritis."
The condition is caused by the necrotizing toxin released when Clostridium P overcomes more commensal bacteria in the gut and begins to dominate the microbiota.
Clostridium relies on external sources of protein, so one significant risk factor is high protein diets.
Stress is also a known cause – both heat and stocking density. Necrotic enteritis is almost unknown is low-stocked systems.
Mycotoxins in feed – even below maximum suggested EU standards – have been found to significantly increase the risk of necrotic enteritis.
The disease is also rarely discovered outside of two-to-four weeks, a period in which birds' immune systems are naturally lower.
"The most easy option is to kill the bacteria," says Prof Van Immerseel. Antibiotics are the only treatment that will destroy the bacteria totally, but there should be an effort to find alternatives to suppress the infection. "Currently there is no feed additive or vaccine that reduces it to zero," he adds.
Ionophores help, but it is the prevention of coccidiosis that offers the best protection.
A focus for the future of bird health in general will be in ensuring the gut microbiota is balanced, and thereby preventing clostridium gaining a foothold in the gut.
But the key focus for farmers should be preventing the circumstances from which it arises in the first place by using an effective coccidiosis control programme.
*This article is based on findings from a poultry health workshop hosted by veterinary medicines firm Huvepharma.
Jake Davies
Freelance Journalist
Rufaro Mucheche
HELPFUL INDEED, THANK YOU
MR. ONIYELU
Very informative and educative. Thank you.
O.T Oludare
Very informative!
Dr. Ashraf Ali Qureshi
Very well explained. Thanks
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Comfy Baby Time's Child Safety Harness Stops Your Kids From Getting Lost!
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Comfy Baby Time was founded by parents who are now grandparents who know the experiences other parents have and want to make sure your children, toddlers and babies are safe and happy.


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David Lavis was State Manager of H.B. Selby, scientific and medical suppliers 1966-1985. After his retirement from Selbys he established a small special equipment supply company of his own, Daybar Technical Supplies.


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