Wolfgang's high school graduation has turned into a series of numbers, and a lot of counting. The ceremony is on Saturday, and I am tearing up just thinking about that.
Thirteen years since the first day I dropped him off at Bennett Elementary School to go out into the world and learn things I could not teach him. Thirteen years since I bought him his first backpack (Transformers, if I recall correctly) and packed him a lunch in his new lunchbox.
Thirteen years of school supply lists, parent-teacher conferences, after school activities and homework-checking. Thirteen years of signing field trip permission slips and volunteering with the PTA. Thirteen years of fabulous teachers, funny mom friends and first (and last) days of school.
Twelve. Number of times I have run my hands over the sash he will wear for his graduation (just today). Number of times I have burst into tears (also, just today), thinking of what he was like as a tiny kindergartener, with his proper posture and his vast knowledge of planets.
Number of times I have gotten a lump in my throat because I don't know what comes next, but I'm really excited to see what happens.
Eleven. How many graduation episodes of television shows I have watched to try and make myself immune to graduations altogether, so I don't cry.
Ten. The number of times I have checked Wolfgang's epic to-do list. Also, number of times I have texted him in the last 24 hours to remind him of his to-do list. Also, the number of times he has rolled his eyes so hard at me that I'm worried they will stick like that up inside his skull.
Probably also the number of times I've sighed in the past week, trying to wrangle tickets for graduation, grad party plans, whereabouts of the actual human graduating and the schedule of grad events.
Nine. The grade Wolfgang was entering when I started to panic about graduation.
It seems like a far-off dream until your baby actually STARTS HIGH SCHOOL. You have this adorable tiny human who you've raised and nurtured and fed and tried to not yell at when they wreck your new dress with their muddy handprints and then all of a sudden it's a race to high school commencement ceremony and they are an adult and leaving you and yes I am crying right now, hush.
Eight. How many graduation-related posts I've attempted to write and had to abandon because I was crying so hard, I gave myself a headache. Number of posts I have in my drafts folder that I may have to wait until NEXT graduation season to complete.
Also, the number of pretty awesome kids who have come up to me to hug me in the past week to tell me how much they appreciate the times I've chaperoned a field trip, or let them text me in the middle of the night with questions about life, or took their photo for football.
The number of faces of growing adults I've held in my hands in the past week and said "you are so welcome, I am so proud of you" to.
Seven. Seven years of awkward band concerts, with Row Row Row your Boat played in 4 different keys and tempos. Seven years of letter grades to worry about (and for me to obsessively check online).
Seven years since I've been able to help Wolfgang with his math homework.
Seven years of after-school activities and clubs, of "let me do it, mom!" and trying to run his schedule on his own. Seven years of multiple teachers every year, of "which class is your 5th period?" and really confusing Back To School nights. Seven years of philosophical discussions on whether or not I should be in the PTA, and volunteering quietly for any and everything I had time for.
Six. Number of years I have done this alone, since my now-ex-fiancé and I split. Number of years I worried about how to pay for yearbooks and new shoes and new backpacks. Number of years I've lost sleep over how to encourage Wolfgang to do his homework (and actually hand it in).
Number of years I've worried I'm screwing him up, and number of years I've realized that he's a good human and I've done ok as a mother.
Five. Five days until the graduation ceremony. Five more days of him being my "baby", before he dons that cap and gown and shakes the principal's hand and gets his diploma. Five more days of me ugly crying every time someone mentions graduation, or I look across the room at his cap and gown hanging.
Four. I can count the number of days we have left in high school on one hand.
Four more opportunities to pack a lunch, bundle Wolfgang up into the car and ferry him to school. Four more days to check his homework, to make sure he gets up on time, to remind him to eat breakfast. Four more days until we are done with public school.
Four more days of me yelling "HAVE A GREAT DAY I LOVE YOU, MAKE GOOD CHOICES!" like I do most mornings as he closes the door behind him. Four.
Three. Number of boxes of Kleenex I have blown through while crying in the past month, thinking of the end of all of this.
One. One more "last" event, a choir concert. One more event before graduation for me to embarrass Wolfgang thoroughly with my sobbing in public. One more choir concert. One more "senior recognition". One more award ceremony, one more band picnic, just one more.
Countless. Number of memories I have of my baby. Of the time he corrected his kindergarten teacher (who had hung the solar system incorrectly). Of the first time I heard him sing on stage (playing Lumiere in Beauty and the Beast). Of all of the plays, the band concerts, the football and soccer games, the homework.
I am so incredibly proud of my son, of everything he's done. I'm excited to watch him get his diploma this weekend and see where life will take him.
Holidays as a single mum are hard, no matter which way you slice it. You can get extended family involved, but when it all boils down to it: all the planning, the paying and the execution are solely on your shoulders.
It can be a bummer, I totally understand. 2/3 of the Mothers' Days I have celebrated as a mom have been as a single mom. It's hard some days!
But, as with all things, you get to choose how to handle it. You can choose to be angry about your situation and sulk, or you can choose to make the best of it.
There's no reason why you should skip Mother's Day if you choose to celebrate (and opting out is totally fine as well!).
Here's a couple of tips to help you make Mothers Day great!
* Get your kids involved. Depending on their ages, your kiddos can handle making breakfast, or cleaning the kitchen or the bathroom or if they're older, they can even manage your smalls while you go to a movie!
* Keep it simple. We don't need huge parades of gifts and lavish things showered upon us (every mom DESERVES that, but it's ok if we don't get it!). If my kids make me a card and give me an hour by myself (without questions) in my office to work on my calligraphy or my painting, I'm happy with that.
* Get it pre-made (or go out for it). Even if you're just getting pizza, it's a meal you didn't have to make. Buy one of those meal kits at the store that you just need to heat up (bonus points if the kids can heat it up themselves)! Make Mothers' Day low impact for yourself.
* Don't compare. Zero good things come from saying "but Mary got blah blah blah for Mothers' Day and I only got xxxx." Mary is not you (unless your name is actually Mary, then I'm talking about a different Mary). You are not Mary. Comparing your situation to Mary's is like comparing that one time you did karaoke to that guy who sings showtunes at the local supermarket while he shops. They both have their benefits, but they're totally different situations.
When push comes to shove, yes you have to make your own Mothers Day, but that doesn't mean you cannot make it awesome.
Love to all of my single moms out there this Mothers Day!
We have never really had a garden in the various homes we've lived in.
I think the last time we had a vegetable or herb garden at a house I inhabited was back in the 80s….so it's been a while.
This home we live in now is a veritable garden paradise. There are huge established plum and fig trees, two big raised veggie beds, an herb garden and lavender, sage and rosemary all over the side of our house.
The rosemary in particular is getting a bit out of hand right now. It's just finished flowering, so it's a bit raggedy looking, but all three bushes are enormous. I don't know that I could use all of that rosemary in a month, if we ate it with every meal.
But I'm making a valiant effort.
In the past, I have let things die in the few pots I have dared to plant of edible things. I am not sure of the base reason, but I suppose my past (bad) habit of laziness would have had something to do with it.
This year, I am determined to DO THE THINGS. To take advantage of the opportunities I am given, rather than letting them pass me by. To use the tools and resources that I cultivate or grow or harvest or purchase and not let them rot in my fridge.
So we've had a few get-togethers over the past few REALLY hot days, where we needed something a bit more fancy than the norm to drink.
And a few weeks ago, I just happened to unearth my mother's recipe for rosemary lemonade.
So after one batch that had WAY TOO MUCH SUGAR and one batch that had some weird metallic taste and then one with too few lemons, and then one really terrible foray into trying to use the smaller lemons to save a couple of dollars….I have conquered the recipe for one of the best tasting beverages I have had, and super thirst-quenching too!
And because I love you and want you to be happy – I am sharing it with you.
You want to make this at least 2-3 hours in advance to let the flavors mingle together.
Store any leftovers (if you have any!) in the fridge.
I like to let the rosemary sit in the pitcher, both for decorative and flavor reasons.
Put 1 cup of water and 1 cup of sugar in a saucepan on high heat, cook just until sugar dissolves. Add 2 sprigs of your rosemary once you turn the heat off, and let it cool.
Add lemon juice, 8 cups of water, remaining rosemary and 1/2 cup sugar to pitcher (or sun tea jar – makes serving easy).
When sugar syrup cools, add it (and the rosemary) to the pitcher.
Refrigerate for 2-3 hours before serving to allow the flavors to settle.


A. Backlit subject: Place your subject (preferably a person) in front of a bright window and take a photo of them.
B. Fast subject: Have your subject indoors or in the shade and have them move around quickly. If you have room in the space, have them run back and forth. If space is limited, just have them wave their arms up and down. Take photos of them doing these actions.
C. Subject is not in the foreground: Set up a shot so that your subject (it can be a person or an object) is not the closest thing to the camera. For example, a bird in a cage, or a person standing at the back of the room and a table in the middle of the room.
D. High noon: Take a shot of someone outside on a sunny day around noon. Observe the harsh light and unflattering shadows created on your subject's face.
E. Light and Dark in one shot: Take a shot on a bright day that includes the bright blue sky and a part of the ground with shadows on it.
F. Night shot: Take a photo of someone at night time standing in front of a location that doesn't have very much light.


WATCH - #InterTalks Ep. 9 - Sampdoria 0 - 1 Inter Review: "VAR Is A Joke"
Inter's away fixture against Sampdoria ended just like the match against Tottenham did: a late winner in the dying seconds of the match after a lot of drama and controversy concerning the VAR which this episode of #InterTalks analyzes.
Anthony analyzes the match as he goes through the decisions made by the VAR referees and the inconsistency as to how this technology is used when Inter are concerned before previewing tomorrow's Serie A clash against Fiorentina at the Stadio Giuseppe Meazza.


Researchers will use the labs to improve solar cell technology, battery efficiency, magnesium implants for patients, and water sensing and purification.
RMIT Deputy Vice-Chancellor Research and Innovation and Vice-President, Professor Calum Drummond, said the facilities were set to strengthen the University's research achievements in areas that would directly benefit industry and the community.
"Our new labs will give us greater ability to quickly find industry-relevant solutions at a time when the need for energy efficient and high performing materials and advanced manufacturing is increasing exponentially," he said.
The lab opening coincides with RMIT's new partnership with the Advanced Manufacturing Research Centre at the University of Sheffield to collaborate and exchange expertise across advanced manufacturing and engineering.
Enabling Capability Platform Directors Professor Rachel Caruso and Professor Ivan Cole and Deputy Vice-Chancellor Research and Innovation and Vice-President, Professor Calum Drummond.
The Rapid Discovery and Fabrication Laboratory will be led by Advanced Manufacturing and Fabrication Enabling Capability Platform Director, Professor Ivan Cole.
The Advanced Porous Materials Laboratory will be led by Advanced Materials Enabling Capability Platform Director, Professor Rachel Caruso.
The facilities and equipment are expected to enable high-throughput experimentation, where large numbers of tests run simultaneously, as well as advanced computational modelling.


As one way to mark the HPS Kent group's 30th Anniversary in 2018 we asked our members to vote for their personal Top 5 plants. This was not restricted to herbaceous perennials but could encompass the whole range of plants from trees, shrubs, perennials to bulbs and corms. This proved to be a very interesting exercise and quite a challenge. After an initial flurry of Top 5 voting things went very quiet and so we chivied people up and extended the voting period by a month. The main remark from our members was how difficult it was to come up with a definitive Top 5 and that it was liable to change daily! I can well understand this. The other taxing problem was to think about plants from other seasons of the year and not to focus on the current season when you were deciding your Top 5. Personally I tried to vote for plants which either contributed to the garden for a long time or at different seasons throughout the year. Also special plants might be chosen because of a memory or because, for example, they were harbingers of spring.
Voting closed at the end of January and the Top 30 was compiled from the I97 different plants which had received votes.
Thank you to everyone who voted for their own Top 5. I think it is a true reflection on the members' knowledge and passion for plants that we have such a wide variety of plants voted for. I hope I have done justice to the overall idea.
Rather than publish the whole list in one go we thought we'd have some fun. We'll announce the first two, that's numbers 30 and 29, at our Special Spring Meeting on 25th March and then on the website. Thereafter, there'll be one a day on the website finishing with Number 1 at our meeting on 22nd April. This will coincide with publication of the whole list in the Spring Newsletter.
We hope you enjoy following the countdown.
There are a few surprises that should set you talking!
Really exciting, now I still have to wait till Sunday….


Peter Parker loves his new powers. But maybe a little too much?
I enjoyed this Spider-Man short. I thought the other footage was integrated very well, visually. It would have been cooler to have more concrete stuff happen in the flashbacks but you can only work with what you have. As it is, I think it still works well. Good edit, enjoyable and without any major issues.
Excellent. Slight plot issue with the Bank already having been robbed by the time spidey shows up, but otherwise a really strong alternate universe take on Spiderman.


George Washington Papers, Series 4, General Correspondence: Seth Banister to Benedict Arnold, August 5 . August 5, 1780. Manuscript/Mixed Material. https://www.loc.gov/item/mgw424684/.
(1780) George Washington Papers, Series 4, General Correspondence: Seth Banister to Benedict Arnold, August 5 . August 5. [Manuscript/Mixed Material] Retrieved from the Library of Congress, https://www.loc.gov/item/mgw424684/.
George Washington Papers, Series 4, General Correspondence: Seth Banister to Benedict Arnold, August 5 . August 5, 1780. Manuscript/Mixed Material. Retrieved from the Library of Congress, <www.loc.gov/item/mgw424684/>.


Speaking at a tribal rally in Karnataka's Raichur district, the Congress president attacked Prime Minister Narendra Modi over unemployment of the country's youth and disrupting rural economy through GST and demonetisation.
Congress president Rahul Gandhi on Monday asked Prime Minister Narendra Modi to explain how Bharatiya Janata Party (BJP) president Amit Shah's son's company earned profits, while small traders across the country shut shop after demonetisation.
Gandhi was speaking at a tribal rally in Raichur district's Devadurga as a part of the Janashirvada Yatra.
Goods and Services Tax (GST), which he ridiculed as the Gabbar Singh Tax.
"Small traders are shutting shop, but there is only one company that grew its business from Rs 50,000 to Rs 80 crore. That belongs to Amit Shah's son," Gandhi said, referring to Jay Shah.
"You tell youngsters to become entrepreneurs and you don't give them employment. But for your friend Amit Shah's son, you have set up a start-up," he said.
Gandhi said India was losing in the competition against China because everywhere one looked, one could only see products made in the neighbouring country.
"Shirt, cameras, cars; everything is made in China," he said, adding that while that country created 50,000 jobs a day, the Modi government could only manage 450 per day.
The Congress president likened the Prime Minister's leadership to a batsman who looks at the wicketkeeper, unlike Sachin Tendulkar, who faces the bowler.
"Siddaramaiah looks at the ball and Modi looks at the wicketkeeper when the ball comes. Mistakes happen because of this. Demonetisation happens. Farmers, adivasis are affected by this and Gabbar Singh Tax is introduced," he said.
Reacting to Gandhi's jibe, senior state BJP leader KS Eshwarappa said these were desperate attempts to discredit the good work done by Modi. "Gandhi himself is an unemployed person, which is why he is making such comments," Eshwarappa said.
"Clearly, he has not studied the various measures taken by the Modi government to promote employment," he added.


text:
England's Alex Chamberlain- Oxlade, right, steals the ball from Ecuador's Carlos Gruezo in the second half of a friendly soccer match in Miami Gardens, Fla., Wednesday, June 4, 2014. The game ended a 2-2 tie. (AP Photo/El Nuevo Herald, Hector Gabino)
Oxlade-Chamberlain Injury Update: Hodgson Will Wait Till 'Very, Very Last Moment' Before Deciding
MIAMI SHORES, Fla.—England coach Roy Hodgson will take the decision on Alex Oxlade-Chamberlain's World Cup participation right down to the FIFA deadline.
England has until 24 hours before opening its campaign in Brazil against Italy on June 14 to decide whether to replace Oxlade-Chamberlain in the 23-man squad.
The Arsenal midfielder sustained ligament damage in his right knee during England's 2-2 draw against Ecuador at the Sun Life Stadium in Miami Gardens on Wednesday.
After training ahead of Saturday's final warmup game against Honduras, Hodgson confirmed that the decision on Oxlade-Chamberlain would be taken "at the very, very last moment."
Hodgson added: "Let's hope that it is not that serious and it won't even be a question of him leaving us."
10hr By Reuters

redpajama_set_name: RedPajamaCommonCrawl


text:
Source: Committee on the Exercise of the Inalienable Rights of the Palestinian People (CEIRPP)
UNITED NATIONS INTERNATIONAL MEETING
ON THE QUESTION OF PALESTINE
Engaging for peace – the International Year of Solidarity with the Palestinian People
Quito, 25 and 26 March 2014
CHAIRMAN'S SUMMARY
The United Nations International Meeting on the Question of Palestine, hosted by Ecuador and organized under the auspices of the Committee on the Exercise of the Inalienable Rights of the Palestinian People, examined the support by Latin American and Caribbean countries for a comprehensive, just and lasting settlement of the question of Palestine, and the role of non-governmental actors in Latin America and the Caribbean in promoting a permanent settlement of the conflict.
Representatives of Governments, intergovernmental organizations, including various United Nations bodies, and the civil society, together with expert speakers from Brazil, Argentina, Peru, Uruguay, Israel, Palestine and the United States shared their expertise at the Meeting.
In the opening session, the Vice-Minister for Foreign Affairs and Political Integration of the Ministry of Foreign Affairs and Human Mobility of Ecuador, representing the host Government, expressed his country's support for the Palestinian people and for solidarity activities in the framework of the 2014 International Year of Solidarity with the Palestinian People. He stressed that Ecuador, as Brazil, was one of the first in Latin America, in 2010, to recognize the Palestinian State within 1967 borders. The opening of the Palestinian Embassy in Ecuador in January 2014 and the planned opening of an Ecuadorian Embassy in Palestine in the next few weeks would strengthen the ties between our peoples, he said. The question of Palestine was of constant concern for Ecuador, especially when Israel stepped up actions that contributed to mistrust and undermined the current renewed round of negotiations. Recalling that the United Nations General Assembly, in its resolution 68/12 of 26 November 2013, proclaimed 2014 the International Year of Solidarity with the Palestinian People, the Vice-Minister said that Ecuador hoped that Palestine would soon be admitted as a full member of the United Nations, and reiterated its unconditional support for the cause of Palestine, which must result in the exercise of its inalienable right to self-determination and freedom, in an independent Palestinian State.
The Secretary-General of the United Nations in his message to the Meeting stressed that the UN remained committed to a peaceful settlement of the question of Palestine resulting in the two-State solution. The current renewed round of peace negotiations has presented a rare and important opening to advance the two-State solution. He called on both parties to act to reach an agreement, even if it required painful concessions. He said he was encouraged by the commitment of the Arab leaders to uphold the 2002 Arab Peace Initiative. He remained deeply troubled by Israel's rapidly expanding settlement activity in the West Bank, including in East Jerusalem. Increasing incidents at Temple Mount/Haram Al Sharif were deeply troubling, as they could be perceived as serious acts of incitement in the wider region. The Secretary-General expressed concern by the recent escalation of violence between Gaza and Israel and the unacceptable rocket firing into civilian areas. He called for maximum restraint by all sides to allow the implementation of the Agreement on Movement and Access and the Security Council Resolution 1860 (2009). Concluding, the Secretary-General expressed his hope that the International Year of Solidarity with the Palestinian People would create an environment favorable for fulfilling the collective responsibility towards the Palestinians.
The Chairman of the Committee expressed appreciation for the opportunity to be back in the Latin American and Caribbean region after the meeting in Montevideo in 2011. Recalling the wave of announcements of recognition of the State of Palestine by Latin American countries which started in December 2010, he underscored that Latin America was a region where Palestinian and Jewish diasporas coexisted peacefully. Moving on, the Chairman drew attention to the fact that settlement construction in 2013 more than doubled compared to 2012, and that a week before this Meeting, the Israeli Defense Ministry announced it would proceed with plans to build 2,269 new homes in settlements in the West Bank. Settlements were a clear violation of Art 49, Fourth Geneva Convention, he reiterated, and recalled the wave of announcements by European banks and pension funds severing ties with Israeli companies involved in illegal settlements. Speaking of the UN General Assembly proclaiming last November the year 2014 as the International Year of Solidarity with the Palestinian People, he pointed out that the objective of the Year was to raise international awareness of the main issues of the question of Palestine, and to promote peace. The Committee counted on the support of the Governments and peoples of Latin America and the Caribbean in undertaking various initiatives of solidarity with the Palestinian people.
The Permanent Observer of the State of Palestine to the United Nations, representing the President Mahmoud Abbas, thanked the people of Ecuador and the Committee on the Exercise of the Inalienable Rights of the Palestinian People for their continued efforts in support of the Palestinian cause. He said this was a critical moment in the struggle of the Palestinian people, since the ongoing round of negotiations stalled despite the Palestinian side having acted in good faith and upholding its commitments. He pointed out that the change in its legal status by General Assembly Resolution 67/19 of 29 November 2012 also entitled Palestine to access international legal instruments and join UN bodies. He stressed that Israel continued its illegal actions, resulting to a 123-percent increase in settlement construction in 2013 as compared to the year before. He called for Israel to negotiate in good faith, be willing to cross the bridge and desist in its occupation. The international community, including Latin America and the Caribbean, had a collective responsibility to take political, diplomatic and legal steps necessary to hold Israel accountable for its actions, he concluded.
In his keynote presentation, the United Nations Assistant-Secretary General for Political Affairs pointed out that Palestinian and Israeli interests were not mutually exclusive, indeed they depended one on another. Neither side would fully benefit from the peace, security and self-determination it deserves if the other side did not do so as well. He said that the parties were now at a moment of truth; a solution to the conflict was in reach and had to be seized. The status quo was not only unsustainable, it was continually deteriorating. The fragile security situation on the ground underscored the urgency of finding a solution to the conflict. He said that the sanctity of holy sites of all faiths must be fully respected and incitement or provocations from any quarter must cease. Drawing attention to the increasingly worrying security and humanitarian situation in Gaza, he stressed that the only way to sustainably solve the Gaza predicament was by reintegrating it into one Palestinian polity in the context of serious progress towards the two-State solution. Concluding, he reiterated that in this Year of Solidarity with the Palestinian People, the UN hoped to witness a success of direct negotiations which would bring about a comprehensive settlement based on a two-State solution. Such a peace would provide the Palestinian people with the opportunity to be free and live in dignity which they so rightfully deserved.
A number of representatives of Governments and intergovernmental organization expressed their solidarity with the Palestinian people, support for the ongoing renewed round of peace negotiations spearheaded by the US Secretary of State Kerry, the hope for the creation of the Palestinian State on pre-1967 borders, with East Jerusalem as its capital, and the need for Israel to abide by international law.
The participants then reviewed the obstacles and opportunities to advancing peace between Israelis and Palestinians; the support by Latin American and Caribbean countries for a comprehensive, just and lasting settlement of the question of Palestine; and the role of non-governmental actors in Latin America and the Caribbean in promoting a permanent settlement of the conflict.
It was recalled that a solid majority of both Israelis and Palestinians have expressed a preference for a two-State solution to the conflict in virtually every poll and survey over more than two past decades. Despite the enormous frustrations resulting from a lack of peace, these majorities remained committed to this goal. The Arab League, through its Arab Peace Initiative, had unanimously expressed the Arab consensus in favor of this as well. It was pointed out that with the exception of a few outliers internationally and in any given society, the whole world essentially agreed on both the two-State solution and its fundamental outlines: a Palestinian State alongside Israel based on the 1967 borders with mutually agreed land swaps and its capital in East Jerusalem; a fair and just resolution of the refugee issue; and full regional acceptance, recognition and integration of Israel in the Middle Eastern family of nations; and guarantees for Israel's security.
The first, and perhaps most far-reaching, of the obstacles to peace was a fundamental lack of trust that political leaders on both sides confront, a number of participants believed. The agreed-upon final status issues themselves presented another serious set of challenges to advancing peace, because – despite significant progress in bridging the gaps over the past quarter century – the distance between the parties on these specific issues, borders, settlements, Jerusalem, refugees, water and security, remained real and substantive. Participants agreed that there were difficult choices to be made, but the prevailing political conditions rendered them far more difficult. Finally, participants also brought up the issue of regional dynamics, which have also proven to be an impediment given the repeated interference in Israeli-Palestinian dynamics, and internal Palestinian politics, by various regional actors, some of whom were not committed to a two-State solution. Adding to that was the ongoing period of protracted instability and change in the Middle East and North Africa, due to which the Israeli-Palestinian issue had receded as an immediate priority for much of the international community.
Nevertheless, participants were unanimous in that the prospect for a real engagement by significant regional players in the Israeli-Palestinian political process in a positive manner was foreseeable, and in that the international community as a whole should continue to develop and intensify efforts to de-incentivize Israel from any further illegal activities in the Occupied Palestinian Territory.
A participant representing the WFP drew attention to the humanitarian and economic situation in the West Bank and Gaza as a result of Israeli policies and practices. 1.57 million People in Palestine were food insecure - 19 percent in the West Bank, 57 percent in the Gaza Strip. 45 percent (or 2 million people) had restricted access to primary health care, 28 percent (1.25 million people) were unemployed, 22 percent (0.98 million people) received less than 60 liters of water per day. There was a 25-percent increase in home demolitions and there were 12,000 outstanding demolition orders, he stressed. Humanitarian needs in Palestine were a result of severe restrictions on livelihoods and economic activity on the part of Israel, he said, calling on Israel to stop its illegal policies and practices.
Assessing the viability of the two-State solution, a speaker from Israel's largest peace movement "Peace Now" first gave an overview of the Israeli settlement activity from 1977 to 2013, and then outlined the major threats to the two-State solution such as the construction in "Ariel", in E1 (planned), and "Efrat" settlements. Relying on the results of a poll conducted by the University of Maryland in December 2013, he illustrated the support of both the Israeli and Palestinian public for a peace agreement. He pointed out that in the current Knesset 72 members were in favor of a peace deal, 41 against, and 7 abstain, and called on Prime-Minister Netanyahu to use this majority support of the Israeli public and of the majority of the Knesset to make a peace agreement. He stressed that only 1.8 percent of the total Israeli population would be affected by an evacuation (according to the Geneva Initiative Plan), and believed that the Israeli public should be told more often of the benefits a peace agreement would bring to the Israeli economic and diplomatic standing internationally.
Moving on to the role of the Latin American and Caribbean countries in the peaceful resolution of the conflict, participants astutely observed that through its Arab and Jewish diasporas, Latin America was linked to Israel and Palestine with strong ties - cultural, ethnic, economic, religious, political, and moral. Participants thanked all Latin American and Caribbean countries that have recognized the State of Palestine, and called on countries that have not done it so far to do so. It was stressed that Latin America and the Caribbean were against the occupation and its dire consequences, but not against Israel and its people, and that this should be clear. Participants praised that among the Latin American countries Brazil had been exemplary in its solidarity with the Palestinian people and played an important role since the very beginning of the Israeli-Palestinian conflict. Reflecting on the complexity of the relationship between Brazil and the Middle East region however, a participant raised a question of Brazil's arms trade deals with Israel, which made the country Israel's biggest partner in Latin America, and the second biggest in the world.
Another discussion ensued on whether the Arab and Jewish diasporas in Latin America were part of the problem or part of the solution. It was observed that diasporas maintained a sustained concern about the situation in their countries of origin, and sometimes, instead of "exporting" good experience of coexistence to the Middle East, diasporas were perceived as "importing" conflict to Latin America, by virtue of a so-called "long-distance nationalism". However, by and large, there was a tradition of coexistence between the Arab and Jewish diasporas in Latin America through shared neighborhoods, clubs, banks, joint businesses. Jews and Palestinians who lived in Latin America created mechanisms for peaceful co-existence and were an example of the possibility of such co-existence. Moreover, members of the Jewish and Arab communities established chapters of "Consenso por una Paz Palestina Israeli" in Latin America – an initiative that seeks to mobilize the Arab and Jewish diasporas in Latin America to address the conflict through dialogue, and through creating learning opportunities within and between Arab and Jewish communities of Latin America to promote recognition of a common Abrahamic origin. A representative of this organization briefed the participants on the results of cooperation between the two diasporas in Latin America.
Recognizing the importance of the civil society and the academia in the promotion of the peaceful settlement of the conflict, the participants reviewed the concrete civil society activities and academic initiatives and events geared towards a better understanding of the origins and complexity of the Arab-Israeli and Israeli-Palestinian conflict among the general public and university students in Latin America. A number of important academic collaborations between Latin American, US and Palestinian universities and colleges were highlighted, that were aimed at promoting dialogue between the Jewish and Arab youth. Participants were unanimous in acknowledging the importance of education in order to change the situation in the Israeli-Palestinian conflict, and expressed regret that far too often Palestinians were portrayed as militants that threaten the State of Israel, while no context was given in regard to the decades-long occupation and violations of the human rights of the Palestinian people.
The Permanent Observer of the State of Palestine to the United Nations expressed his appreciation for the dedicated role Latin American countries in general, and Ecuador in particular, played in promoting the two-State solution to the Israeli-Palestinian conflict. He was impressed by the level of awareness and engagement of the Latin American civil society and academia in advancing the cause of the Palestinian people. He said more was needed to be done for these joint efforts to be effective in persuading Israel to discontinue its illegal policies and the occupation as a whole, and referred to the European Union trade and funding guidelines, and to the recent steps taken by some Western banks and pension funds, all in response to Israeli illegal settlement activity.
In the closing session, the representative of Ecuador said that the hosting of that important Meeting in the capital Quito was an evidence of the commitment of the Government of Ecuador to a just and lasting solution of the question of Palestine. Ecuador was in the forefront of solidarity with the Palestinian people by supporting their cause of creating an independent State within the 1967 borders and with East Jerusalem as its capital at the United Nations, in the Non-Aligned Movement, and by supporting the mandate and work of the UN Committee on the Exercise of the Inalienable Rights of the Palestinian People. In the future, Ecuador intended to continue such support and suggested hosting a meeting of young Israelis and Palestinians with the aim of promoting their mutual understanding and their knowledge of the co-existence of the Arab and Jewish diasporas in Latin America.
The Ambassador of the State of Palestine to Ecuador reminded that the President of the State of Palestine Abbas, with the support of the Palestinian people, was resolute not to compromise on a single square meter of the Palestinian land. There must be an independent Palestinian State created on the basis of the 1967 borders, with East Jerusalem as its capital, and the adoption of the UN General Assembly Resolution 67/19 was the first step in that direction, he said. The current status quo was unacceptable, he stressed, and recalled the UN General Assembly Resolution 194 and the Arab Peace Initiative as some of the existing tools to advance the Palestinian cause. He called on the Government of Israel to live up to the principles of a democratic and non-discriminating State that Israel claims to be. Peace was justice, he said, not the settlements, the wall, the violation of the human rights of the Palestinian people. In conclusion, he thanked the Government and the people of Ecuador for their hospitality and unwavering support of the Palestinian people, and expressed the hope for further fruitful cooperation between the two States.
The Chairman of the Committee expressed his gratitude to the representative of Ecuador for outlining concrete commitments and offering personal support in the organization of regional initiatives in solidarity with the Palestinian people in Latin America. The Chairman also noted Ecuador's support for the convening by the Committee, later in 2014, of an international meeting of parliamentarians in New York in support of the Palestinian people. Summing up the results of discussions during the Meeting, the Chairman welcomed the multitude of ideas put forward by the participants for the 2014 International Year of Solidarity with the Palestinian People. He also reiterated his appreciation of the concrete actions such as the measures taken by some European banks severing their ties with companies having business activity in the Israeli settlements in the West Bank, or measures requiring to label Israeli goods produced in settlements as such. The Chairman concluded by calling for the cooperation and support of the intergovernmental, non-governmental and academic entities present at the Meeting to help end the Israeli-Palestinian conflict.
Note: This Summary attempts to provide an overall picture of the deliberations of the Meeting. A detailed report summarizing each statement and presentation will be published by the Division for Palestinian Rights in due course.


The signing of the "17-Article Agreement" on the peaceful liberation of <?xml:namespace prefix = st1 ns = "urn:schemas-microsoft-com:office:smarttags" />Tibet in Beijing 50 years ago turned a new page in the history of Tibet, according to a Xinhua report from LHASA, capital of China's Tibet Autonomous Region.
Legqog, Chairman of the Tibet Autonomous Regional Government, said that thanks to the earth-shaking progress made in the past 50 years, Tibetans have walked out of the old, dark, backward and closed life and entered into a new, bright, modern, prosperous and open life.
The old Tibet, with its feudal serfdom, was a very dark decayed society. The three major estate-holders (Kasha, nobles and upper-ranking Lamas), who accounted for less than 5% of the population in Tibet, owned serfs and slaves who made up more than 95% of the population.
Moreover, as productivity in old Tibet was very low and economy very stagnant, the broad masses of serfs did not have enough to eat and wear. The old Tibet far outstripped medieval Europe of cruelty and gloom.
The peaceful liberation of Tibet in 1951 is considered a turning point in the history of Tibet. It reflected the common aspirations of Tibetan people and other ethnic peoples in China smashed the imperialist conspiracy to split China and laid a solid foundation for the unity of the Chinese nation.
The democratic reform that came 8 years later overthrew the dictatorship by the upper-class lamas and nobles who ruled Tibet with theocracy and feudal serfdom. The broad masses of former serfs became masters of their own destinies.
The Tibet Autonomous Region was established in 1965 when the first regional people's congress was convened.
So far, the Tibet Autonomous Region has made more than 150 local laws and regulations, which involve all aspects of life in Tibet.
In the National People's Congress, the highest legislature of China, 19 deputies are from Tibet. Tibetans and other ethnic peoples account for 90% of deputies in people's congresses at all levels in Tibet. They also make up 74.9% of cadres in the region.
The Central Government of China has invested or allocated more than 50 billion yuan to Tibet in the past 50 years. By 2000, Tibet's gross domestic product had reached 11.74 billion yuan, a 30-fold increase over that of 1951.
About 95% of farmers and herdsmen in Tibet have adequate food and clothing and are headed towards greater prosperity.
In old Tibet, there were no modern industries, but today; Tibet's industrial output value has risen to 1.83 billion yuan, up 11 times from that of 1959.
There was only one small hydropower station that generated electricity for the privileged few in Tibet before the peaceful liberation. Now Tibet is blessed with 401 power stations, which are capable of generating 660 million kwh annually.
Fifty years ago, there were no highways in Tibet. The car given to the 14th Dalai Lama by Britain could only run on the two-km earth road from the Potala Palace to Norbu Lingka, known as Dalai Lama's summer palace. Now, Tibet has built a highway network centered on Lhasa. The total length of it is about 25,300 km. Highways will extend to all counties in Tibet in 5 years, while the construction of the Golmud-Lhasa railway, the highest one in the world, will start in July this year.
Mobile phones, Internet, wireless pagers and postal services are common means of communication among ordinary Tibetans at present day. Tibet has begun a new era wherein satellites and fibre-optic cables form an efficient network of communication.
Tibet has witnessed great progress as well in education, culture and other social undertakings in the past 50 years. Among the school-age children in Tibet, 85% of them attend school, while the illiteracy rate among young people has dropped from 97% in old Tibet to 39% today. Press and publication developed quickly. Traditional culture is well protected. Medical care and public health network has been established. The average life span of Tibetans has risen from 36 years in 1950 to today's 67.


text:
Сердце-обличитель — британский фильм ужасов 1960 года режиссёра Эрнеста Морриса, спродюсированный Danzigers. Сценарий Брайана Клеменса и Элдона Ховарда представляет собой вольную адаптацию одноимённого рассказа Эдгара Аллана По. Фильм был выпущен в Англии в декабре 1960 года и в США в феврале 1962 года под названием «Скрытая комната 1000 ужасов».

Сюжет
Эдгар Марш, застенчивый библиотекарь, одержимый эротикой, влюбляется в свою соседку Бетти Клэр, когда видит, как она раздевается в своей спальне. Он приглашает её на ужин и, хотя ей явно не нравится то внимание, которое он ей уделяет, осыпает её драгоценностями и фантазирует об их совместном будущем. Сложности возникают, когда он знакомит её со своим другом Карлом Лумисом, которого Бетти находит гораздо более привлекательным. Увидев Карла и Бетти вместе в её спальне, Эдгар забивает Карла до смерти кочергой и хоронит его под половицами в своей комнате с фортепиано. Его непреодолимая вина заставляет его поверить, что тиканье метронома и непрекращающееся капание воды из крана на самом деле являются звуками всё ещё бьющегося сердца его жертвы.

Состав
  . . . . . Эдгар Марш
 Эдриэнн Корри . . . . . Бетти Клэр
 Дермот Уолш . . . . . Карл Лумис

Производство
В то время, когда фильм был снят, типичный бюджет художественного фильма Danzigers составлял 15 000 фунтов стерлингов. Этот фильм обошёлся немного дороже из-за настройек съёмки и, в частности, необходимости съёмки в чёрно-белом режиме.

Критика
«Сердце-обличитель» был выбран историками кино Стивом Чибналлом и Брайаном Макфарлейном как один из 15 наиболее достойных британских фильмов категории B, снятых в период между Второй мировой войной и 1970 годом. Они отмечают, что во время выпуска он также получил восторженные отзывы от The Monthly Film Bulletin и Kinematograph Weekly.

Примечания

Ссылки

Фильмы ужасов Великобритании
Независимые фильмы Великобритании
Чёрно-белые фильмы Великобритании
Фильмы ужасов 1960 года

redpajama_set_name: RedPajamaWikipedia


So is everyone else. Whether it's the killer school district, walkability, or central location that makes your target neighborhood a top pick, odds are homes for sale in hot markets are hard to come by.
If you want to call your dream 'hood home, you're going to need to buy smart. Luckily, you're not in this alone. We know what buying in a hot market (also called a seller's market) takes and how to get there. When the time comes to make an offer, you'll want the leg up.
With that in mind, if you have your heart set on buying in one of these areas, starting your house hunt early and having patience means that time will be on your side. And when the moment comes, you'll need to act quickly.
Set yourself up for success by putting your dream 'hood(s) in your Open Listings feed. That way, you'll know the minute a house that matches your needs hits the market.
If you're really interested in the house, get as much info as you can beforehand: ask for property reports & disclosures, and find out when offers are due. Open Listings' Buyer Experience team can reach out to the seller's agent on your behalf.
Even after you've seen the home, speed is still the name of the game. Double check with the selling agent when he or she intends to present any offers on the home so that you can be sure to submit yours on time.
Most offers include contingencies -- things like completing inspections and receiving a mortgage commitment -- that need to happen for the transaction to move forward.
When looking at offers, sellers tend to see contingencies as potential opportunities for the deal to fall apart. As a result, they're more likely to choose an offer that's relatively "clean" or reduces their risk of potential hang-ups.
In a competitive market, you'll see people either removing or reducing their contingency periods to make their offer more competitive.
Aside from keeping your contingencies in check, there is one other obvious component of the offer that will help set you apart from the crowd -- the offer price.
We've found that Open Listings buyers who submit offer letters are 2x as likely to get the house.
Looking to buy a home in a hot market? Open Listings is designed to give you an edge. Plus, save thousands when you buy with us.


text:
Rock fan jailed after driving neighbours mad by blasting out hits by PINK FLOYD
The home where noisy neighbour Paul Foster kept belting out Pink Floyd tracks
A rock fan who drove his neighbours round the bend by constantly blasting out hits by PINK FLOYD in the middle of the night has been jailed for 28 days.
Paul Foster, 51, repeatedly played tracks by the British 70's prog rock band at full volume making residents lives a misery.
Fed-up neighbours said Foster would often leave his radio on all night pumping out albums such as 'Dark Side of The Moon', 'The Wall' and 'Wish You Were Here'.
Stoke-on-Trent County Court heard how one family even moved out of the area because they couldn't put up with the loud music – which also included late night love ballads.
On TuesdayFoster, from Chesterton, Stoke-on-Trent, Staffs., was caged for breaching an injunction from playing loud music for the FIFTH time.
Speaking after the hearing, Caroline Baggaley, Head of Aspire – the housing association where Foster lived, said: "We are pleased with the sentencing, as we do not tolerate antisocial behaviour – in particular noise nuisance.
"The vast majority of our customers have a quiet enjoyment of their homes and neighbourhoods and Aspire wants to ensure that everyone maintains this standard of conduct."
One neighbour, who did not wish to be named, said after the case: "Its been a nightmare. I like Pink Floyd as much as the next man but not when it's being played ten times a day until 4am.
"He also seemed to like his late night love ballads – I've lost track of the times I've heard Barry White and Marvin Gaye coming from the house.
"But it was mainly Pink Floyd, and I think whenever I hear their songs again I'll be climbing the walls.
"We just hope this teaches him a lessons and we can get a good nights sleep from now on."
Another neighbour, added: "It's been going on for years. He has probably lived here for about 20 years.
"The people who used to live next door to him moved out because they couldn't stand the noise anymore. It can go on all night.
"Most of the time he keeps himself to himself. He will say hello – but I think he likes a drink and he has been in trouble in the past."
Foster was first hauled before the courts in September last year but then breached an 'undertaking to his future conduct' agreement on October 4 and December 1 last year.
He was sentenced to 21 days in jail suspended for one year on January 17 and also served with an injunction banning him from causing nuisance noise.
He breached the injunction on February 22 and was jailed for 63 days on March 20 when he admitted further breaches.
Foster then breached the injunction again on May 30 despite spending time at at HMP Dovegate prison, in Staffordshire.
Stunning home the Queen gave to Sir Christopher Wren because she owed him money goes on sale for £4.25 million.
BGT judge David Walliams voted Britain's best-loved celebrity dad
BGT judge David Walliams voted Britain's best-loved celebrity dad


text:
Bailando con las estrellas 2018 en La 1, es la primera edición del programa español Bailando con las estrellas, basado en el formato británico Strictly Come Dancing. La cadena comunicó en febrero de 2018 que había dado vía libre a este proyecto, producido por Gestmusic Endemol.

En abril de 2018, Roberto Leal y Rocío Muñoz fueron confirmados oficialmente como los presentadores del programa. El 24 de julio, en la Gran Final, se proclamó a David Bustamante y Yana Oliana como los ganadores de esta edición.

Parejas
El 23 de abril, Gestmusic empezó a confirmar la lista de concursantes de esta primera edición. La primera celebrity en ser anunciada fue la nadadora sincronizada Gemma Mengual. El resto de concursantes se fueron anunciando periódicamente conforme se fue acercando la fecha del estreno. El 9 de mayo, se confirmó oficialmente al elenco y a los bailarines profesionales en la rueda de prensa de presentación del programa.

Presentadores y jueces

Roberto Leal y Rocío Muñoz Morales fueron los presentadores, mientras que Moira Chapman (coreógrafa y directora de producción), Joaquín Cortés (bailarín y coreógrafo) e Isabel Pérez (bailarina y coreógrafa) fueron nombrados jueces del programa. Además, el programa contó con una supervisora de coreografías, ya que los autores de las coreografías son los mismos bailarines, Vicky Gómez fue la encargada de adaptar las coreografías a la televisión y de montar los números grupales. Y además, la juez Isabel Pérez comprobó que las coreografías se adaptan al baile de salón y que el nivel entre todas ellas sea equilibrado.

Resultados del jurado

Números rojos Indica el resultado más bajo por cada semana
Números verdes Indica el resultado más alto por cada semana
 la pareja eliminada de la semana
 la pareja fue la última salvada

Promedio
Esta tabla solo cuenta con los bailes calificados en una escala de 30 puntos (las puntuaciones de los jueces invitados están excluidas).

Puntuaciones por baile
Las mejores y peores actuaciones en cada baile según la escala de 30 puntos de los jueces (las puntuaciones de los jueces invitados están excluidas).

Puntuaciones por pareja
Los puntajes se basan en la escala tradicional de 30 puntos (los puntajes de los jueces invitados están excluidos).

Actuaciones semanales
Las puntuaciones de los jueces en las tablas (en paréntesis) se encuentran en el siguiente orden: Moira Chapman, Joaquín Cortés, Isabel Pérez.

Semana 1: Primeros bailes

Al ser la primera gala, no hay expulsión y los resultados se sumarán a los de la segunda semana para determinar el expulsado. Por eso, el programa hizo públicos los resultados.

 Actuación: Presentadores (Roberto Leal & Rocío Muñoz) - Salsa («Échame la culpa»—Luis Fonsi y Demi Lovato)

Orden de aparición

Semana 2

 Artista invitado: «Lo malo»—Aitana y Ana Guerra

Orden de aparición

Semana 3

 Artista invitado: «La cintura»—Álvaro Soler

Orden de aparición

Semana 4

 Bailarines invitados: Los Vivancos — Espectáculo "Nacidos para bailar"

Orden de aparición

Semana 5

 Actuación: Bailarines profesionales - «When love takes over»—David Guetta feat. Kelly Rowland
 Artistas invitados: «¿Quién es ese?»—Carlos Baute y Maite Perroni

Orden de aparición

Semana 6: Especial Cine

 Actuación: Bailarines profesionales - «Sparkling diamonds»—Moulin Rouge
 Bailarines invitados: Roberto Leal y Rocío Muñoz Morales — Quickstep ("Supercalifragilisticoespialidoso"—Mary Poppins)

Orden de aparición

Semana 7

 Artistas invitados: «Él no soy yo»—Blas Cantó y «Nacidos para creer»—Amaia Montero

Orden de aparición

Semana 8

 Artistas invitados: «Por una vez más»—Roi Méndez y «Sin pijama»—Becky G

Orden de aparición

Semana 9
 Actuación: Bailarines profesionales - «Want U Back»—Cher Lloyd
 Artistas invitados: «Miénteme al oído»—Luz Casal y Musical Michael Jackson

Orden de aparición

Semana 10: Semifinal
 Actuación: Bailarines profesionales  - «Footloose»—Kenny Loggins
 Artistas invitados: «Te lo mereces» - Merche
 Actuación especial:  Gloria Ramos - Merengue («Suavemente»—Elvis Crespo)

Orden de aparición

Semana 11: Final
 Actuación: Bailarines profesionales y los concursantes—«I Wanna Dance with Somebody (Who Loves Me)»—Whitney Houston
 Artistas invitados: «Hay algo en mí»—Miriam Rodríguez

Orden de aparición

Tabla de bailes

 Baile mejor valorado de la gala
 Baile peor valorado de la gala

 Semana 1: Chachachá, Foxtrot, Jive, Tango, Pasodoble, Vals o Vals vienés
 Semana 2: Un baile no aprendido
 Semana 3: Un baile no aprendido (Se introduce: Salsa, Samba, Urban y Quickstep)
 Semana 4: Un baile no aprendido (Se introduce: Contemporáneo)
 Semana 5: Un baile no aprendido (Se introduce: Rumba)
 Semana 6: Especial Cine Un baile no aprendido
 Semana 7: Un baile no aprendido
 Semana 8: Un bailes no aprendido
 Semana 9: Dos bailes no aprendidos
 Semana 10: Semifinal Dos bailes no aprendidos
 Semana 11: Final Tres bailes (Se introduce: Free-style)

Audiencia

 Líder de la noche.
 Récord de audiencia.
 Media de audiencia del programa

Referencias

Bailando con las estrellas


Thanks for meeting with us, Rick! So you've been with Charlotte magazine since 1995. Tell us about your journey to publisher. At that point we were more or less a new magazine. We had just purchased the name Charlotte magazine and that was pretty much it – we started over from scratch. Essentially, I was the guy that did the stuff that needed to be done. I went from editorial assistant to assistant editor to associate editor all before first issue. I was on the editorial side for 18 years—15 as editor—before moving to publisher in January 2013.
What is your long term vision for the magazine? We will continue to find ways to grow and connect with our audience, and continue to do what we do, but do it even better. It's important for us to have a direct relationship with our audience and cultivate it through storytelling. From an advertising perspective, we're selling exclusive access to our audience, and it's exciting because some of those opportunities don't even exist yet. Just think about what we're doing now that didn't even exist five years ago. The important thing for us to always keep in mind is why we're doing it in the first place.
How have things changed given the technology and social media aspect of publishing? We're doing a whole lot more, and we're doing it faster. Even three years ago all you could really do was buy an ad. Now you can sponsor an event, sponsor our newsletter, advertise on our website, create a social campaign, etc. There are a lot of different ways to connect with people. All are content-based but each has to be rooted in connecting with our audience so we ensure we're serving the reader.
We were an early adopter of Twitter. Events have become popular. Our Best of the Best (BOB Awards) event has grown by 100 people each year over the past several years – 750 came last year. The Charlottean of the Year Award (which debuted in December 2014) came out of editorial. We did it because we saw a need to recognize the people that are making our city better, and we thought the city magazine should be the one to do it. We solicited nominations from the community and from community leaders then our editorial board made the final decision.
Tell us a little more about earned media opportunities available? I'll be honest, when I was editor, a PR person said to me once, "You're the hardest publication in the state to get into." I took that as compliment. We work so hard to service our readers. We're a monthly so there's not a lot of space, and it's not all that often a press release finds its way in our magazine. However, for example, if we're doing a story on hamburgers and we receive a press release about a new restaurant specializing in burgers, it makes us aware and that restaurant may get included.
Securing placement in our magazine really takes an understanding of what we're trying to do, who we're trying to reach and the exact type of story we're looking for. It's helpful if someone external provides a different angle to an existing trend we're covering. That's because we really try to do stories that nobody else is doing and we don't typically cover something that's already been covered.
Understanding you're a long lead magazine, how far out are you planning? Our April issue is going to print now and it was fully assigned 3-4 weeks ago. A lot of our features and longer pieces are over four months out. Our covers, at least the concepts, have been decided over a year in advance.
What about your blogs? Is there an opportunity to cover things you wouldn't in print? Do they provide an opportunity to cover stories faster? Yes; our blogs are becoming more of the place where we can get out in front of things and be the first with news. Our bloggers get direct pitches. They are looking for content more often, but we make sure they're quality. We try to take the time to interview folks and come up with interesting and unique angles. Those blog posts are the ones that get the most traffic.
Do you feel like you have competition? That depends on if you ask account reps or editorial staff! When you think about it, we're really just competing for people's time. We do things that no one else is doing, or in a very different manner, so we're not worried as much about what our competition might do. We just do what we do.
Your mantra is connecting with readers so if you had one thing to tell them what would it be? We're trying to create a great magazine experience. You will find things in our pages you won't find anywhere else – online, social and print. Our stories are as good as or better than anything you'll read in the country. That's why they get picked up and shared nationally through publications like the New York Times and BuzzFeed.


text:
Most memorable monsoon movie scenes of Bollywood!
25 Aug 2019 03:00 PM
The monsoons are here in full throttle, and it got us reminiscing all the things Indians love to do in the rains! For once, definitely get drenched in the billowing showers, apart from savoring our favorite deep-fried pakkoras paired with piping hot chai – now, did that get your mouth watering! Most importantly, we all love staying indoors, enjoying the pitter-patter on the window sill, while watching Bollywood's best and biggest stars on our television sets. Sony MAX acknowledges India's deewangi for rains and to celebrate 20th anniversary of the channel, we have listed down the best ever rain-scenes of Bollywood movies:
Lagaan
A film with ten thousand actors, Lagaan is definitely an unforgettable movie in the history of Indian cinema. Set in the British Raj, we absolutely went hysterical during the climax of the movie, and no one can ever forget the mesmerizing rain scene that follows the magnificent win by the rookie Indian team against the skilled British army. As we see the villagers dance in the rain in the glory of their victory, the British are running for cover, symbolizing their defeat. It ends with the protagonist's mother looking at the sky with a content heart.
Wake-up Sid
The film showcased a more beautiful side of Mumbai, in the rains. The concluding scene of the film where Aisha confesses her love for Sid and the city through an article in her Magazine is by far the best one in the movie. The two meet near the sea while the city is lashed by rains and their hug is something that is etched forever in our memories.
Nargis - Sunil Dutt'scult classic and an iconic movie, Mother India features the most exhilarating Holi scene to be ever seen on the silver screen. The most memorable scene is one where the village gets flooded and the crops are washed away due to the cloudburst. We see the protagonist with her three children, without her husband, struggling through the bitter realities of life. Since then for generations, it has become the embodiment of the spirit of Mother India.
KuchKuchHota Hai
What can be more romantic than Shah Rukh Khan cajoling Kajol under a gazebo amidst a light monsoon shower? "Aurpaasaao, aurpaasaao" he said and as Kajol inched towards SRK, every time this scene plays, bet almost all of us go weak in our knees! You could feel the love between the on-screen couple as you clutched on to your couch. That was sheer magic in KuchKuchHota Hai. In fact, that was a priceless moment!
Raja Hindustaani
Not even the downpour could wash out the serious attraction between Karisma Kapoor and Aamir Khan in Raja Hindustani. A jittery Karisma shivered in the cold rain and Aamir held her in his arms. The following kiss generated enough steam to leave everyone misty. The scene was a symbol of unadulterated passion. The rain washed off all inhibitions between two lovers.
Dhoom2
There is nothing quite better than a little competition between two people feeling the heat of attraction. Hrithik Roshan and Aishwarya Rai Bachchan sweated it out in the rain on a basketball court. And with each hoop scored and splash of water the laws of attraction got stronger. By the time the game was over, Hrithik and Ash were high on love.
One of the most talked about super hits of 2013, Mohit Suri's Aashiqui 2 featured Aditya Roy Kapur and Shraddha Kapoor as an ill-fated couple. The iconic rain scenes between Shraddha Kapoor and Aditya Roy Kapur when they put a jacket on each other to express their love is still remembered by all.
Hum Tum
Rani Mukerji and Saif Ali Khan keep bumping into each other in this epic romantic comedy where they first hate each other but end up falling in love. The rain scene in this film is epic and should not be missed!
DilTohPagal Hai
Rain plays such an important role in this romantic drama, that there is even a song dedicated to it! Learn the steps of ChakDhoomDhoom with SRK and Madhuri Dixit and then go out on your terrace and have your very own rain dance party!
Life in a metro
This is Anurag Basu's ode to Mumbai. Life In A... Metro narrates the short stories of various characters who call Mumbai home, using the monsoon as the one constant element that ties these tales together. Basu recognizes Mumbai's relationship with the season and gives it a new voice in the movie; topping it off with the hit song, Alvida.
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8 reviews of Kidds Beach Accommodation.
We arrived Sunday night and found most Restaurants closed which was a bummer.
This was our first visit to this little seaside village, and it won't be our last. Kidds Beach is a hidden gem with pristine beach to the one side and rocky coastline to the other. It feels like you're miles from everywhere, but East London is just minutes down the road. Perfect place for a family seaside holiday.
Very friendly environment, beatiful beach, kids enjoyed it.


text:
Home News Battery Tech
Stellantis Hints At More More Battery Plants In North America By 2030
The company might need two more battery gigafactories on top of the two already announced.
Oct 20, 2022 at 8:23am ET
By: Mark Kane
Stellantis potentially will build one or two more lithium-ion EV battery plants in North America by 2030, on top of two already contracted.
The company's North American COO Mark Stewart said at a Reuters Events auto conference in Detroit that a total of four gigafactories might be needed by the end of this decade to support mass electrification. That's in addition to a few plants in Europe (three plants - in France, Germany and Italy under the Automotive Cells Company JV).
Let's recall that Stellantis currently has two projects underway:
Canada: a 45+ GWh/year battery joint venture with LG Energy Solution
US (Indiana): a 23 GWh/year battery joint venture with Samsung SDI
The plant in Canada is expected to start production in the first quarter of 2024, while the plant in Indiana will start production in the first half of 2025.
The third North American battery gigafactory is expected to be needed in 2026/2027. This topic is currently being discussed and an official announcement will be made by Q2 2023, while the fourth plant is a possibility (by 2030).
"By quarter two, quarter three of '26, if the market continues on the path that it's on, we'll need the third plant online by late '26, early '27. We are already in discussions for plant No. 3 and possibly plant No. 4. We will need four plants by 2030."
It's not decided where the two additional plants would be built (US, Canada or Mexico) or who will be the partner.
As we can see, manufacturers are now preparing for even higher battery-electric car output than initially anticipated. At the Stellantis EV Day 2021, the company planned 3 plants globally by 2025 and 5+ plants by 2030. Now it seems that we are talking about 6-7 with an option for even more.
Part of the reason why Stellantis might be interested in more battery plants in North America is changes in the federal tax credit incentives, which promoted locally produced BEVs, with locally produced batteries.
US: Jeep Wrangler 4xe Surged To Over 13,000 Sales In Q3 2022
Stellantis Exec: The Car Market Might Collapse If EVs Don't Get Cheaper
Battery Tech Manufacturing / Production


text:
package com.google.android.agera.net;

import android.support.annotation.NonNull;
import java.util.Arrays;
import java.util.Map;

/**
 * An object representing a request to the http functions.
 */
public final class HttpRequest {
  @NonNull
  final String method;
  @NonNull
  final String url;
  @NonNull
  final byte[] body;
  @NonNull
  final Map<String, String> header;
  final boolean useCaches;
  final boolean followRedirects;
  final int connectTimeoutMs;
  final int readTimeoutMs;

  HttpRequest(@NonNull final String method, @NonNull final String url,
      @NonNull final byte[] body, @NonNull final Map<String, String> header,
      final boolean useCaches, final boolean followRedirects, final int connectTimeoutMs,
      final int readTimeoutMs) {
    this.method = method;
    this.url = url;
    this.body = body;
    this.header = header;
    this.useCaches = useCaches;
    this.followRedirects = followRedirects;
    this.connectTimeoutMs = connectTimeoutMs;
    this.readTimeoutMs = readTimeoutMs;
  }

  @Override
  public String toString() {
    return "HttpRequest{" +
        "method='" + method + '\'' +
        ", url='" + url + '\'' +
        ", body=" + Arrays.toString(body) +
        ", header=" + header +
        '}';
  }

  @Override
  public boolean equals(final Object o) {
    if (this == o) { return true; }
    if (o == null || getClass() != o.getClass()) { return false; }

    final HttpRequest that = (HttpRequest) o;

    if (useCaches != that.useCaches) { return false; }
    if (followRedirects != that.followRedirects) { return false; }
    if (connectTimeoutMs != that.connectTimeoutMs) { return false; }
    if (readTimeoutMs != that.readTimeoutMs) { return false; }
    if (!method.equals(that.method)) { return false; }
    if (!url.equals(that.url)) { return false; }
    if (!Arrays.equals(body, that.body)) { return false; }
    if (!header.equals(that.header)) { return false; }

    return true;
  }

  @Override
  public int hashCode() {
    int result = method.hashCode();
    result = 31 * result + url.hashCode();
    result = 31 * result + Arrays.hashCode(body);
    result = 31 * result + header.hashCode();
    result = 31 * result + (useCaches ? 1 : 0);
    result = 31 * result + (followRedirects ? 1 : 0);
    result = 31 * result + connectTimeoutMs;
    result = 31 * result + readTimeoutMs;
    return result;
  }
}

redpajama_set_name: RedPajamaGithub


The type of saturated fats we eat can affect our risk of a heart attack, according to a study published in the International Journal of Cardiology. People whose diets contain relatively little palmitic and stearic acid – saturated fats composed of 16 or more carbon atoms (longer-chain saturated fats) that are typically found in meats – and eat plant-based proteins instead have decreased chances of myocardial infarction. Moreover, individuals who eat more saturated fats with 14 or fewer carbon atoms (shorter-chain saturated fats) that are typically found in dairy products have lower risk of myocardial infarction.
"Our analysis of the diets of large groups of individuals in two countries over time shows that the type of saturated fats we consume could affect our cardiovascular heath," explained lead investigator Ivonne Sluijs, PhD, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
The study investigated whether saturated fats with chains varying in length from 4 to 18 carbon atoms are associated with the risk of developing a myocardial infarction. Data from approximately 75,000 people in the UK and Denmark were analyzed. Of these two groups, nearly 3,500 people experienced myocardial infarction in the period between the study's initial outreach and follow-up 13 years later (in Denmark) and 18 years later (in the UK).
"We found that eating relatively little of the longer chained saturated fatty acids and consuming plant-based proteins instead was associated with a lowered risk. Substitution of those saturated fats with other energy sources such as carbohydrates did not affect the risk to develop myocardial infarction," said Dr. Sluijs. Although diets vary by nationality and other factors, the most frequently consumed saturated fat is palmitic acid, with 16 carbon atoms, followed by stearic acid, with 18 carbon atoms, both of which are found in meat products. Consumption of saturated fats that have shorter carbon atom chains and are present in dairy products is less prevalent.
"Our study only allowed us to draw conclusions on the level of associations between saturated fatty acids and the development of myocardial infarction. We do not know whether those fatty acids are actually the cause of differences between the occurrences of myocardial infarction we observed. To further explore this, we need experiments in which the consumption of saturated fatty acids is more controlled and, for instance, compared with consumption of unsaturated fatty acids," she noted.
"The study is applaudable for its large size, prospective cohort study design, and detailed assessment of diet and lifestyle factors. In addition, it is among the few studies that specifically examined individual saturated fatty acids in relation to coronary heart disease risk and compared with different macronutrients," commented Jun Li, MD, PhD, and Qi Sun, MD, ScD, both at the Harvard T.H. Chan School of Public Health, Boston, MA, USA, in an accompanying editorial. They also noted a few limitations of the study and thus called for cautious interpretation of the overall null results for the primary saturated fatty acids.
The article is "Consumption of individual saturated fatty acids and the risk of myocardial infarction in a UK and a Danish cohort," Jaike Praagman, Linda E.T. Vissers, Angela A. Mulligan, Anne Sofie Dam Laursen, Joline W.J. Beulens, Yvonne T. van der Schouw, Nicholas J.Wareham, Camilla Plambeck Hansen, Kay-Tee Khaw, Marianne Uhre Jakobsen, and Ivonne Sluijs (https://doi.org/10.1016/j.ijcard.2018.10.064). The editorial is "Consumption of saturated fatty acids and coronary heart disease risk," by Jun Li and Qi Sun (https://doi.org/10.1016/j.ijcard.2019.01.022). They will appear in the International Journal of Cardiology, volume 279 (April 2019) published by Elsevier.
Yvonne T. van der Schouw and Ivonne Sluijs report receiving a restricted Research Grant from Unilever Research and Development Vlaardingen, the Netherlands, which funded the salary of Jaike Praagman. Unilever Research and Development had no role in the design and conduct of the study, and the writing of the paper.
Full text of the article and editorial are available to credentialed journalists upon request and are also openly available online. Contact Jonathan Davis, Communications Officer, Elsevier, at newsroom@elsevier.com to obtain copies. Journalists wishing to schedule interviews with the study's authors should contact the Utrecht University press office at +31 88 75 55000 or press@umcutrecht.nl. To reach the editorial's authors for comment contact Jun Li at junli@hsph.harvard.edu.


text:
Ву́лиця Бегоу́лєва — одна з вулиць міста Шепетівка Хмельницької області, Україна.

Опис
Вулиця вузька. Починається від вулиці Залізничної, проходить на південь і впирається у вулицю Першотравневу.

Історія
Вулиця спочатку називалась Зеленою. На початку 1950-их років минулого століття її почали заселяти. Проходила уздовж безіменного струмка, де находився гай з верб, тонкостовбурних тополь, незвичних осокорів. 1969 року, коли помер місцевий Герой Радянського Союзу Б. П. Бегоулєв, вулицю назвали його ім'ям.

Походження назви
Вулиця названа на честь відомого лікаря-військовика, Героя Радянського Союзу, Бегоулєва Бориса Петровича.

Об'єкти

Галерея

Посилання
 Біографія Бегоулєва

Вулиці Шепетівки
Вулиці Шепетівки, названі на честь людей


text:
Levofloxacin Appears to Be Best Prophylactic for Pediatric ALL Patients
Memphis, TN—Initiation of chemotherapy for children with acute lymphoblastic leukemia (ALL) often leads to neutropenia, which, in turn, can increase risk of life-threatening infections that also can delay cancer treatment.
A study in Clinical Infectious Diseases notes that up to 4% of pediatric ALL patients die from treatment-related infections.
Now, however, St. Jude Children's Research Hospital researchers have identified an antibiotic that significantly reduces the odds of infections in those children, without also increasing antibiotic resistance.
"This research provides the first major evidence supporting targeted use of antibacterial prophylaxis for at-risk pediatric ALL patients, particularly use of the broad-spectrum antibiotic levofloxacin," explained lead author Joshua Wolf, MD, of the St. Jude Department of Infectious Diseases.
Preventive therapy with levofloxacin or other antibiotics reduced the odds of infection, including fevers and bloodstream infections, by 70% or more in ALL patients with neutropenia during induction therapy, study authors report.
Levofloxacin also reduced by 95% patients' odds of antibiotic-associated infection with Clostridium difficile; the hospital-acquired infection increases the risk of death in children seven-fold.
At the same time, levofloxacin allowed front-line antibiotics such as vancomycin and cefepime to be held back for use if patients develop infections during therapy.
"Prophylactic antibiotic therapy with levofloxacin is routine for at-risk adult ALL patients, but it has remained controversial in children," Wolf said. "Until this study, evidence supporting the safety and efficacy of prophylactic antibiotic therapy in children with ALL has been sparse."
The study, conducted from 2007 to 2016, included 344 St. Jude patients enrolled in the St. Jude Total XVI clinical trial for patients newly diagnosed with ALL.
The researchers used a change in hospital policy to compare approaches. Until July 2014, patients received prophylactic antibiotic therapy at the discretion of their physicians, but after that, hospital treatment guidelines changed to recommend prophylactic levofloxacin therapy during induction therapy for ALL patients who develop neutropenia expected to last at least 7 days.
The study compared 173 patients who received no preventive antibiotics; 69 patients treated prophylactically with levofloxacin; and 102 patients who received other prophylactic antibiotics, typically cefepime, ciprofloxacin, or vancomycin, alone or in combination.
While patients with neutropenia who received any prophylactic therapy were far less likely than those who did not to develop fever, documented or likely infections, or bloodstream infections, only the levofloxacin patients also showed reduction in C. difficile infections.
Read More On: NEWS
Study: Too Long a Duration Is a Type of Inappropriate Prescribing
Pharmacists, Prescribers Often Don't Follow STD Partner Therapy Guidelines
Polypharmacy Linked to Frailty in Older Patients


text:
New charter flight to connect Uzbekistan and China
BAKU, Azerbaijan, Dec.12
By Fakhri Vakilov - Trend:
A new charter flight will connect the capital of Uzbekistan, Tashkent and the Chinese tourist city of Chengdu until the start of 2020, as was announced by the head of Zhejiang Loong Airlines Co. Ltd Liu Yi at the presentation of the tourism potential of Uzbekistan in the Chinese city of Xi'an, Trend reports citing the Uzbek media.
Zhejiang Loong Airlines Co. Ltd will land first Airbus with guests from Chengdu, at the Tashkent airport on December 28. It is planned that the flight will be carried out twice a week.
"In recent years, as the Belt and Road Initiative has been promoted, new opportunities have opened up to expand cooperation between China and Uzbekistan. The new flights that our company introduces are the result of this dialogue. Currently the flight from Xi'an to Tashkent and vice versa is a charter one but we are discussing with the Uzbek side to make it regular,"said Liu Yi.
Since September 27 of this year, the Chinese carrier began operating flights from Xi'an to Tashkent and back on Airbus A320neo aircraft with a total capacity of 173 people. Next year Zhejiang Loong Airlines Co. Ltd also intends to launch a Hangzhou - Tashkent - Hangzhou flight.
As previously reported, Uzbekistan introduced a visa-free regime for Chinese tourists. From January 1, 2020, they will be able to come to Uzbekistan without visas for up to seven days.
Follow author on Twitter:@vakilovfaxri
Uzbekistan to build chemical plant to replace imports of hydrogen peroxide
Construction 19 January 20:39
China's Wuhan reports 17 new pneumonia cases
World Bank ready to participate in modernization of airports in Uzbekistan
Transport 18 January 18:21
Construction of gas pipeline ongoing in Uzbekistan's Kashkadarya region


# Scam scenarios: 30 minute scam - Nigerian for sure using the pretext of being in Long Island. This allowed me to play a little. I sent a fake Western Union number. Wasn't happy about that.
# Details: 30 minute scam - Nigerian for sure using the pretext of being in Long Island. This allowed me to play a little. I sent a fake Western Union number. Wasnt happy about that.


text:
Hurry Announces Two Song Single 'Frustrate You,' Out Now On Lame-O Records
Photo credit: Chris Sikich
Hurry Announce Two Song Single Frustrate You
Out Now via Lame-O Records
Philadelphia powerpop trio Hurry have just announced Frustrate You, a new two-song single out now on Lame-O Records. The new songs "Frustrate You" and "An Element Of Surprise" are streaming now via WXPN. The songs are available for purchase now via Bandcamp. Hurry will be playing with Happy Accidents at Everybody Hits in Philadelphia on Friday, May 10th.
Hear Frustrate You streaming now via WXPN:
https://thekey.xpn.org/2019/05/06/hurry-frustrate-you/
What was once a solo project for principal songwriter Matt Scottoline has evolved into Hurry, a power pop trio from Philadelphia, Pennsylvania composed of Scottoline, Rob DeCarolis (Univox), and Joe DeCarolis (Psychic Teens). The DeCarolises are cousins and they are both very talented. "As talented as Matt Scottoline?" Of course. Please don't attempt to pry the band apart with potentially hurtful questions.
Hurry's album Every Little Thought was released on February 23, 2018 on Lame-O Records. The album, written by Scottoline, is a light and dreamy plunge into life's crushingly relentless uncertainty and doubt. The album is more pop-driven than Hurry's previous efforts, focusing on catchy melodies, hooks, and harmonies influenced by Teenage Fanclub, Robyn Hitchcock, Yo La Tengo, and Guided By Voices. Of the new album, Scottoline — a natural salesman — says, "I tried even harder this time to make it good."
Hurry released it's previous album, Guided Meditation, on Lame-O Records in 2016. It was recorded at Noisy Little Critter with Mike Bardzik. The album was likely critically acclaimed, however Hurry does not place much value on things like "critical acclamation," nor do they place much value on "awards." In fact, Hurry did not even pay attention to 2017's Grammy winners. Ultimately, who knows if Guided Meditation won any (or all) of those awards.
Since Guided Meditation's release, Hurry has toured and played shows with Yuck, Nada Surf, and Tommy Keene, and have had their music featured on FXX's Man Seeking Woman. Scottoline, however, is not sure how important any of that information actually is. "I don't really think it is [important]," he says. Hm. You can judge for yourself.
Every Little Thought focuses on the general indecision of existence and how it can affect interpersonal relationships, as well as the frame of mind with which you approach day-to-day life. It is nice to listen to and it will make you smile.
Frustrate You track list:
1. Frustrate You
2. An Element Of Surprise
05/10 – Philadelphia, PA – Everybody Hits
w/ Happy Accidents (U.K.) and Gladie
05/19 – Philadelphia, PA – World Cafe Live
Rock The Cause benefit for Rock To The Future
07/12 – Philadelphia, PA – Kung Fu necktie
W/ the Sheila divine
Hurry Online:
The Pictish Trail shares new video 'The Handstand Crowd'
OKKULTOKRATI COMMENCE EU-UK SPRING TOUR; NEW MUSIC VIDEO FOR 'OCULAR VIOLENCE' REVEALED
DREAM NAILS release new single 'Kiss My Fist'
CULT OF LUNA RELEASE NEW SINGLE 'THE SILENT MAN'
Huddersfield trio Knuckle share new single 'Oh Mother' & video – Debut album 'Life Is Hard When You're Soft Inside' out 17th May


text:
Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo
Junichi Hachisuka, Hidemasa Furue, Masutaka Furue, Megumu Yoshimura
Itching is a common symptom in dermatologic diseases and causes restless scratching of the skin, which aggravates the condition. The mechanism of the itch sensation, however, is enigmatic. The present study included behavioral tests and electrophysiological recordings from rat dorsal root ganglion (DRG) neurons in vivo to analyze the response to pruritic stimuli induced by topical application of 5-hydroxytryptamine (5-HT) to the skin. Topically applied 5-HT to the rostral back evoked scratching, whereas application of the vehicle did not. Following subcutaneous injection of the opioid receptor antagonist naloxone, the number of scratches decreased, suggesting that the scratching was preferentially mediated by itch but not pain sensation. To elucidate the firing properties of DRG neurons in response to topically applied 5-HT, intracellular recordings were made from DRG neurons in vivo. None of the Aβ and Aδ neurons responded to 5-HT; in contrast, 25 of 91 C neurons (27%) exhibited repetitive firing in response to 5-HT, which could be classified into two firing patterns: one was a transient type, characterized by low firing frequency that decreased within 5 min; the other was a long-lasting type, having high firing frequency that continued increasing after 5 min. The time course of the firing pattern of long-lasting C neurons was comparable to the scratching behavior. Intriguingly, the long-lasting-type neurons had a significantly smaller fast afterhyperpolarization than that of the 5-HT-insensitive neurons. These observations suggest that the long-lasting-firing C neurons in rat DRG sensitive to 5-HT are responsible for conveying pruritic information to the spinal cord.
Journal of Neurophysiology
https://doi.org/10.1152/jn.00938.2009
10.1152/jn.00938.2009
Fingerprint Dive into the research topics of 'Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo'. Together they form a unique fingerprint.
Spinal Ganglia Medicine & Life Sciences
Serotonin Medicine & Life Sciences
Neurons Medicine & Life Sciences
Narcotic Antagonists Medicine & Life Sciences
Behavior Rating Scale Medicine & Life Sciences
Naloxone Medicine & Life Sciences
Subcutaneous Injections Medicine & Life Sciences
Hachisuka, J., Furue, H., Furue, M., & Yoshimura, M. (2010). Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo. Journal of Neurophysiology, 104(1), 271-279. https://doi.org/10.1152/jn.00938.2009
Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo. / Hachisuka, Junichi; Furue, Hidemasa; Furue, Masutaka; Yoshimura, Megumu.
In: Journal of Neurophysiology, Vol. 104, No. 1, 07.2010, p. 271-279.
Hachisuka, J, Furue, H, Furue, M & Yoshimura, M 2010, 'Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo', Journal of Neurophysiology, vol. 104, no. 1, pp. 271-279. https://doi.org/10.1152/jn.00938.2009
Hachisuka J, Furue H, Furue M, Yoshimura M. Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo. Journal of Neurophysiology. 2010 Jul;104(1):271-279. https://doi.org/10.1152/jn.00938.2009
Hachisuka, Junichi ; Furue, Hidemasa ; Furue, Masutaka ; Yoshimura, Megumu. / Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo. In: Journal of Neurophysiology. 2010 ; Vol. 104, No. 1. pp. 271-279.
@article{2e6110275a904339900a19cfb83922dc,
title = "Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo",
abstract = "Itching is a common symptom in dermatologic diseases and causes restless scratching of the skin, which aggravates the condition. The mechanism of the itch sensation, however, is enigmatic. The present study included behavioral tests and electrophysiological recordings from rat dorsal root ganglion (DRG) neurons in vivo to analyze the response to pruritic stimuli induced by topical application of 5-hydroxytryptamine (5-HT) to the skin. Topically applied 5-HT to the rostral back evoked scratching, whereas application of the vehicle did not. Following subcutaneous injection of the opioid receptor antagonist naloxone, the number of scratches decreased, suggesting that the scratching was preferentially mediated by itch but not pain sensation. To elucidate the firing properties of DRG neurons in response to topically applied 5-HT, intracellular recordings were made from DRG neurons in vivo. None of the Aβ and Aδ neurons responded to 5-HT; in contrast, 25 of 91 C neurons (27%) exhibited repetitive firing in response to 5-HT, which could be classified into two firing patterns: one was a transient type, characterized by low firing frequency that decreased within 5 min; the other was a long-lasting type, having high firing frequency that continued increasing after 5 min. The time course of the firing pattern of long-lasting C neurons was comparable to the scratching behavior. Intriguingly, the long-lasting-type neurons had a significantly smaller fast afterhyperpolarization than that of the 5-HT-insensitive neurons. These observations suggest that the long-lasting-firing C neurons in rat DRG sensitive to 5-HT are responsible for conveying pruritic information to the spinal cord.",
author = "Junichi Hachisuka and Hidemasa Furue and Masutaka Furue and Megumu Yoshimura",
doi = "10.1152/jn.00938.2009",
journal = "Journal of Neurophysiology",
T1 - Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo
AU - Hachisuka, Junichi
AU - Furue, Hidemasa
AU - Furue, Masutaka
AU - Yoshimura, Megumu
N2 - Itching is a common symptom in dermatologic diseases and causes restless scratching of the skin, which aggravates the condition. The mechanism of the itch sensation, however, is enigmatic. The present study included behavioral tests and electrophysiological recordings from rat dorsal root ganglion (DRG) neurons in vivo to analyze the response to pruritic stimuli induced by topical application of 5-hydroxytryptamine (5-HT) to the skin. Topically applied 5-HT to the rostral back evoked scratching, whereas application of the vehicle did not. Following subcutaneous injection of the opioid receptor antagonist naloxone, the number of scratches decreased, suggesting that the scratching was preferentially mediated by itch but not pain sensation. To elucidate the firing properties of DRG neurons in response to topically applied 5-HT, intracellular recordings were made from DRG neurons in vivo. None of the Aβ and Aδ neurons responded to 5-HT; in contrast, 25 of 91 C neurons (27%) exhibited repetitive firing in response to 5-HT, which could be classified into two firing patterns: one was a transient type, characterized by low firing frequency that decreased within 5 min; the other was a long-lasting type, having high firing frequency that continued increasing after 5 min. The time course of the firing pattern of long-lasting C neurons was comparable to the scratching behavior. Intriguingly, the long-lasting-type neurons had a significantly smaller fast afterhyperpolarization than that of the 5-HT-insensitive neurons. These observations suggest that the long-lasting-firing C neurons in rat DRG sensitive to 5-HT are responsible for conveying pruritic information to the spinal cord.
AB - Itching is a common symptom in dermatologic diseases and causes restless scratching of the skin, which aggravates the condition. The mechanism of the itch sensation, however, is enigmatic. The present study included behavioral tests and electrophysiological recordings from rat dorsal root ganglion (DRG) neurons in vivo to analyze the response to pruritic stimuli induced by topical application of 5-hydroxytryptamine (5-HT) to the skin. Topically applied 5-HT to the rostral back evoked scratching, whereas application of the vehicle did not. Following subcutaneous injection of the opioid receptor antagonist naloxone, the number of scratches decreased, suggesting that the scratching was preferentially mediated by itch but not pain sensation. To elucidate the firing properties of DRG neurons in response to topically applied 5-HT, intracellular recordings were made from DRG neurons in vivo. None of the Aβ and Aδ neurons responded to 5-HT; in contrast, 25 of 91 C neurons (27%) exhibited repetitive firing in response to 5-HT, which could be classified into two firing patterns: one was a transient type, characterized by low firing frequency that decreased within 5 min; the other was a long-lasting type, having high firing frequency that continued increasing after 5 min. The time course of the firing pattern of long-lasting C neurons was comparable to the scratching behavior. Intriguingly, the long-lasting-type neurons had a significantly smaller fast afterhyperpolarization than that of the 5-HT-insensitive neurons. These observations suggest that the long-lasting-firing C neurons in rat DRG sensitive to 5-HT are responsible for conveying pruritic information to the spinal cord.
U2 - 10.1152/jn.00938.2009
DO - 10.1152/jn.00938.2009
JO - Journal of Neurophysiology
JF - Journal of Neurophysiology


III Safety* Sentry Protective Headgear Made With High Density Polyethelene Material. Features 6-point Injection Molded Suspension With Nylon Straps. Designed With Accessory Slots For Additional.
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