In 1915 Opal was the most popular teenager in Oregon. She was a magnetic teacher blending science and faith in lectures to thousands of kids everyone thought she would be a great teacher or scientist. Instead, she became Oregon's most Controversial Author. See dozens of historical photos of her life. Website of the Opal Whiteley Memorial in Cottage Grove.
This is a true story of the bombing of a school called Ping Yang, near Marcola, Oregon. It was destroyed from an explosive mix of social, religious and racial prejudices. Here is a picture of the man reportedly behind the three bombings. He used racist imagery and people's fears of Chinese to fight against the school.
Read the forgotten story of the Japanese Colony of Mabel, Oregon (near Marcola). The 1920 US Census has almost 30 Japanese living where the BLM's Shotgun Creek Recreation Area is today. There also is a 1925 article that mentions an entire Japanese Colony and a 1916 list of men drafted for World War I.
This photo shows one of the world's largest railroad trestles, Much of the lumber they cut and milled was sent back to Japan by the Robert Dollar Steamship Company.
Here are several very rare photos and the story of Punjab Sikhs from India working in a Crawfordsville Oregon lumber mill. Sikhs and Hindus also worked in other local mills. This photo is from about 1909.
Also, read the story of a young Sikh who in was a student at Berkeley and worked in a lumber mill to earn money for his tuition and PhD. His immigration case later set a US legal precedent.
Read the fascinating story of how Cerro Gordo, Oregon got its name. There are at least seven other places around the US named for the Battle of Cerro Gordo. This was the deciding in the Mexican-American War of 1847. But, by the 1970s almost no one in Oregon remembered this often forgotten war. Our American Civil War just 12 years later has overshadowed the memory of our war with Mexico.
With the US victory a large part of what was Mexico became the part of the United States. By this war we gained the states of California and most of the Southwest. A fact that strains our relationship with Mexico to this day, This is my story of relearning that forgotten history. By the way, popular writer Opal Whiteley used to live near the base of this mountain & taught at the Doolittle School.
You may have sent and received dozens of Christmas cards with their images. Yet, how much do you really know about the Three Wise Men? This page is unique in telling the Magi's story through their own culture.
How to Quit Smoking AND Lose Weight!
If you or someone you loves smokes cigarettes, PLEASE show them this webpage.
I have stumbled upon a fairly easy way to do what seems impossible - quit smoking and lose weight.
It does not even require hard exercise or extreme diets. Believe it or not, I have lost over 50 lbs!
You can see before and after photos of me from 240 lbs down to 180. It's my own research (and body).
Steve was born in 1951 and grew up near Shreveport, Louisiana. He loved to read as a youth, often disappearing for hours into the woods with his dog and books. He worked railroad construction while at Louisiana State University. In 1975 he moved to Cottage Grove, Oregon. Working as a "gandydancer" made him appreciate the hard labor that the Asian railroad workers contributed. His sense of justice inspired him to research their stories.
In 1994, Steve founded the Opal Whiteley Memorial in Cottage Grove. Opal Whiteley was a best-selling nature writer in 1921 and grew up near Cottage Grove. He was later asked by the University of Oregon to assist in publishing Opal Whiteley's best-selling diary online. He collected dozens of historical photographs of the people and places Opal wrote about. The UO graciously provided support for his work as research assistant through a courtesy appointment. For over a decade he has shown his historic photos and news articles at the Oregon Asian Celebration, held each year in February.
Steve has worked for over 25 years with people who have autism and other psychiatric disabilities. He has also been been an advocate for the Association For Retarded Citizens (ARC), and the Oregon Mental Health Association. Steve has also given trainings in abuse reporting and client rights.


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California man sentenced for intent to distribute nearly 2,000 grams of heroin in Iowa
A California was sentenced on Wednesday after being arrested in Council Bluffs with intent to distribute nearly 2,000 grams of heroin.
California man sentenced for intent to distribute nearly 2,000 grams of heroin in Iowa A California was sentenced on Wednesday after being arrested in Council Bluffs with intent to distribute nearly 2,000 grams of heroin. Check out this story on desmoinesregister.com: https://www.desmoinesregister.com/story/news/crime-and-courts/2019/09/19/california-man-sentenced-nearly-2-000-grams-heroin-distribute-iowa-council-bluffs-jorge-machado-drug/2381102001/
Andrea Sahouri, Des Moines Register Published 9:00 p.m. CT Sept. 19, 2019
A California man was sentenced Wednesday to 10 years in prison followed by five years of supervised release for intent to deliver nearly 2,000 grams of heroin in Council Bluffs in January, a news release from the U.S. Attorney's Office for the Southern District of Iowa announced.
Jorge Alejandro Salazar Machado, 28, was arrested in Council Bluffs in January for possession of drug paraphernalia after police received a call that claimed he was selling marijuana on the 3000 block of W Broadway, according to court documents.
Police discovered a marijuana grinder and pipe in Salazar Machado's possession and performed a search warrant on his vehicle. Officers then found two packages containing the heroin in his car, the news release states.
Jorge Alejandro Salazar Machado sentenced for intent to distribute nearly 2,000 grams of heroin. (Photo: Provided by Pottawattamie County Jail/Special to the Register)
Salazar Machado pleaded guilty to possession with intent to distribute a controlled substance in May.
This is Salazar Machado's second federal drug conviction. He was sentenced in California to two years in prison in 2014 for trying to smuggle 4,500 grams of cocaine into the United States from the Mexico border, court documents show. He was released from prison in November 2017.
Salazar Machado told the court he is "focused on his faith and is ready for additional drug treatment," according to court documents.
Andrea Sahouri covers breaking news for the Des Moines Register. She can be contacted at asahouri@registermedia.com, 515-284-8247 or on Twitter at @andreamsahouri.
Your subscription makes work like this possible. Subscribe today at DesMoinesRegister.com/Deal.
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redpajama_set_name: RedPajamaCommonCrawl


Bali is the first area of the country to benefit from a US$2 million maritime security system donated by the Australian government.
Australian Home Affairs Minister Brendan O'Connor said his country had provided the communications system to help Indonesia combat maritime threats and cross-border crimes.
"Maritime security is a regional concern and the Gillard government is working with our neighbours to achieve the highest possible level of safety and security at sea," he said in a statement issued on Tuesday.
The A$2 million (US$1,971) surveillance project was switched on Tuesday and is called the Global Maritime Distress and Safety System.
"The new network will be put into action today with the opening of the first of four Indonesian Maritime Regional Coordination Centres in Karangasem in Bali," O'Connor said.
Issues the system will be employed to detect include people-smuggling, a contentious problem whereby a steady stream of asylum-seekers from war-torn countries such as Iraq and Afghanistan attempt to enter Australia after departing from parts of Indonesia, including Bali.
Illegal fishing would also be monitored, as would drug trafficking, two matters that plague the two neighbours.
"The VHF radio network provides more comprehensive reception of radio transmissions and can monitor maritime radio messages from anywhere within the archipelago," O'Connor said.
"With better monitoring, Indonesian authorities can deploy resources more swiftly and efficiently, potentially stopping crime and saving lives," he said.
Information picked up by the communications system and its operators will be sent to 12 Indonesian agencies as well as authorities in Australia.
The opening of the Bali centre will be followed by centres in other parts of the country – in West Timor, Maluku and easternmost Papua.
"Australia and Indonesia are working together to protect and police our adjoining waters to ensure the safety and security of the people of both our nations," O'Connor said.


Skid steers and track loaders are machines that change with the seasons. One skilled operator (with the right attachment) can use these tool carriers for just about anything, depending on the time of year — putting new lawns in during the spring, drilling holes for trees in the summer or brush cutting decaying foliage in the fall. Come winter, contractors can adapt their loaders for plowing snow, loading it into trucks and even salting facilities. You can move more snow in eight hours with a skid steer loader than you can in 20 hours with a truck. There's no need to back up or make Y-turns. You can just run circles around the competition.
The use of snow blower, snowplow, broom or bucket attachments can turn a skid steer or track loader (basically a skid steer with tracks) into a nimble snow removing expert. Just be warned: Winter weather tasks can be tough on both the machine and implements. A skid steer and track loader must be properly prepared to work in snow-covered conditions, as it will be battling poor visibility, cold weather, long hours and icy, slippery surfaces. So first off: Which unit is better? Dedicated tracks or tires?
Track Loader or Skid Steer?
Because of its dedicated undercarriage, track loaders have exceptional tractive effort allowing them to push and turn well, making them a solid choice for snow removal applications. With track loaders, the operator doesn't have to be as concerned with getting stuck or severely damaging landscaped areas due to the machine's greater flotation characteristics. Track loaders seem like a no-brainer for snow removal, but that comes at a price.
A big consideration for a track loader will be the type of track that will be used. If the track loader is equipped with a wide block-type track, it can easily break traction resulting in slippage and longer stopping distances, notes Caldwell. A track made specifically for winter applications will have a more aggressive lug pattern, providing better traction and resulting in reduced stopping distances and improved efficiency and performance.
"If you plan on using a skid steer, be mindful of the tire pressure," explains Caldwell. "As temperatures drop and the weather gets colder, tire pressure drops and should be checked regularly. As you lose tire pressure, the loader's ability to lift to dump height and push material will be diminished. One thing a contractor can do to greatly improve the performance of his skid steer is to equip his machine with tires specifically for winter applications. The ideal tire for snow removal is generally a narrow tire — approximately 6 ½ in. to perhaps 8 in. wide — increasing ground pressure.
Angle broom attachments are ideal for clearing sidewalks, small parking lots and driveways.
Cold temperatures can certainly affect machines in different ways. To ensure equipment stays in peak operating condition, contractors should be winterizing their compact equipment as soon as the first fall leaves hit the ground. Some of the most important winter checkup items for skid steers or track loaders are the fluids, oils and fuels. If a loader doesn't have the proper engine oil, engine coolant, hydraulic oil and fuel for operating in colder temperatures, then a contractor will find that the loader's performance isn't up to par. For example, it's important to have lighter engine oil that matches the cold outside operating temperatures.
As little as 2 in. of snow can create hazards on sidewalks, driveways, parking lots and other areas used for automobile travel and by pedestrians. Advanced planning is smart when considering the best attachments for your snow-removal needs, and there are several attachment options for use with snow and compact loaders. Many compact equipment owners simply use the bucket that was purchased with their skid steer or compact track loader, but that's not always the best option.
Besides buckets, brooms, blades and snow blowers are the most popular snow implements. Angle broom attachments are ideal for clearing sidewalks, small parking lots and driveways. An angle broom attachment will work best for snow clearing operations when snow is very dry and not very deep. Unfortunately, if there are more than a few inches of snowfall to clear or if the snow is heavy and wet, it becomes too difficult for the angle broom to push all of the snow off the surface being cleared. A snow push attachment is designed to simply "push" and clear large volumes of snow without leaving windrows or allowing for snow to spill over the top.
"The attachment is useless if you do not have a machine that is optimized for the application," says Brent Coffey, product manager of loaders with Wacker Neuson.
V-plow or -blade attachments can be used for snow clearing and removal as the blade can be adjusted in five different plowing configurations: 1) straight blade — this position can be used to back drag, remove windrows and performs as a general cleanup tool; 2) V-configuration — both blades on the attachment are pushed toward the rear of the machine, used to make a first pass during snow plowing; 3) scoop configuration — set with both blades pushed forward for use in trapping snow; and 4/5) left/right angle blade — setting the blade angle to the left or right allows the operator to widen an initial cut through the snow and continue pushing snow toward the edge of a worksite.
Designed to tackle the toughest snowfall and accumulation, the snow blower can have the ability to throw snow as far as 40 ft from the operator while removing snow from finished surfaces. It's one of many attachments that can be effective in the removal of snow, but only if the operator uses his or her attachment and tool carrier correctly.


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Rotary funds science lab for P.S. School (North)
Wednesday, July 14, 2010 Wednesday, July 14, 2010 - by Team MyTimes - Leave a Comment
By Ranjani R.
It was a joyous occasion for the students of P. S. High School (North) located at Mundakanniamman Kovil Street as they received a new science lab.
Rotary Club of Madras South has donated this fully equipped lab costing Rs.8 lakhs to the school as a part of their golden jubilee year celebrations.
Dignitaries present were the correspondent of the school Dr. Ganesan, District Governor of Rotary District 3230, Olivannan, president of the club P. Bowmick and the chief guest was President of P. S. Educational Society, C. V. Narasimhan.
The Head Master of the school U. S. Palanisamy thanked the club on behalf of the teachers, students and parents. The club has promised to adopt the school and help the school in the future as well.
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During its investor relations briefing, Nintendo revealed that its much anticipated Super Nintendo World theme park has a date.
The park, in collaboration with Universal Studios, will open its first wing in Japan in 2020, just in time for the Olympics. We won't have to watch swimming competitions! Woohoo!
Sorry. Swimming is actually pretty cool.
The theme park-within-a-theme park will arrive in other Universal Studios locations throughout the rest of the decade, but the launch in Osaka is being seen as the key first step to understand what will and won't entice fans.
The investor event revealed a couple more interesting tidbits.
Firstly, the upcoming Nintendo + Illumination (Despicable Me, The Grinch) collaborative Super Mario movie project is aiming for a release "around 2022." While that still seems a long ways away (it is!) at least the companies know not to rush through development of the animated film. Things could go wrong if they do.
Finally, it's kind of amazing that Nintendo didn't already have a retail location in its home country. The Nintendo Store in New York is wildly popular, and so the company has revealed that it's building a sister location in Tokyo named… Nintendo Tokyo. The building will be located in the Shibuya Parco, and be a "new base for communicating Nintendo information in Japan." It's schedule to open later this year in the Fall.


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Switching p53 states by calcium: dynamics and interaction of stress systems
By pronuvia | DNA Repair
Md. Jahoor Alam, Gurumayum Reenaroy Devi, Ravins, Romana Ishrat, Subhash M. Agarwal and R. K. Brojen Singh
The integration of calcium and a p53–Mdm2 oscillator model is studied using a deterministic as well as a stochastic approach, to investigate the impact of a calcium wave on single cell dynamics and on the inter-oscillator interaction. The high dose of calcium in the system activates the nitric oxide synthase, synthesizing nitric oxide which then downregulates Mdm2 and influences drastically the p53–Mdm2 network regulation, lifting the system from a normal to a stressed state. The increase in calcium level switches the system to different states, as identified by the different behaviours of the p53 temporal dynamics, i.e. oscillation death to sustain the oscillation state via a mixed state of dampened and oscillation death states. Further increase of the calcium dose in the system switches the system from sustained to oscillation death state again, while an excess of calcium shifts the cell to an apoptotic state. Another important property of the calcium ion is its ability to behave as a synchronizing agent among the interacting systems. The time evolution of the p53 dynamics of the two diffusively coupled systems at stress condition via Ca2+ shows synchronization between the two systems. The noise contained in the system interestingly helps the system to maintain its stabilized state (normal condition). However, noise has the tendency to destruct the synchronization effect, which means that it tries to restrict the system from external signals to maintain its normal condition. However, at the stress condition, the synchronization rate is found to be faster.
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Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor
Maria Rosario Fernandez-Fernandez, Dmitry B. Veprintsev, and Alan R. Fersht
S100B protein is elevated in the brains of patients with early stages of Alzheimer's disease and Down's syndrome. S100A4 is correlated with the development of metastasis. Both proteins bind to p53 tumor suppressor. We found that both S100B and S100A4 bind to the tetramerization domain of p53 (residues 325–355) only when exposed in lower oligomerization states and so they disrupt the tetramerization of p53. In addition, S100B binds to the negative regulatory and nuclear localization domains, which results in a very tight binding to p53 protein sequences that exposed the tetramer- ization domain in their C terminus. Because the trafficking of p53 depends on its oligomerization state, we suggest that S100B and S100A4 could regulate the subcellular localization of p53. But, the differences in the way these proteins bind to p53 could result in S100B and S1004 having different effects on p53 function in cell-cycle control.
Possible role of NF-kB and p53 in the glutamate-induced pro-apoptotic neuronal pathway
Mariagrazia Grilli and Maurizio Memo
Apoptosis is now recognized as an important component in many progressive and acute neurodegenerative diseases. Extracellular signals and intracellular mechanisms triggering and regulating apoptosis in neuronal cells are still a matter of investigation. Here we review data from our and other laboratories with the aim to elucidate the nature of some proteins which are known to be involved in cell cycle regulation as well as in promoting degeneration and apoptosis of neurons. The following molecules will be taken into consideration: NF-kB, p53, p21 and MSH2. These proteins are activated by neurotoxic experimental conditions which involve the stimulation of selective receptors for the excitatory aminoacid glutamate. Thus, we hypothesize their contribution to an intracellular pathway responsible for the glutamate- induced neuronal death. Identification of such mechanisms could be relevant for understanding the apoptosis associated with various neurodegenerative diseases as well as for developing novel strategies of pharmacological intervention.
PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kB, MAPkinase and p53 pathways
PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells
and regulates survival and chemoresistance via NF-kB, MAPkinase and p53 pathways
VL Grandage, RE Gale, DC Linch and A Khwaja
The phosphoinositide 3-kinase (PI3-kinase) signalling pathway plays a key role in the regulation of cell survival and proliferation. We show that the PI3-kinase/Akt pathway is constitutively active in primary acute myeloid leukaemia (AML) cells and that blockade by the selective inhibitor LY294002 reduces survival of the total blast population (mean 52%). The ERK/MAPK module is also constitutively active and treatment with the MAPKK inhibitor U0126 reduces cell survival by 22%. In 10 of 18 samples, PI3-kinase contributes to MAPK activation as incubation with LY294002 leads to a marked reduction in its phosphorylation. PI3-kinase inhibition reduces survival of the CD34 þ 38 AML progenitor subset by 44%, whereas MAPKK inhibition has little effect. Reporter assays in primary AML cells show that blocking PI3-kinase leads to a marked reduction of constitutive NF-kB activity and promotes p53-mediated transcription. This is associated with a synergis- tic interaction between LY294002 and Ara-C. An inducible activated form of Akt protects normal myeloid cells from Ara- C and etoposide-mediated apoptosis. These results show that blocking PI3-kinase has direct antileukaemic effects and potentiates the response to conventional cytotoxics via a number of targets including NF-kB, p53 and MAPK. Inhibitors of PI3-kinase and Akt may be useful in the treatment of AML.
p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner
Carlotta Giorgi, Massimo Bonora, Giovanni Sorrentino, Sonia Missiroli, Federica Poletti, Jan M. Suski, Fabian Galindo Ramirez, Rosario Rizzuto, Francesco Di Virgilio, Ester Zito, Pier Paolo Pandolfi, Mariusz R. Wieckowski, Fabio Mammano, Giannino Del Sal, and Paolo Pinton
The tumor suppressor p53 is a key protein in preventing cell transformation and tumor progression. Activated by a variety of stimuli, p53 regulates cell-cycle arrest and apoptosis. Along with its well-documented transcriptional control over cell-death pro- grams within the nucleus, p53 exerts crucial although still poorly understood functions in the cytoplasm, directly modulating the apoptotic response at the mitochondrial level. Calcium (Ca2+) transfer between the endoplasmic reticulum (ER) and mitochondria represents a critical signal in the induction of apoptosis. However, the mechanism controlling this flux in response to stress stimuli remains largely unknown. Here we show that, in the cytoplasm, WT p53 localizes at the ER and at specialized contact domains be- tween the ER and mitochondria (mitochondria-associated mem- branes). We demonstrate that, upon stress stimuli, WT p53 accumu- lates at these sites and modulates Ca2+ homeostasis. Mechanistically, upon activation, WT p53 directly binds to the sarco/ER Ca2+-ATPase (SERCA) pump at the ER, changing its oxidative state and thus leading to an increased Ca2+ load, followed by an enhanced transfer to mi- tochondria. The consequent mitochondrial Ca2+ overload causes in turn alterations in the morphology of this organelle and induction of apoptosis. Pharmacological inactivation of WT p53 or naturally occurring p53 missense mutants inhibits SERCA pump activity at the ER, leading to a reduction of the Ca2+ signaling from the ER to mitochondria. These findings define a critical nonnuclear function of p53 in regulating Ca2+ signal-dependent apoptosis.
p53: Good Cop/Bad Cop
Norman E. Sharpless and Ronald A. DePinho
Activation of the p53 transcription factor in response to a variety of cellular stresses, including DNA damage and oncogene activation, initiates a program of gene expression that blocks the proliferative expansion of damaged cells. While the beneficial impact of the anti- cancer function of p53 is well established, several re- cent papers suggest that p53 activation may in some circumstances act in a manner detrimental to the long- term homeostasis of the organism. Here, we discuss the significant participation of p53 in three non-mutu- ally exclusive theories of human aging involving DNA damage, telomere shortening, and oxidative stress. These "good cop/bad cop" functions of p53 appear to place it at the nexus of two opposing forces, cancer and aging. By extension, this relationship implies that therapies aimed to reduce cancer and postpone aging, and thereby increase longevity, will necessarily work either upstream or downstream, but not on the level of, p53.
Transcriptional Cross Talk between NF- B and p53
Gill A. Webster and Neil D. Perkins
Many cellular stimuli result in the induction of both the tumor suppressor p53 and NF- B. In contrast to activation of p53, which is associated with the induction of apoptosis, stimulation of NF- B has been shown to promote resistance to programmed cell death. These observations suggest that a regulatory mechanism must exist to integrate these opposing outcomes and coordinate this critical cellular decision-making event. Here we show that both p53 and NF- B inhibit each other's ability to stimulate gene expression and that this process is controlled by the relative levels of each transcription factor. Expression of either wild-type p53 or the RelA(p65) NF- B subunit suppresses stimulation of transcription by the other factor from a reporter plasmid in vivo. Moreover, endogenous, tumor necrosis factor alpha-activated NF- B will inhibit endogenous wild-type p53 transactivation. Following exposure to UV light, however, the converse is observed, with p53 downregu- lating NF- B-mediated transcriptional activation. Both p53 and RelA(p65) interact with the transcriptional coactivator proteins p300 and CREB-binding protein (CBP), and we demonstrate that these results are consistent with competition for a limiting pool of p300/CBP complexes in vivo. These observations have many implications for regulation of the transcriptional decision-making mechanisms that govern cellular processes such as apoptosis. Furthermore, they suggest a previously unrealized mechanism through which dysregulated NF- B can contribute to tumorigenesis and disease.
Bendable Electro-chemical Lactate Sensor Printed with Silver Nano- particles
Bendable Electro-chemical Lactate Sensor Printed with Silver Nanoparticles
Md Abu Abrar, Yue Dong, Paul Kyuheon Lee & Woo Soo Kim
Here we report a exible amperometric lactate biosensor using silver nanoparticle based conductive electrode. Mechanically bendable cross-serpentine-shaped silver electrode is generated on exible substrate for the mechanical durability such as bending. The biosensor is designed and fabricated by modifying silver electrode with lactate oxidase immobilized by bovine serum albumin. The in- sensor pseudo Ag/AgCl reference electrode is fabricated by chloridization of silver electrode, which evinced its long-term potential stability against a standard commercial Ag/AgCl reference electrode. The amperometric response of the sensor shows linear dependence with lactate concentration of 1~25 mM/L. Anionic selectivity is achieved by using drop-casted Na on coated on silver electrode against anionic interferences such as ascorbate. This non-invasive electrochemical lactate sensor also demonstrates excellent resiliency against mechanical deformation and temperature uctuation which leads the possibility of using it on human epidermis for continuous measurement of lactate from sweat. Near eld communication based wireless data transmission is demonstrated to re ect a practical approach of the sensor to measure lactate concentration portably using human perspiration.
Concerted Regulation of Wild-Type p53 Nuclear Accumulation and Activation by S100B and Calcium-Dependent Protein Kinase C
Christian Scotto, Christian Delphin, Jean Christophe Deloulme, and Jacques Baudier
The calcium ionophore ionomycin cooperates with the S100B protein to rescue a p53-dependent G1 check- point control in S100B-expressing mouse embryo fibroblasts and rat embryo fibroblasts (REF cells) which express the temperature-sensitive p53Val135 mutant (C. Scotto, J. C. Deloulme, D. Rousseau, E. Chambaz, and J. Baudier, Mol. Cell. Biol. 18:4272–4281, 1998). We investigated in this study the contributions of S100B and calcium-dependent PKC (cPKC) signalling pathways to the activation of wild-type p53. We first confirmed that S100B expression in mouse embryo fibroblasts enhanced specific nuclear accumulation of wild-type p53. We next demonstrated that wild-type p53 nuclear translocation and accumulation is dependent on cPKC activity. Mutation of the five putative cPKC phosphorylation sites on murine p53 into alanine or aspartic residues had no significant effect on p53 nuclear localization, suggesting that the cPKC effect on p53 nuclear translocation is indirect. A concerted regulation by S100B and cPKC of wild-type p53 nuclear translocation and activation was confirmed with REF cells expressing S100B (S100B-REF cells) overexpressing the temperature-sensitive p53Val135 mutant. Stimulation of S100B-REF cells with the PKC activator phorbol ester phorbol myristate acetate (PMA) promoted specific nuclear translocation of the wild-type p53Val135 species in cells positioned in early G1 phase of the cell cycle. PMA also substituted for ionomycin in the mediating of p53-dependent G1 arrest at the nonpermissive temperature (37.5°C). PMA-dependent growth arrest was linked to the cell apoptosis response to UV irradiation. In contrast, growth arrest mediated by a temperature shift to 32°C protected S100B-REF cells from apoptosis. Our results suggest a model in which calcium signalling, linked with cPKC activation, cooperates with S100B to promote wild-type p53 nuclear translocation in early G1 phase and activation of a p53-dependent G1 checkpoint control.
Glucose Metabolism, Lactate, and Ammonia Production by the Human Placenta In Vitro
Ian R. Holzman, Anthony F. Philipps, And Frederick C. Battaglia
Fifteen human placentas were obtained at term. Placental frag- ments were incubated in a bicarbonate-buffered Earle's solution. Additions of glutamate (1 mM) or glutamine (1 or 2 mM) were made. All incubations showed a net utilization of glucose. There was a striking variability among placentas in the net glucose utilization rate (1.27 pmoles/g/hr-11.44 pmoles/g/hr, coefficient of variation = 62%). The intraplacental coefficient of variation in glucose utilization was only 14%. All placental incubations showed a net production of both lactate (mean = 7.5 pmoles/g placental wet weight/hr) and ammonia (mean = 3.5 prnoles/g placental wet weight/hr). There was no correlation between lactate or ammonia production and glucose utilization. The addition of sodium gluta- mate (1 gmole/ml) produced no change in glucose utilization or ammonia production. The addition of glutamine (1 and 2 pmoles/ ml) produced a significant increase in ammonia production over that found in the controls, but no change in glucose utilization. Incubation with 2 pmoles glutamine/ml demonstrated an increase in lactate production. All incubations showed a striking increase in ammonia concentration after 45 min of incubation.
Individual placentas may differ markedly in their ability to utilize glucose in an in vitro system. Ammonia production may be a normal metabolic endproduct in a tissue lacking an active urea cycle or a byproduct of the purine nucleotide cycle
SAC Calcium: For Mitochondrial Dysfunction
Calcium Ion for Dentistry
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<< Back to Film Fests & Events
CC: Dust in the Wind (1986)
2019/20 SEASON!
Thursday, February 13, 2020 - Thursday, February 13, 2020
Dust in the Wind (1986)
Thursday, February 13, 2020 @ 7:00 PM
Globe Cinema - 617 8 Avenue SW, Calgary, AB
$12 General | $10 Members/Seniors/Students | $40 5-Pack Punch Pass | $99 Season Pass
Two young lovers from the village give up high school to work in Taipei, in a nostalgic portrayal of the changing Taiwan of the early 1970s.
The third of Hou Hsiao-hsien's "coming of age" trilogy, Dust in the Wind (1986) tells the universal and archetypal story of a young couple from a small village who decamp for the big city, little prepared for the struggles that they will encounter upon arrival.
Hou was born in southeast China in 1947, but his family fled to Taiwan within a year, a not uncommon exigency in a period of civil war. A painful experience of cultural and geographical dislocation would come to inform Hou's sensibility from an early age, as would a general spirit of drift and lassitude. After toiling for a time on the periphery of the nascent Taiwanese commercial film industry, Hou directed his highly regarded "coming of age" trilogy from 1984 to 1986, culminating in Dust in the Wind. In retrospect, these films would come to be considered instrumental in the birth of a Taiwanese New Wave, one of the central developments in World Cinema of the 1980s and 1990s.
Dust in the Wind references cinema's connection to industrial modernity and Taiwan's rapid modernization in the 1970s. Large-scale migration of farmers and villagers to major urban centres, trains, supplanted geography, transience and dispossession. Both universal in theme and deeply personal in nature, Dust in the Wind is one of Hou's most celebrated and revered works, demonstrating that both young love and the city itself can break your heart in any number of ways.
- Written by Jason Wierzba
SPOTLIGHT: TAIWANESE NEW WAVE
In the early 1980s, Taiwanese cinema was at a crossroads. Nobody was watching locally made melodramas or kung fu movies anymore, instead opting for films from Hong Kong. Taiwanese society was also rapidly changing, with soaring high-tech economic growth driving people into the concrete jungles of Taipei and the cities. To revitalize the film industry, the state-run Central Motion Picture Corporation turned to a time-tested method to revitalize national cinemas – give the reins over to young filmmakers. These filmmakers, including Hou Hsiao-hsien, Edward Yang, and Tsai Ming-liang, pursued a radical break from the previous stylistic and aesthetic traditions, favouring location shooting, long takes, and deliberate editing to reflect the rapidly changing world around them. Each responded to the alienation wrought by globalization in their own unique ways: Hou with pensive reflection, Yang with meticulous exhumation, and Tsai with melancholy detachment. With this series, Calgary Cinematheque presents five key films from one of film history's most influential movements.
About Calgary Cinematheque
We are a non-profit film society dedicated to presenting significant, challenging, and essential works of cinema art in Calgary. During our season, which runs from October to April, we screen films weekly, in curated programs which situate each film in a thematic and historical context. We do this because we believe cinema is an essential form of artistic, social, and political expression. Audiences should be able to engage with a wide range of cinematic expression, not only with what is commercially viable. We believe in the power of sharing these experiences with other people in a theatrical setting and we strive to cultivate a community around that experience.
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UN reports progress in rehabilitating child soldiers from civil war in Nepal
6:24 am November 27, 2010| Last Modified: 6:24 am November 27, 2010
Kathmandu, Nepal (BBN)– A Security Council working group on Friday reported significant progress on the release and reintegration of thousands of Nepalese child soldiers who fought in the decade-long civil war between the then-royalist government and Maoist insurgents.
During "a very constructive" week-long visit, the Working Group for children and armed conflict conferred with the government and the Unified Communist Party of Nepal-Maoist (UCPN-M) on the Action Plan the two signed with the United Nations last December for the re-integration of minors released by the Maoist army.
"I am particularly pleased to report on the commitments that the UCPN (Maoist) and other political party officials made during our discussions," Mexican Ambassador Claude Heller, chairman of the Working Group, told reporters in Kathmandu on Friday.
"The Working Group feels these commitments constitute a significant step in the right direction for the children and youth of Nepal," he said, citing UPCN-M Chairman Pushpa Kamal Dahal's agreement to significantly strengthen coordination with the UN to monitor implementation of the Action Plan so as to address remaining challenges in its execution.
Under this agreement, the UN Monitoring Team will meet with the UCPN-M on a regular basis to address the concerns that have been reported.
On talks with the government, Mr. Heller noted that the Ministry of Peace and Reconstruction pledged to press for Cabinet approval and speedy implementation of the national plan to rehabilitate and reintegrate child solders and other conflict-affected children.
Chairmen of political youth wings agreed to work with the UN to find ways to end the use of children below the age of 18 in potentially violent political activities and to exclude schools, school children and school personnel from strikes and other work actions.
BBN/SI/AD-27Nov10-12:25 pm (BST)
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Vodkamom: Run, run as fast as you can; we can't stop looking for the gingerbread man.
Run, run as fast as you can; we can't stop looking for the gingerbread man.
We were working on a gingerbread man activity at my center this morning, excitedly chatting about where the children thought our own gingerbread man might be hiding.
Already, she's sick of school? I see another handful in the making.
is it really your birthday or is this the sarcastic "happy bday to me cause this isn't my day" thing? If it really is then Happy Happy!
oh and I found this article through the grapevine. I know you teachers do so much and some parents think their kids are angels so it makes your job even harder.
Maybe she and Frank can get married when they grow up - just quit teaching before their kids get to you!
Happy Birthday! Hope you had time for a little nip and not just the little nippers in your class.
How did I miss your birthday?!? Hugs from far away dear lady!
Francis sounds like my youngest boy, always sooooooooo sick of school. I can't listen to it anymore, I'm all like just deal with it dude!
PS. Who won the ipad? Did I miss the winner announcement?
-->So far, my child isn't "Frank" in his pre-K class but I do wonder what interesting things he may say during the day.
He got in trouble yesterday for talking when it was quiet time in the after-school program. I told him he needed to pay attention.
Has anyone told her she's got a minimum of twelve years after that?
Happy, happy birthday! I hope this next year brings wonderful gifts to you! I think this will be *your* year.
Yeah, you'd better git while the gittin's good!
My eyes keep playing tricks on me - lawd! I read the following sentence: "the children can hardly contain their excitement"
as ?The children can hardly contain their excrement"
OMG LAUGHING ...ewww .... kat . . . ugh. lawd.
Of course you know there's nothng new under the sun. In 1950 my brother told my mom he was sick of school. "Well, just stand it for one more day." "OK." But kids were so naive then. He was only sick of school, not "so sick of this school."
I am a kindergarten teacher from Alberta and a friend introduced me to your blog. I loved the post about your sister and her new hearing aids- totally touching.
You write a great blog and I know I am coming back to visit you again.
Poor thing!! I feel like that sometimes - like the few horrible times I've had to go to the DMV...ick!
My kids are mortally offended at having to go back to school. (It's day 3 for us). Meanwhile I've bought some clogs to do some Irish dancing. Sweet Jesus, they've gone back to school!
Too funny! After the first day of school my 8th grade daughter and her friends were all posting on FB how many days until school was over.
I want to be in your class and draw pictures.


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Zbigniew Leszek Rakowiecki (ur. 14 czerwca 1913 w Łasku, zm. 5 sierpnia 1944 w Warszawie) – polski aktor filmowy i teatralny, żołnierz powstania warszawskiego. Mąż aktorki Karoliny Lubieńskiej.

Życiorys
Studiował na Akademii Sztuk Pięknych i w Szkole Nauk Politycznych, nie ukończył studiów. Zadebiutował w drugiej przedwojennej ekranizacji powieści Stefana Żeromskiego Dzieje grzechu z 1933. Występował w chórze rewelersów, oraz w teatrach rewiowych Warszawy: "Teatrze na Kredytowej", w teatrze "Hollywood", w "Wielkiej Rewii", w "Cyruliku Warszawskim" i w teatrze "Ali-Baba". W sezonie 1938/39 był zaangażowany przez Stefana Jaracza do Teatru Ateneum".

Podczas II wojny światowej walczył jako żołnierz w kampanii wrześniowej, a po jej zakończeniu występował w warszawskich teatrach jawnych. Podczas okupacji niemieckiej, służył w Armii Krajowej. Uczestniczył w powstaniu warszawskim, w stopniu strzelca, na Ochocie w 403 plutonie. Został rozstrzelany przez rosyjskich żołnierzy z Brygady SS "RONA" 5 sierpnia 1944 przy ul. Radomskiej 14.

Spoczywa na Cmentarzu Powstańców Warszawy na Woli w kwaterze 73.

Filmografia
 1933: Dzieje grzechu
 1935: Kochaj tylko mnie jako tancerz
 1936: Fredek uszczęśliwia świat jako Fredek
 1936: Papa się żeni jako Jerzy Murski
 1939: Włóczęgi jako Tadek
 1939/1940: Żołnierz królowej Madagaskaru jako Władzio Mącki
 1939/1941: Ja tu rządzę jako hrabia Józio Lulewicz

Spektakle teatralne
 1933 – No, no, Nanette, "8.30"
 1934 – To lubią kobiety, "8.30"
 1935 – Dla ciebie Warszawo
 1936 – Całus i nic więcej, "Wielka Rewia"
 1936 – Gaby, "8.15"
 1937 – Taniec szczęścia, "8.15"
 1937 – Colette, czyli miss Loteria, "8.15"
 1938 – Krysia leśniczanka, "8.15"
 1938 – Roxy i jej drużyna, "8.15"

Zobacz też
 Polegli w powstaniu warszawskim po stronie polskiej

Przypisy

Bibliografia

Linki zewnętrzne

Polscy aktorzy filmowi
Polscy aktorzy teatralni
Uczestnicy kampanii wrześniowej (strona polska)
Żołnierze Armii Krajowej
Powstańcy warszawscy
Ludzie urodzeni w Łasku
Ofiary rzezi Ochoty 1944
Pochowani w Warszawie
Urodzeni w 1913
Zmarli w 1944

redpajama_set_name: RedPajamaWikipedia


Andhadhun is another thriller in Sriram Raghavan's directorial and my god this one is quite something which most of us didn't expect to turn out like this.
Thrillers happen to be the extinct genre in Bollywood and they were only famous during the black-&-white era which was proven to be quite successful. As years passed by, the frequent genres of the industry like action, romance and comedy started to die down and then Sriram Raghavan came from the oblivion and made films like these. Andhadhun is something which is quite unexpected from the director who has a craft of keeping the audience hooked with his stories.
The film revolves around Akash (Ayushmann Khurrana) a blind pianist, who lives his life to the fullest despite his disability being an obstacle. His perfect life involves Sofie (Radhika Apte), who tends to fall in love with his musical creations. One fine day, he is invited by a yesteryear actor (Anil Dhawan) who carries a deep lust for his wife Simmi's (Tabu) crab delicacy to play a piece for them. Trouble lurks when a murder is committed and the witness is none other than Akash. While watching the film, you get to see a myriad of characters ranging from a cop investigating the murder, his boisterous wife, a corrupt doctor which tend to create an impact.
Ayushmman Khurrana had a track record of playing a lead in most of the satirical comedies so far. This film is completely out of his comfort zone and he breathes into the skin of a blind pianist, ranging from the style of walking to playing the piano like a pro. This man has a very bright future in the industry.
Radhika Apte has not been given proper screen time compared to her previous ventures which have been loved by most of the fans. But she does give justice to her role. She particularly shines the best in most of the romantic moments with Ayushmann and their chemistry is quite sparkling and hot as lava.
Tabu has a knack of giving mostly critically acclaimed roles in her two-decade career and this is the standing proof that she is prepared to impress the critics with her unique style of acting. With this film, she acts naturally when she seduces her husband while cooking a crab delicacy for him.
Anil Dhawan looks comical in most of the scenes when he makes a grand entry at his home with flowers and wine with a gun in his other hand. This scene follows with a sequence of jazz music which is the main core of the film and it keeps the energy of the film fueled.
The director has utilized every bit of frame in his latest venture and he never fails to impress us, not even in one bit. During the film, especially the murder sequences, instead of the usual score we tend to hear some classic songs of Kishore Kumar and Mohammed Rafi in the background which denotes the style of neo-noir filmmaking. We wish to see more films like this in the near future.
The songs are quite awesome especially, the theme song which is present throughout the film and the title song sung by Raftaar adds a unique punch into the film. You can listen to them frequently on repeat if you love these awesome songs.
Overall, this film is a must-watch to every suspense and edge-of-the-seat thriller lovers in India.


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Flights RESUMED at Gatwick Airport after reports of another drone sighting - live updates
The airport says it is suspending airfield operations as a precaution
Alexander BrockSenior Reporter
Ann YipSenior reporter
Passengers were stranded at the airport throughout Thursday (December 20) (Image: Victoria Jones/PA Wire)
Gatwick Airport says it has resumed airfield operations after a brief suspension following reports of another drone sighting.
It announced on social media that it had suspended operations at 5.47pm on Friday (December 21).
However, at 6.21pm it said "flights have resumed".
Earlier on Friday the airport had announced that its runway is "available" following the 36 hours of travel chaos caused by drone sightings.
However, it said a limited number of aircraft are scheduled for departure and arrival.
Flights at Gatwick Airport were grounded on Wednesday evening (December 19) due to sightings of drones flying in the airspace.
All flights were suspended after two drones were spotted flying over the airfield at around 9pm, the airport said in a statement.
A further of sighting of drones has forced the airport to close the runway from 3.45am on Thursday (December 20).
Anyone flying from Gatwick on Friday is advised to check the status of their flight.
Have you been affected by the delays? Email your story at ann.yip@reachplc.com.
We will bring you live updates below on this developing situation as we get them.
For all of today's breaking news visit our news section, or follow us on Facebook or Twitter.
You can also keep up to date with the latest news from across the county via the free Surrey Live app.
You can set up your app to see news and events from your area, and receive notifications for any breaking news.
Join the Surrey Live 'Traffic and Travel' group
We've created a Facebook group for people who live in and travel through the county to keep up to date with what's happening on the roads and trains.
We will keep you informed about the latest news that affects your journey to work or school, as well as at the weekend, whether it is planes out of Heathrow Airport or Gatwick Airport; South Western Railway, Southern or Great Western Railway trains; or traffic on the M25, M23, M3, M4, A3, A24, A31, A25, A22 or one of Surrey's many other roads.
We'll also let you know in advance if there are any roadworks, railway engineering works or closures you should know about.
Join the group here.
Round-up of Gatwick reopening 14:39
Sussex Police: Progress in investigation 07:39
Flights begin to resume at Gatwick 07:09
Disruption ruining Christmas for Surrey families expected to continue overnight 19:04
Gatwick CEO: Events 'highlight a wider strategic challenge for aviation in this country' 17:53
Flights RESUMED
Okay, so Gatwick has just announced that flights have resumed at the drone-afflicted air hub.
A statement released at 6.21pm said:
Flights have now resumed at Gatwick following a reported drone in the area. While we investigated, airfield movements were suspended.
This was a precautionary measure as safety remains our main priority.
The military measures we have in place at the airport have provided us with reassurance necessary that it is safe to reopen our airfield.
*Breaking*
Gatwick Airport announced on Twitter at 5.47pm on Friday that it has "suspended airfield operations" after another drone sighting.
Gatwick is investigating reports of a drone sighting. As a precaution we have suspended airfield operations. More to follow.
— Gatwick Airport LGW (@Gatwick_Airport) December 21, 2018
'Persons of interest' identified, says BBC
A BBC journalist has tweeted that Steve Barry, Sussex Police assistant chief constable, has told him that "persons of interest" had been identified as part of the investigation:
Ryanair flights diverted, more flight cancellations
Gatwick, which this morning been saying that 140 flights were cancelled today, have upped that figure to 155.
Traffic news provider Inrix also states that all Ryanair operations have been diverted to Stansted.
Round-up of Gatwick reopening
Can't be bothered to scroll through all our updates? We've compiled all the important bits into this story:
Safety measures brought in, says police
A number of safety measures have been brought in to enable Gatwick Airport to re-open on Friday (December 21), police have said in a statement.
Assistant Chief Constable Steve Barry said:
We are really pleased that the airport has re-opened. The number of options now available to help us detect and mitigate the threat from the drone has given us increased confidence in keeping people safe.
This, and the fact the last confirmed sighting was before 10pm last night, is reassuring for passengers who have been disrupted by this criminal behaviour.
This has been a particularly challenging situation. We have looked at everything possible that we can deploy to mitigate this threat and we have a range of measures, of differing levels of sophistication, in place which puts us in a much better position. We are being supported by Surrey Police and Metropolitan Police, as well as the military.
I cannot guarantee that another drone isn't going to pop up and disrupt the airport. The situation is being kept under review but we are in a much more positive situation than yesterday. The runway is open and we hope to keep it that way.
We are working very closely with Gatwick Airport Limited and the Civil Aviation Authority and are in close consultation with the government and other agencies in an effort to keep people safe.
We have significantly increased our police presence to support the operation.
We are now actively carrying out a criminal investigation and have a number of lines of enquiry. This has been a deliberate act to endanger the airfield and aircraft, a really serious offence that carries significant sentences, and we are doing all we can to find those responsible.
Anyone with information about the incident or who may have suspicions about the drone operators is asked to report online or call 101 quoting Operation Trebor. If you see anyone acting suspiciously in the area of the airport, please dial 999 immediately."
Crawley resident says he is not happy about Gatwick closure
Crawley resident Jeremy Taylor has spoken out to say that local anti-Gatwick expansion group, Communities Against Gatwick Noise and Emissions (CAGNE), has "caused an uproar over their apparent joy" at the Gatwick closure.
Mr Taylor clarified that the group does not represent him or anyone he knows.
He added: "I would also hope that night restrictions are suspended at Gatwick until the backlog is clear."
CAGNE said in a statement earlier (also published in this blog):
Residents woke to silence from Gatwick Airport on 20th December, offering a glimpse of the tranquillity that they use to enjoy before Gatwick introduced concentrated flight paths (2013-14) and increased the number of aircraft movements.
For tens of thousands of residents of Sussex, Surrey and Kent they enjoyed some respite from the aircraft motorways above their homes that usual, in part, blight their lives day and night, and due to an out of date law, are powerless to take legal action to stop the flights from impacting their wellbeing and house value.
Although CAGNE, an umbrella community group, does not condone the irresponsible behaviour of flying drones near an airport potentially endangering lives, it was an early Christmas present for those that suffer aircraft noise.
Skyscanner creates real time page to help travellers
In light of the disruptions, Skyscanner has created a real time page for travellers to check arrivals and departures for all flights in and out of the UK.
The website revealed that today (Friday, December 21) is the busiest day of the year for outbound travel from the UK.
It said that following the drone disruption at Gatwick, there has been an uplift in traffic to the site as passengers seek alternative flights. From 8pm last night (Thursday, December 20), there was an uplift in traffic compared to the same last week, which peaked at 1am this morning where the travel site saw a 31% increase in user's week on week.
Former Surrey Live reporter gets ready for flight
Though the airport has now reopened, there are still many (140) cancelled flights today, meaning that thousands of people still being affected today. For many families, the damage has already been done. We spoke to two families yesterday who had to cancel their trip altogether because they weren't able to find any alternative flights to get on.
But some passengers are relieved to discover that their flights will be going ahead today. It's happy news for our former reporter Joe Burn, now a reporter at the Isle of Wight County Press, who will be able to fly to America this morning to be reunited with his girlfriend for Christmas.
You could receive compensation from insurance companies, says Grayling
Airlines may not have to pay compensation, but you should be able to receive compensation from insurance companies, according to Transport Secretary Chris Grayling in a Daily Mirror report.
He told the BBC:
It goes beyond what the airline is responsible for. This is something that should be covered under travel insurance policies.
But we will talk to the insurance industry today to make sure they treat claims reasonably. It's certainly not linked to terrorism in the conventional sense.
This is something I would hope the insurance industry would take an enlightened view about."
Most travel insurance policies cover for travel delays, usually if your flight is delayed by more than 12 hours due to factors from adverse weather to industrial action, the Mirror said.
Advice for passengers from the BBC
Ben Thompson, BBC correspondent offered some sound advice on BBC Breakfast:
The airline should be your first port of call. Speak to your airline because they have to either re-book you on a flight, if its available, but they've also got to give you a full refund if you decide you don't want to travel at all, if you want to cancel.
Crucially, you're not going to get any compensation. The civil aviation authorities decided that this is unprecedented, it's out of anyone's control. You're not entitled to compensation.
And thirdly, you are entitled to reasonable expenses, and I use the word reasonable very carefully here. If you've got any expenses keep your receipts for them, make sure that you can account for everything. You can submit that to the airline and you may get your money back. But the key thing there is 'reasonable', don't go overboard. It's meals, it's maybe a hotel overnight, but that is about it.
Airlines not obliged to pay compensation
The Civil Aviation Authority has offered the following advice to passengers affected by the Gatwick disruption:
Under EU261 regulations, passengers that no longer wish to take their flight can contact their airline for a refund. For those passengers that do still wish to fly, we advise them to contact their airline to understand the options available.
Given the reasons for the current disruption at Gatwick Airport, the Civil Aviation Authority considers this event to be an extraordinary circumstance. In such circumstances airlines are not obliged to pay financial compensation to passengers affected by the disruption.
Technology to stop drones is just emerging, says Transport Secretary
Transport Secretary Chris Grayling spoke to BBC Breakfast this morning.
When asked whether it was just one drone, or multiple drones, he said:
It's thought to be a small number of drones in the plural. There were more than 40 sightings over the period the airport was closed, so we can't be certain whether it was one or more.
He said airports across the country would need to learn from the Gatwick incident:
"It's clearly a kind of disruptive activity that we've not seen before. This kind of incident is unprecedented anywhere in the world, the disruption of an airport in this way. We're going to have to learn very quickly from what's happened. I plan to convene discussions with other airports around the UK very quickly indeed, so that they know what's happened, they understand what lessons need to be learned, and we put in place every measure we possibly can to ensure this can't happen again.
In response to a question asking why the UK had "waited" until the incident happened to introduce measures to stop drones, he said:
The reality is that this technology, the ability to stop drones is really only just emerging.
A small number of airports around the world have started to bring in systems that could help, might not solve a problem like this, but could help.
So it's not a question of waiting to introduce the technology, the technology is literally only just appearing. One of the things we're going to have to learn from this is what the existing technology can do, what else needs to be done. But there certainly isn't a straightforward, commercial, off-the-shelf solution that automatically solves all problems.
Patrols in Heathrow in light of Gatwick incident
A spokesman for Heathrow has confirmed that there are currently additional patrols in place at Heathrow as a result of the incident at Gatwick.
Additional measures are going to be slightly more visible. There will be police cars doing patrols, there might be some helicopters heading round, but it's mainly on foot.
She also confirmed that Heathrow did have its own measures in place if something similar were to happen there. But the spokesman said they were not able to disclose any details.
Incident is not terrorism-related, says police
Sussex Police released a statement at 8.22pm last night saying that "nearly 50 reports of a drone being flown illegally around the airport have been received since mid-evening on Wednesday".
Detective Chief Superintendent Jason Tingley, from Sussex Police specialist crime command, said: "Our assessment, based upon the information that we have available to us, is that this incident is not terrorism-related."
Anyone with information about the incident or who may have suspicions about the drone operators is asked to report online or call 101 quoting Operation Trebor. If you see anyone acting suspiciously in the area of the airport, call 999 immediately
Know the drone laws
UK drone rules changed on July 30, making it illegal for anyone to fly a drone above 400ft (120m) and within 1km of an airport or airfield boundary.
Drones must also be 150ft (50m) from people and properties and 500ft (150m) from crowds and built up areas - according to dronesafe.uk
140 flights cancelled today
140 flights have been cancelled today, 18% of the original plan - according to Inrix, traffic news provider
Gatwick say it has been working to put measures in place
A statement by Gatwick Airport, as of 8am:
Gatwick's runway is currently available having reopened at 6am. A limited number of aircraft are taking off and landing at Gatwick this morning but our departures and arrivals rate is currently very restricted to just a few runway movements every hour so passengers must expect delays and cancellations again today. Gatwick continues to strongly advise passengers to check the status of their flight with their airline before travelling to the airport.
Overnight we have been able to work with partners, including Government agencies and the Military to put measures in place which have provided the confidence we needed to re-open the runway and ensure the safety of passengers, which remains our priority.
We continue to provide welfare and information to all disrupted passengers who are at the airport and have had teams in throughout the night. Our priority today is to get our operation back on track so that people can be where they need to be for Christmas, and we will update as more information becomes available throughout the day.
How could we deal with drones?
Police had been reluctant to shoot down the drone(s) yesterday because of the "risk of stray bullets", said Chris Woodroofe, Gatwick's chief operating officer.
In a report by the Daily Mirror, Mr Woodroofe said police had advised "it would be dangerous to seek to shoot the drone down because of what may happen to the stray bullets."
Chris Foxx, the BBC's technology correspondent, said there are some "left field" ways to bring down a drone, including lasers or nets.
He said: "At the more Star Wars end of things, you can use a laser to fire down drones.
"You don't really want to be shooting missiles near airports, especially if there are planes coming into land.
"Boeing is one company that has been testing a laser that can track a drone, heat up the battery and cause it to set on fire to bring it down."
Another method that has been developed is a larger drone capable of catching the smaller drone with a net.
Some police forces have trained eagles or falcons to catch rogue drones.
What are the laws on drones?
Chris Grayling: More than 40 sightings of drones
Transport Secretary Chris Grayling told BBC Breakfast: "There were more than 40 sightings over the period the airport was closed."
Sussex Police: Progress in investigation
Steve Barry from Sussex Police spoke to BBC Breakfast.
He said that the last drone sighting was just before 10pm last night and that police had "made a lot of progress overnight".
He said: "We're in a much better position today". But he confirmed that no one had been arrested yet.
Police have a number of lines of enquiry.
A Glimpse of the Past for Rural Communities
Local anti-Gatwick expansion group, 'Communities Against Gatwick Noise and Emissions (CAGNE), have been enjoying the silence from Gatwick.
In a statement, they said:
Flights begin to resume at Gatwick
Flights have resumed at Gatwick, but the airport are continuing to advise passengers to check the status of their flights before travelling.
A statement from Gatwick Airport says:
Gatwick's runway is currently available and a limited number of aircraft are scheduled for departure and arrival.
Gatwick continues to advise passengers to check the status of their flight with their airline before travelling to the airport as departures and arrivals will be subject to delays and cancellations.
Disruption ruining Christmas for Surrey families expected to continue overnight
The disruption at Gatwick Airport is continuing to ruin Christmas travel plans for thousands of people - including families in Surrey.
There is no indication, as of yet, when the airport runways might re-open, but the airport said it expects the chaos to continue for the rest of the evening and into Friday (December 21).
You can read the full story here.
Former Surrey Live reporter could be affected by airport chaos tomorrow
Joe Burn, our former colleague and now reporter at the Isle of Wight County Press, hopes to be able to fly to Los Angeles tomorrow to be reunited with his girlfriend for Christmas.
As if it wasn't bad enough I have to take a ferry off the Isle of Wight tomorrow morning and then two trains that you just know will be delayed in some sort of way, some spoiled Surrey/Sussex brat has unwrapped his Christmas present early and decided to wreak more havoc on the nation than Michael Gove's Brexiteering. Gatwick, please sort it out, can't be that hard.
When asked what his plans are if his flight tomorrow is cancelled, he said:
I will camp out in a Wetherspoons and wait for it all to blow over I suppose.
Gatwick CEO: Events 'highlight a wider strategic challenge for aviation in this country'
Stewart Wingate, Chief Executive Officer at London Gatwick said at 5.40pm:
On behalf of everyone at Gatwick I would like to repeat how sorry we are for the inconvenience this criminal behaviour has caused passengers and we share their real anger and frustration that it has happened. This is a highly targeted activity which has been designed to close the airport and bring maximum disruption in the run up to Christmas. We are working very closely with the police and the security services to try to resolve this for passengers.
We hope passengers appreciate that we must and will always prioritise their safety over everything else. We are all working flat out to minimise inconvenience and have additional staff in both terminals assisting passengers who are waiting. Regrettably we are still not in a position to say when it will be safe to reopen the airport. As soon as we can we will.
To recap the facts: We first had reports of two drones flying in and around the airfield at 21:03 last night. As a result, we took immediate steps to close the runway in accordance with our airport safety protocols. We obviously wanted to be in a position to reopen the airport again as quickly as possible. We are still receiving drone sightings in and around the Gatwick airfield. Therefore, until we are confident that the issue has been resolved it would clearly not be in the interests of passengers to do so as we could be jeopardising their safety.
So regrettably, for the time being, the airport will remain closed as a result of this criminal activity. While some airlines have cancelled all flights up to 7pm tonight, we would encourage all passengers to check the latest information on their flights directly with their airline or on the Gatwick website.
We are working hard with both the police and Government agencies as we seek to resolve this situation. We know that everyone, including Government, appreciates the severity of the situation and are very grateful for the active role that the police are taking to try and resolve this. We all recognise the urgent need to take the necessary steps that can lead to services getting back to normal as quickly as possible.
Although not for today, these events obviously highlight a wider strategic challenge for aviation in this country which we need to address together with speed - the aviation industry, Government and all the other relevant authorities. It cannot be right that drones can close a vital part of our national infrastructure in this way. This is obviously a relatively new technology and we need to think through together the right solutions to make sure it cannot happen again.
In the meantime all our focus is on sorting the current challenge and getting services back to normal for passengers. At the moment, I am not in a position to say with certainty when that might be but everyone is doing whatever they can to help make that happen.
Walton mother and son won't be spending Christmas with rest of family
Valerie, 35, from Walton, and her seven-year-old son had been planning to catch a flight to Bordeaux to spend Christmas with family. But they will now have to spend Christmas here in Surrey.
I didn't stay at Gatwick as my flight has been cancelled and there was no other flight for my destination (Bordeaux) until December 26 (even full when I tried to transfer my tickets ) and now me and my seven-year-old son are very upset are we are stuck here for Christmas.
We were planning to see family.
We go only twice a year and they (my family) are all very sad, especially my nephew who is the same age as my son and they always look forward to see other. So now, we have to deal with lots of tears.
easyJet cancels all flights today
As of 5pm, easyJet has issued the following statement:
We are making every effort to get people to their destination at this important time of the year, but following reports of drones flying over Gatwick Airport, the runway remains closed and all flights are currently suspended. At this stage there is no indication of when the airport might re-open and as a result we have cancelled all flights due to operate to or from London Gatwick today.
We expect disruption to continue into tomorrow and so advise all customers flying to and from London Gatwick tomorrow to check the status of their flight on our Flight Tracker www.easyjet.com/en/flight-tracker or via the app. Customers on cancelled flights, will be entitled to a free of charge transfer to an alternative flight and hotel accommodation if required. We will also reimburse any reasonable expenses incurred by passengers who arrange their own comparable alternative transport.
Whilst the situation is outside of our control, we recognise how frustrating this is for everyone involved and would like to apologise to passengers for the disruption to their travel plans.
The safety of its passengers and crew remains our highest priority."
Flights cancelled up to 7pm, Gatwick confirms
Gatwick has provided a statement, as of 5pm:
All flights to and from Gatwick are suspended. If you are due to fly later today or are meeting someone from a flight, please do not travel to the airport without checking the status of your flight with your airline first.
Gatwick Airport's runway remains unavailable because of continued drone sightings and some airlines have cancelled all flights up to 7pm. There is significant disruption at Gatwick today as a result of what appears to be a deliberate attempt to disrupt flights, and we anticipate disruption to continue throughout the day and into tomorrow.
We are extremely disappointed that passengers are being affected by this especially at such an important time of year. We are working with our airlines to put plans in place to recover our operations once given the go ahead to re-open our runway. We are prioritising the welfare of those at the airport by deploying staff into our terminals to look after people as best we can.
If you are meeting someone from a flight, please do not come to the airport. Use our live flight information for up-to-date about flights or check with the airline.
Once again, we apologise to our passengers for the continued disruption. Safety is our absolute priority.


Are your lecture notes confusing you? Finding it hard to write your essay? Struggling to adapt to independent learning?
This Help! section is designed to give you a fresh perspective and ways to overcome any difficulties you may have regarding studying at university.
Help! I don't know what to write in my essay?
Writing an essay is a skill you practice and perfect during your time at university and there are a new set of rules, structures and guidelines to follow. Go through our section on how to write an essay to give you a few pointers on choosing your topic and how to do your research. If it's the essay topic in question that's giving you some problems, go and see your tutor and ask for some clarification. If it's a case of not having enough material or knowledge then it's off to the library to research some books.
Help! I've written too many words for my essay!
This can be quite a common problem when writing an essay, especially if you really enjoy the topic and have lots to say on it. Take a few days away from your essay once it's finished (as long as you have time before the deadline) and then come back to it with your editor's hat on. Be ruthless and make sure the essay is analytical, concise and answers the question.
Go through each paragraph and summarise the main point, support and argument sections. Then use this to spot all the unnecessary 'filling' words you've used and look out for ways to reword sentences and structure.
Help! I'm finding it hard to get up and go to lectures!
Take a minute to think about your lifestyle and whether that could be affecting your ability to get out of bed in the mornings. Make sure you get enough sleep every night. Try and establish a routine of waking up at a specific time so your body clock gets used to waking up in the mornings. The more you do it, the easier waking up and getting go will become.
Help! do I need to do the reading?
Being presented with an extensive reading list can be a bit daunting and off putting but to put it simply; yes! You should do the reading to prepare you for the seminars, exams and to further improve your knowledge. The onus is on you to get the most out of your degree and doing the reading is part of this.
It's really vital you do the reading for seminars as this is the time you participate and discuss questions and arguments about a topic. For some modules seminar participation contributes to your overall mark. If you're not sure how to read effectively or how to do it in general then look over our reading section.
Help! How do I revise?
By now, after having done your GCSE's and A-levels you should have a good idea of how you revise and what works well for you. Make sure you plan your revision and do it well in advance of your exams. Remember as well that studying a language requires revision in reading, writing, speaking and listening so don't neglect one area - they all need practice.
Draw up a revision plan and stick to it. Make sure you're realistic about when and how long you're going to revise for. Make sure you take regular breaks and focus on the quality of your revision rather than the quantity; by doing it thoroughly you're more likely to remember and retain what you've revised.
Revise in an environment that works for you. This might be the library where it's nice and quiet or in a spacious room at home with some soft music, use whichever method and place works for you.
Make sure you're getting enough relax time - sounds great, but seriously make sure you're giving your brain enough 'switch-off' time so it's capable of concentration when you need it.
Presentations are daunting especially as you could be giving them to more people than you've ever seen in one room before! Although they seem scary they're a big part of development and preparing you for the future. Make sure you've researched and know your topic well and have had plenty of practice. Look at our section on giving presentations if you need a bit more info.
Deadlines play a big part in university life and the best way to deal with them is to give yourself plenty of warning. Have a calendar of the semester on your wall at home with all your deadlines on and review it every few days so you see what's coming up and when. Use this semester plan to work out what to do to prepare for the deadline on a weekly basis, by planning your time with the deadline in mind you'll neatly approach it feeling fully prepared.
If you suddenly find out you've got a deadline you didn't know about then don't panic. Find out what you need to do for it and prioritise this above other things. Universities penalise late work so try your hardest to get it in on time. If you're not sure how best to plan your time then check our time management section.
Help! How do you learn all the language?
There's no need to worry about learning every word in the dictionary because no-one can learn all the language. Everyday almost you come across new words in your mother tongue but this doesn't impair your ability to communicate in it.
Make sure you practice your language every day and use all the resources available to make it an interesting and varied activity: such as watching authentic TV and films as well as reading the daily papers. Doing a little every day helps keep your ear tuned and your brain thinking in your foreign language.


The Union Cabinet recently in an ambitious push for clean energy, ramped up the country's solar energy generation target five times to 100 GW by 2022, from 20,000 MW under the Jawaharlal Nehru National Solar Mission (JNNUSM). This will also greatly reduce the country's reliance on fossil fuels thus reducing our carbon emissions, which is the third largest in the world behind China and United States of America. Currently, India has an installed solar photovoltaic capacity of 3,800MW.
To boost the investment in Renewable energy, Japan's SoftBank Corp. said Monday it is forming a joint venture with India's Bharti Enterprises and Taiwan's Foxconn Technology Group to invest about $20 billion in renewable energy in India. All three parties will invest in the joint venture, called SBG Cleantech Ltd., SoftBank said in a news release.
A spokesman for SoftBank said the company's chairman and chief executive, Masayoshi Son, and Bharti Chairman Sunil Bharti Mittal told a news conference in New Delhi that the joint venture would aim to generate 20 gigawatts of electricity, which would translate to around $20 billion worth of investments.
The Indian government wants the country to generate 100 gigawatts of solar power by 2022, up from around 3 gigawatts today. The SoftBank investment follows a similar announcement by India's Adani Group, which last month said it would spend 600 billion rupees ($9.45 billion) to build a 10-gigawatt solar- power plant in the western state of Rajasthan. Adani said that it would also build a solar-panel plant worth $4 billion along with SunEdison Inc.


Here are the Resident Evil 6 Endings. Resident Evil 6 spoilers ahead!
Don't worry too much if you have not finished the game yet. CNN research from Activision & Raptr showed that on average a huge 90% of gamers do not finish their games!!
To me it looks like they are dropping some heavy Resident Evil 7 Hints.
What do you think the Resident Evil 6 endings mean?


MIPS CEO Johan Thiel says 19 cycling brands use (or will soon be using) his company's safety technology (click to enlarge).
By now you've almost certainly heard about MIPS — aka multi-directional impact protection system. The Stockholm, Sweden-based company with the same name was founded in 2001 and has one product: the MIPS Brain Protection System, which separates a helmet's shell and liner with a low friction layer that's designed to reduce rotational forces on the brain caused by angled impacts to the head during a crash.
Since launch, MIPS has become ubiquitous in the cycling industry. At September's Interbike cycling industry trade show in Las Vegas, MIPS CEO Johan Thiel claimed that 19 attending companies had (or would soon have) MIPS equipped products on the market. Overall, Thiel estimates that roughly 400,000 MIPS units have already made it onto consumer heads worldwide, and that number is increasing quickly. The total number of brands from all sports segments is 44 and climbing.
Helmet makers such as Bell and Giro have been some of the most eager adapters, a fact reflected in the sheer number of MIPS equipped helmet models each company has, and that parent company BRG Sports has invested in MIPS the company. Generally speaking a MIPS-equipped helmet costs $20-$25 more than its non-MIPS equivalent.
MIPS has even found its way into kid's helmets (click to enlarge).
Thiel is undeterred by such skepticism, as we found out during a lunchtime interview with the MIPS CEO during Interbike. Here are some highlights from that conversation.
RoadBikeReview: How often do you hear from people who feel like MIPS changed the outcome of an accident for them?
Johan Thiel: Quite often actually. Just in the last three weeks I have heard from people who had sever crashes who were grateful for having the product. No we can not prove that absolutely it was MIPS that made the difference. But we know our technology works based on the tests that we have done. So it feels good to know that consumers are grateful for what we are doing. It makes a difference having a helmet and it makes a difference having a helmet with MIPS.
RBR: You have strong adoption in the bike helmet world, so what is next for MIPS?
JT: Our objective remains the same. We are looking from a science point of view on how we can save lives, specifically by protecting the head and brain. That is where we came from and that is our knowledge base. We also have other computer models such as the human neck that we are looking at. But right now our focus remains on the brain.
We are an ingredient safety company so we are always looking into other products that could help save lives. That could be indication that EPS part of a helmet is too worn out by way of installed sensors. That's probably not something you will see in the next few years. But maybe in five years. We also are looking at what we can do in other segments besides sports. That could mean things such as police, fire, and military. Electric bikes is another interesting segment. We need to look at what special needs will be there. But sports remains our mainstay right now.
RBR: What have you learned about the cycling helmet industry in general since starting your company?
JT: I think the No. 1 thing is with how the helmets are built and tested. We have found that the testing is not enough. The companies are not testing what happens in real life. You have an angle to the ground and that angle causes rotational forces and that is something that has been left out. Yes, the helmets are great and are saving people's lives, but I think the industry doesn't really know what happens when you fall. That's why we are still very much in the education process with what MIPS can do for people.
What's next in this "scientific" series, are you going to ask Michael Jordan if Air Jordans are a good sneaker? " No we can not prove that absolutely it was MIPS that made the difference." Well then stop talking!
At least get Mr. MIPS to comment on the Bicycle Helmet Safety Institute paper that was critical of his product — and a legitimate criticism it would seem. The MIPS helmets I've handled are also noticeably heavier despite having less liner and the "void", what's up with that? A bigger "lever" on my head while I'm impacting some immovable object? I think not.
These are all excellent points. Nothing can actually "prevent" concussions aside from avoiding the head-slam in the first place. MIPS technology is bogus . . . although I also had a tbi recently, I can't see myself shelling money out for this false sense of security.
The best tactic, regardless of helmet, is to avoid hitting the tarmac and slamming your head. I received a monstrous concussion this Spring in a wreck during a training ride, that took 9 months to recover from (and I'm still not 100%). I firmly believe that my helmet saved my life, but NO helmet can prevent concussion. Remember, it's the g forces of impact and the brain sloshing around in the skull. MIPs technology can't prevent that at all. The best helmet in the world can't prevent concussions. This is why people get concussions from whiplash–even when they don't hit their heads. I'm going to stick with my older Bell models . . .and try not to hit my head again.
The video seems to show the most benefit of the MIPS system in relieving impact pressure / twisting to the neck more than a benefit to the skull.
As another post indicated, the impact still would seem to shake the brain inside the skull. The helmet protects the skull from fracture. But the twisting motion of landing on the pavement and rolling or tumbling on one's head affects the neck. And who wants to survive with a broken neck. Hmmmm. This is interesting.
Incorrect. Rotational injuries are the most serious type of brain injury. So it is both neck and brain at risk from rotational forces.
I spent a night in Hospital A & E department was wearing a non MIPS mountain bike helmet, yes the helmet prevented laceration injuries to head and face but received a blow to the right temple causing concussion from polystyrene in the Helmet is too dense to put in into perspective near my home there are major road widening works with a bridge being demolished there is a 52 ton pedestrian and cyclist bridge mounted on Polystyrene to reduce weight. If a bridge can be placed on polystyrene what will it do to your head when you hit the ground hard coming off your bicycle in my case it was 24 hours being monitored for a head injury.
The MIPS will never stop a concussion, just do to the fact that the helmet still compresses the brain into the helmet, and that alone, makes this helmet no better than the rest. There is a helmet on the horizon that will mitigate all concussive forces to less than 10 G's and its coming soon!
I've had two bad bike crashes in the past eight years, and in both cases my helmet saved my head and perhaps my life. I ended up with a concussion from one of them, but the helmet took the brunt of the injury. I bought a MIPS helmet (Smith Optics Overtake MIPS) last summer. I can't imagine riding without the safest technology available.
I understand MIPS is billed as a better & safer helmet design. Last season I bought a Smith Forefront MIPS helmet. This helmet is unable to sit properly on my head, it constantly floats around in an uncontrolable manner. It has gotten worse as I used the helmet more….it is so bad now that I see it as a distraction while riding. Making my new MIPS helmet unsafe, quite ironic!
I don't think this is ready for prime time.
Also page 16-18 here, biased researcher but regardless of interpretation the numbers are most likely real.