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She-wolf (disambiguation)
She-Wolf of London
The gray wolf or grey wolf (Canis lupus), also known as the timber wolf or western wolf, is a canid native to the wilderness and remote areas of North America and Eurasia. It is the largest extant member of its family, with males averaging 43–45 kg (95–99 lb), and females 36–38.5 kg (79–85 lb). Like the red wolf, it is distinguished from other Canis species by its larger size and less pointed features, particularly on the ears and muzzle. Its winter fur is long and bushy, and predominantly a mottled gray in color, although nearly pure white, red, or brown to black also occur.As of 2005, 37 subspecies of C. lupus are recognised by MSW3.
The gray wolf is the second most specialised member of the genus Canis, after the Ethiopian wolf, as demonstrated by its morphological adaptations to hunting large prey, its more gregarious nature, and its highly advanced expressive behavior. It is nonetheless closely related enough to smaller Canis species, such as the eastern wolf,coyote and golden jackal to produce fertile hybrids. Its closest relative is the domestic dog, with which it shared a common European ancestor which likely diverged 40,000 years ago. It is the only species of Canis to have a range encompassing both the Old and New Worlds, and originated in Eurasia during the Pleistocene, colonizing North America on at least three separate occasions during the Rancholabrean. It is a social animal, travelling in nuclear families consisting of a mated pair, accompanied by the pair's adult offspring. The gray wolf is typically an apex predator throughout its range, with only humans and tigers posing a serious threat to it. It feeds primarily on large ungulates, though it also eats smaller animals, livestock, carrion, and garbage.
This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Gray_wolf
A she-wolf is a female member of the species Canis lupus. The classical Roman she-wolf icon is known as the Capitoline Wolf.
She-wolf or she wolf may also refer to:
The She-Wolf (Italian: La Lupa), an Italian verismo novella by Giovanni Verga, published in 1880
"The She-Wolf", a story by Saki
She-Wolf: The Story of a Roman Icon, a historical study of the Capitoline Wolf by Cristina Mazzoni, Cambridge University Press
She Wolf, a 2009 dance-pop album by Shakira
"She Wolf" (Shakira song), the title track from her album
"She-Wolf" (Megadeth song), a song by Megadeth
"She Wolf (Falling to Pieces)", a 2012 single by David Guetta on his album Nothing but the Beat 2.0
She-Wolf, a 1981 country blues album by Jessie Mae Hemphill
She Wolf: The Last Sentinel, a Philippine fantasy horror television series
She-Wolf (TV series), a 1990s horror fiction television series
The She Wolf (1919 film)
This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/She-wolf_(disambiguation)
She-Wolf of London was a television series produced by the Finnegan/Pinchuk Company, HTV and MCA Television Entertainment that aired in first-run syndication in the USA from October 1990 to April 1991. The first 14 episodes were filmed in England and aired under the She-Wolf title, and a second season of six episodes was filmed in Los Angeles and aired under the title Love and Curses, with a drastically reduced cast.
American grad student Randi Wallace (Kate Hodge) travels to Britain to study mythology with Prof. Ian Matheson (Neil Dickson). She arrives expecting a stodgy old academic, but Ian is young, and the two are immediately attracted to one other. Their attraction increases when complication quickly pales when Randi spends a night on the moors and is bitten by a werewolf. She survives what the local hospital thinks was an attack by a large rabid wolf. She insists it wasn't a wolf, but something supernatural seeks Ian's help after surviving a werewolf attack on the Moors. For the rest of the series, Randi and Ian investigate supernatural phenomena together while they search together for a cure, and he becomes her keeper during her transformations, under the secrecy of the Matherson House and keep away from Ian's family. Randi's curse draws the attention of various supernatural creatures: another werewolf, spirit possession, succubus, a possessed bookstore, a bogman, an evil carnival, a guy fawkes spirit, a killer horseman, in a small town, zombies who ultimately confront Randi in her werewolf form (Diane Youdale). Eventually, their search takes them from British academia to American TV, when they move back to Randi's native California, and Ian becomes host of a trashy TV talk show focusing on psychic phenomena. The series was an old-style romantic comedy with a touch of horror. The romantic comedy comes from Randi and Ian's relationship between each other and the Matheson family, plus people Ian work for.
This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/She-Wolf_of_London


Here at Queensway Optometric Centre, we understand the importance of your vision. Clear sight helps you live your life to the fullest and enjoy every moment. Our team of experts has been serving families in Mississauga for over 50 years, and remain committed to helping you keep your eyes healthy and your vision clear.
We are proud to offer exceptional eye care for the whole family, and always strive to meet your vision care needs in a welcoming and family-friendly environment. We also understand that families are busy, so we are pleased to offer extended hours Monday through Thursday and select Saturdays, making it easier to schedule appointments for you and your family.


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Republicans Focus on Terrorism, Democrats on Gun Control After San Bernardino Shooting
Republican Presidential hopeful Ted Cruz of Texas arrives to speak during the Republican Jewish Coalition Presidential Forum in Washington, DC, Dec. 3, 2015. (Credit: AUL LOEB/AFP/Getty Images)
On the presidential campaign trail, in the White House and on Twitter, it was as though politicians were responding to completely different events.
After the shooting rampage in San Bernardino, Democrats forcefully demanded a tightening of the country's gun laws, laying blame on a culture that allows even people who are not permitted to board airplanes to buy guns with ease. Republicans talked of an entirely separate policy failure, drawing on news reports that the massacre may have been spurred by religious extremists to warn that the country is under attack and ill-equipped to deal with it.
The starkly disparate takeaways from the rampage showed the distance between the two parties on an issue that has become increasingly vital to Americans: their personal safety in the face of mass violence and terror. The rampage put presidential candidates in a quandary on a day when almost all of them were holding public events and found themselves under pressure to address the violence in California, even as the facts remained murky.
As more details about the attackers were made public through the day, GOP candidates — nearly all of whom spoke at a Washington forum hosted by the hawkish Republican Jewish Coalition — issued increasingly harsher attacks on what they said was the Obama administration's unwillingness to come to terms with the true threat posed by Muslim extremists.
Click here to read the full story on LATimes.com.

redpajama_set_name: RedPajamaCommonCrawl


Flower Delivery Chicago - Chicago Florist - The Bouqs Co.
Farm fresh bouquets freshly cut and shipped directly from our eco-friendly farms all over the world to Chicago! We stand by our stems with our 100% Happiness Guarantee.
With millions of people and a long, tough winter, Chicago knows how to do Spring and Summer right, and The Bouqs Company is your favorite florist of choice. Bouqs delivers artisan florist and farm fresh flowers across the greater Chicago area, to bring a bit of color and freshness to the Windy City. From Birthdays to Anniversaries to Mother's Day and Valentine's Day, The Bouqs Company has Chicago covered as your favorite local florist.
Bouqs sources only the best sustainable blooms from around the country and the world, to deliver to Uptown, The Loop, Lincoln Park, River North, Wicker Park, Bucktown and more. Hydrangea, lilies, gerber daisies, roses, tulips and peonies are some of Chicago's favorite blooms, and The Bouqs Company brings a wide selection of type and color to the city on a daily basis.
You might be buying a gift for a friend, a relative, or a colleague, The Bouqs Company has you covered in Chicago. Consider a throwback old school red rose bouquet, or mix it up with a farmer's choice bouquet, or consider something exotic like multicolor carnations or a tropical bouquet. We ship only the highest quality, sustainable and eco-friendly flowers, and we deliver across the entire Chicago metro area. By cutting out the middle man we deliver only the freshest and most sustainable blooms, and that's what sets Bouqs apart.


In the paper manufacturing process, the filter and press water is extracted from the fibrous water suspension in the paper machine. There are various levels of retention which depend on the type of paper being manufactured and the composition of the suspension. The retention indicates the proportion of the fibrous filling substances left in the filter compared to the complete retention of the substances in the waste water.
In the manufacture of hygienic tissues, such as toilet paper, tissues or facial tissues, a lot of fibrous substances remain in the water from filtering and pressing the fibrous water suspension.
This water is treated in the in-house waste water facility. The solids are concentrated before being removed from the water in a filter belt press. To transfer the water with all the solids into the filter press, a Boerger Rotary Lobe Pump is used at the paper factory in West Germany.


The red carpet was opened to Hawaii Five-0 fans this weekend, as filming for the second season wrapped up. This decidedly non-networking event was more of a thank you to viewers from one of the islands' favorite on-screen personalities.
Taylor Wily gives his fans true star treatment on the red carpet.
Taylor Wily plays shave ice and shrimp truck entrepreneur Kamekona in a recurring role on the CBS television series. Unlike others on the show, he needed no coaching in the local pidgin dialect. Born in a small town on the north coast of Oahu, he's as local as they come. Although he now appears in front of the cameras, Taylor says he was always a fan of the original show. "I was born into the Hawaii Five-0 ohana," he said. Ohana is usually translated as "family," but the Hawaiian word means much more than the traditional nuclear family. It often includes those connected by love or friendship, as well as genetics. For a few hours Saturday evening, Taylor embraced his Hawaii Five-0 ohana with opened arms.
The evening turned the tables on the traditional network premiere, putting fans on the red carpet and allowing them virtually unlimited access to Taylor. He posed with everyone who entered, autographed anything presented and answered questions for anyone who asked. Before this weekend, some local fans knew one another only through blogs or social media. This was a chance for them to meet for the first time. Some had acted in an episode or more of the show. A few traveled from the mainland just for this event. Others were old friends, or friends of the local organizers. They took photos with Taylor, chatted with one another, enjoyed musical performances and a beautiful (if occasionally misty) evening at Aloha Tower in Honolulu — all while sharing their favorite Hawaii Five-0 stories.
" Five-0 Redux" blogger Wendie Burbridge (left, in red) mingling with other Wrap'Um attendees.
An aside: organizers kept a wary eye on the skies, concerned that the mist and occasional drizzle might turn into actual rain. Three of the mainland visitors came from Arizona and California. One of them said, "It was 100 degrees today in Phoenix, so we just got on a plane and came." It is so easy to forget that even what we consider poor weather here is only slightly less than perfect to people from mainland states.
The event had been put together through a community effort of bloggers, photographers, comedians and performers. Bruce and Yaling Fisher of Hawaii Aloha Travel (HAT) did a very fine job as well in orchestrating a memorable night for Five-0 fans. And in the true spirit of aloha, everyone was welcomed to the party to celebrate one of Hawaii's favorite shows and beloved sons, Taylor Wily.
(Top) Bruce Fisher with our fans visiting from the mainland. (Bottom) Yaling Fisher being her funny self.


Markets might have had a slow start to the week, but that quickly changed on Tuesday. After US CPI came out in line with expectations, US President Donald Trump dropped a bit of a bombshell on markets by firing Secretary of State Rex Tillerson.
The USD didn't respond all that well to the move and fell away over the course of the US session.
That meant there was a bit of upside in some of the majors such as the EUR/USD and GBP/USD.
There's more big data scheduled for Wednesday with most of the focus on US retail sales.
There is some degree of support in the DXY sitting at 89.50. But having a closer look at the charts, it looks a lot like a head and shoulders pattern is forming.
That's a bearish sign for the USD, which only last week started to find some buying interest.
However, the price action appears to be bearish in the short-term so I suspect we might be set for a breakout below support. That means we could be setting up for another crack at 88.50 which would mean the majors could see some upside against the USD.


When somebody important to us dies, there are many things that need to be done and organised. Whilst standing close to a death, grief seems like an large tree and overshadows everything. Be assured that as you move on you will look back and see a whole life in a better perspective and you will know that your life has been enriched because for some part of the journey you walked with this person.
Both Churches are filled with natural light and are the right choice for many as a place to say goodbye to people, who are special to us, who have died and to commend them to the eternal care of God. We can comfortably sit groups up to about 150 people in the Church Building.
We will want to spend some time thinking back on the life of our friend.
We will want to spend some time reminding ourselves of the sure and certain hope of the resurrection from the dead through Jesus Christ our Lord.
We will commend our loved one to God, and pray for strength for ourselves and each other and commit ourselves to care for those closest in kindred and affection.
And we will say goodbye to the body as the earthly remains that while here was our encounter with this person.
In short at the Funeral we will look back and give thanks, we will look forward and pray for strength, and we will look up to God in whom all things both begin and end.


The North West Warriors were first formed back in 1996. Being situated in the Lake District, there was a distinct lack of organisation enabling wargamers to come together to participate in their favourite activity (...), so we took it upon ourselves to travel the country and participate in tournaments. It was at these tournaments that we met more like-minded individuals, and the club began to grow.
Over time, the NWW group began to think about running their own tournaments and so "A Gathering of Might" was born.
AGOM XXII & XXIII tickets are available now!


The aim of this study was to investigate the potential protective effect of Lycium barbarum polysaccharides (LBP) pretreatment against cadmium (Cd)-induced hepatotoxicity in rats. Wistar rats were divided into control group, LBP group (300 mg/kg orally, once a day, for 30 days), Cd group (CdCl2 4 mg/kg i.p. once), and LBP + Cd group (LBP 300 mg/kg orally, once a day, for 30 days + CdCl2 4 mg/kg i.p. 24 h after the last treatment). Cd liver injury was examined by morphological/histological changes, transaminases, total protein concentration, and oxidative stress evaluated by MDA, 3NT, GSH, SOD, and TEAC activities. Cd intoxication caused gross morphological changes with hyperemia of the parenchyma, increased volume, and disappearance of the anatomical limits of the lobes associated with an increase of ALT, GSH, and TEAC in plasma and a decrease of MDA, GSH, and TEAC in liver, SOD, and total proteins in plasma. LBP pretreatment caused a slight improvement in the histological architecture and in the 3NT amount together with a significant improvement of hematic parameters. On the basis of the obtained results, we can affirm that LBP pretreatment can ameliorate liver conditions, but further studies are needed to better evaluate the protective antioxidant effects of LBP against Cd-induced toxicity.
In this research, multiwall carbon nanotube was magnetized and subsequently functionalized by thiosemicarbazide. After characterization by FTIR, BET, SEM, EDAX, and VSM techniques, the magnetized adsorbent (multi-walled carbon nanotubes (MWCNTs)/Fe3O4) was used for removal of Hg2+ from aqueous solutions and the experimental conditions were optimized. The adsorption capacity of 172.83 mg g−1 was obtained at 25 °C and pH = 3 which was superior to the value obtained for initial multiwall carbon nanotube, magnetized sample, and many previously reported values. In the presence of Pb+2 and Cd+2, the adsorbent was selective towards mercury when their concentration was respectively below 50 and 100 mg L−1. The adsorption process was kinetically fast and the equilibration was attained within 60 min with 69.5% of the capacity obtained within 10 min. The used adsorbent was regenerated by HNO3 solution, and the regenerated adsorbent retained 92% of its initial capacity. The magnetic sensitivity of the adsorbent allowed the simple separation of the used adsorbent from the solution by implying an appropriate external magnetic field. The adsorption data was well fitted to the Langmuir isotherm model, indicating homogeneous and monolayer adsorption of mercury by the adsorbent.


text:
Accumulation rates of spiral-like structures in fluid flows
R.M. Everson, Katepalli Sreenivasan
Center for Space Science
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
Everson, R. M., & Sreenivasan, K. (1992). Accumulation rates of spiral-like structures in fluid flows. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 437(1900), 391-401.
Accumulation rates of spiral-like structures in fluid flows. / Everson, R.M.; Sreenivasan, Katepalli.
In: Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, Vol. 437, No. 1900, 08.05.1992, p. 391-401.
Everson, RM & Sreenivasan, K 1992, 'Accumulation rates of spiral-like structures in fluid flows', Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, vol. 437, no. 1900, pp. 391-401.
Everson RM, Sreenivasan K. Accumulation rates of spiral-like structures in fluid flows. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. 1992 May 8;437(1900):391-401.
Everson, R.M. ; Sreenivasan, Katepalli. / Accumulation rates of spiral-like structures in fluid flows. In: Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. 1992 ; Vol. 437, No. 1900. pp. 391-401.
@article{fb978abe635647d88bf7d8cdfe884020,
title = "Accumulation rates of spiral-like structures in fluid flows",
author = "R.M. Everson and Katepalli Sreenivasan",
journal = "Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences",
publisher = "Royal Society of London",
number = "1900",
T1 - Accumulation rates of spiral-like structures in fluid flows
AU - Everson, R.M.
AU - Sreenivasan, Katepalli
JO - Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
JF - Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
IS - 1900


Did you catch the article about us and owner Brandi Dice in the Spartanburg Herald Journal? Click on the button and check it out!
This Art Walk will be a demo night! Multiple artists from different art disciplines will be at The Art Lounge showing off how they create their art! This event will be on July 20th from 6 pm to 9 pm. Come and join us!
There will be painting, metal work, glass blowing, jewelry making and much more!
We have a food truck! Herb N Eats will be serving food for the Demo Night!
Join us on August 17th for a jewelry show by custom jewelry and design artist Melinda Ledford Crowe! Show will last from 6pm to 9pm!
Tiny Pieces, Tiny Prices is an art sale that will be held at The Art Lounge on May 18th! All pieces are under $100!


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Q: Numpy Concatenate Images into Array I have a bunch of images that I want to store into an array.
The problem is that all my images are different sizes and I don't want to necessarily change their size, because some will be square and some aren't.
I tried using np.concatenate but someone online said it was better to construct a zero matrix and fill it.
However, using
image = misc.imread(filename)

from the scipy library. The image is returned as a 3 dimensional array. How should I construct my numpy ndarray if I want to store all the images in it?

A: If I'm understanding the question correctly, you are trying to store a bunch of images of different sizes that are each stored as separate numpy arrays. If your images are gray scale (meaning 2D, as opposed to RGB which are 3D - a channel for R, G and B), you could store the images as the third dimension, filling in the absent pixels with 0s. But the best way would be to just use a python list (or tupple maybe) that stores a list of your numpy array images. That way they can be different sizes. i.e.: img_list = img1, img2, img3, etc.

A: storing them in a list may be easier, the list will store them as array() objects and size wont matter, when you do operations on them, just reference the list elements.

redpajama_set_name: RedPajamaStackExchange


WALE! – Jonez, Where We Going?
Even though I am a Baltimore Chick through and through, I Love Wale!! I know I know, he's from DC and this is a forbidden love, but I can't help it. There's something about him musically that I can not get enough of. It's like he knows everything about me so he writes songs that speaks directly to me. There hasn't been an album released by my boo Wale that I didn't love and rock until I couldn't listen anymore.
I'm currently obsessing over his latest release, SHINE. I believe this is his best work to date. However I always feel like he continuously pushes himself, with each album release. I love that he has incorporated more of the sounds from his country, although he does have more features this time around. I honestly couldn't pick my top three but I forced myself to do so.
Top Three: My Love, Fashion Week and My PYT … honorable mention CC White.
SideNote: Wale's Summer on Sunset (Mixtape) is Fire. It's unfortunate that I haven't been able to put the album on my phone and Spotify is not up on game. If you get the chance to listen to the album, Please listen to Day by the pool, its ridiculously sick!


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For those planning a vacation to the beach this summer it is important to realize the dangers of rip currents before going into the ocean. The following are important things you should know about rip tides and rip currents before going in the ocean. This year Rip Tide Awareness Week runs from June 4-10, 2018.
Following is information about rip tides and currents from the NOAA website. Educate yourself now about what to do if you or a family member finds yourself caught up in a rip current so you'll be able to get yourself or others out of it.
Rip tides and currents are powerful currents of water that are moving away from shore in a forceful manner. They are the greatest surf hazard for all beachgoers of all levels, especially for non-swimmers. According to the United States Lifesaving Association, 80 percent of surf beach rescues are due to rip currents. More than 100 people die every year from drowning when they get caught up in a rip current and are unable to free themselves.
Rip tides and currents occur when waves break near the shoreline, piling up water between the breaking waves at the beach. One of the ways this water returns to sea is to form a narrow jet of water that moves swiftly offshore, roughly perpendicular to the shoreline. This is called a rip tide or rip current.
Under most tide and sea conditions the speeds are relatively slow, however when wave, tide and beach conditions align, the speeds can quickly increase to become dangerous to anyone entering the surf, even the most experienced swimmers.
Rip currents can be very narrow or extend in widths to hundreds of yards. The outward pull of rip currents varies from just beyond the line of breaking waves to hundreds of yards offshore.
– or a break in the incoming wave pattern.
Rip currents are often not readily or easily identifiable to the occasional vacationer. If you are concerned about the possibilities of rip currents occurring in the surf, it is best to ask a lifeguard before entering the water.
If you are caught in a rip current, stay calm, conserve energy and think clearly. Never fight against the current. Swim or move yourself in a direction parallel to the shoreline. When out of the current, swim at an angle away from the current and toward the shore. If you are unable to swim out of the rip current, float or calmly tread water. When out of the current, swim toward shore. If you are unable to reach shore, draw attention to yourself by waving your arms and calling for help.
If you see someone in trouble, don't become a victim yourself. Many people drown each summer while trying to save someone else from a rip current. Get help from a lifeguard if one is available. If not, have someone call 911. Throw the rip current victim something that floats such as a life jacket, cooler or inflatable ball.
It is important to note that rip currents can occur under any conditions and beachgoers should know how to swim and listen to the advice of beach patrol before entering the surf. When areas of rip currents are marked with signs, respect the signage and avoid the area.


text:
$LOAD_PATH << Rails.root.join("tools").to_s

require "miq_config_sssd_ldap"

describe MiqConfigSssdLdap::ConfigureSELinux do
  describe '#configure' do
    before do
      @initial_settings = {:ldapport => '22'}
      @success = double(:command_line => "semanage", :failure? => false)
      @semanage_params = {nil => "port", :a => nil, :t => "ldap_port_t", :p => %w[tcp 22]}
      @failure1 = double(:command_line => "semanage", :failure? => true, :error => "malfunction already defined")
      @failure2 = double(:command_line => "semanage", :failure? => true, :error => "malfunction")
    end

    it 'invokes semanage and setsebool with valid parameters' do
      expect(AwesomeSpawn).to receive(:run).once.with("semanage", :params => @semanage_params).and_return(@success)
      expect(AwesomeSpawn).to receive(:run).once.with("setsebool", :params => {:P=>%w[allow_httpd_mod_auth_pam on]}).and_return(@success)
      expect(AwesomeSpawn).to receive(:run).once.with("setsebool", :params => {:P=>%w[httpd_dbus_sssd on]}).and_return(@success)
      expect { described_class.new(@initial_settings).configure }.to_not raise_error
    end

    it 'handles semanage already defined result' do
      expect(MiqConfigSssdLdap::LOGGER).to_not receive(:fatal)
      expect(AwesomeSpawn).to receive(:run).once.and_return(@failure1)
      expect(AwesomeSpawn).to receive(:run).once.with("setsebool", :params => {:P=>%w[allow_httpd_mod_auth_pam on]}).and_return(@success)
      expect(AwesomeSpawn).to receive(:run).once.with("setsebool", :params => {:P=>%w[httpd_dbus_sssd on]}).and_return(@success)
      expect { described_class.new(@initial_settings).configure }.to_not raise_error
    end

    it 'handles semanage failures' do
      expect(MiqConfigSssdLdap::LOGGER).to receive(:fatal).with("semanage failed with: malfunction")
      expect(AwesomeSpawn).to receive(:run).and_return(@failure2)
      expect { described_class.new(@initial_settings).configure }.to raise_error(MiqConfigSssdLdap::ConfigureSELinuxError)
    end

    it 'handles setsebool failures' do
      expect(MiqConfigSssdLdap::LOGGER).to receive(:fatal).with("setsebool failed with: malfunction")
      expect(AwesomeSpawn).to receive(:run).once.with("semanage", :params => @semanage_params).and_return(@success)

      expect(AwesomeSpawn).to receive(:run)
        .and_return(double(:command_line => "setsebool", :failure? => true, :error => "malfunction"))
      expect { described_class.new(@initial_settings).configure }.to raise_error(MiqConfigSssdLdap::ConfigureSELinuxError)
    end
  end
end

redpajama_set_name: RedPajamaGithub


What are Blue Buffalo Stix Dog Treats?
Blue Buffalo Stix Dog treats are moist meaty treats with a delicious flavor dogs love. These tasty lamb flavored treats contain all natural ingredients and absolutely zero artificial preservatives or flavors, corn, wheat, or soy, or chicken/poultry by-product meals. Blue Buffalo Stix are perfect as a healthy treat to reward your dog's good behavior.
How do Blue Buffalo Stix Dog Treats work?
These moist, meaty dog treats give your dog a tasty treat that is also good for him or her without the unhealthy ingredients typically found in traditional dog treats.
Blue Stix are intended for intermittent or supplemental feeding only.
Give as a treat as a supplement to regular food.
Ingredients: Lamb, Chicken Meal, Oatmeal, Potatoes, Vegetable Glycerin, Gelatin, Sugar, Maple Sugar, Dried Beet Pulp, Brown Rice, Sweet Potatoes, Natural Flavor, Flaxseed, Salt, Natural Smoke Flavor, Dried Cultred Skim Milk, Blueberries, Carrots, Apple, preserved with Lactic Acid, Citric Acid and Mixed Tocopherols, Oil of Rosemary.


text:
Features / Health & Wellbeing
Lego-based play therapy could help children with autism develop social skills
By Jane Kirby
February 25, 2017, 9:05 am Updated: February 25, 2017, 9:28 am
Lego (Getty Images)
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EXPERTS are looking to play therapy using Lego to help children with autism develop their social skills.
A new study at the University of York will use Lego in small groups to help children with autism refine interaction skills and express themselves through play.
Lego-based therapies were developed in America but are now used around the world as a recognised practice.
It's estimated that about one in every 100 people in the UK has autism, and currently, more boys are diagnosed with the condition than girls are.
Professor Barry Wright, from York's Department of Health Sciences, and director of its new child mental health centre, said: "Previous pilot work has shown that many children with autism spectrum disorders (ASD), both boys and girls, engage with Lego.
"They enjoy the sensory aspects of Lego and also the geometric patterns and the engineering involved in building models.
"They also like the process of construction. Research shows that children with ASD are not asocial — they do not wish to completely avoid social interaction.
"Children with ASD are 'differently' social, preferring to engage socially with others in much smaller groups than neurotypically developing children, and it's usually based around common interests.
"They are much more likely to engage in interactions and conversations that are factually, practically or technologically-based, rather than conversations about feelings or social relationships.
"Lego-based therapy can help children with ASD develop co-operative and interactive skills around mutually-enjoyable play."
The Lego study is being funded by the National Institute for Health Research (NIHR).
Another study at the centre, funded by the Medical Research Council, will specifically look at the ways deaf children are being diagnosed with autism.
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First game for season 2018/2019 for Series Futsal Victoria Womens league. Carlton take on Pascoe vale both teams looking to start their season with a win.
Carlton get the first goal for the same three minutes in. Pascoe vale continue to press hard and create scoring opportunities. They struggle to find the back of the net.
With both keepers kept busy and the ball being turned over constantly it made for an interesting game. Both clubs pushing hard and having shots they both struggle to get reward for effort.
Finally after continues shots on goal Carlton able to score their second goal for the half. Going into half time with a 2-nil lead.
Second half resumes and both teams come out firing. Pascoe searching for their first goal and Carlton searching for their third. Neither team able to have shots on target. With multiple shots going either over the net or straight to the keeper.
Two players receiving yellow card brining the intensity of the game higher and more exciting. With four minutes remaining in the half and still no goal scored in this half.
With two minutes remaining Carlton able to find their third goal. Seeing them win 3-nil.
Fitzroy looking to start this season the way they left the last with a win over the new comers Northcote.
Fitzroy get the first two goals for the game, really putting the pressure on the new comers. But Northcote dig deep and don't let the lead phase them. Going on to score themselves, their first goal for the season.
Fitzroy hit back and score another 2 goals to extend their lead and give them a 3 goal advantage. Fitzroy's pressure allows them to have control of the ball and have majority of the possession in their forward half.
Fitzroy really getting a spread of goal kickers in this first half. With all five goals scored from five different players. A solid team effort.
With four minutes in the half remaining Dharma Georgi able to score her second goal for Fitzroy.
Second half under way and Northcote reply quickly with a quick goal. Helping them keep motivation to stay in the game and reduce the 5 goal lead. Emily Coppock replies quickly for Fitzroy to score her third goal.
Fitzroy extend their lead out to nine goal lead. With eight minutes remaining Fitzroy making it to hard for Northcote to come back from.
With 40 seconds remaining Fitzroy score their 16th goal for the game.
Westside new comers to Series Futsal really put it up to Moreland in the first half.
Westside able to get the first goal of the game to start their season on a good note. Moreland needed a quick reply and they got it. Game level anyone game early in the first half.
Westside respond and go on to score two quick goals with eight minutes remaining in the first half. Moreland able to find their second goal in the first half to reduce the lead back to one goal. With the ball constantly getting turned over a very intense game to end the first round.
At half time Westside lead 3-2.
Westside come back firing in the second half. Getting two quick goals five minutes into the first half. To extend their lead out to three goals. Making it harder for Moreland to come back from.
Moreland able to score their third for the game but in west side style. They reply with a quick goal. To keep their three goal lead. Both keepers were kept busy late in that second half. Westside come away with their first win for the season.


Last week, the European network of International Financial Institutions (EuroIFInet) watchers met in Brussels for their biannual strategy meeting. The meeting offered the chance for representatives from 20 European non-governmental organisations (NGOs) to share information updates and to coordinate actions ahead of the World Bank and International Monetary Fund (IMF) spring meetings, which are due to take place from 19 to 21 April 2013 in Washington, DC.
This year, Eurodad hosted the meeting of this informal but active network of NGOs together with the Belgian-based National Centre for Cooperation and Development (CNCD). Two participants from the global south, Aly Sagne from Senegal (Civil Society Coalition on the African Development Bank) and Sukhgerel Dugersuren from Mongolia (OT Watch) shared their experiences with European colleagues.
The network discussed the ongoing review of the World Bank's environmental and social safeguards policies, as well as its implications for specific sectors such as procurement, land tenure and the environment. Several sessions revolved in particular around the reaction of civil society organisations (CSOs) to a recent audit on the environmental and social impacts of financial investments through the International Finance Corporation – the World Bank's private sector lending arm.
Issues related to the private sector were also addressed during the meeting through discussions about CSO concerns regarding the World Bank's Doing Business Review and regarding the operations of the European Investment Bank and the European Bank for Reconstruction and Development, including in the energy sector.
These issues will be among the topics discussed during official sessions of the World Bank and IMF spring meetings and the corresponding back-to-back Civil Society Policy Forum, which will take place between 17 and 20 April 2013.


text:
Don't Look Up's Gorilla In the Room
on January 6, 2022 January 9, 2022 By Gallant Gold Media
Every exceptional film deserves an afterthought once all the reviews have been written. Especially a film as controversial as Don't Look Up with its thousand pound gorilla in the room, busy lumbering about, pounding on its chest, bashing into walls, throwing fits from time to time, and erupting right in front of our faces. You spotted the gorilla moving from scene to scene along with the exaggerated subliminal advertisements promoting biodiversity didn't you?
If we use the size of the magnified subliminal messages as the scale by which Adam McKay (writer, producer and director) overemphasized his BOLD FACE apocalyptic warning about the dire consequences of not acting on climate change, it's unfathomable that anyone could actually not feel motivated to act. Doing nothing after watching Don't Look Up would be mind-blowing. In fact, it's inconceivable that anyone could possibly log off Netflix without making a personal commitment to vote for climate candidates in 2022 election, buy an EV, call for a solar quote, finally begin composting, plant a pollinator garden, become mostly vegan, etc. McKay deftly revealed what all human beings perishing would look like if we did nothing. Clearly McKay's ingenious experiment would prove the psychological phenomenon of Inattentional Blindness wrong, right?
Back in 1999, "The Invisible Gorilla Test" was conducted by Daniel Simons and Christopher Chabris (Simons & Chabris, 1999). Participants in a study were asked to watch a video of two teams passing basketballs. One team wore white, the other team wore black. Participants were instructed to count the number of times the white team passed the basketball. A person wearing a gorilla costume walked through the players while the teams were following through with their instructions. When participants were asked whether they saw anything out of the ordinary in the video, nearly 50 percent confirmed they had not.
Psychologists referred to this psychological phenomenon of not seeing the clearly visible gorilla in the room as inattentional blindness (also known as perceptual blindness). The participants in the study who didn't see the gorilla were focused on something else, and thus oblivious to what others considered very obvious. Again, this is a very real psychological phenomenon. Psychologists warn of the danger in perceptual blindness and cite examples of car crashes, airplane accidents, tripping and falling while walking on a sidewalk, etc.
So, to all the negative reviewers of Don't Look Up who are in the mainstream media, you were tagged by psychologists a few decades ago. The results of the 1999 invisible gorilla test were used to warn about the danger of perceptual blindness, both the danger to the distracted and the danger to others. The invisible gorilla test has been very useful in getting laws passed, especially laws about holding a cellphone while driving (1.6 million crashes each year from drivers using a cell while behind the wheel). The fact that Don't Look Up has in effect proven that it's the mainstream media that suffers from this blindness (as revealed in their bitterly defensive reviews) has to be noted so the danger can be contained.
Adam McKay's most ingenious spoof, though, was his clever play on James Vicary's subliminal messaging that Vicary inserted into a movie back in 1957 when he used .003 second flashes of "Eat Popcorn" and "Drink Coca-Cola" to inspire movie-goers to spend money on concessions. McKay's biodiversity flashes were closer to 3 seconds, so there was actually nothing subliminal about them. (Did Inception spring to mind for anyone else while watching the biodiversity hints? Not only did Leonardo DiCaprio's brilliant performance in Inception flash before my eyes while absorbing these images, but also DiCaprio being the powerful voice that promotes rewilding.) Psychological tricks really work.
The biodiversity lightbulb should have gone off for all of us. But did it?
These are just a few of the multiple unusual twists that tie-in to Don't Look Up that make the film seem prophetic rather than an instrument to inspire a rebellion against such a bleak prophecy. But do any of us want Don't Look Up to be prophetic? I'm sure billions of us don't.
The irony of McKay including a real invisible gorilla in the film isn't lost on me.
Emotions ran wild on Twitter the week following Don't Look Up's debut on Netflix with it trending for several days and the hashtag still having strong daily numbers nearly two weeks later. Fossil fuel advocates were clearly behind all the negativity.
As if to prove the point that no one listens to calm, factual statements about climate, DiCaprio appeared in a powerful YouTube video that explained the film. DiCaprio's direct, eloquent summation was the antithesis of Don't Look Up's satirical parody. Same urgent message, spoken by the same person, but two completely different styles, as if to prove why McKay went out on a limb to use a chest-pounding, screaming scientist to get the point across.https://youtu.be/YEMaLsPTWlo
McKay talks about Don't Look Up's three endings, but aren't there really four? I view the many mainstream media attacks and lackluster reviews of Don't Look Up as the fourth ending. Very similar to psych thriller Shutter Island's twisted ending when we're forced to come to grips with our altered reality.
It's time to recognize that many in the mainstream media, along with the fossil fuel industry, are the metaphorical Shutter Island criminally insane psych patient. If Adam McKay's magnified gorilla didn't change the hearts and minds of the perceptually blind, then nothing will, except perhaps laws that force them to report daily about the crisis.
John Doerr noted in his book, Speed & Scale, An Action Plan for Solving Our Climate Crisis Now, that there is no margin for error. We're out of time and can't make any mistakes. Climate is not going to get better anytime soon, it's only going to get worse. We can't pin our carbon cutting targets on false hopes. The mainstream media has just proven through McKay's incredible psychological experiment, what the obstacle is to our achieving our target of staying below 1.5ºC. The vast majority in the mainstream media will not help us in our mission to cut carbon 50 percent by 2030. Rather, they will thwart every effort that we make. So our next step has to be to create a pathway around this obstacle so we can reach our goal and save humanity.
Groundbreaking YA book series for all ages. Gripping modern day nail-biter with Machiavellian villains, but also a tale that opens our eyes to the brutal war going on beneath our feet that controls our destiny, despite our obliviousness to this potentially civilization-destroying threat.
Posted InBiodiversity,, Climate Action, Climate Change, Environment
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I love how God works sometimes. He even has plans for our gifts, and how we will use them.
Honestly, for me, as a writer, when a message starts in my head, I always get it in bits and pieces, sort of a parable to my soul.
I was driving home from work and pictured the fish in my backyard pond…and that is where it began.
These are statements made by Beth Moore this morning on Life Today.
She has had a history of pain her life, just like you and I, but the message came straight from God's heart; He wants us to know HE has a purpose for all of us.
No matter what we have been through!
Now, let's go back to my fish pond.
For months here in FL, we have a had a serious drought, to the point you could walk clear across the dry lake beds.
Our pond looked the same.
At one point we had 30 some fish that lived there, and slowly the birds came, and the dryness became the death of the little ones.
One day, I was walking on top of the deck and peered into the dry pond; there was still water, but maybe 2 inches all together.
I got the skimmer, and put it in the water from underneath the fish, and suddenly, " Splash" the fish jumped to life!
This poor fish, had barely any life left in him, he had hardly any water for oxygen, it only half covered him, and he had nothing to eat.
I went to the side of the house and immediatly began filling the pond again.
For months, the poor thing was laying in there, and if I was that fish, I have to tell you, I don't know if I would have been able to survive waiting so long for help.
I fed the fish, and the water came to a good point, and my father fixed the liner the next weekend. The fish was alive, and loving life!
We got more fish from the store, and were pretty hesitant after what happened with the first batch, but decided it would be worth another try.
From the first time we put the new fish in the pond, I noticed how the old fish reacted.
Immediatly, that fish taught them something he was forced to learn on his own…how to survive.
Whenever I go outside, I can tell you that those little fish do nothing, without making sure that big fish is at their side!
We all go through things in our life, but there really is a purpose for it.
I have a friend that knows me better than anyone, and whenever I would go through something, I would apologize for not being more with it.
When you first ever go to a counselor, like I have, or first speak of your pain, my counselor described it as opening a container in the refrigerator that has been there for ten years!
Wow, I would not want to even take a breath of how bad the odor would be lol.
Still, you have to open it, you have to begin to admit that you are desperate for change in your life, and eventually the stench of your past will disappear.
Not completely, but enough to know that you were given the life you have for a reason, and it is for a greater purpose then maybe where you stand right now.
We have to keep in our minds daily with whatever we go through that we will indeed come out of it, and we will GROW!
Do all you can your life to take your next breath!
Mmmm…..so glad that we will 'come out of it (our wilderness)' in Jesus Name!
Cracking up that you saved the goldfish – but I love it.
And I love your simple focused heart of praise towards Him. Bless you sister.
Hey!! Thank you for your sweet comment on my blog. Sorry I am just now getting back to you…but it's been a bit crazy!
Anyhooo, love the blog…love you too…sure hope you're having fun!
Loved your post. It was very encouraging. I love how God speaks to us through personal circumstances–like the parables Jesus told His disciples. God speaks in those personal sitations in our lives so we understand Him. He is so awesome!


text:
Q: Issues with mouse event I have a 3d shape. Now the shape is rotating with click event. For example, if i drag the shape to left or to right, the shape is rotating. But the issue is when i try to rotate the shape in the next way:
I click on shape, try to rotate to left and i go outside the borders of the shape, after that i let the click up. Then when i go over the shape, the shape also is rotating in different dirrections. Probably it hapens because:

 const stopRotate = () => {
    setStartX(null);
  };

actions only when i use onMouseUp on the shape, but if i go outside the shape with cursor, appears the issue above.
How to solve the problem?
Demo:  https://codesandbox.io/s/blissful-tesla-71sg2?file=/src/App.js:374-427

A: You are listening for the mouseup event on your cube. When you rotate it and the mouse goes past the shape, that event never triggers because you are not over the shape anymore.
What you should do instead is to listen for the mousedown event on the element and listen for the mouseup event on the window or body element. That way it will fire even if you are no longer over the cube.
Here is my implementation using the useEffect hook:
https://codesandbox.io/s/recursing-dewdney-jdrfu?file=/src/App.js
Note: This example is quite simple in its implementation as you may not want to trigger the stopRotate function on every mouseUp event. If such was the case, you could dynamically add the window event listener on mousedown and remove it on mouseup.


Fine and comfortable blue check viscose blend dress designed by Elsy, from the new Fall Winter 2018/2019 Collection - Baby and Little Girl clothing line. The Elsy brand realizes refined clothing for girls and fashion accessories inspired by sartorial, which express aesthetic sobriety, creative spirit and irresistibly glamorous attitude. Because of their versatility, they adapt naturally to all occasions, from the most important to the least demanding. This exclusive dress, from the A / W GIRLS Collection, is made of a viscose blend, an artificial fiber of natural origin that is particularly soft and velvety to the touch. Details: medium length with flared skirt at the bottom, classic round neckline, three-quarter sleeves with bell-shaped hem, practical zip opening at the back, pleated skirt, blue monochrome surface with all-over checked pattern and elegant decorative bow applied on one side. The Elsy dress is available for girls in the sizes New Born, Baby and Junior, from 12 months to 7 years.


text:
Speaking of Glenn Spagnuolo's best bud Ward Churchill, he'll be at the 15th (and last) Indigenous Nations and Dakota Studies conference at Southwest Minnesota State University April 2-4 to speak, shockingly, on "genocide." Organized by veteran Chutch defender and ethnic studies prof Chris Mato Nunpa, this year's conference will be on "Dakota People, Minnesota History on the Sesquicentennial: 150 Years of Lies" (grammatical as usual). Good hunk:
Even though some have called Churchill a fraud, Mato Nunpa said he has used a lot of Churchill's articles in his classes, adding that he's checked the sources.
"They're right on, they're solid work," Mato Nunpa said.
This from the guy who thinks Buchanan was the president just after Jefferson. The schedule of the conference has this for April 2: "7 p.m. — Dr. Ward Churchill, genocide scholar, 'Genocide and the Indigenous Peoples of the U.S.'"
Update: the Dakota Studies program at SMSU is apparently ending, too.


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This ministry is ideal for the youth of our parish who wish to participate in the celebration of the Mass in a special way. Boys and girls are welcome.
Contact Stuart Neck: [email protected]
Veronica Monarch: [email protected]
Inspired by the Blessed Mother, we promote love and respect the House of the Lord. We care for the altar, sacristies, chapel and linens in the spirit of fellowship.
Contact Kathy Dumoit: [email protected]
Members create an environment in our church with symbols and visuals to set a reflective mood for worship.
Contact the Parish Office
Extraordinary Ministers of Holy Communion (EMHC)
EMHC are called to serve God's people in a very special way. In ministering to the assembly at Mass, we help awaken in each communicant the fullest meaning of the Eucharist.
Contact Jamie Burns: [email protected]
This is a great ministry that includes the whole family. Each Mass we need at least three people from a family to bring our community gifts to the priest at the altar.
Greeters/Ushers
Men and women 15 years of age and older personally welcome all our worshipers, help them with seating, and take up the collection.
Contact Pastoral Office
Lectors proclaim the Word of God each week in our liturgy. Our mission is to make the Word of God come alive in the hearts and minds of our worshipers.
This ministry is offered every 2nd and 4th Sunday of each month during the 9:30 am Sunday Mass. This ministry is for children in grades PK-1. Adult and teen ministry leaders proclaim and break open the scriptures for the children following the lesson provided by Pflaum. Parents of the children who often participate in the Children's Liturgy of the Word are encouraged to join the CLOW Parent Email List on Flocknote. If interested please text "Add me to CLOW" to 84576 and you will automatically be added to the email list. Emails will be sent the 1st and 3rd Thursday of each month in preparation for CLOW the following Sunday.
For questions or to join the ministry please contact:
Contact Annette O'Driscoll: [email protected]


text:
Involvement of DMT1 in uptake of Cd in MDCK cells: Role of protein kinase C
Luisa Olivi, Jeanne Sisk, Joseph Bressler
The involvement of iron (Fe) transporters in the uptake of cadmium (Cd) was examined in Madin-Darby kidney cells (MDCK). The uptake of Cd displayed properties that are associated with the Fe transporter divalent metal transporter 1 (DMT1): For example, the uptake of Cd and Fe was reduced by altering the cell membrane potential. The uptake of Cd was blocked by Fe, and the uptake of Fe was blocked by Cd. Also, the uptake of Cd and Fe was higher in MDCK cells bathed in a buffer at low pH. Increased uptake of Fe and Cd was observed in the HEK-293 cell line overexpressing DMT1. Overnight treatment of MDCK cells with the protein kinase C activator phorbol 12,13-dibutyrate (PDBu) resulted in increased uptake of Cd and Fe and an increase in DMT1 mRNA. An increase in newly transcribed DMT1 mRNA was not observed, suggesting that PDBu does not increase DMT1 mRNA by activating transcription. Rather, the increase was most likely due to greater stability of DMT1 mRNA, because the rate of degradation of DMT1 mRNA was slower in MDCK cells treated with PDBu. Our results suggest that Fe and Cd are transported in MDCK cells by a transporter with biochemical properties similar to those of DMT1.
American Journal of Physiology - Cell Physiology
https://doi.org/10.1152/ajpcell.2001.281.3.c793
Divalent metal transporter 1
Madin-Darby canine kidney cells
10.1152/ajpcell.2001.281.3.c793
Dive into the research topics of 'Involvement of DMT1 in uptake of Cd in MDCK cells: Role of protein kinase C'. Together they form a unique fingerprint.
solute carrier family 11- (proton-coupled divalent metal ion transporters), member 2 Medicine & Life Sciences 100%
Madin Darby Canine Kidney Cells Medicine & Life Sciences 76%
Cadmium Medicine & Life Sciences 70%
Protein Kinase C Medicine & Life Sciences 58%
Phorbol 12,13-Dibutyrate Medicine & Life Sciences 29%
Messenger RNA Medicine & Life Sciences 19%
HEK293 Cells Medicine & Life Sciences 7%
Membrane Potentials Medicine & Life Sciences 6%
Olivi, L., Sisk, J., & Bressler, J. (2001). Involvement of DMT1 in uptake of Cd in MDCK cells: Role of protein kinase C. American Journal of Physiology - Cell Physiology, 281(3 50-3), C793-C800. https://doi.org/10.1152/ajpcell.2001.281.3.c793
Involvement of DMT1 in uptake of Cd in MDCK cells : Role of protein kinase C. / Olivi, Luisa; Sisk, Jeanne; Bressler, Joseph.
In: American Journal of Physiology - Cell Physiology, Vol. 281, No. 3 50-3, 2001, p. C793-C800.
Olivi, L, Sisk, J & Bressler, J 2001, 'Involvement of DMT1 in uptake of Cd in MDCK cells: Role of protein kinase C', American Journal of Physiology - Cell Physiology, vol. 281, no. 3 50-3, pp. C793-C800. https://doi.org/10.1152/ajpcell.2001.281.3.c793
Olivi L, Sisk J, Bressler J. Involvement of DMT1 in uptake of Cd in MDCK cells: Role of protein kinase C. American Journal of Physiology - Cell Physiology. 2001;281(3 50-3):C793-C800. https://doi.org/10.1152/ajpcell.2001.281.3.c793
Olivi, Luisa ; Sisk, Jeanne ; Bressler, Joseph. / Involvement of DMT1 in uptake of Cd in MDCK cells : Role of protein kinase C. In: American Journal of Physiology - Cell Physiology. 2001 ; Vol. 281, No. 3 50-3. pp. C793-C800.
@article{724f6d9d24bf461095be5be9205336a7,
title = "Involvement of DMT1 in uptake of Cd in MDCK cells: Role of protein kinase C",
abstract = "The involvement of iron (Fe) transporters in the uptake of cadmium (Cd) was examined in Madin-Darby kidney cells (MDCK). The uptake of Cd displayed properties that are associated with the Fe transporter divalent metal transporter 1 (DMT1): For example, the uptake of Cd and Fe was reduced by altering the cell membrane potential. The uptake of Cd was blocked by Fe, and the uptake of Fe was blocked by Cd. Also, the uptake of Cd and Fe was higher in MDCK cells bathed in a buffer at low pH. Increased uptake of Fe and Cd was observed in the HEK-293 cell line overexpressing DMT1. Overnight treatment of MDCK cells with the protein kinase C activator phorbol 12,13-dibutyrate (PDBu) resulted in increased uptake of Cd and Fe and an increase in DMT1 mRNA. An increase in newly transcribed DMT1 mRNA was not observed, suggesting that PDBu does not increase DMT1 mRNA by activating transcription. Rather, the increase was most likely due to greater stability of DMT1 mRNA, because the rate of degradation of DMT1 mRNA was slower in MDCK cells treated with PDBu. Our results suggest that Fe and Cd are transported in MDCK cells by a transporter with biochemical properties similar to those of DMT1.",
keywords = "Cadmium, Divalent metal transporter 1, Madin-Darby canine kidney cells",
author = "Luisa Olivi and Jeanne Sisk and Joseph Bressler",
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T1 - Involvement of DMT1 in uptake of Cd in MDCK cells
T2 - Role of protein kinase C
AU - Olivi, Luisa
AU - Sisk, Jeanne
AU - Bressler, Joseph
N2 - The involvement of iron (Fe) transporters in the uptake of cadmium (Cd) was examined in Madin-Darby kidney cells (MDCK). The uptake of Cd displayed properties that are associated with the Fe transporter divalent metal transporter 1 (DMT1): For example, the uptake of Cd and Fe was reduced by altering the cell membrane potential. The uptake of Cd was blocked by Fe, and the uptake of Fe was blocked by Cd. Also, the uptake of Cd and Fe was higher in MDCK cells bathed in a buffer at low pH. Increased uptake of Fe and Cd was observed in the HEK-293 cell line overexpressing DMT1. Overnight treatment of MDCK cells with the protein kinase C activator phorbol 12,13-dibutyrate (PDBu) resulted in increased uptake of Cd and Fe and an increase in DMT1 mRNA. An increase in newly transcribed DMT1 mRNA was not observed, suggesting that PDBu does not increase DMT1 mRNA by activating transcription. Rather, the increase was most likely due to greater stability of DMT1 mRNA, because the rate of degradation of DMT1 mRNA was slower in MDCK cells treated with PDBu. Our results suggest that Fe and Cd are transported in MDCK cells by a transporter with biochemical properties similar to those of DMT1.
AB - The involvement of iron (Fe) transporters in the uptake of cadmium (Cd) was examined in Madin-Darby kidney cells (MDCK). The uptake of Cd displayed properties that are associated with the Fe transporter divalent metal transporter 1 (DMT1): For example, the uptake of Cd and Fe was reduced by altering the cell membrane potential. The uptake of Cd was blocked by Fe, and the uptake of Fe was blocked by Cd. Also, the uptake of Cd and Fe was higher in MDCK cells bathed in a buffer at low pH. Increased uptake of Fe and Cd was observed in the HEK-293 cell line overexpressing DMT1. Overnight treatment of MDCK cells with the protein kinase C activator phorbol 12,13-dibutyrate (PDBu) resulted in increased uptake of Cd and Fe and an increase in DMT1 mRNA. An increase in newly transcribed DMT1 mRNA was not observed, suggesting that PDBu does not increase DMT1 mRNA by activating transcription. Rather, the increase was most likely due to greater stability of DMT1 mRNA, because the rate of degradation of DMT1 mRNA was slower in MDCK cells treated with PDBu. Our results suggest that Fe and Cd are transported in MDCK cells by a transporter with biochemical properties similar to those of DMT1.
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SP - C793-C800


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Home / Media / Rich Paul on LeBron James' and Michael Jordan's paths to greatness: 'The road for LeBron was just as hard, if not harder'
Rich Paul on LeBron James' and Michael Jordan's paths to greatness: 'The road for LeBron was just as hard, if not harder'
By Jonathan Sherman
LeBron James was recently named the second-best player in the history of the NBA by The Athletic.
When The Athletic announced that it would be counting down the 75 greatest players in NBA history, there is little doubt that fans knew James would end up very close to the top spot.
However, those same fans also likely knew that Chicago Bulls legend Michael Jordan could be named to the No. 1 spot.
With James officially being placed at No. 2, it is now clear that Jordan will claim that top spot. In response to the honor, James' agent and longtime friend Rich Paul made it clear that James' road to NBA immortality has been just as difficult as Jordan's was.
"The road for LeBron was just as hard, if not harder than the road was for Michael," Paul told The Athletic. "For a number of reasons. And I think the biggest reason is, everyone wants you to do something the way somebody else did it previously.
"LeBron was a kid. (The media) wanted LeBron to be like Mike; they wanted Michael to speak to them in any capacity, which he probably didn't. They wanted Michael to be his friend, which he probably wasn't. They also wanted LeBron to act like, be like Michael, and he wasn't.
"There were more people that smiled and hoped LeBron failed than there ever was rooting for him to succeed in the beginning."
Of course, Paul's opinion on the matter isn't exactly objective. Paul and James have worked together for years and have built an empire together.
Paul has also become one of the most powerful agents in the entire sports world.
As for James, he is hoping to lead his Los Angeles Lakers out of a tough spot. Though James is averaging an impressive 29.1 points, 7.9 rebounds and 6.5 assists per game this season, the Lakers are sorely disappointing fans this season.
They currently sit in the No. 9 seed in the Western Conference with a record of 27-31.
The Lakers won their last game before the All-Star break against the Utah Jazz on Wednesday night. Although L.A. was able to snap a three-game losing streak, star big man Anthony Davis went down with a gruesome ankle injury.
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About Jonathan Sherman
Jonathan is a freelance writer, filmmaker, and passionate fan of the NBA. In the past Jonathan has covered politics, entertainment, travel, and more. He is a proud contributor of Lakers Daily.


text:
Country Slovenia
si Slovenia en
Find the spare parts >
Nutcracker Strongman
Nutcracker in 18/10 stainless steel. Limited edition of 999 numbered copies and 9 artist's proofs.
Length (cm): 15.20
Width (cm): 11.00
Design Marcel Wanders
Marcel Wanders grew up in Boxtel, the Netherlands, and graduated cum laude from the School of the Arts Arnhem in 1988. Marcel Wanders' fame started with his iconic Knotted Chair, which he produced......
COD MW36
A strapping heart-breaker. That is how Marcel Wanders pictures the character that inspired this original nutcracker. Ladies and gentlemen, welcome the world's strongest man! With his barbell loaded with big golden balls to show off his amazing strength, his face grimacing from the effort, his muscles rippling and his feet planted firmly on the platform. Marcel Wanders has fun with this character, concealing the functional elements of the nutcracker within the design. The platform conceals the hollow where the nut is placed, turning the weights lowers the cursor and the lace-up boots typically sported by weight lifters form the element that actually cracks the nut.


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One US Bank Plaza (formerly One Mercantile Center) is a 36-story building in Downtown St. Louis, Missouri. The  building is topped by an antenna that raises the total building to . In the 1990s the Ambassador Building next to it was razed and became part of the building's plaza.

The building has a Structural Expressionism style.  It was originally built for Mercantile Bancorporation which was bought out by Firstar in 1999 and then became U.S. Bancorp in 2001.

Major occupants
Thompson Coburn, LLP
US Bank

See also
List of tallest buildings in Missouri
List of tallest buildings in St. Louis

References

Office buildings completed in 1976
Skyscraper office buildings in St. Louis
U.S. Bank buildings
Downtown St. Louis
Buildings and structures in St. Louis
1976 establishments in Missouri

redpajama_set_name: RedPajamaWikipedia


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Cherry Dell is an extinct town in Marion County, in the U.S. state of Missouri.

A post office called Cherry Dell was established in 1879, and remained in operation until 1906. According to tradition, the community was named for a cherry tree near the original town site.

References

Ghost towns in Missouri
Former populated places in Marion County, Missouri