At the personal injury law practice of Goldberg Noone LLC, our attorneys pride themselves on being straight and also very closely involved with every one of our client's situations. We comprehend that in the event you're harmed in some sort of automobile crash, you're mosting likely to be encountering a lot of challenging inquiries. We feel you be entitled to the right to speak directly with among our attorneys, not a instance worker, legal assistant or staffer. Our auto accident lawyers have the solutions you're looking for, and it never ever sets you back a thing to speak to one directly.
When you keep the law firm of Goldberg Noone LLC, we function to obtain the most desirable economic settlement in our efforts to attempt to assist put your life, and the lives of your member of the family, back with each other once more. When you have actually been preyed on in a serious collision that was brought on by another person's carelessness or negligence, you're qualified under Florida legislation to be fairly as well as appropriately compensated for your damages.
We're all aware of the nonstop legal representative advertising on tv as well as radio that we hear everyday and also evening. Even if a law firm picks to spend their bucks on blasting out tv ads does not mean they will be the right suitable for you and also your accident injury circumstance. There are a variety of lawyers who are not also based in Lee Area, but have selected to market themselves below in order to capitalize on the a great deal of regional car, motorbike and also trucking crashes.
We feel you need to work with legal representatives that live here, and also who have exercised legislation below long enough to completely comprehend the regional judicial system as well as those that practice within it. Our company's managing companion, Scot D. Goldberg, was birthed and also raised in Ft Myers, and also his long-lasting lawful links and 20-plus years safeguarding individuals's rights supply him with many understandings into exactly how to efficiently clear up court trials in Lee Region, Charlotte Region as well as Hendry County. A giant, out-of-town law practice might have the money for signboards and also incessant TELEVISION and radio ads, but have actually never ever tried a situation in your area in their entire profession.
I didn't recognize the extent of pain I would be in till 2 weeks after the crash-- can I still get a person to pay for my therapy?
What does PIP insurance coverage mean, and also how does it affect my injuries?
The individual that collapsed right into me is currently refuting he was at fault-- what do I do?
The various other man's insurance company keeps calling, asking me to sign a release kind-- should I do it?
Many individuals who are seriously hurt in an auto mishap, or experience the disastrous event of shedding a loved one, have no suggestion about what will certainly take place following. There are so many legal issues that turn up, many concerns to be answered, and frankly people are unprepared for just how suffering a severe injury will impact their lives, as well as the lives of their households.
At Goldberg Noone, our Fort Myers personal injury attorneys have spent their entire professions assisting people that are victims of a car collision that was not their mistake. We also have an complex understanding of the insurance policy market, with attorneys that have actually invested years as elderly insurance claims analysts at a few of the nation's largest vehicle insurer. Unless you have had the unfortunate scenario to have suffered through the trauma as well as the dramatization of managing a huge insurer after a crash, you have no idea what a problem it can become.
WHY SHOULD I EMPLOY THE GOLDBERG NOONE LAW COMPANY TO TAKE CARE OF MY CAR MISHAP INSTANCE?
We have the answers to all your legal inquiries. Managing hostile insurance coverage asserts insurance adjusters as well as being bullied by frightening insurance lawyers can be a nightmare, as well as you must preserve the services of a law office with the full capacity to level the playing field to make certain all of your legal rights are completely secured.
The amount of accident instances have we managed?
What portion of my time do I spend in my practice representing individuals that have been injured in an accident?
Would certainly you be representing me directly or would an additional lawyer in your firm?
Do you have professionals in the medical and also insurance policy fields to assist me show my instance?
How long do I have before I determine to employ you and take legal action against the individual or business that caused my injury?
Due to our long history of dealing with all kinds of automobile crash situations, we have the responses you need to aid place your life back together.
If you ride a bike, you've with any luck provided a lot of major consideration to the fundamental threats associated with being a cyclist. Smart cyclists, both newbies as well as long-time, experienced cyclists, do everything within their power to ensure they are as secure as they can perhaps be when out when driving of Southwest Florida. The appropriate protective garments, keeping their bike maintained effectively to ride securely, ongoing risk-free biker training and education and learning-- all of these points work together to maintain you from being seriously hurt. As well as naturally, there are many viewpoints available on whether bikers should put on a safety helmet, or otherwise.
Headgear laws in Florida are a hot subject for bicycle riders. Among the reasons you ride to start with is your love for the flexibility of being behind the handlebars on the open roadway. That exact same liberty implies, in Florida at least and also presuming some other fundamental factors like age, you have the selection of whether you are mandated to put on one, or go without. As accident attorneys that have managed motorbike accident targets daily for the past 20 years, the lawyers at Goldberg Noone, LLC, recognize that numerous bicycle riders have made the personal decision to do without a safety helmet, which remains in conformity with the legislations of Florida. In Florida, the stats show that helmet selection is almost precisely at 50/50 pertaining to bikers who use one and also those that don't. Also, there are research studies that reveal safety helmets are not a 100% foolproof way to avoid severe head injuries, or perhaps a bike collision death.
Nevertheless, our law practice takes the position that putting on a helmet is a good suggestion.
If you or a individual you appreciate has been the victim of a bad bike accident, your really initial priority needs to be to obtain the prompt medical care you need. NOTHING is much more vital than doing everything you can to start the procedure of recuperating and also healing from your injuries. In the majority of the motorbike collision cases we have actually been involved in, the hurt victim does not immediately think about that is going to pay their clinical bills, or compensate them for being not able to work and also support themselves and also their households.
Given That Goldberg Noone, LLC, ( previously known as Goldberg, Racila, D'Alessandro & Noone), opened our doors in 2000, we've helped hundreds of bike accident victims in their efforts to make their lives entire once again. We withstand the insurance companies that will be most likely attempting to get you to accept some fast, low-ball settlement check, simply to obtain you to go away. When you keep our company, your troubles promptly become our problems. We want you to focus on recovering, as well as recovering from the destruction as well as injury complying with a motorcycle crash. We're below to go to battle for you, and also to take care of every one of the lawful hassles associated with seeing to it that you are relatively as well as rapidly compensated for your losses.
We have actually represented some motorcyclists greater than as soon as, also. Unfortunately, long-time motorcyclists who have actually been on the roadway for a life time are commonly involved in multiple accidents throughout the years, and also they have actually concerned depend on our committed experience in protecting their civil liberties in getting economic compensation. Being in a significant motorcycle mishap suggests you will be facing a big number of essential questions, and also forced into making very vital decisions regarding your life and future, and also we're right here to help you survive that process. We boast of the work we provide for accident targets, and also you can review what several of our past customers have said concerning us here.
There are lots of factors that can cause a motorbike collision, as well as some all-natural circumstances that make some parts of Florida a lot more dangerous for cyclists than others. 94% of individuals hurt in bike accidents are Florida locals. With our abundance of excellent view website weather as well as plenty of motorcycle-friendly roads in the Sunlight State, it's no surprise that bike fanatics are cruising Florida in large numbers.
A motorcycle collision can occur under a variety of scenarios. A distracted driver, a drunk chauffeur or a motorist that just does not see the motorcycle commonly strikes a cyclist. The most common, non-fatal injury received in a bike collision is a fracture, adhered to by internal organ injuries. Although there are many variables that may determine how severe an injury one may endure, motorcycle accidents can cause a arm or leg amputation, serious "road rash" injuries, life-long disfigurement, traumatic brain damage and several other horrific results. Additionally, you may be incapable to return to function and also gain a living to sustain your household, and also the related clinical costs and consistent rehab can mess up a family members. When your life has been shaken up after a bike crash, the hiring of the right motorbike accident lawyer can be crucial.
Investigatory study and tireless exploration will certainly be your finest defense ought to you go to trial as a result of your injuries, and our comprehensive understanding of every facet of Florida motor vehicle mishap law is the core of our support in defending your civil liberties under the regulation.
As you can envision, virtually every element of a accident including a huge industrial car-- like a dump truck, 18-wheeler or semi tractor-trailer-- is vastly different than what takes place in a guest lorry crash. In the Fort Myers location, many devastating accidents involving dump vehicles and also tractor-trailers, as well as happen along stretches of roads often utilized by business carriers that are carrying products from other cities in Florida. As an example, State Road 82 in eastern Lee County is infamous for the worrying variety of poor collisions that occur there. The road is a slim, dark and extremely traveled connection to the eastern shore as well as various other inland cities, and also the vehicles will certainly commonly travel over night or in the extremely early morning hrs. When you incorporate that with morning travelers avoiding to function or institution, specifically prior to sunrise, it can be a extremely lethal mix.
Most of tool and also large-sized trucking, logistics and also transport firms have treatments they will certainly pass in the event of a serious collision. As part of their "loss prevention" efforts, they will quickly send off a team to a accident scene in order to take photos, dimensions, as well as witness declarations, if offered, in order to record any type of proof. Certainly, they are trying to restrict any kind of responsibility they might have when it pertains to showing fault, and also limit the efforts of the hurt accident victim to rightfully accumulate any kind of financial damages as a result of the accident.
The other thing that trucking companies have are legal representatives-- great deals of them. When their attorneys are informing their insurers to offer you a fast, low-ball deal, you can bet you'll need an knowledgeable trucking crash attorney in your corner.
Trucking mishaps consist of a very specialized area of motor vehicle mishap cases.
This is because large business trucks and also the businesses that utilize them undergo many guidelines and also regulations that do not apply to exclusive lorries. As a result, if a individual is hurt or killed as a over at this website result of a collision with a industrial lorry (such as a semi tractor trailer rig), it is very essential to hire trucking mishap attorneys who recognize with the demands which should be met by trucking firms. Crucial proof can be forever lost if certain actions are not required to guarantee its preservation. Furthermore, there are resources of important details which a trucking accident attorney who is knowledgeable in this area will have the ability to acquire. This information may be neglected by an attorney that is not well versed in the laws which relate to the industrial trucking market. The attorneys of Goldberg Noone, LLC, have actually committed to remaining abreast of the complicated as well as ever-changing state as well as federal regulations which apply to commercial vehicles. The Goldberg Company has actually effectively stood for various customers in injury and also wrongful death cases which were the result of trucking accidents.
Trucking accidents comprise a really customized area of automobile mishap cases.
This is because huge commercial trucks and the businesses that utilize them go through numerous guidelines as well as laws that do not relate to private vehicles. Therefore, if a individual is hurt or killed because of a crash with a commercial car (such as a semi tractor trailer rig), it is really vital to employ trucking crash lawyers who know with the requirements which must be fulfilled by trucking business. Essential evidence can be for life shed if particular steps are not required to guarantee its conservation. Additionally, there are sources of crucial info which a trucking accident attorney that is experienced in this field will be able to obtain. This information may be ignored by an lawyer who is not well versed in the legislations which relate to the industrial trucking industry. The lawyers of Goldberg Noone, LLC, have dedicated to remaining abreast of the complex as well as ever-changing state as well as federal policies which relate to commercial automobiles. The Goldberg Company has efficiently represented many customers in personal injury and also wrongful death situations which were the result of trucking crashes.


Here are some healthy alternatives and swaps you can make for an easy, at-home ice cream bar.
We have to start with the base of the ice cream sundae – by talking about the ice cream! Bye-bye super high fat, calorie-filled, zero nutritional value ice cream. I recently tried Swell, The Next Wave of Ice Cream (in a variety of flavors!) and it is so so good. It's not "nice" cream, it's actual creamy ice cream that can actually fuel your body. No matter which flavor you choose from (my favorite happens to be the Dark Chocolate Toffee – because, chocolate), each flavor will always have the 10g of protein per serving. Not to mention, the ingredients are clean. No artificial colors, binders, gums or preservatives, which is super hard to find in ice cream!
Instead of the standard sugar-coated fruit, or fruit that has been soaking in syrups and preservatives that you may normally see when building an ice cream sundae, try adding in fresh fruit instead. Right now it is perfect berry season (strawberries, especially!), so stop by your local farmer's market or grocery store to buy some organic berries to add the perfect hint of sweetness to your ice cream.
The average person has about 10g of fiber in their diet when the suggested amount is 25g. Adding in chia seeds and hemp seeds is such an easy way to bring in additional fiber into your diet. It also adds a little bit of nuttiness and texture to each bite that you will totally love. If you love nutty flavors, you can also try making your own trail mix with your favorite nuts and seeds. I always have a batch of my own pistachio, cashew, walnut mixture in my freezer (pro tip: keeping your nuts in the freezer will make them extra crunchy!).
Cacao nibs are basically cocoa beans that have been roasted and broken into nibs or small pieces. It adds a little bit of that chocolate/cocoa flavor without the added sugar and fats. Another alternative to standard chocolate chips is to opt for vegan chocolate chips which are just as delicious!
Depending on what type of granola you get, you can get some that have ingredients like quinoa and millet. Both of these are high in Vitamin B and Magnesium.Magnesium is awesome for bone health! Before purchasing any granola from the store, look at the ingredients to make sure that no additional sweeteners have been added.
If you have any questions on where to find Swell Foods ice cream you can click here to view their store locator or you can purchase this online!
This post was sponsored by Swell Foods but all thoughts and opinions are 100% my own.
Looks like a great option to cool off this summer! I'm a big fan of frozen treats!
It's getting so hot lately, so yes I hope you try it out!
YUM! This looks delicious. Can I come over for some ice cream?!
Wow, you create the prettiest ice cream sundaes! I love the name of that brand – it's so comforting.


1998. Stattersfield, A.J., M.J. Crosby, A.J. Long, and D.C. Wege. 1998. Endemic Bird Areas of the World: Priorities for Biodiversity Conservation. Cambridge, United Kingdom: BirdLife International., Stattersfield, A. J., Crosby, M. J., Long, Adrian J., and Wege, David C. This polygon shapefile depicts Endemic Bird Areas (EBAs) in Kenya. EBAs are sites where two or more bird species of "restricted range" (less than 5... BirdLife International.
1998. Istituto di ecologia applicata (Rome, Italy). This polygon shapefile represents the predicted mammal diversity, or the total number of mammal species, in Kenya.The greatest concentration of mam... World Resources Institute.
1998. UNEP executive series. This dataset portrays locations of sable antelope sites on the eastern coast of Kenya. Included are locations such as the Shimba Hills Reserve (abo... UNEP executive series.


My research interests revolve around non-coding variation, evolution of cancer genomes, and genomic response to immunotherapies.
Weinhold, Nils, et al. "Genome-wide analysis of noncoding regulatory mutations in cancer." Nature genetics 46.11 (2014): 1160-1165.
Shinbrot, Eve, et al. "Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication." Genome research 24.11 (2014): 1740-1750.
Cancer Genome Atlas Research Network. "Integrated genomic characterization of endometrial carcinoma." Nature 497.7447 (2013): 67-73.


text:
Imports System.Data
Imports System.Data.Common
Imports bv.common.Enums

Public Class NotificationSubscription_DB
    Inherits BaseDbService

    Public Const TableEventSubscription As String = "EventSubScription"
    Public Overrides Function GetDetail(ByVal ID As Object) As System.Data.DataSet
        Dim ds As New DataSet
        Try
            Dim cmd As IDbCommand = CreateSPCommand("spNotificationSubscription_SelectDetail")
            AddParam(cmd, "@ClientID", EIDSS.model.Core.EidssUserContext.ClientID)
            AddParam(cmd, "@LangID", bv.model.Model.Core.ModelUserContext.CurrentLanguage)
            Dim da As DbDataAdapter = CreateAdapter(cmd)
            da.Fill(ds, TableEventSubscription)
            ds.Tables(TableEventSubscription).Columns("Subscription").ReadOnly = False
            ds.AcceptChanges()
            Return ds
        Catch ex As Exception
            m_error = New ErrorMessage(StandardError.FillDatasetError, ex)
            Return Nothing
        End Try

    End Function

    Public Overrides Function PostDetail(ByVal ds As System.Data.DataSet, ByVal postType As Integer, Optional ByVal transaction As System.Data.IDbTransaction = Nothing) As Boolean
        If ds Is Nothing Then Return True
        Try
            For Each row As DataRow In ds.Tables(TableEventSubscription).Rows
                If row.RowState = DataRowState.Modified AndAlso row.HasVersion(DataRowVersion.Original) AndAlso row("Subscription").Equals(row("Subscription", DataRowVersion.Original)) Then
                    row.AcceptChanges()
                End If
            Next
            BaseDbService.ExecPostProcedure("spNotificationSubscription_Post", ds.Tables(TableEventSubscription), Connection, transaction)
        Catch ex As Exception
            m_Error = New ErrorMessage(StandardError.PostError, ex)
            Return False
        End Try
        Return True

    End Function
End Class

redpajama_set_name: RedPajamaGithub


Bevill and Associates LLC provides comprehensive psychosexual evaluation and assessment for sexual offenses, professional sexual misconduct, as well as a return to practice and fitness for duty recommendations for professionals who are faced with allegations regarding boundary violations.
All evaluations and assessments* are administered by Al Bevill, M.S, LPC, NCC, CCFC. Al is a Licensed Professional Counselor and a Certified Clinical Forensic Counselor certified through the National Association of Forensic Counselors.
* Polygraph administered by License – Certified Polygraph Examiner.


text:
Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses
Guo Rung You, Ann Joy Cheng, Li Yu Lee, Yu Chen Huang, Hsuan Liu, Yin Ju Chen, Joseph T. Chang
Graduate Institute of Biomedical Materials and Tissue Engineering
School of Biomedical Engineering
Taipei Medical University Hospital
TMU Research Center of Biomedical Devices
International Ph.D. Program in Biomedical Engineering
Background: Radiotherapy is an indispensable treatment modality in head and neck cancer (HNC), while radioresistance is the major cause of treatment failure. The aim of this study is to identify a prognostic molecular signature associated with radio-resistance in HNC for further clinical applications. Methods: Affymetrix cDNA microarrays were used to globally survey different transcriptomes between HNC cell lines and isogenic radioresistant sublines. The KEGG and Partek bioinformatic analytical methods were used to assess functional pathways associated with radioresistance. The SurvExpress web tool was applied to study the clinical association between gene expression profiles and patient survival using The Cancer Genome Atlas (TCGA)-head and neck squamous cell carcinoma (HNSCC) dataset (n = 283). The Kaplan-Meier survival analyses were further validated after retrieving clinical data from the TCGA-HNSCC dataset (n = 502) via the Genomic Data Commons (GDC)-Data-Portal of National Cancer Institute. A panel maker molecule was generated to assess the efficacy of prognostic prediction for radiotherapy in HNC patients. Results: In total, the expression of 255 molecules was found to be significantly altered in the radioresistant cell sublines, with 155 molecules up-regulated 100 down-regulated. Four core functional pathways were identified to enrich the up-regulated genes and were significantly associated with a worse prognosis in HNC patients, as the modulation of cellular focal adhesion, the PI3K-Akt signaling pathway, the HIF-1 signaling pathway, and the regulation of stem cell pluripotency. Total of 16 up-regulated genes in the 4 core pathways were defined, and 11 over-expressed molecules showed correlated with poor survival (TCGA-HNSCC dataset, n = 283). Among these, 4 molecules were independently validated as key molecules associated with poor survival in HNC patients receiving radiotherapy (TCGA-HNSCC dataset, n = 502), as IGF1R (p = 0.0454, HR = 1.43), LAMC2 (p = 0.0235, HR = 1.50), ITGB1 (p = 0.0336, HR = 1.46), and IL-6 (p = 0.0033, HR = 1.68). Furthermore, the combined use of these 4 markers product an excellent result to predict worse radiotherapeutic outcome in HNC (p < 0.0001, HR = 2.44). Conclusions: Four core functional pathways and 4 key molecular markers significantly contributed to radioresistance in HNC. These molecular signatures may be used as a predictive biomarker panel, which can be further applied in personalized radiotherapy or as radio-sensitizing targets to treat refractory HNC.
BMC Cancer
IGF1R
IL-6
ITGB1
LAMC2
Radioresistance
Dive into the research topics of 'Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses'. Together they form a unique fingerprint.
Head and Neck Neoplasms Medicine & Life Sciences 100%
Computational Biology Medicine & Life Sciences 93%
Squamous Cell Carcinoma of Head and Neck Medicine & Life Sciences 49%
Atlases Medicine & Life Sciences 47%
Radiotherapy Medicine & Life Sciences 30%
Radio Medicine & Life Sciences 22%
Additional file 1: of Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses
Chen, Y. (Contributor), Chang, J. T. (Creator), Cheng, A. (Contributor), Huang, Y. (Creator), Lee, L. (Creator), You, G. (Contributor) & Liu, H. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.7587455.v1, https://doi.org/10.6084%2Fm9.figshare.7587455.v1
You, G. (Contributor), Cheng, A. (Contributor), Lee, L. (Creator), Huang, Y. (Creator), Liu, H. (Creator), Chen, Y. (Contributor) & Chang, J. T. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4366814.v1, https://doi.org/10.6084%2Fm9.figshare.c.4366814.v1
Liu, H. (Creator), Cheng, A. (Contributor), Chen, Y. (Contributor), You, G. (Contributor), Chang, J. T. (Creator), Huang, Y. (Creator) & Lee, L. (Creator), Figshare, 2019
You, G. R., Cheng, A. J., Lee, L. Y., Huang, Y. C., Liu, H., Chen, Y. J., & Chang, J. T. (2019). Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses. BMC Cancer, 19(1), 64. [64]. https://doi.org/10.1186/s12885-018-5243-3
Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses. / You, Guo Rung; Cheng, Ann Joy; Lee, Li Yu et al.
In: BMC Cancer, Vol. 19, No. 1, 64, 14.01.2019, p. 64.
You, GR, Cheng, AJ, Lee, LY, Huang, YC, Liu, H, Chen, YJ & Chang, JT 2019, 'Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses', BMC Cancer, vol. 19, no. 1, 64, pp. 64. https://doi.org/10.1186/s12885-018-5243-3
You GR, Cheng AJ, Lee LY, Huang YC, Liu H, Chen YJ et al. Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses. BMC Cancer. 2019 Jan 14;19(1):64. 64. doi: 10.1186/s12885-018-5243-3
You, Guo Rung ; Cheng, Ann Joy ; Lee, Li Yu et al. / Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses. In: BMC Cancer. 2019 ; Vol. 19, No. 1. pp. 64.
@article{c33a29d8532e42b7b291baa633232cd1,
title = "Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses",
abstract = "Background: Radiotherapy is an indispensable treatment modality in head and neck cancer (HNC), while radioresistance is the major cause of treatment failure. The aim of this study is to identify a prognostic molecular signature associated with radio-resistance in HNC for further clinical applications. Methods: Affymetrix cDNA microarrays were used to globally survey different transcriptomes between HNC cell lines and isogenic radioresistant sublines. The KEGG and Partek bioinformatic analytical methods were used to assess functional pathways associated with radioresistance. The SurvExpress web tool was applied to study the clinical association between gene expression profiles and patient survival using The Cancer Genome Atlas (TCGA)-head and neck squamous cell carcinoma (HNSCC) dataset (n = 283). The Kaplan-Meier survival analyses were further validated after retrieving clinical data from the TCGA-HNSCC dataset (n = 502) via the Genomic Data Commons (GDC)-Data-Portal of National Cancer Institute. A panel maker molecule was generated to assess the efficacy of prognostic prediction for radiotherapy in HNC patients. Results: In total, the expression of 255 molecules was found to be significantly altered in the radioresistant cell sublines, with 155 molecules up-regulated 100 down-regulated. Four core functional pathways were identified to enrich the up-regulated genes and were significantly associated with a worse prognosis in HNC patients, as the modulation of cellular focal adhesion, the PI3K-Akt signaling pathway, the HIF-1 signaling pathway, and the regulation of stem cell pluripotency. Total of 16 up-regulated genes in the 4 core pathways were defined, and 11 over-expressed molecules showed correlated with poor survival (TCGA-HNSCC dataset, n = 283). Among these, 4 molecules were independently validated as key molecules associated with poor survival in HNC patients receiving radiotherapy (TCGA-HNSCC dataset, n = 502), as IGF1R (p = 0.0454, HR = 1.43), LAMC2 (p = 0.0235, HR = 1.50), ITGB1 (p = 0.0336, HR = 1.46), and IL-6 (p = 0.0033, HR = 1.68). Furthermore, the combined use of these 4 markers product an excellent result to predict worse radiotherapeutic outcome in HNC (p < 0.0001, HR = 2.44). Conclusions: Four core functional pathways and 4 key molecular markers significantly contributed to radioresistance in HNC. These molecular signatures may be used as a predictive biomarker panel, which can be further applied in personalized radiotherapy or as radio-sensitizing targets to treat refractory HNC.",
keywords = "Head and neck cancer, IGF1R, IL-6, ITGB1, LAMC2, Prognosis, Radioresistance, Head and neck cancer, IGF1R, IL-6, ITGB1, LAMC2, Prognosis, Radioresistance",
author = "You, {Guo Rung} and Cheng, {Ann Joy} and Lee, {Li Yu} and Huang, {Yu Chen} and Hsuan Liu and Chen, {Yin Ju} and Chang, {Joseph T.}",
note = "Funding Information: This project was supported by the grants from Chang Gung Memorial Hospital (CORPG3E0111, CORPG3G0931, CORPG3G0941, CPRPG3E0021~2). The role of the funding body JTC for these grants include the design of the study, collection, analysis and interpretation of data, and writing the manuscript. Publisher Copyright: {\textcopyright} 2019 The Author(s).",
journal = "BMC Cancer",
T1 - Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses
AU - You, Guo Rung
AU - Cheng, Ann Joy
AU - Lee, Li Yu
AU - Huang, Yu Chen
AU - Liu, Hsuan
AU - Chen, Yin Ju
AU - Chang, Joseph T.
N1 - Funding Information: This project was supported by the grants from Chang Gung Memorial Hospital (CORPG3E0111, CORPG3G0931, CORPG3G0941, CPRPG3E0021~2). The role of the funding body JTC for these grants include the design of the study, collection, analysis and interpretation of data, and writing the manuscript. Publisher Copyright: © 2019 The Author(s).
N2 - Background: Radiotherapy is an indispensable treatment modality in head and neck cancer (HNC), while radioresistance is the major cause of treatment failure. The aim of this study is to identify a prognostic molecular signature associated with radio-resistance in HNC for further clinical applications. Methods: Affymetrix cDNA microarrays were used to globally survey different transcriptomes between HNC cell lines and isogenic radioresistant sublines. The KEGG and Partek bioinformatic analytical methods were used to assess functional pathways associated with radioresistance. The SurvExpress web tool was applied to study the clinical association between gene expression profiles and patient survival using The Cancer Genome Atlas (TCGA)-head and neck squamous cell carcinoma (HNSCC) dataset (n = 283). The Kaplan-Meier survival analyses were further validated after retrieving clinical data from the TCGA-HNSCC dataset (n = 502) via the Genomic Data Commons (GDC)-Data-Portal of National Cancer Institute. A panel maker molecule was generated to assess the efficacy of prognostic prediction for radiotherapy in HNC patients. Results: In total, the expression of 255 molecules was found to be significantly altered in the radioresistant cell sublines, with 155 molecules up-regulated 100 down-regulated. Four core functional pathways were identified to enrich the up-regulated genes and were significantly associated with a worse prognosis in HNC patients, as the modulation of cellular focal adhesion, the PI3K-Akt signaling pathway, the HIF-1 signaling pathway, and the regulation of stem cell pluripotency. Total of 16 up-regulated genes in the 4 core pathways were defined, and 11 over-expressed molecules showed correlated with poor survival (TCGA-HNSCC dataset, n = 283). Among these, 4 molecules were independently validated as key molecules associated with poor survival in HNC patients receiving radiotherapy (TCGA-HNSCC dataset, n = 502), as IGF1R (p = 0.0454, HR = 1.43), LAMC2 (p = 0.0235, HR = 1.50), ITGB1 (p = 0.0336, HR = 1.46), and IL-6 (p = 0.0033, HR = 1.68). Furthermore, the combined use of these 4 markers product an excellent result to predict worse radiotherapeutic outcome in HNC (p < 0.0001, HR = 2.44). Conclusions: Four core functional pathways and 4 key molecular markers significantly contributed to radioresistance in HNC. These molecular signatures may be used as a predictive biomarker panel, which can be further applied in personalized radiotherapy or as radio-sensitizing targets to treat refractory HNC.
AB - Background: Radiotherapy is an indispensable treatment modality in head and neck cancer (HNC), while radioresistance is the major cause of treatment failure. The aim of this study is to identify a prognostic molecular signature associated with radio-resistance in HNC for further clinical applications. Methods: Affymetrix cDNA microarrays were used to globally survey different transcriptomes between HNC cell lines and isogenic radioresistant sublines. The KEGG and Partek bioinformatic analytical methods were used to assess functional pathways associated with radioresistance. The SurvExpress web tool was applied to study the clinical association between gene expression profiles and patient survival using The Cancer Genome Atlas (TCGA)-head and neck squamous cell carcinoma (HNSCC) dataset (n = 283). The Kaplan-Meier survival analyses were further validated after retrieving clinical data from the TCGA-HNSCC dataset (n = 502) via the Genomic Data Commons (GDC)-Data-Portal of National Cancer Institute. A panel maker molecule was generated to assess the efficacy of prognostic prediction for radiotherapy in HNC patients. Results: In total, the expression of 255 molecules was found to be significantly altered in the radioresistant cell sublines, with 155 molecules up-regulated 100 down-regulated. Four core functional pathways were identified to enrich the up-regulated genes and were significantly associated with a worse prognosis in HNC patients, as the modulation of cellular focal adhesion, the PI3K-Akt signaling pathway, the HIF-1 signaling pathway, and the regulation of stem cell pluripotency. Total of 16 up-regulated genes in the 4 core pathways were defined, and 11 over-expressed molecules showed correlated with poor survival (TCGA-HNSCC dataset, n = 283). Among these, 4 molecules were independently validated as key molecules associated with poor survival in HNC patients receiving radiotherapy (TCGA-HNSCC dataset, n = 502), as IGF1R (p = 0.0454, HR = 1.43), LAMC2 (p = 0.0235, HR = 1.50), ITGB1 (p = 0.0336, HR = 1.46), and IL-6 (p = 0.0033, HR = 1.68). Furthermore, the combined use of these 4 markers product an excellent result to predict worse radiotherapeutic outcome in HNC (p < 0.0001, HR = 2.44). Conclusions: Four core functional pathways and 4 key molecular markers significantly contributed to radioresistance in HNC. These molecular signatures may be used as a predictive biomarker panel, which can be further applied in personalized radiotherapy or as radio-sensitizing targets to treat refractory HNC.
KW - Head and neck cancer
KW - IGF1R
KW - IL-6
KW - ITGB1
KW - LAMC2
KW - Radioresistance
JO - BMC Cancer
JF - BMC Cancer

redpajama_set_name: RedPajamaCommonCrawl


text:
Fly Play.hf (estilizado como PLAY ) es una aerolínea islandesa de bajo costo con sede en la capital del país, Reykjavík. Opera una flota de aviones de la familia Airbus A320NEO con un centro de operaciones en el Aeropuerto Internacional de Keflavík.

La aerolínea es sucesora de la ya extinta WOW Air.

Historia
En julio de 2019, dos ex ejecutivos de WOW air, Arnar Már Magnússon y Sveinn Ingi Steinþórsson, anunciaron la formación de una nueva aerolínea, tentativamente llamada WAB air ("We Are Back").  Avianta Capital, un fondo de inversión irlandés propiedad de Aislinn Whittley-Ryan (hija de Michael Kell Ryan, uno de los fundadores de Ryanair) tenía una participación del 75%;  el resto estaba en manos de Neo, una empresa fundada por Magnússon y Steinþórsson.  La compañía tenía como objetivo operar seis aviones a 14 destinos en Europa y Estados Unidos, con un objetivo de un millón de pasajeros en el primer año. La nueva empresa solicitó un certificado de operador aéreo (AOC) de la Autoridad de Transporte de Islandia.

En noviembre de 2019, WAB air pasó a llamarse Play y se inició la contratación de personal operativo.  La aerolínea anunció que arrendaría Airbus A321 configurados con 200 asientos para pasajeros y comenzaría vuelos con dos aviones a seis destinos europeos en el invierno de 2019-2020.  También se planeó que la librea de la aerolínea fuera roja. A finales de 2019, Play tenía previsto servir inicialmente a seis destinos en Europa, que consisten en Alicante, Tenerife, Londres, París, Copenhague y Berlín. Había planes para introducir vuelos a cuatro destinos de América del Norte en la primavera de 2020. Play originalmente planeó comenzar sus operaciones con dos aviones Airbus A321 configurados para 200 asientos de pasajeros y agregar cuatro aviones más para el verano de 2020. En noviembre de 2020, la compañía había recibido un permiso de aterrizaje para solo tres aeropuertos, que consisten en Aeropuerto Internacional Londres Stansted, Aeropuerto Internacional Londres Gatwick y Aeropuerto Internacional de Dublín.

En abril de 2021, se anunció que un grupo formado por algunas de las empresas de inversión más grandes de Islandia y dos fondos de pensiones estaba proporcionando a PLAY cinco mil millones de coronas islandesas (40 millones de dólares).  También se confirmó que Birgir Jónsson reemplazaría a Arnar Már Magnússon como director general. En mayo de 2021, la aerolínea anunció el registro de su AOC, así como la adquisición de su primer avión, un Airbus A321neo anteriormente operado por la extinta aerolínea mexicana Interjet. Poco después, la aerolínea comenzó a vender billetes para sus primeros vuelos, cuyas operaciones se iniciaron con su vuelo inaugural desde el Aeropuerto Internacional Keflavík al Aeropuerto Internacional Londres Stansted el 24 de junio de 2021.  El mismo día de su vuelo inaugural, Play anunció una oferta pública inicial (OPI), buscando recaudar al menos $ 32 a 35 millones, después de lo cual sus acciones se negociarían en Nasdaq First North Growth Market de Islandia.

Destinos
Play opera los siguientes destinos:

Flota
La flota de Play consiste de las siguientes aeronaves, con una edad media de 3 años (noviembre de 2022):

Referencias

Aerolíneas de Islandia
Aerolíneas fundadas en 2019

redpajama_set_name: RedPajamaWikipedia


text:
High school football rule changes announced for…
SportsHigh School Sports
High school football rule changes announced for 2022 season
Pleasant Valley's Matt Kinoshita breaks loose against Chico during the 50th Almond Bowl held on Friday, Oct. 22, 2021 at at Asgard Yard at Pleasant Valley High School. Kinoshita is returning for his senior season in 2022 for the Vikings. (Matt Bates/Enterprise-Record file)
By Justin Couchot | jcouchot@chicoer.com | Chico Enterprise-Record
CHICO — High school football is quickly approaching, with all levels of the Chico High football team hosting Corning High School in scrimmages Friday evening. The Pleasant Valley freshman team has its first regular season home game Thursday, and Friday the PV junior varsity and varsity teams play West Valley.
Ahead of the start of games, let's take a look at the 2022 National Federation of State High School Associations Football Rules Changes and points of emphasis referees are being asked to target. There are seven rules changes and three points of emphasis in 2022.
2022 points of Emphasis
To begin, there are three points of emphasis that the NFHS is asking referees to focus on.
Targeting/defenseless player
Legal uniforms and equipment
All three of these do not come as a surprise. The first, targeting to defenseless players, comes from a pure safety point of view. Referees must keep this as a point of emphasis to keep players on the field.
Sportsmanship is one that I believe should be permanently on this list, and with it being on there it is clear that league officials believe it is still a problem and needs to be emphasized in the 2022 season.
As for legal uniforms and equipment, this is the point of emphasis that Pleasant Valley head football coach Mark Cooley would like to see more of being addressed. Cooley specifically pointed to knee pads that don't cover the players' knees. He also said that the way they make uniforms as a whole now is a huge issue.
2022 NFHS Rules Changes
The first on the list of rule changes for the 2022 high school football season is that the, "Team Box May Be Extended By State Association Adoption." This means that the team box may now be extended beyond the 25-yard line. The team box is where the players stand on the sidelines, meaning as a runner is heading towards the touchdown his teammates can now follow him to the end zone.
The only issue on first observance is officials or media are often present near the end zone attempting to make what are often critical calls, so it will be interesting to see how lenient referees are with enforcement of this.
The second rule change is that the, "Ball May Be Changed Between Downs." The further explanation given is that any game official may order the football changed between downs. Simple on the surface, but if not put in writing can become a controversy.
The third rule is that the number "0" is now legal for players to wear on the field.
The fourth rule is that a chop bock has been redefined. The explanation given states that, "A chop block has been redefined as an illegal combination block where contact is made above and below the waist."
The fifth rule states that clarification has been given to the offended team's game clock options following a foul committed with less than two minutes remaining in either half. No further explanation was given at this time in the release about the options.
The sixth rule states that there as been a new exception to the play clock administration added following a foul committed only by the defensive team. Like rule five, no further explanation has been given at this time.
The seventh and final new rule in 2022 is one that Cooley said is a huge one and one that stood out to him most on first glance. The rule states that there has been a new exception added that allows the passer of the football to legally throw the football away to conserve yardage. On first glance it would appear that this would wipe away many intentional grounding calls by quarterbacks, but it will be interesting to see how referees implement this in the early weeks of the season.
Biggs High School kicks off first for varsity football in the North State, with a game at 7 p.m. Friday at Delta. A full slate of opening games will begin Aug. 26 for a multitude of teams
Chico High will begin its season at 7:15 p.m. at Sutter, Pleasant Valley will begin its season at 7:30 p.m. at Corning, Oroville opens at 7:30 p.m. at Lindhurst, Paradise opens at 7:30 p.m. at home against Williams, Orland plays at Pierce at 7 p.m., Willows plays at Durham at 7 p.m. and Biggs will host Live Oak in the Wolverines' second game of the season at 7:30 p.m.
Las Plumas has a week one bye and will begin its season Sept. 2 at home against Enterprise.
Justin Couchot | Sports reporter
Justin Couchot covers sports for the Enterprise-Record. He previously covered sports at The Orion. A Bay Area transplant, he is a former pitcher, turned sports reporter.
jcouchot@chicoer.com
Follow Justin Couchot @JCouchot_Sports
Steph, Ayesha Curry oppose plan to add multi-family housing near Atherton home


text:
Q: Make an indexed hash of environment variables I have small ruby function to return a query result.  I want to check the env variables on my server so i wrote this function.  But it's not returning @result as I expected based on the puts output and the code.  What am I doing wrong?
  def query(params=nil)
    @result = {}
    count = 1
    ENV.each do |k,v|
     @result[count.to_s] = { "name" => k, "company" => v }
     puts "[#{count.to_s}] = { 'name' => #{k}, 'company' => #{v} }"
     count += 1
    end
  end

Puts output:
irb(main):070:0> query
[1] = { 'name' => ALLUSERSPROFILE, 'company' => C:\ProgramData }
[2] = { 'name' => APPDATA, 'company' => C:\Users\xxxx\AppData\Roaming }
[3] = { 'name' => CLIENTNAME, 'company' => xxxx }
[4] = { 'name' => COLUMNS, 'company' => 160 }
[5] = { 'name' => CommonProgramFiles, 'company' => C:\Program Files (x86)\Common Files }
[6] = { 'name' => CommonProgramFiles(x86), 'company' => C:\Program Files (x86)\Common Files }
[7] = { 'name' => CommonProgramW6432, 'company' => C:\Program Files\Common Files }
....

@result
irb(main):075:0> @result
=> {"ALLUSERSPROFILE"=>"C:\\ProgramData", "APPDATA"=>"C:\\Users\\xxxx\\AppData\\Roaming", "CLIENTNAME"=>"wxxxx", "COLUMNS"=>"160", "CommonProgramFiles"=>"C:
\\Program Files (x86)\\Common Files", "CommonProgramFiles(x86)"=>"C:\\Program Files (x86)\\Common Files", "CommonProgramW6432"=>"C:\\Program Files\\Common Files .....

A: use array for lists:
def query
  ENV.map {|k,v|  { "name" => k, "company" => v } }
end

@result = query

and then print it as you want.
if you really want indexed hash, use:
def query
  result = []
  ENV.each_with_index {|v,i|  result.push(i, { "name" => v[0], "company" => v[1] }) }
  Hash[*result]
end

A: Hmm, that's strange. I ran the code locally and it works as you expect it to, setting @result to something like the following...
 > @result
 => {"1"=>{"name"=>"jabjab", "company"=>"jibjib"}, "2"=>{"name"=>"blabla"...

However, I did notice that query returns the contents of environment, which is what the value of @result looks like. Is it possible that you are calling query as follow, overwriting the value of @result? This could be easily overlooked.
> @result = query

redpajama_set_name: RedPajamaStackExchange


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text:
The Paper Print Collection: How Copyright Formalities and Historical Accidents Led to Film History.
Op Den Kamp, C., 2017. The Paper Print Collection: How Copyright Formalities and Historical Accidents Led to Film History. UWA Law Review, 41 (2), 37-50.
4-Op-den-Kamp.pdf - Accepted Version
Official URL: http://www.law.uwa.edu.au/__data/assets/pdf_file/0...
Prior to the 1912 Townsend Amendment in US copyright law, motion pictures could not be registered as such for copyright protection. Seeking protection against competitors, filmmakers in the formative years of the film industry printed their films to photographic paper and deposited them for copyright as a series of individual photographs. This method of complying with a technicality in the copyright law inadvertently led to the preservation of the earliest chapter in US motion picture history, a chapter that otherwise might have been lost. The so- called Paper Print Collection, still housed at the Library of Congress, encompasses approximately 3,000 film titles. This article examines the significance of the relation between copyright, archival practices and the consequences for the study of film history. It demonstrates how (circumventions of) mandatory copyright formalities were instrumental in the safeguarding of the film titles. In turn, they played a pivotal role in the 1978 International Federation of Film Archives (FIAF) Congress in Brighton, UK, the landmark event that constituted a turning point in film historiography. An examination of the Paper Print Collection provides new insights into the relationship between copyright, registration systems, and media historiographies.
Paper Print Collection ; Library of Congress ; Copyright Mandatory Formalities
Faculty of Media & Communication


I am a graduate of the undergraduate program at the Architecture and Planning Department of the Univeristy at Buffalo. Initially drawn to the field by my interest in incorporating design and engineering, i have since become aware of the many stages of design from concept to scheme to detailing and finally to construction. Detailing in particular has become a passion as i am keenly interested in how assembly systems, facades and materials can begin to shape the built environment while simultaneously reinforcing the concepts of a design. As a recent graduate, i am seeking an internship that applies my skills in detailing, research and design in a professional environment.


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On this pack I decided to go more Eurobeat and Italo-Disco, giving it a true Retrowave feel. It's production ready and really does compliment the first pack Volume 1.There are 64 sounds across a w..
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Reveal sound's Spire is currently my favorite virtual synthesizer to use. There isn't any sound type that I haven't been able to faithfully recreate in Spire.It's capable of re..


text:
Land Donation To Bring New Soccer Complex To Liberal
KSCB News - July 25, 2016 8:49 am
The City of Liberal is proud to announce that Duane and Thelma Jean Lambert have donated a generous amount of land to assist in the construction of a new lighted city soccer complex.
"I am humbled by the extreme generosity that was shown by Duane and Thelma Jean Lambert towards our community. Duane and Thelma Jean's donation, along with efforts of the city, will benefit numerous kids and adults in our community for many years to come," Mayor Joe Denoyer said.
The two lighted soccer fields will be used by the City of Liberal for men's and women's soccer. The formation of adult soccer programs will be a new welcomed addition to the Recreation Department.
"This is a long-anticipated and exciting day for the City of Liberal, in which we will be able to offer adult soccer when the complex is completed," Commissioner Tony Martinez said. "The Lamberts have always been proud members of the Liberal, Kansas community. Mr. and Mrs. Lambert wanted to show their continued support for the people of Liberal by making a significant contribution to the community. This generous donation will be the City of Liberal's first lighted soccer fields when completed. The partnership with the Lambert's comes to life today."
The City's Recreation Master Plan includes the creation of a lighted soccer complex, as currently, the City of Liberal does not have a lighted soccer field for public use. The soccer complex will include two lighted soccer fields that can be reconfigured into four smaller fields. The City estimates that the parking lot should hold 320 cars. The lighted fields would allow for a longer soccer season. Soccer programs can be organized and held during the week in the evenings. The lighted fields would also be an impressive statement to travelers on Highway 83. The soccer complex will be located on east Tucker Road.
Construction of the new soccer complex will begin in fall of 2016 with the anticipated opening of the summer of 2017. Most of the construction will be completed by city staff as time allows.


Timber Wolf pledges to the Legion as the shuttle flies away from Raal and the evil Dr. Londo. Timber Wolf worries he can't control the beast within but Saturn girl assures him now he's a Legionnaire he'll be safe with his new friends.
Saturn Girl warns Brainiac 5 and Bouncing Boy to take it slow back to Legion headquarters as Wolf has never flown in deep space before. Help him stay calm.
Of course, the warp drive fails and the ship shudders and clutters to a halt.
Repairs underway Superman experiments with his x-ray vision and sees something heading for the ship - with lots of teeth, Brainy confirms a fleet of lunar leeches!
Worse still the entire fleet is intent on feeding, steadily draining the power of the ship!
Brainy uses his body and Lightning Lad's power to overload the ship and burn out all the leeches. As quickly as they overcome one obstacle then another arrives to test them... this time the gravitational pull of an asteroid field.
Having drained all the ship's power to get rid of the leeches the ship's generators can't power up fast enough to save them - step in the power of Superman!
Superman isn't quite graceful in the rescue attempt and shunts the crew into each other and the hull walls. Timber Wolf can't take the travel and they have to land on a nearby static asteroid so he can... bring up breakfast.
Timber Wolf wonders how he is now able to breathe in space and fly around and Brainy gloats it's his invention - the Flight Ring!
While Brainy then tends to ship repairs Saturn Girl scans the planetoid discovering a lunar leech survived! It promptly attacks the super-intelligent android and Lighting Lad and Superman are helpless to aid him - step in Timber Wolf!
He's fed up with the Legion pussyfooting and unleashes his violent animal instinct.
Destroying the leech, Wolf wonders if he's frightened his team mates. In fact it was the opposite, they were so impressed they consider him a fully-fledged Legionnaire!
Story (prior to watching the episode) - 2: Another attempt to tell a non-story where nothing happens.
It's really not good form to rely on people watching the series to enjoy the book.
The fact that there really wasn't a story is worse! It's more like twenty-two pages of deleted scenes from the Timber Wolf episode.
Art - 4: Nice artwork and much lighter inks this issue make it a nice slick issue visual wise.
Cover Art - 3: Too much text and information hides a nice image.
Shame, as it's a cool image.


The top part of this form is pre-filled using the information associated with your net-ID. If any of it is not filled, please complete it.
International Services must report the physical address of where you are living in the U.S. This must be where you live, not a post office box where you only receive mail. Please include the street address AND the apartment or room number. If you are living in a dorm, include the dorm name and your room number. If you don't know where you'll be living, enter the address of where you are staying now (for example, a hotel, a hostel, a friend's or relative's home). Immigration regulations require you to update your address within 10 days each time you move to a new residence.
We are also REQUIRED to include a U.S. phone number for you. If you do not yet have one, please include the phone number of your Cornell department or advising office.
You can access information on your arrival (called "admission") into the U.S. at www.cbp.gov/i94 OR you may have an small white card stapled into your passport at the port of entry (usually land ports only). You should print out the online admission record ("most recent entry" page) and keep it with your immigration documents.
"Admission (I-94) Record Number": 11-digit number printed on your entry record. Occasionally this has a different number of digits, and that is okay.
"Class of Admission" listed on your I-94 Admission Record: This should be F1 or J1. If you entered the U.S. in a status other than F1 or J1 (for example, B2 Tourist or B- Prospective Student or under the Visa Waiver or Global Entry Program), and you have NOT applied for a change of status, come to International Services immediately with your I-20 or DS-2019, passport, and I-94 entry record.
"Admit until Date": Does your I-94 Admission Record state "D/S"? On the line labeled "Admit until Date," your entry record should state "D/S," which stands for "Duration of Status." If your record does not state D/S, please come to International Services as soon as possible, and bring your passport and I-20 / DS-2019 with you. Note: "D/S" means that while you are a student, you are legal to remain in the U.S., provided that you comply with the regulations AND keep your I-20 or DS-2019 valid by extending it before the end date listed on your I-20 or D-2019.
In case of emergency, whom in the world should we call? This contact can be anywhere and does NOT have to be inside the U.S.
Certification: Please remember these regulations!!!!!!
Check out information about getting settled in Ithaca here.
Any Questions? Come visit us at International Services.
Always enroll FULL-TIME during the academic year (undergraduates must enroll for a minimum of 12 credit hours; graduate students must be registered full time as defined by your degree program).
APPLY FOR EXTENSION OF I-20 / DS-2019 BEFORE the end date if you need more time to complete program.
GET A TRAVEL SIGNATURE within the last 12 mos (6 mos. if Canadian or on OPT) before traveling outside of the US (page 3 of I-20, lower right of page 1 of DS-2019). Come to International Services for the travel signature (or the Cornell Tech office if you are a Cornell Tech student).
Update your LOCAL RESIDENTIAL ADDRESS within 10 days of moving by updating our online change of address form.


text:
Q: background image clipping large screens I have a div with a background image. On large screens it clips off the bottom and top. Is there a way around this without distorting the image?
.bg {
width:100%;
height:550px;
background: url(http://snorm.co/nar6336%20mar15%20v2/assets/img-dist/test.png);
background-size: cover;
background-position-x: bottom;
background-position-y: center;
}

CodePen example


Candidates for the Orange County school board are making their pitch to voters. On this episode of Intersection, we hear part of a forum recorded at Baldwin Park Elementary School in Orlando last Tuesday, where candidates talked about teacher retention and school safety.
Tariffs have businesses on edge, worried about the price on components they import, and retaliatory tariffs on things they export.
Alice Ancona with the Florida Chamber of Commerce weighs in on what tariffs mean for our $1 trillion economy, and the way forward for businesses as a trade war heats up.
And Orlando singer songwriter Luke Wagner channels the spirit of red dirt music and evokes his childhood heroes The Eagles. Wagner and violinist Tanner Johnson join us on Intersection to perform songs from Wagner's upcoming album.


text:
Inside the Manufacture
Inside The Manufacture: A Visit To Moritz Grossmann
by Rob Nudds
I was caught in the early morning foot traffic as I made my way to Dresden Neustadt train station to begin my journey back to the town that felt like a second home for three years. The busyness of the city was in stark contrast to the tranquillity I knew awaited me as I traveled closer to the home of German watchmaking. Glashütte is a tiny town, nestled in the Ore Mountains just 12 miles from the Czech border. Its association with watchmaking stretches back to the middle of the 1800s when, in 1845, Ferdinand-Adolph Lange secured backing to open his own manufacture, specializing in pocket watches. While the history of Lange himself and his company is well documented, less is known about the men that stood by his side in the early days of German watchmaking, but a modern company bearing the name of Moritz Grossmann — himself a Glashütte legend — is doing its best to change that.
The train pulled into Glashütte on time (unsurprisingly). As the station is the end of the line, every passenger alighted. Half disseminated around the town en route to their various places of work (there are more than 10 watchmaking companies still active in Glashütte) while the rest crossed the platform and boarded another train for Altenburg, a popular destination for walkers and Winter Sports fanatics. With time to spare before my meeting with Christine Hutter, CEO of Moritz Grossmann, I climbed the hill behind the massive Grossman Manufacture to sit in the shadow of the Wempe Observatory, where German timepieces are put through their paces in an attempt to earn chronometer status.
The view from the observatory belies the industry of the seemingly sleepy town. In the far distance, the sounds of the Autobahn heading north to Berlin and south to Prague drifted through the valley that time, for all its presence here, seems to have forgotten. Now, close to 30 years since reunification and the rebirth of high-end watchmaking in this area, it seems hard to imagine how close this charming enclave of horological history came to extinction. The money and prestige that watchmaking's renaissance has brought to the area have seen the town regenerate. While there is nothing in the way of nightlife to speak of, several small bakeries and cafes open throughout the day to feed and water the watchmakers, as they quietly go about their business.
As the only manufacture located on the "other side" of the train tracks, Moritz Grossmann can not help but stand out. Its towering headquarters looms over the ancient town like an avant-garde spaceship that crash-landed by accident and decided to stay. It is, without a shadow of a doubt, a physical expression of the brand's ambition. And given its CEO's background, it is not hard to see why she feels it's justified.
Officially founded in 2008, the naming rights to the company were acquired a year earlier in 2007. This was, of course, during the global financial crisis that would eventually hit the watchmaking industry a few years later. I always wondered how being born in such stormy market conditions affected the path Moritz Grossmann has traveled in its first decade of existence, assuming that the decision to trade at such an exclusive price point had something to do with the kind of customers who were not so troubled by the crashing stock-markets the world over.
But since then, the watchmaking industry has changed. While appealing to the super-rich is still a valid strategy, ensuring potential purchasers are aware of a brand and its provenance has never been more important. Reputation and heritage cannot be synthesized. Even the smartest, most astute PR team needs time to sew the seeds of trust in the minds of consumers. And although there is no shortage of money desperate to leap from customers' pockets, most of it seems to be being channeled towards "investment" pieces.
For a watch to be considered an "investment" (which is always a tricky moniker to live up to) the presence of an established brand name on the dial is often essential. Establishing a new name without a wide retail network, visible brand ambassadors, and an events budget that at least matches (or preferably exceeds) those of one's competitors is no mean feat. To find out what Moritz Grossmann is doing to ensure its future in a congested arena, I sat down with CEO Christine Hutter and Head of Communications Sandra Behrens, who kindly invited me to tour the manufacture and to ask whatever came to mind.
The first thing that strikes you when you enter the Moritz Grossmann facility is its potential. While parts of it are fully operational, there are spaces already marked for future renovation. There's a funny sense of the calm before the storm about proceedings. It is as if the many teams, furiously beavering away in silence, are conscious of and waiting for a sudden explosion. But as we know in watchmaking, suddenness is rare. In truth, the management is attempting to oversee a controlled explosion that will occur within the company's capacity so the current operation is not irrevocably destabilized in the process.
Moritz Grossman exists in one of those special watchmaking bubbles only independent brands can cultivate for themselves. The overall feel of the company is of one much smaller than it actually is, with an extreme level of care taken over the creation of each component, most of which are made on-site. As an independent company, Moritz Grossman is also able to react to individual customer desires, and, even now, consider bespoke commissions on their individual merit when requested.
The emphasis is clear: quality, quality, quality. The factory is operating well within its projected capacity. Currently, Moritz Grossman produces under 500 timepieces each year, but the plan, according to Hutter, is to increase this steadily to somewhere between an optimal output of 800-1,000 per annum. The timeframe? Around five years. The strategy? To drive attention towards an increasingly well-defined core collection with the headline-grabbing release of disruptive (and oftentimes unexpected) special editions.
With several off-the-wall limited and unique pieces over the past 12 months (such as the Super Bowl watch, the Trump meets Kim watch (which wasn't intended to send a political message of any kind, only to mark a moment in history), and a timepiece celebrating the Women's World Cup) released alongside perhaps the finest entrants in the brand's core collection to date, I wanted to know exactly why Moritz Grossmann thinks that it is necessary to release such off-brand pieces.
In contrary to the common mantra "build it and they will come" the consumer base for Moritz Grossmann's more unusual special editions is actually the driving force for their creation. At this time, at this size, the brand is still able to satisfy consumer demand by following the opposite path: "They have come, so build it we shall". Hutter is adamant that part of the brand's current appeal is that it is willing and able to respond to direct customer or regional market demand. Rather than worrying that such eccentric and esoteric releases will dilute the brand message, she is confident they will instead draw people to the brand and encourage them to explore what else it has to offer.
Intrigued, I contrasted this somewhat malleable approach with the more conservative brand-building strategies of group-owned rivals A. Lange & Söhne and Glashütte Original, and the path trodden by fellow independent NOMOS Glashütte. Hutter was quick to point out that while comparisons between Moritz Grossmann and Lange/GO were inevitable, she does not believe them to be fair, or particularly useful in ascertaining the best strategy to propel a new brand like hers forward.
The key difference, she points out, is time. A new brand like Moritz Grossmann can not, regardless of how rooted in history its story and practices may be, act like it has been around as long as the "big two" of German watchmaking. While this is true, and while it permits a little more experimentation as the brand finds its feet for the long haul, it should not be ignored that all three companies are producing luxury wristwatches in and around the same price point. It stands to reason that there will be at least some crossover between target demographics.
In this writer's opinion, that makes placing a distilled core collection front and center all the more important. And now has never been a better time to do just that. During the 1880s, Moritz Grossmann wrote a book entitled "Creating a simple, but mechanically perfect watch". Judging by the practices I witnessed firsthand, the modern-day manufacture is doing a pretty good job of living up to its namesake's guiding principles.
There is care taken in every part of the process. Two CNC machines prepare the main-plates and the bridges, crafted from German silver (an attractive, but soft and mildly reactive alloy of tin, copper, and zinc), while the wheels are cut using a long, automated machine that resembles a Gatling gun, and springs, hands, and other fine pieces are produced by electric wire cutting. Every piece is then hand finished.
Building your own gear train and other smaller pieces like springs and pinions enables a company to keep the standard of finishing very high. Hutter relayed to me a conversation she once had with Philippe Dufour, who reputedly said that only he and Moritz Grossman are finishing their wheels in between the teeth. It is this kind of attention to detail that the company's passionate CEO believes will set the brand apart. With each part created with such care, and patented quirks like the hacking mechanism that uses a small brush of human hair (normally that of Hutter herself, but could theoretically be made from anyone's hair provided they have enough to spare), or the strap winding system seen on the ladies' Twist model, the company is taking a no-holds-barred approach to novelty. But more impressive than any of these things, in my opinion, is the Hamatic movement that was premiered last year and finally released earlier in 2019. Its pendulum-inspired winding system is a thing of beauty and one of true technological marvel.
I hope, and so should all fans of German watchmaking, that these innovations and idiosyncrasies of this surprisingly charming brand are what comes to the mind first when the name of Moritz Grossmann is mentioned. And while the arresting dials of the brand's famous limited editions may command more column inches than their core counterparts, it is the unlimited models that are the real stars of the show. If the brand ever decides to produce a core steel model that strips everything back and celebrates the very foundations of the brand, with one of its classically styled German silver movements, a pared-back enamel dial, and those achingly beautiful violet/brown hands, they can put my name on the waiting list immediately. Learn more about Moritz Grossmann, and explores the brand's true character at grossman-uhren.com.
Moritz Grossmann Atum Pure M 'Mesh Dial' Watch Hands-On December 15, 2016
Moritz Grossmann Benu Enamel Watch October 31, 2017
Moritz Grossmann Benu Power Reserve Watch Hands-On July 21, 2016


text:
// ----------------------------------------------------------------------------------
//
// Copyright Microsoft Corporation
// Licensed under the Apache License, Version 2.0 (the "License");
// you may not use this file except in compliance with the License.
// You may obtain a copy of the License at
// http://www.apache.org/licenses/LICENSE-2.0
// Unless required by applicable law or agreed to in writing, software
// distributed under the License is distributed on an "AS IS" BASIS,
// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
// See the License for the specific language governing permissions and
// limitations under the License.
// ----------------------------------------------------------------------------------

using Microsoft.Azure.Commands.Relay;
using Microsoft.Azure.Management.Relay;
using Microsoft.Azure.Management.Relay.Models;
using Microsoft.Azure.Commands.ResourceManager.Common;
using Microsoft.Azure.Commands.ResourceManager.Common.Tags;
using Microsoft.WindowsAzure.Commands.Utilities.Common;
using Newtonsoft.Json;
using System;
using System.Collections;
using System.Collections.Generic;
using System.Globalization;
using System.IO;
using System.Management.Automation;
using System.Threading;

namespace Microsoft.Azure.Commands.Relay.Commands
{

    public abstract class AzureRelayCmdletBase : AzureRMCmdlet
    {
        public const string InputFileParameterSetName = "InputFileParameterSet";
        public const string SASRuleParameterSetName = "SASRuleParameterSet";
        public const string RelayParameterSetName = "RelayParameterSet";
        public const string ConsumerGroupParameterSetName = "ConsumerGroupParameterSet";
        public const string RegenerateKeySetName = "RegenerateKeySet";

        protected const string RelayNamespaceVerb = "AzureRmRelayNamespace";
        protected const string RelayNamespaceAuthorizationRuleVerb = "AzureRmRelayNamespaceAuthorizationRule";
        protected const string RelayNamespaceKeyVerb = "AzureRmRelayNamespaceKey";

        protected const string RelayWcfRelayVerb = "AzureRmWcfRelay";
        protected const string RelayWcfRelayAuthorizationRuleVerb = "AzureRmWcfRelayAuthorizationRule";
        protected const string RelayWcfRelayKeyVerb = "AzureRmWcfRelayKey";

        protected const string RelayHybridConnectionVerb = "AzureRmRelayHybridConnection";
        protected const string RelayHybridConnectionAuthorizationRuleVerb = "AzureRmRelayHybridConnectionAuthorizationRule";
        protected const string RelayHybridConnectionKeyVerb = "AzureRmRelayHybridConnectionKey";

        //AuthorizationRules
        protected const string RelayAuthorizationRuleVerb = "AzureRmRelayAuthorizationRule";
        protected const string RelayKeyVerb = "AzureRmRelayKey";

        //Parametersets for Authorizationrules
        protected const string NamespaceAuthoRuleParameterSet = "NamespaceAuthorizationRuleSet";
        protected const string WcfRelayAuthoRuleParameterSet = "WcfRelayAuthorizationRuleSet";
        protected const string HybridConnectionAuthoRuleParameterSet = "HybridConnectionAuthorizationRuleSet";

        //Parameter sets for InputObjects
        protected const string NamespaceInputObjectParameterSet = "NamespaceInputObjectSet";
        protected const string WcfRelayInputObjectParameterSet = "WcfRelayInputObjectSet";
        protected const string HybridConnectionInputObjectParameterSet = "HybridConnectionInputObjectSet";
        protected const string AuthoRuleInputObjectParameterSet = "AuthoRuleInputObjectSet";

        //Parameter sets for Properties
        protected const string NamespacePropertiesParameterSet = "NamespacePropertiesSet";
        protected const string WcfRelayPropertiesParameterSet = "WcfRelayPropertiesSet";
        protected const string HybridConnectionPropertiesParameterSet = "HybridConnectionPropertiesSet";
        protected const string AuthoRulePropertiesParameterSet = "AuthoRulePropertiesSet";

        protected struct SKU
        {
            internal const string Basic = "Basic";
            internal const string Standard = "Standard";
            internal const string Premium = "Premium";
        }

        protected struct RegeneKeys
        {
            internal const string PrimaryKey = "PrimaryKey";
            internal const string SecondaryKey = "SecondaryKey";
        }

        protected static TimeSpan LongRunningOperationDefaultTimeout = TimeSpan.FromMinutes(1);
        private RelayClient  _client;

        public RelayClient Client
        {
            get
            {
                if (_client == null)
                {
                    _client = new RelayClient(DefaultContext);
                }
                return _client;
            }
            set
            {
                _client = value;
            }
        }

        protected T ParseInputFile<T>(string InputFile)
        {
            T parsedObj;
            string path = Directory.GetCurrentDirectory();
            if (!string.IsNullOrEmpty(InputFile))
            {
                string fileName = this.TryResolvePath(InputFile);
                if (!(new FileInfo(fileName)).Exists)
                {
                    throw new PSArgumentException(string.Format(CultureInfo.InvariantCulture,Resources.FileDoesNotExist, fileName));
                }

                try
                {
                    parsedObj = JsonConvert.DeserializeObject<T>(File.ReadAllText(fileName));
                    return parsedObj;
                }
                catch (JsonException)
                {
                    WriteVerbose("Deserializing the input role definition failed.");
                    throw;
                }
            }

            return default(T);
        }
        #region TagsHelper

        public Dictionary<string, string> ConvertTagsToDictionary(Hashtable tags)
        {
            if (tags != null)
            {
                Dictionary<string, string> tagsDictionary = new Dictionary<string, string>();
                foreach (DictionaryEntry tag in tags)
                {
                    string key = tag.Key as string;
                    if (string.IsNullOrWhiteSpace(key))
                        throw new ArgumentException("Invalid tag name");

                    if (tag.Value != null && !(tag.Value is string))
                        throw new ArgumentException("Tag has invalid value");
                    string value = (tag.Value == null) ? string.Empty : (string)tag.Value;
                    tagsDictionary[key] = value;
                }
                return tagsDictionary;

            }

            return null;
        }

        public Hashtable ConvertTagsToHashtable(IDictionary<string, string> tags)
        {
            if (tags != null)
            {
                Hashtable tagsHashtable = new Hashtable();
                foreach (var tag in tags)
                    tagsHashtable[tag.Key] = tag.Value;

                return tagsHashtable;
            }

            return null;
        }

        #endregion
    }
}


Every now and then people are afraid of their websites' security. It's natural because many websites get hacked every year.
Have you ever thought to add a security question to WordPress login page? Well, this is one of the security layers you can add to your WordPress website.
For WordPress beginners, it's a challenge to harden their website security. They try seeking for the right resources but fail.
You can use two-factor authentication, password protect your WordPress admin directory, disable directory browsing and more.
In this tutorial, you will learn to add a security question to WordPress login page.
There are many websites with multiple users which can be targetted by the hackers due to the vulnerabilities. If you have a single user website then it's more important.
You may not have taken enough security actions. You may read many times about the brute force attack which are basically implemented on the login page.
Whenever you add a security plugin, you can easily see the number of fake login attempts.
That's the reason you should add an extra layer of security. Adding a security question will act like another password.
If you want to add more users then it will help you all.
The best thing about using WordPress is its plugins. To accomplish this task too, you have to use a security question plugin.
Install and activate WP Security Question plugin.
After installation, you will see a new option (WP Security Questions) in the WordPress admin panel. Open its settings and you will see the list of question you can use.
If you scroll down, you will see an option to add more questions. This is great because you can add your own security question.
And it's always recommended to use a custom question so that only you can have access to your WordPress website.
Just below it, you will see a few more options to choose the page at which you want to enable the security question.
On the login page, registration page, and password change page. The choice is yours whether you want it only on the login page or on all.
For every user, you can easily set your own question by navigating to Users>>Your Profile and scroll down.
You will see "My security question". Choose your question and enter the answer. Save the settings and you're done.
Whenever you or anyone else will try to open the WordPress login page, an extra field asking the security question will also appear.
Along with the question, fill your answer and login to your admin panel. If you have used it for your password change page then it will appear there too.
Though it's recommended to remove password lost link from your WordPress login page for security concerns but still if you keep it then don't forget to add a security question.
Depending on your settings, the question box will appear along with all the login fields.
Congrats, you have successfully added another security to your website.
Most of the beginners fret a lot which they shouldn't. You can't learn until you try. Using a WordPress plugin is easy and the plugin configuration isn't hard as it seems.
All the options mentioned in the list are the most common questions you can easily see at any membership website. Many e-commerce websites have also enabled it.
I hope it was not hard to add a security question to WordPress login page. If you still have any doubt, feel free to drop a comment.
Having an extra security level is necessary now. Like you mentioned sites are getting hacked so you have to do all you can to protect yours.
I didn't know there was a plugin to allow you to do this with ease. So know there's really no excuse why bloggers can't take their security to the next level.
Most of the bloggers think that WordPress is a complicated platform which requires experts to do these common tasks. Adding a security question isn't a hard thing.
Just the simple use of a plugin and you're done. One more security layer will get added.
I am glad that you understand the importance of security.
I am always looking for ways to harden my WordPress blog. Most people don't think about security until it's too late. As bloggers, it's important to take steps to protect our online asset.
I had no clue that you could add a security question to your blog. It's amazing, there's virtually a plugin for practically anything you can think of on WordPress.
It still amazes me that someone would even consider starting a blog on a free platform. A self-hosted blog gives you so much freedom to do anything.
I'll definitely have to check out the WP Security Question plugin. Thanks for sharing this information, I know it's going to help people secure their WordPress sites so they can feel more secure.
WordPress is a way more explored than people think. Starting a blog on the free platform can't give you enough control. You can't add such security layers.
The best thing is the plugins listed in the WordPress repository. You would love this plugin too.
Thanks for taking the time to share your words.
Superb stuff, Ravi. And on a related note, i've always wondered how to add a simple question to the registration page without a plugin. Is that even possible?
It seems that modifying said pages (login/registrations) always require plugin assistance (at least from my perspective, since im not a developer). Sometimes I feel this is a shame, as I don't want to have yet another plugin for that one single purpose.
In any case, this is a nice plugin you suggested, and quite a good alternative to standard CAPTCHAs and related methods.
You can alter the WordPres login page with codes but may block the JS and CSS which will directly show an error in the Google Search Console. There are a few things which should be done using the plugins only.
You wouldn't want to mess things up. If you don't want to use this plugin then there are many alternatives to secure your login page. You can password protected the wp-admin directory.
Ah, i hadn't quite thought about password-protecting the actual directory.
Thanks a lot Ravi, im loving your technical posts.
Is it possible to do this without installing WP security question plugin? Adding more plugins will make the site more vulnerable?
As I have told Elvis, adding a security question is possible with a plugin for now. But you can do other things to add the security layers. You can add two-factor authentication without a plugin and with a plugin.
You can restrict the email login and a few other things.
That's superbly nice addition I can have on my login page!
I know this is the most-needed function and I am glad you covered this sensitive topic as you know, the security is the mess in these days.


text:
Reggie Hayes Bio, Net Worth, Wife, Now, Girlfriends and Career , Age, Height,
Reggie Hayes Biography
Reggie Hayes is broadly known as an American entertainer, screenwriter, and chief, who is most popular for his person as William Dent on the UPN/CW show, Girlfriends.
Haye was conceived Reginald "Reggie" C. Hayes in Chicago, Illinois—most youthful of four kids. Reggie went to St. John's Northwestern Military Academy, which remembered him as one of three "Eminent Men of the Academy".
After the Academy, Reggie went to Illinois State University, where he acquired a four year certification in Theater. In 2004, he won the "Remarkable Young Alumni Award" and was an individual from the Illinois Shakespeare Festival.
Reggie Hayes Net Worth
Hayes has currently an expected total assets of $4 million dollars
Reggie Career
Reggie is an enthusiastic ally of his local area and worked close by his sister at different occasions for a foundation named the "Reginald and Frances Hayes H.O.P.E. Grant Award".
Reggie is most popular for his person as William Dent on UPN/CW's hit TV show Girlfriends that circulated for a very long time, finishing in 2008. It got him the "Best Supporting Actor in a Comedy Series" for three NAACP Image Awards. Reggie proceeded to show up in a few different films and TV shows, including Criminal Minds, Will and Grace, and NCIS.
After a short vocation break, Reggie collaborated with Lock and Key Entertainment.
Reggie Hayes Age
Reggie is currently 52 years, he was brought into the world on July 15, 1969, in Chicago, Illinois, United States.
Reggie Hayes Height and weight
Reggie remains at a stature of 5 feet 7 inches (1.73 m) tall and has a weight of 60kg.
Reggie Parents
Reggie was brought up in Chicago, Illinois by his parents Frances (mother) and Reginald Hayes. Reggie is the most youthful of four kids.
Hayes Wife
Information about his love life is currently unknown. We will soon update this section once we have the details.
Reggie Girlfriends
Reggie is most popular for his person as William Dent on UPN/CW's hit TV show Girlfriends that broadcasted for a very long time, finishing off with the year 2008. Reggie's sweetheart isn't freely known, he is right now single.
Tati Gabrielle Bio, Net Worth ,Age,The 100, Height, Parents, Husband,
Brianne Howey Bio, Age, Husband, Family, Net Worth, Time Trap and The Passage
Ranjeet Singh Dehal Bio, Age, Family, Ranvir Singh, Net Worth and Job
Rae Burrell Biography, Salary and Net Worth ,Age, Height, Boyfriend
Director Entertainer
Celebrrity spouse
Basketballer


text:
Исаа́к Петро́вич Шмару́к (; 1910 — 1986) — украинский советский кинорежиссёр.

Биография
Родился 9 (22 августа) 1910 года в Нежине Черниговской губернии, Российской империи, ныне Черниговская область, Украина).
Окончил факультет режиссуры киноинститута в Киеве (1934). Работал на киностудии имени А. П. Довженко в Киеве.

Умер 2 августа 1986 года. Похоронен в Киеве на Байковом кладбище.

Фильмография

  — Украденное счастье (фильм-спектакль)
  — Судьба Марины
  — Звёзды на крыльях
  — Без вести пропавший
  — Правда
  — Млечный Путь
  — Сейм выходит из берегов
  — Фараоны (фильм-спектакль)
  — Бесталанная (фильм-спектакль); Почему улыбались звёзды (фильм-спектакль)
  — Свадебные колокола
  — Рассказы о Димке (новелла «Димка-велогонщик»)
  — Мир хижинам, война дворцам
  — Второе дыхание
  — Вера, Надежда, Любовь
  — Простые заботы
  — Голубые молнии
  — Казнить не представляется возможным
  — Твоё мирное небо

 Награды
 1954 — номинация на Гран-при 7-го Каннского кинофестиваля («Судьба Марины''»)

Примечания

Члены Союза кинематографистов СССР
Персоналии:Киностудия имени А. Довженко
Похороненные на Байковом кладбище


Frank: Communication is critical in lawsuits – to communicate with your clients, to keep them informed, to understand what's important to them, to understand what they are not understanding. Other than seeing it on TV or in the movies, people don't really know what to expect. This is the one day that they have or the one trial that they have, so it's important to understand why things are happening the way that they're happening. Klein: The first thing that I think it important in a client relationship is to have trust. When I have those relationships with clients, I can let them be fully self-expressed. When they're that way, that's the most powerful and that's when juries want to help them the most. Frank: It's important equally to communicate with the other side. You want to be sure that your motion is written in a way that the judge understands; then they can rule in your favor. Communication is an aspect from beginning to end in these cases.


text:
SZA's 'SOS' Spends Most Weeks At No. 1 For An R&B Album Since Usher's 'Confessions'
By: Yohance Kyles (@HUEYmixwitRILEY)Category: News January 24, 2023
The TDE singer/songwriter continues to dominate the Billboard 200 chart.
Every week SZA cements her name in the record books next to R&B legends thanks to her critically-acclaimed SOS studio LP.
Last week, SZA reached the 1990s-era Billboard 200 chart milestones of notable performers TLC and Mariah Carey. This week, the Top Dawg Entertainment songstress achieved a feat not seen since Usher Raymond in the mid-2000s.
SOS remained atop the most recent Billboard 200 rankings for a sixth consecutive week. SZA became the first R&B act, male or female, to control that album chart at least six times since Usher's 2004 classic Confessions.
SZA will have to place in the pole position three more times to accomplish the nine-nonconsecutive-week reign of Confessions. She already matched the last time a female R&B singer pulled off a six-week run at No. 1 – Carey's Daydream in 1995/1996.
SOS OUT NOW https://t.co/LQNd1Ny0iy pic.twitter.com/hWVKTU3jfh
— SZA (@sza) December 9, 2022
In addition, SOS is the first female R&B album to spend its first six weeks at No. 1 since Janet Jackson's janet thirty years ago. SZA also joined Adele and Taylor Swift as the only women to have an album spend at least six weeks at No. 1 in the last thirteen years.
SOS brought in additional 119,000 equivalent album units in week six of its release. The SOS track "Kill Bill" is also performing well on the Billboard Hot 100. "Kill Bill" has already peaked at #2 on that weekly chart.
SZA earned her first Number One on the Billboard 200 with SOS. Previously, the New Jersey native made it to No. 3 with 2017's Ctrl. The 33-year-old vocalist's 3x-Platinum debut album has remained on the Billboard 200 for over 290 weeks.


text:
type: doc
layout: reference
category: "Syntax"
title: "Returns and Jumps"
---

# Returns and Jumps

Kotlin has three structural jump operators

* *return*{: .keyword }. By default returns from the nearest enclosing function or [anonymous function](lambdas.html#anonymous-functions).
* *break*{: .keyword }. Terminates the nearest enclosing loop.
* *continue*{: .keyword }. Proceeds to the next step of the nearest enclosing loop.

## Break and Continue Labels

Any expression in Kotlin may be marked with a *label*{: .keyword }.
Labels have the form of an identifier followed by the `@` sign, for example: `abc@`, `fooBar@` are valid labels (see the [grammar](grammar.html#labelReference)).
To label an expression, we just put a label in front of it

``` kotlin
loop@ for (i in 1..100) {
    // ...
}
```

Now, we can qualify a *break*{: .keyword } or a *continue*{: .keyword } with a label:

``` kotlin
loop@ for (i in 1..100) {
    for (j in 1..100) {
        if (...) break@loop
    }
}
```

A *break*{: .keyword } qualified with a label jumps to the execution point right after the loop marked with that label.
A *continue*{: .keyword } proceeds to the next iteration of that loop.

## Return at Labels

With function literals, local functions and object expression, functions can be nested in Kotlin.
Qualified *return*{: .keyword }s allow us to return from an outer function.
The most important use case is returning from a lambda expression. Recall that when we write this:

``` kotlin
fun foo() {
    ints.forEach {
        if (it == 0) return
        print(it)
    }
}
```

The *return*{: .keyword }-expression returns from the nearest enclosing function, i.e. `foo`.
(Note that such non-local returns are supported only for lambda expressions passed to [inline functions](inline-functions.html).)
If we need to return from a lambda expression, we have to label it and qualify the *return*{: .keyword }:

``` kotlin
fun foo() {
    ints.forEach lit@ {
        if (it == 0) return@lit
        print(it)
    }
}
```

Now, it returns only from the lambda expression. Oftentimes it is more convenient to use implicits labels:
such a label has the same name as the function to which the lambda is passed.

``` kotlin
fun foo() {
    ints.forEach {
        if (it == 0) return@forEach
        print(it)
    }
}
```

Alternatively, we can replace the lambda expression with an [anonymous function](lambdas.html#anonymous-functions).
A *return*{: .keyword } statement in an anomymous function will return from the anonymous function itself.

``` kotlin
fun foo() {
    ints.forEach(fun(value: Int) {
        if (value == 0) return
        print(value)
    })
}
```

When returning a value, the parser gives preference to the qualified return, i.e.

``` kotlin
return@a 1
```

means "return `1` at label `@a`" and not "return a labeled expression `(@a 1)`".


Human resources are like natural resources; they're often buried deep. You have to go looking for them, they're not just lying around on the surface.
"Bring on the Learning Revolution!" TED2010. Feb. 2010. Conference Presentaion.
Source: "Bring on the Learning Revolution!" TED2010. Feb. 2010. Conference Presentaion. Additional Information: This quote by creativity expert Ken Robinson means that human resources, i.e., one's natural talents, are often hidden and difficult to unearth, just like the valuable oil underneath the earth's service. The problem, says Robinson, is that education doesn't create the circumstances, or the necessary tools, needed to reveal these resources. According to Robinson, we need an education revolution so that people can get in touch with their natural gifts and go on to have more fulfilling careers. The quote is from Robinson's 2010 TED Talk. Watch the full TED Talk here: Ken Robinson - Bring on the Learning Revolution!


People arrive at having an ostomy in such a variety of ways, each having their own unique story. Recently I've been fortunate to spend time in the company of a group of people all of whom have an ostomy and we are all so different, yet also have this one thing in common.
There is nothing that would have prepared me for surgery. In fact I think if I'd known then what I know now it would have been a tougher decision. But the right one nonetheless.
The reality is no one would choose to have an ostomy, to deal with the loss of their intestines, to poop into a bag stuck to their body. Except I did choose. I chose to lose my colon rather than continue to hammer my body with drugs that my body wasn't responding to anyway, to have continued active bowel disease, to wait for cancer or to further compromise my immune system and tax my body and organs. That route had an inevitability to it that didn't end well so whilst surgery isn't easy to opt for it was something of a no brainer (for the logical part of my brain anyway).
There are times when I reflect back on life before surgery, particularly 2016, which I lost entirely to being unwell. The thing that hit me hardest when relapsing was the isolation. The nature of bowel disease means that when you're at your worst you are completely alone, sometimes for hours a day. I was confined to the bathroom, in intense pain, with diarrhoea and bleeding and it was utterly exhausting. In 2016 before I became too unwell to travel to work I spent stressful journeys on the train, trying to keep calm and not let my face betray what was really going on as I counted the minutes and seconds until I could get to the station toilets. Inevitably I would find myself sending emails from the toilet at the station or at work apologising for not being where I was meant to be whilst trying to cover the reason. As if that's not stressful enough starting the day exhausted, putting on my best game face and negotiating work activities in the process all the while hoping I would be well enough to get through the day.
Yes having your colon removed is life changing and in ways I never comprehended. It has touched every aspect of my life and now I'm putting it back together again. There are days that are harder than others but in fact life with my ostomy is good. I have weight to lose (gained through months on steroids) and have to get back to physical fitness (I love training for strength and can't wait to be able to workout regularly again). The main challenges for me at the moment are some legacy health issues along with some new and emerging ones. I'm still in a much improved situation compared to last year and it's my belief that I will be able to manage these and go on to live a full and 'normal' life.
So why surgery? I think the above says it all!