text:
Drug Metab Dispos. 2017 05; 45(5):457-467.DM
Common marmosets (Callithrix jacchus), small New World primates, are increasingly attracting attention as potentially useful animal models for drug development. However, characterization of cytochrome P450 (P450) 3A enzymes involved in the metabolism of a wide variety of drugs has not investigated in marmosets. In this study, sequence homology, tissue distribution, and enzymatic properties of marmoset P450 3A4 ortholog, 3A5 ortholog, and 3A90 were investigated. Marmoset P450 3A forms exhibited high amino acid sequence identities (88-90%) to the human and cynomolgus monkey P450 3A orthologs and evolutionary closeness to human and cynomolgus monkey P450 3A orthologs compared with other P450 3A enzymes. Among the five marmoset tissues examined, P450 3A4 ortholog mRNA was abundant in livers and small intestines where P450 3A4 ortholog proteins were immunologically detected. Three marmoset P450 3A proteins heterologously expressed in Escherichia coli membranes catalyzed midazolam 1'- and 4-hydroxylation, alprazolam 4-hydroxylation, nifedipine oxidation, and testosterone 6β-hydroxylation, similar to cynomolgus monkey and human P450 3A enzymes. Among the marmoset P450 3A enzymes, P450 3A4 ortholog effectively catalyzed midazolam 1'-hydroxylation, comparable to microsomes from marmoset livers and small intestines. Correlation analyses with 23 individual marmoset liver microsomes suggested contributions of P450 3A enzymes to 1'-hydroxylation of both midazolam (human P450 3A probe) and bufuralol (human P450 2D6 probe), similar to cynomolgus monkey P450 3A enzymes. These results indicated that marmoset P450 3A forms had functional characteristics roughly similar to cynomolgus monkeys and humans in terms of tissue expression patterns and catalytic activities, suggesting marmosets as suitable animal models for P450 3A-dependent drug metabolism.
Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan (S.U., K.N., S.I., H.Y.); Pharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd., Kainan, Wakayama, Japan (Y.U.); Department of Applied Developmental Biology (T.I.), and Center of Applied Developmental Biology (E.S.), Central Institute for Experimental Animals, Kawasaki, Japan; and Keio Advanced Research Center, Keio University, Minato-ku, Tokyo, Japan (E.S.).
Nakanishi K
Ishii S
Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan (S.U., K.N., S.I., H.Y.); Pharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd., Kainan, Wakayama, Japan (Y.U.); Department of Applied Developmental Biology (T.I.), and Center of Applied Developmental Biology (E.S.), Central Institute for Experimental Animals, Kawasaki, Japan; and Keio Advanced Research Center, Keio University, Minato-ku, Tokyo, Japan (E.S.) hyamazak@ac.shoyaku.ac.jp.
AdolescentAdultAgedAlprazolamAnimalsCallithrixCytochrome P-450 CYP3AFemaleHumansIntestine, SmallLiverMacaca fascicularisMaleMicrosomesMidazolamMiddle AgedMultigene FamilyNifedipinePharmaceutical PreparationsPhylogenySequence AlignmentSequence Homology, Amino AcidSpecies SpecificityTestosteroneYoung Adult
Uehara, Shotaro, et al. "Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone." Drug Metabolism and Disposition: the Biological Fate of Chemicals, vol. 45, no. 5, 2017, pp. 457-467.
Uehara S, Uno Y, Nakanishi K, et al. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone. Drug Metab Dispos. 2017;45(5):457-467.
Uehara, S., Uno, Y., Nakanishi, K., Ishii, S., Inoue, T., Sasaki, E., & Yamazaki, H. (2017). Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone. Drug Metabolism and Disposition: the Biological Fate of Chemicals, 45(5), 457-467. https://doi.org/10.1124/dmd.116.074898
Uehara S, et al. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone. Drug Metab Dispos. 2017;45(5):457-467. PubMed PMID: 28196829.
TY - JOUR T1 - Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone. AU - Uehara,Shotaro, AU - Uno,Yasuhiro, AU - Nakanishi,Kazuyuki, AU - Ishii,Sakura, AU - Inoue,Takashi, AU - Sasaki,Erika, AU - Yamazaki,Hiroshi, Y1 - 2017/02/14/ PY - 2016/12/29/received PY - 2017/02/10/accepted PY - 2017/2/16/pubmed PY - 2017/8/26/medline PY - 2017/2/16/entrez SP - 457 EP - 467 JF - Drug metabolism and disposition: the biological fate of chemicals JO - Drug Metab Dispos VL - 45 IS - 5 N2 - Common marmosets (Callithrix jacchus), small New World primates, are increasingly attracting attention as potentially useful animal models for drug development. However, characterization of cytochrome P450 (P450) 3A enzymes involved in the metabolism of a wide variety of drugs has not investigated in marmosets. In this study, sequence homology, tissue distribution, and enzymatic properties of marmoset P450 3A4 ortholog, 3A5 ortholog, and 3A90 were investigated. Marmoset P450 3A forms exhibited high amino acid sequence identities (88-90%) to the human and cynomolgus monkey P450 3A orthologs and evolutionary closeness to human and cynomolgus monkey P450 3A orthologs compared with other P450 3A enzymes. Among the five marmoset tissues examined, P450 3A4 ortholog mRNA was abundant in livers and small intestines where P450 3A4 ortholog proteins were immunologically detected. Three marmoset P450 3A proteins heterologously expressed in Escherichia coli membranes catalyzed midazolam 1'- and 4-hydroxylation, alprazolam 4-hydroxylation, nifedipine oxidation, and testosterone 6β-hydroxylation, similar to cynomolgus monkey and human P450 3A enzymes. Among the marmoset P450 3A enzymes, P450 3A4 ortholog effectively catalyzed midazolam 1'-hydroxylation, comparable to microsomes from marmoset livers and small intestines. Correlation analyses with 23 individual marmoset liver microsomes suggested contributions of P450 3A enzymes to 1'-hydroxylation of both midazolam (human P450 3A probe) and bufuralol (human P450 2D6 probe), similar to cynomolgus monkey P450 3A enzymes. These results indicated that marmoset P450 3A forms had functional characteristics roughly similar to cynomolgus monkeys and humans in terms of tissue expression patterns and catalytic activities, suggesting marmosets as suitable animal models for P450 3A-dependent drug metabolism. SN - 1521-009X UR - https://www.unboundmedicine.com/medline/citation/28196829/Marmoset_Cytochrome_P450_3A4_Ortholog_Expressed_in_Liver_and_Small_Intestine_Tissues_Efficiently_Metabolizes_Midazolam_Alprazolam_Nifedipine_and_Testosterone_ L2 - http://dmd.aspetjournals.org/cgi/pmidlookup?view=long&pmid=28196829 DB - PRIME DP - Unbound Medicine ER -
Callithrix
Cytochrome P-450 CYP3A
Microsomes
Multigene Family
Sequence Alignment
Sequence Homology, Amino Acid
Species Specificity
Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers.
Oxidation of R- and S-omeprazole stereoselectively mediated by liver microsomal cytochrome P450 2C19 enzymes from cynomolgus monkeys and common marmosets.
In vivo and in vitro diclofenac 5-hydroxylation mediated primarily by cytochrome P450 3A enzymes in common marmoset livers genotyped for P450 2C19 variants.
Survey of Drug Oxidation Activities in Hepatic and Intestinal Microsomes of Individual Common Marmosets, a New Nonhuman Primate Animal Model.
Functional characterization and tissue expression of marmoset cytochrome P450 2E1.


text:
So, I had all these posts started a while back before work got really bad, so you're getting some "historical treats" now.... I have a stitch weekend coming up (huzzah! No work on Friday!), so expect a brief silence followed (hopefully soon) by lots of eye candy.
About two weeks after I started working full-time again, I had a sense of deja-vu. It had nothing to do with long hours or eating takeout for every meal or feeling like cleaning and laundry were an endless cycle squeezed into spare moments. It had to do with shopping. Working full-time and not having any time for hobbies, for some reason, makes me want to buy stuff. Real bad.
It started innocently enough...my old Roomba was dying a slow, pitiful death, and now I don't have time to fiddle with it or dust-mop myself. Plus, I had walked past a Brookstone a few weeks before and heard the dulcet purr of the new model (as compared to the unwieldy screech mine was making)...so much quieter than previous models. So, I headed to Linens 'n' Things with my 20% off coupon, and procured Dusty II:
But the hankering for new gadgets did not stop there. I have a coworker who is a compulsive hummer. This person will hum tunes, or tunelessly, or mutter, "OhhhHHHhhh..." throughout the day and it drives me BATTY. I have been unable to come up with a tactful way to address this, so, as any logical person would decide, I must have an iPod instead. Once my heart was set on the blue nano (sooo cute!), I discovered blue was only available in the expensive high-capacity version. *sigh* A few days later, woot.com came to my rescue with a refurbed one even cheaper than the silver-only smaller model. I've included items for scale so that everyone should be able to grasp its wee cuteness:
And the best thing? Oh, yeah, it's right there on the screen...I can now watch LOST video podcasts!! I must also point out that above the teensy iPod is a weensy bamboo crochet hook I procured at Knitch. Perfect for slipping in the sock-on-the-go bag. And it was only 2 smackers!!
The other big purchase was a recliner. Now, I never thought that Michael's design sensibilities would ever allow a recliner into our home until he was a few decades older and comfort considerations overrode his aesthetic objections. Me, I didn't care too much either way, having lived with a dad who was seldom out of his big ugly chair. Before I met Michael I wouldn't have thought it possible that a man could exist without a recliner. Anyway, we went to ADAC's annual sample sale (home of the $50 dupioni silk comforter and shams from last year) and scored this awesome leather recliner that actually manages clean lines in the midst of its insane comfort:
Finally, I give you the frog:
This purchase did not require a major investment, but I love the way he looks with our alebrijes. He comes fresh from causing an uproar at the Atlanta Downtown Tour of Lofts and Lifestyles street market. The sweet old Southern gentleman presiding over the booth that had frogs, frogs, and more frogs (along with a couple of grasshoppers) explained all about how to gently drag the stick (pictured in the frog's mouth) over the ridges on his back to mimic a croaking sound. There were BIG frogs that sound like bullfrogs, medium frogs (like this guy) that sound like garden frogs and tiny frogs that sound like tree frogs.
Michael and I were fascinated and spent a long time choosing the tone and paint job we liked best. We would have probably gone for a bullfrog if there'd been a paint job that spoke to us like this one. Anyway, in the midst of our testing, and retesting, this guy stops about 10 feet away on my right cocks his head and says, "If you do that one more time, I'm going to have to take it away."
I give him my standard response to awkward social situations, which is to smile, giggle, and ignore him as I continue with what I was doing. He says again, "I am serious. That is really annoying. That frog is, like, getting on my nerves. It is like...." Here he pauses for a moment, rolls his eyes back, and his head begins to shake as if he has his phone on vibrate and for some reason has strapped it to his head. It's a little disturbing, to say the least.
Did I mention we were at an outdoor market? A public, outdoor market? Dude...walk away if you don't like it. He continues ranting for a couple minutes more, as I stare at him, waiting for him to just walk away already. Being that the artist who made the frog is standing right there, crazed homeless guy is being, like, really rude in what he's saying.
Sorry. I should be fair. He was not necessarily homeless. He could have been one of those guys that pretends to be homeless so he can scam a couple bucks toward the beer fund until the next pay day. (Yes, this has actually happened. You learn things when you live downtown.)
Anyway, he finally moves on, but not two minutes later, a guy comes right up to my shoulder and says practically in my ear, "If that were in my house, that would look like a really great chew toy for my dog."
My defensive giggle doesn't even kick in as I stare at him, aghast. Instead, he giggles manically towards his other stylish friends and mercifully continues on his way. I turn to the artist (who is now looking distinctly annoyed despite his good manners and restraint) and say, "Well, there's at least two people here that I wouldn't invite to my house!"
Every Stimulus has a Reaction....
Labels: hypurlbolics, lofty lives, ramblings, small screen
Ornamental June
I never did a report on my stitching for Ornamental June (stitching on ornaments from Just Cross Stitch Ornament issues). I did finish one ornament, Poinsettia by Britty Kitty from the 2007 issue (for this year's exchange):
I hope to have it "ornamentified" before the exchange on Friday!! I can't believe how dark the red for this is (it's Cinders by GAST). It's nearly black!
I also worked on a Wee Works ornament...I can't remember the name, but it's stitched on three cards of Tokens and Trifles Bon Bon cards. I'm on the first one... *sigh* I don't have that much progress to show from last month, but I've designated it my travel project for the month, since it includes red and white.
I finally finished my surprise ornament for the exchange, also (it's even ornamentified!)...but I can't show it to you until after the exchange!! I'm rather pleased with how it turned out, and it represents a "first" for me, so I can't wait to show it off!
What month is it again??
The Chronicles of WALL-E: Speed Panda and the Iron Skull
One thing I love about summer is summer movie season. So far this season, we've seen
The Chronicles of Narnia: Prince Caspian
Kung-Fu Panda
Given this list, I would have expected to enjoy WALL-E, Indiana Jones and Prince Caspian the most, and Ironman and Kung-Fu Panda the least. In truth, it was almost the opposite. Notice, I said enjoy. This does not mean Kung-Fu Panda is a "better" movie than, say, Prince Caspian. We're talking enjoyment. And hopefully, that's what you'll get from my mini-reviews....
I had no desire to see this movie. Although I'm a minor superhero fan, I didn't grow up reading DC and Marvel comic books, so I didn't really know Ironman's story. I could have picked him out of a lineup (even a lineup that included other superheroes...because, you know, otherwise the suit would have been a dead giveaway) and that's about it. Couldn't have told you his "real" name. Couldn't have made a single guess at his origin story. Couldn't have drawn one line to him on the "match the superhero to the supervillain" worksheet. But after a couple good reviews from people I trust, who have rather disparate movie tastes, I became fascinated. How could both these people like this movie?? Well, I'm here to tell you, it is good. Just as good as they'd said. Robert Downey, Jr., is brilliant as Tony Stark. Gwyneth is brilliant as well (although we'll just leave her character name out of it. Pur-lease, who comes up with these???) SFX: great. Story: great. The only major objectionable content is a reporter who badgers Tony about his scruples and turns out to have none of her own. But as it plays to his character arc, and sets up such a fabulous scene for Gwyneth, it gets a pass. Just know if you're taking a teenage boy, you might need to have a brief eye-covering in there. It's incredibly violent. But I think I was most gratified that nowhere in the movie did Ironman say, "Can't we all just get along?" It was clear that, no, they couldn't. So by golly, let's defend the innocent against the guys with big guns rather than blather on at them with words they can't hear, anyway, for the rat-a-tat-tat of their machine guns. I loved it.
I heard one reviewer say that watching this movie was like being hit in the head with a pack of Starburst. Sugar fiend that I am, I loved it. I enjoyed the cartoon (though I was not a superfan), and I was hoping the Wachowski brothers would create a great look for it. I think they succeeded. The race sequences were brilliantly conceived. At first, I was taken aback by the fact that it wasn't "regular" racing...the tracks are more like roller coaster tracks, and a "jump" button on the cars is standard. But then I realized that they needed to "plus" the racing experience, and this was a great and fun way to do it. The movie has some very funny moments, and it's all about family, so what's not to like? Not to mention Matthew Fox in leather...and doing kung-fu...how can you say "no" to that??
I liked about half of this movie. Not the first half, nor the last half, nor the half in the middle. I liked the half that stuck to the book plot. The half I didn't like was where Peter was going through the same exact character journey he went through in the first movie ("Gee, I have to lead a bunch of people! Maybe I'll be a total jerk about it! Well, that didn't work too well....") and Susan was succumbing to hormones. Once again, my favorite character ended up being Edmund. I can't wait to see what Skandar does when he's older...hopefully he does some good films and doesn't become too "arty" like Dan Radcliffe ("Eq! Eq!") The interaction between the brothers was priceless. My least favorite part of the movie (and this will only be a spoiler if you've recently read the book) was when they introduced a plot point that C.s. Lewis has Reepicheep suggest as a viable option, merely to show Reepicheep's chivalry-over-reality character trait. "Hey, a mouse suggested this campaign that's doomed to fail! Let's put that in the movie!" Reepicheep, on the other hand, though not perfect to my vision, was great.
I've now seen this twice, since we took Michael's dad for Father's Day. I enjoyed it much more the second time around, although the plot holes gaped wider. The good: Harrison Ford cannot help but be charming as Indy, and Shia LaBeouf is great. He's fast becoming one of my favorite young actors, probably because of his subtle grasp of comedy. Also good: The best introduction to "what time period are we in again?" ever. The bad: Remember, according to Spielberg & Lucas, Indy is an archaeologist who hunts down artifacts with a supernatural bent. I often forget that last part and think only of adventures. But you're a little more slapped in the face with it in this movie. Turn brain off and try not to make sense of it, 'cause the sense ain't there for you to find. The ugly: An homage to Tarzan, or just random swinging through the trees with monkeys? You decide.
By all rights of taste, I should not be a Jack Black fan. But yet, I am. The man makes me laugh. Now, granted, I have not seen most of his movies. But School of Rock? That's the funny, dude. And the funny continues in this movie. JB is at his comic timing best, and the supporting cast is awesome, though seriously under-used. I didn't even realize Viper was voiced by Lucy Liu until the end credits! Which, by the way, are worth staying for. They're not as flat-out awesome as the opening credits, which rock in stereo, but still worth it. I went to see this movie based on good reviews, since I am not, in general, a DreamWorks Animation fan. They tend to do things on the cheap, and it shows. Kung-Fu Panda is an exception to that rule, though. The character animation is probably the best they've done. And, you are in for possibly the best fake-out moment in all of cinema. Seriously.
This was probably my most-anticipated movie so far...even more than Caspian or Indy. I mean, is there any way I wouldn't enjoy a Pixar movie? I laughed my head off during the short at the beginning and settled in for the main event. The graphics blew me away. I remember during previous movies periodically telling myself, "This is CG!!" During this first half of this one, it was more like I completely forgot about it and there were a couple distinct moments where something made me remember. It was shocking...in a good way. The movie was engrossing, but afterwards, I felt vaguely uncomfortable. I LOVED the story, but I wasn't sure if an insidious environmental agenda was being pressed on me. Kind of "An Inconvenient Robot"...until I read this interview with Andrew Stanton, the director (WARNING: this article contains spoilers!). Without being spoilericious: If all your needs were fulfilled, what would happen to your relationships with others? Environmentalism shoved down my throat? No, thanks. Caring more about others than your own selfish desires? Now there's a message I can get behind.
More excitement than you can shake a Pixy Stick at.
Labels: flicks
Decked out
The next morning after we saw the first hibiscus bloom, we awoke to this:
Fortunately, that was, as you can see, in the daylight. No more neighbor troubles at this time. She has been home, but she's been quiet! Thank you for all the well wishes and commiserations.
I was most disturbed when Michael told me he saw a cat in our neighbor's window! Actually, I think it looked more like this. Our 4th of July party briefly considered a cat rescue mission.
I wish I'd put my hand in one of these pictures...the flowers are HUGE! The only downside to these beauties is that they only last a day, and by the evening, having endured a warm wind all day, their petals are flowing with the breeze like the skirts of a swaying dancer. These are actually Swamp Hibiscus...although the name sounds awful, it just means that while they love bright, direct sun (a must for our deck), they drink water like fish! They even love to be planted directly in water.
But you want to see the rest of the deck! Here's the view from our deck door:
We got the great pots at No Mas! Productions and thought they were a perfect size. Then we went to Pike Nursery. We had talked to a lady there who has done lots of urban decks, and she had advised us to pick pots first. Unfortunately, she wasn't around when we first got there. Another lady tried to help us, but she kept telling us that our pots were too small for everything we wanted. When we would finally pick out something that would "fit", we'd say, "Well, what else can we add?" And she'd say, "Oh, no...that's going to take up the whole pot. Your pot is really not that big." OK, lady, we get that, but what about the store display of container gardening we're standing by that has three plants this size in a smaller pot than ours??? We couldn't make her understand. Fortunately, she finally left us alone (out of frustration, I think), and our original helper showed up. It only took her about 10 minutes to help us pick all these plants! And you should have heard her telling me to "mush" the Creeping Jenny in with the hibiscus! The other lady would have fainted! She was definitely all about the plants...it was more important that the plants be happy than us, LOL!!
Closeup of the first pot...
...and some of its residents. This is an Egyptian Starflower (or pentus), just in front of Quicksilver (or Silver Shield). It's insane how much the Quicksilver has grown since this picture!
These are the fan flowers, behind which you can just make out the Mexican Heather. It has doubled in size since this picture, but it's still dwarfed by the other plants, which have just taken off! I'll have to move it to a different pot next year. Um, if it's an annual. Excuse my "new gardener" ignorance, but I can't even remember what's an annual at this point!
Moving from here around the deck towards the hibiscus...which, by the way, is skirted by Creeping Jenny and its wonderful electric greenery...
We encounter one of our more "succulent" pots. At least, the Ice Plant (with the pink flowers) and the euphorbia splurge are. We thought the Medusa Rush was as well...but...we've lost a lot of it because we didn't give it enough water. I should have recognized it as being similar to the grass that used to grow around the lake where I grew up. There are two pots like this, and two of the hibiscus...
...but the sixth pot is a little different. While it does contain some Quicksilver and fan flowers, instead of another Egyptian Starflower, it has some Angelonia instead. I love the Angelonia, and it's been blooming constantly!!
And look what else "grew" while I've been away!
These are the Pomatomus socks (or Hippopotamus socks, as DF Jill calls them...because I could never pronounce them right!), knit it Knit Picks Dancing (sadly, discontinued). If I had them to do over again, I'd probably add a half a repeat to the leg length. I did only two instead of three, because with my short legs I thought they'd be too long. They're knit top down, though, so I couldn't try them out except by holding them up to my leg. They really stretch wider/shorter when you put them on, though, so I might have been OK with three repeats. The pattern didn't make "sense" to me until the first repeat of the second sock. Before that, it was a super-tedious chart-reading exercise. After, it was like, Duh! These are definitely not beginner socks, but they could be accomplished by anyone who's knit a pair before. After all, they're my second pair. =)
I came, I planted, I knit. The deck looks exactly like a tropical paradise now. Well, not exactly.
Labels: hypurlbolics, lofty lives
Lost Weekend
This was meant to be a post showing all my pretty deck plants. It was meant to have been posted last Sunday, after chores were done Saturday, the 4th was all planned for, and I was rested and relaxed. Instead, I give you the following epic saga:
Friday night, 1am - Heather and Michael trundle off to bed, exhausted from the week but looking forward to getting a lot of rest and a weekend of many chores, followed by much relaxation.
2:43am - Heather is rocketed out of a deep sleep by music from the neighbor (who shares a wall, and who we have attemped repeatedly to meet). You know how when you're asleep, and a noise starts, and it sort of gradually works its way into your dream until you eventually wake up? This is not one of those times. The sound level is vaguely what you'd experience if you went into the bathroom of one of those clubs where you cannot actually talk to anyone because the music is so loud.
2:49am - Michael is woken by Heather. He's a much sounder sleeper.
3:20am - Consciousness and gross disbelief have finally reached the level where action is incumbent. Michael goes downstairs to try and find something to bang on the wall with that will 1) be loud enough to be heard above the cacophony and 2) not damage the wall in the process.
3:31am - Heather decides banging on her door would be a better idea and dons clothing.
3:32am - Michael presents his belief that he is not capable of calm, lucid, and, especially, calm discourse with the neighbor.
3:33am - Heather bangs on the neighbor's door. Repeatedly.
3:35am - Between banging, Heather hears a smoke detector beeping as if its battery needs to be changed. This is unsurprising, since it's about 4 in the morning. Heather considers the possibility that the neighbor is hearing impaired to a great degree.
3:43am - Michael goes upstairs to check out the changed sound level. From the deck on the 4th story, he yells that although the music is still clearly audible outside, it is "better" inside. Heather goes inside.
3:45am - Heather stuffs earplugs in both ears and tries not to hear the music.
4:01am - Heather decides that she really can still hear the music and is too worked up to sleep, so she goes downstairs to play Mass Effect.
4:12am - Michael joins Heather. Many discussions about the sanity/rudeness/evilness of the neighbor ensue. At some point, it is decided that Peter Gabriel is, in fact, the devil, due to the appearance of dancing dead chickens in the "Sledgehammer" video. Later, it is unclear why this conclusion seemed so inevitable, but the stigma remains. The neighbor comes to be known as "one of Peter Gabriel's minions." Many scathing letters to the neighbor are mentally composed. Revenge schemes are plotted and abandoned as unethical/illegal/immoral and just plain unChristian.
6:30am - The sun is starting to come up. Heather's headache has reached epic proportions and the music seems to have mellowed, so sleep is attempted again.
10:30am - Heather's parents call to confirm they're all going to "Oklahoma!" at the Fox Theatre.
10:51am - Heather attemps lucid conversation with her father. This was always going to go badly.
11:11am - Heather's mother calls back and sympathizes like an actual person.
11:42am - Showering happens. Heather successfully fails to drown.
Let me sum up the rest of the day here...all we got done was eating and picking up a FedEx package (which was a feat in itself, and turned out to be the wrong thing for the second time) before Heather's parents arrived for dinner and the show. We pick things up after we've gotten to bed at about 12:30...
Saturday night, 3:30am - Music. The volume is slightly less than last night, but still on the order of club bathroom. Heather goes to bang on the door again, not bothering to wake Michael.
3:40am - Heather is still banging. Volume is unchanged. Michael yells from the deck for her to come upstairs and he will hammer on the wall.
3:52am - Michael holds an IKEA table leg against the wall with a piece of cardboard in between. He hammers on the leg in interesting rhythmic patterns.
3:53am - Michael destroys the table leg. Fortunately, the table was only $12.
3:55am - The volume decreases to the point where earplugs block 50% of the songs. Actual sleep doesn't occur for probably another 45 minutes. Peter Gabriel is cursed.
The day unwinds in a headachy haze. We knock (nicely) on the neighbor's door about 7pm to try to talk to her. She does not answer. We compose a letter where Michael identifies many songs played during the nights and sorts the volumes she has produced at various times into two categories he calls, "LOUD" and "CRAZY LOUD". We slip it through her mail slot. A few attempts at cleaning are made.
This brings us to Sunday night.
10:30pm - Music starts.
11:30pm - We head to bed.
Monday,12:41am - As the music continues, Michael wields the table leg and hammer again.
12:47am - The volume decreases. Sleep is attempted.
12:53am - It's still too loud, even with the earplugs in. In lieu of weeping, Heather bangs on the table leg in an incessant fast staccato.
12:59am - Music decreases in volume to "earplug level".
Monday morning we slip another note in her door saying that things are better, but still very audible. We request a 10pm cutoff for that night, since Heather has a stupidly early meeting Tuesday morning and we are very sleep deprived.
Monday night, the music is slightly below earplug level. Prior to installation of earplugs, exhaustion takes over.
During the day Monday, Michael does some research. He discovers that Atlanta's sound ordinance specifies "nighttime hours" as 9:01pm-7am the next morning. The sound level should be less than 35dB at the shared wall. We consider purchasing a sound meter. We slip a note in her door thanking her for keeping the music below "earplug level".
Now, here is where it gets good. Tuesday, Michael calls our architect and finds out that she is a renter (hurray!) and tells him what's been happening. He's very apologetic and suggests we call "Fred" (not his real name), who was the financial partner for our duplex, and is therefore her landlord. Michael gets in touch with "Fred", who tells Michael that our neighbor text messaged him saying, "What's up with my neighbors...they keep banging on the wall and leaving me notes. Maybe this isn't the place for me." He suggests to Michael that if we find a tenant who will pay the $2K/month rent (that's more than our mortgage!!!), he can maybe have her evicted. LOL! Michael tells him that we just want to talk to her and "Fred" seems very relieved. "Fred" also drops the news that our neighbor runs a club in Cabbagetown. Michael does some research and finds that most clubs in Ctown close at 2:30am. Heather is somewhat relieved that the neighbor's occupation is actually legal, as "bartender" was the most legal and...kindest...option she could previously come up with.
You're thinking, "WHY DON'T YOU CALL THE POLICE!?!!??" But, you know, we may have to live with her for a while, and that's no way to start a relationship. Maybe banging on the wall isn't, either, but she didn't leave us with a whole lot of choices.
Last night was blissfully quiet. Heather's sure we're on a list somewhere as being "difficult".
Our neighbor plays her music really, Really, REALLY loud. She runs a club, so her eardrums are likely leathery thickend slabs of skin that can only be vibrated by a sheer force of nature. And Heather has no idea why she has descended to writing in third person.
Labels: lofty lives, rant-o-rama
The Chronicles of WALL-E: Speed Panda and the Iro...

redpajama_set_name: RedPajamaCommonCrawl


aardvark.dj: Halt! Who goes there!
There's a bit of me that will never grow up. The part that still giggles at fart noises and sniggers at childish innuendos. The part that still sticks my tongue out at people and tells 5 year olds jokes.
That part of me wants one of these room defenders. Die trespassing suckers!
Aren't you supposed to be studying my love!
World, meet my wife. She started an IT course today and is an extremely quick learner. She's clearly already grasped the concept of surfing the net when you're supposed to be working. Took me ages to learn that one properly.


Social networks make it easier than ever to identify, attract, engage and influence the decisions of your target market and ideal clients. Social media provides amazing and often free tools that make it possible for lawyers and other professional service providers to systemize and automate huge portions of their personal marketing and business development activities.
Far too often, I find that lawyers are not using social media and social networks to increase their books of business because they are simply to overwhelmed about exactly what to do and how to get started. I've developed a basic system to help lawyers get out of "social media overwhelm" and into upward action.
Social media makes it easy to convert what you've learned by "listening and learning" into compelling content that will attract your ideal clients and position you as a thought-leader in your industry. This happens when you are able to connect your solutions to your ideal client's exact needs. When you are ready to attract your ideal clients and position yourself as a leader, get started by fully optimizing your LinkedIn profile (www.LinkedIn.com) and Google profile (www.Google.com/profiles).
Use social networks to engage in online conversations that influence how your prospective clients, current clients and colleagues view your expertise and ultimately value your services. You can become more engaging by sharing information in a way that encourages your online community to let you know what they are thinking about things that matter to their businesses and lives. Questions, polls and surveys are a few ideas to help you get people talking. Your response to what your online community shares will influence how you are perceived and valued in your target market.
After you have worked through the process of listening, learning, attracting, positioning, engaging and working to influence your target market, it's time measure your impact and results. Here's how to do it … return to the goals that you set in step one of this framework and measure the results. Now, you have a record of your wins and losses.
After taking a look at your wins and loses, determine what changes need to be made to get better results. Make the necessary adjustments and start from the top.
Now that you know what to do, it's time for your Upward Action. Once you've gotten started, come back to this post and let me know your results. I'd love to hear how you are applying this content to growing your book of business.


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Mendendez Says Turkey Wants to Annex Turkish-Cypriot Side
By The National Herald
FILE - A Turkish military guard post with Turkey s flag, left, and Turkish Cypriot breakaway flag, right, is seen in front of the Famagusta, city, prior the Turkish President visit the Turkish occupied part of the island at the north, in Dherynia, Cyprus, Monday, July 19, 2021. (AP Photo/Petros Karadjias)
NICOSIA – United States Sen. Robert Menendez, a strong defender of Cyprus, said he believes Turkish President Recep Tayyip Erdogan plans at some point to annex the occupied northern third of Cyprus.
The New Jersey Democrat said it's because Erdogan has seen Russian President Vladimir Putin – whose country is a member of the United Nations Security Council – get away with doing it in Ukraine after invading.
"Erdogan sees the illegal annexation of part of Ukraine and takes note. Because he wants to do the same in northern Cyprus and annex the occupied territories," he said, said Middle East Eye.
In September, Erdogan said he would increase troop numbers on the occupied side where Turkey keeps 40,000 soldiers and said they would never be removed, which led to the collapse of the last round of reunification talks on July, 2017 at the Swiss resort of Crans-Montana.
Cypriot President Nicos Anastasiades, whose government is a member of the European Union that Turkey has fruitlessly been trying to join since 2005, earlier said he thinks Turkey wants to take over the island.
UN Envoy Said to Blame Greek-Cypriots for Inaction on Reunification
NICOSIA - Cypriot President Nicos Anastasiades has demanded the United Nation's Special Representative Colin Stewart to confirm or deny reports in a Turkish newspaper that the envoy blamed the Greek-Cypriots for failure to bring the island together.
Workers Stage 3-Hour Strike in Cyprus to Demand Pay Raises
Tenure Ending, Anastasiades Ducks 60 Minutes Cyprus Corruption Report


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Read Next RS Recommends: This $69 Security Camera Offers High-Tech Features Without the High Price
May 9, 2016 1:06PM ET
Watch Kesha Cover Lady Gaga's 'Til It Happens to You' at Humane Society Gala
"I want to dedicate this song to every man, woman, child and animal that has ever been abused," singer tells crowd
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Kesha appeared onstage at the Humane Society Gala in Los Angeles Saturday night to deliver an emotional, bare rendition of Lady Gaga's Oscar-nominated song "Til It Happens to You." "I want to dedicate this song to every man, woman, child and animal that has ever been abused," Kesha said before her performance.
Kesha is still involved in a legal battle against Lukasz "Dr. Luke" Gottwald, the producer she has accused of sexual and verbal abuse. "Til It Happens to You," written by Diane Warren, was penned for the campus rape documentary The Hunting Ground.
Kesha barely made it through the opening line – "Tell me it gets better" – before being overcome with emotion, forcing her to step back from the microphone. After quickly pulling herself back together, Kesha continued with the powerful piano ballad.
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In February, after Kesha's injunction against producer Dr. Luke was denied, Lady Gaga took to Instagram to defend the singer.
"The very reason women don't speak up for years is the fear that no one will believe them or their abuser has threatened their life or life of their loved ones/livelihood in order to keep their victim quiet and under control," Gaga wrote. "What happened to Kesha has happened to many female artists, including myself, and it will affect her for the rest of her life.
"No one needs to validate Kesha," she continued. "Why is victim always the 'liar'? Why do we let people in a position of power get away with behaving inhumanely? These guys hide behind the legal system and it's their litigious behavior that is precisely what they use to rape these girls. 'Give me what I want or else I will come after you' and they have all the money and the resources to do it."
Following Kesha's cover, Lady Gaga tweeted:
Killed it @KeshaRose. I could feel your pain. Girl these boys won't be in charge forever. The wisdom of women is rising. Let's get louder
In This Article: Kesha,	Lady Gaga


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White County High School may refer to:

White County High School (Cleveland, Georgia), United States
White County High School (Sparta, Tennessee), United States

redpajama_set_name: RedPajamaWikipedia


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Earlier this month, Beth Orton returned with her first album in six years, Sugaring Season. The folk/electronica sound is no longer the focal point - electronics only line one track on the album - and instead, the LP is a set of perfectly formed folk songs, rendered with deft musicality, the end result of the assembled group of session aces - including Marc Ribot on guitar, Sebastian Steinberg on bass and drummer Brian Blade - that make up Orton's band. Rather than sticking in one mode, however, Orton places a fleeting piano-led waltz ('See Through Blue') that barely reaches the two-minute mark in the centre of the LP, and closes proceedings with 'Mystery', where her finger-picked guitar and sweetly-toned vocals build on an underlying drone.
The sonic imprint of Nick Drake and John Martyn lingers in the airy vocal melodies and jazzy inflections of songs like 'Dawn Chorus' and 'Poison Tree', two artists who, after much deliberation, made it into Orton's Baker's Dozen. At numerous points during our conversation, Orton outlines, and re-outlines, her ethos for choosing them, explaining: "I just picked these records because I wanted to talk about records that have directly affected my writing, I suppose, and how I approach what I do." Was it easy cutting your choices down to 13? "It's horrible! No-one should be made to do it!"
Grinning and bearing it, Orton did make her choices, and in time for her upcoming UK tour, beginning on November 25 at The Assembly in Leamington Spa - click on her picture below to begin scrolling through the albums.


Super Eagles striker Victor Moses has revealed that it was injury that forced him out of the national team. Moses on loan at West Ham from Chelsea, was key to the Super Eagles winning the 2013 Africa Cup of Nations in South Africa with Coach Srephen Keshi in charge. But under coach Sunday Oliseh, Moses have yet to lace his boots for Nigeria.
Victor MosesHis last Super Eagles appearance was in the 2-0 loss to France at the 2014 World Cup but he has reaffirmed his commitment to Nigeria.
"I'm proud of being a Nigerian international and am always committed to playing for my country," Moses told BBC Sport.
"It's the best feeling representing your country and I always want to perform and give 100% for the team.
"There is a new manager and the team has been doing well but without me," said Moses, who misses his involvement.
"I'm prepared to give it my all and fight for a place on a regular basis, that's my aim.


Yesterday I posted the Parotta recipe and today of course it's going to be the side dish for that. You might have guessed it already; yeah it's the salna – the vegetarian Salna. The highlight of this recipe is that it's a zero oil recipe and I got this recipe from our chef friend Srini who in turn got it from a Street Side stall during his food exploration. It's the street side food or as we call it in Tamil Thalluvandi (தள்ளுவண்டி) style Salna. Usually the Thalluvandi style salna is thin in consistency.
Before getting into the recipe, I would like to thank Srini for sharing this wonderful recipe with me. For the vegetarian salna I didn't add any veggies (It's not vegetable salna ;-) ) but just went with Soya Chunks so as to mimic the meat version. But you can add veggies of your choice but don't overload the gravy with the veggies. You can also add cabbage stem while boiling the water to get more flavor. Discard the stem later. Usually we start these gravies with frying onions in oil. But this starts with boiling the water with dry masala ingredients. Interesting huh? When Srini shared the recipe I was amazed with the procedure and I know him very well and went ahead with the same procedure. Oh man.. It tasted super awesome.
Boil 3 cups of water in a heavy bottomed vessel.
Meanwhile grind coconut, shallots, garlic and saunf coarsely by adding ½ cup of water and set aside.
Soak the soya chunks in water.Chop the half of medium sized onion, tomatoes.
Once the water starts to boil add the cinnamon stick, peppers, bay leaf, cloves, and Elaichi.
Let it simmer for 5 to 7 minutes. Once the water changes its color add the chopped onions, tomatoes and slit green chillies.
Add the salt, turmeric powder and dagad phool powder.
Let it simmer for 20 minutes. Using a potato masher or ladle mash the ingredients nicely.
Now add red chilly powder,ground masala and the soya chunks and let it simmer for 15 more minutes.
If you feel the salna is very thin, mix 1 tbsp of besan with ½ cup of water and add it to the salna and simmer it for 5 minutes.
Garnish with cilantro and serve hot with Parotta.
A flavorful side for South Indian Style Parotta. This street side recipe doesn't use any oil but loaded with spices and with fresh ground masala.
Soak the soya chunks in water.
Chop the half of medium sized onion, tomatoes.
Add the red chilly powder, salt, turmeric powder and dagad phool powder.
Now add ground masala and the soya chunks and let it simmer for 15 more minutes.
You can add veggies like carrots, peas, potatoes instead of soya chunks.
Adjust water quantity according to you consistency preference.
Hi, tried this salna today and it was great!! We loved it!
Wow very different… Will try it out soon. And it's so god to have a chef friend. I envy you!! ?
What a flavorful and delicious looking Salna. Bookmarked to try sometime soon.
Vegetarian Salna looks wonderful and without oil a healthy recipe.
Zero oil, then this salna goes directly to my bookmarked dishes list.Thanks for sharing.
Thanks a lot priya. Let me know how it turned out.
Thanks GB. Glad you like it.
Love this flavorful, healthy and yummy recipe dear!


Prime Minister Scott Morrison has warned the nation to "brace itself for some difficult stories" as he revealed the terms of reference for the royal commission into quality and safety in the aged care sector.
The commission will hold its inquiries in Adelaide and will be headed by two commissioners, Mr Morrison told a media conference in Sydney. The inquiry will begin "as soon as practicable" with a final report to be handed down by April 30, 2020 and an interim report due next October.
Mr Morrison also pledged the government would "push ahead" with current reforms to the aged care system, including the establishment of an independent aged care quality and safety watchdog.
He said the royal commission's terms of reference were finalised after receiving input from more than 5,100 Australians.
It would be a "future-focused inquiry", he said. "This is very much looking at what has happened but it is also very much about understanding what needs to be done into the future," he told reporters.
"It is a very future-focused royal commission but it is going to learn from the mistakes and problems of the past.
"We need to establish a national culture of respect for senior Australians and Australians as they age.
Health minister Greg Hunt said the two royal commissioners, West Australian Supreme Court Justice Joseph McGrath and Lynelle Briggs, a former Public Service Commissioner and Medicare CEO, would bring a frank and fearless approach to their investigation.
He said the terms of reference were deliberately broad but dealt in particular with quality and safety, how best to deliver care services, how best to care for the increasing number of people with dementia, and the delivery of accessible, affordable and quality aged care.
It would also look at delivering care through innovative investment, enabling consumers choice and control and options for young people with disabilities in aged care.
The commissioners also have the power to examine any other matters they consider relevant to the inquiry.
Mr Morrison said the introduction of a single set of quality standards and the establishment of an Aged Care Quality and Safety Commission from next year had already been legislated for and would not be affected by the royal commission.
"We'll be pushing ahead with all of those," he said. "The royal commission is in addition to all of the things that we've already initiated, all of the additional funding that we're already providing, and we will be getting on with our job as a government to deliver quality aged care services all around the country.
He added that the commissioners would be able to consider the question of staffing ratios in tandem with general workforce issues.
"The general issues about the workforce and how it's engaged in the sector are covered in the terms of reference, and if the royal commission wants to address those issues they are able to through the terms of reference," he said.
Consumer advocate Ian Yates of COTA Australia said the terms of reference were broad enough to "pretty well talk about anything" while providing clear direction.
He welcomed the inclusion of the issues of choice, control, workplace references, medication, restraint, population diversity, the interface with primary care, acute care and disability as well as management and governance. He said COTA also welcomed the fact that previous reviews and recommendations would be considered, and that support would be made available witnesses who needed it.
"Certainly they will forensically look at what went wrong and why, and to what extent, but also they're being asked to look at best practice and innovation," he told Community Care Review.
LASA CEO Sean Rooney said the terms of reference reflected the views of LASA members that the royal commission needed to focus on making Australia's aged care system better. However he said the commission must also closely examine aged care funding and sustainability.
Scott Morrison, I like it "We need to establish a national culture of respect for senior Australians and Australians as they age" We really do!


"Arise, go to Nineveh, that great city, and proclaim to it the message that I tell you" (Jon 3:2). With these words the Lord spoke to Jonah and directed him to set out towards that great city, which was about to be destroyed for its many evils. In the Gospel, we also see Jesus setting out towards Galilee to preach the Good News (cf. Mk 1:14). Both readings reveal a God who turns his gaze towards cities past and present. The Lord sets out on a journey: to Nineveh, to Galilee, to Lima, to Trujillo and Puerto Maldonado… the Lord comes here. He sets out to enter into our individual, concrete histories. We celebrated this not long ago: he is Emmanuel, the God who wants to be with us always. Yes, here in Lima, or wherever you are living, in the routine of your daily life and work, in the education to hope that you impart to your children, amid your aspirations and anxieties; within the privacy of the home and the deafening noise of our streets. It is there, along the dusty paths of history, that the Lord comes to meet each of you.
Sometimes what happened to Jonah can happen to us. Our cities, with their daily situations of pain and injustice, can leave us tempted to flee, to hide, to run away. Jonah, and we, have plenty of excuses to do so. Looking at the city, we can start by saying that there are "citizens who find adequate means to develop their personal and family life – and that pleases us – yet the problem is the many "non-citizens", "the half-citizens" or "urban remnants". They are found along our roadsides, living on the fringes of our cities, and lacking the conditions needed for a dignified existence. It is painful to realize that among these "urban remnants" all too often we see the faces of children and adolescents. We look at the face of the future. Seeing these things in our cities and our neighbourhoods – which should be places of encounter, solidarity and joy – we end up with what we might call the Jonah syndrome: we lose heart and want to flee (cf. Jon 1:3). We become indifferent, and as a result, anonymous and deaf to others, cold and hard of heart. When this happens, we wound the soul of our people. As Benedict XVI pointed out, "the true measure of humanity is essentially determined in relationship to suffering and to the sufferer… A society unable to accept its suffering members and incapable of helping to share their suffering and to bear it inwardly through 'com-passion' is a cruel and inhuman society".
After they arrested John, Jesus set out to Galilee to proclaim the Gospel of God. Unlike Jonah, Jesus reacted to the distressing and unjust news of John's arrest by entering the city; he entered Galilee and from its small towns he began to sow the seeds of a great hope: that the Kingdom of God is at hand, that God is among us. The Gospel itself shows us the joy and the rippling effect that this brought about: it started with Simon and Andrew, then James and John (cf. Mk 1:14-20). It then passed through Saint Rose de Lima, Saint Turibius, Saint Martin de Porres, Saint Juan Macías, Saint Francisco Solano, down to us, proclaimed by that cloud of witnesses that have believed in him. It has come to us in order to act once more as a timely antidote to the globalization of indifference. In the face of that Love, one cannot remain indifferent.
Jesus invites his disciples to experience in the present a taste of eternity: the love of God and neighbour. He does this the only way he can, God's way, by awakening tenderness and love of mercy, by awakening compassion and opening their eyes to see reality as God does. He invites them to generate new bonds, new covenants rich in eternal life.
Jesus walks through the city with his disciples and begins to see, to hear, to notice those who have given up in the face of indifference, laid low by the grave sin of corruption. He begins to bring to light many situations that had killed the hope of his people and to awaken a new hope. He calls his disciples and invites them to set out with him. He calls them to walk through to the city, but at a different pace; he teaches them to notice what they had previously overlooked, and he points out new and pressing needs. Repent, he tells them. The Kingdom of Heaven means finding in Jesus a God who gets involved with the lives of his people. He gets involved and involves others not to be afraid to make of our history a history of salvation (cf. Mk 1:15, 21).
Jesus continues to walk on our streets. He knocks today, as he did yesterday, on our doors and hearts, in order to rekindle the flame of hope and the aspiration that breakdown can be overcome by fraternity, injustice defeated by solidarity, violence silenced by the weapons of peace.
Jesus continues to call us; he wants to anoint us with his Spirit so that we too can go out to anoint others with the oil capable of healing wounded hopes and renewing our way of seeing things. Jesus continues to walk and to awaken hope, a hope that frees us from empty associations and impersonal analyses. He encourages us to enter like leaven into where we are, where we live, into every corner of our daily life. The kingdom of heaven is among you, he tells us. It is there wherever we strive to show a little tenderness and compassion, wherever we are unafraid to create spaces for the blind to see, the paralyzed to walk, lepers to be cleansed and the deaf to hear (cf. Lk 7:22), so that all those we had given up for lost can enjoy the resurrection. God will never tire of setting out to meet his children. How will we enkindle hope if prophets are lacking? How will we face the future if unity is lacking? How will Jesus reach all those corners if daring and courageous witnesses are lacking?
Today the Lord calls each of you to walk with him in the city, in your city. He invites you to become his missionary disciple, so that you can become part of that great whisper that wants to keep echoing in the different corners of our lives: Rejoice, the Lord is with you!


Morris Pike, also known as Captain Book, is among severalcommunity members to be saluted at the Camp Pendleton ArmedServices YMCA's 65th Board Installation and Volunteer RecognitionDinner.
Pike will receive the program volunteer of the year award forhis support of the branch's Operation Hero after-school program andhis promotion of reading at schools on the base.
Pike makes appearances all over San Diego, dressing as thepirate Captain Book and giving away books through the KiwanisClub's Treasure Chest Literacy Program.
Also recognized at Thursday's dinner will be military volunteerof the year Staff Sgt. Luis Guzman, civilian volunteer of the yearLiz Rhea, and youth volunteer of the year John "Buddy" Hawthorne.John E. Ryan will be installed as the new board chairman.
Thinking young: Make way for the swinging principal. Rick Ausbygot a chance to rediscover his inner child when he spent a morningin kindergarten as part of Orange Glen Elementary School'sPrincipal for a Day program.
Principal Ausby switched with Jordan Kipp, who was the school'stop seller in the Parent Teacher's Association fundraiser. Jordangot to make announcements over the intercom, hand out perfectattendance awards to students and keep an eye on the lunchline.
He enjoyed the swinging so much, that he returned another dayfor 10 minutes more.
Ride 'em, Rotarians: Incoming district governors from all overthe world are coming to Escondido on Thursday for an evening of funand fellowship. About 80 of the future officers will enjoy aWestern dinner, bluegrass music from Too Much Fun and the chance toride a mechanical bull. That should make for some interestingphotographs and stories to take home. An Old West shootoutfeaturing "Sheriff" Frank Tecca, Gary Szytel as Black Bart and CarlSkaja as Judge Beam adds to the frivolity. The Rotary districtgovernors-elect are in San Diego for 10 days of required trainingbefore they take their posts.
Checkmate: Young chess players can test their tournament skillsbeginning Thursday when the Escondido Chess Club launches weeklycontests for kids. Youngsters from 4 to 17 have signed up for thetournaments, which will begin at 6 p.m. every Thursday at theEscondido Bridge Club, 2247 S. Centre City Parkway. The tourneywill continue for five to eight weeks, one game a week for eachplayer, until the top three positions are determined, said clubmember John Goddard. "We're not looking for super-strong players.Anyone who plays is welcome," he said. "Chess will improve theirthinking capacity." The entry fee is $20. Contact (760) 317-1744 orescondidochess.com.
Photo request: The Escondido Union School District is trying toput together a gallery of pictures of all the district's pastsuperintendents. Chris Haney, executive assistant to thesuperintendent, has been unable to come up with a photograph ofRalph B. Hawley, who served in the post from 1958-61. Haney hopes arelative, friend or former colleague might have a picture of Hawleyfrom that time that she can use. Call (760) 432-2110 or e-mailchaney@eusd4kids.org.


As I laid in my bed with the covers pulled closely to my face, my body exhausted, my mind frantic, my thoughts mixed with everything from the daily to-do's to intense emotions about life's purpose. I'm not sure why at 12:00am on a work night my mind started to go there, but it did, and I had to deal with it regardless of the late hour. Life lesson # 101: If you don't allow your mind the time to 'deal with stuff', it will make time with or without your permission, and it's usually unexpected…12:00am happened to be when it needed to voice it's concerns.
My prayer had no reply. I waited with hope in my heart. I focused on the rising and falling of my chest with each breath.
After an hour I finally fell asleep with no answer to my prayer.
Annoyed and under-slept, I bent down to put a running shoe on a tiny foot. As I knelt down with the shoe in my hand, little did I know that my prayer was seconds away from being answered. I placed the running shoe on the tiny foot and as I was lacing it up I heard Jesus say to me, "I washed the disciples feet." God knew exactly what I needed to hear and why. For months I had felt disrespected, looked down upon, dumb and undervalued, but in that moment I was reminded of my identity to serve. Jesus, having the greatest title in the whole Earth, 'the Son of God' bent down and washed His disciples feet. Feeling like I had a title but being placed in the least desired position I had carried feelings of disrespect for months. Jesus didn't have to announce his title to others in order to show that He was important and respected. He knew deep within His being that He is the Son of God. Yet, He was not too important to bend down and wash feet. Jesus is completely sure of who He is and never shies away from His identity. He lived a recklessly bold and humble life.
God's words to me, "I washed the disciples feet" echoed in my heart as a reminder of who I am and how I am to live.
I am His daughter and I am loved. I may have a title and the least desired position and feel like I spend most of my days tying shoes and zipping zippers, but if Jesus bent down to wash feet then who am I to say that tying shoes is above me. I am not what I do but the attitude in which I do what I do. I am not just 'a shoe-tyer', I am a servant. I have not come to be served but to serve.
Sounds like so many nights of my own… Thank you for sharing this, I can relate to every part of it.


text:
Humphrey Appleby
Sir Humphrey Appleby
GCB, KBE, MVO, MA (Oxon)
Nigel Hawthorne as Sir Humphrey Appleby
"Open Government"
"The Tangled Web"
Sir Nigel Hawthorne
Henry Goodman (2013 revival)
Permanent Secretary / Cabinet Secretary
Lady Appleby
Sir Humphrey Appleby, GCB, KBE, MVO, MA (Oxon), is a fictional character from the British television series Yes Minister and Yes Prime Minister. He was played originally by Sir Nigel Hawthorne, both on stage and in a television adaptation of the stage show by Henry Goodman in a new series of Yes, Prime Minister.[1] In Yes Minister, he is the Permanent Secretary for the Department of Administrative Affairs (a fictional department of the British government). In the last episode of Yes Minister, "Party Games", he becomes Cabinet Secretary, the most powerful position in the service and one he retains during Yes, Prime Minister. Hawthorne's portrayal won the BAFTA Award for Best Light Entertainment Performance four times: 1981, 1982, 1986 and 1987.
1 Fictional biography
1.1 Honours
4 Real-life references
Fictional biography[edit]
Sir Humphrey won a "classical scholarship" at Winchester College before reading Classics at Baillie College, University of Oxford (clearly based on Balliol College, Oxford: Humphrey is frequently seen wearing a Balliol College tie) where he got a First. After National Service in the Army Education Corps he entered the Civil Service. From 1950 to 1956 he was successively the Regional Contracts Officer, an assistant principal in the Scottish Office, on secondment from the War Office (where he was responsible for a serious mistake that was revealed in "The Skeleton in the Cupboard"). In 1964, he was brought into the newly formed Department of Administrative Affairs, where he worked until his appointment as Cabinet Secretary. He is recommended for a KBE award early on in the series in "The Official Visit". The Dean of Baillie describes him as "too clever by half" and "smug" (The Bishop's Gambit).
On Humphrey's possible private situation, Jonathan Lynn, one of the creators of Yes, Minister and Yes, Prime Minister, commented: "We always supposed that Sir Humphrey lived in Haslemere, had a son at Winchester and a daughter at Bedales and that his wife was a sensible woman who made cakes for church socials and enjoyed walking the family bulldog. I think that Humphrey's hobbies were reading (mainly biographies), listening to classical music, and occasionally visiting the RSC, the National Theatre or the Royal Opera House, where he was on the Board. His holidays were probably spent walking in the Lake District and, occasionally, sailing in Lymington. On the whole, he had a slightly warmer relationship with his dog than his family."[2]
According to the foreword (dated 1989), of the book The Complete Yes Minister: The Diaries of a Cabinet Minister by the Rt. Hon. James Hacker MP, a novelisation of the series, he spent his last days in St Dympna's Hospital for the Elderly Deranged, after the "advancing years, without in any way impairing his verbal fluency, disengaged the operation of his mind from the content of his speech." This contradicts the date of death given in Politico's Book of the Dead.[3]
Honours[edit]
Sir Humphrey has been appointed a Knight Grand Cross of the Order of the Bath (GCB), a Knight Commander of the Order of the British Empire (KBE) and a Member of the Royal Victorian Order (MVO).
Character[edit]
Sir Humphrey is a master of obfuscation and manipulation, often making long-winded statements to confuse and fatigue the listener. An example is the following monologue from the episode The Death List: "In view of the somewhat nebulous and inexplicit nature of your remit, and the arguably marginal and peripheral nature of your influence within the central deliberations and decisions within the political process, there could be a case for restructuring their action priorities in such a way as to eliminate your liquidation from their immediate agenda."[4] Addressing his Minister, he means to suggest by this that a terrorist group which had previously conspired to assassinate the Minister is no longer planning to do so, as they believe he is simply not important enough politically. Sir Humphrey is committed to maintaining the status quo for the country in general and for the Civil Service in particular, and will stop at nothing to do so—whether that means baffling his opponents with technical jargon, employing a dizzying array of stalling and delaying tactics, withholding information or concealing vital documents in mammoth piles of papers and reports, strategically appointing allies to supposedly impartial boards, or setting up an interdepartmental committee to immobilise his Minister's proposals with red tape, and occasionally outright lying. Throughout the series, he serves as Permanent Secretary at the Department of Administrative Affairs, with Jim Hacker as minister; he is appointed Cabinet Secretary shortly before Hacker's elevation to the role of Prime Minister.
Sir Humphrey represents, in many ways, the perfect technocrat. He is pompous, arrogant, elitist and regards his less-well-educated minister with some contempt. He frequently uses both his mastery of the English language and even his superb grasp of Latin and Greek grammar to perplex his political master and to obscure relevant issues under discussion. However, his habit of using language as a tool of confusion and obstruction is so deeply ingrained that he is sometimes unable to speak clearly and directly even when he honestly wishes to be clearly understood. He genuinely believes that the Civil Service knows what the average person needs and is the most qualified body to run the country, the joke being that not only is Sir Humphrey, as a high-ranking Oxford-educated Civil Servant, quite out of touch with the average person but also the Civil Service judges what is "best for Britain" to be that which in actuality is best for the Civil Service. Jim Hacker, on the other hand, tends to regard what is best for Britain as being whatever is best for his political party or his own chances of re-election. As a result, Sir Humphrey and Hacker often clash.
He still holds women to be the fairer sex and is thus overly courteous, frequently addressing them as "Dear lady". Like Hacker, Sir Humphrey enjoys the finer things in life, and is regularly seen drinking sherry and dining at fine establishments, often with his fellow civil servant Sir Arnold Robinson, who was Cabinet Secretary throughout Yes, Minister. Sir Humphrey is also on the board of governors of the National Theatre and attends many of the gala nights of the Royal Opera House. His interests also extend to cricket, art and theatre.
Humphrey is usually smooth, calm and collected within his element of bureaucracy and procedure, but has become so adept at working within and maintaining the system of government that, whenever anything unexpected is sprung on him, whether it be Hacker ordering him to negotiate with a rogue councillor, or honours in his department being made dependent on economies, Humphrey immediately crumbles, on a few occasions being reduced to stuttering out garbled platitudes such as "the beginning of the end" or "it cuts at the very roots", although he usually regains his composure pretty quickly to push things back on track.
In a Radio Times interview to promote the first series of Yes, Prime Minister, Nigel Hawthorne observed, "He's raving mad of course. Obsessive about his job. He'd do anything to keep control. In fact, he does go mad in one episode. Quite mad."[5]
In Yes Minister, Sir Humphrey maintains a civil and outwardly deferential but fundamentally adversarial relationship with his new minister, Jim Hacker. When keeping the Minister busy is not sufficient to prevent him from proposing new policy, Sir Humphrey is not above deceiving or even blackmailing him. He frequently manipulates Hacker by describing new proposals that he is opposed to as "very brave" or "extremely courageous", playing upon Hacker's fear as a politician of anything which may fly in the face of prevailing public opinion.[6]
He has a slightly more amicable relationship with his subordinate, the Minister's Principal Private Secretary, Bernard Woolley. He frequently lectures the naïve Woolley in the realities of political matters. When Woolley's loyalty to the Minister is inconvenient to Sir Humphrey's plans, he readily makes oblique threats about Woolley's job prospects should he defy Sir Humphrey. However, he is equally quick to defend Woolley from outsiders. His closest on-screen friendships are with Sir Arnold Robinson, Cabinet Secretary during Yes Minister; Sir Frederick "Jumbo" Stewart, Permanent Secretary of the Foreign and Commonwealth Office; and the banker Sir Desmond Glazebrook. He is married, although his wife plays virtually no role in either series and is only seen once: next to him in bed in the Series One episode "Big Brother".
Real-life references[edit]
Sir Humphrey has become a stereotype associated with civil servants, and the phrase "Bowler-hatted Sir Humphreys" is sometimes used when describing their image. Satirical and investigative magazine Private Eye often refers to Sir Humphrey with the definite article 'the' to indicate someone in the civil service the magazine considers of similar character, e.g. "[name] is the present Sir Humphrey at the Department for Rural Affairs". In the 1930s "Sir Horace", after Sir Horace Wilson, a senior official close to Prime Minister Neville Chamberlain, became a sobriquet for a civil servant with delusions of grandeur; this is thought to have influenced the choice of the name "Sir Humphrey".[7]
A spoof obituary for Sir Humphrey appears in Politico's Book of the Dead, written by his creators, Antony Jay and Jonathan Lynn, which includes some biographical details, including dates of birth and death, which he shares with Nigel Hawthorne, the actor who portrayed him.
Sir Humphrey was voted the 45th greatest comedy character in Channel 4's 2007 "The World's Greatest Comedy Characters" poll. He was also voted 31st in a poll of "100 Greatest TV Characters", also on Channel 4.[8] Upon Nigel Hawthorne's death, the following appeared on the Editorial page of The Ottawa Citizen under the heading "No, Minister":
"It is sadly that we report on Sir Nigel Hawthorne, elsewhere referred to as Sir Humphrey Appleby. While it would be premature to commit ourselves to a definitive position on his merits or even his existence, a committee is being struck to consider the possibility of a decision, in the fullness of time, to regret his passing, if any."
The character was resurrected for the 2010 general election campaign in a series of short sketches on BBC Two's late evening current affairs programme Newsnight. The sketches were written by Jay and Lynn, and Sir Humphrey was played by Henry Goodman.
Henry Goodman also played the part of Sir Humphrey in the 2010 stage production of Yes, Prime Minister.[9]
Humphrey, a cat employed as the Chief Mouser to the Cabinet Office at 10 Downing Street from 1989 to 1997, was named after Sir Humphrey.[10]
^ "Yes, Prime Minister - Production Details". Retrieved 4 February 2013.
^ Lynn, Jonathan. "Yes Minister Questions & Answers". Jonathan Lynn official website. Archived from the original on 19 November 2014.
^ Dale, Iain, ed. (2003). The Politico's Book of the Dead. London: Politico's.
^ "Speaking to be understood". Local Government Improvement and Development. Archived from the original on 30 April 2012.
^ Radio Times: 4–10 January 1986
^ "Sir Humphrey Appleby and the tale of the prescription charge". The Daily Telegraph. 19 March 2009. Retrieved 6 November 2015. "That's very brave of you, minister. An extremely courageous decision," he'd say. At this Jim Hacker's political antennae would get the message that what he had in mind was political suicide and the 'brave' plan - whatever it was - would be quickly dropped.
^ Thorpe, D.R. (1996). Alec Douglas-Home. London: Sinclair-Stevenson. p. 69. ISBN 9781856192774.
^ "The One Hundred Greatest TV Characters". Channel 4. Archived from the original on 30 October 2010.
^ "Chicester Minister Bound for Gielgud, 17 Sep". Whats On Stage. 11 June 2010. Archived from the original on 13 October 2012. Retrieved 12 June 2010.
^ White, Michael (21 March 2006). "Michael White: Humphrey, cat; born 1988, died 2006". the Guardian. Retrieved 3 March 2018.
Yes Minister / Yes, Prime Minister
Jim Hacker
Bernard Woolley
Annie Hacker
Sir Arnold Robinson
Dorothy Wainwright
Sir Frank Gordon
The Official Visit
The Economy Drive
The Right to Know
The Compassionate Society
Doing the Honours
The Death List
The Greasy Pole
The Quality of Life
A Question of Loyalty
The Skeleton in the Cupboard
The Moral Dimension
The Bed of Nails
The Whisky Priest
The Middle-Class Rip-Off
Yes, Prime Minister
The Ministerial Broadcast
The Smoke Screen
A Real Partnership
A Victory for Democracy
The Bishop's Gambit
A Diplomatic Incident
A Conflict of Interest
The Patron of the Arts
The National Education Service
The Tangled Web
List of fictional places in Yes Minister
Politician's syllogism
Ji Mantriji
Retrieved from "https://en.wikipedia.org/w/index.php?title=Humphrey_Appleby&oldid=903978565"
Yes Minister characters
Fictional civil servants
Fictional characters introduced in 1980
Fictional knights
Fictional University of Oxford people


Upcycling old books to create new favorites as blank book journals or diaries. A rare Dr. Seuss classic titled Happy Birthday to You, ideal for a scrapbook or guestbook, with tons of blank writing paper and cardstock (scrapbook quality, acid free). This oversized book journal measures about 10 x 8 inches.


text:
Home > Vol. 12, No. 11, Nov 2020 >	Ishisaka
Relationship Between Blood Pressure Levels on Admission and the Onset of Acute Pneumonia in Elderly Patients With Cerebral Hemorrhage
Taishi Ishisaka, Yuta Igarashi, Kumie Kodera, Tazuo Okuno, Takuro Morita, Taroh Himeno, Kazu Hamada, Hiroshi Yano, Toshihiro Higashikawa, Osamu Iritani, Kunimitsu Iwai, Shigeto Morimoto, Masashi Okuro
Background: We have reported that hypertension on admission in elderly patients with acute cerebral infarction is an independent predictor for the development of acute pneumonia. However, the relationship between blood pressure on admission owing to cerebral hemorrhage and the development of pneumonia has not been fully investigated. In this study, we evaluated the relationship between blood pressure levels on admission and the development of pneumonia in elderly patients with cerebral hemorrhage who were in the acute phase.
Methods: Subjects consisted of 117 elderly patients with cerebral hemorrhage who were in the acute phase and were emergently admitted to the Department of Geriatric Medicine, Kanazawa Medical University between 2005 and 2015 (59 males and 58 females, the mean age ± standard deviation (SD) of 80 ± 8 years, and the range of 65 - 98 years). Blood pressure levels on admission were classified into the following four groups: normal blood pressure/mild hypertension group (systolic blood pressure of < 160 mm Hg and diastolic blood pressure of < 100 mm Hg), moderate hypertension group (systolic hypertension of 160 - 179 mm Hg or diastolic blood pressure of 100 - 109 mm Hg), severe hypertension group (systolic hypertension of 180 - 199 mm Hg or diastolic blood pressure of 110 - 119 mmHg), and serious hypertension group (systolic blood pressure of ? 200 mm Hg or diastolic blood pressure of ? 120 mm Hg). Between the two groups (group of patients with acute pneumonia and group of those with absence of pneumonia), age, sex, body mass index (BMI), history of stroke, history of heart disease, chronic kidney disease, diabetes, dyslipidemia, prehypertension, blood pressure on admission, Japan Coma Scale (JCS) on admission, white blood cell count, C-reactive protein (CRP), albumin, bleeding sites, bleeding amount, and the presence or absence of centerline shift on brain computed tomography (CT) images were retrospectively evaluated. Furthermore, factors related to cerebral hemorrhage in the development of acute pneumonia in patients with cerebral hemorrhage were verified.
Results: Of the 117 patients, 30 (25.6%) had acute pneumonia. Age, sex, bleeding amount, midline shift, blood pressure classification on admission, JCS, white blood cell count, CRP, albumin, diabetes were adopted as confounding factors in the development of acute pneumonia. Results of multiple logistic regression analysis showed significant differences between these two groups in the following four items: CRP, white blood cell count, JCS, and blood pressure classification on admission. After adjustment of these confounding factors, the incidence of acute pneumonia in the blood pressure groups other than serious hypertension group was set as 1, and the odds ratio of pneumonia onset in serious hypertension group was revealed to be 5.54, with the 95% confidence interval of 1.49 - 20.6.
Conclusions: We found that serious hypertension on admission is a risk factor for the development of acute pneumonia in elderly patients with cerebral hemorrhage who are in the acute phase.
Elderly; Cerebral hemorrhage; Blood pressure on admission; Acute pneumonia


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Courts are waking up to the cost of climate change
The Trump administration's push for fossil fuel extraction has faced some notable setbacks in the courts.
Natasha Geiling Twitter Oct 4, 2017, 8:00 am
(CREDIT: AP Photo/Mead Gruver)
When considering the costs and benefits of a fossil fuel project — from building a single pipeline to expanding some of the biggest coal mines in the country — how much consideration should be given to the project's eventual contribution to climate change-causing carbon emissions?
That's a question that has plagued regulators, environmental groups, and courts for years. But this summer, in the span of a month, four different decisions came to the same conclusion: when deciding whether or not to allow a fossil fuel project to move forward, you have to take into consideration how the project will impact carbon emissions — even if those emissions would be released far from the boundaries of the project in question.
"At the high level, this wave of court decisions is an indicator that courts are pushing for accountability, and a true accounting of climate and public health costs of these projects," Mary Anne Hitt, director of the Sierra Club's Beyond Coal Campaign, told ThinkProgress. "That is going to be a big challenge to Trump's anti-climate science and pro-polluter agenda."
Court rules Trump administration can't just suspend EPA's methane rule
Trump's anti-environment agenda just suffered a blow.
The wave of decisions began in mid-August, when a U.S. District Judge blocked a proposed expansion of an underground coal mine in Montana, arguing that the Office of Surface Mining (OSM) failed to properly consider how the proposed expansion would impact climate change. Environmental groups argued — and the court agreed — that OSM focused primarily on alleged economic benefits of the expansion, like local taxes, while refusing to use any metric to analyze the harm that the expansion would cause.
The OSM, in effect, put its "thumb on the scale by inflating the benefits of the action while minimizing its impacts," the court ruled.
Weeks later, the D.C. Circuit Court vacated permits for an entirely different fossil fuel project on similar grounds. It found that the Federal Energy Regulatory Commission (FERC) had failed to adequately consider how construction of the Sable Trail pipeline — which would run from Alabama to Florida — would result in more greenhouse gas emissions from the burning of natural gas. As a result, the court ruled that FERC, which has been notably loathe to consider the climate impacts of various projects, had to redo its assessment.
It was a win for pipeline opponents who have long argued that FERC acts as little more than a rubber stamp for fossil fuel projects. A recent investigation from the Center for Public Integrity lends credence to those claims, finding that the regulatory body has only rejected two pipeline proposals in the last 30 years.
Then, in a surprising twist, the Tenth Circuit Court of Appeals, a conservative-leaning court, ruled in mid-September that the Bureau of Land Management (BLM) had improperly calculated the climate impacts of expanding several federal coal leases in Wyoming's Powder River Basin, forcing the agency redo its environmental impact study. The court found that BLM's assertion that there was essentially no difference between approving the expansion of the leases — which include two mines that produce about 20 percent of the country's coal used for electricity generation — and rejecting the leases; if the expansion were rejected, BLM reasoned, the same amount of coal would simply be mined elsewhere.
Environmental groups argued that BLM's analysis was a willful misreading of the economics of the energy market, because if the expansions were not granted and less coal was extracted from those mines, utilities would turn to cheaper, and less carbon-intensive options, like natural gas or renewables.
"If you take a significant amount of a commodity on the market, you are probably going to change the price of that commodity," Nathaniel Shoaff, a senior attorney with the Sierra Club and one of the attorneys that argued the case before the 10th Circuit, told ThinkProgress. "That's not surprising. If the price of milk suddenly goes up, people are going to buy less milk."
Three days later, a state board in Washington overturned two key permits that had been issued for a massive methanol project along the state's Columbia River, finding that the project's environmental impact study had not properly considered its greenhouse gas emissions. And like they had done following the three previous decisions, environmentalists cheered the finding, calling it a win for advocates who have long argued that agencies needed to take a broader approach to their consideration of climate impacts.
The Trump administration is ramping up its war on clean water
There is a serious, concerted effort going on to undermine clean water.
"You can't build a massive fossil fuel project like this and pretend that the impacts end at the property line," said Nathan Matthews, staff attorney for the Sierra Club, told Oregon Public Broadcasting.
As individual cases, each decision represents a notable — albeit, small — barrier for each of these fossil fuel projects. The National Environmental Policy Act (NEPA), a cornerstone of environmental law that requires agencies to analyze the environmental impacts of major projects, is a notoriously broad statute. Under NEPA, agencies simply have to conduct an honest accounting of the costs and benefits of a particular project; they are not necessarily required to pick the most cost-effective outcome. As a result, any of the projects in question ostensibly could still move forward once agencies redo their environmental assessments to more fully account for the costs of climate change impacts.
But environmental experts and attorneys who worked on the cases see the decisions, when taken together, as a sign of something potentially much larger than individual projects — they see the realization, at least in the judicial branch, that the costs of climate change can no longer be ignored by federal agencies.
"In some unexpected places, you're seeing the courts say 'these projects just can't go forward unless there is honest accounting of public,'" Sierra Club's Hitt said. "It seems like a striking development that courts are pushing for true accounting and accountability, and it seems like it's going to loom larger and larger to what Trump is trying to accomplish."
One place these court rulings could have particular influence is in the Trump administration's freeze of the Department of the Interior's review of the federal coal leasing program, which the Obama administration created to make sure that the program included a full accounting of the financial and environmental costs to taxpayers. Part of the Trump administration's argument for freezing the review was ostensibly that an overarching review was not needed because individual leases are required to undergo environmental studies under NEPA — an argument that Sierra Club attorney Shoaff says is seriously undermined by the recent court decisions, especially the two concerning coal lease expansions.
Trump's environmental assault met with immediate legal challenges
Environmental groups are ready to take Trump to court.
According to Shoaff, the assumption that expanding a coal mine would have no impact on greenhouse gas emissions because coal would simply be mined elsewhere is "appears in every single federal coal lease" that he has seen. And since two courts recently ruled that such an assumption is based on a faulty understanding of energy markets and economics, that could spell legal trouble for federal coal leases moving forward.
"We just invalidated the assumption that is baked into every single federal coal leasing environmental impact statement," Shoaff said. "So if the government wants to point to the climate impact it does, it's going to be pointing to faulty analysis every single time."
The legal requirement that agencies conduct a full accounting of the costs — and benefits — of a particular proposal could also undermine the administration's attempt to roll back the Clean Water Rule, an Obama-era rule that tried to define the legal scope of the Clean Water Act. In arguing for the rule's repeal, the EPA's economic analysis failed to consider the benefits of leaving the rule in place — things like the increased protection for wetlands, which could generate between $306 and $501 million annually. Environmental groups have already expressed their intent to challenge the rule-making process once the repeal is made final.
Generally, Shoaff says, the recent spate of court decisions shows that the judicial branch isn't willing to separate economic realities from agency's decisions about climate and the environment.
"Agencies aren't going to be allowed to just disown the climate impacts of what they are doing by claiming that it's not going to have any influence on the marketplace," he said. "They are no longer just going to be able to dodge this question. At some point, the agency is going to have to answer this."
#Climate, #Courts, #Fossil Fuels, #Trump Administration