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Artisan State Photo Book Review
323 reviews of Van Leeuwen Artisan Ice Cream "Every great city has a great ice cream shop. In the case of NYC, we have countless. However, Van Leeuwen is.
A selection of iconic 18th and 19th Century images from The John Derian Picture Book come to life through a collection of beautiful silk scarves. Shop All.
For green friends, send eco friendly gifts straight from nature. A simple, but hearty Bonsai plant or stalks of bamboo shoots certainly has an earthy feel.
The 19th annual book festival packs. mainstreetartsfest.org. Photo ops abound along 40 miles of beautiful wildflowers on a route that is officially open April 1-30. The three-day festival.
Several magazine and book accounts state that it sold over 1 million. Jim Geraghty in the National Review said in 2015 that the book showed "a much softer,
Computer Technology Free Images The computer-generated hologram produces complex. as those used to make liquid crystal displays — to create dynamic images. The researchers are now working to optimize the technology by reducing. May 31, 2019 · Pompeo urged close ally Britain this month not to use Huawei's technology to build new 5G networks because of concerns it could be a vehicle for Chinese spying. Free democracies have a duty. Technology has made life simpler, at the same time, it has made it complicated! Ever had to send a video, photo, or any type of file between your smartphone and computer for free? If you are an impatient person, you probably hate the 'processes' involved. This royalty-free photo is about white laptop computer, library, quiet, education, school, university, technology, online
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During his coaching career where he amassed 249 victories, Holtz was the head coach of William & Mary, North Carolina State, Arkansas. Enjoying all the regular features of the Fiesta such as.
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It includes one night in a superior room, full Irish breakfast, a 25 min spa treatment each and afternoon tea for two overlooking the state's woodlands or visit. With a choice of tea or gourmet.
Quick Homemade Artisan Bread is the faster way to make homemade bread! You will love this recipe because it only uses 4 ingredients and cooks in just 30 minutes. Impress at your next dinner when you serve this tasty homemade bread.
The Chimú culture was centered on Chimor with the capital city of Chan Chan, a large adobe city in the Moche Valley of present-day Trujillo, Peru.The culture arose about 900 AD, succeeding the Moche culture, and was later conquered by the Inca emperor Topa Inca Yupanqui around 1470, fifty years before the arrival of the Spanish in the region. The Chimú resided on a strip of desert on the.
Mar 4, 2019. Read the full Wine Country Gift Baskets review. Some state laws regulate the shipment of alcoholic beverages to consumers. Gift Tree offers an Artisan Cheese of the Month Club where you can sign up for several months of gourmet cheese baskets or, Best photo books 2019: picture the possibilities.
The young adults also will sell products they make at the theater's artisan. (Photo: Amy Coady) In the fact-inspired six-actor production, a gentle children's book with an apparent hidden message.
276 reviews of Mountain State Brewing Co. "Good pizza and beer right by the mountain at Wisp! Came here with a group of 12 and they were able to accommodate us. We all split a few pizzas and everyone seemed to really enjoy them! I got the fire…
She is also the type of woman whom generations of Irish women were told, by both church and State, they could never be. making her own slides from slivers of ivory. Her book Sketches with the.
Photographers Around The World Etymology. The word "photography" was created from the Greek roots φωτός (phōtos), genitive of φῶς (phōs), "light" and γραφή (graphé) "representation by means of lines" or "drawing", together meaning "drawing with light".Several people may have coined the same new term from these roots independently. Experience the nineteenth century through photographs that document world events or. Photography: The World Through the Lens delivers around 2 million. Fifth Annual Street Shooting Around the World Exhibition – 2019. In 2000 he was the founder of the iN-PUBLiC street photographers group which played a. "I like [photography] because I want to help my. shelter and support to Yemeni families and people in crisis around the. Professional and amateur photographers around the world are invited to submit their best panoramic
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We have seen quite a lot this year. After curating and sharing 2,239 links with 264,016 designers around the world, we have isolated a few trends in what our industry is writing, talking, and thinking about.
And, in what looks like something ripped from the pages of Kipling's Jungle Book, a vibrant, green-on-green botanical. and he often gifts pearls of wisdom as you're rocked and wooed into a state of.
Shop new, used, rare, and out-of-print books. Powell's is an independent bookstore based in Portland, Oregon. Browse staff picks, author features, and more.
Situated just off I-26, the Country Inn & Suites ® by Radisson, Columbia Airport, SC lies five minutes from Columbia Metropolitan Airport (CAE) and offers complimentary airport shuttle service. In town to see the Gamecocks play or take a college tour? The University of South.
After lunch at the Imperial, they headed out to review the military. the most skilled artisan of the fabric of a happier Ireland. Certainly, he was the most picturesque figure in the struggle; and.
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Photo by Drew. largest ice maze (Guinness Book of World Records). Instigator behind Emerald Beach at the Erie Basin Marina. Co-created Flurrious! winter festival. Co-creator of Rusty Chain Beer.
Book now at Wallsé in New York, NY. Explore menu, see photos and read 1460 reviews: "Good food, service and wine and pleasantly quiet place"
Osama Bin Laden Dead Photo Real Websites For Photographers Free Or, like Highsmith's photos, you can download it for free from the Library of Congress, with no restrictions. The choice is yours. 3:28 p.m., July 30: This post has been updated to explain that all. saying that the "worst of the worst" are selected in the cost-free process. Last month, when the winners for Fiscal Year 2020. Professional photography and artist websites using HTML5 mobile ready templates and optional Flash designs. Online hosting and tools to promote and sell your work. FolioLink.com powers the. PicturesPro.com is the developer of Sytist made for photographers to sell their photos, booking calendar, online contracts, green screen proofing and more. This website has a listing of several tutorials that will help you learn digital photography
Book clubs, fans: enhance your experience of The Storyteller – try baking Minka's. AARP.com (February 27, 2013 blog review ). I brought artisan loaves to her doctors. we were encouraged to state our opinions, no matter how controversial. The picture book was of Cinderella, but she must have been thinking of.
Seiko Epson Corporation (セイコーエプソン株式会社, Seikō Epuson Kabushiki-gaisha) (Epson being an abbreviation for "Son of Electronic Printer"), or simply Epson, is a Japanese electronics company and one of the world's largest manufacturers of computer printers, and information and imaging related equipment. Headquartered in Suwa, Nagano, Japan, the company has numerous.
Photo / AP Vajiralongkorn. At the same moment, the artisan also began to engrave the Royal Seal of State. During the whole period, monks were chanting auspicious prayer, Brahmins were blowing conch.
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Mar 28, 2018. According to her publisher Grand Central, the book will also reveal details about the rise of her career since her debut as a 17-year-old actress.
The same artisan had created both essentially at the same time," Askeland wrote in a paper recently published in the journal New Testament Studies. King objected to this conclusion in her Biblical.
73 reviews of Barr Mansion & Artisan Ballroom "We got married at Barr Mansion and it was perfect, despite the torrential rain the day before that closed down the airport. Yes that really happened. I know. What the F. HOWEVER- the day was still…
U.S. Secretary of Education Betsy DeVos petted a lizard, read a Dr. Seuss book, heard tiny violins. While the tour was under way, the Nebraska State Education Association sent out a photo of its.
The plaque is now in the Louvre in Paris, France (image by Bob Hall via Wikimedia Commons) Many of the ancient graphic narratives that survive today were funded by the state. in the Book of Daniel.
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Now, we come to the new 2018 food world definition of mindfulness, which I will describe as simply "the quality or state of being conscious or aware. Movies, documentaries and books have shifted.
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At the time, the field of wine criticism was gaining momentum—the magazine's circulation that year surpassed a hundred thousand—and written tasting notes were moving beyond encyclopedic reference.
DRIVING DIRECTIONS AND MAPS ALONG I-75 DETROIT TO FLORIDA. Review by Barb & Ron Kroll. Along Interstate 75 (Mile Oak Publishing) ISBN 9781896819389. Are you planning a drive to Florida along Interstate 75?
I used to have to go into Paris to get a good artisan loaf of bread, fine French cheeses. Even more ambitiously, 2016 saw the genesis of the Métropole du Grand Paris, a huge, state-sponsored effort.
State St., near the triangular convergence of State. (I also ate my way through dozens of corned beef and other sandwiches, plus bowls of chicken soup. See the photo gallery above.) Related: For.
A variety of house-made sauces include the curry dressing served atop "Steph's Chicken," (sprinkled with Golden (State) raisins. at the bar and a curated collection of books and music for sale.
Dec 24, 2018 · 50 state road trip: One roadside attraction in every state. From giant teapots and tires to candy factories and time capsules, you'll find a detour-worthy stop wherever your road trip takes you.
One of my most reader-tested and approved recipes! This crusty, fluffy artisan bread needs only 4 ingredients and 5 minutes to come together… you won't believe how easy and delicious it is! I have something amazing to share with you today! I mean, you've seen artisan bread before but you've.
Osama Bin Laden Dead Photo Real
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I had the total pleasure of singing with Michael for a forthcoming edition of the new BBC 1 show, Tonight's the Night. We sang the Grammy award winning, self penned, Tell me how am I supposed to live without you. Michael was extraordinary, very encouraging, supportive and a true gentleman in every sense of the word. It was a complete pleasure & dream come true to sing with an artist and gentleman whom I respect musically, personally & professionally. Thank you for this once in a life time opportunity Michael & the BBC. Look forward to your concert tour in November, here in the UK. Love the new album.....outstandingly good!
thanks to share your amazing experience with Michael! welcome!
Many, many congratulations to you Carol on singing with Michael.
This TV program starts on the UK BB1 next saturday and I am really looking forward to seeing your episode with Michael.
I too have met Michael on several ocasions and know what a wonderful person he really is and how comfortable and relaxed he would have made you feel. He realy is a wonderful human being isnt he?
Huge welcome to the board Carol.
Thank you so much for posting and replying to MB's post on his blog. What an amazing experience for you! Thank you for sharing with us here!


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Maj. Gen. Anthony Jackson: Reader Rebuttal: 241…
Maj. Gen. Anthony Jackson: Reader Rebuttal: 241 Toll Road
Official seal of the Marines.
By Orange County Register
March 24, 2010 at 6:35 a.m.
Marine Corps Installations West and Marine Corps Base Camp Pendleton would like to present the Marine Corps' perspective on the 241 Toll Road project and the Transportation Corridor Agencies attempt to extend the 241 from its current terminus in Rancho Santa Margarita to where the toll road would eventually connect with Interstate 5 on Camp Pendleton.
It is very important first to understand the mission of Marine Corps Base Camp Pendleton. Camp Pendleton provides high-quality ranges, training areas and facilities to the operating forces so our Marines and sailors can prepare to execute any required mission.
The history of Orange County and TCA efforts to extend the 241 goes back about 30 years, when, in 1981, Orange County officials adopted a proposed alignment of the entire 241 by putting the toll road on the County's Master Plan of Arterial Highways.
Camp Pendleton first became aware of Orange County's vision of building a toll road through base property in 1984. The Marine Corps initially opposed the Orange County proposal, and later, TCA proposal. However, the Marine Corps did offer the possibility of accommodation in mid-1988 when the commandant of the Marine Corps stated that on-base routing might be possible, but only if the toll road could be located on an area of the base that did not negatively impact Camp Pendleton's training mission. The only viable option in the view of the Marine Corps would be to route it somewhere within San Onofre State Park's 1,300-acre lease of base property east of I-5. The Marine Corps' position has been consistent throughout our involvement with this proposed toll-road project.
Ultimately, however, this proposed state-park alignment was denied by the California Coastal Commission, which then led the TCA to propose a new toll road route through a vital training area on Camp Pendleton. The newest TCA toll road plan suggests that it be located outside the state park lease area of Camp Pendleton by pushing the alignment further into the base. While the new alignment may be acceptable from the state park's perspective, it is not acceptable to Camp Pendleton or the Marine Corps as it does not meet the Marine Corps' long-maintained stipulation that this proposed project not negatively impact the base mission. The TCA's new proposed route does, in fact, create negative impacts, which explains the reason behind the secretary of the Navy's recent letter to Sen. Dianne Feinstein, expressing the Department of the Navy's nonsupport of the new alignment.
In our view, it's time for the TCA to find another alternative to it's current proposed alignment of the 241 Toll Road through vital training areas on Camp Pendleton.
Letters to the Editor: E-mail to letters@ocregister.com. Please provide your name and telephone number (telephone numbers will not be published). Letters of about 200 words will be given preference. Letters will be edited for length, grammar and clarity.
Newsom's bungled vaccine rollout misleads seniors
Here's to hoping Joe Biden remembers his 'you can't eat equality' line
A big data system for public education?
The future of conservatism isn't Trumpism, it's liberty

redpajama_set_name: RedPajamaCommonCrawl


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from numpy.testing import Tester
test = Tester().test

redpajama_set_name: RedPajamaGithub


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Next Up WWE's Naomi Reveals How She Plans To Prove To Critics She Can 'Go In A Different Direction' In Wrestling
April 10, 2021 10:02AM EDT
Kanye West's Ex Amber Rose Rubs Shoulders With His Nemesis Drake At LA Party – Pics
Beth Shilliday
Senior Evening Writer
Amber Rose partied with Drake as stars gathered at The Nice Guy for a first big night out amid L.A's COVID club restrictions being relaxed.
Just like old times! The Nice Guy in West Hollywood was hoppin' on a Thursday night again for the first time in over a year. With COVID restrictions finally eased, the Apr. 8 evening saw Kanye West's former girlfriend Amber Rose, 37, partying shoulder to shoulder with Ye's nemesis Drake, 34, in a star filled night that also saw the Jenner sisters, Chris Brown and Justin Bieber and wife Hailey Baldwin hit the club to finally have an A-list mix and mingle.
Amber was in attendance with her music executive boyfriend Alexander "AE" Edwards, 32, who is also the father of her 18-month-old son Slash Electric. She arrived looked all dressed up for the private party in a heavy faux fur knee-grazing Dalmatian style coat that was white with black flecks throughout it. She paired it with simple black leggings that ended just below her knees and rocked stylish open toe strappy heels and black sunglasses to complete her look.
Amber Rose at The Nice Guy in West Hollywood on Apr. 8, 2021. (BACKGRID)
Drake at The Nice Guy in West Hollywood on Apr. 8, 2021. (BACKGRID)
It's unclear if Amber and Drizzy interacted inside the party. The "God's Plan" singer was seen outside The Nice Guy still holding his drink in his hand, while looking stylish in a black long sleeved sweater and leather pants. Drake wore several chic chains around his neck, and is still wearing his hair with the shape of a small heart shaved in at the left side of his forehead.
Amber and Kanye dated from 2008-2010, and she was spotted out with Drake just a few months after she and Kanye split. Drizzy also felt empowered that he could be a better artist than the 808's and Heartbreak rapper. "When I was a kid trying to figure out what I liked, it was Ye who I related to the most," he told The Source in 2011.
"He was an artist, in every sense, from his cover art to his music. Now, I would say, he is really great [pause] competitor…and friend, at the same time…My goal is to surpass everything he's accomplished. I don't want to be as good as Kanye, I want to be better," Drizzy proclaimed. In 2018 there were rumors that it was Kanye who told Pusha T about Drake having a secret son, which Pusha told the world about on his track "The Story Of Adidon." Ye later denied leaking that information to Pusha, but he and Drake never remained on good terms. Drake is now completely open about his love for his three-year-old son Adonis.
Kendall Jenner and boyfriend Devin Booker are seen leaving the Nice Guy in West Hollywood. on Apr. 8, 2021. Photo credit: Mega
It wasn't just Drake and Amber who rolled up to The Nice Guy on Apr. 8. It was a star-studded party that saw Kendall Jenner bring her boyfriend, Phoenix Suns star Devin Booker to the bash. It was also a couple's date night for Justin and wife Hailey, who rocked a sexy black corset top.
There was also an ex-encounter, as Kylie Jenner and her former flame Tyga also hit up The Nice Guy separately. While the 23-year-old cosmetics mogul was photographed leaving the nightclub, the rapper remained inside with his new girlfriend Camaryn Swanson. Ahh the celebrity drama that is now back on again thanks to L.A. County moving into a new COVID tier where indoor bars and restaurants were able to start operating at 50 percent capacity or 200 patrons as of Apr. 5. The near-misses and awkward run in's are already on!
Amber Rose	Drake	Kanye West
Kylie Jenner Has Awkward Run-In With Ex-Boyfriend Tyga During Night Out With Kendall
Hailey Baldwin Stuns In Super Sexy Plunging Corset During Romantic Night Out With Justin Bieber
Drake's Son Adonis, 3, Shows Off His Basketball Skills In Adorable Video


The ongoing challenge for commercial off-the-shelf (COTS) system developers is to balance the competing approaches to reduce the system's size, weight, power, and cost (SWaP-C) while trying to deploy the most modern technologies. Today, system integrators are confronting a rapidly narrowing margin for achieving that balancing act. While the power and density of devices has increased, platform ambient boundary conditions haven't changed. The result is tighter and tighter margins. The only option: Become more efficient in removing heat from the system.


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Delhi: Government of Delhi has sent proposal to Lg to hold mayoral elections before 26
Manish Sisodia, Deputy CM
Photo: ANNI
The Delhi government has become active in swearing the newly elected councilors of MCD and conducting the election of the mayor, deputy mayor and six members to be elected from the house. The Delhi government has sent a proposal to the Lieutenant Governor to hold the meeting of MCD House on 18, 20, 21 or 24 January for the oath to the councilors and for the mayoral election.
Deputy Chief Minister Manish Sisodia tweeted on Thursday about the proposal sent to the Lieutenant Governor. He said that the MCD had asked for the House meeting to be held on January 30, but the Delhi government has sent a proposal to convene the House meeting before January 26. He said the MCD has been operating without a mayor for the past eight months. For this reason, it is not right to postpone the election of the mayor.
Last Monday, the MCD had sent a report to the Lieutenant Governor about the failure to take the oath of office to the council members in the House on January 6 and the failure to elect the mayor, deputy mayor and members of the standing committee. Apart from this, the MCD had also urged him to set a date for convening the Assembly of the House. The MCD, for its part, had proposed to hold a meeting on 30 January. At the same time, the MCD had blamed members of the Aam Aadmi party for the uproar in the House.
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hindi news for today
Delhi: Case Registered Against Arshdeep Employees Under UAPA, Terrorists In 14 Day Pretrial Detention By Police – Delhi Case Registered Against Arshdeep Employees Under Uapa
Mayor of Delhi: The ruling party may have to bear the brunt of the delay in the mayoral elections
Delhi News: New emergency department for women and children started in GTB


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Natural history of nasal vestibulitis associated with paclitaxel, docetaxel, and other chemotherapy agents: a Minnesota Cancer Clinical Trials Network (MNCCTN) study
Elizabeth J. Cathcart-Rake, David Zahrieh, Deanne Smith, Susan Young, Shaylene McCue, Amanda O'Connor, Stephan Thomé, Mario Lacouture, Terra Register, Jill Piens, Bret B. Friday, Charles L. Loprinzi
Quantitative Health Sciences
Purpose: To describe the natural history of nasal vestibulitis in patients receiving taxane chemotherapy, including incidence, severity, and associated symptoms. Methods: Eligible patients with minimal or no baseline nasal symptoms were enrolled in this natural history study at initiation of a new chemotherapy regimen. Patients completed nasal symptom logs each time they received a chemotherapy dose. This manuscript reports upon the patients who received paclitaxel, docetaxel, or non-taxane non-bevacizumab chemotherapy. The proportions of patients within each cohort reporting any treatment-emergent nasal symptoms were estimated, with corresponding exact 95% confidence intervals. A cumulative incidence function was estimated within the chemotherapy cohorts to calculate the cumulative incidence rate of treatment-emergent nasal vestibulitis, treating death and disease progression as competing risks. Results: Of the 81 evaluable patients, nasal symptoms were reported by 76.5% (58.8%, 89.3%) receiving paclitaxel, 54.2% (32.8%, 74.5%) receiving docetaxel, and 47.8% (26.8%, 69.4%) receiving non-taxane and non-bevacizumab chemotherapy. Of the three pairwise chemotherapy group comparisons, both the tests comparing the cumulative incidence function between the paclitaxel and non-taxane non-bevacizumab chemotherapy cohorts and between the paclitaxel and docetaxel cohorts achieved statistical significance at the 5% level with a higher incidence of treatment-emergent nasal vestibulitis in the paclitaxel cohort in both comparisons (P = 0.026 and P = 0.035, respectively). These significant differences were retained in the cumulative incidence function regression analysis controlling for age, smoking history, allergies, and asthma. Most patients in the paclitaxel cohort reported nasal symptoms as moderate or severe (56%). Conclusion: Patients receiving paclitaxel chemotherapy experience a high incidence of nasal symptoms.
Supportive Care in Cancer
Nasal vestibulitis
Dive into the research topics of 'Natural history of nasal vestibulitis associated with paclitaxel, docetaxel, and other chemotherapy agents: a Minnesota Cancer Clinical Trials Network (MNCCTN) study'. Together they form a unique fingerprint.
Docetaxel Medicine & Life Sciences 100%
Paclitaxel Medicine & Life Sciences 90%
Natural History Medicine & Life Sciences 90%
Nose Medicine & Life Sciences 72%
Drug Therapy Medicine & Life Sciences 52%
Incidence Medicine & Life Sciences 33%
Cathcart-Rake, E. J., Zahrieh, D., Smith, D., Young, S., McCue, S., O'Connor, A., Thomé, S., Lacouture, M., Register, T., Piens, J., Friday, B. B., & Loprinzi, C. L. (2021). Natural history of nasal vestibulitis associated with paclitaxel, docetaxel, and other chemotherapy agents: a Minnesota Cancer Clinical Trials Network (MNCCTN) study. Supportive Care in Cancer, 29(11), 6253-6258. https://doi.org/10.1007/s00520-021-06190-0
Natural history of nasal vestibulitis associated with paclitaxel, docetaxel, and other chemotherapy agents : a Minnesota Cancer Clinical Trials Network (MNCCTN) study. / Cathcart-Rake, Elizabeth J.; Zahrieh, David; Smith, Deanne; Young, Susan; McCue, Shaylene; O'Connor, Amanda; Thomé, Stephan; Lacouture, Mario; Register, Terra; Piens, Jill; Friday, Bret B.; Loprinzi, Charles L.
In: Supportive Care in Cancer, Vol. 29, No. 11, 11.2021, p. 6253-6258.
Cathcart-Rake, EJ, Zahrieh, D, Smith, D, Young, S, McCue, S, O'Connor, A, Thomé, S, Lacouture, M, Register, T, Piens, J, Friday, BB & Loprinzi, CL 2021, 'Natural history of nasal vestibulitis associated with paclitaxel, docetaxel, and other chemotherapy agents: a Minnesota Cancer Clinical Trials Network (MNCCTN) study', Supportive Care in Cancer, vol. 29, no. 11, pp. 6253-6258. https://doi.org/10.1007/s00520-021-06190-0
Cathcart-Rake EJ, Zahrieh D, Smith D, Young S, McCue S, O'Connor A et al. Natural history of nasal vestibulitis associated with paclitaxel, docetaxel, and other chemotherapy agents: a Minnesota Cancer Clinical Trials Network (MNCCTN) study. Supportive Care in Cancer. 2021 Nov;29(11):6253-6258. https://doi.org/10.1007/s00520-021-06190-0
Cathcart-Rake, Elizabeth J. ; Zahrieh, David ; Smith, Deanne ; Young, Susan ; McCue, Shaylene ; O'Connor, Amanda ; Thomé, Stephan ; Lacouture, Mario ; Register, Terra ; Piens, Jill ; Friday, Bret B. ; Loprinzi, Charles L. / Natural history of nasal vestibulitis associated with paclitaxel, docetaxel, and other chemotherapy agents : a Minnesota Cancer Clinical Trials Network (MNCCTN) study. In: Supportive Care in Cancer. 2021 ; Vol. 29, No. 11. pp. 6253-6258.
@article{afe772463eb74a46b7d6fe69cdbeb08d,
title = "Natural history of nasal vestibulitis associated with paclitaxel, docetaxel, and other chemotherapy agents: a Minnesota Cancer Clinical Trials Network (MNCCTN) study",
abstract = "Purpose: To describe the natural history of nasal vestibulitis in patients receiving taxane chemotherapy, including incidence, severity, and associated symptoms. Methods: Eligible patients with minimal or no baseline nasal symptoms were enrolled in this natural history study at initiation of a new chemotherapy regimen. Patients completed nasal symptom logs each time they received a chemotherapy dose. This manuscript reports upon the patients who received paclitaxel, docetaxel, or non-taxane non-bevacizumab chemotherapy. The proportions of patients within each cohort reporting any treatment-emergent nasal symptoms were estimated, with corresponding exact 95% confidence intervals. A cumulative incidence function was estimated within the chemotherapy cohorts to calculate the cumulative incidence rate of treatment-emergent nasal vestibulitis, treating death and disease progression as competing risks. Results: Of the 81 evaluable patients, nasal symptoms were reported by 76.5% (58.8%, 89.3%) receiving paclitaxel, 54.2% (32.8%, 74.5%) receiving docetaxel, and 47.8% (26.8%, 69.4%) receiving non-taxane and non-bevacizumab chemotherapy. Of the three pairwise chemotherapy group comparisons, both the tests comparing the cumulative incidence function between the paclitaxel and non-taxane non-bevacizumab chemotherapy cohorts and between the paclitaxel and docetaxel cohorts achieved statistical significance at the 5% level with a higher incidence of treatment-emergent nasal vestibulitis in the paclitaxel cohort in both comparisons (P = 0.026 and P = 0.035, respectively). These significant differences were retained in the cumulative incidence function regression analysis controlling for age, smoking history, allergies, and asthma. Most patients in the paclitaxel cohort reported nasal symptoms as moderate or severe (56%). Conclusion: Patients receiving paclitaxel chemotherapy experience a high incidence of nasal symptoms.",
keywords = "Chemotherapy side effects, Nasal vestibulitis, Paclitaxel, Symptom management",
author = "Cathcart-Rake, {Elizabeth J.} and David Zahrieh and Deanne Smith and Susan Young and Shaylene McCue and Amanda O{\textquoteright}Connor and Stephan Thom{\'e} and Mario Lacouture and Terra Register and Jill Piens and Friday, {Bret B.} and Loprinzi, {Charles L.}",
note = "Funding Information: This work was supported by the Breast Cancer Research Foundation and by the Gateway for Cancer Research. Mario Lacouture is supported in part through the NIH/NCI Cancer Center Support Grant P30 CA008748. Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",
journal = "Supportive Care in Cancer",
T1 - Natural history of nasal vestibulitis associated with paclitaxel, docetaxel, and other chemotherapy agents
T2 - a Minnesota Cancer Clinical Trials Network (MNCCTN) study
AU - Cathcart-Rake, Elizabeth J.
AU - Zahrieh, David
AU - Smith, Deanne
AU - Young, Susan
AU - McCue, Shaylene
AU - O'Connor, Amanda
AU - Thomé, Stephan
AU - Lacouture, Mario
AU - Register, Terra
AU - Piens, Jill
AU - Friday, Bret B.
AU - Loprinzi, Charles L.
N1 - Funding Information: This work was supported by the Breast Cancer Research Foundation and by the Gateway for Cancer Research. Mario Lacouture is supported in part through the NIH/NCI Cancer Center Support Grant P30 CA008748. Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
N2 - Purpose: To describe the natural history of nasal vestibulitis in patients receiving taxane chemotherapy, including incidence, severity, and associated symptoms. Methods: Eligible patients with minimal or no baseline nasal symptoms were enrolled in this natural history study at initiation of a new chemotherapy regimen. Patients completed nasal symptom logs each time they received a chemotherapy dose. This manuscript reports upon the patients who received paclitaxel, docetaxel, or non-taxane non-bevacizumab chemotherapy. The proportions of patients within each cohort reporting any treatment-emergent nasal symptoms were estimated, with corresponding exact 95% confidence intervals. A cumulative incidence function was estimated within the chemotherapy cohorts to calculate the cumulative incidence rate of treatment-emergent nasal vestibulitis, treating death and disease progression as competing risks. Results: Of the 81 evaluable patients, nasal symptoms were reported by 76.5% (58.8%, 89.3%) receiving paclitaxel, 54.2% (32.8%, 74.5%) receiving docetaxel, and 47.8% (26.8%, 69.4%) receiving non-taxane and non-bevacizumab chemotherapy. Of the three pairwise chemotherapy group comparisons, both the tests comparing the cumulative incidence function between the paclitaxel and non-taxane non-bevacizumab chemotherapy cohorts and between the paclitaxel and docetaxel cohorts achieved statistical significance at the 5% level with a higher incidence of treatment-emergent nasal vestibulitis in the paclitaxel cohort in both comparisons (P = 0.026 and P = 0.035, respectively). These significant differences were retained in the cumulative incidence function regression analysis controlling for age, smoking history, allergies, and asthma. Most patients in the paclitaxel cohort reported nasal symptoms as moderate or severe (56%). Conclusion: Patients receiving paclitaxel chemotherapy experience a high incidence of nasal symptoms.
AB - Purpose: To describe the natural history of nasal vestibulitis in patients receiving taxane chemotherapy, including incidence, severity, and associated symptoms. Methods: Eligible patients with minimal or no baseline nasal symptoms were enrolled in this natural history study at initiation of a new chemotherapy regimen. Patients completed nasal symptom logs each time they received a chemotherapy dose. This manuscript reports upon the patients who received paclitaxel, docetaxel, or non-taxane non-bevacizumab chemotherapy. The proportions of patients within each cohort reporting any treatment-emergent nasal symptoms were estimated, with corresponding exact 95% confidence intervals. A cumulative incidence function was estimated within the chemotherapy cohorts to calculate the cumulative incidence rate of treatment-emergent nasal vestibulitis, treating death and disease progression as competing risks. Results: Of the 81 evaluable patients, nasal symptoms were reported by 76.5% (58.8%, 89.3%) receiving paclitaxel, 54.2% (32.8%, 74.5%) receiving docetaxel, and 47.8% (26.8%, 69.4%) receiving non-taxane and non-bevacizumab chemotherapy. Of the three pairwise chemotherapy group comparisons, both the tests comparing the cumulative incidence function between the paclitaxel and non-taxane non-bevacizumab chemotherapy cohorts and between the paclitaxel and docetaxel cohorts achieved statistical significance at the 5% level with a higher incidence of treatment-emergent nasal vestibulitis in the paclitaxel cohort in both comparisons (P = 0.026 and P = 0.035, respectively). These significant differences were retained in the cumulative incidence function regression analysis controlling for age, smoking history, allergies, and asthma. Most patients in the paclitaxel cohort reported nasal symptoms as moderate or severe (56%). Conclusion: Patients receiving paclitaxel chemotherapy experience a high incidence of nasal symptoms.
KW - Chemotherapy side effects
KW - Nasal vestibulitis
KW - Paclitaxel
KW - Symptom management
JO - Supportive Care in Cancer
JF - Supportive Care in Cancer


These are Plat+ players' starting items for Nunu & Willump.
These are players' starting items for Nunu & Willump.
These are Plat+ players' few first purchases for Nunu & Willump.
These are players' few first purchases for Nunu & Willump.
These are the items Plat+ players buy for Nunu & Willump.
These are the full item builds players buy for Nunu & Willump.
These are the items that we find most often in Plat+ players' final inventories for Nunu & Willump. The %'s are number of occurences in final inventories divided by total games with the champion.
These are how Plat+ players' upgrade their skills for Nunu & Willump.
These are how players' upgrade their skills for Nunu & Willump.
These are the summoner spells used by Plat+ players' for Nunu & Willump.
These are the summoner spells used by players' for Nunu & Willump.
These are the runes chosen by Plat+ players' for Nunu & Willump.
These are the runes chosen by players' for Nunu & Willump.
This section helps highlight champions that Nunu & Willump usually wins against and champions that counter Nunu & Willump.
This section helps highlight champions that Nunu & Willump works well with.
Here's what we could find in recent patch notes for Nunu & Willump.
Here's what we could find in recent patch notes for items used often by Nunu & Willump.


I'm looking at the area of North Carolina that the hurricane is crossing: it is all flat, swampy, with lots of lakes. It won't weaken the storm much.
Storm's appearance is actually improving on IR and WV following landfall. Morehead radar is still showing a badly disrupted eye, and the land interaction won't help it, but there are signs it is trying to fill in the southern and eastern circulation.
Condition report: Winds about 10-15mph here near Annapolis, MD. Still a long way from the storm, the eye being around 270 miles south of me. The closest rain line should start hitting me in the next ten minutes or so.


Kolhapur is one of the cities, which are worth to be visited in Maharashtra. There are number of forts in this old city. Descended from its historic events, the city has many historical monuments and sites. During the periods of Satavahana kings and the Shilahar As, the magnificent temples of Kolhapur were constructed.
Kolhapur has number of tourist sites. The architecture of New Palace offers the visitors a combination of Jain and Hindu influences from Gujarat and Rajasthan, and local Rajwada style.
Chhatrapati Sahu Museum in the palace is also worth to visit. Rankala Lake, Old Palace, Town Hall Museum and Mahalaxmi are other sites, which are worth to visit. One can also organize excursions to Panhala, Vishalgad, Bhudargad, Paargad, Narasimha Wadi, Giroli Tourist Park, Dajipur Bison Sanctuary and Amboli, which are not so far from Kolhapur.
As far as shopping in Kolhapur is concerned, the city can be called as shoppers' delight. The city is famous for its Kolhapuri saaj, Kolhapuri chappals and Kolhapuri sarees. Har and malas, mohanmal, bormal, chaplahar, kolhapuri saaj, pohehar and putlihar are the jewelleries, which can attract that tourists' eye.
Kolhapur is popular for its cotton textiles, in particular Kolhapuri sarees. This city is also popular for its jewellery and leather sandals or Kolhapuri chappals. Here chappals of good quality are available as cheap as five pairs of sandals for less than Rs 500.
Distance between Kolhapur to Pune. The aerial distance from Kolhapur to Pune is 209 km while the road distance between Kolhapur to Pune is 235 km and it takes around 5 hours by car to reach.


for the Boston Red Sox in the opener of a three-game series against the Toronto Blue Jays on Tuesday at Fenway Park.But don't get excited — Sale will just be working as what is now called Nick Castellanos Jersey , "the opener," pitching the first two innings before departing."Two the first time, hopefully three the second time, then keep going," Rays manager Alex Cora said. "And then the last one, whenever it is, like a full-go, six or seven innings and 100 pitches."Article continues below …Nathan Eovaldi, who has been struggling, will get the long work behind Sale, whose bid for a first Cy Young Award appears to be have been erased by the lack of work.Rookie left-hander Ryan Borucki works for the Jays, who come in after a win Sunday in Cleveland and are playing out the string — using young players amid talk that manager John Gibbons will not return in 2019.Mookie Betts is 5-for-5 with three triples and a double against Borucki. Eduardo Nunez is 3-for-5 (.600), and J.D. Martinez and Brock Holt both 2-for-6 (.333). One of Martinez's hits was a home run.The current Red Sox roster is a cumulative 17-for-41 (.415) against Borucki.Sale is 12-4 with a 1.97 ERA. He has thrown 28 straight scoreless innings and had 10-plus strikeouts in seven of his last eight starts http://www.tigersfanproshop.com/authentic-james-mccann-jersey , averaging 15.88 Ks per nine innings during that span.He hasn't pitched since Aug. 12, when he returned to the DL after making one return start because of left shoulder inflammation.He has thrown five innings since July 27.The injury is not thought to be serious, but combined with Sale's history of being ineffective late in seasons — including a poor start in last year's American League Division Series, it is a concern.The Red Sox, who have won 98 games (49 home, 49 road) — salvaged the finale of a three-game series with the Houston Astros, winning Sunday night's game in what could be a postseason preview (a rematch of 2017?). The win lowered Boston's magic number to clinch a playoff spot to one and to win the AL East to 12."That was awesome," said Boston pitcher Rick Porcello, who started and couldn't take advantage of a 5-1 lead to get a no-decision. "Good ballclub over there, especially avoiding the sweep, especially the way we did it. It's a good win for us; we needed it."The Red Sox have gone 12-4 against the Blue Jays this season, including 6-1 at Fenway.The last time he faced the Blue Jays was May 11, when Sale struck out 15 in a nine-inning no-decision. He is 5-4 with a 2.83 ERA lifetime against Toronto.Borucki faces the Red Sox for the third time this season and the results have not been good. He has worked eight innings Shane Greene Jersey , yielding 17 hits and 11 runs (eight earned).Borucki had quality starts in eight of his 13 times on the mound since his recall in late June.The Jays (65-78) have split their last 10 games and gone 10-9 in their last 19.Toronto's Randal Grichuk avoided a concussion when he collided with a security guard's chair Sunday in Toronto. He is day to day after tests came back negative."They took him in to get X-rays and the concussion thing," Blue Jays manager John Gibbons said after the game. "He was conscious. I don't think he blacked out, to be honest with you. "I don't know that, but I saw him in the clubhouse between innings, and he was grinning and laughing a little bit, so that's a good sign."Said Gibbons: "He's a pretty boy, man. You don't want to hurt that face." OAKLAND, Calif. — The Seattle Mariners will hope veteran right-hander Mike Leake continues his fine pitching against the Oakland Athletics when the two American League wild-card hopefuls meet for a second consecutive day on Friday night.The third-place Mariners (75-59) gained a game on the A's (80-55) in the series opener when Wade LeBlanc rode a five-run first inning to a 7-1 victory that inched Seattle within 4 1/2 games in the battle for second place both in the AL West and AL wild-card race.The A's not only lost a game to the Mariners but failed to gain ground in their pursuit of first place in the West and the top spot in the wild-card race after Houston (82-52) and the New York Yankees (84-50) had lost earlier in the evening.Article continues below …Oakland will take the field Friday still 2 1/2 games behind the Astros and 4 1/2 back of the Yankees.Both the A's and Mariners took the field for the series opener coming off losses, with the Mariners having dropped three in a row, including two straight at San Diego, while the A's were only a little more than 24 hours removed from an emotional walk-off loss at Houston.A's manager Bob Melvin noted after Thursday's loss that Wednesday's defeat in Houston — in fact, the entire three games against the Astros during which Oakland suffered two close setbacks — played a role in the club's opener of a nine-game homestand."That last series took a lot out of us," Melvin said. "That's no excuse Sparky Anderson Jersey , but I saw a little (fatigue) today. Just one of those tough nights."Leake (8-8, 4.03 ERA) has faced the A's three times this season, with the Mariners winning all three, 7-4, 3-2 and 2-0. He did not get a decision in any of the wins despite allowing a total of just five runs and 15 hits in 20 2/3 innings.The 30-year-old has a 1-1 record and 2.50 ERA in six career starts against the A's.Leake has been especially tough this season on A's All-Star Jed Lowrie, holding him hitless in nine at-bats with two strikeouts.Oakland will pitch a veteran right-hander of its own, Mike Fiers (10-6, 3.15), who will be looking to remain unbeaten for the A's in a fifth consecutive start since being acquired from Detroit.Fiers pitched Oakland to a 3-2 win at Seattle earlier this month, allowing two runs and six hits in six innings.It raised the 33-year-old's lifetime record in seven starts against the Mariners to 2-1 with a 5.66 ERA, marks that include a 7-2 loss in May as a member of the Tigers.Jean Segura and Ben Gamel both homered off Fiers in that game.Segura was scratched from Thursday's starting lineup because of a bruised left shin suffered when he fouled a pitch off his leg Wednesday in San Diego. He is expected to return sometime during the remainder of the series.Robinson Cano has been tough on Fiers in the past, going 5-for-14 (.357) with a double and two home runs.


The Micke Grove Zoo Education Department is offering a variety of programs for toddlers, young children, children with special needs, and families. Our most popular family programs include: Zoo After Dark, Zoo Tots, and Toys-For-Critters! Click here to see and sign up for our available programs and activities.
When you visit the zoo, you can often expect to see our informative Education Station carts set up throughout the zoo. Here, families can learn about some of our animals in a more hands-on way, including informative talks from our docents, handling bio facts and models, and viewing informative graphics. We are currently featuring stations with information on primates, big cats, Madagascar and raptors.


The Pests That Love Falling Leaves "Leaves" is a very moving drama about three sisters. Muriel and her two sisters had dreams of becoming the new musical sensation just like, "The Supremes" – but fate intervene. Muriel fell in love and.
Small honey ants are native to the United States from the Canadian border to Nebraska, south to Texas and Florida and in New Mexico, California, Oregon, and Washington. Reproduction Small honey ant colonies usually have one active queen.
How do I get rid of the ants its winter and they are still all over the house. We have had exterminators but they won't go away. Submitted: 9 years ago.. They are the little black ants. What she has done in the past to get rid of them would curl your hair. She has sprayed, stomped, poisoned.
Remember, Argentine ants are small, so you need to look closely. Remove bridges:. A older beekeeper told me to put walnut leaves under the telescoping cover to get rid of ants. I have put that info into use this year in all of my hives.. Honey Bee Suite is dedicated to honey bees.
What is a Beg Bug? | Bed Bug Pest Identification, Facts, Advice Top 7 ant species you many encounter in U.S. The Ant Has More Than Just High Hopes But, we are nothing more than the ants we perceive as insignificant.. No More Important than Ants .. We have the choice and the capacity inside of us to show the whole world what we are made of or to just sit back and watch it all.Tiny tan worms in my bathroom When Are Silverfish Most Active? Where Your Pests Are Hiding In Your Home As a bonus, essential oils are environmentally friendly and safe for your family and pets. If you know where pests are coming in, or have a suspicion – such as crevices, cracks, windows and other.Silverfish also commonly eat glue and wallpaper paste. Finding damage to your wallpaper is a common trait of a silverfish infestation. They are also known to digest linens and cotton, which make the closets in your home and the clothes contained inside them wonderful targets for a silverfish infestation.Tiny, tiny bugs in bathroom – psciod mites? (phone, drains, bathtub) User Name: Remember Me: Password Please register to participate in our discussions with 2 million other members – it's free and quick! Some forums can only be seen by registered members.. worms? multilegged.Since most species of ants are dormant during the winter, you probably won't have to deal with a pest problem (or even know you have an infestation) all season. You may see a few foragers, but you're not likely to encounter many ants in the winter.If You Find a Bedbug at Home. Chances are, you have located the bed bug in or near your bed. By performing a few initial steps, you will make it easier for a comprehensive inspection.
Ultimately, the best way to get rid of an ant problem is to call a profession pest technician.. Ants tend to remain relatively dormant in winter and in colder conditions.. Ants feed on sugar, syrup, honey, fruit juice, fats, and meat.. They may leave for short periods only to return later when a new food source is located and.
Try to remove as much of the compacted compost as you can from the top of the urn and replace it with some loam-based John Innes No 3 mixed with a little multipurpose. use a greenhouse in winter.
CHARLOTTE, N.C. — After a brief but freezing cold winter, you probably aren't complaining. Ladybugs are easy to get rid of when you locate their entry. Ants aren't that easy. They only need 1/64.
55 thoughts on " Where do ants go in the winter? " Roberta Post author March 27, 2016 at 3:47 pm. I'm afraid I have no idea. You might want to check with some.
As they do this, they excrete a sticky substance that attracts sooty black mold and even ants. which will get rid of eggs. Repeat every two to three days for two weeks, and then as needed. These.


Welcome to Park Avenue Tattoo. Keeping it comfortable and classy.
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Trump Administration approves proposal to expand visitor access to the Wave
Expanded access to world-famous geologic feature in the Paria Canyon–Vermilion Cliffs Wilderness
ST. GEORGE, Utah – The Bureau of Land Management (BLM) today announced it has approved a proposal to expand visitor access to the world-famous geologic feature known as the Wave, located in the Paria Canyon–Vermilion Cliffs Wilderness on the Arizona Strip. Under the new decision, the number of hiking permits issued for the Wave will increase from 20 to 64 people and/or 16 groups per day, whichever comes first. The BLM could implement further increases or decreases in the future based on monitoring of resources and social conditions.
"The stunning beauty of the Wave is part of every American's public lands heritage, and we're honored to protect and manage it for generations to come," said Deputy Secretary Kate MacGregor. "This effort provides for additional safety for visitors, access to our nation's veterans, and ensures that in times like the COVID-19 pandemic, the American people have expanded access to recreational opportunities on their public lands."
"The Wave is one of the world's most incredible and visually stunning natural wonders," said Principal Deputy Assistant Secretary of the Interior for Land and Minerals Management Casey Hammond. "We're pleased to be able to expand options for public viewing of this amazing landscape in a way that's consistent with its preservation."
"We conducted robust environmental analysis and worked in collaboration with partners and interested stakeholders in an effort to allow more visitors access to the Wave, while maintaining wilderness character," said BLM Arizona State Director Ray Suazo. "I appreciate the close collaboration with Coconino County in Arizona and Kane and Washington Counties in Utah in managing this important natural area."
"We look forward to continuing our partnership with the Arizona Strip District on all aspects of the Paria Canyon–Vermilion Cliffs Wilderness and Wave management. The Kanab Field Office will continue to run the next day lottery in an efficient and respectful manner," said BLM Utah State Director Greg Sheehan. "This decision provides additional safety for visitors and will hopefully decrease the workload on Kane County's already-busy search and rescue personnel."
"The Kane County Sheriff's Office has been working closely with our federal partners at the Bureau of Land Management to improve the safety of visitors at the Wave. As visitation and interest has dramatically increased, the permit process has become more complex. We appreciate the leadership shown by the BLM on this safety issue. Improving the safety and overall experience of visitors here is clearly a shared priority. As the Kane County Sheriff, I feel very fortunate to have such a positive cooperative relationship with the Bureau of Land Management. We share a sincere love of public lands and a responsibility to those that visit. A big thank you from my office to folks at the BLM for recognizing this issue and working to solve difficult problems," said Kane County Sheriff Tracy Glover.
"Coconino County supports this decision to increase visitor access to the Wave in a manner that will preserve and protect the natural and scenic wonders of this landscape," said Coconino County Supervisor Lena Fowler. "We are excited about the opportunities for economic growth in our local communities that comes with this increase in recreational tourism."
"The Wave has become one of the most iconic and recognizable destinations in the world. Increased visitation and associated tourism is a vital part of the Kane County economy. The desire to visit The Wave has created some complex management concerns. These concerns have required a great deal of coordination between Kane County, the DOI and local BLM managers. Kane County sincerely appreciates the efforts put forth by key DOI and BLM officials who took interest in this issue and worked hard for a rapid resolution. Because of these efforts, visitors will be safer and have a better overall experience as they enjoy the beauty of public lands in our area," said Kane County Commissioner Andy Gant.
The decision supports Secretary's Order 3347, Conservation Stewardship and Outdoor Recreation, and Secretary's Order 3366, Increasing Recreational Opportunities on Lands and Waters Managed by the U.S. Department of the Interior. It strikes an appropriate balance by responding to the public's increased interest in visiting the site while minimizing environmental impacts and maintaining wilderness values. This will be accomplished though an adaptive management framework that is outlined in the Final Environmental Assessment. The framework provides the BLM the ability to make adjustments to meet desired conditions based on monitoring at the site.
Public interest in the Wave has grown exponentially in recent years. In 2018, more than 200,000 individuals applied for the 7,300 hiking permits available annually to access the site. With only 20 people allowed each day through both the online and walk-in lotteries, only 3.6 percent of applicants were able to obtain a permit to access the Wave. This prompted the BLM to explore options for expanding visitor access in a manner that protects the character of the site and its unique natural features.
While the increase in visitors at the Wave (a feature which is less than half the size of a football field) will be apparent to hikers, there are ample opportunities for solitude that are available away from the main route and outside of the Wave within the more than 112,500 acres of the Paria Canyon–Vermilion Cliffs Wilderness. Additional wilderness values including primitive and unconfined recreation, natural sights and sounds, remoteness, freedom, risk, and the physical and emotional challenges of self-discovery and self-reliance can be enjoyed on the route to and at the Wave.
The BLM's Final Environmental Assessment and Decision Record approving the change are posted on BLM's ePlanning website at: https://go.usa.gov/xyxtK. Learn more about visiting the Wave or the online permit system on our website at: www.blm.gov/TheWave.
Arizona Strip District Office
Rachel T. Carnahan, Public Affairs Specialist
rcarnahan@blm.gov
Coyote Buttes North (The Wave)
Vermilion Cliffs National Monument


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Audi A6 2002 Owner Manual can be very useful guide, and audi a6 2002 owner manual play an important role in your products. The problem is that once you have gotten your nifty new product, the audi a6 2002 owner manual gets a brief glance, maybe a once over, but it often tends to get discarded or lost with the original packaging.


Historical Significance: Ian Bailey graduated as an optometrist in 1961 in a remarkable class of 6 students that included Ian Bailey, Donald Mitchell and Anthony Adams, all of whom pursued academic careers and were appointed professor, Adams and Bailey in the School of Optometry at the University of California Berkeley, where Adams served as Dean, and Mitchell in the Department of Psychology at Dalhousie University, Halifax, Canada, where he served a term as Head of Department. The class that included Bailey, Adams and Mitchell was the second class to qualify for the BAppSc in optometry of the University of Melbourne. Bailey travelled overseas studying in London where obtained the honours diiploma of the Fellowship of the Brtish Optical Association, and at Indiana University where he obtained a master's degree. He returned to Melbourne as lecturer and clinic administrator in the Victorian College of Optometry in 1971. He took the lead in establishing the low vision clinic at Kooyong in 1972 and subsequently established himself as a world leader in the field of low vision. In 1974 he resigned his lecturership in the VCO to become the first research fellow in the then newly established National Vision Research Institute, where he researched the management of low vision, in the course of which he devised the LogMAR system for visual acuity. He subsequently took a position in the School of Optometry at the University of California Berkeley wher he became professor of optometry. His biography is published in Clin Exp Optom 2004; 87: 37-41 and is also on this web site under the tab 'People who made history'.


Finally came one of the most anticipated moments for lovers of good food, for the great fans of gastronomy with capital letters: the start of the almadraba red tuna season , also known as red gold of the sea. A product desired by haute cuisine and the most coveted and desired by the Japanese market.
Currently, around it, an authentic tourism industry has been created, attracting thousands of visitors every year. In addition, both large restaurants and the most renowned chefs in the world turn their eyes to the coast of Cádiz these days.
But what is Almadraba Wild Red Tuna? What is this fishing gear? and Why do we have to come to Conil during these days?
Every spring, wild tuna cross from the Atlantic Ocean to the Mediterranean Sea through the Strait of Gibraltar in search of warmer waters. And it is there, in the sea, off the coast of Conil, Barbate, Zahara de los Atunes and Tarifa, where the almadrabas (word of Arab origin that means place where you fight) are placed, a spectacular fishing gear, which has its origin in the Conil of the Phoenician era. Formed by labyrinths, the tuna is cornered and the fishers execute the call "levantá", which consists in removing the tuna from the trap.
Once the first lift is made, these municipalities are transformed into a true gastronomic epicentre of first level, where the most prestigious names of the restoration meet in search of the best captures and, of course, to savour the exquisite dishes that are cooked with This product of the highest quality.
And the party begins. We must celebrate the arrival of this highly anticipated guest. In each of these almadraberos villages gastronomic events are organized, where you can taste a flood of the most diverse tapas, as a cult to this select product. And it begins, neither more nor less, than in Conil, in whose municipality is Villas Flamenco and where, since May 4, takes place the XXI Tuna Route of Almadraba, which runs until June 4. Here a total of 36 bars and restaurants offer the most exquisite dishes of both traditional and innovative cuisine. Tuna with onions, tuna in mango and avocado ceviche, tuna in tartar with crunchy seaweed, raw tuna, tuna with mushrooms sautéed and oyster sauce, red curry from red tuna mormo, tuna belly with prawns from Sanlúcar, tuna in lard or red tuna sausage, are some of the three hundred ways to taste this delicious delicacy.
Of course, enlivened with good music, exhibitions, dramatized routes, sports, and conferences. And all of this, absolutely everything, revolves around tuna and the sustainable and ancient fishing art of the almadraba.
A note: it is essential not to miss a ronqueo: the traditional way of cutting the tuna and whose name derives from the noise made by the knife when it touches the backbone of the piece.
For those tireless tuna, a few kilometres from Villas Flamenco and Conil is located Barbate, where from 9 to 13 of this same month of May, is celebrated in its "Lonja Vieja", the 11th gastronomic week of almadraba tuna, an event with a very complete programming and with more than popular prices. For just 3.5 euros, you can enjoy a drink and a tapa, the latter, as it could not be otherwise, is based on tuna. Do not forget that in this neighbouring municipality of Conil, the El Campero restaurant is located, known by connoisseurs as the almadraba red tuna temple.
And we go on! A few days later, on the 16th of May the X Tuna Route of Zahara de los Atunes starts, ending on the 20th. A unique occasion also to know and enjoy the atmosphere of this well-known tourist destination. And finally, from the 25th of May to the 3rd of June the VI Tuna Route of Tarifa is celebrated.
Impossible to miss it. Impossible to stop living this experience and not enjoy these delicious dishes. In Villas Flamenco we offer different possibilities to combine these moments of culinary leisure with rest. So, you can choose between the exclusive Villas on the beachfront of Villas Flamenco Beach at Fuente del Gallo or the relaxing oasis of rural accommodation with the charm of Hacienda Roche Viejo or maybe you prefer the holiday apartments of Villas Flamenco Rentals, just a short walk from the vibrant centre of the city.
Do not think twice, Conil is your destination in May and Villas Flamenco your accommodation in Conil for a few days or a weekend getaway. We are waiting for you!
Previous PostPrevious Fairs, Horses and Motorbikes. May, guaranteed party.


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Becoming carepartners
Some people are shocked when they receive an MS diagnosis or develop new, debilitating symptoms, says occupational therapist Laura McKeown, PhD, who has researched the experiences of MS caregivers and teaches at the University of Ulster in Northern Ireland.
"Until the person with MS can accept they have this lifelong condition, they aren't going to be open to having any support," McKeown says. Likewise, caregivers need to be ready to offer support, she says.
Accepting the disease also prepares those with MS and their loved ones to make tough decisions around necessary work and lifestyle changes, says rehabilitation psychologist Kevin Alschuler, PhD, who counsels people with MS and their families at the University of Washington School of Medicine in Seattle. He encourages them to develop a flexible mindset and think beyond "what I have always done," and try different approaches to achieve their desired outcomes.
"Flexibility is not just about, 'What do I do about fatigue today?' but, more broadly, 'How do I adjust to a new symptom later?' " he explains. "We as humans often don't do particularly well with uncertainty, unknowns, constant changes. We like to stick with our strategies that have always worked."
Michael Nesson, left, who has MS, and his partner, George Willey, practice mindfulness exercises to help cope with ups and downs.
Photo courtesy of Michael Nesson
Michael Nesson of Newburyport, Massachusetts, and his longtime partner, George Willey, compare living with MS to playing Whac-A-Mole. "We wonder what's going to pop up next and how we are going to tackle it," says Nesson, 54, who was diagnosed in 2009.
With a sense of humor and flexible mindset, the two work through exacerbations of Nesson's constantly changing symptoms—which include fatigue, left-side weakness, and vision and vocal changes—and through the effects of his disease-modifying treatment.
On Fridays, Nesson injects his medication, which produces flu-like symptoms all weekend and leaves him feeling more fatigued and emotionally worn out by Sunday night.
"He wants less of my help," during those days, Willey says. "When I say something that (upsets) Michael, he can shut down. I used to pull my hair out. I'd think, 'What happened?' "
After two years struggling through these challenges, Willey has learned that when a conflict arises during those three days, it's best to either let it go or bring up the problematic subject later.
Alschuler sees similar situations play out in his practice. He worries when side effects of a medication significantly interfere with relationships. He also commends Nesson and Willey's flexibility: "It sounds like they are wrestling with whether this is the right medication going forward. But in the meantime they are learning how to cope effectively with the side effects."
Both Nesson and Willey practice mindfulness exercises, which Willey says helps him to remain flexible and prioritize all that's on his plate: "I am more calm, centered."
The partners, who have an adult son, know their days are numbered in the 225-year-old home they renovated together. They will likely trade out their dream of retiring in Florida for a ranch-style house in Massachusetts in order to maintain continuity of care with Nesson's doctors there. While the two lament this loss, they focus on positives in their lives.
"Michael is always going to have health challenges and I will always be willing to be a carepartner," Willey says. "The best and strongest thing we have going is our 30-year relationship."
Intimacy creates trust
Talking about the challenges of living with MS—including losses such as retirement plans gone awry—nurtures intimacy, which in turn encourages more communication and builds trust, Rzeszut says. "Each person needs to state what their needs are to the other person, their challenges, what is making them anxious or worried," she says.
As well, couples need to establish emotional intimacy before they can define what physical contact feels good, Rzeszut says. If couples no longer can enjoy a full sexual relationship, they need to acknowledge that loss, then talk about what does or does not feel good to each of them.
"You have to love what you have and let go of what you don't, or it will just drive you down," Patti Berry says. "Intimacy for us is communication, laughter, holding hands, holding each other. And that's OK."
Kelly Pate Dwyer is a freelance writer in Denver.
For more information on how you and a partner can foster positive communication, call 1-800-344-4867 and ask for the Society's Relationship Matters workbook.
How has your relationship changed as a result of MS? Discuss it with others at MSconnection.org.
Tags: Fall 2014


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Orano
With people at the heart of our business, we are committed to the highest standards of safety, quality and welfare. Read more about our values.
Our ethos aligns with the Orano values of customer satisfaction; continuous improvement; respect and people development; exemplarity, integrity and responsibility; cohesion and team spirit. Building on these values, we have fostered a working culture that prioritises safety, performance and respect for everyone we work with, whether this relates to our clients, partners, or our own staff.
As a company operating extensively in the nuclear safety sector, we consider health and safety to be a crucial part of life in the company, whether this relates to the way which we engage with our staff, subcontractors or customers. As a result, we have a vibrant safety culture within the business, and have been awarded the Royal Society of Prevention of Accidents (RoSPA) Gold Award for the past three years running for our commitment to safety in all our activities.
Orano Projects Limited is dedicated to providing a professional service to the highest possible standards of quality, and operate a Quality Management System certified to ISO 9001:2015. With robust internal review structures, and a track record of high-quality output, we work to ensure that our services and deliverables meet the standards required by our clients.
Having developed the reputation of our business over four decades in the nuclear industry, Orano Projects Limited invests in its reputation as a high-quality resource to its clients, by working hard to deliver a consistently thorough, efficient and friendly service to clients. We have a strong service ethos and recognise the importance of delivering an excellent standard of technical and non-technical service in sustaining our future.
At Orano Projects Limited we value our all our working relationships and recognise the importance of partnering in our work. As a company that integrates its engineering and consulting teams to optimise project delivery, and as a signatory to the NDA Supply Chain charter, collaboration is an essential part of how we operate, and as such we work in close partnership and alignment with several national and international organisations to address some of the UK's most complex nuclear challenges.
Welfare and responsibility
Orano Projects Limited takes as many steps as possible to ensure the health, safety and welfare of its staff. We consider ourselves as a friendly company and we care for our staff, their development and well-being in and out of the office. As such we recognise and respect the rights and responsibilities of everyone who works for us, and every aspect of the environment that surrounds them.
Innovative collaboration on one of Sellafield's highest profile projects: Orano's project team features in industry news
Orano's project team, working as part of the ADAPT consortium, has been recognised in the NIA and Britain's Energy Coast Business Cluster news this week in recognition of their role...
New Chief Executive Officer and Country Director for Orano UK
For the start of 2020, Orano UK welcomes a new Country Director and Chief Executive Officer, Stephane Compere.
Applications now open for Orano Projects' 2020 Graduate Scheme
Orano Projects is excited to announce that applications are now OPEN for our 2-year Graduate Scheme, offering you the opportunity to join a multidisciplinary technical consultancy business and work across...
Please get in touch for more information
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RMC: Quick and Concrete Solution
India's infrastructure thrust, stringent deadlines, reviving economy, rebounded real estate are all the positive signs that indicates promising growth for ready mix concrete (RMC) in India. Read on to know of this emerging sunshine industry
After water, concrete is the most widely used substance on Earth. That way google search says. Now, what is concrete? Concrete is binding agent. It binds bricks together and strengthen the constructed structure be it beams, columns or walls. How is a concrete made? It is made mixing cement, water and aggregates (rock, sand, or gravel). We all have noticed while passing through construction site labourers making concrete manually at the construction site. Then there are semi-automatic and automatic concrete mixer which are deployed onsite in mid-sized construction sites. There are trucks fitted concrete mixer which carries concrete to large sites. The concrete carrying trucks have to reach the site on time else the concrete inside the concrete mixer will be harden and of no use. For very large construction projects, such as construction of dams, roads and highways projects, tunnelling projects, large housing projects, concrete batching plants are widely used. These batching plants mixes cement, water and aggregates in huge quantities in a controlled environment with the aid of latest technologies. These plants are either stationary or mobile. The mobile concrete batching plant can be dismantled and assembled at a new construction site. From the batching plants, concrete is carried to the nearby site through concrete mixer truck.
Increasing market share
It is a fact without concrete construction is impossible. Now, with government's stringent deadline for completion of projects the industry is more and more relying on ready mix concrete. Ready mix concrete popularly known by its acronym are manufactured in batching plant in a controlled environment to a given set of proportions, and then delivered to a work site, by truck mounted with mixers. According to a report Indian ready mix concrete market size was estimated at over USD 15 million in 2020, and the market is projected to register a CAGR of over 9% during the forecast period (2021-2026). The demand for ready mix cement is increasing. Take realty project or a redevelopment project in metros and capital cities which has to be completed within the decided timeframe as per RERA laws, else the builder will to pay heavy penalty. Because of the paucity of space to put a batching plant, concrete is carried at site through concrete mixer trucks. There is no alternative. If the builder goes for mixing concrete at site manually, he will definitely mix the deadline. This has given increase boost to RMC. According to TechSci Research, India's RMC market was valued USD 2378.11 million in FY2020 and the market is forecast to grow at CAGR of 16.21% during the forecast period. "The RMC sector in India is growing rapidly at a pace of 15-20 per cent annually," says Anil Banchhor, Managing Director & Chief Executive Officer, RDC Concrete. Like all other industry the RMC industry too was badly battered by Covid-19 has bounced back. The partial opening of lockdown along with resumption of infrastructure and realty project helped in the revival of RMC sector. "The RMC market is on its path to a steady recovery after the tumultuous first and second waves of the pandemic. The first lock down resulted in the stalling of all ongoing projects, construction activities had come to a complete halt. The initial period where everyone struggled to find a foothold amidst the pandemic impacted the industry significantly. Businesses were able to overcome the situation only after the lockdown was lifted, which led to the resumption of economic and construction activities across regions, and the building materials industry also got back on its track gradually. The overall demand is seeing an increase thanks to the resumption of construction projects across regions. Other construction activities are also resuming gradually," says Ashwin Reddy, Managing Director, Aparna Enterprises.
"Despite the initial downturn due to Covid-19, the Ready-Mix Concrete or RMC market in India is now seeing steady growth. With a valuation of USD 2378.11 million in FY2020, it is expected to grow at a healthy pace of 16.21% by FY2026. This recovery is projected on the basis of the construction and infrastructure industry picking up as normalcy returns. This period has also seen a rising awareness of ensuring innovation through Value Added Products, especially in ensuring sustainable construction. With limited resources, concrete products with lesser carbon footprint would gain higher acceptance from both the consumers and regulatory bodies," Prashant Jha, Chief Ready-Mix Concrete Officer, Nuvoco Vistas Corp.
New RMC in the Market
R&D is continuous process, so in research in RMC. There are few mindboggling researchers that are going on such as to come up with RMC keeps the house cool, at least two-degree cooler than outside. Then there are water absorbing concrete useful to drain out water during heavy rains. There are RMC which absorbs radiations. This type of concrete is very useful for hospital construction. Then there are concretes specially manufactured for projects near the sea. Godrej Construction has received the 'Green Pro' certificate from Indian Green Building Council (IGBC) for their RMC products such as Enviro TUFF, Xtra TUFF, Easy TUFF and other construction materials such as TUFF Blocks AAC, Recycled Concrete Blocks & Pavers making them beneficial for use in Green Buildings.
Nuvoco Vistas Corp has introduced a number of products under their concrete segment with the overall objective of ensuring high quality, durability, and ease of use while remaining cost effective. 'we have introduced a light-weight concrete named, Structural Xlite. With a density of around 800-1,600 kg per cm3, it is significantly lighter than typical concrete which weighs in at a density of 2,400 kg per cm3. Lighter weight translates to ease of application and less utilisation of resources, bringing down the cost," says Prashant Jha. The company has also introduced specialised versions of concrete to meet specific demands."we have developed radiation-proof concrete solutions for cancer hospitals. Similarly, another variant can withstand extreme temperatures with improved resistance to water. We have focused on rationalising the usage of water and manpower in our concrete products. Our recent innovation in wet concrete is a step in that direction. It can be poured onsite without any additional water. At 8 hours, it also has a longer retention time than the typical retention time of 4 hours, allowing for longer transportation or application time," says Prashant Jha.
RDC Concrete has wide range of product portfolio for providing high-quality tailor-made solutions for various needs. Greencrete, Duracrete, Crackfree, Naturecrete, Selfcrete, Tempcrete, Supercrete, Fastrackcrete, Fibrecrete are some of the tailor-made concrete offered by the company.
Roadblocks and Traffic Snarl-ups
Like all other industries, RMC industry too faces galore of challenges. "A key factor that impacts the demand for RMC is the increase in the prices of raw materials. Fluctuation in cement prices is also a key factor impacting the industry. Rising fuel prices coupled with cost rise in the supply chain transportation are also aspects that influence the industry's revenue and growth. Decline in availability of cash or cash flow also affects the demand-supply chain for commercial and residential constructions which has direct impact on the RMC industry," says Ashwin Reddy. The challenges expressed by Ashwin Reddy is seconded by Prashant Jha. "The biggest challenge facing the industry today is in the area of resource procurement, both in terms of raw material and manpower. There is a crunch in the availability of high quality materials, which impacts our production volumes," says Prashant Jha.
Anil Banchhor too is in support to the views expressed by Ashwin Reddy and Prashant Jha. He opines, "One of the major challenges in Real estate sector in large metros, is the liquidity issue. This is sure to impact the RMC industry and all major players will need to refocus their growth plans for tier 2 and 3 cities which are still witnessing a steady growth.Another major challenge is uninterrupted supply of raw materials specifically aggregates of consistently good quality required to manufacture ready mix concrete due to several small size unorganised players instead of major branded players.
The race is to save the environment from release of harmful gases that degrades it. Carbon dioxide being one of them. Cement manufacturing release huge amount of carbon dioxide. Concrete being associated with cement authorities have regulated putting of batching plants outside the city limits. This is denting the profitability of RMC manufacturers. From batching plants transporting concrete through truck mounted concrete mixer (RMC trucks) to construction site in heavy traffic is a daunting task. Because of heavy traffic there are times when concrete gets harden and is rendered of no use resulting in loss for the RMC manufacturers. "Apart from the various government clearances which are required to start projects, growth of India's ready mix industry has been baffled due to factors like traffic restrictions and congestion on the road are a major impediment for supply of the product which has a short shelf life of three to four hours from the time of production at batching plant. Setting up commercial plants in metro cities is a challenge due to space constraints and traffic regulations. The civic bodies need to allocate specific locations within the city limits to allow RMC operators to meet the growing demand of urbanisation," says Anil Banchhor.
On setting up of batching plants outside city limits, Prashant Jha says, "Our other challenge comes from local norms and rules that can prohibit the establishment of batching plants in urban areas. It means that concrete has to be transported over long distances from the batching plant that are sometimes outside city limits. Given the perishable nature of concrete, this can be difficult to manage. It also increases the overall costs and the carbon footprint".
Like other industries RMC industry too is facing shortage of skilled manpower. "The industry has also changed rapidly and needs skilled workers, which has again proven to be quite difficult, especially during the immediate aftermath of the pandemic when there was an overall shortage of labour," says Prashant Jha.
Opportunities galore
India has recovered rather quickly from the Pandemic and is on the move. The recent milestone of one billion vaccination to guard its citizen from Covid-19 virus has come as an antidote to the reviving Indian economy. Time and again the state government and the central government has announced stimulus packages for the real estate sector. There are plenty of real estate projects that are in pipeline. A major chunk of concrete is consumed by the real estate sector. Then there are plenty of infrastructure projects which have to be completed with the given timeframe. The prime being twenty million housing for urban poor by 2022. It is in urban parts of India RMC will be in great demand. Paucity of space will limit mixing concrete on site and stringent deadlines will make RMC a must for completing projects on time. Then there are metro projects, 100 more airports to construct across the country by 2025, smart city projects, roads and highways projects, Sagarmala project, which will fuel the growth of urban infrastructure and construction development in the country, which in turn will fuel a promising growth for the RMC sector.
Abhijeet Gawde, Head of Business Development & Marketing, Godrej Construction, says, "As per industry reports, in developed countries, the penetration of RMC is approximately 65 to 70% as against the estimated penetration of 7% in India".Here lies the opportunity to bridge the gap at least by a few percent. Projects are plenty. It is now up to the RMC players to grab the opportunity and move ahead.
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Despite being home to so many historic attractions, London is a city that is constantly changing and evolving. But one of its boroughs seems to have transformed more than all others – the London Borough of Hackney. Set in Inner London, it was ill-famed for its high crime and deprivation rates. Luckily, the borough has managed to change for the better in the past two decades. The fact that Hackney was also one of the host boroughs of the 2012 London Summer Olympics also ushered in a much-needed improvement and gentrification across its districts.
Hipsters are crazy about places that were once downtrodden, overlooked and even dangerous. That is why two of their most favourite districts in the Borough of Hackney are Shoreditch and Upper Clapton. Part of the former was even nicknamed "Murder Mile" because of the many murders and attacks that took place there. These days, however, any licensed man with a van in Upper Clapton E5 will tell you that the area is a top choice for families because it offers decent secondary schools and because things have finally managed to quiet down here thanks to the improvements made prior to the 2012 Olympics.
Shoreditch's story is a bit different. It has never been a district with an extreme crime rate. In fact, for many centuries it was considered to be London's main entertainment area. Unfortunately, Shoreditch's popularity started to decline in the early 20th century and many of the theatres and music venues here were shut down. Since the mid-1990s, however, things have started to take a better turn for the district. Various gentrification projects have been successfully completed here in the past two decades and the results are more than obvious. If you want to relocate to this part of Hackney, look for a home in its eastern part which is more residential. But even if you prefer to move to the west of the area, you will still be able to find affordable man and van services in Shoreditch N1 carried out by licensed and insured moving companies.
It is estimated that Hackney ranks among London's most multicultural boroughs. Districts such as Stamford Hill and Stoke Newington can easily prove that. Stamford Hill, for instance, is a place where you can find the greatest number of synagogues in London per square mile. That is because this neighbourhood is home to the biggest Jewish Chasidic community in the country. But you do not need to be Jewish to appreciate the spacious and grand 18th-century properties in the area. Still, you will need to hire an experienced man with van in Stamford Hill N15, N16 if you want to enjoy a hassle-free moving experience.
Stoke Newington is even more multicultural than Stamford Hill since it is inhabited by people of Irish, Jewish, Turkish, Afro-Caribbean, etc. descent. Stokey, as locals like to call it, is a currently a big hit among young families because it packs a lot of history but, at the same time, it offers a wide selection of quality bars, clubs and restaurants. Therefore, if you decide to book a skilled man and van in Stoke Newington N16 and to move here, you will enjoy the best of both worlds.
The word that the London Borough of Hackney is no longer a risky and deprived place still has not reached a lot of people out there. That is why many of the areas which are set within its boundaries can be called hidden gems. Such is the case, for instance, with South Hackney. Even though an increasing number of companies and home-hunters express interest in it, it remains a considerably budget-friendly area. But that is not expected to be the case for long. So, if you want to relocate to a popular and hip borough like Hackney, find yourself a speedy man and van service in South Hackney E9 and start packing.