An analysis of ECMO – extracorporeal membrane oxygenation – use in patients with cardiogenic shock finds that mortality remains high despite increasing utilisation of the resource-intensive intervention in this population. Season of admission (other than Fall) and presence of specific comorbidities (respiratory and genitourinary diseases) are associated with the high death rates in these patients, according to the study published in the journal BMC Emergency Medicine.
"In addition to previously described associated clinical variables, the study examined different socio-economic and system level factors that might be affecting mortality in this population," study authors write. "Familiarity with patients' characteristics and variables associated with mortality after ECMO use is important to improve outcomes further in cardiogenic shock."
ECMO or extracorporeal life support (ECLS) is a sophisticated and resource-intensive intervention for critically ill patients with cardiac or respiratory dysfunction. ECMO use improves survival in patients with cardiac disease with survival rates ranging from 20 to 50 percent. Few studies describe ECMO use in cardiogenic shock. The current study aimed to examine ECMO use and identifies variables associated with mortality in patients treated for cardiogenic shock in U.S. hospitals.
Cardiogenic shock is a clinical condition of inadequate tissue perfusion due to cardiac dysfunction that is associated with persistent hypotension and end organ damage. Cardiogenic shock often results from myocardial infarction but can also result from other cardiac diseases such as myocarditis, pericarditis, and cardiomyopathy.
Researchers conducted a retrospective observational study of the U.S. Nationwide Emergency Department Sample (NEDS) database of 2013. Weighted visits for cardiogenic shock (discharge diagnosis) with ECMO use were included. Collected data was analysed and variables associated with mortality were identified.
A total of 922 weighted patients (mean age was 50.8 years; mostly males [66.3%]) with cardiogenic shock and ECMO were included in the analysis. Slightly over half (51.0%, n = 506) survived to hospital discharge. Mean charges per patient were $589,610.5; mean length of stay was 21.8 days.
Increased mortality was associated with presence of respiratory diseases (OR = 3.83), genitourinary diseases (OR = 4.97), undergoing an echocardiogram (OR = 4.63), and presenting during seasons other than Fall. Lower mortality was noted in patients with injury and poisoning (OR = 0.47), in those who underwent certain vascular procedures (OR = 0.49) and those with increasing length of stay (OR = 0.90).
"Seasonal variation in mortality among patients presenting with cardiogenic shock and undergoing ECMO procedure was also identified in this study," the authors say. "Reasons for these seasonal variations though not directly identified in our study are multiple and complex, involving both physiologic and behavioural causes. Previously identified causes include sudden cold acclimatisation, change in dietary patterns, change in physical activity, changes in mental health, vitamin D deficiency, increased air pollution, and increased incidence of infectious disease."
ECMO is just one of several mechanical assist devices used in cardiogenic shock. Other devices include intra-aortic balloon pumps (IABP) and LV assist devices (LVADs). ECMO, however, is the only intervention that compensates for both the right and left heart function as well as lung function. The authors explain: "ECMO decreases requirements for catecholamine, vasodilator, and mechanical ventilation in the treatment of cardiogenic shock and reduces the complications that are usually associated with these treatment modalities. ECMO use therefore holds promise for use in selected cardiogenic shock patients and further prospective studies are recommended."
High-risk ECMO - heroic rescue or futile care?


Fernão Mendes Pinto, (born c. 1510, Montemor-o-Velho, Port.—died July 8, 1583, Almada, near Lisbon), Portuguese adventurer and author of the Peregrinação (1614, "Peregrination"; Eng. trans. The Travels of Mendes Pinto), a literary masterpiece depicting the impression made on a European by Asian civilization, notably that of China, in the 16th century.
Pinto went to India in 1537 and later claimed to have travelled, fought, and traded in almost every part of Asia during the next 21 years and also to have experienced drastic reversals of fortune, having been made "13 times a prisoner and 17 a slave." In China, for example, he was convicted of plundering royal tombs and, as punishment, had his thumbs severed and was sentenced to a year of hard labour on construction of the Great Wall. The Peregrinação was written after Pinto's return to Portugal in 1558. He settled in Almada, married, and received a pension from King Philip. Pinto's Peregrinação is of no geographic value, but it is of great interest as depicting the impression made on an intelligent Portuguese by the civilizations of the Far East and for its thinly veiled criticism of the behaviour of his compatriots in Asia. It became widely popular and went through a number of editions in the 17th century.


It was during 1753 that Lord Hardwicke addressed the Houses of Parliament, proclaiming the necessity to make 'irregular' marriages illegal and to bring marriage under the regulation of the church.
The result of this was the 1754 Marriage Act - the wedding ceremony now had to take place in Church and couples had to be 21 years of age to marry without the consent of their parents, previously no consent was required if you were above the age of 16.
Hardwicke's Act was introduced in order to try to bring control into the many irregular marriages that were taking place all over Britain, often involving seduction, bigamy and fraud.
One of the most notorious of those places was the Fleet Prison in London. On the day before this new law came into force, 26th March 1754, there was a rush to beat the deadline and it is recorded that 217 weddings took place at Fleet Prison and its surrounds!
Scotland's refusal to adopt the Act created a loophole for youngsters determined to marry. Scots and English Law Lords debated the issue for 186 years before the Scots relented and outlawed 'handfasting' ceremonies but this was a legally binding marriage ceremony until 1940.


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Tatjana Petrenko (ryska: Татьяна Дмитриевна Петренко-Самусенко), född den 2 november 1938 i Ostrosjitsj, Vitryssland, död 24 januari 2000 i Minsk, Vitryssland, var en sovjetisk fäktare.

Hon tog OS-guld i damernas lagtävling i florett i samband med de olympiska fäktningstävlingarna 1972 i München.

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Sports-reference.com

Sovjetiska fäktare
Sovjetiska olympiska silvermedaljörer
Sovjetiska olympiska guldmedaljörer
Olympiska guldmedaljörer 1960
Olympiska silvermedaljörer 1964
Olympiska guldmedaljörer 1968
Olympiska guldmedaljörer 1972
Tävlande vid olympiska sommarspelen 1960 från Sovjetunionen
Tävlande i fäktning vid olympiska sommarspelen 1960
Tävlande vid olympiska sommarspelen 1964 från Sovjetunionen
Tävlande i fäktning vid olympiska sommarspelen 1964
Tävlande vid olympiska sommarspelen 1968 från Sovjetunionen
Tävlande i fäktning vid olympiska sommarspelen 1968
Tävlande vid olympiska sommarspelen 1972 från Sovjetunionen
Tävlande i fäktning vid olympiska sommarspelen 1972
Kvinnor
Födda 1938
Avlidna 2000
Personer från Minsk oblast

redpajama_set_name: RedPajamaWikipedia


Do you suffer from the January blues? It's understandable. The cold weather feels like it won't let up, work at the office has resumed and those enjoyable festive moments feel long gone. When we feel like that at Casale we do one thing. We leave the house and we head to the orchard.
We watch the sun rise through the trees, we take a deep breath in to catch the scent of the wild mountain herbs after the rain and we take a few minutes to absorb nature at its most beautiful.
The area we now call the Orchard wasn't always a thing of beauty though. Much of our village was left to erode up until the 1980s. It was the father of John, the owner of Casale, who first had the idea to begin cultivating the land. John, who was working abroad at the time would send money back to him, which he used to begin the project. He didn't really plan it properly, but each new addition to the orchard seemed to complement the last.
Now if you take a stroll through the trees you will find oranges, lemons, clementines, pomelo, mandarins, kiwi fruit, grapes, walnuts, peaches and figs. Plus tomatoes, cucumbers, peppers and other veg in the summer. You might even see us picking the thyme, sage and mint for our mountain tea.
In fact, much of the fruit and vegetables served in the restaurants come from the estate. They're even in our cocktails! At the moment the orchard is full to the brim with citrus fruit. So, the jams and marmalades at our breakfast buffet contain oranges and lemons handpicked by us, especially for you.
The first step to a successful orange marmalade is taking advantage of the pectin in the oranges (a natural gelling agent found in ripe fruit). So on the first day we cut the fruit making sure we remove the seeds, and the next day we make the jam.
Cut the oranges and lemons into big pieces.
Place all the fruit pieces into a large non-stick or stainless steel pot. Add the water and bring to a boil.
Remove the pan from the heat and put the boiled fruits into a blender.
Place the mixture in a pan, add the sugar, stirring well until the sugar is dissolved.
Place the cover on the pan and let it set overnight.
The next day, bring the mixture back to a boil. Reduce the heat and simmer on low for two hours. Turn up the heat a little and boil gently for 30 minutes. Skim off any foam with a metal spoon.
The jam will set completely after you add it to the jars.
The jars must stay in one place for at least 24 hours.


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Q: Delta indexes not working on servers when using Thinking Sphinx I'm using delta indexing for my Thinking Sphinx indexes in my Rails project. In my machine (Mac OS X) it's working fine. I change a record and it immediately finds it. On the servers (Debian) it doesn't.
I did run a sql query for delta = true and the I've got the expected recently changed records, so that part is working. In the log/searchd.query.log I see the proper request:
[Fri Oct 22 10:25:29.193 2010] 0.000 sec [all/3/rel 0 (0,20)] [customer_core,customer_delta] Jonas4

Any ideas what else could it be?
Thanks.

A: I'll answer here, even though you've posted to the support list as well...
Which user is running the TS rake tasks? And which user owns the Rails site on your server? They should be the same.
Also: are you using Passenger? If so, you'll want to make sure the bin_path setting is set in your config/sphinx.yml file. The documentation runs through both points.
Let me know if neither of these things help matters.

redpajama_set_name: RedPajamaStackExchange


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Mississippi Association of Professional Process Servers
MAPPS Member Benefits
Policy & Procedure Manual
Currently viewing archive for General
MAPPS Approves Recommended Affidavit of Service
by Davy Keith,
Author note: Davy is a charter member and former President of MAPPS (Mississippi Association of Professional Process Servers. Davy is a 20-year veteran of the process serving industry and owner of Quantum Process, LLC (formerly Keith Investigations, LLC).
The question of providing a "court approved" proof of service has been a topic each year at our Mississippi Association of Professional Process Servers (MAPPS) since its inception in 2010. The proof of service provided to your client is essentially the final product that you offer for services rendered. It is of utmost importance that such proof of service is rendered with zero errors. It should be as close to perfect as possible. What will "get by" and what is "correct" are absolutely two different issues. It is important to understand that proofs of service in state courts within the United States usually have their own approved has their own approved form and this tractate is limited to providing a correct court approved proof of service for Mississippi Circuit, County or Chancery Court.
Over the past 20 years of service process, I have gained the knowledge and understanding of what or which form to use for a Mississippi Summons in regards to a proof of service that complies with the form provided in Mississippi Rule 4. The form proof of service listed in "Forms" in Mississippi Rules of Civil Procedure was adopted by the Mississippi Supreme Court Rules committee March 1, 1985. The latest revision was made March 17th, 1995. This form was designed to be copied on the back of any summons issued in any Mississippi Circuit, County or Chancery Court Summons. The form is titled, "Proof of Service-Summons." In my opinion, this form has a few issues.
The first issue I will discuss is that there is no area to include additional documents served in addition to a Summons and Complaint. Often, there is discovery, interrogatories, exhibits, etc that should be listed as served in conjunction with the Summons and Complaint. This form is also lacking the address where such person was served. Often, a summons will have the wording "or wherever he or she may be found." The issue of where such person was served is a question that comes up in court and / or with counsel involved in the case. As previously stated, the form proof of service is designed to be printed on the back of the Summons. This is problematic when the Summons and other documents are served at an alternative location or address than what is provided or listed on the summons. With this form, there is no place for the server to enter the address where the papers were served when it was served at another address unless the server alters or hand writes another address on the summons or makes notes on the back of the summons on the approved form. Both of these options are a poor choice as no summons should be altered in any way after service. The form also has a section to provide the server's social security number. Due to security and identity theft, no court in Mississippi requires that this information be put on a proof of service that is available for public record.
Summons are routinely now being filed electronically. It is no longer necessary to have a "wet ink" summons accompany the proof of service filed in any court in Mississippi. In fact, this causes issues when an attorney or other person sends all of their original summons that were issued by the clerk to the server so that a proof of service may be completed on the back of the summons. If the original "return" summons is misplaced, complications may result as some clerks may or may not keep an original summons on file. There is no law or restriction serving a validly issued "copy" of a summons. Therefore, in my opinion it is not a requirement of Rule 4 to serve a summons by the clerk of court, and / or wet ink seal from the clerk. In my experience, it is now common practice in all Mississippi state courts that a proof of service may be a separate document without having to be printed on the back of an original summons. In conclusion, Rule 4 only gives a form example of the proof of service. I believe that keeping the original wording and language provided in Rule 4 along with all the information requested on the example form, the additional information I have mentioned here is the best practice in providing a proof of service.
Davy Keith with Quantum Process, LLC designed and submitted a proof of service to be used in any Mississippi Circuit, County or Chancery Court that replicates the language and format of the original approved form proof of service previously mentioned. The proof of service covers the issues mentioned previously such as the address where the papers were served along with removing the Social Security of the process server from the form. This proof of service is a "stand alone" proof that includes the style of the case, exact documents that were served, along with needed information. In other words, this proof of service supplies all the required information and more. The wording was copied word for word in regards to the language adopted in the approved form as well as the general layout of the form. There are two separate forms that are used. One that reflects in hand personal service and one that reflects what the approved form calls "residence" service. Since these forms are prepared each time, electronically, there is no reason to have both methods of service listed when only one was achieved. It is important to note that if residence service is obtained, the date of the mailing required by Rule 4 must accurately reflect the date that the papers were mailed, first class postage pre-paid, to the address where the papers were served. This date usually is populated to the date that the papers were served. If this date is after the day it was served, the day must manually be changed so that the proof accurately indicates the date of the mailing of the copies after service.
These proofs of service were presented to the board members of MAPPS and were approved as the best proofs of service to use for Mississippi Circuit, County and Chancery Court as they not only comply with the needed language offered on the approved form but also include additional information that allows the proof to be presented as a stand alone document not required to be printed on the back of the summons served. MAPPS recommends that any service validly issued in any Mississippi Circuit, County or Chancery Court use this approved form for all proofs of service served personally or with residence service.
These "MAPPS-approved" proofs can be found at the links below:
Mississippi – Residence Proof of Service (MAPPS-approved)
Mississippi – Personally Served Proof of Service (MAPPS-approved)
These affidavits are also available in ServeManager. If you have a ServeManager account and you want access to these proofs, please contact ServeManager here to make them available in your account.
Professional Process Server Verifiable Identification
In several jurisdictions throughout the Unites States, including Mississippi, the identities of persons authorized by court rule, or statute, to serve civil process are not readily available for public verification. Many of these jurisdictions do not require it, and simply allow for persons 18 years of age or older, who are not parties to the particular civil action that is being served, to serve the process. No registration or licensing is required.
As part of their duties, private process servers interact with various segments of their communities on a daily basis. Often, their identification as process servers is requested, or required.
PPSVID.com, established by PPS Collateral Services, allows for a voluntary enrollment of private process servers within their respective jurisdictions to make public their qualifications and identity. The process servers who voluntarily enroll are provided with standardized, verifiable identification cards. These may be viewed when presented to a requesting party, and can be further verified online by scanning a QR (Quick Response) Code on the card, or by selecting a "Click to Verify" button on a website. The response will be a similar image as that appearing on the identification card, and that person's current status and relevant information.
For enrollment forms, requirements, and applicable fees, email request to [email protected]
Process servers case before Miss. court
JACKSON, Miss. — The Mississippi Supreme Court will review contempt of court citations filed by a judge against three people who allegedly lied about delivering subpoenas in child support cases.
In July of 2010, Jackson County Chancellor Neil Harris found Guy Jernigan, Thomas Corey McDonald and Edwin Cheshire in contempt of court for filing false affidavits and ordered them to pay $88,500 in sanctions and serve jail time until the money was paid.
In court documents, Harris has said Jernigan claimed he served a woman who was in jail and couldn't receive a subpoena and another who had been dead for two years.
Jernigan and McDonald were process servers for First Fidelity Trust Services Inc., a subcontractor of YoungWilliams Child Support Services. Cheshire is identified in court documents as president of First Fidelity Trust.
All three appealed to Harris' order to the Mississippi Supreme Court.
According to Harris' order, Jernigan filed a sworn affidavit with the court clerk stating he served April Gray of Ocean Springs on May 6. But Gray was jailed at the Jackson County Adult Detention Center at the time and could not have received the document.
YoungWilliams is a Jackson company that had a $23 million with the Mississippi Department of Human Services to seek child support court orders.
The process servers claimed they delivered papers to people who were incarcerated and even to a woman who had been dead for two years, court records show.
Questions about the process servers prompted an investigation by MDHS.
The case is among dozens of appeals before the Supreme Court in its July-August term. The Supreme Court will not hear oral arguments in the case.
Read more here: http://www.sunherald.com/2012/07/10/4053848/process-servers-case-before-miss.html#storylink=rss#storylink=cpy
National Due Process Day
Join MAPPS in celebrating National Due Process Day on September 25th (9/25/2012). National Due Process Day is a public awareness campaign aimed at ensuring that every American's right to a fair trial is preserved. The Bill of Rights guarantees that no person shall be, "deprived of life, liberty or property without due process of law." The 14th Amendment further expands upon The Bill of Rights.
Constitutionally protected rights such as "due process of law" are integral to several professions including: attorneys, the courts, and professional process servers. MAPPS is one of the many groups committed to protecting the constitutional rights of citizens.
Service of process is an important step in upholding one's constitutional rights. By notifying the party of pending legal action, process servers play an important role in ensuring that due process of the law occurs.
If you would like to join us in celebrating National Due Process Day, please call 1-800-477-8211.
More Information: [PDF]
Process Servers Are Preferred
ServeNow conducted research that found process servers are preferred to sheriffs for a number of reasons, which you can see below. If you are looking for a Mississippi process server, you can search our members.
Read more at ServeNow.
MAPPS Site Goes Live
The new MAPPS website is now online. The site is designed specifically to increase the number of MAPPS members, allow for communication at both a local and national level, as well as, disseminate relevant and timely news and information.
The website itself was designed with the end-user in mind. The MAPPS site is intended to be user-friendly and easy to navigate. Moreover, the website features an aesthetically pleasing and clean look. In terms of functionality, the website enables administrators from the association to update content quickly.
The MAPPS site features association-specific sections including:
-News about the Association
-Member sign up
-MAPPS blog
-Member directory
-Events section
-Vendor advertising
-Contact information
With this new website, MAPPS has an online destination where process servers nationwide can find information, apply for membership, find other process servers to forward papers and much more.
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redpajama_set_name: RedPajamaCommonCrawl


text:
GEGOOGMSFTMCDCMGYUMAMRK
Ugly Earnings from Majors Like Microsoft and McDonald's Hit Wall Street
Andrew Klips Follow
| Friday, 19 October 2012 06:00 (EST)
Google (GOOG) released a disappointing earnings report on Thursday that helped guide the tech-heavy Nasdaq exchange more than 1 percent into the red. Coupling reports after the closing bell yesterday with Friday morning reports, more big board staples are disclosing financials that are coming-up shy of Wall Street's expectations.
Notable laggards resulting from less-than-expected earnings include, Microsoft Corp. (MSFT), McDonald's Corp. (MCD), General Electric Co. (GE) and Chipotle Mexican Grill Inc. (CMG).
Yesterday evening, Microsoft reported a 22 percent drop – from $17.37 billion to $16 billion - in its fiscal first quarter revenue, citing challenges in the broad PC market and lowered inventories of Windows 7 as part of the transition to Windows 8 operating system. Windows 8 is expected to finally debut next Friday.
The Redman, Washington-based tech firm said profits for the quarter equaled $4.47 billion, or 53 cents per share, as compared to profit of $5.74 billion, or 68 cents per share, in the year prior quarter. Analysts were calling-for $16.5 billion in revenue and 56 cents per share in earnings.
The company did defer about $1.35 billion in sales related to it Office software and in pre-sales for Windows 8. Shares fell about 2 percent in early Friday trading from Thursday's $29.50 closing price.
McDonald's also missed analyst predictions by posting a 3 percent drop in third-quarter profit to $1.46 billion, or $1.43 per share. In the year prior quarter, McDonald's reported profit of $1.51 billion, or $1.45 per share. Revenue during the latest quarter edged-down 0.2 percent to $7.15 billion. Analysts were calling for revenue of $7.14 billion and earnings per share of $1.47.
Like many other companies with heavy sales generated overseas, an unfavorable forex market hampered profits. Excluding currency fluctuations, revenue was up 4 percent.
Shareholders of the world's biggest burger chain aren't singing "I'm Loving it" to the latest financials as shares are down more than 3 percent in early trading from yesterday's closing price of $92.86.
Shares of General Electric are down about 3 percent to $22.10 in Friday morning trading after the U.S.'s largest conglomerate posted a 2.8 percent increase in third quarter revenue to $36.35 billion from $35.36 billion the year earlier, but missed Wall Street estimates of $36.94 billion. A weak currency exchange cost earnings $1.1 billion, according to the Fairfield, Connecticut-based company.
GE reported a profit of $3.49 billion, or 33 cents a share, versus $3.22 billion, or 22 cents a share, a year earlier. Analysts were calling for 36 cents per share in earnings.
Chipotle shares are getting crushed by more than 14 percent to $243 each in early trading after providing an earnings miss and weak forecast after Thursday's closing bell. The Denver-based burrito maker notched an 18 percent climb in third-quarter revenue to $700.5 million and a quarterly profit of $72.3 million, or $2.27 per share, compared to $60.4 million, or $1.90 per share last year. The increases missed analyst forecasts of earnings of $2.30 per share and $702 million in revenue.
What hurt Chipotle the most is a deceleration in growth. Once one of the most-loved restaurant plays that regularly posted double digit gains in same-store sales, Chipotle has cooled in growth and its shares have suffered; losing more than 40 percent from April highs of $442.40 a share. Last quarter, same-store sales grew by 4.8 percent, short of 5.4 percent growth analysts expected.
Early in October, influential hedge fund manager David Einhorn, who runs the $7.7 billion fund at Greenlight Capital, call Chipotle's market cap a "nosebleed valuation" and indicated the company was a viable short option as competition for Yum Brands (YUM) stiffens through its Taco Bell restaurants.
Follow	 CMG Chipotle Mexican Grill Inc. 1,405.74 -6.06 -0.43 208,615 Trade
Follow	 GE General Electric Company 11.33 -0.33 -2.83 73,583,131 Trade
Follow	 AMRK A-Mark Precious Metals Inc. 28.52 -0.38 -1.31 55,506 Trade
Follow	 YUM Yum! Brands Inc. 106.62 -1.16 -1.08 1,163,527 Trade
Follow	 GOOG Alphabet Inc. 1,736.19 -3.99 -0.23 1,341,908 Trade
Follow	 MCD McDonald's Corporation 209.91 1.41 0.68 3,593,297 Trade
Follow	 MSFT Microsoft Corporation 212.65 -0.37 -0.17 31,738,185 Trade
Follow Chipotle Mexican Grill Inc.
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June 2018 – For the past year, the MPO's School Transportation Working Group (STWG) has been providing stakeholder input on the development of the methodology, screening criteria and selection of the Top Ten Schools for field reviews. During May, the MPO committees and School District Transportation Committee favorably received the final draft of the MPO School Safety Study and Top Ten Report. The report will be presented to the MPO Board July 31, 2018.
The School Transportation Working Group was also treated to a presentation of the Coleman Middle School Road Safety Project by 6th graders Keely Lueckeman, Sophie Sollenberger, Jack Watkins, and 7th grader Clara Hinsdale. The project was developed and designed to encourage students to observe traffic rules while reaching Coleman Middle School by foot or bicycle.
and wear a bike helmet while crossing the roads around the school safely before school.
The Champions are Coleman student volunteers and parent volunteers. The group has used community engagement to collect the prize donations of student rewards. The student presenters were accompanied by their sponsor, Robert Pechacek, Student Government Advisor, Asst. Principal Nannette Harvey and parent volunteer, Trang Burnett. In addition, they receive support from the Parent Teacher Student Association (PTSA).
The STWG was excited to see Coleman busy implementing the Education/Encouragement piece of safe routes to school concepts. The student's work complement's the primarily Engineering/Enforcement solutions proposed in the MPO School Safety Report.


text:
from django.apps import AppConfig

class CnDeviseConfig(AppConfig):
    name = 'cn_devise'

redpajama_set_name: RedPajamaGithub


Villa Tividavo is located 10 minutes from Ibiza Town, perfect for those who love to be close to the action. The villa has different parts in the garden to chill, a large pool and a sundeck with sofas to enjoy the beautiful view.
The villa has a modern interior design, is very private and offers a lot of comfort.


In this weeks Out of School, Fraser looks at the undesirable effects that new innovations and bring to a social order.
Are larger organizations more innovative than smaller ones? It often depends on who is answering the question, and what the questions were.
In this episode of Out of School, Fraser and Bradley discuss The Chromebook C, the LAUSD settlement with Apple, and chapter 8 and 9 of Diffusions of Innovations.
Consumers fall into one of five adopter categories which determines when they buy new innovations. Most people are considered "Early Majority".
There are five properties that determine the speed a product spreads through a group. These properties include trialability and observability.
Can the iPad Pro replace a laptop? In this podcast two IT educators discuss the pros and cons.
When new innovations are ready, how do consumers decide when to adopt them and how? Is this random or is there a method to the madness?
In the latest Out of School podcast, the hosts talk EdTech: Teaching programming to high school students and why it's important.


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Georgia Governor Brian Kemp greets President Donald Trump as he arrives at Dobbins AFB on Friday, November 8, 2019, in Marietta. Curtis Compton/ccompton@ajc.com
Photo: Curtis Compton
Answered: The top 10 Georgia political questions of 2019
Greg Bluestein
Before the start of 2019, your Political Insiders laid out the nine questions in Georgia politics to watch this year.
We are reprinting that column in full, with answers attached beneath each question. Take a trip down memory lane with us.
(For kicks, here are the 2018 and 2017 versions of this column.)
How will Brian Kemp govern?
Call it the duality of Brian Kemp: He won the Republican nomination with a pledge to move Georgia firmly to the right on a range of cultural issues, including expanding gun rights, cracking down on illegal immigration and signing the nation's strictest abortion controls. He won the general election with the help of broader appeals to buckle down on school safety, hike teacher pay, boost rural Georgia and enact a contentious "religious liberty" bill only under the strictest circumstances. So which Kemp will show up in January? He's pledged he won't abandon the conservative principles that electrified his supporters and helped him eke out a narrow November victory. But he's also told a Legislature that hasn't been this closely divided in more than a decade that he'll focus less on the polarizing issues and more on the pocketbook ones. And he'll face new pressure – from the courts, from Democrats and from his own party – to solve pressing voting rights issues that surfaced over the last year. He'll also have a largely untested team dealing with a host of powerful players that include House Speaker David Ralston – who has solidified control of his chamber over the last decade – and incoming Lt. Gov. Geoff Duncan and a fractious Senate caucus. How he will navigate this high-wire act will set the stage for his first term in office.
Answer: The governor embraced policies that even his more moderate predecessor, Nathan Deal, would not consider. He signed legislation that legalized the sale of medical marijuana, backed a healthcare overhaul that would cover tens of thousands of low-income Georgians — though stopped short of embracing a full Medicaid expansion— and surprised his critics with history-making appointments to top posts. But his most controversial policy achievement during his first year was the passage of stiff anti-abortion restrictions that sparked national attention and led to threats of a Hollywood boycott. Meanwhile, there was little movement on Kemp's other promises to crack down on illegal immigration, expand gun rights and adopt a "religious liberty" proposal. And he triggered tough budget negotiations with a call for 10% budget cuts over the next two years. The end of the year brought his biggest political decision: He tapped finance executive Kelly Loeffler for an open U.S. Senate seat, defying President Donald Trump's push for a conservative lawmaker.
ATLANTA, GEORGIA - NOVEMBER 20: Democratic presidential candidates Sen. Elizabeth Warren (D-MA), is seen being broadcast on television monitors in the media room during the Democratic Presidential Debate at Tyler Perry Studios November 20, 2019 in Atlanta. (Photo by Joe Raedle/Getty Images)
Photo: Joe Raedle/Getty Images
Will Georgia emerge as a legit battleground state?
Let's put it this way: It would be shocking if Georgia isn't squarely on the political map over the next two years as President Donald Trump prepares for re-election and the field of Democrats challenging him takes shape. Let the numbers tell the tale: Eight. Five. One and a half. That's the margin of Republican victories in Georgia by percentage point since 2014. That doesn't mean that Georgia is fated to flip, but it does mean that Republicans will have to play defense in a state that was all but a lock for Republicans over the last quarter-century. In 2016, the "SEC primary" triggered visits from nearly every leading presidential contender before Georgia's vote – but neither Trump nor Hillary Clinton visited after primary. Already, a slate of high-profile potential Democratic contenders has visited Georgia to stump for candidates and shore up their own networks of support here. Expect that to be just a taste of what's to come.
Answer: There's no doubt about it. Even Republican leaders acknowledge Georgia is a battleground and that last year's election was a "wakeup call." Presidential candidates swarmed the state and targeted voters with Georgia-centric appeals that blasted anti-abortion restrictions and promised new attention to voting rights. Each courted Stacey Abrams, the former Democratic gubernatorial contender who penned a memo warning it would be "political malpractice" if Democrats fail to pour more resources into Georgia. U.S. Sen. Johnny Isakson's retirement promised Georgia even more attention; with two Senate seats on the ballot next year, Georgia plays a more pivotal role in Democratic hopes of flipping the chamber. Then came the biggest award: Democrats picked Georgia to host the November presidential debate, selecting a site at Tyler Perry Studios in Atlanta to showcase the party's push to recapture Georgia.
United States President Donald J. Trump and US Senator David Perdue (Republican of Georgia), listen as US Senator Tom Cotton (Republican from Arkansas) makes an announcement on the introduction of the Reforming American Immigration for a Strong Economy (RAISE) Act in the Roosevelt Room at the White House in Washington, D.C., U.S., 2 August 2017. The act aims to overhaul U.S. immigration by moving towards a "merit-based" system. - NO WIRE SERVICE ' Photo by: Zach Gibson/picture-alliance/dpa/AP Images
Photo: Zach Gibson/Zach Gibson/picture-alliance/dpa
Who will challenge David Perdue?
One of the juiciest targets on the Senate map in 2020 is Republican David Perdue, who is running for his second – and he says final – term in the U.S. Senate. The businessman has become one of President Donald Trump's most prominent D.C. allies – even in his most isolating moments – and he plans to stick to the outsider, anti-establishment message that won him his seat in 2014. No well-known Republicans are expected to oppose Perdue in a primary, but several Democrats have hinted they're interested in challenging the multi-millionaire in 2020. Most are waiting for Stacey Abrams to decide her next step after her near-miss in the race for governor. If she sidesteps a 2020 race, Democrats could be in for a tempestuous primary fight from potential candidates that include outgoing Columbus Mayor Teresa Tomlinson, Pastor Raphael Warnock, former congressional candidate Jon Ossoff and ex-Senate candidate Michelle Nunn.
Answer: Four top Democratic candidates have joined the contest, including two named above. Former Columbus Mayor Teresa Tomlinson and investigative journalist Jon Ossoff are each in the hunt. So are Sarah Riggs Amico, the runner-up in last year's race for lieutenant governor, and Clarkston Mayor Ted Terry. Just as significant is who is not in the race: Stacey Abrams, Jason Carter, Sally Quillian Yates and other top Democrats passed on the contest. As 2020 dawns, the bigger question revolves around the other Senate seat: Who will join the race to challenge incoming U.S. Sen. Kelly Loeffler next year?
November 21, 2019 - Atlanta - Stacey Abrams makes some calls at the phone bank. Democratic presidential candidates including Cory Booker, Amy Klobuchar, Andrew Yang and Pete Buttigieg, along with Stacey Abrahms, were calling and texting voters Thursday whose registrations could be canceled in Georgia at a Fair Fight phone bank at Ebenezer Baptist Church in Atlanta. The phone bank was in response to Georgia election officials' plan to cancel more than 313,000 voter registrations next month. Bob Andres / robert.andres@ajc.com
Photo: Bob Andres/robert.andres@ajc.com
What will Stacey Abrams do?
That's the question on the tips of the tongues of most Georgia Democrats. Her campaign for governor earned her dizzying national fame and a cadre of loyal supporters in Georgia and beyond. Since her loss to Brian Kemp – and a non-concession speech heard 'round the world – she launched a new group challenging Georgia's voting laws, joined the board of a progressive think-tank, launched a round of TV ads about healthcare and waded into national debates over ballot access. Some high-profile Democrats want her to challenge David Perdue in 2019, though her allies say she's more likely to aim for a 2022 rematch against Brian Kemp. And she could well end up on some Veep short-lists in the coming years. No matter what she decides, she has plenty of political capital now – and can spend it as a queenmaker in Georgia politics.
Answer: In defeat, Abrams' political star might have soared higher than had she won. She delivered the Democratic rebuttal to the State of the Union in February, snapping a tradition of lackluster responses. In April, she decided not to run for the U.S. Senate but made clear she still had lofty political ambitions. And by year's end, she was seen as a certainty to be on 2020 running-mate short lists. In between, she expanded her Fair Fight voting rights group to 19 other states, launched a group aimed at an accurate U.S. Census count and started a think tank.
Will lawmakers tackle Georgia's voting issues?
Lawmakers seemed to have reached a consensus in 2018 that the state's 27,000 direct-recording electronic voting machines should be replaced with a system that leaves a verifiable paper trail. But what they haven't agreed on is what type of paper-based voting system Georgia should use and how much taxpayer money should be spent. And that's just the start: Incoming Gov. Brian Kemp and a new Legislature will face questions over a slate of other voting issues, including uneven standards for counting provisional and absentee ballots, how to address lengthy lines at early-voting and Election Day polling sites, voter registration cancellations and the state's embrace of exact-match standards. And if lawmakers don't tackle those debates, the courts might do it for them.
Answer: Sort of. Gov. Brian Kemp signed a bill that calls for new voting machines that print paper ballots, extends the time before registrations are canceled and places limitations on precinct closures. But the polarizing debate infuriated Democrats who wanted more significant changes. They pointed to cybersecurity experts who warned it would leave Georgia's elections susceptible to hacking and tampering. The courts still might force more sweeping changes: A far-reaching lawsuit that seeks to solve problems with voting machines, voter registration cancellations and election security is still pending.
U.S. Sen. Elizabeth Warren of Massachusetts waves to supporters during a rally at Central Gwinnett High School, becoming the first Democrat to hold a campaign event in Georgia this year after launching a presidential bid. Gwinnett Democrats are touting the county, with its diverse population, as the future of the party and a destination for its presidential candidates. HYOSUB SHIN / HSHIN@AJC.COM
Photo: The Atlanta Journal-Constitution
Can Republicans make up lost ground in the suburbs?
The GOP held onto all of Georgia's major statewide offices in last year's midterms, but the party's poor performance in the rapidly diversifying Atlanta suburbs has prompted some soul searching for officials looking ahead to the 2020 races. The party is unquestionably tied to President Donald Trump, but Republican leadership in the Legislature is pledging to tackle economic policies rather than divisive social debates like abortion or "religious liberty" to keep suburbanites in the fold. Another area to watch could be infrastructure. Georgia has traditionally invested little in public transportation, but outgoing Gov. Nathan Deal supported many transit initiatives and 2018 was a watershed year for metro Atlanta transit. Kemp has pledged to continue "investment in targeted projects" such as bus rapid transit interchanges along Ga. 400 in north Fulton County, but he wants private as well as public investment.
Answer: Not sure yet, but off-year municipal elections offered more evidence of eroding GOP support in the burbs. Democratic-backed candidates won a string of metro Atlanta mayoral races, and flipped Savannah City Hall four years after a GOP "sea change" election. The Democratic suburban gains have also started to seep into Republican strategy, from a push for Medicaid waivers to Gov. Brian Kemp's selection of Kelly Loeffler to the U.S. Senate.
Gov. Brian Kemp speaks during a press conference to announce a proposed limited expansion of Medicaid in Georgia on November 4. (Alyssa Pointer/Atlanta Journal-Constitution)
How will Georgia adapt to a new healthcare landscape?
The state's Republican leaders have long rejected Obamacare's offer to expand Medicaid, but a growing number of GOP lawmakers want Georgia to apply for a waiver that would let the state insure more people under Medicaid. The move, depending on how it's designed, could insure thousands or hundreds of thousands of residents in a state with one of the country's highest uninsured rates. But a federal judge's recent decision striking down the entirety of Obamacare – a case Georgia had helped prosecute – has generated significant doses of uncertainty about what's to come for the state's health care system. The lawsuit, which is still making its way through the appeals process, could impact more than the half-million Georgians who have an insurance plan through the health care exchange. One more piece of the puzzle to watch: Brian Kemp tapped Tom Price – Donald Trump's former health secretary – to help craft his healthcare policy for his transition team.
Answer: Shortly after taking office, Gov. Brian Kemp won legislative approval to pursue federal healthcare "waivers" to stabilize insurance premiums and enroll tens of thousands of residents in Medicaid without expanding the program under the Affordable Care Act. Whether his plan will win federal approval is an open question. His administration expressed confidence that the feds will sign off on the plan, but as the year ended, there were rumblings that his choice of Kelly Loeffler for an open U.S. Senate seat over President Donald Trump's preferred pick could have repercussions.
MARTA hasn't raised fares in eight years. That could change next year.
Will voters welcome more MARTA?
If 2018 set the stage for mass expansion for mass transit in metro Atlanta, 2019 could be the overhauled system's make-or-break year. The Georgia Legislature passed a measure last year that lets voters in 13 metro Atlanta counties approve new sales taxes for transit construction and operations. And several counties are already off to the races - including Cobb, DeKalb, Fulton and Gwinnett. Transit advocates are closely watching a March referendum in Gwinnett, where voters could give the go-ahead for a MARTA rail extension to Jimmy Carter Boulevard and bus rapid transit routes on several major routes. If it passes – and it's no sure thing – it could pave the way for Cobb to follow suit. If it fails, transit expansion in metro Atlanta could hit the skids.
Answer: Yes and no. Gwinnett County voters rejected a MARTA transit expansion plan in a March referendum that likely would have passed had it been on the November 2018 ballot. But county officials have said they will bring a plan back to voters, perhaps as soon as 2020. And the transit service has pivoted to other types of rail for future waves of construction: A proposal for nearly 30 miles of light rail in Atlanta, 22 miles of heavier commuter rail in Clayton County. Other transit referendums could potentially more than double the size of the rail network over the next two decades.
Tensions were high at the Georgia state Capitol as lawmakers fought over a controversial bill that would ban most abortions at six weeks. Some Democrats stood up and walked out before the bill was introduced.
Photo: WSB-TV
How will Democrats leverage their new power in Georgia?
Georgia Democrats enter the year with some hard-earned clout after winning more than a dozen state legislative seats across the close-in suburbs of metro Atlanta, offsetting the defeats of three imperiled House Democrats in more rural territories. The party also carried the crown jewel of the 'burbs: The 6th District seat that was home in 2017 to the most expensive U.S. House race in U.S. history. With Lucy McBath's congressional win and a slate of Democratic newcomers to the Legislature, the party has more power than it has at any time since Gov. Nathan Deal's election. Democrats can handily block constitutional amendments and defeat other GOP proposals by picking off a handful of Republican votes. The party can also put more heft behind its major policy initiatives – expect a slate of progressive measures that include gun control - though they're still unlikely to pass. The new Democratic muscle could also put pressure on Republicans to avoid culture-wars legislation that would turn off suburban voters. After sweeping DeKalb County, Democrats are eager to target the handful of Cobb, Fulton and Gwinnett seats that are still in GOP hands. Next up may be the fast-changing area around Savannah. But they'll face a tougher task in wooing rural voters, who overwhelmingly sided with the GOP in 2018.
Answer: As the curtain fell on a tumultuous legislative session, this much was clear: Georgia Republicans are more willing than they have been in years to engage in partisan battles over culture war issues that party leaders once eagerly tried to avoid. And Democrats were more aggressive in fighting them, stoking threats of boycotts, a walk-out on the House floor and promises of political payback. One Democratic lawmaker was even forcibly removed from the podium as she railed against anti-abortion legislation. In the halls of Congress, all five Democratic members of Georgia's House delegation, voted to impeach President Donald Trump – including U.S. Rep. Lucy McBath, the most politically vulnerable incumbent in the state.
Greg Bluestein is a political reporter who covers the governor's office and state politics for The Atlanta Journal-Constitution.


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SEAFDEC/AQDINSTITUTIONAL REPOSITORY
SEAFDEC/AQD Institutional Repository Home
03 SEAFDEC/AQD External Publications
Journal Articles, Conference Papers and Book Chapters by SEAFDEC Staff
Limnological notes on the finfish production problem of Laguna de Bay.
Global styles
Elsevier - Harvard
Santiago, Alejandro E.
Environmental problems have significantly affected fishery production and management in Laguna de Bay, the largest lake in the Philippines. Fishermen and fishpen operators are complaining about the slow growth of fish and low yields in the lake. In the 70's two croppings were possible in fishpens since it took only 3 to 4 months then rear milkfish from fingerlings to marketable size (Felix, 1976). But in the early 80's, stocked fingerlings attained a marketable size of about 200 g after 8 to 15 months (LLDA, 1983). In 1973 when the total fishpen area was only 5,000 ha, the annual harvest was 4 metric tons (MT)/ha. When fishpens covered 31,000 ha of the lake area in 1982, the annual yield dropped to 2 MT/ha (Centeno et al., 1987). Furthermore, the total open water catch of nearly 83,000 MT in the early 60's (Rabanal et al., 1964) was reduced to one-fourth in the 80's.
While the big drop in yield has been largely attributed to the proliferation and mismanagement of fishpens, over-exploitation of lake resources, and seasonal changes in the productivity of the lake (Centeno et al., 1987), the author attributes the present crisis basically to a lack of understanding o the basic ecological attributes of Laguna de Bay and their relation to fish growth and production. This paper is a brief commentary on the Limnological characteristics of Laguna de Bay tat are quite important in finfish production.
Santiago, A. E. (1988). Limnological notes on the finfish production problem of Laguna de Bay. Natural and Applied Science Bulletin, 40(2), 119-121.
Milkfish; Fishery production; Water resources; Limnology; Water quality; Philippines
Journal Articles [1100]
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Links — Apryl A. Alexander, Psy.D.
What do people do with their psychology degrees?
See this great article from the American Psychological Association (APA) here.
What is the difference between a PhD and a PsyD?
The American Psychological Association (APA) offers a comparison here.
What is forensic psychology/psychology and law?
Forensic psychology refers to professional practice by any psychologist working within any sub-discipline of psychology (e.g., clinical, developmental, social, cognitive) when applying the scientific, technical, or specialized knowledge of psychology to the law to assist in addressing legal, contractual, and administrative matters. Check out this great video provided by the American Psychology-Law Society (AP-LS; APA Division 41) here to learn more!
How do I become forensic psychologist?
See this great article by Dr. Karen Franklin here.


Exquisite gold leopard head braced with 8mm brown tiger eye beads.
As tiger eye emblems insight, confidence and balance, this bracelet delivers energy for apprehensive individuals. Dress to impress with this perfect piece for any outfit.


text:
Rob Paton
Data-Driven Chemistry
Catalyst Discovery and Design
Reaction Mechanism and Selectivity
Phosphorus-Mediated sp2-sp3 Couplings for Selective C–H Fluoroalkylation of Complex Azines
February 15, 2021 /in Mechanistic Studies, Reaction Mechanism and Selectivity /by Robert Paton
Zhang, X.; Nottingham, K. G.; Patel, C.; Alegre-Requena, J. V.; Levy, J. N.; Paton, R. S.; McNally, A. Nature 2021, 594, 217–222.
http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png 0 0 Robert Paton http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png Robert Paton2021-02-15 16:26:542021-12-13 23:33:37Phosphorus-Mediated sp2-sp3 Couplings for Selective C–H Fluoroalkylation of Complex Azines
Mechanistic Investigation of Rh (I)-Catalyzed Asymmetric Suzuki-Miyaura Coupling with Racemic Allyl Halides
February 14, 2021 /in Reaction Mechanism and Selectivity /by Academic Web Pages
van Dijk, L.; Ardkhean, R.; Sidera, M.; Karabiyikoglu, S.; Sari, O.; Claridge, T. D. W.; Paton, R. S.; Fletcher, S. P. Nat. Catal. 2021, 4, 284–292
http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png 0 0 Academic Web Pages http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png Academic Web Pages2021-02-14 00:00:002021-08-24 15:19:20Mechanistic Investigation of Rh (I)-Catalyzed Asymmetric Suzuki-Miyaura Coupling with Racemic Allyl Halides
January 1, 2021 /in Data Driven Chemistry, Reaction Mechanism and Selectivity /by Academic Web Pages
A Python program to compute quasi-harmonic thermochemical data and potential energy surface diagrams from frequency calculations at a given temperature/concentration, corrected for the effects of vibrational scaling-factors. All (electronic, translational, rotational and vibrational) partition functions are recomputed and can be correct to any temperature or concentration. The first public version of GoodVibes was released in 2016 and it has undergone several revisions since, during which time it has been used by many groups around the world. The program is described in the publication: GoodVibes: automated thermochemistry for heterogeneous computational chemistry data
http://patonlab.server323.com/wp-content/uploads/2021/02/goodvibes_icon.png 300 300 Academic Web Pages http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png Academic Web Pages2021-01-01 19:25:522021-02-15 21:27:56Goodvibes
Asymmetric Total Synthesis and Determination of the Absolute Configuration of (+)-Srilankenyne via Sequence-sensitive Halogenations Guided by Conformational Analysis
January 1, 2021 /in Reaction Mechanism and Selectivity /by Academic Web Pages
Jang, H.; Kwak, S. Y.; Lee, D.; Alegre-Requena, J. V.; Kim, H.; Paton, R. S.; Kim, D. Org. Lett. 2021, 23, 1321–1326
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pyQRC
February 15, 2020 /in Reaction Mechanism and Selectivity /by Robert Paton
QRC is an abbreviation of Quick Reaction Coordinate. This provides a quick alternative to IRC (intrinsic reaction coordinate) calculations. The program will read a Gaussian frequency calculation and will create a new input file which has been projcted from the final coordinates along the Hessian eigenvector with a negative force constant. The magnitude of displacement can be adjusted on the command line. By default the projection will be in a positive sense (in relation to the imaginary normal mode) and the level of theory in the new input file will match that of the frequency calculation. A common application for pyQRC is in distorting ground state structures to remove annoying imaginary frequencies after reoptimization. This code has, in some form or other, been in use since around 2010.
http://patonlab.server323.com/wp-content/uploads/2021/02/pyQRC_icon.png 884 885 Robert Paton http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png Robert Paton2020-02-15 21:50:372021-02-15 22:11:22pyQRC
Unconventional Reactivity of Ethynylbenziodoxolone (EBX) Reagents and Thiols: Scope and Mechanism
Liu, B. Alegre-Requena, J. V.; Paton, R. S.; Miyake, G. Chem. Eur. J. 2020, 26, 2386–2394
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An Alkyne Linchpin Strategy for Drug: Pharmacophore Conjugation: Experimental and Computational Realization of a meta-Selective Inverse Sonogashira Coupling
Porey, S.; Zhang, X.; Bhowmick, S.; Singh, V. K.; Guin, S.; Paton, R. S.; Maiti, D. J. Am. Chem. Soc. 2020, 142, 3762–3774
http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png 0 0 Academic Web Pages http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png Academic Web Pages2020-01-01 00:00:002021-02-11 14:29:22An Alkyne Linchpin Strategy for Drug: Pharmacophore Conjugation: Experimental and Computational Realization of a meta-Selective Inverse Sonogashira Coupling
Cofactor-independent pinacolase directs non-Diels-Alderase biogenesis of the Brevianamides
Ye, Y.; Du, L.; Zhang, X.; Newmister, S. A.; McCauley, M.; Alegre-Requena, J. V.; Zhang W.; Mu, S.; Minami, A.; Fraley, A. E.; Adrover-Castellano, M. L.; Carney, N.; Shende, V. K.; Oikawa, H.; Kato H.; Tsukamoto, S.; Paton, R. S.; Williams R. M.; , Sherman, D. H.; Li, S. Nat. Catal. 2020, 3, 497–506
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Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins
Hintzen, J. C. J.; Poater, J.; Kumar, K.; Al Temimi, A. H. K.; Pieters, B. J. G. E.; Paton, R. S.; Bickelhaupt, F. M.; Mecinović, J. Molecules 2020, 25, 1918
http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png 0 0 Academic Web Pages http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png Academic Web Pages2020-01-01 00:00:002021-02-11 14:29:22Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins
Mechanism of biomolecular recognition of trimethyllysine by the fluorinated aromatic cage of KDM5A PHD3 finger
Pieters, B. J. G. E., Wuts, M. H. M., Poater, J.; Kumar, K.; White, P. B.; Kamps, J. J. A. G.; Sherman, W; Pruijn, G. J. M.; Paton, R. S.; Beuming, T.; Bickelhaupt, F. M.; Mecinović, J. Commun. Chem. 2020, 3, 69
http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png 0 0 Academic Web Pages http://patonlab.server323.com/wp-content/uploads/2021/02/clear.png Academic Web Pages2020-01-01 00:00:002021-02-11 14:29:22Mechanism of biomolecular recognition of trimethyllysine by the fluorinated aromatic cage of KDM5A PHD3 finger
Asymmetric Catalysis biosynthesis C-H functionalization catalysis catalytic mechanism conformational analysis data-mining Design DFT-D3 Dispersion Correction dynamics enantioselecitivty enantioselectivity enzyme catalysis featurization Gaussian GNN graph network H-bonding heterocycles Informatics ion-pairing Kinetic Isotope Effect kinetics machine learning mechanism molecular features natural products nmr non-covalent interactions Noncovalent Interactions oniom ions photocatalysis photochemistry prediction python Quasiharmonic regioselectivity site-selecitivity site-selectivity software stereoselectivity structure prediction thermochemistry Vibrational Entropy
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Just outside of the town centre is a large shopping area consisting of some major retailers in large retail units designed for ease of use to the modern day car commuter .
Portrack Lane was a cricket ground in Stockton-on-Tees, Durham. The first recorded match on the ground was in 1839, when Stockton played an All-England Eleven. The ground also hosted 2 first-class matches, the first of which was in 1858 when a combined Yorkshire and Durham team played Nottinghamshire. The second and final first-class match to be played on the ground came in 1861, when Yorkshire with Stockton-on-Tees played Cambridgeshire.
A second cut of 1,100 yards has been made across a loop in the River Tees. This canal has been made at Portrack near Stockton and stretches from Blue House Point to Newport. Portrack is situated on a hazardous meander on the Tees where large ships had to be tugged by men or horses towards the port of Stockton. This is called 'racking' and is the reason Port-rack acquired its name.


text:
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St. Stephen, "the Younger." Venerable Martyr suffered martyrdom with Three Hundred and Forty-Three other Christians, victims of the fury of the Iconoclast Emperor Constantine Copronymus A.D. 766. St. Irenarchus, and Seven Women, Martyrs, who suffered death with him A.D. 292.


Titan's PathwayTM Line Shaft conveyor is ideal for simple transportation of products or for integration into total computer directed systems, the "quick couple" drive system allows companies to easily reconfigure production lines to accommodate changes in plant layout. The basic design employs rollers which are independently driven by a urethane drive belt from a common drive shaft.
In addition to performing the standard functions of a conventional live roller conveyors it can easily be configured to solve a large variety of other special requirements, such as turning corners, lift, turn, rollover, transfer, upend, speed-up, slow down, brake, accumulate, sorting, providing dwell point work stations, 90 degree transfers, reversing, merging, diverting, from one central drive shaft. With most other types of conveyors, these extras would require special equipment, expensive design costs and multi drives.
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Between Frame Widths: 13", 16", 22", 28", 34", 40"


Dr. Malcolm Griffiths obtained his PhD in Physical Metallurgy from the University of Birmingham in 1981. After a three-year post-doctoral term working on radiation damage in Ti-alloys he joined AECL at the Chalk River Laboratories in 1984. He has worked on various aspects of materials performance in nuclear reactor cores during his 32 years with AECL. As manager of the Radiation Damage and Deformation Branch Malcolm was instrumental in developing strategies to support CANDU refurbishment that addressed improving pressure tube performance and the degradation of Inconel X-750 core components. Up until his retirement he was chair and project manager for the Candu Owners Group (COG) R&D program on pressure tube deformation and the COG joint project on Inconel X-750 spacer degradation.
From 2003-2013 Malcolm was on the editorial advisory board for the Journal of Nuclear Materials and was an editor from 2013-2016. In 2007 he was recipient of the 2005 Kroll medal from the American Society for Testing and Materials for his pioneering work on microstructure evolution in zirconium alloys during irradiation. He has published nearly 100 papers on material characterisation and reactor core materials performance. He is currently adjunct professor at Queens University, Department of Mechanical and Materials Engineering.
How did I get started in my career?
When my father died about 10 years ago I went back to England for the funeral. I was helping my brother to prepare my father's house for sale. Wading through the "maelstrom" of documents I came across some old files from when I was a physics student at Bristol University. There was an essay I had written when I was 20 years old about radiation damage in nuclear reactors. I had forgotten, but was reminded on seeing it that we had a choice from a list of about 50 topics on which to write essays as part of a course requirement in metal physics. Topics included wave-guides, superconductivity and other physically interesting phenomena. But, I was clearly fascinated by the effects of irradiation on materials. Looking back after 30 years I was amused to see that I had followed my dream and feel very fortunate to have had the opportunity to commit my working life, and now retirement, to the pursuit of the study of radiation effects on nuclear materials.
Through a series of fortunate events I started my career by studying electron damage in zirconium at Birmingham University. My supervisors were Mike Loretto and Ray Smallman, two legendary figures in the field of electron microscopy and physical metallurgy. I was an average student and after my PhD thesis defense (which I passed in 1981) I remember that Mike asked me why I looked so glum. I told him that I felt terrible because I realised how stupid I was. I told him that I felt small enough to exit the room by sliding under the door rather than walking through it. "Good," he said, "then we have been successful." "If you had left this place without the right amount of humility we would have failed." That was the start of my ongoing endeavour to learn and improve.
I joined Atomic Energy of Canada Limited in 1984 working in the Metallurgical Engineering Branch amongst engineers and scientists who were world-renowned in the field of zirconium metallurgy. I ended my career in 2016 as the manager of essentially the same branch, although the name had changed to "Radiation Damage and Deformation". When polling the staff for a name change I sent out a note with a list of suggested names to solicit feedback. I told them that my favourite was "Radiation Damage and DefamationJ"; striving for humility, for myself and my staff, was something important to me, although I had not realised it until then.
How did I get introduced to A.N.T. International?
AECL had been a subscriber to ZIRAT and LCC. I had sent staff to the ZIRAT courses and I had also gone to one or two seminars over the years. I found ZIRAT to be a refreshing break from immersion in the Canadian nuclear industry. It provided me with insight into the issues affecting nuclear reactors other than the CANDU. ZIRAT allowed me to see the LWR world through a different perspective, that of the CANDU scientist/engineer. I had given one or two guest lectures so I was familiar with the format and goals of the organisation. I was fortunate that Peter knew me and knew that I was a potential contributor in my retirement. I retired from AECL a little earlier than I had planned, partly because I was eager to start in a new role with ZIRAT, it felt right. There is a time in most people's career when one has gained a critical mass of knowledge and experience that allows one to make connections that others may not see, rather like being in the matrix. For me this is an exciting time and I am thrilled to have the opportunity, through A.N.T. International, to continue working in a field of work that I am passionate about.
When I was young I liked to play rugby and water-ski, but now I don't feel quite so robust. Now, I like to sail. I am fortunate to live in Deep River. I keep my sailboat in the marina, a short walk from my home, and can go sailing whenever I want. I also play drums and I am often working on some musical venture with various theatre groups in the Ottawa Valley (right now I am rehearsing for Mary Poppins), or preparing for a concert with the local community band. I like to bike along the numerous bush trails in the area and take walks with my Swedish-Canadian girlfriend. I am learning how to identify and pick mushrooms – so far, so good.


text:
Martin Hyatt
About Martin Hyatt
Martin Hyatt was born just outside of New Orleans. He attended Goddard College and Eugene Lang College of The New School. He holds an MFA in Creative Writing. He is the recipient of an Edward F. Albee Writing Fellowship and The New School Chapbook Award for fiction. His stories have been published in such places as Lodestar Quarterly, The Electric Literature Blog and Blithe House Quarterly. His award-winning debut novel, A Scarecrow's Bible, was published May 2006. It was named a Stonewall Honor Book by the American Library Association and won the Edmund White Award for Debut Fiction. In addition, it was nominated for the Ferro-Grumley Award, a Lambda Literary Award, and the Violet Quill Award. He was recently named a "Star of Tomorrow" in a Literary Idol feature in NY Magazine His new novel, Beautiful Gravity, was published in October, 2016. For his second novel, he also received a Stonewall Honor Book Award from the ALA. He is currently completing a memoir entitled Greyhound Boy, 1976. He has taught writing at such places at Hofstra, Parsons, and St. Francis College. He currently teaches Creative Writing at Southern New Hampshire University and Humanities at Devry NY and ASA College.
BEAUTIFUL GRAVITY
A SCARECROW'S BIBLE
READINGS AND EVENTS
Copyright © Martin Hyatt. All rights reserved.


August 1th, 2016, Scotland, UK – Luminis registered their seminal Cloud platform, the "Cloud RTI", on the UK Government's G-Cloud Digital Marketplace. Government Cloud (G-Cloud) is a UK government initiative to ease procurement of cloud services by government departments and to promote government-wide adoption of cloud computing. Luminis UK proactively encourages departments and authorities across the United Kingdom to use more Open Source technology in the Cloud. The Cloud RTI consists of a Cloud platform with a host of supporting tools that have been designed to help organisations in making the transition to Cloud computing, while benefiting from the advantages and insights of the Open Source community. The Luminis Cloud RTI is infrastructure-agnostic and allows software to run on infrastructure from multiple providers including both Microsoft Azure and Amazon AWS.
The Luminis Cloud RTI incorporates the latest practices and insights in Cloud computing from the Open Source community; it is designed to help organisations to make the transition to Cloud computing whilst allowing them the maximum freedom of technology choices. As an example the Luminis Cloud RTI supports the ability to implement hybrid Cloud strategies, ranging from multiple public Cloud providers up to and including on-premise and private cloud (if required). In January 2016, the Dutch software technology company Luminis selected the United Kingdom to establish their first operation outside the Netherlands as part of their international ambitions, the United States is planned to follow at a later stage.
2) An online store – the "Digital Marketplace" (previously: "CloudStore") that allows public sector bodies to search for services that are covered by the G-Cloud frameworks.
The service began in 2012 and had several calls for contracts. By May 2013 there were over 700 suppliers, over 80% of which were small and medium enterprises. £18.2 million of sales were made by April 2013. With the adoption of Cloud First policy in UK, in late February 2014 the sales have continued to grow, reportedly hitting over £50M in February 2014. These are based on the procurement of some 1,200 providers and 13,000 services, including both cloud services and (professional) specialist services as of November 2013.


Adding different vegetables into the meat component of the meal is a good way of getting kids used to eating vegetables.
Heat stir-fry pan on medium-hot flame. Add mince, onion, celery and carrots. Stir-fry until meat changes colour and the onion is transparent.
Add peas, broccoli, garlic and tomato paste. Stir -fry until meat and vegetable mixture becomes quite dry. Add soy sauce, mix well.
Add hot water, cook for another 5 minutes.
Stir chopped spinach through, season to taste.
Transfer cooked mince into an oven-proof dish or 4 individual dishes. Preheat oven to 180 C.
Spread mashed kumera over the meat and vegetable mixture, sprinkle with salt and pepper and score it with a fork. Spread Parmesan cheese over the top.


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Africa Top 40
Morning Mayhem
Tar. TV
DJ Fresh contract terminated by the SABC
Written by Seth Smith on July 11, 2019
The South African Broadcasting Corporation (SABC) has announced that it has terminated the contract of DJ Fresh, whose real name is Thato Sikwane, with immediate effect on Tuesday 9 July 2019. This comes weeks after an incident on air where an inappropriate, poor choice of words slipped out of the Dj's mouth last month.
According to a statement released by the SABC spokesperson, Vuyo Mthembu said on Tuesday, "the termination follows unsuccessful engagements between SABC Radio Management and DJ Fresh, after his usage of offensive language on-air." The BCCSA (The Broadcasting Complaints Commission of South Africa) found the SABC guilty for breaching clause 6 of their code of conduct.
The SABC claim that Dj Fresh would not apologise according to a letter sent to them from his lawyers. Dj Fresh said that he would apologise after he apparently came to an agreement with the SABC.
Nada Wotshela, Group Executive: Radio said to the media on Tuesday: "The SABC continues to be committed to ensuring sound governance and internal controls irrespective of an employee's or freelancer's position. The SABC will communicate in due course who will take over Metro FM's breakfast show, and we are grateful to the team who have held the fort during this period."
According to the statement, the "SABC remains committed to enhancing the growth of its on-air personalities brands across all its platforms."
"This will be done in line with the SABC's policies and procedures, and it must be understood that when an Independent Contractor breaches a contract of engagement, the SABC will invoke the provisions of the same contract in line with consequence management."
The future remains unclear for the Dj but only time will tell. Dj Fresh is still one of South Africa's well acclaimed and talented Dj's.
Seth Smith
The Standard Bank Luju Food & Lifestyle Festival Sway The Night Away
Sat-B – "Love Controller"
DJ Vitoto – "Online" ft. Moonchild Sanelly
Cashtime gets ready to release full catalogue of music
Jux – Sumaku ft Vanessa Mdee
Morning Mayhem is a show like no other. Don't be fooled by the name though because the mayhem is actually organised. The show is targeted at the busy and always on the move listener who wants the bottom line of African news, sports and entertainment. The Morning Mayhem is best described as the radio version of twitter.
The Wavy Show
Kizosada – Repeat
African Top 40 – Repeat
Kendrick Lebron
Palesa Mokoena
Sliqe – "Kennel Room"
Congo rules out using additional trial vaccines to combat Ebola
Italy court says Eritrean in migrant case was victim of mistaken identity
www.transafricaradio.net
info@transafricaradio.net
52 Keyes Ave, Rosebank
TransAfrica Radio has been at the forefront of digital Radio on the African continent since 2000 and the TransAfrica Radio brand is a respected name within the community of opinion makers, early adopters of trends & technology and Influencers.
Transafrica Radio


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The Apple IIe Card is a hardware emulation board, also referred to as compatibility card, which allows compatible Macintosh computers to run software designed for the Apple II series of computers (with the exception of the IIGS). Released in March 1991 for use with the LC family, Apple targeted the card at its widely dominated educational market to ease the transition from Apple II-based classrooms, with thousands of entrenched educational software titles, to Macintosh-based classrooms.

Overview
Well into the 1990s, most schools still had a substantial investment in Apple II computers and software in their classrooms and labs. However, by that period Apple was looking to phase out the Apple II line, and so introduced the Apple IIe Card as a means to transition Apple II educators (and to a smaller degree, home and small business users) by migrating them over to the Macintosh. By adding the optional PDS card to low cost Macintosh computers, it provided backwards compatibility with the vast Apple II software library of over 10,000 titles. Software could even be run directly from an Apple II floppy diskette, the same way as with an Apple IIe (made possible via the card's cable-adapter that connected a standard Apple 5.25 drive). A similar "Apple IIGS Card" was planned for running 16-bit Apple IIGS software, but was canceled after being deemed too costly, therefore leaving no migration path for that segment of the Apple II line.

Apple asked the media to call the peripheral the "Apple IIe option board", as earlier "emulator" cards were not successful. The Apple IIe Card worked in the Macintosh LC series (I, II, III, III+, 475, 520, 550, 575), as well as the LC-slot compatible Color Classic. When running in Apple II emulation mode, certain Macintosh peripherals and hardware could be "borrowed" and used as Apple II devices. For example, the mouse, keyboard, internal speaker, clock, serial ports (printer, modem, networking), extra RAM (up to 1024 KB), internal 3.5 floppy drive and hard disk all functioned as Apple II devices. Furthermore, with the included Y-cable, Apple II specific peripherals could be used as well: The Apple 5.25, Apple UniDisk 3.5, and an Apple II joystick or paddles. The host Macintosh required special emulation software (a boot disk) launched from System 6.0.8 to 7.5.5 in order to activate the IIe Card.

Technical aspects
Like the Apple IIe itself, the Apple IIe Card uses an onboard 65C02 CPU. The CPU is software-configurable to run at the Apple IIe's native 1.0 MHz speed or at an accelerated 1.9 MHz. Video emulation (text and graphics) is handled through software using native Macintosh QuickDraw routines, which often results in operations being slower than a real Apple IIe except on higher-end machines. Any Macintosh that supports the card can be switched into 560×384 resolution for better compatibility with the IIe's 280×192 color High-Resolution graphics (essentially doubled in both directions on the Macintosh) and 560x192 monochrome double-high-rez/80 column text mode (doubled vertically), using the card's onboard 17.234mhz oscillator in place of the usual video clock thanks to the local bus nature of the PDS slot. This was particularly applicable to the Color Classic which is otherwise fixed at 512×384 resolution; the monitor scan rate remains the same, but horizontal pixel density (and total pixel clocks per scanline) is increased by 10% to fit the greater resolution in the same width.

The IIe card has 256K RAM; half is used to emulate the Apple IIe's standard 128K memory (reproducing its 64K main RAM plus the 64K bank-switched Extended 80-Column Text Card), and half stores the IIe's ROM. Macworld reported that because Apple IIGS engineers helped design the IIe Card, all copy-protected and other software except for "a few very esoteric games" are compatible. The host Macintosh emulates or provides native access to many of the expansion cards and peripherals one might install in a bare Apple IIe. These services provided to the IIe card makes the simultaneous running of the host's System 7 impossible. Hardware services include a 1.44 MB 3.5" SuperDrive, mouse, 1 MB RAM, 80-column text and graphical monochrome or color display, clock, numeric keypad, two hardware serial ports (in addition to the emulated serial necessary for the IIe mouse), SCSI hard drive, and AppleShare file server. An included "Y-cable" enables the attachment of up to two external 140 KB floppy disk 5.25" Drives, an 800 KB "intelligent" 3.5" UniDisk drive, and a joystick or paddle control for use with the Apple IIe emulator. 800 KB 3.5" Drive and 1.44 MB SuperDrives are not recognized when attached via the Y-cable due to the Disk Controller on the IIe card lacking support. (chip labeled U1A located in zone A1 of card – lower left as pictured above)

The product included the PDS card, Y-cable, owner's manual and two 3.5" floppy disks: the 'Apple IIe installer disk' and the 'Apple IIe card startup disk'. Version 2.2.2d1 is the final revision of the startup disk. Version 2.2.1 and a patch to reach 2.2.2d1 was originally available at Apple Support Area (this software now archived and moved off site, as is the case with the  original manual).

Reception
Apple claimed that the LC helped the company regain educational market share lost to inexpensive PC clones. , about half of the LCs sold to schools used the IIe Card.

Technical specifications
 LSI Logic Gemini chip (similar to Mega II); a nearly complete Apple IIe on a single microcircuit – minus RAM, firmware, CPU and video generation
 IWM (Integrated Woz Machine) for floppy control functions
 256 KB RAM built-in (128 KB for Apple II memory, 128 KB reserved for Macintosh)
 65C02 processor running at either 1.023 MHz or 1.9 MHz
 High-density 26-pin connector with "Y-cable" supports joystick/paddles and two Apple 5.25" or UniDisk 3.5" floppy disk drives
 Ability to access up to 1 MB of native Macintosh RAM
 All Apple IIe text and video modes supported, via QuickDraw software emulation

Notes: When emulating the Apple IIe, only a full-screen mode is available and all native Macintosh functions are suspended while running (a proprietary graphical control panel, running outside MacOS, is available for configuring the virtual Apple II slots and peripherals; however, both native and emulated computer function are suspended during this activity). Macintosh functions and control resume only once emulation is completely shut down and exited.

Host system compatibility
The card plugs into the PDS slot in many of the LC-series Macintoshes, but not all models and system software combinations are supported. Apple's Tech Info Library article #8458 lists the following models as Apple IIe Card-compatible: Color Classic, Colour Classic II, LC, LC II, III & III+; LC 475, 520, 550, 575; Quadra 605 and Performa 4XX, 52X, 55X, 56X, and 57X. However, other 68K models that have an LC-compatible PDS slot and support 24-bit memory addressing are generally compatible with the Apple IIe Card but are not officially supported. The host Macintosh requires Apple's emulation software (a boot disk) launched from System 6.0.8 to 7.5.5 in order to activate the IIe Card. Systems 7.0 through 7.5.5 support both 24- and 32-bit addressing on suitable Macintosh models (from System 7.6 onwards, Macintosh system software does not support the required 24-bit addressing). 24-bit addressing can be enabled on supported systems with the Macintosh Memory control panel. The Apple IIe Card will not work with 32-bit addressing enabled or Macintosh System Software or machines locked to this mode.

Contrary to some sources, the LC 630 and Quadra 630 are not compatible with the Apple IIe card because those computers do not support 24-bit mode.

Timelines

See also
Apple II peripheral cards

References

External links
 Apple IIe Card FAQ
 Using an Apple IIe Card in Your Macintosh
 Macintosh Compatibility Table
 Comm Slot Compatibility
 Apple IIe Card software

IIe card
Compatibility cards
IIe card
Macintosh internals
Products introduced in 1991


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Q: how can i attach image to uiactivityviewcontroller message ios? How can attach an image to UIActivityViewController message type. If it is not possible by programatically, then tell me how to copy and paste image to pasteboard. here is my code.
UIImage *image = photoView.image;
UIPasteboard *pasteboard = [UIPasteboard generalPasteboard];
pasteboard.persistent = YES;
pasteboard.image = photoView.image;

NSString *firstN = [NSString stringWithFormat:@"First Name    : %@",((data.firstName)?data.firstName:@"")];
NSString *lastN = [NSString stringWithFormat:@"Last Name    : %@",((data.lastName)?data.lastName:@"")];
NSString *phoneMob = [NSString stringWithFormat:@"Mobile           : %@",((data.phoneMob)?data.phoneMob:@"")];
NSString *phoneHome = [NSString stringWithFormat:@"Home            : %@",((data.phoneHome)?data.phoneHome:@"")];
NSString *emailOff = [NSString stringWithFormat:@"Email(Off.)     : %@",((data.emailOffice)?data.emailOffice:@"")];
NSString *emailPers = [NSString stringWithFormat:@"Email(Pers.)  : %@",((data.emailPersonal)?data.emailPersonal:@"")];

NSArray *actItems = [NSArray arrayWithObjects:image,pasteboard,firstN,lastN,phoneMob,phoneHome,emailOff,emailPers, nil];

UIActivityViewController *actCtrl = [[UIActivityViewController alloc]initWithActivityItems:actItems applicationActivities:nil];

actCtrl.excludedActivityTypes = @[UIActivityTypePrint,UIActivityTypeCopyToPasteboard, UIActivityTypeAssignToContact,UIActivityTypeSaveToCameraRoll];

[self presentViewController:actCtrl animated:YES completion:nil ];

In the above code, i couldn't paste the image to the message body

A: You can't able to directly upload the image. You have to convert image to data and upload the data.


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Q: CCk fields to be grouped with add another item I created a new content type in Drupal 6 and added fields using CCK fields like country, state and zip code. I created a group named address so that it looks like:
Address
--- Country
--- State
--- Zip
Now I want a add new item below the label "Address" so that another address can be added. Please help me. Is there any module to do this?.. It should also have remove option
EG:
Address
Country
State
Zip

Address
Country
State
Zip

+Add another Address -Remove Address
Sorry for my poor english

A: If you don't want to use the CCK Address or Location modules, you can accomplish this using the 3.x branch of CCK. This branch has a module called Multigroup, which allows you to group fields together, and then get the add another functionality on the entire group.

A: There are modules that will create the fields for you and integrate with CCK. I would recommend looking at the Location module or the Addresses module.
I have not used the Addresses module, but I know that the Location module will do exactly what you want.  You can choose which parts of the address to show and allow adding/removing extra addresses.


text:
<component name="libraryTable">
  <library name="SBT: org.asynchttpclient:async-http-client-netty-utils:2.0.24:jar">
    <CLASSES>
      <root url="jar://$USER_HOME$/.ivy2/cache/org.asynchttpclient/async-http-client-netty-utils/jars/async-http-client-netty-utils-2.0.24.jar!/" />
    </CLASSES>
    <JAVADOC />
    <SOURCES>
      <root url="jar://$USER_HOME$/.ivy2/cache/org.asynchttpclient/async-http-client-netty-utils/srcs/async-http-client-netty-utils-2.0.24-sources.jar!/" />
    </SOURCES>
  </library>
</component>


text:
JAMA Internal Medicine
Subscribe to the JAMA Internal Medicine journal
Extranodal Lymphosarcoma of the Left Liver Lobe With Paraproteinemia
Samih Y. Alami, MD, PhD; Russel O. Bowman, PhD; Merrick H. Reese, MD; et al George J. Race, MD
From the departments of pathology (Drs. Alami; Bowman; and Race) and medicine (Dr. Reese), Baylor University Medical Center, Dallas. Dr. Alami is now with the Department of Clinical Pathology, American University Hospital, Beirut, Lebanon.
Arch Intern Med. 1969;123(1):64-68. doi:10.1001/archinte.1969.00300110066013
The association of gammapathies with lymphomas and related disorders has been increasingly reported.1-9 Cases of extranodal lymphosarcoma are relatively rare, and those originating in the liver, with associated serum M-components, are accordingly more rare. To the best of our knowledge, this latter association has not been reported by others.
The present report is concerned with a case of malignant lymphoma, lymphocytic type, associated with macroglobulinemia and increased IgG, which was recognized during a diagnostic work-up for anemia and an epigastric mass. Light chain typing of the IgM revealed the presence of type L specificity which is less commonly encountered.
Patient Summary The patient (BUMC 160-342), an 80-year-old white male, retired grocer, was admitted to Baylor University Medical Center on Aug 13, 1967. The patient had been in unusually good health and active, considering his age, until six to eight weeks prior to admission. He began to note the onset
Alami SY, Bowman RO, Reese MH, Race GJ. Extranodal Lymphosarcoma of the Left Liver Lobe With Paraproteinemia. Arch Intern Med. 1969;123(1):64–68. doi:10.1001/archinte.1969.00300110066013
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