Our friends over at Modiphius just shot us the following press release for their newest co-branded/published project on Kickstarter. This project funded in one day! If you've ever gotten anything from Modiphius, you know they publish or co-publish only top-notch stuff. This 5th edition adventure looks like it will be amazing with its historical inspirations. If you're inclined, have a read and check it out. Kickstarter links are below.
Odyssey of the Dragonlords is infused with inspiration from Greek epic. Your characters can make oaths which they must swear by, much like the oaths that were sworn by the Greek lords to the great King Menelaus which resulted in the Trojan War as told in the Iliad by Homer. Should these oaths be broken your characters can suffer a visit from the Erinyes, furies who uphold the law of the gods. The concepts of 'Xenia' (Guest Friendship) and 'Kleos' (Glory) are also important factors for your characters to consider within the epic Greek myth inspired world of Thylea. The word 'epic' is being used in its literal and original sense to refer to specific qualities about Odyssey of the Dragonlords.
BRONZE MEDALIST – Pledge US $25 or more.
This tier includes the PDF campaign book and digital versions of all stretch goals.
This tier includes the hardcover version of Odyssey of the Dragonlords, the softcover player's guide, and digital versions of all stretch goals.


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NewsAll Bengals+
Bengals pivot from draft, eye undrafted free agents
Get the latest on the Bengals' undrafted free agent signings
James Rapien
It's been a busy few days for Zac Taylor and the Bengals. They selected a franchise quarterback in Joe Burrow, followed it up by drafting Clemson wide receiver Tee Higgins, before adding three linebackers and two lineman in the NFL Draft.
"We did feel like we wanted to get some linebackers that we could add to (the mix). That's why we did so much work on them," Taylor said. "We identified areas that we wanted to hit and we felt like the right players were there, so we didn't overdraft a position that we went into the draft targeting. Again, we feel very good about how it all ended up."
The Bengals will continue to add to their team on Saturday night and Sunday. All 32 NFL teams will sign undrafted free agents. Cincinnati had 17 available roster spots following the draft.
This tracker will be updated with the latest signings. Here's the latest:
The Bengals' reportedly agreed to terms with multiple undrafted free agents on Sunday, including Georgia defensive lineman Tyler Clark.
Clark had 119 tackles and 6.5 sacks in four seasons with the Bulldogs. He's 6-4. 300 pounds and was a four-year starter. He earned second-team All-SEC honors as a senior, finishing with 26 tackles (eight for loss) and 2.5 sacks in 13 games.
Cincinnati also added Kansas State defensive tackle Trey Dishon. He had 93 career tackles (15.5 for loss) and eight sacks for the Wildcats.
The Bengals also signed USF tight end Mitchell Wilcox according to Aaron Wilson. Wilcox was a first-team All-American Athletic Conference selection in 2018. He finished 43 receptions and 540 receiving yards, which were both school records. He had 28 receptions for 350 yards last season. The 6-3, 247 pound tight end is a willing blocker, which is probably his key to sticking at the next level. Wilcox is a nice signing that multiple NFL teams were likely interested in. He's a realistic candidate for the practice squad.
The Bengals are signing Oregon State offensive tackle Clay Cordasco. He made the announcement on early Sunday morning. Cordasco was a junior college transfer that appeared in 21 games in two seasons for the Beavers. The 6-5, 314-pound offensive lineman made 12 starts last season.
Cordasco is versatile, much like Bengals sixth round selection Hakeem Adeniji. He played both guard and tackle in college and took practice snaps at center.
The Bengals are signing Arkansas running back Devway Whaley according to Danny West of 247 Sports.
Whaley ran for 1,807 yards, scored 17 touchdowns and had 423 receiving yards in four seasons at Arkansas.
Whaley was an Under Armour All-American coming out of high school. He ran for 602 yards as a freshman, but dealt with injuries and never exceeded that total.
The Bengals are signing East Carolina outside linebacker Kendall Futrell according to NFL Network's Tom Pelissero.
Futrell finished with 63 tackles (16 for loss), 11 sacks and forced three fumbles in 12 games last season.
The Bengals are also signing Dartmouth cornerback Isiah Swann according to Pelissero.
Swann is Dartmouth's all-time leader in interceptions with 17. He returned four of them for touchdowns.
He ran a 4.40 40-yard dash during his virtual pro day and had a 39" vertical jump. The Bengals didn't draft a cornerback, but Swann has the athleticism, size and production they're looking for. He's listed at 6-0, 195 pounds.
The Bengals signed guard Josh Knipfel from Iowa State according to the school.
Knipfel made 39 straight starts for the Cyclones at right guard. He was an Honorable Mention All-Big 12 selection in each of the past two seasons.
Iowa State also announced that linebacker Marcel Spears Jr. has agreed to terms with the Bengals.
He was AP Second-Team All Big-12 as a senior. Spears made 39 consecutive starts and led the team with 92 tackles last season. He finished with four interceptions, two 'pick-sixes' and two forced fumbles in 2019.
Wake Forest wide receiver Scotty Washington signed with the Bengals according to the school.
Reynolds averaged 17.3 yards per catch last season. He's 6-5, 225 pounds and scored 13 career touchdowns.
Lions Head Coach Dan Campbell Delivers Press Conference For the Ages
By AllBengals Staff
Hue Jackson Interviews with Bengals' AFC North Rival
Four Bengals Uniform Redesigns Worth Checking Out
Watch: Bengals to Get New Uniforms in 2021
Odds on Eric Bieniemy, Joe Brady and Others Potentially Landing in Houston
By James Rapien
Bengals WR John Ross Visits Andy Dalton in Texas
Betting Odds on Deshaun Watson's Next Team Are Here
GM Report
Joe Burrow Chimes in on the Bengals' Offensive Line

redpajama_set_name: RedPajamaCommonCrawl


1.carbon nanotubeandnanofiltrationof Shenzhen Topology Precision Film Technology Co., Ltd.is favored by the majority of customers love, We have established long-term cooperation with many partner, Nanofabricationx318b677n,anodic aluminum oxidefrom Topological fine filmmeet the needs of our customers. Topological fine filmstrength,abide by contract, keep faith, take quality and credit of contract,obtained the customer trust and praise.
2.Shenzhen Topology Precision Film Technology Co., Ltd. has been devoted to study the needs of Topological fine film industrial customers, ant tailored to customers demand and solutions. The advantage of Topological fine film lies not only in the industry-leading technology and the elite professional team, but also to provide excellent services in Double-pass AAO nano-template,Ultra-thin porous nano-template,Aluminum based AAO template,and the enthusiasm of positive innovation and faith of respect promise . Become a customer trusted Nanofabrication low price in the marke integrated service providers, to help customers realize the business value of Nano, is Topological fine film unswerving mission and pursuit. Details: 4.As a one-dimensional nanomaterial, carbon nanotube is light in weight, hexagonal structure is perfectly connected, and has many abnormal mechanical, electrical and chemical properties. In recent years, with the deepening of research on carbon nanotubes and nanomaterials, its broad application prospects are constantly being revealed.Carbon nanotube, also known as bucky tube, is a one-dimensional quantum material with a special structure (radial size is nanometer-scale, axial dimension is on the order of micrometers, and both ends of the tube are substantially sealed). The carbon nanotube is mainly composed of a plurality of coaxial tubes of a plurality of layers of carbon atoms arranged in a hexagonal shape. The layer maintains a fixed distance between the layers, about 0.34 nm, and the diameter is generally 2-20 nm. And according to the different orientation of the carbon hexagon in the axial direction, it can be divided into three types: zigzag, armchair and spiral. Among them, the spiral type carbon nanotube has chirality, and the zigzag and armchair type carbon nanotubes have no chirality.On October 27, 2017, the World Health Organizations International Agency for Research on Cancer published a preliminary list of carcinogens, carbon nanotubes, multi-walled MWCNT-7 in the list of Class 2B carcinogens.


The answer is now YES! Since recently achieving the WRAS Material Approval for the EPDM compound used in the Val-Matic 'Swing-Flex'® Resilient Hinge Check Valve, there is now the option for producing an eccentric plug valve with BS 6920 compliant wetted parts.
The Val-Matic 'Cam-Centric'® eccentric plug valve meets WIMES 8.09 with BS 5158 approval and has dedicated shaft seals in the form of the Val-Matic Grit-Guards™.
The flow characteristic of the Val-Matic plug valve with rectangular port makes it ideal for consistently reliable and accurate proportional control of fluids with a reduced potential for cavitation in comparison with a typical Butterfly Valve. The ¼ turn eccentric nature of the shaft and plug design ensures no contact with the valve seat during modulating operation so the torques and wear are minimal providing extensive trouble free performance and whole life cost savings.
To learn more about the Val-Matic Plug Valves WATCH this video with MGA Controls Technical expert, Jason Dean.


Received a e-mail from the CRE recruiter today. I called and was told that they were having trouble verifying my employment information because no one would respond to their requests for info. I verified the employer information they had and she said they would keep trying.
So much work just to find a job in an industry that needs people!


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Are Fizzers Gluten Free?
Are Fizzers Gluten-Free?
All About Fizzers
Fizzers Ingredients
Fizzers Nutritional Information
Fizzers are gluten-free. If you enjoy this classic candy but are on a gluten-free diet, you're in luck. There are no ingredients used in the making of Fizzers that contain gluten. This candy is labelled as Coeliac and Celiac friendly. Fizzers are also free of gelatine and vegan friendly.
Fizzers are a popular candy by the brand Swizzels. Almost every Halloween, trick-or-treaters will find a roll or two in their candy stash. This candy comes in a roll of small circular pieces that are in the shape of a tiny puck. While the candy is hard at first touch, it becomes chewy once it's placed in your mouth. The candy begins to fizz as you chew on it.
Many people will place their Fizzers in soda and watch them dissolve. This popular candy has different names around the world as well, known as Smarties in the US and Rockets in Canada. Fizzers were the first invention behind the Swizzels brand from the UK and date back as early as 1933. Each roll of Fizzers comes with 6 fruity flavors:
While many people are used to seeing the rolls of Fizzers available around Halloween, people who really love this treat are able to buy it in bags or even giant Fizzer rolls.
Swizzels is a UK-based confectionery company that exports candy to more than 20 countries. This brand is worth over 47 million pounds, with Halloween making up for the majority of the company's sales. While they began the candy journey selling Fizzers, they now have an assortment of lollies, mints, chocolate, and more.
Each flavor of Fizzers comes in a different color. These candies appear as tiny pastel puck shapes, however, no artificial colors are used to create these sweets. The flavor of Fizzers can be described as sweet and tangy, which means you can expect a higher sugar content in each roll.
These are the ingredients used to make Fizzers. (Please note, all ingredients used in Fizzers are gluten-free and Halal)
Acidity regulator
Copper Chlorophyllin
Nutritional value For 100 grams of Fizzers (1 regular sized roll)
Energy (KJ) 1165
Energy (KCAL) 392
Fat 3.1 grams
Saturated fat 3.1 grams
Carbohydrates 87.6 grams
Sugars 85.6 grams
Protein 0.01 grams
Salt 2.1 grams
If you're looking for a gluten-free candy to hand out at Halloween or put on the treat table for parties, Fizzers are an excellent choice. However, each package of Fizzers contains a high amount of sugar. It is not recommended to eat more than one serving of Fizzers in a day or you may consume too much sugar.
Fizzers do not contain any vitamins, antioxidants, or other ingredients that are needed for a well-balanced diet. Nutrition-wise, you should not eat Fizzers each day, but once in a while will not cause any harm.
https://www.aquarterof.co.uk/fizzers
https://swizzels.com/nutritional-information/pick-n-mix-fizzers/
https://en.wikipedia.org/wiki/Swizzels
https://swizzels.com/sweets/fizzers/
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About Ashley Dolan
As someone who is gluten-free and has other dietary restrictions, I made this site as a resource to answer common questions.
Est. in 2006 - Learn more about us.
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Stride Gaming (LON:STR) share price jumps after putting itself up for sale | City A.M.
Leading online bingo operator Stride Gaming's share price jumped eight per cent in morning trading after confirming reports that it is weighing up a potential sale of the company.
The gambling firm, which owns brands such as Kitty Bingo and Lucky Pants Bingo, said today that it was mulling a sale as one strategic option, although it added that it was not considering any current proposals.
Stride Gaming's share price jumped more than eight per cent to 111p this morning.
The news, first reported in The Times, comes in the wake of a £4m compliance fine slapped on the firm in September.
Listed on London's Alternative Investment Market (Aim), Stride Gaming has seen the value of its share price more than halve in the last 12 months.
Its board also said today that it is also reviewing a "more aggressive" UK and international strategy, as well as expanding operations through acquisitions in the UK and/or international markets.
It expects to provide more detail of the review before announcing its interim results for the period ending 28 February 2019.


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Change Is Now Underway At University Mall In Nacogdoches [PHOTOS]
If you've kept up with this page at all, then there's a good chance that you've seen stories about the University Mall in Nacogdoches. The most recent one was one I wrote about more stores closing in the mall back in February. If you don't remember it, you can check out the story and photos by clicking the link below:
More Stores Closing: What's Next For University Mall
However, when I drove by today, I noticed some changes that were taking place at the mall. I actually went back so that I could get a couple of pictures. This is what I saw:
That's the full photo that was taken. Here's a closer view:
Now, if you're familiar with the mall, then you already know that where that big, gaping hole is located is where Hibbett Sports used to be. Not anymore, obviously.
So, what's really going on at the mall?
We've heard rumors around town that it's going to be a more of a shopping center, rather than a traditional mall. That would mean that there would not be a hallway, and - even though the stores would be connected by walls - the stores would be more "standalone". But again, that's just a rumor that's circulating around.
What are your thoughts on all this? Do you know what's going on at the mall? Or, would you care to speculate? Feel free to drop either of those in the comment section below!
Filed Under: change, changes, mall, nacogdoches, photos, pictures, University Mall
Categories: East Texas News
Underrated Elton John: The Most Overlooked Song From Every Album
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Enterprise East Cambridgeshire | What qualification will I get?
There are four levels of apprenticeships, covering all skill levels. Each will give you a different qualification.
Intermediate Apprenticeships are the most popular level of apprenticeship and account for about 60% of all apprenticeships. They will give you what's known as a Level 2 qualification - usually an NVQ level 2 which is the equivalent of five good GCSE passes. You might sometimes also work towards a BTEC, GCSE, or City & Guilds qualification. This level of apprenticeship usually lasts around 12-18 months, although they can be longer or shorter. You can also choose to go on to do an Advanced Apprenticeship afterwards, to get even more qualifications.
Advanced Apprenticeships are the next level up - and will give you a Level 3 qualification, the equivalent of two A-level passes. You'll also gain relevant technical certificates or qualifications (depending on your type of apprenticeship). Usually Advanced Apprenticeships last around 24 months, although they can sometimes be longer or shorter.
If you are looking to obtain the equivalent of a higher education certificate, higher education diploma or a foundation degree then you should look at Higher Apprenticeships. Classed as Level 4, 5 and even 6, many of these last from 12 to 24 months, though some can even last as long as five years!
Degree apprenticeships are quite new, they have only been around since 2015. These are classed as Level 6 and 7 and typically last for 4 years, though there is no maximum timeframe. By the end of this apprenticeship you'll have earned your full Master's or Bachelor's degree and, unlike university leavers, you will have been earning the entire time and have no student debts.


Having a recreational vehicle gives you so much freedom to explore the world without leaving all those comforts and luxuries you are accustomed to in your home behind. Perhaps the only thing that can hamper that freedom is a limited supply of electricity. You might need to look for places with an electrical service to camp out.
A good option is to get yourself portable solar panels for RV. With these more sustainable sources of energy, you can take advantage of the sun's UV rays and convert that into energy in order to supply your home with the electricity you need to power up your appliances.
Thankfully, there is a cornucopia of portable solar panels for RV out there ideal for the use of people who want an alternative and eco-friendly sources of RV energy or those who want more stability and security in their energy source. Find out below which products we highly recommend.
1.1 Which One Should You Get?
2.0.1 1. Start small and build from there.
2.0.2 2. Consider whether you should go for flat or curved panels.
2.0.3 3. Make sure you get yourself a nice controller.
2.0.4 4. Make sure everything is compatible.
2.0.5 5. Choose those easier to use.
2.1 What to Do Next?
Aside from having more freedom to explore the world, what with a more sustainable source of energy, there are plenty of other reasons why you should get yourself solar panels for RV. First, it is a more cost-effective way to run your appliances. Sure, you can rely on your RV's batteries but that will run out quickly and you will need to hook up to an electrical service to replenish your RV's batteries. You can also get yourself a handy generator that runs on propane or gas, but a full tank will last you for 8-20 hours only depending on the fuel you are using. You will need to spend money to refill the generator tank.
A solar panel is still the cheapest option as solar energy is free. You just need to set it up in an area where it will receive a lot of sunlight.
Using solar energy is also better for the environment. It doesn't emit harmful gases or chemical fumes unlike fuels like gas. It is also a quieter choice. Generators can be noisy and using your RV's battery can also cause considerable vibrations and noise. A solar panel, on the other hand, doesn't have such a problem.
These are just some of the reasons why you should invest in a solar panel for your RV.
This is a good mid-priced portable and foldable solar panel for RVs. It folds down to a small size, great for RV and camping needs. It can provide up to 500-watt hours in a day or depending on the amount of sunlight your home is getting. It can be connected to different types of RV batteries such as flooded, gel, sealed and lithium.
It stands up easily, thanks to its heavy-duty stand. You can be assured that this solar panel will last for a long time, thanks to its corrosion-resistant properties. It is completely adjustable as well, making it easier for you to find the best spot for it while camping out.
This is completely compatible with mobile homes such as RVs, trailers and boats, thanks to its negative-ground charge control system. It eliminates the danger of experiencing electric shocks, thanks to its low voltage mechanisms.
You will find this highly reliable. It comes with 2 solar panels made from monocrystalline materials that is capable of supplying 50 watts of energy for each panel.
The materials used are also resistant to corrosion and has completely adjustable functions for easier transport and installation. If you want to add more panels, don't worry because this one can accommodate your needs with its expandable system.
It prevents the risks for overcharging as well, thanks to its solar charge controller that is built in the system.
It collects energy even during overcast or cloudy days. This system is also waterproof. Even the controller is resistant to bad weather conditions.
Many customers said it is not difficult to lift at all to your RV. Also, it comes with a casing made from neoprene that you can use to cover the panels up while configuring it.
Some said the LED lights on the panel aren't that bright.
A slightly more affordable suitcase-style portable and foldable solar panel for RVs, this one boasts of polycrystalline panels, which is a kind of material known for its efficiency. The stands are made from aluminum materials, boasting of durability so your panels can stay upright. It comes with an HQST 20A kind of controller that is separated by wires with a length of 10 feet, ensuring that you can connect it to your batteries with ease.
It is one of the easiest solar panels to use. It has a temperature sensor integrated in the system that ensures your batteries are charged accurately.
The controller is easy to use in your RV as well. It can be operated using 12V and 24V electrical systems and even comes with an LCD display where you can easily see the information you need to check. Its plug and play functionality makes this a cinch to use. Even those who are using solar panels for the first time will find it easy to use.
A lot of customers commented on how neatly packaged this is. It comes with a bag where you can easily slide the panels and out of.
The battery charge shows how many percentages of battery power it has left. The sides are also reinforced, ensuring durability.
Customers said the customer service of this product is good.
Some said they wished it came with instructions on the wiring harness.
Affordability meets quality is what this foldable solar panel can offer. It packs a punch when it comes to solar panel capability as well. With up to 100W of power, you can power up even your most power-hungry appliances. It is also a portable option because it is thin with only 0.2 inches of thickness and has 5.2 pounds of weight.
This product doesn't get easily damaged during transport, thanks to its fabric pocket. It also comes with a handle that you can use to lug it around with ease.
This solar panel has one of the best outputs. With its solar cell made from monocrystalline materials, you can be assured that you have a higher power output and efficiency. The design also eliminates hotspots and power loss due to mismatch.
It comes with a solar controller already. No need to buy it as an extra tool. The controller even comes with a 1-year warranty.
Its portability is also a good point. It is thinner and smaller than many standard solar panels, but it did not compromise on power output. A lot of customers also liked how lightweight it is.
The material comes with a 5-year warranty and the power output is backed by 25 years of warranty.
There is a customer who said it's not completely weatherproof.
This is the most expensive solar panel in this list, but it comes complete with everything you might need in solar connectivity. You have the solar panel propped up by a durable stand, MC4 cables, manual for easier installation and alligator clamp cables. These are the things you need to ensure that you charge to your RV's battery with ease.
The panels are made from monocrystalline cells, which is the best when it comes to utilizing sun power. It increases the efficiency of solar panels by as much as 25%.
This is easy to use as it has been designed with new solar panel users in mind. Both panels are high-efficiency panels that can provide your RV with the energy you need while living off-the-grid. Simply unfold it and put it in an area with plenty of sunlight.
It has a good amount of power as well. It can be used to power up smaller inverters, a/c fans and microwaves, to name a few.
It has everything you need already, which makes set-up a cinch.
It is lightweight as well, which makes this ideal to bring with you anywhere where you need an extra source of energy. It folds down to a small size as well.
It comes with a money back guarantee. If you are not satisfied with it, you can return it and get your money back.
The hefty price tag can be a big setback for some.
Go ahead and choose the Renogy 100 Watt 12 Volt Monocrystalline Foldable Portable Solar Suitcase if you are looking for something durable and loaded with safety features. It is a mid-priced solar panel though so if you are looking for the cheapest one, this isn't it. However, that compromise between price and functionality makes this a winning option for those looking for quality and affordability.
The HQST Polycrystalline Portable Foldable Solar Panel Suitcase is an easy product to use. Its plug and play functions make this easier to use in RVs. If you don't like a difficult set-up, this is a good choice for you.
If you are looking for something more compact, the Dokio 100 Watts 12 Volts Monocrystalline Foldable Solar Panel is the best choice for you. It is thinner and lighter, which is what makes this easier to use and bring to your camping trips.
Get the Acopower 120W Portable Solar Panel for something that is easier to set up. It's basically something that even those new to installing solar panels in their RV can use.
1. Start small and build from there.
Don't get too hasty and buy kits with plenty of panels. It is more ideal to start with a small kit, choosing one that has the option for expandability. This way, if you think you need more power, you can simply add more panels as needed.
2. Consider whether you should go for flat or curved panels.
Most portable solar panels are flat but there may also be those that have a slight curve to them. Curved panels are better as a fixed solar panel as they don't diminish your RV's aerodynamics. However, for something you can just unfold as you need it, flat ones would be a better option as they are more durable and less expensive.
3. Make sure you get yourself a nice controller.
Not all of the solar panel kits you are getting comes with a controller. Before buying, find out first if this is included in your purchase. Otherwise, you will have to shell out more money to get one.
4. Make sure everything is compatible.
RV-specific solar panels are the best because they have been designed specifically for RV connectivity. Most of them can be plugged in and ready to be used. No need for conversions or to use adapters. However, make sure you still go out of your way to check whether what you are buying is compatible with your RV.
5. Choose those easier to use.
It shouldn't be too difficult to install or use. Pick lightweight and portable solar panels that are RV-compatible, so they are easier to use.
Make sure you have everything you need in your RV, so you can ensure comfort while going off-the-grid. Aside from a portable solar panel, there might be other things you want to add to your RV such as power surge protector and appliances like an RV washer and dryer or air conditioning system. Head to our homepage to find out what products we recommend.


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ASX update; Magellan takes a swing
Drew Meredith
Mon 21 Sep 2020
ASX nears three month low, Magellan (ASX:MFG) takes a swing, US markets head lower
The selling pressure continued on Monday, the ASX 200 (ASX:XJO) falling another 0.7%, now nearing the low points of June.
The selling was widespread, National Australia Bank Ltd (ASX:NAB) and BHP Group Ltd (ASX:BHP) down 1.4% and 1.2% respectively.
The biggest news came from Magellan Financial Group (ASX:MFG), announcing a $140 million on balance sheet investment, in the latest Australian investment bank, Barrenjoey Capital Partners.
The investment has been made from MFGs balance sheet, not within one of its many equity funds; shares fell 3.4% on the news.
This decision is a difficult one to judge, a fund manager providing seed capital for an investment bank, where generally it's the other way around; I'll be reserving judgement for at least six months.
At the other end of the spectrum Platinum Asset Management Ltd (ASX:PTM) CEO Andrew Clifford has suggested there are signs of a "fully fledged investment mania" driving the incredible rally in stocks.
Gold miners as gold exposure, Virgin Money stalls, Harvey Norman recovery continues
OceanaGold Ltd (ASX:OGC) and St Barbara Mining Ltd (ASX:SBM) reiterated the very real difference between an exposure to gold bullion and an investment in gold miners.
Both fell around 7% on Monday after announcing unexpected production setbacks or worse than anticipated results.
I'm not suggesting that gold miners can't be quality investments, rather that for those seeking a hedge against volatility, physical bullion is the most suitable option.
Australian-listed UK 'challenge' bank Virgin Money UK (ASX:VUK) fell 9.2% after receiving a number of broker downgrades as the threat of UK-wide lockdowns increase along with an increasing likelihood of negative rates, which would further hit profit margins.
Harvey Norman Holdings Ltd (ASX:HVN) added 2.1% after providing a positive update to investors, global sales increasing 30.6% from July to September and Australian franchise sales recovering by a further 34%. The result was a 180% increase in profit across July and August.
The company is benefitting from a diversion of spending on travel, but its yet to be seen what impact the end of Job Keeper payments will have in March.
Tik Tok deal on again, off again, Dow falls 500 points, still waiting on stimulus
US markets were once again hit with a combination of rising geopolitical risk and a lack of clarity on fiscal stimulus.
After appearing to cool relations with China, the deal made by Oracle Inc. (NASDAQ:ORCL) and Walmart Inc. (NYSE:WMT) to acquire 20% of the US operations of Tik Tok appears dead after Trump threatened to renege on his approval. The Chinese are similarly pushing back on the threat to their own privacy.
Over the weekend a Federal Judge blocked Trump's ban on the WeChat app, suggesting it was an important communication tool for Chinese Americans, showing the checks and balances of the US system still have some power.
A second stimulus deal for a stuttering US economy facing the threat of another wave of lockdowns appears unlikely, hitting financials with JP Morgan Inc. (NYSE:JPM) heading 3.1% lower.
The banking sector was also hit by a investigative story highlighting many illicit transactions occurring through global banks.
Overall, the S&P 500 finished down 1.3%, but the technology sector, behind Adode (NASDAQ:ADBE) and Zoom Communications (NASDAQ:ZM) held the Nasdaq to a loss of just 0.1%.
This trend is set to continue as the world comes to terms with an impending election, stuttering growth and the threat of a second wave of lockdowns due to the resurgence of COVID.
Drew is one of the Founder's and Director's of The Inside Network and Wattle Partners. He is an experienced financial adviser, providing advice across the entire spectrum of finance and investing, with specific expertise in SMSF's, portfolio construction, direct shares and managed fund investing. GENERAL ADVICE WARNING: Any information published by Drew is limited to general financial advice only (under AFSL: 383 169). Please consult a trusted financial adviser before acting on the information.
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India All India 30 Dec 2019 'CAA is too little compassion, coming too late': Sadhguru
'CAA is too little compassion, coming too late': Sadhguru
Published : Dec 30, 2019, 1:17 pm IST
Updated : Dec 30, 2019, 1:17 pm IST
He said that 72 years ago a 'whole lot of people did not understand what this meant really.'
Sadhguru went on to say that the situation on the other side is 'different because by law there is discrimination against the minorities.' (Photo: ANI)
New Delhi: Supporting the Citizenship (Amendment) Act and National Register for Citizens (NRC), prominent spiritual leader Sadhguru Jaggi Vasudev said that it is "too little compassion, coming too late."
"In my opinion, CAA is too little compassion, coming too late. This Bill is only focused on religious persecution. Looking at the reactions on the street, the vehemence with which people are fighting, I was wondering did I miss something. Am I not getting something here," Sadhguru told a gathering while speaking on the CAA, NRC and the protests against them.
"This is a dangerous game people are playing. I think there is certain desperation among certain people, who misinformed illiterate masses of religious groups who went wild thinking that the local Indian Muslims will lose their citizenship. That's what they conveyed," he added.
He also said that such "mischief should not have worked on the scale that it worked."
"It's unfortunate. Still in today's day and age where you can just open up your phone and read the Act, what does it say. Any student can read it, but all of them are coming and behaving like illiterate people. They are studying in premier universities and how come they can't read the Act. It's really sad that such a thing can happen," he said.
Sadhguru further stated that in some way the government has "failed to communicate this properly."
"Otherwise, personally I don't see one issue on these things. But communication-wise, the way it is communicated unfortunately a certain number of people are perceiving it as a threat to them. That must definitely change," he said.
Talking about NRC, Sadhguru said that it is a normal procedure and every citizen in the country should be registered.
Talking about partition, Sadhguru stated, "The country, at least one part, not India, the other two parts that happened, happened on a religious basis. People divided the land on a religious basis. Fortunately, we chose to be a secular nation, but the others chose to be religious republics. But not everybody changed sides... Not everybody will leave their property, their life, their everything, and travel just because somebody drew a line."
"So, quite a substantial number of them stayed back. There is a lot of debate about percentages, I am not an expert on this either. They say 23 per cent stayed back in West Pakistan and nearly 30 per cent stayed back in East Pakistan. That's what people saying. Because nobody has perfect numbers I believe, but it is somewhere around that, it can't be totally wrong," he said.
"But then the 1971 war happened and East Pakistan became Bangladesh. Then, widespread persecution of the minorities happened. At that time, nearly 18-19 per cent of the people left and came back to the Indian side. They have got mixed up, there was no proper arrangement. They just got mixed up with the local population. Some of them are still in refugee camps, unfortunately," he added.
Sadhguru went on to say that the situation on the other side is "different because by law there is discrimination against the minorities."
"In the eyes of the law, all citizens of India are just same... But on the other side, by law there is discrimination. By law women are seriously discriminated against on various levels, by law almost all the minorities are discriminated... A professor has been given a death sentence for blasphemy because he wrote something online which the religion does not like. Such things are not possible in this country," he said.
Tags: nrc, caa, sadhguru, pm modi
Location: India, Delhi, New Delhi


text:
Warhammer Age of Sigmar: Champions Nintendo Switch Review
Posted by Keith Lavelle | Apr 26, 2019 | free-to-play, Reviews | 0
WARHAMMER: Age Of Sigma Champions Switch Review by SwitchWatch
Developer: Game Workshop, PlayFusion
Publisher: PlayFusion
Download Size 464MB
Price as of Article: FREE!
Game code provided by PlayFusion
ESRB: TEEN, PEGI: 12
Warhammer Age of Sigmar: Champions does not have a story, so let's move on.
Warhammer Age of Sigmar: Champions, as its name suggests, is based off of the popular trading card game of the same name. With thousands of players already invested in the trading card game, it seems only logical to bring it to the Switch. I have, however, a slight feeling this game is going to split its fan base.
Free-to-Play or Pay-to-win?
Firstly I want to get this out of the way, as it drags down what is an excellent tactical board game. So what do I mean by free-to-play? It is that the game is entirely free to download and start. I am sure we have all had the joys and annoyances of mobile games that are free but the grind is immense and the progression is slow, that just about sums up Warhammer Age of Sigmar: Champions. Even if it is slightly faster than a mobile game.
With Warhammer Age of Sigmar: Champions taking a mobile approach to the game, its geared to the players who want cards quick and not the time to earn the cards. So it may be more of a grind than other games that you pay for. This is no doubt to make paying for the crystals more appealing and get the super advertised spell card that can only be bought with crystals.
Taking this approach then makes the game pay-to-win, in the sense that people will pay real money for these cards and packs. I dislike this practice in games, which is why I do not play mobile games (crystals can be earned in the game also.)
This way of playing will no doubt split the fan base into three categories;
First: The players of the card game that the belief is physical is the only way to play.
Second: The fans who don't mind the free-to-play mobile model as they will grind away or pay for the good cards.
Third: The fans who do not like the mobile gaming practice who might try it then never look back (this is me).
Splitting the fans this way is going to make or break this game. I, for one, would have instead liked to have gotten the game and paid for it and cards are all there with no money needed to unlock them, like in the Yu-Gi-Oh games.
Now that I got the bad out of the way, let's move on to the good.
The board game is really good. It is also super simple to play and understand the basics and the core mechanics; this is always a plus in a board game. There is a short tutorial that explains everything within three matches; once done you will have the core mechanics down. If you have not played Warhammer Age of Sigmar: Champions before, do the tutorial.
When entering a match, the first port of call is to pick the deck you want to use. There are;
Order – The humans, these are standard cards with buffing abilities
Chaos – Twisted abominations from the warp, cause big damage at the cost of own life
Death – The undead, cause decks to be reshuffled
Destruction – The green skins, piling on Orks for multiple damages
It to me seems how the starting decks play. Of course, these decks can be customised to your liking once the right card is collected or bought.
On to the board, as shown above, there are four spaces each, health pool on the left and the deck to the right. Firstly, you will need to place your champions; these are the first four pictures you see on the board. The champions determine what cards can be played, these are: Warrior allowing damage dealing cards to be played, Wizard uses spell cards, and Warrior-Wizard uses both types of spells.
More About Champions
Champions determine how your own game will flow. Firstly, allowing certain types of cards to be played. Along with that, some have special abilities that can be used once per game, for instance, give 4 health.
By far the biggest thing that needs to be considered, and this makes the game really tactical, is the champion's missions. These are displayed on the square next to the champion and consist of four icons on each with its own objective, once all for objectives have been completed, the champions and unleash a special ability. The champions quest are;
1. Deploy a Unit (show by a red shield)
2. Deploy a spell (blue swirl)
3. Play an ability (white sword)
4. Deal damage (orange explosion)
5. Gain health (green bottle)
6. Remove a card (a square with an x in it)
Making sure the card you place on each champion corresponds with the quest is the best way to play.
Once the champions are placed, you draw four cards, then it is time to place cards. A player can perform two moves per turn, after which the turn is over and its the opponents turn. If you want to skip the turn without making a move, then two cards can be drawn, if one move is performed one card will be drawn. The opponent does the same and so on till one player has no cards or zero health.
Cards have numbers or X places at the corners; these indicate damage or no attack. These indicators rotate each turn until they hit a blank space then it is discarded. Some cards have special abilities, such as remove the opposite card to your card or lower damage received.
All this is just the general basics of the game summed up. There is a lot more to the game, but if i were to talk about it, I would be here for hours. If you would like to see the full set of rules, I linked them here.
Overall, the game is entertaining and tactical once you know the rules of the cards and are understood, and finding the right deck for yourself. I prefer Order, followed by Death.
If you already play the Warhammer Age of Sigmar: Champions card game, it is possible to scan in all your cards and use them in the game as well. Game Workshop is looking out for the fans at least. It is a massive plus for the people who play the card game but find it hard to get to events. I am sure a lot of players will find this exciting.
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The sounds effects are nothing special, nor is the soundtrack. They are not bad, just do not add much to the game, and let us be honest, who plays a board game for the sound effects or music?
Visuals & Performance
Warhammer Age of Sigmar: Champions does not have a lot of moving parts, so graphically it is good. Everything on the screen is crisp, clear, and smooth. Easily the most stand out element for me was the level of detail in each of the cards, some of them are stunning to look at.
As for performance, I found nothing wrong per se, just one little thing in the design of the game – the placing and using of the cards animation is so long feeling and breaks the games flow. Other than that, everything was smooth sailing.
Warhammer Age of Sigmar: Champions is a free game; nothing is stopping you in at least trying it.
The pay-to-win model might put some people off, it did for me. Unless you want to grind for loot boxes and money to buy new cards, then paying is the only way to progress quicker. I have never liked this gameplay archetype, and I don't think I ever will.
Enjoyable and fun
Easy to pick and play
Scan in physical cards
Mobile free-to-play style
Long wait for cards to be played
Summary Warhammer Age of Sigmar: Champions is a great board game; I can not fault the game for the fun and enjoyment of anyone who likes card games or board games will have. It is also entirely free-to-play, throw in the fact that the physical card can be used, you have a must for all Sigmar players. However, if you do not have cards, get ready to play A LOT as it has adopted the free mobile game way of making money with crystals. If you can look past this and don't mind grinding, this is a must play.
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Keith Lavelle
Played too many games if that is a thing. Love (J)RPG's, as well as small obscure indie games but will play most things. Check kickstarter too much. My family is my world.
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Insects are exposed to a wide range of microorganisms (bacteria, fungi, parasites and viruses) and have interconnected powerful immune reactions. Although insects lack an acquired immune system they have well-developed innate immune defences that allow a general and rapid response to infectious agents.
Over the last few decades we have observed a dramatic increase in the knowledge of insect innate immunity, which relies on both humoral and cellular responses. However, innate reactions to natural insect pathogens and insect-transmitted pathogens, such as parasites, still remain poorly understood.
In this review, we briefly introduce the general immune system of insects and highlight our current knowledge of these reactions focusing on the interactions of Trypanosoma rangeli with Rhodnius prolixus, an important model for innate immunity investigation.
There are two types of innate immune reactions: (i) the humoral response that is related to antimicrobial peptides, lectins and the prophenoloxidase (PPO) cascade and (ii) the cellular response which includes phagocytosis, hemocytes aggregation and encapsulation of pathogens.
Innate immunity of insects relies on a limited variety of receptors which recognize specific compounds that are on the surface of microorganisms or are released by them. The most well known pathogen-associated molecular patterns (PAMPs) are microbial cell-wall components like lipopolysaccharides (LPS) of Gram-negative bacteria, lipoteichoic acid and peptidoglycans of Gram-positive bacteria, β-1,3 glucans from fungi as well as glycosylphosphatidylinositol (GPI) from protozoan parasites [1, 2].
The humoral immune system recognizes PAMPs by pattern recognition receptors which are conserved in evolution to bind unique products of microbial metabolism not produced by the host [1, 2]. The humoral pattern recognition receptors such as LPS-binding proteins, peptidoglycan recognition proteins (PGRPs), Gram-negative binding proteins (GNBPs), β1,3-glucans recognition protein (βGRP), circulates in the hemolymph of insects [3, 4].
In the hemocyte surface there are several proteins implicated in the cellular immune response against invading microbes by recognizing the PAMPs. The most well known cellular receptors involved in recognition of pathogens in several insect species are croquemort (homologue of the mammalian CD36 family), Down syndrome cell-adhesion molecule (Dscam), peptidoglycan recognition protein (PGRP-LC), Eater (transmembrane protein) and the Toll family members [3, 4].
Drosophila melanogaster, a dipteran, has become an appropriate model for the investigation of immune pathways and insect-microorganism interactions [4–6]. Apparently, the main components of the core signaling processes are conserved between insects . The genome sequencing of these insects allowed a comparative genomic analysis of the gene families involved in the Drosophila defence reactions . The best-characterized insect humoral response is the production of antimicrobial peptides (AMPs). These peptides are small, cationic and with different structures. They are released into the hemolymph during infection . The main source of AMPs is from the fat body, but several epithelia and insect organs are also able to produce these substances . The most important AMPs are defensins which act mainly against Gram-positive bacteria . However, cecropins that have a large spectrum are more effective against Gram-negative bacteria . There are other AMPs like attacin, diptericin, drosocin and drosomycin, etc [5, 12]. Most AMPs have simple and non-specific modes of antibiotic action, such as driving pathogen membrane disruption by altering the membrane permeabilization or through an intracellular target [10–12].
Investigation in Drosophila demonstrated that production of AMPs is related to two distinct pathways: Toll and IMD pathways . Recent studies suggested that these two pathways respond respectively to Gram-positive or Gram-negative bacteria and fungal infections in insects [5, 12]. A third pathway involved in immune reactions, especially in mammals, is the JAK/STAT (Janus kinase/Signal transducer and activator of transcription) . The JAK/STAT signaling pathway takes place mainly in the fat body of insects. The production of AMPs is a common result of JAK/STAT, Toll and Imd pathway activity  (Figure 1).
Toll, IMD and JAK-STAT pathways. Insect tissues recognize pathogen-associated molecular patterns (PAMPs) by transmembrane receptors (DOME, Toll and PGRPs) in plasmatic membrane (PM) that activate the three pathways. The JAK-STAT pathway is activated by the receptor DOME (domeless) that transduces the signal to JAK and the cytosolic STAT. The Toll pathway starts with activation of the receptor Toll that signals to the cleavage of Dorsal-related immunity factor (DIF) complex releasing DIF. The IMD pathway through peptidoglycan recognition proteins (PGRPs) activates IMD (immune deficiency) that regulates the proteolytic cleavage and activation of Relish. The transcription factors (STAT, DIF and Relish) translocate to the nucleus through the nuclear membrine activating the expression of its transcriptional targets resulting in the production of antimicrobial peptides and other immune responses.
The prophenoloxidase (PPO) cascade, which leads to melanization and production of highly reactive and toxic compounds (e.g. quinones), is another important humoral immune reaction in insects. Also, there are several papers reporting that phenoloxidase (PO) promotes cellular defence reaction like phagocytosis [for review see ]. Although in some cases, the melanization process is not important for clearing an infection, it is relevant for pathogen encapsulation . Melanization depends on tyrosine metabolism. The PPO activation cascade is composed of several proteins, including PPO, serine proteases and their zymogens, as well as proteinase inhibitors. The PPO cascade is set off by the recognition of PAMPs that leads to the activation of a serine protease cascade culminating in the limited proteolytic cleavage of PPO to produce active PO that catalyzes the oxidation of tyrosine to dihydroxyphenylalanine (DOPA) which is subsequently oxidized to form dopaquinone and dopamine quinone as well as 5, 6-dihydroxyindole which have highly antibacterial activities (Figure 2). These compounds are precursors of the melanin polymer which is deposited on the surface of encapsulated parasites, hemocyte nodules and wound sites . Besides the PPO activation cascade is regulated by plasma serine protease inhibitors (including members of the serpin superfamily) and active phenoloxidase (PO), this process being directly inhibited by proteinaceous factors [15, 16] (Figure 2). Such regulations are essential because the products of PO activity are potentially toxic to the host.
A serine proteinase cascade is activated when different receptors recognize pathogen-associated molecular patterns (PAMPs). These serine proteases hydrolyze and activate the prophenoloxidase-activating proteinase precursor (proPAP) to prophenoloxidase-activating proteinase (PAP) that can be inhibited by serpins (proteinase inhibitors). The enzyme PAP hydrolyses prophenoloxidase (PPO) releasing phenoloxidase (PO). PO oxidizes tyrosine to dihydroxyphenylalanine (DOPA) and subsequently into quinones, the precursors of melanin, cytotoxic products and encapsulation of pathogens.
Finally, the mosquito Anopheles stephensi, a natural vector of human malaria, limits parasite development with inducible synthesis of nitric oxide (NO). Elevated expression of A. stephensi NO synthase (NOS) that is highly homologous to other characterized NOS genes, occurs in the midgut and carcass soon after invasion of the midgut by Plasmodium . Interestingly, in the hemolymph the nitrite/nitrate ratios, and the products of NO synthesis are higher in Plasmodium-infected mosquitoes and the treatment with NOS inhibitor N-nitro-L-arginine methylester significantly increases the number of parasites in infected mosquitoes .
Insect cellular responses are mediated by circulating hemocytes, and they include phagocytosis, hemocytes aggregation and encapsulation. Insect phagocytosis refers to the process by which hemocytes recognize, internalize and destroy microorganismal invaders . In Drosophila, phagocytosis is performed mainly by plasmatocytes, while hemocyte aggregation and encapsulation are carried out by lamellocytes that attach, embrace and inactivate the invading organisms, which then die by asphyxiation or by free radical attack . Frequently, there is a local activation of the PPO cascade that cross-links the hemocyte aggregates and microorganisms in a melanin envelope.
Eicosanoids are oxygenated metabolites of arachidonic acid with a huge range of physiological functions in a diversity of organisms. Among the important functions ascribed to eicosanoids are the central role that they play in the inflammatory and immune defence reactions in mammals  and the mediation of cellular defence responses to bacterial infections in insects . In fact, results from over 20 insect species representing 5 orders indicated that eicosanoids mediate cellular immune reactions to bacterial infections . Stanley-Samuelson et al.  demonstrated, for the first time, that eicosanoids regulate bacterial clearance from the insect's hemolymph. Following this pioneering paper, much research has been done on the relation of eicosanoids in regulating the insect immune system, especially on the elimination of inoculated bacteria from the hemolymph by nodule formation, the major cellular immune response to bacterial infections in insects [21–24]. The decrease of arachidonic acid production due to dexamethasone effect on phospholipase A2 (PLA2) activity reflects on the products of the cyclooxygenase (COX) and lipoxygenase (LOX) pathways, diminishing both bacteria clearance  and nodulation  in insects. After that, the recognition of the biological significance of eicosanoids in signal transduction in insect immune responses rapidly increased  with studies of insects infected with bacteria and fungi [25–27], parasitoids , protozoa [29, 30] and viruses [31, 32].
Miller and Stanley  have shown that eicosanoid biosynthesis inhibitors have a direct effect on Manduca sexta hemocytes and Tunaz et al.  demonstrated that dexamethasone exerts its effect on insects by inhibiting PLA2. Investigations made by Mandato et al.  showed that eicosanoid biosynthesis inhibitors attenuated the PO activity in Galleria mellonella challenged with bacteria, and this inhibitory effect of dexamethasone was abolished by the addition of arachidonic acid (Figure 3). So, many models of insect species have been studied to expand and generalize the hypothesis that eicosanoids mediate the nodule formation in insect hemolymph during immune responses to bacterial, fungal, parasitoid and viral infections.
Phospholipids are hydrolyzed by phospholipase A 2 liberating arachidonic acid and Lyso-PAF, regulators of insect's immune system. Arachidonic acid is the substrate for eicosanoid production, prostaglandins via cyclooxygenase and leukotrienes via lipoxygenase. Lyso-PAF is acetylated by PAF-acetyl transferase releasing PAF that can be degraded by PAF-acetyl hydrolase that hydrolyses PAF regenerating Lyso-PAF. In the presence of dexamethasone the immune responses are inhibited due to the suppression of phospholipase A2 activity with lower production of eicosanoids and PAF. On the other hand when exogenous arachidonic acid is added there is enhancement of eicosanoid production and immune responses increase.
Some invading microorganisms induce an immunological depression to avoid the immune reactions of insects. The entomopathogenic bacterium, Xenorhabdus nematophila, induces immunodepression in target insects by (PLA2) activity inhibition causing lethal septicemia of the infected hosts [35–37].
Trypanosomes are digenetic parasites that have insects as vectors and infect human beings and other vertebrates as hosts . So far, only species of the genus Rhodnius have presented infective forms of Trypanosoma rangeli in their salivary glands . In Latin America, this parasite has two major lineages based on kinetoplast DNA (kDNA) markers: one group presents three types of kDNA minicircles (KP1, KP2 and KP3- T. rangeli KP1+), while the other group has only KP2 and KP3 minicircles (T. rangeli KP1-) [for review ]. T. rangeli is a harmless parasite for humans and various wild and domestic animals, but it can be pathogenic to the insect vector .
While the full biological cycle of Trypanosoma cruzi, the causative agent of Chagas disease, takes place in the guts of the triatomine vectors, and the infecting parasites are eliminated with feces and urine to contaminate vertebrate hosts [41–44], the T. rangeli life cycle in the vector is different. The vector infection begins when parasitesare ingested as trypomastigote forms. The parasites multiply as epimastigotes in the gut, and they are able to penetrate through the gut epithelium  (Figure 4) invading the hemocele. In the regular course of infection, a few days after parasite ingestion, short epimastigote forms appear in the insect hemolymph. Soon, they disappear to be replaced by a massive colonization by long epimastigotes . The epimastigotes survive in the hemolymph and/or inside the hemocytes. Then, they migrate and possibly by recognition of carbohydrate moieties attach to salivary glands , invade them and complete their development into infective forms [48–50] (Figure 4).
Scheme of biological cycle of Trypanosoma rangeli within its insect vector. The insect feeds on blood infected with trypomastigote forms which differentiate to epimastigotes in the midgut (white arrows) where they multiply (1). Some epimastigotes invade the hemolymph through the gut epithelium (red arrow). Long and short forms of epimastigotes can entry into the hemocytes and multiply or replicate in the plasma (2). Some parasites invade the salivary glands (blue arrow) and differentiate to trypomastigotes which will be transmitted when the insect-vector feeds on another host (3).
Interestingly, Garcia et al.  described that T. rangeli impairs R. prolixus salivary gland function, preventing full expression of its antihemostatic machinery  prolonging the duration of intradermal probing.
Rhodnius belongs to the subfamily Triatominae of the family Reduviidae that is made up of 140 species of triatomines, several of which are vectors or potential vectors of the hemoflagellate protozoan parasites T. cruzi and T. rangeli. However, only species of the genus Rhodnius have infective forms of T. rangeli in their salivary glands [48, 52].
Since the main characteristic of the T. rangeli life cycle is the invasion of the insect hemocele it must overcome the immune reactions of its vector. We will therefore use the bloodsucking bug, Rhodnius prolixus, as a tool for providing insights into how insects defend themselves against infection by bacteria and parasites such as T. rangeli. From a practical point of view, R. prolixus has many advantages as an insect model for research on parasite transmission. These include simple maintenance and rearing in the laboratory and feeding through an artificial membrane device. This facilitates the infection with parasites and, due the body size, they are easily handled and manipulated [42, 53]. Besides that, R. prolixus is frequently used for physiological studies [54, 55] and, more recently, for biochemical and immunological investigations . Nevertheless, there is a great lack of molecular data about the R. prolixus immune system, and the majority of studies focused in the cellular response or in the effects of the vector immune defences in the parasite development (and vice versa). However, the sequencing of its complete genome (670 MBp)  will facilitate the application of advanced molecular biology to enhance ongoing research for exploration of biomedical significance of this insect.
Knowledge on the Rhodnius immune system and its activation in response to microorganism infections has grown in recent years. The first defences against microbiological infections are the structural barriers outside or inside the body (for example, exoskeleton and the perimicrovillar membrane in the midgut [55, 57–59].
The establishment of T. rangeli infection in both gut and hemocele of the insect vector is possibly regulated by a range of biochemical and physiological processes. The first environment for the transformation and development of T. rangeli is in the gut. There the parasites are confronted with anterior and posterior midgut components and products of blood digestion. These included bacteria [60, 61], hemolytic factors  and lectins [46, 63], all of which may modulate the infection of T. rangeli in the vector gut.
Once in the hemocele, T. rangeli must overcome the robust insect vector's defence system including lysozymes and trypanolytic activities , PPO activation , phagocytosis and hemocyte microaggregate formations [29, 30, 65–67], agglutination [46, 63], superoxide and nitric oxide production  and a trypanolytic protein which acts specifically against the T. rangeli KP1-strains . All these activities seem to act as biological barriers raising difficulties for the development and transmission of the parasite in the vector.
Although Lopez et al.  showed that defensin was induced both in the hemolymph and midgut of R. prolixus by inoculation of Escherichia coli and Microccocus luteus, there are some data on the inactivation of the R. prolixus humoral immune system by parasite infection. Mello et al.  demonstrated that, after systemic inoculation of T. rangeli short epimastigotes into the hemocele of R. prolixus, the parasite produces a high intensity of infection through successive division during the extracellular development, with a concomitant increased levels in the lysozyme activity in the hemolymph. They also showed that T. rangeli infection induced neither trypanolytic nor peptide antibacterial activities, but a galactose-binding lectin from R. prolixus hemolymph, which enhanced the activation of clump formation by T. rangeli in R. prolixus hemocyte monolayers. An increase in clump size and hemocyte aggregation was also described . This purified lectin also affected in vitro the motility and survival of T. rangeli culture short forms, but not the long forms , which are predominant in the hemolymph two days after inoculation .
Another important biological event of T. rangeli interference in the insect immune reactions is its ability to activate the PPO system of R. prolixus. Gregorio and Ratcliffe [71, 72] demonstrated that Triatoma infestans, but not R. prolixus, presents a very active PPO system when activated by laminarin and lipopolysaccharides. For both species of insects, neither T. rangeli from culture nor parasite lysates were able to trigger PPO activation in vitro. However, the presence of the parasite in R. prolixus hemolymph assays reduced the level of PPO activation by laminarin. These authors suggest that the susceptibility of R. prolixus to T. rangeli hemolymph infection may, at least in part, be explained by the suppression of the inset immune defence system i.e. inhibition of the PPO cascade in the presence of this parasite.
Interestingly, Gomes et al.  clearly demonstrated using in vitro experiments that the activation of the PPO pathway occurred when the hemolymph was incubated with fat body homogenates and short epimastigote forms of T. rangeli. The same authors using in vivo experiments showed that short, but not long, epimastigote forms activated directly the formation of melanin . In addition, the PPO-activating pathway was suppressed when insects, which had been fed on blood containing either short or long epimastigotes, were challenged by thoracic inoculation of the short forms. This indicates that the reduction of the PO activity was a result of parasite ingestion. The PPO pathway is activated when glycosylphosphatidylinositol (GPI) anchors, specifically glycoinositolphospholipids (GIPLs) and GPI-mucins purified from T. rangeli epimastigotes, are inoculated in the insect .
One factor that can be important for killing T. rangeli is nitric oxide and nitrite/nitrate radicals, products of NO synthase (NOS) activity. Whitten et al.  described experiments to demonstrate whether or not nitric oxide and superoxide production could operate during T. rangeli infection in R. prolixus. These authors followed the inoculation of two strains and two developmental forms of T. rangeli after 24 h. When the H14 strain was inoculated, the parasites failed to multiply and invade the salivary glands whilst the Choachi strain rapidly multiplied in the hemolymph to invade salivary glands. However, in insects inoculated with H14 strain, the levels of PPO and superoxide generated by R. prolixus were significantly higher than Choachi strain, and nitrite and nitrate levels were also much higher with H14 inoculations. Usually, short forms of epimastigotes stimulated greater superoxide and PPO reactions than long epimastigotes in both parasite strains in the hemolymph of R. prolixus. Furthermore, when the NADPH oxidase inhibitor, N-ethylmaleimide, or the inhibitor of the inducible nitric oxide synthase, S-methylisothiourea sulfamide, are injected into R. prolixus, they resulted in higher insect mortality after T. rangeli infection of either strains compared with those untreated controls . Whitten et al.  demonstrated that the most pronounced reactions to crude LPS occurred in the R. prolixus fat body and hemocytes, while tissues of the digestive tract were most responsive to infections by T. cruzi and T. rangeli. This suggests that the NO-mediated immune responses in this insect are pathogen specific and independently modified both at the transcriptional and NO synthase gene expression.
It is interesting to note that in a screening of R. prolixus genes activated after T. cruzi infection by sequencing of subtractive libraries, no genes related to the humoral immune response were found to be transcriptionally upregulated . These results suggest that the R. prolixus immune responses to parasites are not mediated by AMPs, and could be centered in hemocytes nodulation, encapsulation and phagocytosis. The comparison between the responses against bacteria and T. cruzi also showed that R. prolixus activates different mechanisms of defence depending on the pathogen . In this way, it is possible that the regulation of immune related genes in R. prolixus differs significantly after T. cruzi or T. rangeli infection.
The circulating hemocytes are essential for the insect immunity. In R. prolixus seven morphological hemocyte types were identified by phase-contrast microscopy: prohemocytes, granulocytes, plasmatocytes, cystocytes, oenocytes and adipohemocytes and giant cells . Some cellular immune reactions have been studied in T. rangeli-triatomine interactions. Garcia et al. , demonstrated for the first time that eicosanoid biosynthesis inhibitors applied to R. prolixus strongly affect hemocyte microaggregation, one of the cellular immune reactions. The main data found by these authors were: (i) insects that had previously been fed on blood containing biosynthesis inhibitors of PLA2 (dexamethasone) and COX (indomethacin) and non-selective LOX inhibitor (nordihydroguaiaretic acid, NDGA) showed a significant increase in the number of free epimastigote forms of T. rangeli in the hemolymph and, consequently, increased lethality; and (ii) the parasite infection in insects treated with these compounds led to less hemocyte microaggregation and attenuated the activation of PPO system in the hemolymph.
Garcia et al.  suggest that arachidonic acid was not available in insects treated with dexamethasone. Indeed, the application of arachidonic acid significantly enhanced both hemocyte microaggregation and PO activity in the hemolymph of insects previously treated with dexamethasone and challenged with parasites. It also reduced the number of parasites in the circulation and the mortality of insects. The effects of indomethacin and NDGA were considered relevant because they indicated the influence of multiple eicosanoid metabolites in immune reactions of R. prolixus infected with T. rangeli. Furthermore, hemocelic inoculation of epimastigotes of T. rangeli into larvae of R. prolixus previously fed with blood containing the same parasite, demonstrated a reduced number of hemocyte microaggregates, enhanced the number of parasites in the hemolymph as well as increased the mortality of these insects. All these effects were counteracted by combined injection of R. prolixus with T. rangeli and arachidonic acid . These results suggest that the arachidonic acid pathway can be a mediator of hemocyte microaggregation reactions in the hemolymph of insects inoculated with T. rangeli and that oral infection with this protozoan inhibits the release of arachidonic acid (Figure 3).
One interesting novelty of this parasite-vector interaction was revealed by Machado et al. . They demonstrated that hemocelic injection of short T. rangeli epimastigotes in R. prolixus that were previously fed with blood containing WEB 2086 [a strong platelet-activating factor (2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine (PAF) antagonist] resulted in reduced hemocyte microaggregation, attenuated PPO activation in the hemolymph as well as increased the parasitemia and insect mortality. Nevertheless, simultaneous application of PAF did not counteract hemocytes microaggregation and PO activity.
It was demonstrated that physalin B, a natural secosteroidal chemical from Physalis angulata, induces immunodepression in R. prolixus [80–82] and strongly blocks hemocyte phagocytosis and microaggregate formations in R. prolixus . The inhibition induced by physalin B was counteracted for both phagocytosis and microaggregation of hemocytes by arachidonic acid or PAF applied by hemocelic injection. Physalin B did not alter hemocyte PLA2 activities but it significantly enhanced PAF-acetyl hydrolase (PAF-AH) activity in the cell free hemolymph and hemocytes. Theses findings reinforce the importance of PAF and arachidonic acid pathways in cellular immune reactions in R. prolixus (Figure 3).
The most exciting outcome in the investigation of T. rangeli in triatomines is the PAF influence on the hemocyte nodulation  and phagocytic responses of R. prolixus hemocytes against Saccharomyces cerevisiae [66, 67]. These authors evaluated the effects of PAF and eicosanoids in the phagocytosis in hemocyte monolayers (the main cell type implicated in this process is plasmatocytes) of R. prolixus against the yeast S. cerevisiae. The experiments demonstrated that the phagocytosis of yeast cells by Rhodnius hemocytes is very efficient in both controls and cells treated with PAF or arachidonic acid. However, phagocytosis of yeast particles is significantly diminished when the specific inhibitor of PLA2, dexamethasone, is applied to the hemocytes. By contrast, dexamethasone pre-treated hemocyte monolayers exhibit a drastic enhancement in the quantity of yeast cell-hemocyte internalizations when the cells are treated with arachidonic acid. Phagocytosis decreases expressively in hemocyte monolayers treated with WEB 2086, a specific PAF receptor antagonist. Nevertheless, a decrease of phagocytosis with WEB 2086 is also counteracted by the treatment with PAF [66, 67]. The authors suggest that these data on phagocytosis of yeast cells by hemocytes are related to the activation of PAF receptors and provides a novel insight into the cell signaling pathway of non-self recognition related to cellular immune reactions in the insect-parasite relationship.
Finally, Figueiredo et al.  demonstrated that hemocyte phagocytosis was significantly reduced by oral infection with T. rangeli. These authors demonstrated that hemocyte phagocytosis inhibition caused by the parasite infection was rescued by exogenous arachidonic acid or PAF applied by hemocelic injection. They also observed an attenuation of PLA2 activities in R. prolixus hemocytes (cytosolic PLA2: cPLA2, secreted PLA2: sPLA2 and Ca++-independent PLA2: iPLA2) and an increase of sPLA2 in cell-free hemolymph. At the same time, the PAF-AH activity in the cell-free hemolymph enhanced considerably. These data suggest that T. rangeli infection depresses eicosanoids and insect PAF analogous (iPAF) pathways giving support to the role of PLA2 in the modulation of arachidonic acid and iPAF biosynthesis and of PAF-acetylhydrolase (PAF-AH) by reducing the concentration of iPAF in R. prolixus . The relationship between the expression of the genes of PLA2 and PAF-AH as well as general cellular responses and signal transduction pathways is poorly understood in hemipterans. In this way, it is difficult to interpret the T. rangeli immunosuppression in terms of regulation of cellular signal transduction cascades. The data above suggest an inhibition of the NF-κB pathway, one well known effect of physalin treatment in mammal cells . This is in agreement with the inhibition of the humoral immune response, but more detailed studies on the molecular mechanisms are needed to clarify this point.
All these finding illustrate the ability of T. rangeli to modulate the cellular immune responses of R. prolixus to favor its own multiplication in the hemolymph.
Interventions to study the triatomine vector biology may be useful to develop new concepts and means to block parasite transmission, both of which are urgent and necessary. The recent investigations into R. prolixus immune reactions relating to T. rangeli development have established a new conceptual hypothesis: a fine modulation of insect factors can interfere with parasite development and this is important for the establishment of infection, being an attractive target for intervention (Fig. 5).
A schematic illustration of Trypanosoma rangeli regulating the Rhodnius prolixus immune reactions. White arrows (↓) indicate immune reactions decrease after infection of R. prolixus with T. rangeli. In the case of AMP production by R. prolixus, there is no known (?) regulation by T. rangeli.
Despite the progress in understanding the complexity of the insect immune responses, our knowledge of this theme in hemipteran vectors remains far from complete. Much work is still needed to understand the successful transmission of protozoans as the result of the immune modulation, as caused by T. rangeli infection in R. prolixus. It is necessary to understand humoral and hemocytes-surface receptors and regulators and intracellular signaling molecules to permit the development of new immunomodulatory drugs, designed to control vector insect's populations.
Finally, another point to be considered is that for triatomines the limited use of molecular biology technology has permitted only a fragmented view of the immune defence system in this important Chagas disease vector. Moreover, advances in Rhodnius genomics and functional genomics in the near future will lead to a rapid development of this field. The study of genes involved in immune reactions will reinforce the need to better understand the defence responses related to parasite-vector interactions.
Funding for this work was provided by the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) to ESG and PA, Fundação Oswaldo Cruz (FIOCRUZ) (Papes Project to PA) and Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) to PA and FAG. ESG and PA are CNPq Senior Research Fellows. DPC is a post-doc researcher of FIOCRUZ and MBF is a post-graduate student from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). We thank Gutemberg Brito for R. prolixus picture used in Figure 5.


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Wonder Woman Director Shares Sequel Ideas
Wonder Woman director Patty Jenkins says she is already thinking about ideas for a sequel, with Diana Prince coming to America.
by Timothy Lammers
Even though the release of Wonder Woman is a little over a month out, director Patty Jenkins says she is already thinking about ideas for a sequel. Starring Gal Gadot in the titular role, the DCEU origins movie about the Amazon warrior princess – set to debut in theaters June 2 – has been a long time in the making. Lynda Carter, of course, made the DC Comics superhero famous in live-action form with the ABC TV series in the 1970s, and sadly, an attempt to bring the character back to TV in 2011 with Adrienne Palicki in the lead, fell short.
Wonder Woman's fortunes changed, though, when she made a gallant entrance in 2016's Batman V Superman: Dawn of Justice, and Jenkins wants to keep the momentum rolling following the release of the character's solo movie – which traces Wonder Woman's roots back to the early 20th century on the sheltered island paradise of Themyscira. In an interview with the Toronto Sun, Jenkins shares her ideas for a sequel:
"I'm excited for her to come to America and become the Wonder Woman we are all familiar with from having grown up around her as an American superhero. I'd like to bring her a little farther along into the future and have a fun, exciting storyline that is its own thing. Wonder Woman 1 is so much about her becoming the person she is. I can't wait to spring forward with who she is and have another great standalone superhero film."
That's not to say Jenkins regrets the Wonder Woman goes the origins route in the first film, since an origins story – which she says is something she's wanted to do for 10 years – is necessary to get a full understanding of the character. Jenkins says:
"I always thought the origin story would be the great way to go. I love origin superhero stories and I love the simplicity you can have with that journey. Also, there was the fact that no one had done her story and the fact that I love her. So it was a treasure trove of potential."
Since the character is vital in the upcoming Justice League movies, Jenkins knows it may be quite a while before the opportunity to direct Wonder Woman 2. But, the Sun says, no longer how long another movie takes, it won't prevent Jenkins from coming back to the franchise.
With any luck, Warner Bros. won't waste any time locking in a date for a Wonder Woman sequel and keeping Jenkins on board. She's already attracted the attention of Dwayne Johnson for his Disney film Jungle Cruise, who says he's a big fan of the helmer. With her DCEU experience, could The Rock be thinking of Jenkins to direct a Black Adam solo movie, too?
Next: 2017 Summer Movie Preview: The 20 Films to See
Source: Toronto Sun
Key Release Dates
Wonder Woman (2017) release date: Jun 02, 2017
Justice League (2017) release date: Nov 17, 2017
The Batman (2021) release date: Jun 25, 2021
Cyborg (2020) release date: Apr 03, 2020
Aquaman (2018) release date: Dec 21, 2018
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Washington Airport Receives New Firefighting Station
12 August 2009	(Last Updated August 12th, 2009 18:30)
Bellingham International Airport in the US has opened a new $2.7m airport rescue firefighting Station to improve its emergency response capabilities. The 7,550m² station includes a communications room, a training room and three equipment bays. The facility will follow safety
Bellingham International Airport in the US has opened a new $2.7m airport rescue firefighting Station to improve its emergency response capabilities.
The 7,550m² station includes a communications room, a training room and three equipment bays.
The facility will follow safety regulations for the airport's present and future size classification.
The Federal Aviation Administration has financed over 95% of the project's design and construction costs.
Tiger Construction is handling the building work, which is expected to finish next week following almost a year of work.
TCR International
Ground Support Equipment Rental and Maintenance Solutions
Gate Technologies AF Ltd
Airport Public Service Counters, and Baggage Handling and FIDS Solutions


It would be needless to mention that the medical science always looks for new and advanced technologies and this is because the things are turning in favor of patients. Let's discuss some of the latest advancements in health care sector.
It is considered to be one of the biggest advancements in the field of medical science. Now, most of the healthcare devices are getting rid of wires and cords and patients can check their status on the go. As per the latest market reports from R&R, the global market for mHealth will cross the mark of $20.7 billion within 2019. Now, this is an amazing advancement in itself.
Portal technology is one such technology which is becoming highly helpful for patients who have becomes active players in maintaining their own health. With the help of this technology, doctors and physicians can interact with the patients and assess their medical records online.
The conclusion of 2012 witnessed that there were 2.8 million patients worldwide using home monitoring system. The best thing about this system is that it minimizes the cost of visiting doctor's clinic.
These are some of the recent and latest technological advancements in the field of medical science. Apart from these, some other advancement are also helping patients to lead a healthy life such as self-service kiosks, telemedicine, wearable technology, etc.


Spent the weekend painting and working on the temporary FFDG space at 248 Clement.
Damn, it takes a lot of paint (and beer) to paint 2,500 square feet... And I'll tell you what, it doesn't matter what day it is, Burma Superstar has a line out front from like 5pm till 10pm. People go bonkers for that place, and well, because it's damn tasty.
Christen with friends and beers.
Gallery must be large enough for bike fun.


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Back to school with Medeia Cohan-Petrolino
Posted by Lorena Muñoz-Alonso	on 15th August 2011
Talk about experience! Rise Art Curator Medeia Cohan spent more than 5 years running the Emerging Artist Programme as Head Curator at the University of the Arts London, and the Alumni Relations department. It's not hard to image the extensive understanding of the needs and hopes of emerging artists she gathered there, as well as the peculiarities of the art industry. An asset she is now using in her new exciting role as Programme Director at School for Creative Startups, where she currently works with former Dragon's Den panellist Doug Richard to design a state of the art one year programme to teach creative people how to realise their business ideas.
Medeia Cohan-Petrolino
So what exactly is the School For Creative Startups and how exactly does it help young, creative people?
The aim of the programme is to teach the critical skills that new creative businesses need to succeed and to provide support throughout the vulnerable first year of business. We provide accelerated business training that helps any age and any stage entrepreneurs launch more successful startups and run more successful businesses through a tailor made one-year programme. We have face-to-face and online lessons, business networking events to connect small businesses and create supportive, self-sustaining communities. We also have mentor schemes that provide one to one advice from industry experts… Pretty much everything you need to know to start your creative business!
What was most exciting and challenging thing about running the Emerging Artist Programme of the UAL?
The most exciting thing about it is in fact very similar to what excites me about working in the School for Creative Startups: discovering and nurturing talent. Getting to be involved at ground level and helping to build something and watch it grow is a really satisfying feeling. Whether it's an individual artist or a small startup the pleasure in helping people achieve their goals is always immense.
Print by Mike Ballard, one of the artists in Medeia's collection
Do you collect art yourself? Could you name some of your favourite artists?
I collect emerging art and design. I have a range of mediums in my collection including print, sculpture and painting. My favourite pieces include a concrete diptych sculpture piece by Alexander Hoda, a lovely painting by Christine Aerfeldt and several insane prints by mix media artist Mike Ballard
You have sound experience in working with and supporting emerging artist, and have been involved with Rise Art from the very beginning as a curator. What do you think that makes this company special?
Rise Art has many strengths, but the thing that differentiates them most from their competitors is a caring and committed staff base from which the company was built. It was easy to get on board with a site where critics, curators and peers are encouraged to vote and feedback to the showing artists. Additionally as the site grows the selection of work is becoming really interesting and of a certain calibre which is exciting.
Painting by Christine Aerfeldt, another artist in Medeia's collection
Why did you decide to work in the art world and what would be your advise to someone who wants to work in this difficult industry?
I have worked in lots of different sectors and the creative industries are by far the most exciting and fulfilling. I believe that this is a steadily growing area and the one that will start the reinvigoration of the economy in the UK, so it's the right time to get in. My advice is if you love the arts and want to work in this field, do it! It is wonderfully rewarding in many other ways that will compensate for a glamorous office and massive salary. If you want to make a lot of money and like art, keep it as a hobby and get a desk job - it's really that simple!
What projects and ventures do you have coming up?
We launched School for Creative Startups on the 1st of July and we are now seeking applicants to attend the programme, which begins September 19th with an intense bootcamp with Doug Richard. I am so excited about S4CS because it's a life-changing programme teaching creative people how to live off their craft. I can't wait to get stuck in! I encourage anyone who might be interested to visit the website to learn more about what we're up to and apply now for a place on the course.
The School for Creative Startups' launched on the1st of July 2011
For more information, please visit the School for Creative Startups website.
The deadline to apply for this year's course is the 30th of August.
Lorena Muñoz-Alonso is a London-based writer and curator. She joined the team of Rise Art in early…
Lorena Muñoz-Alonso is a London-based writer and curator. She joined the team of Rise Art in early 2011 as Editorial Associate. She also writes for her site SelfSelector, is a featured editor of the online art magazine this is tomorrow and contributes to wide range of print and online publications like frieze.com, Kaleidoscope or AD (ES) amongst many others
Interview with Justin Hammond, curator of The Catlin Art Prize 14th January 2014
Memory, traces and the healing power of art: a conversation with Chris Shaw Hughes 19th January 2012
Interview with Select Artist Rosalind Davis 09th November 2011


My first opportunities to experience the elements unlike ever before were as a carefree high school student during two Youth Group wilderness trips to West Virginia. Each week-long trip was spent climbing, repelling, hiking, camping, and white water rafting. It was amazing, but not without mishaps either. When I say braving the outdoors unlike ever before, I'm referring to carrying my vacation home with me on my back, including: Parts of the camp (like the tent, stove, etc), sleeping arrangements, meals, apparel, toiletries, and everything else needed for the week. And no, there aren't bathrooms along the New River either; but don't worry, that's all I have to say about that.
No longer having the body and bounce-back of a teenager, and as an Asthmatic hiking up to an altitude over 14,000 ft with depleted oxygen levels, I've been trying to mentally and physically prepare for this unique experience. As I'm writing from an airplane traveling to Florida, I'm reminded how utterly different camping is from any other type of trip: Unlike packing for my current trip, every single item that goes with me to the 14,110-feet top of Pikes Peak will be seriously scrutinized and considered imperative for my well-being.
Ounces and pounds never mean quite as much as they do when they are strapped on your back while walking for a couple of days. Gear for backpacking is all about being resourceful and setting the right priorities. Ladies, the right priorities in this case do not include whether or not your shoes match your shirt.
My husband and I have been slowly collecting or buying gear over the past couple of years. (Yes, we are that couple who registered not only for dinnerware at Macy's but for camping gear at REI when we got engaged.) Even so, I still was lacking the basics in proper rustic camping gear; therefore, it's been primarily starting from scratch.
1. Don't over do it. You don't need every single small and large thing that packing lists, outfitter stores, or salespeople make you feel like you must have. Do your research, talk with friends that camp, and think through the essentials that pertain to: Staying dry, well-lit, properly adjusted to the climate, hydrated, fed, safe from elements and potentially dangerous wildlife, and to have methods of communication and tracking that work in the woods.
2. Not all camping is the same. Cabins as opposed to tent camping in a site with water & electricity, versus rustic camping that you drive your vehicle to, versus hiking to set up camp are all different; thus packing and preparations are varied as well. Our gear and packing will be a bit eclectic since our 12-day trip will be a mixture of hotels, staying with family/friends,1 night in a mountain cabin, and rustic camping.
(2) A good, 3-season, down-filled sleeping bag (Marmot, on Sale for $224.95+ shipping and tax). Down-filled bags are known for their warmth, loft (fluffiness), light-weight material, and durability.
(3) A 3-person tent (Köppen, again, on Sale for $85).
Mike and I will continue to refine our packing lists, because it really is about resourcefulness and correct prioritizing.
What camping or hiking gear have you found essential?
This is the second post in my Colorado Road Trip Series. You can read about my training here. Continue to track our outdoor adventure right here over the next 3 weeks.


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Home>Energy>Gas-to-Energy
Kleangas Energy to Buy Landfill Gas to Energy Operation
TAGS: Gas-to-Energy Mergers and Acquisitions
Kleangas Energy Technologies Inc. has made a filing with the Security Exchange Commission (SEC) to acquire an energy company that converts landfill gas to electricity.
The Tampa, Fla.-based Kleangas, an alternative energy company, has filed an 8K with the SEC for the plant that produces about 15,000 metric tons of pellets annually and generates 2.4 megawatts of electricity, according to a news release. The power is sold to a major utility company, and the facility also uses the heat generated from the landfill gas burning in the drying process to create wood pellets, which are used a fuel alternative to create electricity.
Kleangas said it will increase the production in both electricity and wood pellets during the next 12 months.


When we thin makeup, first thing that comes to mind is big bold lips! Thanks to Kylie Jenner, who has changed the entire definition of Makeup, Glam now a days is all about colored lipsticks. The girl has takes all risks possible as far is trying out different lipcolors is concerned. SO here are Top 5 Kylie Jenner bold lipcolors you must try in 2017.
If you read my other blog Being Beautiful and Pretty then you know already that I am a huge Kardashian-Jenner fan, not for their lifestyle choices but for their fancy wardrobes and on point makeup.
If you are a makeup enthusiast, you must give bold lipcolors a try. There Kylie Jenner lipcolors are a hot makeup trend for 2017.


The new Yankee Stadium opened in 2009, and there have been plenty of memorable moments during its first five years. From the Yankees capturing their 27th World Series title in 2009 to Derek Jeter joining the elite 3,000 hit club in 2011, here's a countdown of the top 10 greatest moments at the new Yankee Stadium -- so far.
July 16, 2010 was the Yankees first home game since the death of owner George Steinbrenner. Derek Jeter gave a moving speech at home plate before the game started, and the jumbo television in centerfield played Steinbrenner tributes between innings. With two outs and one on in the bottom of the ninth and the score tied at four, Nick Swisher hit a walk-off RBI single to give the Yankees a 5-4 win over the Tampa Bay Rays.
Down 3-2 to the Anaheim Angels in the bottom of the 11th of Game 2 of the American League Championship Series on Oct. 17, 2009, Alex Rodriguez hit a leadoff, game-tying solo home run off Angels closer Brian Fuentes. The Yankees went on to win 4-3 and take a 2-0 series lead.
Derek Jeter singled in the third inning against Baltimore Orioles pitcher Chris Tillman on Sept. 11, 2009 for hit number 2,722, moving him past Lou Gehrig and breaking the Yankees' all-time hit record.
With the ALDS against the Baltimore Orioles tied at 1-1 and the Orioles leading Game 3 by a run with one out in the ninth, Raul Ibanez was sent in to pinch-hit for the struggling Alex Rodriguez. It was an unprecedented move given Rodriguez's stature as one of the greatest sluggers in baseball history. But Ibanez made manager Joe Girardi look brilliant, hitting a home run to right field to tie the score. In the bottom of the 12th, Ibanez struck again, turning on the first pitch of his next at-bat to win the game.
New York Yankees pitcher Mariano Rivera leaves the field for the last time as a player at the close of his last game at Yankee Stadium on Sept. 26, 2013. With two outs left in the ninth and the Yankees up 2-1 on the Houston Astros, Derek Jeter and Andy Pettitte emerged from the dugout to take Rivera out of the game.
Down 3-1 to the Minnesota Twins in the bottom of the ninth of Game 2 of the American League Division Series on Oct. 9, 2009, Alex Rodriguez hit a one-out, two-run game-tying home run off Twins closer Joe Nathan to send the game into extra innings. In the 11th inning, Mark Teixeira hit a solo, walk-off home run to give the Yankees a 4-3 win and a 2-0 series lead.
On Nov. 4, 2009, Hideki Matsui exploded in Game 6 of the 2009 World Series, going 3-for-4 with 6 RBIs to lead the Yankees to a 7-3 win over the Philadelphia Phillies and their 27th World Series title. Matsui's heroics helped earn him World Series Most Valuable Player.
Mariano Rivera set the Major League Baseball all-time saves record with save No. 602 on Sept. 19, 2011. The save gave the Yankees a 6-4 win over the Minnesota Twins.
Derek Jeter hit a home run off Tampa Bay Rays pitcher David Price for his 3,000th career hit on July 9, 2011. Jeter became the first Yankee in franchise history to amass 3,000 hits. He also went 5-for-5 with the game-winning RBI single to lead the Yankees to a 5-4 win.
The New York Yankees won their 27th World Series championship on Nov. 4, 2009 after defeating the Philadelphia Phillies in six games.