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Lost Books of the Bible For Dummies Cheat Sheet
The Bible For Dummies Cheat Sheet
Women in the Bible For Dummies Cheat Sheet
Who Is Satan According to the Bible?
Reliving the Biblical Christmas Story
Learn some helpful terms regarding religious writings to explain the subject, and study a timeline of important events so you understand how the Hebrew Bible, Christian Old Testament, and New Testament were formed.
Handy Terms for Discussing Christian and Jewish Writings
Christian and Jewish religious writings encompass an amazing amount of work. To keep things straight when you're talking about or studying these writings, make sure you understand these helpful terms and what they mean:
Apocrypha: A Greek term that means "hidden," this is the name Protestants give to the group of books that Catholics include in their Old Testament but Protestants do not. Jews (that is, the early Rabbinic Leaders of modern Judaism) also don't include these books in their Hebrew Bible.
Canon: A Greek term that means "measuring stick" or "ruler," it came to be used in Christianity and Judaism to refer to a specific list of religious writings officially approved for study and worship.
Gnosticism: A religious and philosophical movement that emerged in the late-first and second century CE, it focuses on the origins of spiritual beings, Gods, and other near-divine beings that control human affairs. Some Gnostics became Christians, and some Jews were influenced by Gnosticism as well.
Hebrew Bible: Although it's the same thing as the Christian Old Testament, Hebrew Bible is a more respectful term that reminds Christians that, for Jews, the Hebrew Bible isn't merely an "Old" Testament that's replaced by a "New" one. In Jewish tradition, many Jews prefer to use the acronym "TaNaK" or "TaNaQ", which is built from the first word of the Hebrew names for the three sections of their Bible: Torah (Law), Neviim (Prophets), and Qtuvim (Writings).
Non-canonical writings: Most of the writings discussed in Lost Books of the Bible For Dummies are non-canonical because they aren't part of the list of canonical books in either the Jewish or Christian traditions. However, different Christian religions disagree about the canon of their Old Testament.
Scriptures: Any religious writing valued by a religious tradition. But scripture is a wider category than canon in that scriptures can be outside a canon.
Dates that Affected Development of the Hebrew Bible — a.k.a. the Old Testament
The Hebrew Bible and Old Testament are the same group of writings, although Jews prefer the term Hebrew Bible. These biblical writings are much older than the Christian New Testament writings. These dates represent important events that influenced how scripture (religiously important reference writings) led to the collection of works known as the Hebrew Bible.
450 BCE: Approximate year when Ezra the Scribe/Priest visits Jerusalem from Eastern portions of the Persian Empire and brings with him the "Scrolls of the Law" and teaches the people from them. This is the oldest reference to important religious writings in Jewish tradition (see Nehemiah 8).
333 BCE: Alexander the Great conquers the ancient Near East.
300–200 BCE: A large Jewish community develops in Alexandria, Egypt. Jewish religious writings begin to be translated into Greek, eventually producing the biblical Greek translations known as the Septuagint, which continue to expand until the first century BCE. Christians later use the Greek version for their Old Testament.
200–100 BCE: The oldest of the Dead Sea Scrolls is written (according to historians' best guess).
200–180 BCE: The book of Sirach (49:8–10) refers to "Twelve Prophets," suggesting an early collection of the 12 "minor" (that is, shorter) Prophets that are now part of the Hebrew Bible.
20 BCE–50 CE: Philo of Alexandria makes one of the earliest references to the three-part division of Hebrew Scriptures into Law, Prophets, and Writings/Poetry. Although specific books aren't listed, an agreed-upon list is clearly emerging.
4 BCE–around 32 CE: In Luke 11:48–51, Jesus may be implying that there's an emerging Hebrew "collection" of scriptures when he refers to martyrs from Abel to Zechariah, suggesting Genesis through 2 Chronicles.
70–90 CE: Rabbi Yochanon Ben Zakkai, an important first-century CE Jewish leader, gathers a group of teachers in Jamnia (on the coast of Palestine). They may have discussed approved Hebrew scriptures, but there's no indication that a list is settled at this time because debates continue among scholars in later Jewish writings.
70–90 CE: The ancient Jewish historian Josephus refers to the three-part division of the Hebrew Bible and refers to 22 books without listing them.
Around 100 CE: The book of 4 Ezra makes reference to 24 books of the Hebrew Bible without listing them.
Around 200 CE: The Jewish Talmud (Baba Bathra 14–15) finally provides a list of books, making it the earliest list of what emerges as the Old Testament for Protestants and the Hebrew Bible for Jews (same books, different order).
Dates that Impacted Formation of the Christian Old Testament
In the last two centuries before Jesus, Jewish writings translated into Greek (including Greek translations of the older Hebrew works not included in the Hebrew Bible) started to come together to form the Christian Bible, more specifically the Old Testament. These dates are important to the development of the Old Testament:
30–33 CE: Jesus quotes from many passages of Hebrew scripture but leaves his followers with no list for a "Bible."
40–60 CE: Saint Paul quotes from the Hebrew scriptures but doesn't discuss lists or a canon.
150–160 CE: Justin the Martyr refers to the Hebrew Bible as "scriptures" for Christians.
363 CE: The Council of Laodicea (59th Statement) restricts readings in the Church to the accepted books, but the 60th Statement that immediately follows, which consists of a list of books, is widely disputed as inauthentic (or added years later) and doesn't include Revelation.
367 CE: The Festal Letter of Athansius provides the first full list of Old and New Testament books for Christians and even lists books that were appreciated but not included as well as a few titles generally rejected. Most scholars agree that this is truly the first list in possession for the Christian canon of the Bible.
1546 CE: The Council of Trent of the Roman Catholic Church makes its list of the Old Testament official, and henceforth, Catholics reaffirm their use of the "Deutero-Canonical" books in their Old Testament.
1950 CE: The Holy Synod of the Greek Orthodox Church makes its decision about the Old Testament, including 2 Ezra and 3 Maccabees. It places 4 Maccabees in an appendix.
Important Dates for the Formation of the New Testament
When and how did Christians decide to add to their biblical canon with a new set of writings? This list shows the time and events that impacted Christians to develop the New Testament:
30–100 CE: The earliest New Testament works, Paul's Epistles, appear, probably pre-dating the writing of any of the Gospels. Paul never quotes a written work about Jesus.
95 CE: Clement of Rome refers to the "Words of Jesus" but doesn't quote writings.
90–130 CE: The Epistle of Barnabas refers to a teaching of Jesus by saying, "As it is written. . . ."
140–155 CE: Polycarp cites a letter of Paul by calling it "scripture."
150–160 CE: Justin the Martyr refers to a written Gospel and quotes from Luke.
170–around 180 CE: Irenaeus first refers to a "New Testament" and also refers to four Gospels, comparing them to the four directions (north, south, east, and west) and thus suggesting their completeness.
260–340 CE: The Christian historian Eusebius begins to enumerate books and create lists, but they're neither complete nor considered final.
334–336 CE: Constantine, the Roman ruler who converted to Christianity, commissions Bibles to be produced by hand, but these Bibles include writings (such as the Shepherd of Hermas and Didache) not accepted in later canons of the New Testament.
As early as 200 CE or perhaps as late as 350–375 CE: The Muratorian Fragment, considered by many to be proof of a Christian canon by 200 CE, is a document whose actual date is widely and hotly disputed. Many scholars date this document much later (some say after 350), but the document's list differs from the list that the Christian Church finally agreed upon.
367 CE: Athanasius writes a Festal Letter (a religious writing on the occasion of a festival) that contains the 27 books of the New Testament canon as it's known today. (He was also the first to use the word "canon" in reference to this list.) All historians agree that this is the oldest clear expression of a finalized New Testament canon, but they disagree about whether there are earlier indications of a canon.


Should You File Your Tax Return from the Cloud or on Your PC?
Using online tax preparation software to file your taxes is the new "normal". More and more people in the U.S. are taking advantage of do-it-yourself software to fill out and file their returns each year. The IRS reports that in 2012 more than 112 million taxpayers used the e-file service to submit a return.
If you are thinking about filing your return with an online tax service this year, you may want to consider the limitations of a desktop software program versus a cloud based program (provided and stored online). Using filing software over the cloud is virtually identical to using desktop software, however, using desktop software has a number of usage limitations when compared with cloud based software.
First with online tax software, there are never any operating system compatibility problems. You access your return from a web browser running on any web-enabled device. That can be a PC, laptop, tablet or phone and powered by an either Apple, Windows, Chrome or any other operating system. With a desktop based program you are limited to one device running a specific platform which it was designed for, unlike the cloud where you can work on your return from any web enabled device.
With cloud-based, online tax preparation, your return is automatically backed up on secure servers. With us, prior year returns are stored and accessible for your convenience at any time. If you use a desktop program and do not back up the return, you risk losing it if you have a hard drive or operating system failure.
Did you know you are responsible for downloading updates with most desktop preparation programs? If you are using a cloud based program, you never have to worry about having the latest version of the software or downloading updates during the tax season. Bugs are fixed and tax law updates are made automatically. You will always be accessing the latest version every time you log in.
Only you can judge if desktop or cloud-based tax software is best for you. If you decide to choose a cloud filing product this year, we hope you file your taxes with E-file.com.


Rating: 4 out of 5 with 421 votes.
This CSS/HTML Code of Black Flaming works on almost every website or web page on the internet that allows, CSS and HTML coding. Like forums, normal web page etc.
this doesnt make sense how do you make it your cursor?!?!?!


Across the globe, dementia affects around 45 million people – 850,000 of which are in the UK alone. With it being such a prominent illness, we believe that everyone should be aware of the true impact the condition has on an individual's life.
Dementia is the name given to a collection of symptoms that lead to an overall decline in brain health over a long period of time. These symptoms eventually lead to brain cell death and have a significant effect on the sufferer's daily life.
The 6 types of dementia are Alzheimer's disease, Lewy Body dementia, mixed dementia, frontotemporal dementia, vascular dementia, and Parkinson's disease. The most common type of dementia is Alzheimer's disease which affects 62% of dementia sufferers. Parkinson's disease and frontotemporal dementia only affect 4% of dementia sufferers and are much more difficult to diagnose.
The first step in getting a diagnosis is to recognise the signs in yourself or your loved ones. Once you've recognised these vital signs, it's important that you or your loved one visits a GP who can offer an official diagnosis.
Whilst at the doctor's office, blood tests will be conducted that will highlight any other issues that could be causing the symptoms instead of dementia. If the blood test results come back clear, the next step is undergoing cognitive testing and brain scans.
Cognitive testing involves taking things such as IQ tests and mirror tests to observe visual self-awareness and learning ability. Brain scans are required to determine if there have been any physical changes to the brain like a deterioration of tissue.
Upon completion of these tests, if the diagnosis is dementia, the doctor can prescribe a selection of medications that can slow down brain health decline. Although there is no cure for dementia, medication can make it much more manageable.
Our infographic walks you through the entire process of dealing with dementia whilst highlighting some shocking statistics. Check it out below and let us know what you think!


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Bob Vlach, Woodford Sun Staff
Food pantry distributes fresh produce to local seniors
Kentucky-grown produce was delivered to the Food Pantry for Woodford County on Tuesday morning. Senior citizens in the community living on fixed incomes received the fresh vegetables. The state's Farms to Food Banks program ensures tomatoes, corn, watermelons and other vegetables grown by Kentucky farmers are distributed to the hungry in communities across the state. "The legislature has taken a proactive bite against hunger and we've been able to pass some meaningful legislation in just the last three sessions, which really helps - not only here, but across Kentucky," said state Rep. James Kay. He and other state legislators allocate $600,000 a year to fund the Farms to Food Banks initiative, which provided the pallets of fresh produce delivered to the local food pantry on Tuesday. "At this time of the year, to get fresh produce, it's wonderful," said volunteer Bill Phelps, president of the Food Pantry for Woodford County's board of directors. He said about 108 senior households in the county are served through the food pantry's senior program on the first Tuesday of each month. When seniors arrived at the Food Pantry for Woodford County this past Tuesday, God's Pantry had delivered about 12,000 pounds of Farms to Food Banks produce. "In the summertime when we have access to those fresh crops and (we're) able to immediately get them to somebody in need - how cool is that?" said Mike Halligan, chief executive officer of God's Pantry in Lexington. "There's nothing better than a fresh ear of sweet corn or a tomato that you've cut into quarters, with a little bit of salt. There's just nothing better." Many of the seniors who received the fresh vegetables on Tuesday remember eating vegetables out of their gardens, said food pantry volunteer Peggy Carter Seal. She said local donations throughout the year ensure fresh vegetables are available to food-insecure families living in the community. In the next two to four weeks, the Food Pantry for Woodford County will receive a new freezer. God's Pantry Food Bank will deliver 45 freezers to Central and Eastern Kentucky communities as part of state Agriculture Commissioner Ryan Quarles's Hunger Initiative. The freezers extend the life of perishable food items donated to local food pantries, according to Halligan. He said being able to freeze protein-rich meats also supports nutritional balance in a person's diet. Agricultural lenders Farm Credit Mid-America and CoBank provided the Kentucky Department of Agriculture with the 18 cubic-foot freezers for distribution to local food banks, according to a state Department of Agriculture press release.

redpajama_set_name: RedPajamaCommonCrawl


There is a limited range of worming products available for worming donkeys on the UK market. Here is a list of those products currently licensed for donkey treatment and available from us.
As in the case of treating horses you must be competent to do so before administering animal medicines such as wormers to donkeys. The products selected for use should chosen on the same grounds as you would do so for other equines which means taking in all the factors involved and developing a worming strategy suitable to the environment and pertaining circumstances. Although the range of licensed products for donkeys is more limited than for the horse there is still a range which will enable you to plan over a longer period with out over reliance on any one chemical group whilst remembering that there are products in the above list that have different brand names but are in fact the same active ingredients and certain products will treat for a broader spectrum of parasites when used at higher doses. We are here to helpin fine tuning or organising any such plan.
Lungworms are white in colour and are between 6 and 10 cm in length.
The lifecycle of lungworms is different to other nematodes as adults settle in the lungs rather than the intestine. Eggs are laid then travel up the trachea, are swallowed and passed out in the faeces. Further development then takes place on the pasture, infective larvae are swallowed by horses or donkeys to further develop into egg laying adults.


Our business is committed to providing Colorado patients with safe, affordable and confidential access to quality medical cannabis. Our business pledges to uphold and defend Article XVIII, Section 14 of the Colorado Constitution, Colorado's Medical Marijuana Law. We sincerely believe that what is good for patients is good for business, and we will always put patients first.
If you are currently involved in the cannabis industry, thinking of starting a cannabis business, or support cannabis commerce, please consider becoming a member. Membership is free, and members are encouraged to join one of our volunteer committees, which are helping shape the future of the cannabis industry.


Video accounts for nearly 80% of all internet traffic. It can also boost email click-through rates by 200-300%, making it a powerful tool for expanding online reach.
At THE BLACK AND WHITE GROUP, we produce videos that engage viewers. We take the time to understand your goals and make a detailed plan based on your budget and timeframe.
We also write sharp, informative scripts that communicate your message with purpose and relevance. With your target audience firmly in mind, we express the personality and emotion of your brand, not by listing features, but by illustrating them. That way, customers can see how your product or service is right for them.
One of our many English and Arabic-speaking voiceover artists then brings the script to life. With care and passion, they read each word aloud, hitting the right tone and keeping a steady, consistent pace throughout.
From event coverage, product launches and video case studies to corporate and promo shoots, our videos resonate with customers. Produced by expert videographers and creative directors, they tell a unique story and leave a lasting impression.


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Q: Why would the LM Prediction function in R add a row to my output I am trying to use the predict function in R based of a basic linear model. My test set has 1459 values, but when I use the predict function it is creating 1460. I tried removing the NAs from the test set and even tried keeping them in, but do not know where this value is coming from.
Any help would be greatly appreciated.
Thanks!
MODEL <- lm(train$SalePrice ~ train$LotArea * train$GarageArea *
factor(train$FullBath) * train$YearBuilt * factor(train$OverallQual))

test_final <-read.csv("/Users/ERIC/Documents/HOUSING_PRICES/test.csv",
        header = TRUE)

    na.omit(test_final)

    prediction <- data.frame(predict(MODEL, test_final))

    Warning messages:
    1: 'newdata' had 1459 rows but variables found have 1460 rows
    2: In predict.lm(MODEL, test_final) :
    prediction from a rank-deficient fit may be misleading

Data via: https://www.kaggle.com/c/house-prices-advanced-regression-techniques/data

A: First, a note: you have to reassign the output of na.omit() to get rid of missing values.
See here:
df <- data.frame(x = c(1, 2, 3), y = c(0, 10, NA))
df
  x  y
1 1  0
2 2 10
3 3 NA
na.omit(df)
  x  y
1 1  0
2 2 10
df
  x  y
1 1  0
2 2 10
3 3 NA

As you can see, the last call to df showed you the initial version including the NAs. You will need to reassign using df <- na.omit(df).

The actual issue:
As pointed out by @42 in the comments, using formulas correctly will resolve this issue, i.e. you will not have this error message any longer. You will however have a different one. First, let me show you:
#read in the data
testdf <- read.csv("test.csv")
train <- read.csv("train.csv")

# run initial model, and run model as suggested by 42
model_original <- lm(train$SalePrice ~ train$LotArea * train$GarageArea * factor(train$FullBath) * train$YearBuilt * factor(train$OverallQual))

mod_42 <- lm(SalePrice ~ LotArea * GarageArea * factor(FullBath) * YearBuilt * factor(OverallQual), data = train)

Now, let us run predictions:
prediction <- data.frame(predict(model_original, testdf))
Warning messages:
1: 'newdata' had 1459 rows but variables found have 1460 rows
2: In predict.lm(model_original, testdf) :
  prediction from a rank-deficient fit may be misleading

This led to the same error as you have. Now, let us run the predictions using the second approach:
prediction <- data.frame(predict(mod_42, testdf))
Error in model.frame.default(Terms, newdata, na.action = na.action, xlev = object$xlevels) :
  factor factor(FullBath) has new levels 4

Note that the error message is different now, and points to a more interesting problem.

redpajama_set_name: RedPajamaStackExchange


The Before and After School Programs give your child the opportunity to grow and develop in an educational and fun setting. Programs are licensed by the state of New Jersey and offer a safe environment with professional staff to meet your child's needs. Programs run from September to June and follows the Pequannock, Pompton Lakes, Lincoln Park and Wanaque/Haskell Public School calendars.
The Before Care Program is offered at the following times for Pequannock, Wanaque/Haskell, and Lincoln Park students. There is no before care program for Pompton Lakes at this time.
Our program gives children the opportunity to spend time with friends in a safe, social, and supervised environment!
Download our registration forms below for further information!


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Alliance for Eating Disorders Awareness
West Palm Beach, FL, United States
AllianceforEatingDisorders.com
The Program is based at The Alliance. This Fellowship is focused on the care of individuals and their loved ones suffering from eating disorders. Individuals suffering from eating disorders represent a complex and heterogeneous population, one which challenges clinicians at all levels of ability. The Alliance provides an outpatient space for the treatment of adults, female and male, who present with various eating disorder behaviors, as well as other co-morbidity. Modalities of treatment offered at The Alliance include individual, couples, and family therapy, consultation, medication management, nutrition counseling, and a variety of group psychotherapies.
The Alliance will offer a 13 month Postdoctoral Fellowship Program. Three slots are available for each calendar year. These 40+ hour per week positions enable Fellows to accrue up to 2000 license-eligible hours of supervised practice during the course of their training. The experience allows the Fellow to develop a comfort level working with this population. Fellows function as valued members of a clinical team. As such, the Fellow operates with a significant degree of autonomy and responsibility, while maintaining close contact with staff from The Alliance.
Information regarding stipends and other benefits available upon request or by going to www.AllianceforEatingDisorders.com
To be eligible for the Postdoctoral Fellowship, applicants must have completed a doctoral program in clinical, educational or counseling psychology and a predoctoral internship with preference given to applicants from programs with APA accreditation. A doctorate from a developmental or school psychology program with predoctoral internship will be considered.
A letter of interest and a complete application to The Alliance for Eating Disorders Postdoctoral Fellowship Program must be received by December15, 2017 to be considered in the first pool of applicants. Interviews will be scheduled subsequently. The application may be found at www.AllianceforEatingDisorders.com.
Email me jobs from Alliance for Eating Disorders Awareness


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Polish prosecutors open investigation of head of top court
Warsaw's Soviet-era Palace of Culture and Science (Polish: Pałac Kultury i Nauki, also abbreviated PKiN) is the tallest building in Poland, and the sixth tallest building in the European Union. [ Jorge Láscar/Flickr]
Polish prosecutors said yesterday (18 August) they had begun investigating whether the head of the constitutional tribunal exceeded his authority by not allowing three judges chosen by the ruling parliamentary majority to rule on cases.
The inquiry marks another stage in the conflict between Poland's eurosceptic government and its top court. The conflict has already soured investor sentiment towards Poland, eastern Europe's biggest economy.
Poland's constitutional conundrum…explained
Like other European nations, Poland will remain a source of conflicting messages in years to come. But the EU has nothing to worry about – the democratic government in place can be removed in a peaceful manner next time people come to vote, writes Piotr Macej Kaczyński.
"This investigation is at a very early stage. We are gathering documents and are exchanging letters with the constitutional tribunal," said Ireneusz Kunert, a spokesman for the regional prosecutor's office in the city of Katowice.
The head of the constitutional court, Andrzej Rzeplinski, told state news agency PAP the investigation was as an "incompetent attempt" to encroach upon the independence of the judiciary.
Earlier this year, prosecutors in Warsaw declined to investigate whether the refusal of the government to publish some verdicts of the constitutional court was legal.
"Perhaps this investigation is a form of exerting pressure on the head of the tribunal, but I doubt it will impact actions of the court's head," said Piotr Kladoczny of the Helsinki Foundation for Human Rights.
Government spokesman Rafal Bochenek said that the decision of the prosecutor's office was independent.
Since winning an outright parliamentary majority last year, the ruling Law and Justice (PiS) party has passed several changes to the constitutional court's operational rules. The court ruled some of these change were illegal, but the government ignored the verdicts.
Parliament also scrapped last year the previous parliament's nominations for five of the court's 15 judges and put forward its own candidates, which were immediately sworn in by President Andrzej Duda, an ally of PiS.
The tribunal later ruled that three of the nominations of the previous party were legal and two illegal. PiS representatives said then that the process of the five new appointments had already been completed.
Critics say the government's changes to the tribunal had undermined democratic standards and are part of a broader push to seize more control over state institutions, charges denied by PiS.
EU formally warns Poland in rule-of-law row
The EU today (1 June) formally warned Poland that it should find a solution to roll back Warsaw's overhaul of the top Polish court, which critics say endangers its independence.
Poland shrugs off EU warning
Poland downplayed the EU's unprecedented warning on Thursday (2 June) to the country's right-wing government to respect the rule of law, or face punitive measures. EURACTIV Poland reports.
democratic deficit
Rule of Law Mechanism
6Poland, Germany get largest slices of Just Transition Fund
9European Parliament calls on member states to act on Poland and Hungary
10Athens smarting after exclusion from German-hosted Libya conference
3 responses to "Polish prosecutors open investigation of head of top court"
Thinker says:
Bravo Poland. This is right way to get rid of liberal=communist judge.
gruenebaum says:
Sure. Nothing is as bad as being liberal. I would, however, suggest that Poland continues on its path to autocratic rule outside the EU.
Ivan Belostenko says:
You forgot to mention one crucial point. It was Marian Kowalski (recent Polish Presidential candidate) that submitted the complaint. That's all it took. But PiS and others have been dragging their feet about this issues for months. Give credit where credit is due.


Rivals seem to be working hard to deem all of Ferrari's 2018 F1 car illegal!
First, it was Ferrari's halo-mounted mirrors. Then, it was their engine – which is still being scrutinised. Now, Red Bull Racing believe that Ferrari's DRS is illegal. How soon before rivals try and deem much of Ferrari's 2018 F1 car as illegal?
In Ferrari's case, it seems that their past reputation precedes them. The Italian team has often bent, broken and twisted the rule book to achieve glory and success in Formula 1. But then again, which teams haven't? In Formula 1, we have often seen in the past that the rule breaker is often a few steps ahead of the rule makers!
However, in Ferrari's case, their innovations almost always raise an eyebrow and I think it is a bit unfortunate. I don't think we question Mercedes and Red Bull Racing as much, but then again, there is a past reputation that drives our judgements when it comes to Ferrari. It could also be the media bias.
The Inside Line F1 Podcast, a top-rated podcast on iTunes, audioBoom and the BookMyShow Jukebox, is hosted every week by Mithila Mehta and Kunal Shah. This podcast offers a humourous view on the sport and business of Formula 1.


When Tae Cho proposed to his girlfriend Lindsey Crouch on a Florida beach, he thought the moment would be lost forever.
But not only did a kindhearted stranger photograph the romantic proposal, she posted the pictures on Facebook in a bid to find the couple - and it worked.
Now the Knoxville duo have Heather Swanner's perfect shots, along with a handful of grainy smartphone camera images taken by family members.
'I got a call yesterday evening and my friend Marisha was like, you will never believe what I'm seeing on Facebook,' Cho, 28, told News 5.
Swanner, a professional snapper based in Alabama, was photographing a family on a beach in Seaside, Florida, several weeks ago when she spotted the proposal in action.
Swanner said she noticed the couple's family hiding nearby with cameras.
Fearing she would get caught up in an imminent thunderstorm, Swanner left to finish her shoot without passing on her details to the couple.
But after sorting the proofs three days later, she decided to share the photos on her business' Facebook page to find the couple.
'When I saw them I realized they (the couple) really would probably want to have them,' Swanner told News 5.
The post was shared more than 300 times and, within a few hours, the couple she photographed got in touch with her.
'I post things all the time, but I think it takes something that tugs at people's heart strings to get them to share it,' Swanner said.
The couple, who plan to wed on September 27, said they were overwhelmed to see Swanner's pictures.
Crouch said she had seen Swanner taking the photos, but didn't have time to approach her.
'We saw Heather taking pictures, but in the excitement of everything we were unable to get her contact info,' Crouch said.
She said family members, including her mother, were too far away to capture anything but a few distant shots.
'It still is crazy to me that a photographer in Birmingham who happened to capture my engagement put a post online,' Crouch said.
Swanner gave the couple the photos as a wedding gift.


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NYPD Tracks Down Missing Teen Using Video Games
Offbeat 12:41 PM PDT, March 29, 2019 - JOHANNA LI
12:41 PM PDT, March 29, 2019 - JOHANNA LI
Many parents wish their kids would get off the computer, but it may all be thanks to his video gaming habits that this New York City teen is now home safe and sound.
A 15-year-old believed to have run away from his family's Upper East Side home was successfully reached through Discord, an online chat room geared toward gamers.
"I was there when he got back," said 25-year-old NYPD Officer Gary Strebel. "The parents were very happy to see him."
Strebel told WCBS it all started Saturday night, when he received a 911 call about the boy leaving his home without telling his parents where he was going.
The boy had apparently run away before, and officers went to check on places he normally goes, but when he didn't turn up, officers decided to check his computer at home.
"I noticed that his computer was open," Strebel said. "This app was open on his screen, and it's basically once you're logged in, it looks like a chat room. So there's different names different conversations open and I could see that he was chatting back and forth with some friends."
Strebel grew up loving video games, and when he saw it might help him in his career, he sprung to action with his unique skills. He quickly logged into his own account, sent the teen a friend request and began chatting with the him remotely.
"You sure don't sound like a police officer," the teen wrote.
Strebel replied, "[Because] I'm a normal guy. I play League of Legends and Fortnite and I'm a cop and I want you to come home or tell me where you are."
"OK, I'll take your word for it and come back," the teen wrote.
Strebel said he never anticipated his online presence would help a teen get home safely but offered a recommendation to other parents: "Awareness is key, so just being aware everybody uses social media and just keeping an eye on what they're doing on social media."
Police Get Called to a Reported Kidnapping, Find Out It's Just a Music Video
Woman Who Calls Police for Help Winds Up Getting Arrested
Suspect Named in 1973 Cold Case Killing of Young Couple After Police Use Genealogy Website
Courageous Teen Called Cops to Report Arizona 'House of Horrors' Mom


text:
Q: How to get the contents of the first cell of a row when double clicked on any column of a row in C# DataGrid I want to get the contents of the first cell of any row when any cell in a row is double clicked. (Example if I click on cell[row1, column2] or cell[row1, column3] in both cases I want to get the contents of the cell[row1, column1]).
With the code I have written I get the contents of the cell that is double clicked.
In my code var cellValue is giving me the contents of the cell.  So, I want to achieve the contents of the cell[row r, column1] inside var cellValue and private List<DataGrid> m_AllDgTag = new List<DataGrid>();
My Code:
private void DgCM_MouseDoubleClick(object sender, MouseButtonEventArgs e)
{
    int currentPnl = 0;
    if (m_AllDgTag.Count > 1)
    {
       currentPnl = m_CurrentFDS;
    }
    var cellInfo = m_AllDgTag[currentPnl].CurrentCell;

    if (cellInfo != null && m_CurrentStep != null)
    {
       var column = cellInfo.Column as DataGridBoundColumn;

       int cellColIndex = cellInfo.Column.DisplayIndex;

       if (column != null)
       {

           var element = new FrameworkElement() { DataContext = cellInfo.Item };
           BindingOperations.SetBinding(element, FrameworkElement.TagProperty,
               column.Binding);
           var cellValue = element.Tag;

          ...
       }
    }
}

I am attaching the image of the Item Array. I am able to get the data of the row inside 'var rowinfo'. From here i want to get the data of the column [0]. So in this case i want to get the value for example column[0] value: F21B1C001.enter image description here

A: Hasan, after your comment i understand that your code is a WPF app.
I create a sample in WPF
this is the XAML of the grid, the key of the solution is the

DataGrid.Resources Style TargetType="DataGridRow"

<Grid>
    <DataGrid HorizontalAlignment="Left"
              Height="203"
              Margin="175,126,0,0"
              DataContext="{Binding RelativeSource={RelativeSource AncestorType=Window}}"
              ItemsSource="{ Binding Persons }"
              VerticalAlignment="Top"
              Width="378" >
        <DataGrid.Resources>
            <Style TargetType="DataGridRow">
                <EventSetter Event="MouseDoubleClick" Handler="Row_DoubleClick"/>
            </Style>
        </DataGrid.Resources>
        <DataGrid.Columns>
            <DataGridTextColumn Header="Name" Binding="{Binding Name}"/>
            <DataGridTextColumn Header="LastName" Binding="{Binding LastName}"/>
            <DataGridTextColumn Header="Age" Binding="{Binding Age}"/>
        </DataGrid.Columns>
    </DataGrid>
</Grid>

this is the code behind
public partial class MainWindow : Window
{
    public MainWindow()
    {
        InitializeComponent();
    }

    private void Row_DoubleClick(object sender, MouseButtonEventArgs e)
    {
        var dbClickedRow = (DataGridRow)sender;
        MessageBox.Show(((Person)dbClickedRow.DataContext).Name);
    }

    public List<Person> Persons
    {
        get
        {
            return new List<Person>
            {
                new Person{ Name = "Gustavo", LastName = "Oliveira", Age = 35 },
                new Person{ Name = "Another", LastName = "Person", Age = 23 },
                new Person{ Name = "Neymar", LastName = "Junior", Age = 28 },
            };
        }
    }
}

public class Person
{
    public string Name { get; set; }
    public string LastName { get; set; }
    public int Age { get; set; }
}

A: I found the solution to the problem. If we use this piece of code we will get the value of column [0] of any row clicked.
var cellValue = ((System.Data.DataRowView)cellInfo.Item).Row.ItemArray[0];
Thank you for the help @Gustavo Oliveira


(2011; staged digital photography white fabric in forest; C-print on alu Dibond; variable in size, max. 180 x 120 cm) featured in the CreArt groupshow 2014 curated by Miguel Amado, João Laia and Rosa Leó.
Das Raster, angewandt bei Entwurf und Konstruktion physischer sowie virtueller Räume, sollte sich mit der unregelmäßigen Topografie des Waldes verbinden.


On this course, you'll learn a range of dramatic writing techniques for creating a one act play.
You'll leave this course with a one act play completed (or near completion).
Tina was shortlisted last year for the BBC Writersroom 10, leading to her be selected for the Holby City Shadow Scheme.
Tina previously ran her own Drama School for over ten years, and has taught creative writing in a variety of disciplines.
She has an MA in TV Scriptwriting (with distinction).
The fee for this course is £425.


Software development is one of the cornerstones of TechDo GmbH.
With our highly qualified team of application developers and programmers, we create future-oriented, functional and innovative solutions of all types,for and with our clients.
Individual developments always particularly show their strength where existing company and business processes cannot be mapped by standard software solutions at all or are unassisted. Individual developments furthermore convince by virtue of high quality, great flexibility, cost-effectiveness and speed. All of which are normally important and/or essential requirements for any company to attain an identity and satisfy a specific need for differentiation. We will support you in the creation of custom-fit solutions for your process-relevant application areas – from concept consultancy via specification creation, through to the finished development. The subsequent software maintenance will then safeguard your individual development.
But our staff will naturally also support our clients in error analysis, solution finding, implementation, further development and roll-out.
The following list provides an overview of the technologies, methods and tools successfully used by us in our company and projects, in alphabetical order.


text:
Q: Postgres Hot Standby and Long Running Queries On Slave Question: Can you have long running queries (30s+) running while having WAL updates applied on the slave (the slave role is as a Reporting DB Server) in a Hot Standby mode? The way it's working now is, either you set the params below to kill long running queries so WAL updates can be applied, or delay the WAL updates indefinitely until no queries are running to apply them. Can we have both? Long running queries and WAL updates being applied at the same time?
Case Implementation: We are currently using Hot Standby mode to sync any changes from one master to one slave. The slave role is as a reporting db server with queries constantly and concurrently running (some in ms, some in seconds,
some in minutes.) It would be very rare to have a gap of no active queries running on the slave.
We have adjusted these two params to allow long queries on the hot standby:
max_standby_archive_delay = -1  # max delay before canceling queries
max_standby_streaming_delay = -1  # max delay before canceling queries

And looking at an archived mail question similar to ours in a postgres mailing list:
http://www.postgresql.org/message-id/AANLkTinLg+bpzcjzdndsnGGNFC=D1OsVh+hKb85A-s=n@mail.gmail.com
I understand the concept of preventing WAL updates being applied to
slaves while queries are running. However, I thought with the use of MVCC,
an active query on the slave (long running, 30 seconds+) can run reading
from one version/snapshot, while the WAL update is being applied, so
subsequent queries will get the WAL updates when that WAL transaction is
committed. I haven't fully digested the MVCC model used in PostgreSQL yet
https://devcenter.heroku.com/articles/postgresql-concurrency, so this is
just my assumption -- that even if a table is dropped / truncated during a
WAL update, the current running query should still work as it's using a
version/snapshot of the table(s) it's querying?
Summary: Is there anyway (even with a third party extension) we can sync slaves
from a master and have those updates from the master be applied to the
slave right away while letting queries of any execution time continue to
run till they complete on the standby/slave? If Hot Standby can't do that,
what would you recommend for this situation? Our scenario is that we are
hitting postgres with queries constantly and concurrently running (some in
ms, some in seconds, some in minutes,) leaving almost no time for a WAL
update to be applied. We have used Bucardo, but that wouldn't be a good
choice in this scenario, as we over 200+ tables that would need to be
synced, including views as well 40+ other databases aside from our main
database.
Any help would be greatly appreciated.
Thank you!

A: Thanks Guillaume for your answer, but luckily, starting in PostgreSQL 9.1, PostgreSQL has the hot_standby_feedback option (you set this on the standby server in postgresql.conf) which wont kill long running queries and will allow for WAL updates to the standby servers. Credit for this answer goes to three people on the PostgreSQL mail list (Raja/Albe/Scott) who helped me on this in that mailing thread. Hopefully this could be helpful to someone searching for this answer on stackoverflow. The email thread can be found here:
http://www.postgresql.org/message-id/D274E3C1.1113E8%awilliams@dresourcesgroup.com
http://www.postgresql.org/docs/9.1/static/hot-standby.html
Excerpt:

Remedial possibilities exist if the number of standby-query cancellations is found to be unacceptable. The first option is to set the parameter hot_standby_feedback, which prevents VACUUM from removing recently-dead rows and so cleanup conflicts do not occur. If you do this, you should note that this will delay cleanup of dead rows on the primary, which may result in undesirable table bloat. However, the cleanup situation will be no worse than if the standby queries were running directly on the primary server, and you are still getting the benefit of off-loading execution onto the standby. max_standby_archive_delay must be kept large in this case, because delayed WAL files might already contain entries that conflict with the desired standby queries.

Solution Implementation:
Here's what your postgresql.conf should be configured to on the standby server:
max_standby_archive_delay = -1
max_standby_streaming_delay = -1
hot_standby_feedback = on

A: PostgreSQL is a very good database engine in the sense that most queries won't lock the tables. Internally, it has a sort of revision system per row in your table, which means it can continue to write the WAL during your other reading transactions.
The Logs are also very resistant to delay, and unless you have a massive traffic, it will always catch up at some point.
Just make sure that you don't use Lock commands, and you'll be fine.


text:
Men's Scores & Fixtures
Women's Scores & Fixtures
England Cricket Team Home
Ashes: Trevor Bayliss to step down as England coach in 2019
By Stephan Shemilt
BBC Sport in Sydney
Why is England coach Trevor Bayliss stepping down?
Trevor Bayliss will step down as England coach when his contract expires at the end of the 2019 Ashes.
The 55-year-old, who was appointed in 2015, has just seen his side beaten 4-0 in Australia, but told England director of cricket Andrew Strauss of his plans a year ago.
"I'm contracted to September 2019 and that will see me out," the Australian told BBC Sport.
"I've always felt that it's time for a change around that four-year mark."
He added: "A new voice and a different approach reinvigorates things."
Bayliss led England to a home Ashes triumph in his first summer in charge and later presided over a Test series win in South Africa and a run to the final of the 2016 World Twenty20.
'He got married wearing a pink jacket' - who is the real Trevor Bayliss?
Headbutts, heroes & leaf blowers - Ashes winners and losers
With the World Cup on home soil in 2019, England's steady progress in the 50-over game has been such that a semi-final defeat in the 2017 Champions Trophy was seen as a disappointment.
However, the team's recent Test results have been mixed.
In 38 matches under Bayliss, they have lost 18 and won 15. The tour of Australia extended their winless run in away Tests to 11 matches.
England's next assignment in Test cricket is two matches in New Zealand in March.
The squad for that trip will be announced on Wednesday at 22:00 GMT - 24 hours later than planned as captain Joe Root recovers from the severe dehydration he suffered during the final Ashes Test.
Australia coach Darren Lehmann will also leave his post after the 2019 Ashes in the UK.
In a wide-ranging interview with the BBC, Bayliss also said:
He can't see any "big changes" following the latest Ashes defeat in Australia.
Batsmen Mark Stoneman and James Vince deserve more chances in the Test side.
The off-field problems of the Ashes tour have made this tour one the toughest of his career.
The "penny has dropped" for the players about their off-field behaviour.
England may have to risk losing at home in order to improve away.
Man-eating moths & Boycott's laundry: TMS' funniest Ashes moments
'Stoneman and Vince showed potential'
Of the inexperienced members of England's batting line-up in Australia, Dawid Malan scored a maiden Test century and ended the series as England's leading runscorer.
Stoneman and Vince both made two half-centuries but ended with averages in the mid-20s. Stoneman did not pass 24 in his final four innings, while Vince was often dismissed in the same manner - an edge to the wicketkeeper or slips.
"The way Stoneman and Vince played, they do deserve a bit more of a chance," said Bayliss. "They were playing against one of the best attacks in the world in their home conditions and showed the potential they have.
"They are aware that it's about performance and scoring enough runs. If, over a period of time, that doesn't happen and you have to look for someone else, that is the way of the game."
As for the rest of the side that could line up for the first Test in Auckland, Bayliss does not expect it to be dissimilar from the one beaten by an innings in the final Ashes Test.
England are still awaiting news on Ben Stokes after the all-rounder was arrested for an altercation outside a Bristol nightclub in September.
Pace bowlers Craig Overton, Mark Wood, Chris Woakes and Toby Roland-Jones are all looking to return to fitness, while leg-spinner Mason Crane is set to travel after making his debut in Sydney.
Batsman Gary Ballance, who did not play a Test on the Ashes tour, could miss out, with players such as Liam Livingstone, Joe Clarke or Dan Lawrence potential candidates for a first senior tour.
"I can't see any big changes," said Bayliss. "We've known for a couple of years that we have been three or four performing players short of a very, very good team.
"Probably five or six positions in the squad will be discussed."
What really happened between Bancroft & Bairstow?
'Off-field issues made it a challenge'
In Australia, England were not only hampered by the absence of Stokes but, in the early part of the tour, had to deal with several off-field issues.
Wicketkeeper Jonny Bairstow was accused of 'headbutting' Australia's Cameron Bancroft, while Lions batsman Ben Duckett poured a drink over senior bowler James Anderson. Both incidents occurred in the same Perth bar.
When news of Duckett's indiscretion emerged during a tour match in Perth, an irate Bayliss suggested some players would start paying with their place in the side if behaviour did not change.
He has since seen an improvement, but still believes the furore around the off-field problems created one of the most difficult tours of his career.
"Some of the off-field stuff at the start of the tour was as tough as I've experienced," said the former Sri Lanka coach.
"You could do without it, but I think the penny has finally dropped with the boys that we are in a different environment nowadays. Going forward I don't foresee any problems there.
"It certainly made it a challenge earlier in the tour, but you look back now and, apart from that and the result, it's been an enjoyable Ashes contest. Sometimes, even on the losing side, it's enjoyable to be involved in."
Australia have lost only one home Ashes series since 1986-87
England's winless run away from home is part of a longer-term problem, with just one victorious series abroad since 2012.
In the same time period, they have been beaten only once in the UK.
In order to reverse their travelling fortunes, perhaps by nurturing a spinner or bowler of high pace, Bayliss says England might have to gamble with their home form.
"That could be a risk," he said. "If that was to occur and we're not as successful as we'd like to be because we're blooding some young players, we have to take that on the chin and hopefully everyone realises that we're heading in a certain direction.
"Hopefully if you have those guys around the squad, they force their way in. That would be the best scenario.
"One of things you get from new players in a squad is a youthful intensity that can up the interest of everyone.
"It might be, home or away, you chop and change a little bit. You might blood a young fast bowler somewhere like South Africa, or a young spinner in the subcontinent."
Remorseless Australia press on against England - in-play clips, TMS & text
Read more on Remorseless Australia press on against England - in-play clips, TMS & text
Ponting joins Australia T20 staff
Read more on Ricky Ponting: Australia name former captain as Twenty20 assistant coach
'England can't brush defeat under carpet'
Read more on Ashes: England's Ashes defeat cannot be brushed under carpet - Jonathan Agnew
The winners and losers from the Ashes
Read more on Ashes: The winners and losers from the 2017-18 series
Ashes tour has not been disastrous - Anderson
Read more on Ashes tour has not been disastrous - Anderson
Ashes victory in England on Smith's 'bucket list'
Read more on Ashes victory in England on Smith's 'bucket list'
Australia crush England to seal 4-0 win
Read more on Ashes: Australia beat England by innings & 123 runs to seal 4-0 series win


Hora, Matthew T., et al. "Exploring the Situated and Cultural Aspects of Communication in the Professions: Implications for Teaching, Student Employability, and Equity in Higher Education." WCER Working Paper 11. (2018): 1-37. Web.


IES that is Indian Engineering Services or Engineering Services Examination (ESE) is conducted every year by Union Public Service Commission. Four core engineering branches are eligible to appear in this exam. You may check more detail about IES Exam here. Since the success ratio of ESE is very low so to crack this exam candidates should have proper strategy. Here we are sharing you those right strategy to crack Indian Engineering Services Exam. In this post we will discuss on both objective and conventional paper preparation strategy. Along with preparation strategy you will also know here about steps to solve conventional problem in examination hall.
This exam pattern is common for all 4 branches.
1. Prepare all topics from all subjects.
2. Focus on theoretical and formula based questions.
3. No need to solve lengthy numerical problems of previous GATE papers.
4. Main focus will be on IES previous and IAS previous questions.
5. Make Subject priority list for Objective and Conventional paper on the basis of number of question asked in previous papers.
6. Since IES Syllabus is common for both objective and conventional paper, Start preparing both objective and subjective paper side by side.
7. Cover all subject according to IES SYLLABUS.
8. Don't start two subject at a time. Try to focus on single subject at a time.
9. Must take a note of key points, silly mistakes and mark those few questions whose practice refreshes your concept.
10. Do objective paper practice in time bound manner.
2. During Preparation Always do conventional after solving objective questions of that topics.
3. During study of each topic you must focus on derivation of formulae which helps a lot in solving conventional problem.
4. Study all topic/subject of conventional paper on the basis of priority list. Means focus more on topics/subjects whose weightage are more.
5. Must practice on style of presentation for conventional problem.
Step-1: Read the instruction carefully which is in the question paper and be clear about how many questions you have to answer.
Step-3: Start answering with easiest one. But remember all parts of the question should be answer in one place in sequential manner.
If question no 3 has three parts (a), (b) and (c). You find 3(c) is easy one and want to answer then first mark 3(a), 3(b) and 3(c) with different pages on your answer sheet assuming that you need that much space to answer that part of the question. Now you are free to answer 3(c) first that you find easiest in the paper.
Step-4: After 2.45 hr. write P.T.O In the middle of all blank pages which you have left earlier to answer but unable to do.
Step-5: For 5 to 10 marks question you don't need the formula derivation. Do the formula derivation only if a question is of more than 10 marks.
Step-6: Write the meaning of all the symbols used. e.g Mass (m) = 27 kg.
Velocity (v) = 15 m/s etc.
Step-7: Remember there is part marking if you write something they will give you some marks so Write whatever you know about the question.
For IES/ESE Previous Papers of All Branches Visit Here.
Please Rate, Like & Share this Article.


A state legislator wants the state and federal governments to look into plans to dump 2,250 tons of contaminated soil from the former 'Aiea Sugar Mill at the Waimanalo Gulch Sanitary Landfill in Leeward O'ahu.
Sen. Colleen Hanabusa, D-21st (Kalaeloa, Makaha) has requested a formal investigation by the state Department of Health as to whether the transport and intended use of the contaminated soil meet environmental standards. She also wants the U.S. Environmental Protection Agency to look into the case.
Hanabusa said plans call for lead-contaminated soil to be used as ground cover for the landfill, which is near Kahe Point.
Health Director Bruce Anderson said the department made no ruling on the dumping of contaminated soil into the landfill.
However, he said the landfill is one of only two places on the island where the soil could be legally dumped.
Anderson said the soil needs to be removed because there are plans to build a daycare center on the old mill property.
Le Jardin Academy will hold opening ceremonies at 10 a.m. tomorrow for its newly completed temporary high school facility, the Harold K.L. Castle Building.
The ceremonies also will kick off the first day of school for the 50 freshmen of the class of 2006, the school's first high school students.
The school is at 917 Kalaniana'ole Highway, Kailua.
The Hawai'i Children's Discovery Center will host a "family pizza night" today.
The center, in the Kaka'ako Waterfront Park, will be open for special hours from 10 a.m to 7 p.m. today, and pizza will be served from 5 to 7 p.m. Admission is $6.75 for children ages 2 to 17 and $8 for adults.
The Children's Discovery Center is a private, nonprofit museum that includes exhibits for children. For information, call 524-5437.
O'ahu motorists are being advised of lane closures on the Pali, Kamehameha and Kalaniana'ole highways beginning tomorrow.
The Kailua-bound right lane of Pali Highway from the emergency truck ramp to just beyond Castle Junction will be closed from 8:30 a.m. to 3 p.m. through Friday to allow workers to install new telephone duct lines. The state also will close the left-turn lane from Kamehameha Highway to Kalaniana'ole Highway in Kailua during this same period.
In East Honolulu, one kokohead-bound lane of Kalaniana'ole Highway will be closed between 'Ainakoa Avenue and West Hind Drive from 8:30 a.m. to 3 p.m. tomorrow through Friday for resurfacing work.
Motorists are advised to anticipate delays in the construction areas or take alternate routes.
Public hearings to review the city Department of Planning and Permitting's draft Primary Urban Center Development Plan will be held at 7 p.m. Tuesday at Moanalua Middle School and Thursday at McCoy Pavilion at Ala Moana Beach Park.
The focus of the meetings will be to present the planning framework for communities from Pearl City to Kahala through the year 2025 using concepts developed during community workshops last year.
The plan will be used as a guide to zoning, land use and public investment in central Honolulu that is consistent with the city's General Plan.
The development plan's vision for Honolulu includes protecting and enhancing the natural, cultural and scenic resources; creating livable neighborhoods with business districts, parks, plazas and walkable streets; offering in-town housing choices for people of all ages and incomes; recognizing that Honolulu is the leading city and travel destination in the Pacific; and building a balanced transportation system.
The Primary Urban Center Development Plan is one of eight regional plans on O'ahu mandated by the City Charter.


text:
May 11, 2010 - SNPWatch
SNPwatch: Large Study Identifies Two More Genetic Variants Associated with Alzheimer's Disease
Understanding Alzheimer's disease, the most common cause of dementia in people 65 years and older, is of the utmost importance as the population of the United States (and many other nations) becomes increasingly older. Currently more than five million Americans are thought to have the disease, but by the year 2050 that number is estimated to reach 14 million unless a cure or prevention method is developed.
Until very recently, mutations in only one gene–APOE–had been conclusively associated with the more common late-onset form of Alzheimer's (there are others associated with early-onset disease). In September 2009 two groups studying large numbers of people identified variants in three new genes that had small effects on the disease.
Now researchers have pulled together the results of several studies and found variations in two more genes associated with increased risk. The scientists, whose results appear online today in the Journal of the American Medical Association, suggest that these variants may be important for unraveling the underlying biology of Alzheimer's, which will be essential in the quest to find new methods of treatment.
Researchers from the CHARGE, GERAD1 and EADI1 Alzheimer's research consortia combined data from more than 35,000 people (more than 8,000 with Alzheimer's) with European ancestry. They found a variant near the BIN1 gene was associated with 1.13 times increased odds of Alzheimer's. They also found another variant near the EXOC3L2/BLOC1S3/MARK4 genes was associated with 1.18 times increased odds of Alzheimer's.
The BIN1 gene encodes a protein that is highly expressed in the brain and known to be important in processes that are disrupted by the plaques that form in the brains of people with Alzheimer's. Two of the genes near , BLOC1S3 and MARK4, encode brain proteins that are also involved in processes that are known to be disrupted in Alzheimer's disease. The MARK4 protein in particular is interesting because it interacts with tau, the protein responsible for the tangles seen in the brains of people with Alzheimer's .
Combined analysis of all of individuals studied also provided support for previously identified associations in the CLU and PICALM genes.
Compared to a model that uses only APOE status, age and sex, adding in a person's information for the replicated SNPs in the CLU and PICALM genes did not substantially improve risk prediction. The researchers note that in light of the small effect sizes of these SNPs, this is not unexpected.
"The value of these associations may lie in the insights they could provide for research into the pathophysiological mechanisms of AD [Alzheimer's disease]," the authors write.
In an accompanying JAMA editorial, Nancy Pedersen of the Karolinska Institute in Stockholm, Sweden, points out that it's not surprising that the new variants don't add much to risk prediction, writing that this finding "only verifies the notion that AD is a polygenic disorder; i.e., that potentially tens of thousands of risk alleles, each with a small effect, are important for liability to disease. What is remarkable is that the single gene APOE is as important as it is for this complex disorder."
Pedersen's opinion is that researchers should forgo further pursuit of new genetic variants or replications of already identified SNPs, and instead turn their attention to the study of environmental risk and protective factors for Alzheimer's disease. She notes that in identical twins, there is at most a 61% chance that both twins will end up with the disease, indicating that non-genetic factors play an important role. Further, she points outs that Alzheimer's disease that sets in very late in life has been shown to be less heritable, suggesting that environment gets more and more important as people age.
Pedersen ends by noting that right now, the most important thing doctors can do is encourage people to make lifestyle changes, especially those that improve cardiovascular health, that may reduce the risk of dementia or at least postpone it.
SNPwatch gives you the latest news about research linking various traits and conditions to individual genetic variations. These studies are exciting because they offer a glimpse into how genetics may affect our bodies and health; but in most cases, more work is needed before this research can provide information of value to individuals. For that reason it is important to remember that like all information we provide, the studies we describe in SNPwatch are for research and educational purposes only. SNPwatch is not intended to be a substitute for professional medical advice; you should always seek the advice of your physician or other appropriate healthcare professional with any questions you may have regarding diagnosis, cure, treatment or prevention of any disease or other medical condition.
CategoriesSNPWatch
TagsAlzheimer's diseaseAPOEJAMAtau
SNPWatch
Pregnancy and MTHFR
The Genetics of Adolescent Growth Spurts
A tale of two fingers
A Song Draws Focus on Osteosarcoma Research


What Is Non Surgical Body Contouring?
Home > Body Contouring > What Is Non Surgical Body Contouring?
There is no true alternative or procedure, surgical or non-surgical, that can replace a healthy lifestyle. Medical procedures can, however, help nudge us toward healthy habits through motivation and kickstarting results.
What Is Non-Invasive Fat Reduction / Body Contouring?
Body contouring is a new and developing group of technologies that allow for the reduction of body fat with minimal risk, reduced cost and negligible recovery time compared to surgical options.
None of these devices rivals the results of cosmetic surgery, but patients may not want the associated recovery time, surgical scars, and waiting months to see their final results. Body contouring was designed for people who don't want to undergo surgery and are willing to accept less immediate dramatic changes.
Non-invasive fat reduction is appropriate for individuals who can't eliminate stubborn body fat despite diet and training.
There are five main technologies used: freezing fat (CoolSculpting®), ultrasound, radiofrequency, pulsed electromagnetic fields, lasers and combinations of these. The most effective has been a combination of both ultrasound as well as radiofrequency to reduce areas of unwanted fat.
A device from Alma Lasers called Accent Ultra™ offers both ultrasound as well as radiofrequency alone or in combination and the result is called shear-wave ultrasound body contouring, which is more effective at disrupting fat cell membranes leading to gradual breakdown and the release of stored fat.
Body contouring sessions usually last around an hour depending on the amount of fat, the treatment areas, and anything from a single treatment session to 6 or more may be necessary.
The shear-wave ultrasound body contouring is designed to target the fat cells without damaging the skin and other tissue. Gradually, in a matter of few weeks destroyed fat cells are then disposed of the body through the lymphatic systems.
The remaining fat cells can replace the dead ones so after the procedure to keep the results; individuals need to maintain a healthy lifestyle post procedure.


text:
The Plain Dealer is a newspaper in Cleveland, Ohio.  The term "Plain Dealer" and variations may also refer to:

other newspapers
Alturas Plaindealer, newspaper in Alturas, California, from the mid-nineteenth century to 1952
The Plain Dealer (Kadina), newspaper in Kadina, South Australia (1894–1926)
Cresco Times Plain Dealer, newspaper in Cresco, Iowa
Ouray County Plaindealer, newspaper in Ouray, Colorado, established in 1877
Souris Plaindealer, newspaper in Souris, Manitoba (1892-2020)
Topeka Plaindealer, newspaper in Topeka, Kansas, serving the African American community (1899-1958)
Wabash Plain Dealer, newspaper in Wabash, Indiana, established in 1859

theatre
The Plain Dealer (play), theatrical play first performed in 1676

See also
Plain Dealer Pavilion

redpajama_set_name: RedPajamaWikipedia


text:
Professor John Atack
Director, Medicines Discovery Institute
atackj@cardiff.ac.uk
Main Building, Park Place, Cardiff, CF10 3AT
I am a molecular pharmacologist with over 25 years of drug discovery experience, primarily in the field of neuroscience. During this time, I have contributed to the earliest stages of drug discovery (target identification and target validation) all the way through to Phase 1 and Phase 2 clinical trials.
I have worked on a number of different types of drug targets (enzymes, G-protein-coupled receptors and ion channels) covering a range of neurodegenerative diseases (e.g. Alzheimer's, Huntington's and Parkinson's diseases) and psychiatric disorders (bipolar disorder, schizophrenia, generalised anxiety disorder, depression). I am particularly interested in the translational aspects of preclinical drug discovery which give confidence that a particular drug candidate can engage with the target and produce a functional readout in man.
My favourite drug and mechanism of action? Well, that would have to be diazepam and the GABAA receptor ... Or maybe it is ketamine and the NMDA receptor … Or lithium and however that works in bipolar disorder … Not to mention donepezil, so I won't.
Following a PhD in neurochemical pathology in the Department of Pathology in Newcastle General Hospital, I worked for 5 years (1984-89) in the Laboratory of Neuroscience in the National Institute on Aging on the National Institutes of Health (NIH) campus in Bethesda, Maryland, studying pre- and post-mortem changes in the neurochemistry of patients with Alzheimer's disease and Down syndrome.
During my time at the NIH, I started a project looking at developing inhibitors of acetylcholinesterase for the treatment of Alzheimer's disease. From there, I joined the Merck Sharp and Dohme Neuroscience Research Centre in Harlow where I worked from 1989-2006 on a variety of in vitro and in vivo aspects of neuroscience drug discovery. When the site closed in as an indirect consequence of the Merck blockbuster drug Vioxx being taken off the market, I joined Janssen Pharmaceuticals, the pharmaceutical arm of Johnson & Johnson, where I worked from 2006 to 2012 (initially in La Jolla and then, attracted by the beer, chips and chocolate, in Beerse, Belgium).
I left the pharmaceutical industry to join the University of Sussex to help establish, with Prof. Simon Ward, the Sussex Drug Discovery Centre which, along with the addition of Prof. Martin Gosling gained a reputation for neuroscience drug discovery and ion channel pharmacology in particular.
In summer 2017, Simon and myself chose to move to Cardiff, attracted by the excellence of the disease mechanism and clinical science and the quality and collaborative spirit of the investigators with whom we will be interacting. However, we maintain our contacts with Martin who remains a key collaborator and allows us to expand our interest in ion channel pharmacology.
Ward, S.et al. 2019. Pharmacological characterisation of MDI-222, a novel AMPA receptor positive allosteric modulator with an improved safety profile. Journal of Psychopharmacology (10.1177/0269881119872198)
Maramai, S.et al. 2019. Subtype selective y-Aminobutyric acid type A receptor (GABAAR) modulators acting at the benzodiazepine binding site: An update. Journal of Medicinal Chemistry (10.1021/acs.jmedchem.9b01312)
Raulin, A.et al. 2019. The molecular basis for apolipoprotein E4 as the major risk factor for late-onset Alzheimer's disease. Journal of Molecular Biology 431(12), pp. 2248-2265. (10.1016/j.jmb.2019.04.019)
Kraft, L., Serpell, L. C. and Atack, J. R. 2019. A biophysical approach to the identification of novel ApoE chemical probes. Biomolecules 9(2), article number: 48. (10.3390/biom9020048)
Noble, J. W.et al. 2018. The X-ray structure of human calbindin-D28K: an improved model. Acta Crystallographica. Section D: Structural Biology 74(10), pp. 1008-1014. (10.1107/S2059798318011610)
Duke, A. N.et al. 2018. Evidence that sedative effects of benzodiazepines involve unexpected GABAA receptor subtypes: Quantitative observation studies in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics 366(1), pp. 145-157. (10.1124/jpet.118.249250)
Kraft, L.et al. 2018. Co-crystallization of human inositol monophosphatase with the lithium mimetic L-690,330. Acta Crystallographica. Section D: Structural Biology 74(10), pp. 973. (10.1107/S2059798318010380)
West, R. A.et al. 2017. African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase. European Journal of Medicinal Chemistry 141, pp. 676-689. (10.1016/j.ejmech.2017.09.067)
Khan, R.et al. 2017. Combining Sanford Arylations on Benzodiazepines with the nuisance effect. Advanced Synthesis & Catalysis 359(18), pp. 3261-3269. (10.1002/adsc.201700626)
Hornyak, P.et al. 2016. Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2. Biochemical Journal 473(13), pp. 1869-1879. (10.1042/BCJ20160180)
Gaekens, T.et al. 2016. Lipophilic nalmefene prodrugs to achieve a one-month sustained release. Journal of Controlled Release 232, pp. 196. (10.1016/j.jconrel.2016.04.029)
Spurny, R.et al. 2015. Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America 112(19), article number: E2543. (10.1073/pnas.1418289112)
Atack, J. R.et al. 2014. JNJ-40255293, a novel adenosine A2A/A1 antagonist with efficacy in preclinical models of Parkinson's Disease. ACS Chemical Neuroscience 5(10), pp. 1005-1019. (10.1021/cn5001606)
Walker, S.et al. 2014. Development of an oligonucleotide-based fluorescence assay for the identification of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors. Analytical Biochemistry 454, pp. 17-22. (10.1016/j.ab.2014.03.004)
Lavreysen, H. and Atack, J. 2014. Receptors: Functional assays. In: Stolerman, I. P. and Price, L. H. eds. Encyclopedia of Psychopharmacology. Berlin and Heidelberg: Springer, (10.1007/978-3-642-27772-6_208-2)
Lavreysen, H.et al. 2013. Pharmacological characterization of JNJ-40068782, a new potent, selective, and systemically active positive allosteric modulator of the mGlu2 receptor and its radioligand [3H]JNJ-40068782. Journal of Pharmacology and Experimental Therapeutics 346(3), pp. 514-527. (10.1124/jpet.113.204990)
Shinday, N. M.et al. 2013. Reinforcing effects Of compounds lacking intrinsic efficacy at α1 subunit-containing GABAA receptor subtypes in midazolam- but not cocaine-experienced Rhesus Monkeys. Neuropsychopharmacology 38(6), pp. 1006-1014. (10.1038/npp.2012.265)
Langlois, X.et al. 2012. Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia. Journal of Pharmacology and Experimental Therapeutics 342(1), pp. 91-105. (10.1124/jpet.111.190702)
Mirza, N. R., Atack, J. and Wafford, K. 2012. Receptor subtypes: novel targets for novel medicines. Advances in Pharmacological Sciences 2012, article number: 529861. (10.1155/2012/529861)
Swanson, D. M.et al. 2011. The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y2 receptor. Bioorganic and Medicinal Chemistry Letters 21(18), pp. 5552-5556. (10.1016/j.bmcl.2011.06.136)
Fischer, B. D.et al. 2011. Contribution of GABAA receptors containing α3 subunits to the therapeutic-related and side effects of benzodiazepine-type drugs in monkeys. Psychopharmacology 215(2), pp. 311-319. (10.1007/s00213-010-2142-y)
Atack, J.et al. 2011. MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans. Journal of Psychopharmacology 25(3), pp. 314-328. (10.1177/0269881109354927)
Atack, J.et al. 2011. Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist. Journal of Psychopharmacology 25(3), pp. 329-344. (10.1177/0269881109354928)
Atack, J. 2011. GABAA receptor subtype-selective modulators. I. α2/α3-selective agonists as non-sedating anxiolytics. Current Topics in Medicinal Chemistry 11(9), pp. 1176-1202. (10.2174/156802611795371350)
Atack, J. 2011. GABAA receptor subtype-selective modulators. II. α5-selective inverse agonists for cognition enhancement. Current Topics in Medicinal Chemistry 11(9), pp. 1203-1214. (10.2174/156802611795371314)
Eng, W.et al. 2010. Occupancy of human brain GABAA receptors by the novel α5 subtype-selective benzodiazepine site inverse agonist α5IA as measured using [11C]flumazenil PET imaging. Neuropharmacology 59(7-8), pp. 635-639. (10.1016/j.neuropharm.2010.07.024)
Atack, J. R. 2010. Development of subtype-selective GABAA receptor compounds for the treatment of anxiety, sleep disorders and epilepsy. In: Monti, J. M., Pandi-Perumal, S. R. and Mohler, H. eds. GABA and Sleep. Basel: Springer, pp. 25-72., (10.1007/978-3-0346-0226-6_2)
Letavic, M. A.et al. 2010. Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: Identification of candidates for clinical development. Bioorganic and Medicinal Chemistry Letters 20(14), pp. 4210-4214. (10.1016/j.bmcl.2010.05.041)
Stocking, E. M.et al. 2010. Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists. Bioorganic and Medicinal Chemistry Letters 20(9), pp. 2755-2760. (10.1016/j.bmcl.2010.03.071)
Dixon, C. I.et al. 2010. Cocaine effects on mouse incentive-learning and human addiction are linked to α2 subunit-containing GABAA receptors. Proceedings of the National Academy of Sciences 107(5), pp. 2289-2294. (10.1073/pnas.0910117107)
Licata, S. C.et al. 2010. Discriminative stimulus effects of L-838,417 (7-tert-butyl-3-(2,5-difluoro-phenyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-[1,2,4]triazolo[4,3-b]pyridazine): Role of GABAA receptor subtypes. Neuropharmacology 58(2), pp. 357-364. (10.1016/j.neuropharm.2009.10.004)
Shoblock, J. R.et al. 2010. In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y2 receptor. Psychopharmacology 208(2), pp. 265-277. (10.1007/s00213-009-1726-x)
Atack, J. R. 2010. Preclinical and clinical pharmacology of the GABAA receptor α5 subtype-selective inverse agonist α5IA. Pharmacology and Therapeutics 125(1), pp. 11-26. (10.1016/j.pharmthera.2009.09.001)
Atack, J. R.et al. 2010. Benzodiazepine binding site occupancy by the Novel GABAA receptor subtype-selective drug 7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in rats, primates, and humans. Journal of Pharmacology and Experimental Therapeutics 332(1), pp. 17-25. (10.1124/jpet.109.157909)
Ator, N. A.et al. 2010. Reducing abuse liability of GABAA/Benzodiazepine ligands via selective partial agonist efficacy at α1 and α2/3 subtypes. Journal of Pharmacology and Experimental Therapeutics 332(1), pp. 4-16. (10.1124/jpet.109.158303)
Atack, J. R. 2009. GABAA receptor α2/α3 subtype-selective modulators as potential nonsedating anxiolytics. Current Topics in Behavioral Neuroscience 2, pp. 331-360. (10.1007/7854_2009_30)
I am currently engaged in projects identifying molecules that interact with specific subtypes of the GABAA receptor or the AMPA subtype of glutamate receptor. These projects involve multidisciplinary teams of scientists using innovative medicinal chemistry (led by Prof. Simon Ward) and electrophysiology (Profs. Martin Gosling and Jerry Lambert and the University of Sussex and Dundee University, respectively) as well as a number of industrial collaborators (e.g., GSK and AstraZeneca).
I am also involved in a number of additional early-stage projects studying the mechanism of action of lithium and the role of ApoE4 in Alzheimer's disease as well as novel approaches to modulating NMDA and kainate glutamate ion channel function.
I am driven by the desire to develop new treatments for the neurodegenerative and psychiatric disorders that have a profound impact on so many of our families and for which there remains a significant unmet medical need.
Bringing a new generation of drugs to patients
Turning leading research into novel medicines
External profiles


With a light output of 658 lumens, equivalent to 9.64-watts and an average rated lamp life of 36,000 hours, about 16 years of normal use, this is a job you will probably only have to do once. The kit includes three LED linkable pucks, three mounting caps, one dimmer control unit with a five-foot plug in cord, screws and mounting clips. The kit is expandable to six lights with LED add-on pucks.


text:
Mackinac Gazette
Meet the Outstanding (and Responsible) Senior Geoff Patterson
For every graduating class, each academic department at GVSU chooses a single "outstanding graduate" to recognize. For the mathematics department in 2009, the recipient of this distinguished honor is Geoff Patterson of Haslett, Michigan. While we often hear of students changing majors during college, typically we think of transitions from, say, engineering to mathematics: but Geoff started out as a film major, and in fact he chose GVSU for college because of the quality of the film and video program. We are delighted that he changed his mind and pursued a degree in mathematics.
Geoff shares that he has fallen in love with Grand Valley during his time here. "Most aspects of the university fit me perfectly," he says, "and those which did not originally fit have shaped me for the better." He has especially appreciated the teachers and smaller class sizes, granting him a very personalized college education. When asked about his favorite courses, Geoff named a few. Euclidean Geometry helped him begin to see some of the beautiful results that occur in mathematics, and The Mathematics of Voting and Elections enabled him to appreciate a very applied aspect of mathematics. Moreover, his Modern Algebra II course was also very enjoyable as it opened a door to the world of much more theoretical mathematics. Geoff was also a participant in the GVSU mathematics REU, a summer research experience that has had a major impact on his future plans while simultaneously giving him an even greater appreciation for math in general.
Following graduation, Geoff plans to continue his education by pursuing a PhD in mathematics. At the time of this writing, he has been accepted to University of Hawaii and Clemson University and is awaiting replies from several other schools. Ten years from now he hopes to be engaged in mathematics research, perhaps by working at an organization like the National Security Agency. Regardless, he says "I hope to never stop learning math."
Current and former students know how much work the mathematics major is. So they might be surprised to learn how many different things Geoff finds to do in his spare time. For example, this man of many hobbies spends some of his spare time surfing on Lake Michigan, playing drums and guitar, running, playing beach volleyball, playing softball, and programming computers. He is also the owner of Responsible Boy Taxi, a safe-ride service for GVSU students on weekend nights, at which he employs more than 10 other students and owns several vehicles. In Geoff's words, "I am rarely unoccupied."
As he departs GVSU this spring, Geoff has some words of wisdom for students with time left at Grand Valley: "talk to your advisor at least a few times a year, partly to ensure you are taking the right courses, but also to look for summer internships or research opportunities so that when you are not taking classes you can be gaining experience in other ways."
Page last modified June 9, 2017


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Newspaper Clippings – Mercer County, Kentucky
By Kentucky Kindred Genealogical Research on March 18, 2013 • ( Leave a comment )
From Mercer County, Kentucky
Miscellaneous information from newspaper clippings in scrapbooks
Henry C. Bohon of Harrodsburg and Miss Sallie Knight of Nicholasville were married September 1869.
James R. Elgin and Miss N. Bishop, both of Mercer County, were married October 1, 1869.
W. L. Linley of Springfield, Missouri, and Miss Fanny May, daughter of Captain Charles May of Boyle County, were married October 5, 1869.
Colonel Richard Huff, age 88, died at his residence in Mercer County, September 6, 1869. He was a native of Virginia and came to Mercer County in 1786. His father fought for Independence in 1776 and Richard fought in the War of 1812.
The Golden Wedding Anniversary of William Hutchison and Margaret Bland was celebrated at their residence in Mercer County on October 24, 1869. Those present included his brothers Elijah and Thomas, and the couple's children: John, Thomas and Joseph Hutchison and Mrs. Harvey, Mrs. Kirkland and Mrs. Huff.
E. K. Shewmaker and Mattie P. Terhune of Mercer County were married October 21, 1869.
Eugene A. Terhune and Anna S. Vanarsdall were married October 21, 1869.
William Richards and Mary Norvell of Mercer County were married October 26, 1869.
Richard M. Cox and Martha Cox were married at the residence of Henry Nield October 27, 1869.
James H. Lowery, of Missouri, married Lizzie Matheny, of Harrodsburg, October 27, 1869.
Squire Bunton is nearly 75 years old. (The Kentucky People, Harrodsburg, Kentucky, October 29, 1869).
Harrison Dunn, an old citizen of Mercer County, moved with his family to Franklin, Indiana, last week. (October 17, 1873)
Marriage licenses granted to Jerome B. Griffin, July 11, 1877, and on July 26, 1877, to Henry H. Shearin, Georgie A. Gibson and Theodore D. Lont to Isabella Rice.
Mr. Pius Sea died in Washington County, age 23, July 13, 1877.
Marriage license issued to E. Lambert and Mary Brown August 9, 1877.
Mrs. Mary E. Handy died August 6, 1877, interred in family burial ground.
Dr. Beriah Magoffin was born 24th of July 1800 in city of Newry, Ireland. He died August 5, 1877, Mercer County, Kentucky.
John Smock and Sallie Coghill married at residence of David Walters June 18, 1879.
John C. Burrus and Susie F. Munday were married June 14, 1879.
S. R. Hampton of Jessamine County and Lillie Terhune of Mercer County were married June 17, 1879.
William Douglas and Alice Johnson were married January 26, 1881.
Dr. Marcus Sutherland and Miss Jimmie Terhune were married January 27, 1881.
Mr. Solon P. Eastland and Miss Lou Clelland, daughter of W. E. Clelland, were married January 26, 1881.
John W. Powell of McAfee and Mrs. Maggie McGrorty of Harrodsburg were married January 25, 1881.
John Van Anglin, an old citizen of Harrodsburg, died March 31, 1881.
Dr. Joseph Addison Thompson, born Harrodsburg July 4, 1805, married Miss Amanda Singleton of Mississippi, died Harrodsburg, April 2, 1881. She died about 3 years previous, leaving him a childless widower.
Mrs. Barthena Rose, wife of Charles Rose, died in Danville, Indiana, April 19th 1881, in her 76th year. She was born and married in Mercer County, Kentucky, and lived here for several years. She leaves a husband of more than 50 years, also four children.
Mrs. Pollie K. Morgan, age 72, of Covington, Kentucky, died May 7th, 1881. Her sons have been residents of Mercer County, Kentucky, for the past four years.
William Green and Emma McAndrews of Burgin married May 18, 1881.
Dr. J. J. Polk of Perryville, age 79, died May 1881.
J. M. Starks, of Mercer County, died May 25th 1881. His remains will be taken to Lexington for burial.
Major William Daviess, born June 17th 1811, died at his home, Hayfields, in Mercer County, July 29, 1881. He married Mariah Thompson, second daughter of John B. Thompson, and she survives him.
Miss Anna E. Rupley died at Perryville, Kentucky, July 26, 1881. Interred at Spring Hill Cemetery, Harrodsburg.
Mrs. Lucy Bronaugh, age 43, died July 18, 1881.
Charles Edwin Williams, physician and surgeon, was born July 1st 1800, in Montgomery County, Kentucky, son of Raleigh Williams, early pioneer of Kentucky, and of the stock of Roger Williams, according to family tradition. His mother was a Lutrelle, of a French Huguenot family. He married Arabella Dodge of Winchester, who died January 1832, leaving three children: John Augustus of Daughters College, Mary Dorcas, wife of Regent Bowman, and Arabella, the wife of Robert Hawes Buckner of Missouri. In 1834, he married Louan Bush Morrow, daughter of Colonel Robert Morrow, of Bath County. One child of this marriage, Charles E. Williams, Jr., is living. Dr. Charles E. Williams, Sr., died at Harrodsburg, Kentucky, August 9, 1881.
Lula West, age one month, daughter of Millie and George R. West, died August 13, 1881.
Miss Bettie Lowe, age 21, died August 18th 1881. Funeral and interment at her grandfather's, Mr. W. B. Vivion.
Mrs. Judith Smith, age 82, died at Dr. Stevenson's August 13, 1881. Interment at Danville, Kentucky.
Mrs. Joe Anna Head, wife of R. f. Head, died August 17, 1881.
T. Rowan Bridges, age 58, a native of Harrodsburg and son of the late Honorable John L. Bridges, died in Bolivar County, Mississippi, at the home of his sister, Mrs. E. A. Peake.
William A. Shy of Mercer County, and Mary M. Gentry of Lincoln County, were married September 7th 1881.
Mrs. Sarah A. Daniel, wife of W. H. Daniel, and eldest daughter of the late Abram Smith of Mercer County, died at her home in Columbia, Missouri, on September 2nd 1881.
Mrs. Evaline Davis Lung died in Mercer County, September 5th 1881.
Mrs. Benjamin Smith, born in Madison County, Virginia, October 22, 1799, died August 14, 1881, at the home of Dr. A. T. Stephenson. At age 15 she was married to Mr. Page of Virginia, by whom she has one son, Dr. J. C. Page of St. Louis. She was left a young widow and then married Benjamin Smith, of Shenandoah County, Virginia, who is now 90 years old, and to whom she was married 56 years. The Smith's children: Mrs. P. T. Gentry, dec'd, F. M. Smith of Lexington, and Dr. Stephenson.
Categories: Family Stories, Genealogy Ramblings, Newspaper Articles
Tagged as: Benjamin Smith, Captain Charles May, Charles Edwin Williams, Charles Rose, Colonel Richard Huff, deaths, Dr. Joseph Addison Thompson, Dr. Marcus Sutherland, Evaline Davis, family, genealogy research, Harrison Dunn, Henry C. Bohon, James R. Elgin, Jerome B. Griffin, John Van Anglin, Kentucky Kindred Genealogy, Lizzie Matheny, Margaret Bland, Marriage records, Mattie P. Terhune, Mercer County Kentucky, newspaper articles, Sallie Coghill, Sallie Knight, Solon P. Eastland, William Hutchison
Today In Genealogy History – March 18


text:
GIUK gap (fra engelsk: Greenland, Iceland, UK gap) er havområderne mellem Grønland, Island og nordlige deler af Storbritannien.  Udtrykket bruges i militær sammenhæng, og stammer fra tiden under anden verdenskrig.

Resume
GIUK gap er en forkortelse af det engelske udtryk Greenland-Iceland-United-Kingdom-gap.Udtrykket benyttes ofte i militærstrategisk sammenhæng, og det dækker over det geografiske område mellem Grønland, Island og Storbritannien, der historisk har været en strategisk flaskehals for militære magter. Nutidigt bliver områdets strategiske betydning stadigt mere udtrykt af de dominerende politiske og militære aktører i området.

Definition og geografi
Greenland-Iceland-United-Kingdom-gap (GIUK gap)[1] også kaldet GIUK-gapet på dansk er et geografisk område afgrænset af Grønland mod vest, Storbritannien Storbritanien](UK) mod øst og med Island i midten. Betegnelsen dækker normalvis over havområderne og/eller luftrummet i Nordatlanten, der netop er afgrænset af Grønland, Island og UK.

Strategisk betydning
Betegnelsen anvendes i militære og politiske sammenhænge i relation til sømilitære eller luftmilitære operationer, strategierog doktriner.[2]

GIUK gap har, og forventes at få, stadig større strategisk betydning for de politiske aktører i området.[3] Dette skyldes grundlæggende, at GIUK gap er "en strategisk flaskehals (red. på engelsk chokepoint) for russiske ubådes evne til at operere i Nordatlanten"[4]og dermed har området essentiel strategisk betydning for USA og NATO-alliancen i tilfælde af en krise - ligesom det havde det under den Kolde Krig.[5]

Nuklear afskrækkelse
Russiske ubådes evne til at operere i Nordatlanten skal ses i kontekst af en mangeårig nuklear afskrækkelsesstrategi imellem USA og Rusland, der oprustningsmæssigt toppede under den Kolde Krig. De to landes fortsatte kapaciteter til nuklear afskrækkelse findes blandt andet i strategiske missilubåde, der er afhængige af at kunne operere i GIUK gap, for at have maksimalt militært råderum.[6]

Øget militær aktivitet
Som følge af det øgede politiske og strategiske fokus på GIUK gap og Arktis generelt ses en øget militær øvelsesvirksomhed i området.[7] Disse øvelser spændender bredt i formål, fra træning af opgaver af mere civil karakter og støtte til lokalsamfund (f.eks. Search and RescueExercise (SAREX)) over militære sikkerhedsoperationer til træning af mere konventionel krigsførelse og beredskabsøvelser med henblik på at imødegå invasioner. De strategiske budskaber, som øvelsesaktiviteterne udsender spænder derfor også vidt fra at signalere øget samarbejde i mellem de Arktiske lande til at signalere evnen til at holde et højt militært beredskab på kort varsel.[8]

Kongeriget Danmarks Interesse i GIUK gap
I kraft af Kongeriget Danmarksgeografisk placering med Grønland som ydergrænse i GIUK gap og Danmark umiddelbart øst for området, så besidder Kongeriget Danmark et stort geografiske territorium med vigtig strategisk og geopolitisk betydning for dets nærmeste samarbejdspartnere i form af USA og mere generelt i NATO-alliancen. Dermed har Kongeriget Danmark et stort geopolitisk aktiv i form af Grønland, som der kan drages nytte af det transatlantiske samarbejde.[9]

Videre læsning
Kongeriget Danmarks interesser i Arktis (ikke kun GIUK gap) er beskrevet dybdegående i Forsvarsministeriets Arktis Analyse[10] "Forsvarsministeriets Fremtidige Opgave Løsning i Arktis" fra juni 2016.

I Bilag 2 til samme analyse ("Sikkerhedspolitisk Redegørelse om Udviklingen i Arktis – AGFOA Strategi") redegøres der for den geopolitiske og sikkerhedspolitiske situation i Arktis.

Antiubådskrigsførsel(Anti Submarine Warfare) i GIUK gap er yderligere beskrevet på Wikipedia-siden med samme overskrift.

Referencer

 Henriksen, Anders, og Jon Rahbek-Clemmensen. 2017. "Grønlandskortet - Arktis' betydning for Danmarks indflydelse i USA". Center for Militærestudier, Københavns Universitet.
 "Sikkerhedspolitisk redegoerelse om udviklingen i arktis.pdf". u.å. Set 2. oktober 2019.https://fmn.dk/nyheder/Documents/arktis-analyse/bilag2-Sikkerhedspolitisk-redegoerelse-om-udviklingen-i-arktis.pdf.
 [1](Henriksen og Rahbek-Clemmensen 2017 , 10)

 [2](Henriksen og Rahbek-Clemmensen 2017, 10).

 [3](Henriksen og Rahbek-Clemmensen 2017, 10).

 [4](Henriksen og Rahbek-Clemmensen 2017, 10).

 [5](Henriksen og Rahbek-Clemmensen 2017, 10).

 [6]("Sikkerhedspolitisk redegoerelse om udviklingen i arktis.pdf" u.å., 14)

 [7]("Sikkerhedspolitisk redegoerelse om udviklingen i arktis.pdf" u.å., 16)

 [8]("Sikkerhedspolitisk redegoerelse om udviklingen i arktis.pdf" u.å., 17)

 [9](Henriksen og Rahbek-Clemmensen 2017, IV)

 [10]("Forsvarsministeriets fremtidige opgaveløsning i Arktis" 2016)
Flåder
Atlanterhavet
Den kolde krig


text:
Lorenzo Daniel (né le ) est un athlète américain spécialiste du 200 mètres.

Le , Lorenzo Daniel établit la meilleure performance de l'année sur 200 mètres en signant le temps de 20 s 07 lors de la réunion de Starkville. Âgé de dix-neuf ans, il améliore de six centièmes de secondes le record du monde junior de la discipline détenu par son compatriote Roy Martin. Cette meilleure performance mondiale junior ne sera améliorée que dix-neuf ans plus tard par le Jamaïcain Usain Bolt, auteur de 19 s 93 le  lors des Jeux de la CARIFTA à Hamilton.

Son record personnel sur 200 m est de 19 s 87, établi le  à Eugene en finale des Championnats NCAA.

Liens externes

Notes et références

Sprinteur américain
Coureur de 200 mètres
Naissance en mars 1966


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This dog has been reserved, which means that they will be meeting people so that a trial can take place. You can still apply for adoption, however please note that if the trial period is successful then Zulu will no longer be available to be rehomed.