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Anatomy 20
Bone Marrow Cells
Granulocytes
Antilymphocyte Serum
Thymus Gland
Blood Cells
Stromal Cells
Megakaryocytes
Clone Cells
Organisms 11
Transplantation Chimera
Radiation Chimera
Mice, Inbred BALB C
Mice, Inbred C3H
Mice, Inbred Strains
Mice, Inbred AKR
Diseases 52
Graft vs Host Disease
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia, Myeloid, Acute
Hematologic Neoplasms
Hepatic Veno-Occlusive Disease
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Bone Marrow Neoplasms
Leukemia, Myeloid
Lymphoma, Non-Hodgkin
Severe Combined Immunodeficiency
Hematologic Diseases
Pancytopenia
Cytomegalovirus Infections
Bone Resorption
Hodgkin Disease
Bone Neoplasms
Immunologic Deficiency Syndromes
Opportunistic Infections
Postoperative Complications
Blood Group Incompatibility
Neoplasm, Residual
Bone Diseases
beta-Thalassemia
Lymphoproliferative Disorders
Leukemia, Lymphoid
Leukemia, Myelomonocytic, Acute
Anemia, Refractory, with Excess of Blasts
Fanconi Anemia
Histiocytosis, Non-Langerhans-Cell
Primary Myelofibrosis
Pneumonia, Viral
Gonadal Disorders
Bronchiolitis Obliterans
Mucopolysaccharidosis I
Thrombocytopenia
Chemicals and Drugs 28
Busulfan
Cyclophosphamide
HLA Antigens
Carmustine
Cytarabine
Granulocyte Colony-Stimulating Factor
Melphalan
Etoposide
Cyclosporins
Antigens, CD
Vincristine
Podophyllotoxin
ABO Blood-Group System
Isoantigens
Analytical, Diagnostic and Therapeutic Techniques and Equipment 66
Transplantation, Homologous
Transplantation, Autologous
Whole-Body Irradiation
Transplantation Conditioning
Hematopoietic Stem Cell Transplantation
Bone Marrow Purging
Histocompatibility Testing
Transplantation, Isogeneic
Combined Modality Therapy
Remission Induction
Lymphocyte Depletion
Leukocyte Transfusion
Colony-Forming Units Assay
Survival Analysis
Actuarial Analysis
Lymphocyte Transfusion
Antineoplastic Combined Chemotherapy Protocols
Disease-Free Survival
Fatal Outcome
Cord Blood Stem Cell Transplantation
Immunophenotyping
Pancreas Transplantation
Islets of Langerhans Transplantation
Peripheral Blood Stem Cell Transplantation
Skin Transplantation
Hematopoietic Stem Cell Mobilization
Blood Cell Count
Salvage Therapy
Life Tables
Cell Count
Hemibody Irradiation
Mesenchymal Stem Cell Transplantation
Graft Enhancement, Immunologic
Transplantation, Heterologous
Platelet Transfusion
Transplantation, Heterotopic
Bone Transplantation
Drug Evaluation
Lymphocyte Count
Heart-Lung Transplantation
Psychiatry and Psychology 1
Phenomena and Processes 32
Graft Survival
Histocompatibility
Hematopoiesis
Bone Remodeling
Transplantation Immunology
Graft vs Host Reaction
Graft vs Tumor Effect
Graft vs Leukemia Effect
Chimerism
Transplantation Tolerance
Bone Development
Immunocompromised Host
Cell Lineage
Bone Regeneration
Host vs Graft Reaction
Anthropology, Education, Sociology and Social Phenomena 1
Information Science 3
Named Groups 2
Living Donors
Health Care 12
Tissue and Organ Procurement
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesNamed Groups
Bone Marrow TransplantationBone MarrowTransplantation, HomologousBone Marrow CellsGraft vs Host DiseaseTransplantation, AutologousWhole-Body IrradiationBone and BonesAnemia, AplasticTransplantation ConditioningHematopoietic Stem Cell TransplantationLeukemiaLiver TransplantationTransplantation ChimeraTissue DonorsGraft SurvivalBusulfanBone Marrow PurgingHistocompatibility TestingHematopoietic Stem CellsHistocompatibilityCyclophosphamideTransplantation, IsogeneicBone Marrow DiseasesKidney Transplantation
platelet
Both groups of patients (i.e. nonresponders to immunosuppressive therapy and responders with persistent thrombocytopenia) require regular platelet transfusions, which are expensive and inconvenient, and are a risk for further serious bleeding complications. (clinicaltrials.gov)
Because a paucity of megakaryocytes and decreased platelet production is responsible for thrombocytopenia in aplastic anemia patients, we now propose this Phase 2, non-randomized pilot study of eltrombopag in aplastic anemia patients with immunosuppressive therapy refractory thrombocytopenia. (clinicaltrials.gov)
Severe plastic anemia can lead to problems with bone marrow platelet production and result in low blood platelet counts, which require frequent platelet transfusions to improve blood clotting. (clinicaltrials.gov)
Severe aplastic anemia (SAA) is a life-threatening blood disease which can be effectively treated with immunosuppressive drug regimens or allogeneic stem cell transplantation. (clinicaltrials.gov)
However, 20-40% of patients without transplant options do not respond to immunosuppressive therapies, and have persistent severe thrombocytopenia. (clinicaltrials.gov)
Evaluations will include blood samples and periodic bone marrow biopsies. (clinicaltrials.gov)
Potential cures include bone marrow transplantation and gene therapy. (wikipedia.org)
The Bone Marrow Transplantation and Gene Therapy Working Party works to "improve the outcome of transplant and gene therapy for severe congenital immunodeficiencies. (wikipedia.org)
The experimental technique of gene therapy may offer cures in the future. (wikipedia.org)
Genetic medicine is a newer term for medical genetics and incorporates areas such as gene therapy, personalized medicine, and the rapidly emerging new medical specialty, predictive medicine. (wikipedia.org)
Due to its similarity to X-SCID in humans, breeding colonies of affected dogs have been created in order to study the disease and test treatments, particularly bone marrow transplantation and gene therapy. (wikipedia.org)
For example, the defining test for bone marrow or hematopoietic stem cells (HSCs) is the ability to transplant the cells and save an individual without HSCs. (wikipedia.org)
As Head of Hematology at the British Columbia Cancer Agency and the University of British Columbia for 18 years (1985-2003) he engineered the building of one of the first and largest bone marrow transplant programs in Canada. (wikipedia.org)
The US FDA has also cleared Pluristem to commence patient enrollment in a Phase I trial of its PLX-R18 cells to treat insufficient hematopoietic recovery following bone marrow transplant. (wikipedia.org)
1990 Joanne Kurtzberg establishes the Duke Pediatric Blood and Marrow Transplant Program. (wikipedia.org)
1994 Dr. Louise Markert demonstrates that babies born with no immune system, a fatal condition known as complete DiGeorge syndrome, can be cured with thymus transplantation. (wikipedia.org)
There are three known accessible sources of autologous adult stem cells in humans: Bone marrow, which requires extraction by harvesting, that is, drilling into bone (typically the femur or iliac crest). (wikipedia.org)
Embryonic cell lines and autologous embryonic stem cells generated through somatic cell nuclear transfer or dedifferentiation have also been proposed as promising candidates for future therapies. (wikipedia.org)
Eaves' personal research has focused on leukemia where he pioneered "culture purging" as a novel approach to doing autologous bone marrow transplantation for chronic myelogenous leukemia. (wikipedia.org)
hematopoietic
Results from the study suggest that PLX-R18 is safe and may significantly improve outcomes after bone marrow failure or hematopoietic cell transplantation. (wikipedia.org)
Congenital dyserythropoietic anemia type III (CDA III) is a rare autosomal dominant disorder characterized by macrocytic anemia, bone marrow erythroid hyperplasia and giant multinucleate erythroblasts. (wikipedia.org)
Roquinimex has been investigated as a treatment for some cancers (including as adjuvant therapy after bone marrow transplantation in acute leukemia) and autoimmune diseases, such as multiple sclerosis and recent-onset type I diabetes. (wikipedia.org)
PLX-R18 were initially developed with Prof Raphael Gorodetsky at Hadassah Hospital for the treatment of acute radiation syndrome and enhancement of bone marrow regeneration. (wikipedia.org)
erythroblasts
Circulating erythroblasts and erythroblasts in the bone marrow show various morphologic abnormalities. (wikipedia.org)
resulting in anemia
In some individuals, the disease comes to light only after the cancerous cells overwhelm the bone marrow resulting in anemia producing tiredness or weakness. (wikipedia.org)
No cures for lysosomal storage diseases are known, and treatment is mostly symptomatic, although bone marrow transplantation and enzyme replacement therapy (ERT) have been tried with some success. (wikipedia.org)
He was also among the first scientists to identify X-inactivation as the genetic basis of tissue mosaicism in female mammals, and pioneered a number of medical treatments, including bone marrow transplantation techniques. (wikipedia.org)
Adult stem cells are frequently used in various medical therapies (e.g., bone marrow transplantation). (wikipedia.org)
A California life science commercial entity that is not actively engaged in researching or developing therapies with pluripotent or progenitor stem cells. (wikipedia.org)
SCID mice are routinely used as model organisms for research into the basic biology of the immune system, cell transplantation strategies, and the effects of disease on mammalian systems. (wikipedia.org)
1982 Pediatric immunologist Rebecca Buckley uses bone marrow transplantation to restore the immune systems of children born with severe combined immunodeficiency, also known as bubble boy disease. (wikipedia.org)
Duke University School of Medicine also includes PhD programs in the basic sciences and education and training programs in other health professions, including the top-ranked Physician Assistant and Doctor of Physical Therapy programs, a Primary Care Leadership Track, Master of Biomedical Sciences, MS and PhD in Biostatistics, and Master of Management in Clinical Informatics. (wikipedia.org)
rapidly
Two months thereafter, with the patient's condition deteriorating rapidly, the Director of Bone Marrow Transplantation, Cell Therapy and Transplantation Research Center at Hadassah felt that all available options had been exhausted and turned to Pluristem's PLX cells. (wikipedia.org)
Working under the supervision of Bruce (AACR Award), and in association with Till and McCulloch and a vibrant group of graduate students and post-doctoral fellows, Eaves completed his PhD in Medical Biophysics at the University of Toronto with a thesis entitled Studies on the Control of Murine Bone Marrow Function (1974). (wikipedia.org)
In May 2012, Pluristem reported that its experimental PLacental eXpanded cells were injected into the muscles of a 7-year-old Romanian girl undergoing treatment for bone marrow aplasia disease at the Hadassah Medical Center in Jerusalem. (wikipedia.org)
In September 2012 Pluristem reported saving the life of a third bone marrow disease patient using its PLacental eXpanded cell treatment, again at Jerusalem's Hadassah Medical Center and again under the terms of compassionate use. (wikipedia.org)
hematopoietic stem
Optimization of blood transfusion service, harvesting, storage and transplantation of hematopoietic stem cells. (fnkc.ru)
We developed and validated a fluorescent marking methodology for clonal tracking of hematopoietic stem and progenitor cells (HSPCs) with high spatial and temporal resolution to study in vivo hematopoiesis using the murine bone marrow transplant experimental model. (jove.com)
Bone marrow transplant is the only known cure for sickle cell disease, which can cause excruciating pain, strokes, damage to organs, and a shortened life expectancy. (wolfsonchildrens.com)
Our sickle cell team provides comprehensive care, specialized treatment and evaluation for possible bone marrow transplant. (wolfsonchildrens.com)
The day a child receives a bone marrow transplant can be a day of hope and new beginnings for the family. (wolfsonchildrens.com)
Voriconazole is used to treat invasive aspergillosis and candidiasis and fungal infections caused by Scedosporium and Fusarium species, which may occur in immunocompromised patients, including people undergoing allogeneic bone marrow transplant (BMT), who have hematologic cancers or who undergo organ transplants. (wikipedia.org)
Aggressive treatment with antibiotics is required and bone marrow transplant is common. (wikipedia.org)
Patients undergoing bone marrow transplant, specifically from a matched sibling, have a higher 5 year survival rate than those receiving a transplant from other donors. (wikipedia.org)
Similarly, in bone transplant, stem cells are able to find their way back through tracking mechanisms. (wikipedia.org)
mononuclear cells
Bone marrow-derived mononuclear cells (MNCs) include a variety of stem and progenitor cells, such as endothelial progenitor cells (EPCs), and contribute to pathological neovascularization. (ahajournals.org)
However, counting CD34+ mononuclear cells may overestimate myeloid blasts in bone marrow smears due to hematogones (B lymphocyte precursors) and CD34+ megakaryocytes. (wikipedia.org)
umbilical cord
Transplantation of stem cells are taken from the bone marrow, peripheral blood or umbilical cord of healthy, matched donors. (wikipedia.org)
allogeneic
According to published evidence the only treatment with some potential to improve BPDCN outcome is intensive chemotherapy consolidated by allogeneic hematopoietic stem cell transplantation. (czytelniamedyczna.pl)
Typically, a diagnosis of DBA is made through a blood count and a bone marrow biopsy. (wikipedia.org)
BPDCN are characterized by co-expression of CD4 and CD56 antigens in the absence of any specific myeloid or lymphoid lineage or markers, primary skin infiltrations followed by bone marrow involvement, and aggressive clinical course. (czytelniamedyczna.pl)
Emory's ability to develop improved therapies through clinical research is a key component of our clinical mission and gives patients access to the most advanced treatments available," says Jeffrey Lennox, MD, associate dean for clinical research in Emory University School of Medicine. (advancingyourhealth.org)
The team will factor in the severity of the condition, your child's age and tolerance to different kinds of medications and therapies, and choose from the latest clinical trials and treatment protocols. (wolfsonchildrens.com)
Through our work with the Children's Oncology Group and other pediatric cancer research groups, we have access to the latest clinical protocols and experimental therapies to give children the best chance for a positive outcome. (wolfsonchildrens.com)
Antibodies are used to quantify and purify hematopoietic progenitor stem cells for research and for clinical bone marrow transplantation. (wikipedia.org)
It was withdrawn from market in June 2010 when a clinical trial showed the drug increased patient death and added no benefit over conventional cancer therapies. (wikipedia.org)
This therapy is currently undergoing clinical trial and has cured a small number of children suffering from X-linked SCID and recessive allele SCID. (wikipedia.org)
endothelial progenitor
Truly endothelial, BOEC are progeny of a transplantable cell that originates in bone marrow, a putative endothelial progenitor. (jci.org)
In a recent Blood article, Anja Möricke , from the Department of Pediatrics at the Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, in Germany, and colleagues reported results from the open-label AIEOP-BFM ALL 2000 trial, which compared induction therapy with dexamethasone versus prednisone in 3,720 pediatric ALL patients. (ashclinicalnews.org)
Patients who have had radiation therapy in more than 35% of the bone marrow. (careacross.com)
however, some patients fail to respond to this cell therapy. (ahajournals.org)
A new study using cryoablation to decrease pain for patients who have cancer metastases in the bone is now underway throughout Emory Healthcare . (advancingyourhealth.org)
Called the "Multicenter Study of Cryoablation for Palliation of Painful Bone Metastases", or MOTION, the study aims to assess the effectiveness and safety of cryoablation therapy to treat patients with painful bone metastases and document the effects the procedure has on their condition. (advancingyourhealth.org)
Cryoablation provides an alternative for patients who haven't experienced relief from current pain therapies. (advancingyourhealth.org)
Annually, over 2,000 new patients are admitted, and more than 200 hematopoietic stem cell transplantations and 2,000 surgeries are performed in our Center. (fnkc.ru)
Patients achieving complete remission or partial remission after 6 months may continue therapy at the discretion of the principal investigator. (clinicaltrials.gov)
however, there are some highly effective enzyme replacement therapies for people with type 1 Gaucher disease and some patients with type 3 Gaucher disease. (wikipedia.org)
Serious side effects included severe myelosuppression (suppressed activity of bone marrow, which is involved in formation of various blood cells [found in 98% of patients]), disorder of the respiratory system, tumor lysis syndrome, Type III hypersensitivity, venous occlusion, and death. (wikipedia.org)
Later the onset of VOD was shown to occur at increased frequency in Gemtuzumab patients even following bone marrow transplantation. (wikipedia.org)
Among the patients evaluated for early toxicity, fatal toxicity rate was significantly higher in the gemtuzumab combination therapy group vs the standard therapy group. (wikipedia.org)
If the results show patients with low levels of lymphocytes, absence of granulocytes or absence of thymus then the patient may be suspected to have RD. RD can only be treated temporarily through Hematopoietic stem cell transplantation (HSCT) and Cytokine Therapy. (wikipedia.org)
This cure is commonly used in patients who are awaiting bone marrow transplantation. (wikipedia.org)
In a large study of 225 patients, 82% initially responded to this therapy, although many side effects were noted. (wikipedia.org)
When these findings are taken together, combination therapy with MNC transplantation and AM infusion may have additional or synergetic effects on therapeutic angiogenesis for the treatment of severe peripheral vascular disease. (ahajournals.org)
Over time, this excessive storage of fats can cause permanent cellular and tissue damage, particularly in the brain, peripheral nervous system, liver, spleen and bone marrow. (wikipedia.org)
A diagnosis of DBA is made on the basis of anemia, low reticulocyte (immature red blood cells) counts, and diminished erythroid precursors in bone marrow. (wikipedia.org)
hematological
Multimodality therapy of hematological malignancies, CNS and solid non-CNS tumours in children, adolescents and young adults. (fnkc.ru)
Bone marrow transplantation (BMT) can cure hematological aspects of DBA. (wikipedia.org)
Emory interventional radiologists freeze tumors in order to kill cancer cells in contact with the bone and reduce the size of the tumor. (advancingyourhealth.org)
Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). (wikipedia.org)
Our subsequent experimental work focused upon practical applications of BOEC: their use for gene therapy, tissue engineering, assessment of mutant gene effect, and discovery of heterogeneity in endothelial biology. (jci.org)
Hematopoietic stem cell transplantation for children with bone marrow failure syndromes, immune deficiencies, malignant and inherited disorders. (fnkc.ru)
Development of comprehensive approaches to the therapy of bleeding disorders. (fnkc.ru)
Furthermore, gene thereapies and bone marrow transplantation may prove to be effective for certain lipid storage disorders. (wikipedia.org)
It is associated with rheumatoid arthritis, Felty syndrome, myeloproliferative disorders, liver, kidney and bone marrow transplantation, cytotoxic drugs like azathioprine, mercaptopurine, thioguanine, antiretroviral drugs for HIV like didanosine and vitamin A. The disease is usually asymptomatic, slowly or non-progressive unless complications of portal hypertension develop. (wikipedia.org)
Finally, the diagnosis of HLH was confirmed by fulfilling diagnostic criteria for HLH and pathological analysis of bone marrow aspiration. (paperity.org)
Volumetric analyses over large areas reveal that spectrally coded HSPC-derived cells can be detected non-invasively in various intact tissues, including the bone marrow (BM), for extensive periods of time following transplantation. (jove.com)
The diagnosis of CLL is based on the demonstration of an abnormal population of B lymphocytes in the blood, bone marrow, or tissues that display an unusual but characteristic pattern of molecules on the cell surface. (wikipedia.org)
Gene therapy is a relatively new concept in the field of SCID. (wikipedia.org)
Gene therapy aims to correct the underlying genetic abnormality in SCID. (wikipedia.org)
Stem cells are taken from an affected child's blood or bone marrow. (wikipedia.org)
Whether the condition involves red or white blood cells, platelets or bone marrow, our expert hematology team provides the most advanced treatments around for children. (wolfsonchildrens.com)
this disorder is a form of plasma cell dyscrasia in which no myeloma protein is detected in serum or urine (at least as determined by conventional laboratory methods) of individuals who have clear evidence of an increase in clonal bone marrow plasma cells and/or evidence of clonal plasma cell-mediated tissue injury (e.g. plasmacytoma tumors). (wikipedia.org)
Enzyme replacement therapy is available to treat mainly Fabry disease and Gaucher disease, and people with these types of sphingolipidoses may live well into adulthood. (wikipedia.org)
Since the implementation of enzyme replacement therapy for Hunter syndrome, lifespans for those without mental handicaps are expected to lengthen since their physical disease appears to improve or stabilize with such treatment. (wikipedia.org)
Most advanced surgery and radiation therapy for all types of malignancies. (fnkc.ru)
Improvement of radiation therapy results in children. (fnkc.ru)
Prof. Steward is a Consultant in bone marrow transplantation at the Royal Hospital for Children, Bristol, England. (barthsyndrome.org)
The Blood and Marrow Transplantation Center at Wolfson Children's Hospital, a collaboration with Nemours Children's Specialty Care Jacksonville and Mayo Clinic, brings children from all over the world to receive care. (wolfsonchildrens.com)
citation needed] A variation on the Carticel technique, called matrix-associated autologous chondrocyte transplantation (MACT), grows the patient's cells in a 3D matrix of resorbable tissue which is implanted via an open or arthroscopic procedure. (wikipedia.org)
significantly
Conclusions- A combination of AM infusion and MNC transplantation caused significantly greater improvement in hindlimb ischemia than MNC transplantation alone. (ahajournals.org)
The hematopoietic cells are able to go to the bone marrow through tracking mechanisms. (wikipedia.org)
Diamond-Blackfan anemia is characterized by normocytic or macrocytic anemia (low red blood cell counts) with decreased erythroid progenitor cells in the bone marrow. (wikipedia.org)
Development of the new methods of treatment of children with acquired and inherited bone marrow failures. (fnkc.ru)
Autologous matrix-induced chondrogenesis, which is also known as AMIC, is a biological treatment option for articular cartilage damage bone marrow stimulating technique in combination with a collagen membrane. (wikipedia.org)
While the initial treatment is to address the underlying disease, ultimately the therapy is directed to the management of portal hypertension. (wikipedia.org)
3. Primary bone sarcomas. (careacross.com)
Methods and Results- Immediately after hindlimb ischemia was created, rats were randomized to receive AM infusion plus bone marrow-derived mononuclear cell (MNC) transplantation (AM+MNC group), AM infusion alone (AM group), MNC transplantation alone (MNC group), or vehicle infusion (control group). (ahajournals.org)
This is in contrast to Shwachman-Bodian-Diamond syndrome, in which the bone marrow defect results primarily in neutropenia, and Fanconi anemia, where all cell lines are affected resulting in pancytopenia. (wikipedia.org)
CLL results in the build up of B cell lymphocytes in the bone marrow, lymph nodes, and blood. (wikipedia.org)
In many cases, spinal cord injuries require substantial, long-term physical and occupational therapy in rehabilitation, especially if they interfere with activities of daily living. (wikipedia.org)
Thus, the purposes of the present study were (1) to investigate whether local infusion of AM enhances the angiogenic potency of MNC transplantation in a rat model of hindlimb ischemia and (2) to investigate the effects of AM on the survival, adhesion, and differentiation of transplanted MNCs. (ahajournals.org)
The drug was noted to increase the risk of veno-occlusive disease in the absence of bone marrow transplantation. (wikipedia.org)
This protocol resulted in the creation of 4 groups: (1) AM infusion plus MNC transplantation (AM+MNC group, n=10), (2) AM infusion plus PBS injection (AM group, n=10), (3) vehicle infusion plus MNC transplantation (MNC group, n=10), and (4) vehicle infusion plus PBS injection (control group, n=10). (ahajournals.org)
Rose J. P. and Weis, J., Sound meditation in oncological rehabilitation: a pilot study of a receptive music therapy group using the monochord. (wikipedia.org)
Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. (wikipedia.org)
The most common and frequently used combination or synthesis comprises meditation music and receptive music therapy, guided imagery, relaxation, some form of meditative practice, and journaling. (wikipedia.org)
Bone marrow product is infused through a central vein over a period of several hours. (wikipedia.org)
mesenchymal stem
The study was designed to investigate whether ultrasound-mediated microbubble destruction can enhance the transplantation of bone marrow mesenchymal stem cells (BMSCs) for myocardial infarction therapy, twenty myocardial infarction pigs were assigned into the ultrasound microbubble destruction group (n=12, Sonovue were infused into coronary artery with ultrasonic radiation, then BMSCs were injected into infarction region) and the cell control group (n=8, only subjected to BMSCs treatment). (omicsonline.org)
In vivo implant of the scaffolds with or without mesenchymal stem cells (MSCs) showed that appropriate positions for transplantation were the mesentery and liver and the scaffolds could induce donor-loaded MSCs or host migrating cells to differentiate to the cells with phenotype of the sertoli- and leydig-like cells. (biomedcentral.com)
Allogenic bone-marrow-derived mesenchymal stem cells transplantation as a novel therapy for systemic lupus erythematosus. (gulfcoaststemcell.com)
Bone-marrow-derived mesenchymal stem cells (BMMSC) are multipotent non-hematopoietic progenitor cells that are being explored as a promising new treatment for tissue regeneration. (gulfcoaststemcell.com)
allogeneic stem cell trans
Determine if a nonmyeloablative regimen comprising cyclophosphamide, fludarabine, and radiotherapy followed by cyclosporine and mycophenolate mofetil provides a prompt and durable donor engraftment in patients with hematologic malignancies or kidney cancer who are undergoing allogeneic stem cell transplantation. (careacross.com)
undergo
OUTLINE: Patients undergo harvesting of autologous bone marrow. (clinicaltrials.gov)
Patients undergo sargramostim (GM-CSF)-treated autologous bone marrow transplantation on day 0. (clinicaltrials.gov)
Patients with marrow involvement who achieve marrow complete response after cytoreduction undergo harvest of bone marrow before IFRT. (clinicaltrials.gov)
Patients with involved sites 2 cm or greater in diameter at evaluation and previously unirradiated active disease sites, at least 90% of which can be treated with IFRT, undergo IFRT 5 days a week for 2 weeks beginning after cytoreduction and 3-5 weeks after harvest of bone marrow. (clinicaltrials.gov)
Eligible patients with residual disease at 3 months after transplantation undergo involved field 'boost' irradiation to sites of residual disease. (clinicaltrials.gov)
Arm II: Patients undergo low-energy laser therapy with invisible infra-red light (780 nm) daily on the same schedule as in arm I. Arm III: Patients undergo sham laser therapy daily on the same schedule as in arm I. Patients are followed on days 3, 7, 10, 14, 18, 21, and 24. (knowcancer.com)
Allogeneic peripheral blood stem cell transplantation (PBSCT): Patients undergo allogeneic PBSCT on day 0. (careacross.com)
When patients with blood cancers (leukemia and lymphoma) receive high dose chemotherapy and radiation therapy to undergo bone marrow transplantation, they usually get severe oral mucositis. (wikipedia.org)
total body irradi
PURPOSE: Phase II trial to study the effectiveness of high-dose etoposide and cyclophosphamide plus total-body irradiation followed by bone marrow transplantation in treating patients who have relapsed or refractory non-Hodgkin's lymphoma. (clinicaltrials.gov)
OBJECTIVES: I. Determine the toxicity and activity of cyclophosphamide, etoposide, total body irradiation, and autologous bone marrow transplantation in patients with relapsed or refractory non-Hodgkin's lymphoma. (clinicaltrials.gov)
We retrospectively compared the outcomes of children with acquired severe aplastic anemia who received immunosuppressive therapy within prospective trials conducted by the Japanese Childhood Aplastic Anemia Study Group or who underwent bone marrow transplantation from an HLA-matched family donor registered in the Japanese Society for Hematopoietic Cell Transplantation Registry. (haematologica.org)
Hematopoietic cell transplantation (HCT) is a procedure by which a patient's missing or diseased blood forming stem cells are replaced by cells from a healthy donor. (cancertherapyadvisor.com)
Oral Mucositis
OBJECTIVES: I. Determine whether low-energy laser therapy can prevent oral mucositis in patients undergoing bone marrow transplantation. (knowcancer.com)
Radiation therapy uses high-energy x-rays to damage cancer cells. (clinicaltrials.gov)
Bone marrow transplantation may allow doctors to give higher doses of radiation therapy and chemotherapy and kill more cancer cells. (clinicaltrials.gov)
Radiation enteritis is a functional disorder of the large and small bowel that occurs during or after a course of radiation therapy to the abdomen, pelvis, or rectum. (cancer.gov)
Some also may have radiation therapy and/or bone marrow transplantation. (medicinenet.com)
Symptoms of all forms of leukemia are related to the proliferation of abnormal blood cells and replacement of the bone marrow by the cancerous cells. (medicinenet.com)
Natural killer cells and lymphocytes increase in women with breast cancer following massage therapy. (nih.gov)
PURPOSE: Phase II trial to study the effectiveness of bone marrow transplantation, chemotherapy, and biological therapy in treating patients who have chronic myeloid leukemia. (clinicaltrials.gov)
OBJECTIVES: I. Determine the one year event-free survival in patients with chronic phase chronic myeloid leukemia receiving sargramostim (GM-CSF)-treated autologous bone marrow transplantation followed by GM-CSF and interferon alfa. (clinicaltrials.gov)
New bone formation was observed in all patients. (ovid.com)
This combined therapy is noninvasive, feasible, and joint-preserving in most ONFH patients. (ovid.com)
Determine the safety of this nonmyeloablative transplantation regimen in these patients. (careacross.com)
Determine the antineoplastic potency of nonmyeloablative stem cell transplantation in patients treated with this regimen. (careacross.com)
Unrelated donor recipients who have received only 1 induction course for the treatment of acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or blastic phase chronic myelogenous leukemia (CML) NOTE: **Patients who underwent prior autologous stem cell transplantation in the past year do not receive ATG. (careacross.com)
Daily area under the curve (AUC) where AUC is based on average of 5 most severe symptoms (pain, fatigue, bone aches, numbness, disturbed sleep) being experienced by MM patients as measured by MDASI-MM, a multiple-symptom measure of cancer-related symptoms rate severity of physical, affective, and cognitive symptoms on 0-10 numeric scales, ranging from 0 'not present' to 10 'as bad as you can imagine. (clinicaltrials.gov)
Effects of a full-body massage on pain intensity, anxiety, and physiological relaxation in Taiwanese patients with metastatic bone pain: a pilot study. (nih.gov)
Massage therapy for patients undergoing autologous bone marrow transplantation. (nih.gov)
Breast cancer patients have improved immune and neuroendocrine functions following massage therapy. (nih.gov)
There is a lack of efficacious treatment options for patients with relapsed/refractory diffuse large cell Non-Hodgkin's lymphoma (DLCL) who are not appropriate candidates for stem cell transplantation. (clinicaltrials.gov)
DLCL is a relatively radiosensitive disease and patients with DLCL have been reported to respond to anti-CD20 monoclonal antibody (MAB) therapy. (clinicaltrials.gov)
Furthermore, chaperone therapy, a technique used to stabilize the defective enzymes produced by patients, is being examined for certain of these disorders. (wikipedia.org)
In 2006 Eaves retired as required by provincial law at that time, becoming Professor Emeritus of Hematology and spending more time on several companies he founded to further the fields of cellular therapy and regenerative medicine - STEMCELL Technologies, STEMSOFT Software Inc. and Malachite Management Inc. These companies continue to grow under his leadership and by 2016, STEMCELL had over 900 employees making Canada's largest biotechnology company. (wikipedia.org)
Clinical and plain radiographic evaluations were performed before transplantation and at the most recent follow-up. (ovid.com)
Stem cell therapy [ 1 ] and tissue engineering [ 2 ] are two new approaches to improve the male fertility. (biomedcentral.com)
The Cell Surgical Network is not offering stem cell therapy as a cure for any condition, disease, or injury. (gulfcoaststemcell.com)
ATTENTION: If you have ANY concern with our autologous stem cell therapy product, methods, website, or technique and think we may be violating any U.S. law, please contact us so that we can investigate the matter or concern immediately. (gulfcoaststemcell.com)
We describe a novel, combined approach to the treatment of osteonecrosis of the femoral head (ONFH) based on concentrated autologous bone marrow aspirates (CABMAT) and low-intensity pulsed ultrasound (LIPUS). (ovid.com)
Our study first time testifies in pig models that ultrasound-mediated microbubble destruction promotes BMSC transplantation for myocardial infarction therapy. (omicsonline.org)
Autologous bone marrow is harvested before cytoreduction or involved field radiotherapy (IFRT). (clinicaltrials.gov)
Pilot study evaluating the effect of massage therapy on stress, anxiety and aggression in a young adult psychiatric inpatient unit. (nih.gov)
Large numbers of leukemia cells accumulate very quickly in the blood and bone marrow, leading to symptoms such as tiredness , easy bruising , and susceptibility to infections. (medicinenet.com)
RATIONALE: Biological therapy may increase the number of immune cells found in bone marrow and may help a person's immune system recover from the side effects of the chemotherapy used in treating chronic myeloid leukemia. (clinicaltrials.gov)
Since these results are not satisfying, it is of great importance to look for novel and effective approaches to increase the efficiency of stem cell transplantation. (omicsonline.org)
Seven years after BMT, thrombocytopenia developed and marrow examination confirmed t-MDS, with a characteristic karyotype 46.XX,inv(3)(q21:q26), del(5)(q13),add(17)(p11). (hku.hk)
Fatigue, weight loss, and bone or joint pain are other potential symptoms. (medicinenet.com)
The reader is advised to consult with a physician or other medical professional and to check product information (including packaging inserts) for changes and new information regarding dosage, precautions, and contra indication before administering any drug, herb, supplement, compound, therapy or treatment discussed herein. (cancerconnect.com)
Massage therapy for the treatment of depression: a systematic review. (nih.gov)
In addition, substrate reduction therapy, a method used to decrease the production of storage material, is currently being evaluated for some of these diseases. (wikipedia.org)
Intra-coronary artery transplantation achieves the second highest efficiency, usually 1% to 2%, although 10% has also been reported [ 4 ]. (omicsonline.org)
A meta-analysis of massage therapy research. (nih.gov)
CSN does not claim that any applications, or potential applications, using these autologous stem cell therapies are approved by the FDA, or are even effective. (gulfcoaststemcell.com)
Must be qualified and have signed consent to receive lenalidomide for maintenance therapy for MM. (clinicaltrials.gov)
Our aim is to discuss recent progress in understanding the role of malfunctioning BMMSC in etiopathogenesis of SLE and to explore allogenic BMMSC transplantation as a potential therapy for SLE. (gulfcoaststemcell.com)
Must have negative pregnancy test before signing consent for MM therapy. (clinicaltrials.gov)


text:
Ardu Maser
Ardú - Maser
Washington Street West
www.maserart.com/
Having created artwork since 1995, over the last 25 years, Maser has earned much respect professionally and has generated a large and dedicated following in Ireland and abroad – through his seamlessly imaginative and unique graphic style.
Having become internationally recognised for his expansive repertoire of contemporary visual art, Maser's artistic practice includes works on canvas, sculptures, prints, immersive installations, interactive exhibitions and exquisite large-scale murals.
His unique, artistic style draws upon numerous influences including optical art and mid-century art, and is regularly complemented with bold colours, pattern and text. Maser is ambitious and is unafraid to experiment with any artistic format.
Maser boasts an impressive list of exhibitions in high-end art galleries and has been commissioned to create original artwork by many prestigious arts organisations including, Art On Paper (USA), Lazarides (UK), the National Gallery of Ireland, the National Library of Ireland, Tandem Press(USA) and Graphic Print Studio. He also collaborated with President Michael D Higgins on a series of bespoke limited edition prints in 2018.
Ardú, featuring seven extraordinary murals from seven of Ireland's top street artists, arrived in Cork October 2020 injecting a burst of colour, vibrancy, and life into Cork city in lockdown - uniting the Leeside community through art, lifting its creative and community spirit at a time when it needed it most.
Ardú – the Irish for 'Rise' – bases itself on a theme of nostalgia and celebration. Cork City rose from the ashes 100 years ago following the Burning of Cork, and now faces the challenge to rise again.
At a time when we face shared and personal challenges, each of our artist's murals are a rallying cry to the city – a call to remember that we have been through terrible times before and we rose up. We can do it again. Join us for a celebration of Cork city's traditions, history, and resolution.
Hayfield Manor Hotel
Maria Ville House
Cork Airport Hotel
Meade's Wine Bar
Callanans

redpajama_set_name: RedPajamaCommonCrawl


text:
Top 10 Tuesday: Most Anticipated Releases for the Second Half of 2020
June 30, 2020 June 30, 2020 M.T.Wilson @ The Last Book on the Left13 Comments
There are so many books coming out this year that sound amazing! Here are ten of my most anticipated releases for the second half of 2020.
Top 10 Tuesday was originally created by The Broke and the Bookish, but has now moved to That Artsy Reader Girl. If you're interested in taking part click here.
Blood & Honey by Shelby Mahurin
The hotly anticipated sequel to the New York Times and IndieBound bestseller Serpent & Dove—packed with even steamier romance and darker magic—is perfect for fans of Sarah J. Maas.
After narrowly escaping death at the hands of the Dames Blanches, Lou, Reid, Coco, and Ansel are on the run from coven, kingdom, and church—fugitives with nowhere to hide.
To elude the scores of witches and throngs of chasseurs at their heels, Lou and Reid need allies. Strong ones. But protection comes at a price, and the group is forced to embark on separate quests to build their forces. As Lou and Reid try to close the widening rift between them, the dastardly Morgane baits them in a lethal game of cat and mouse that threatens to destroy something worth more than any coven.
I absolutely loved Serpent & Dove so I am so excited for the sequel which is coming out in September!
Crownchasers by Rebecca Coffindaffer
A deadly competition for the throne will determine more than just the fate of the empire in this riveting duology opener, perfect for fans of The Hunger Games, Aurora Rising, and Three Dark Crowns.
Alyssa Farshot has spent her whole life trying to outrun her family legacy. Her mother sacrificed everything to bring peace to the quadrant, and her uncle has successfully ruled as emperor for decades. But the last thing Alyssa wants is to follow in their footsteps as the next in line for the throne. Why would she choose to be trapped in a palace when she could be having wild adventures exploring a thousand-and-one planets in her own ship?
But when Alyssa's uncle becomes gravely ill, his dying wish surprises the entire galaxy. Instead of naming her as his successor, he calls for a crownchase, the first in seven centuries. Representatives from each of the empire's prime families—including Alyssa—are thrown into a race to find the royal seal, which has been hidden somewhere in the empire. The first to find the seal wins the throne.
Alyssa's experience as an explorer makes her the favorite to win the crown she never wanted. And though she doesn't want to be empress, her duty to her uncle compels her to participate in this one last epic adventure. But when the chase turns deadly, it's clear that more than just the fate of the empire is at stake. Alyssa is on her most important quest yet—and only time will tell if she'll survive it.
Sci-fi set in space in one of my favourite kinds of books and the synopsis for this one sounds awesome.
Star Daughter by Shveta Thakrar
This gorgeously imagined YA debut blends shades of Neil Gaiman's Stardust and a breathtaking landscape of Hindu mythology into a radiant contemporary fantasy.
The daughter of a star and a mortal, Sheetal is used to keeping secrets. Pretending to be "normal." But when an accidental flare of her starfire puts her human father in the hospital, Sheetal needs a full star's help to heal him. A star like her mother, who returned to the sky long ago.
Sheetal's quest to save her father will take her to a celestial court of shining wonders and dark shadows, where she must take the stage as her family's champion in a competition to decide the next ruling house of the heavens–and win, or risk never returning to Earth at all.
Brimming with celestial intrigue, this sparkling YA debut is perfect for fans of Roshani Chokshi and Laini Taylor.
I can't lie, it was the stunning cover that drew me to this book initially. I haven't read much contemporary fantasy so I was excited when I read the description for this one!
Cinderella is Dead by Kalynn Bayron
It's 200 years since Cinderella found her prince, but the fairytale is over.
Sophia knows the story though, off by heart. Because every girl has to recite it daily, from when she's tiny until the night she's sent to the royal ball for choosing. And every girl knows that she has only one chance. For the lives of those not chosen by a man at the ball . are forfeit.
But Sophia doesn't want to be chosen – she's in love with her best friend, Erin, and hates the idea of being traded like cattle. And when Sophia's night at the ball goes horribly wrong, she must run for her life. Alone and terrified, she finds herself hiding in Cinderella's tomb. And there she meets someone who will show her that she has the power to remake her world.
The title for this book makes it quite clear this is a Cinderella retelling! I love retellings and from the description this sounds like an interesting take.
The Space Between Worlds Micaiah Johnson
CARA IS DEAD ON THREE HUNDRED AND SEVENTY-FOUR WORLDS.
The multiverse business is booming, but there's just one catch: no one can visit a world where their counterpart is still alive.
Enter Cara, whose parallel selves happen to be exceptionally good at dying–from diseases, from turf wars, from vendettas they couldn't outrun.
But on this earth, Cara's survived. And she's reaping the benefits, thanks to the well-heeled Wiley City scientists who ID'd her as an outlier and plucked her from the dirt. Now she's got a new job collecting offworld data, a path to citizenship, and a near-perfect Wiley City accent. Now she can pretend she's always lived in the city she grew up staring at from the outside, even if she feels like a fraud on either side of its walls.
But when one of her eight remaining doppelgangers dies under mysterious circumstances, Cara is plunged into a new world with an old secret. What she discovers will connect her past and future in ways she never could have imagined–and reveal her own role in a plot that endangers not just her world, but the entire multiverse.
Multiverses and doppelgangers? I'm in! I think the blurb speaks for itself here.
A Deadly Education by Naomi Novik
Enter a school of magic unlike any you have ever encountered. There are no teachers, no holidays, friendships are purely strategic, and the odds of survival are never equal. Once you're inside, there are only two ways out: you graduate or you die.
El Higgins is uniquely prepared for the school's many dangers. She may be without allies, but she possesses a dark power strong enough to level mountains and wipe out untold millions – never mind easily destroy the countless monsters that prowl the school.
Except, she might accidentally kill all the other students, too. So El is trying her hardest not to use it… that is, unless she has no other choice.
Wry, witty, endlessly inventive, and mordantly funny – yet with a true depth and fierce justice at its heart – this enchanting novel reminds us that there are far more important things than mere survival.
I've somehow managed to not read any of Naomi Novik's books yet. I know. I know. I need to remedy that.
Filled with mystery and an intriguingly rich magic system, Tracy Deonn's YA contemporary fantasy Legendborn offers the dark allure of City of Bones with a modern-day twist on a classic legend and a lot of Southern Black Girl Magic.
After her mother dies in an accident, sixteen-year-old Bree Matthews wants nothing to do with her previous life, family memories, or her childhood home. A residential program for bright high schoolers at a local university seems like the perfect escape—until Bree witnesses a magical attack her very first night on campus.
A flying demon feeding on human energies.
A secret society of so called "Legendborn" students that hunt the creatures down.
And a teenage mage who calls himself a "Merlin" and who attempts—and fails—to wipe Bree's memory of everything she saw.
The mage's failure reveals Bree's own, unique magic and unlocks a buried memory with a hidden connection: the night her mother died, another Merlin was at the hospital. Now that she knows there's more to her mother's death than what's on the police report, Bree will do whatever it takes to find out the truth, even if that means infiltrating the Legendborn by becoming one of their initiates. But when the Legendborn reveal themselves as the descendants of King Arthur and his knights and explain that a magical war is coming, Bree has to decide how far she'll go for the truth and whether she should use her magic to take the society down—or join the fight.
This sounds like City of Bones meets King Arthur with Black Girl Magic and wow that's an amazing combination.
These Violent Delights by Chloe Gong
Perfect for fans of The Last Magician and Descendant of the Crane, this heart-stopping debut is an imaginative Romeo and Juliet retelling set in 1920s Shanghai, with rival gangs and a monster in the depths of the Huangpu River.
The year is 1926, and Shanghai hums to the tune of debauchery.
A blood feud between two gangs runs the streets red, leaving the city helpless in the grip of chaos. At the heart of it all is eighteen-year-old Juliette Cai, a former flapper who has returned to assume her role as the proud heir of the Scarlet Gang—a network of criminals far above the law. Their only rivals in power are the White Flowers, who have fought the Scarlets for generations. And behind every move is their heir, Roma Montagov, Juliette's first love…and first betrayal.
But when gangsters on both sides show signs of instability culminating in clawing their own throats out, the people start to whisper. Of a contagion, a madness. Of a monster in the shadows. As the deaths stack up, Juliette and Roma must set their guns—and grudges—aside and work together, for if they can't stop this mayhem, then there will be no city left for either to rule.
I've not actually read a Romeo and Juliet retelling before, though I know there are a few out there, but this one caught my eye with that gorgeous cover and intriguing description.
The Invisible Life of Addie Larue by V. E. Schwab
France, 1714: in a moment of desperation, a young woman makes a Faustian bargain to live forever-and is cursed to be forgotten by everyone she meets.
Thus begins the extraordinary life of Addie LaRue, and a dazzling adventure that will play out across centuries and continents, across history and art, as a young woman learns how far she will go to leave her mark on the world.
But everything changes when, after nearly 300 years, Addie stumbles across a young man in a hidden bookstore, and he remembers her name.
I still haven't read any V. E. Schwab books… This one has an interesting premise and seems close to the author's heart from what she has shared on Twitter. I really need to read some of her books!
Skyhunter by Marie Lu
In Skyhunter, a novel laced with adrenaline and filled with nonstop action, #1 New York Times bestselling author Marie Lu creates an immersive world broken by war where the only hope against overwhelming evil lies with a team of young warriors willing to sacrifice everything to save what they love.
The Karensa Federation has conquered a dozen countries, leaving Mara as one of the last free nations in the world. Refugees flee to its borders to escape a fate worse than death―transformation into mutant war beasts known as Ghosts, creatures the Federation then sends to attack Mara.
The legendary Strikers, Mara's elite fighting force, are trained to stop these monsters. But as the number of Ghosts grows and Karensa closes in, defeat seems inevitable.
Still, one Striker refuses to give up hope.
Robbed of her voice and home, Talin Kanami knows firsthand the brutality of the Federation. Their cruelty forced her and her mother to seek asylum in a country that finds their people repugnant. She finds comfort only with a handful of fellow Strikers who have pledged their lives to one another, soldiers determined to push Karensa back at all costs.
After another devastating battle, Mara seems ready to fall. But when a mysterious prisoner is brought from the front, Talin senses there's more to him than meets the eye. Is he a spy from the Federation? Or could he be the weapon that will save them all?
Even though I've only read two Marie Lu books so far, I absolutely loved them (first two books in the Young Elites series) so I'm totally up for reading more of her books.
What are your most anticipated releases for the second half of 2020? Are there any we have in common? Or do you have some recommendations for me!
2020 releases, anticipated reads, books, fantasy, reading, sci-fi, Top 10, Top 10 Tuesday, upcoming releases, young adult
June 2020 Wrap Up
Let's Talk Bookish: What Makes a Book YA?
13 thoughts on "Top 10 Tuesday: Most Anticipated Releases for the Second Half of 2020"
Cinderella Is Dead has been such a popular choice this week. Y'all might just convince me to add it to my TBR. :D
My TTT .
M.T.Wilson says:
Yes I've seen it on a lot of lists too! Fingers crossed it will be good!
susanblogginboutbooks says:
CINDERELLA IS DEAD sounds so intriguing! I hope you love it and all your other picks.
It does sound intriguing, hopefully it will be a good read!
So many good books still to come! I can't wait for A deadly education and Addie La Rue!
My post!
Yes I think 2020 will be a good year for books (if nothing else haha)
At least there is that haha!
The invisible life of Addie Larue is on my tbr. The Cinderella one sounds good too. Thanks for pointing it out!
They both look good! Glad you discovered a new book!
Rine says:
I'm really interested in Cinderella is Dead – love having a weird twist on a retelling. I am also interested in A Deadly Education but I've never picked anything up by Naomi Novik before so hoping I actually do get to this. I'm also looking forward to Black Sun by Rebecca Roanhorse which is a fantasy that I think takes inspiration from South American culture. The cover is absolutely stunning so just grabbed my attention.
Also the cover for The Invisible Life of Addie Larue is stunning.
Yes I really want to finally read a Naomi Novik book, I've seen so much about her works. I've not heard of Black Sun, I'll have to check it out.
Crownchasers is going on my tbr. Thanks for the introduction. :)
It looks amazing, great to hear I introduced you to a new read! :)


text:
Q: Using ranger method caret train function I am having trouble using ranger with caret to predict probabilities. Here is my code:
model <- train(Species ~ .,
               data = iris,
               method = "ranger",
               probability = TRUE)

This returns the following error(s), warning(s), and message(s).
## Something is wrong; all the Accuracy metric values are missing:
##    Accuracy       Kappa
## Min.   : NA   Min.   : NA
## 1st Qu.: NA   1st Qu.: NA
## Median : NA   Median : NA
## Mean   :NaN   Mean   :NaN
## 3rd Qu.: NA   3rd Qu.: NA
## Max.   : NA   Max.   : NA
## NA's   :6     NA's   :6
## Error: Stopping
## In addition: There were 50 or more warnings (use warnings() to see the first 50)

Running it outside of caret works though.
ranger(Species ~ ., data = iris, probability = TRUE)

A: Put classProbs inside trControl as in:
model <- train(
  Species  ~ .
  ,data = iris
  ,method = "ranger"
  ,trControl = trainControl(classProbs=TRUE)
)

redpajama_set_name: RedPajamaStackExchange


text:
What in the world was Metropolitan Correctional Center up to?
The absurdity of Jeffrey Epstein's last days in this mortal realm may never be fully understood, but every morsel of information that we've been given indicates that the accused child sex trafficker did not receive typical treatment while imprisoned.
The medical examiner responsible for Epstein's autopsy rushed out a hurried and frantic declaration of "suicide" on Friday – a statement that has been deemed questionable by online conspiracy theorists.
This explanation stands alone, obviously, but the evidence pointing to Epstein's controversial treatment in Metropolitan Correctional Center continues to pile up.
Trending: Violent Bernie Bros Arrested Just Days Before Hidden Camera Kerfuffle
Jeffrey Epstein spent at least two hours locked up alone with a mystery woman — possibly part of his legal team — just a day after he was taken off suicide watch at the Metropolitan Correctional Center, according to a new report.
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A visiting attorney, who asked that his name not be used, told Forbes Thursday that he saw the young woman with Epstein on July 30, when the disgraced financier was transferred into the facility's Special Housing Unit.
"The optics were startling," the attorney told the outlet. "Because she was young. And pretty."
While it is entirely possible that this visitor was simply a member of Epstein's legal team, at least one witness believed that the extraordinary circumstances were worth noting.
"I think she was there just to babysit him, and keep him out of his cell, and just keep him company for eight hours a day," he added. "Which is not supposed to be the way it works."
Attorneys who hoped to utilize the space to confer with their clients were irked at the prolonged visits that Epstein experienced, as this special treatment prohibited them from continuing their work.
In this article:Featured, Jeffrey Epstein, pedophilia, sex trafficking, suicide
Just weeks after Russia nuke treaty rescinded, Pentagon pops off previously banned missile
China furious with White House after sale of military assets to Asian nation
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Trending Now on Liberty Hub
There's a New 2020 Democratic Frontrunner, According to Donald Trump


Empty Tin 400g - Pour Cirépil Beads into tin and place into heater well.
Empty tins are designed to fit standard 3.75", 400 gram wax warmers.
Tin is 2-1/2 inches deep and 3-3/4" in diameter.
Received can but it was really dented up...paid more for shipping than for the product!
Those empty tins can take a battering in shipping because they are empty and sealed to make sure they are sanitary. We do our best to pack them in a way we have found works most of the time... but dents can happen. Please contact our offices 888-561-8068 and we will replace it for you.
I have not received any of my order yet .
It looks like your order placed on 1/15 was shipped via UPS the same day. It was delivered on 1/23. This is pretty typical of UPS cross country deliveries and a key reason we ship anything we can via Priority Mail. We hope you are enjoying your products.
I like that I can get inexpensive empty tin cups for my new wax.


text:
Butch Pal For The Straight Gal
by Ally Johnson
Ally Johnson
Comedy, Reality-TV
We've seen two installments of Queer Eye For The Straight Guy in the last 15 years. How many lesbian equivalents have we seen?? EXACTLY. Help us raise funds for the first episode of Butch Pal For The Straight Gal so we can show the world that ALL gays can change the lives of wayward straights.
232 supporters
232 supporters, 298 followers
Butch Pal For Straight Gal presents a fun representation of the lesbian lifestyle and shows how people's lives can be made better with a little lesbian fairy dust sprinkled into it. We aim to inspire body positivity, female inner beauty and prove that a little flannel goes a long way.
Earlier this year, the reboot of Queer Eye came out on Netflix. Two seasons have already been released. While I'm all for more LGBT content, I couldn't help but be frustrated that this show was already getting a remount when the lesbian version never even existed. I started thinking, 'What would happen if five lesbians gave a straight girl a makeover? Would she just end up covered in flannel and cat hair? Would a rugged day-hike be involved? Would she get really good at making vegan tacos?' These questions had to be answered, so I teamed up with Rob, a guy I dated for two weeks in high school, and we decided to make it happen.
Rob & I are ready to take on the challenge by creating Butch Pal For The Straight Gal. Five experienced lesbians who call themselves the Fish 5 will give wayward straight women lez-tastic makeovers (or make-unders), which may or may not include fedoras and Birkenstocks. While this series is at heart a comedy, it presents a deeper message about women and how they present themselves in today's social media-driven society. It pokes fun at stereotypes and gives you a laugh, but the overall message is one of inclusivity and self-love. And what's gayer than that?!
<--- lesbians, we can't live off these forever
The first episode is written and ready to shoot, but we need your help to make this pilot the best it can possibly be. When we reach our fundraising goal we will not only make this hilarious & heartfelt episode happen, we will pitch it to networks, websites and LGBTQIA groups looking for funny and original content. The more you donate, the more episodes we film. We ultimately want this to be full season of lesbian hilarity with season two not far behind. With your help, Butch Pal For The Straight Gal can be the next show in your Netflix queue.
Lesbian is still the #1 searched porn term worldwide. Just sayin'....there's an audience out there. And it's not just pervy straight dudes. I promise. Lesbians are worth watching, and we intend to prove it with Butch Pal. Now, more than ever, it's time to send the message that women don't have to vacuum their lips through a shotglass to be hot. Can you believe??
We believe. And with your help our belief will become reality. It's Pride month, and what better way to show your support than by funding a project that will entertain you for years to come?? Help fund the lesbian Queer Eye today!
Social Media Shoutout
Thank you for contributing! You've earned yourself a personal shoutout on the social media platform of your choice. We might even throw in a rainbow emoji.
Be the first to watch the pilot!
Ok, you're invested. You also just paid to feed some of our hardworking actors & crew members. You're feeling pretty special aren't you? Well, how about getting sent a personal link to the first finished episode so you can see it before it's released to the public? Happy now?!
(Also includes the Social Media Shoutout perk!)
Pilot + Blooper Reel
What's funnier than the Flish 5? Wait, did I say "flish"? That's a blooper! And you'll be the first to see all the hilarity that happens that doesn't make the original cut.
(Also includes the previous perks!)
Ask a Lesbian - Advice Column
Need advice for a date? Spurned by a lover? Want to know great hiking locations? For your donation of $50 you'll get all the above plus we'll give you our secret email address so you can ask a lesbian anything that troubles you. And we might even post it on our social media page! Don't worry, you'll be anonymous!
Claimed: 15 of 200
A Personal Thank You In The Credits
You're a star, and as a star you should be awknowledged! You'll get all of the above plus a personal thank you in the credits of the episode!
Fish 5 T-Shirt
So you're invested and feeling pretty good, but if you want to be a true vegan you know you have to start telling people about it. With your donation of $100 you'll get all the above (excluding anything of sold out quantities) plus your own cast names t-shirt to prove to everyone you mean it.
Signed Script
Ever wondered how much is improv and how much is the script? Well for you donation of $250 you'll get to solve that great question. You'll get all the above (excluding anything of sold out quantities) and get to take home your own piece of the show signed by the cast and crew!
Claimed: 6 of 200
Associate Producer Credit
You like us and you want to make this happen. That's thinking like a producer, so you should be one. You'll get all the above (excluding anything of sold out quantities) and you'll be added to the pilot's credits as Associate Producer and included when it goes up on IMDB!
Your Very Own Lesbian Viewing Party
Who doesn't want a bunch of lesbians in their living room? If you're in the Los Angeles area (or you can get in the Los Angeles area) Members of The Fish 5 will pay you a special visit and hang for a special VIP viewing of Butch Pal or any LGBT series or movie of your choice. Want to binge watch the L Word? We're always down.
(Also includes above perks excluding anything of sold out quantities)
You're moving up in the world and I like the way you think. You're ready for a promtion and you're gonna get it! You'll get all the above (excluding anything of sold out quantities or Associate Producer) and you'll be added to the pilot's credits as Co-Producer and included when it goes up on IMDB!
A Personalized Lez-tastic Makeover
Are you a straight guy or gal in need of a lesbian makeover? Or maybe there's someone in your life you'd like to nominate? If you're in the Los Angeles area (or you can get in the Los Angeles area) Members of The Fish 5 will pay you a personal visit and give you a consultation on how you can improve your life for the better. Whether it's cuisine, grooming, fashion, design or culture, the Fish 5 are here to help!
When you set your mind on a project, nothing will stop you. This project is happening and you're making sure of it! No amount of thanks can thank you. You're the star above stars. The EP! You'll get all the above (excluding anything of sold out quantities, Associate, or Co-Producer) and you'll be added to the pilot's credits as Executive Producer and included when it goes up on IMDB!
"We'll be really careful" doesn't work when renting equipment and shooting locations.
Covers 3 days of shooting
Food & Bev for Our Team
Make sure our team is fed & hydrated!
Our Cast
Too often actors are asked to work for free. Our performers deserve to be compensated!
1st Assistant Camera
Who wouldn't want this guy on set?
Sound Operator / Mixer
Sound Operator and Mixer for 3 days of shooting
This film won't be very good if no one can see us.
Production assistance for the entire shoot!
Editing is a long & grueling process. Let's get a great editor to make this into a masterpiece!
Make sure our film has the right pop & pazzazz after filming
We have a flannel on-hand, but we'll need some costumes.
Everyone loves props. Including us.
All equipment rentals needed for shooting
Increase awareness for our series with a professional screening in LA
Misc Extra Costs
Unexpected expenses will most definitely come up. This covers the unexpected.
Funds for our INCREDIBLE director!
You're now following Butch Pal For The Straight Gal! Hungry for more great series? Try our streaming subscription!


Oh that's lovely. Have you showed it to her yet?
Very nice, Jo, you really feel the personal connection here, I love "tester of dreams" and "the music of tears" lovely phrases.
and the repeated image of touching hands/fingers.


You can pay your water/sewer/trash utility bills on line at our on line payment portal here.
Gonzales is a full-service City providing water, wastewater, and solid waste services. On this Utility Services section, we will provide information on utilities in Gonzales.
Water/Sewer utility bills may be paid via our on line portal, or in person at City Hall, 147 Fourth St., Gonzales, CA 93926.
There are also three drop-off location. Drop boxes are located near Starbucks in the shopping center at 851 Fifth St, next to the post office at 346 Belden St, and outside city hall at 147 Fifth St.
In order to connect, disconnect, or change utility service the Utility Service Order form must be completed, returned to City Hall at 147 Fourth St., and all required fees paid.


As parking is an issue, this sale will be hosted on Saturday and Sunday instead of our usual days. You can probably do your Christmas and/or holiday shopping in this home. Some antiques, collectibles and an abundance of great house contents.
Please check back for updated info and photos COMPLETED ESTATE SALEHave a great Holiday Season and we look forward to seeing you in 2017.59 Ainsdale Road M1R 3Z3Warden/Lawrence via Boem A sign in book will be available at the front door of the house on SATURDAY morning. Entry to sale at AM, in order of names on sheet/book. 17th - AM - pm You & your friends are invited: complete contents of 2 bedroom home. - dining table with 4 chairs (2 sets); Sideboard; kitchen drop leaf table w/2 chairs; Sofas and armchairs (2 sets); nesting tables; bedroom dressers; teak headboard; single beds; Wall unit; sofa bed; floor model stereo; china, crystal, glassware; West German vases; Doulton figurine; Records; Electric Lawn mover; shop vac; fertilizer spreader; hand/garden tools; garden furniture; tent; ladder; books; work bench; linens; clothing; knick knacks; cutlery; pots/pans/bake ware and other kitchen appliances and other items. Hard to believe this updated home is almost 100 years old filled with treasures in and outside. Information will be updated as we work in the home. 20th am til pm PLEASE NOTE: We are currently working in 3 homes, so are a little behind.
SHOES MUST BE REMOVED, SO BRING SLIPPERS YOU & YOUR FRIENDS are invited to another great sale in a lovely clean home. table/6 chairs; buffet/ hutch; Matching sofa/loveseat/chair; coffee/end tables; 3 seat couch w/matching chair; end tables; 2 sets - kitchen table/4 chairs; variety of bedroom dressers/nite tables; head boards; futon; magazine racks; misc. 17th am til pm NB: a sign in book will be placed near front door for early birds to sign. Park on one side of street only and do not park in or block off neighbours driveways.
Entry to sale will be in the order of names in the book. You & your friends are invited to another great estate sale. This home belonged to the mother of a Juno award winner and Order of Canada. ; FURNITURE: Dining room suite consisting of table/6 chairs, buffet & hutch and side server; sofas and loveseat; variety of chairs including armchairs/wing back/balloon back/ begre chair etc; variety of accent chests; bedroom furniture including dresser w/mirrors, chest on chest, night tables; bedroom dressers; headboards, footboards; TV stand; storage style drum tables; patio table; Oriental screen; wood screen; coffee/end tables; arm chairs, foot stool; Nesting tables; cedar chest PLUS LOTS MOREMISCELLANEOUS: Art/pictures/prints; mirrors; metal storage cupboards; plastic storage bins; baskets/ vacuum; paper shredder; Xmas decoration; candelabras; books; carpets/rugs/runners; collector plates; small electrical appliances ie mix master/osterizer/hot tray; griddle; linens (sheets/pillowcases/blankets/duvets; doilies; placemats/napkins/pillows;) Pots/pans/bakeware; garden items; luggage; clothing, shoes/purses/hats/Scarves/belts; lamps; PLUS LOTS MORE.... June 10th 10 am til pm You and your friends are invited to another great estate sale consisting of: Mostly mid century furniture, dining table/chairs; 3 pc. Please check website for FULL AND UPDATED details You & your friends are invited.
Available for sale will be: upright piano and piano stool; antique bedroom dresser, ornate head/foot board w/matching night table; number of small occasional tables; number of antique chairs; antique tables; antique dresser; vintage floor model stereo; antique love seat; lots of collectible china, crystal, glassware; silver and plate; records/ books; vintage toys & games; lamps including Chinese soapstone lamp; old metal trunk; pictures/prints; 1950's metal pram (great for doll display); some vintage clothing and linens; costume jewellery; Please check website regularly for further details, info and photos. PLEASE NOTE: A sign-in sheet will be provided at the front door of the house on Friday morning. Lots of collectible china some dating back to early 1900's. The Great Estate COMPLETED ESTATE SALE ETOBICOKE/MISSISSAUGA BORDERFriday, January 22nd, am - pm Saturday, January 23rd am - pm 3724 Wyewood Rd, Mississauga, ON L4T 2A2427/Rexdale (across from Woodbine Racetrack)via Humberwood/Morningstar/Corliss N. A sign in sheet will be provided at the front door of the house on Friday morning, January 22nd. Entry at am Interesting sale: Dining room table, 6 high back/cloth covered chairs, buffet/hutch; pub style kitchen table w/8 high back chairs; 3 seat sofa; recliner chair; computer desk; various bookshelves/shelving; double bed (with 6 month old pillow top mattress; Dresser w/mirror; Highboy dresser; Night table; Ikea style wardrobes; computer desks; sofas; recliner chair; bookshelves; captains bed w/ mattress; coffee/end tables; kitchen table & chairs; china, crystal, glassware; lamps; art; clothing, shoes, purses, hats; luggage; linens; LOTS of books (many books/magazines/pamphlets on high end cars ie Porsche/Ferrari/Morgan etc) ; old radio; Lots of good electronics (Panasonic/Toshiba/Yamaha/Harmon Kardon speakers/Bang Olufsen speakers; Sony Reel to Reel; luggage; Franklin Mint Flags of Canada in wood/glass case; large soapstone (signed), Professional Espresso maker w/milk steamer; bike; upright jewellery case, Lots of small hand tools, plumbing supplies; BBQ; snowblower, 2 lawn mowers; step ladders; Garage is packed full PLEASE NOTE: MORE PHOTOS WILL BE ON WEBSITE THURSDAY EVENING, SO PLEASE CHECK BACKCOMPLETED ESTATE SALEFri. Bedding and linens (sheets/pillowcases/blankets/comforters); Ping pong tables; books, old typewriter; small hand tools/garden tools/ladders; 1950s globe; table & interesting floor lamps; old ice box; skis; collectibles; artwork and pictures; glass heads; leather faces; blow fish and lizard skeleton; gold clubs; old sled; kitchen bake ware, casseroles, heating trays, small electrical appliances; PLUS LOTS MORE.... MORE INFO COMING SOONCOMPLETED ESTATE/HOUSE CONTENTS SALE57 Amberdale Drive Mc Cowan/Ellesmere via Brimorton Fri. There will be a sign in sheet posted at the front door as well. You and your friends are invited to another great sale. We are a little behind schedule for this sale, so not all items have photos or have been notated.
COMPLETED SALEPacked Oakville Estate488 FALGARWOOD DRIVE, OAKVILLEQEW//Trafalgar via Iroquois Shore Rd., & Eighth Line Fri. Please sign your name upon arrival, one name per line. AND, AS ALWAYS, please be respectful of the neighbours, DO NOT BLOCK OFF OR PARK IN THE NEIGHBORS DRIVEWAYS. (Wedgwood Ashford, Noritake Barrymore, Copeland Spode Tower Blue, Nippon, Limoge, cups& saucers,) Hughes cornflower, silver plate, Eastlake furniture items, stunning dining room table, kitchen table & chairs; piano; artwork/pictures; bedroom furniture; clothing; linens; some vintage clothing; lots of vintage toys/games; Christmas items (some vintage) hand and power tools, TOOL MAKERS MEASURING EQUIPMENT, electronics; antiques/collectible; costume jewellery; older books, magazines; records; posters; sterling silver flatware; Grandfather clock; Gingerbread clock; mid 1800"s Muscat, (smooth bore cap lock with the ram rod, proof marked and most likely European.), old tools, filing cabinet; wheelchair; children's bikes; kitchen pots, pans, bake ware, small electrical appliances PLUS LOTS MOREPS WE HAVE JUST BEEN INFORMED THAT THE STARTING TIME FOR THE SALE ARE INCORRECT. COMPLETED KINGSWAY ESTATE SALE March 18 & 19, 2016 TIME: Noon Friday - 6pm - Saturday411 The Kingsway East of Islington No parking on The Kingsway. Tickets handed out am Friday No tickets required for Saturday PLease be respectful - do not block Neighbors driveways This is the family home of a well known Canadian Entertainer and Juno award nominee. Available for sale: Vintage bedroom suite; round glass, kitchen table w/4 chairs; buffet/hutch; floor model stereo; variety of coffee/end/occasional tables; number of misc. Family are still been going through the home as we work on it......... 21, 2013 am pm You and your friends are invited: complete home contents for sale: 1900s dining room table/6chairs/sideboard/china cabinet; 100 years old); 2 Berger style chairs; variety of bedroom dressers; coffee/end/occasional tables (some antique); modern corner computer desk; Jenome sewing machine; Old singer sewing machine with stand; freezer; 1950s fridge (working); Some china/crystal, misc.
Ci sei stata a dirmi "Mi Dispiace Fla❤" per tutti i momenti brutti che ho passato e tu lo sai meglio delle altre... Io, che odio i 1D mi hai fatto cambiare e diventarne un ""fan"" per una tipa. Eppure l'ho capito da li ogni volta che mi dicevi fla prova cosi scriviji cosi e lo facevo funzionava sempre.
Numai 10% din cei care cumpără locuinţe sunt dispuşi să le ia pe cele care trec de 450.000 de lei pentru că au TVA de 19%.


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Cybersecurity & IAM
End User Management
Social & Government
New CRM system based on Dynamics 365 is the first step towards digitization for ROC Nijmegen
Yvonne Slenders, Functional Manager Yvonne Slenders
www.roc-nijmegen.nl
Industry: Education
In 2018 ROC Nijmegen said goodbye to its old CRM. After more than ten years of loyal service, the old CRM system was on its last legs. In their search for a new solution, ROC asked its trusted IT partner Cegeka for help. Cegeka's flexible project approach and the focus on simplicity and development in close consultation with ROC were the deciding factors. And soon after completion, the new CRM based on Microsoft Dynamics 365 for Sales proved to be much more than just an update for the current system.
ROC Nijmegen sends out a lot of quotes every week. They are mainly for companies looking for training courses for their employees, or for students who want to enrol in a civic integration programme. Apart from keeping track of customer data, the main task of the old CRM system was to create quotes. 'The problem was that no one was familiar with the system design,' says functional manager Yvonne Slenders. 'If we wanted to change something, we always had to call in an external party. Moreover, our version was still running locally on the PCs of our employees, which was not exactly a sustainable solution.'
A rough idea, gradually refined
The main assignment was to find a more flexible and sustainable solution. 'Our IT department came up with the idea to switch to Microsoft Dynamics 365,' Yvonne continues. 'Our office environment was already running on Office 365, so Microsoft was a logical next step. But we didn't want to leave anything to chance so we received proposals from several IT providers. Cegeka eventually emerged as the best possible partner, both because of the story they were telling and the price tag they offered.'
Their first impression was very positive: 'During the first session, Cegeka's people mostly listened to our experiences. During the second session they came up with a concrete proposal based on Microsoft Dynamics 365. A few more meetings followed, and we further refined the idea. This was the ideal approach for us, since we now have a CRM system that's tailored perfectly to our business. As a functional manager, I can also use it without any issues. Now I can easily answer questions or requests from our end users myself.'
Small successes, ballast removal
In addition to a quotation tool, the new package had so much more to offer. 'The integration with the Office 365 environment is very convenient. Small features, such as conversions into Excel tables or automatic notifications in Outlook help us save a lot of time. In addition, part of our paperwork has been digitized. In the past we had to print out invoices, sign them, send them by post, etc. Now this flow is managed entirely in Dynamics.'
ROC's other departments are also becoming interested in the new system. As Yvonne explains, 'Our internship agencies, for example, could use Dynamics to manage their contacts with the internship companies. I'm going to give them a demo soon. But other colleagues have also shown interest. We're only using a fraction of the power of Microsoft right now. It has huge potential.'
"Many other teams have already shown interest in the new CRM. They have noticed the huge potential of Microsoft Dynamics."
Outdated CRM with limited functionality
High licensing costs
System was running locally on several PCs
No internal administrator
CRM based on Microsoft Dynamics 365 for Sales
Designed according to ROC's needs
© Cegeka | Terms & Conditions | Privacy policy | Cookie statement


Manchester City manager Roberto Mancini will meet with his rebel striker Carlos Tevez tomorrow, in a bid to save the Argentine's career at the club. The two haven't spoken since Tevez's representatives informed the City hierarchy that the forward wanted to leave, but Mancini is still hopeful of persuading him to stay.
Speaking ahead of City's 1-1 Europa League draw with Juventus, Mancini said: "He is our player and it's my opinion that Carlos will stay with us. But I want to speak with him. He can continue to play for us.
While Mancini is confident of talking Tevez round, it will be a massive shock to see Tevez willingly remain at the club. I use the word willingly because in reality if City don't want to sell, they are the only club in the world that could afford to allow a player of Tevez's stature to rot in the reserves.
City's financial prowess has also meant that Tevez's valuation has been greatly inflated and there are very few clubs in the world that could afford the sort of money that City are reported to be looking for, should Tevez not be persuaded to stay.
This demonstrates just how hard it will be for Tevez to manufacture a move away from City. There is often a talk about player power in football, but this transfer saga will emphasise just how powerful City have become.
As we saw with Craig Bellamy, City have the power to pick and chose where their players go. So while Tevez might be desperate for a move away from Eastlands, he might just have to be prepared to wait a very long time for it.
Sheikh Mansour's takeover at the club has changed the footballing transfer market. While it created astronomically big wages for the likes of Tevez, it also created a new level of control over players, which has brought a whole new world of problems.
The middle ground is saying Tevez stays it's called his contract!! They may sell him in the summer though, but only for the right price (which is a high one). I note he is being careful what he's saying i.e. he likes Mancini, the fans are great etc what's the reason for this as he clearly has some issues with Mancini?
I have just read a hilarious story in the Daily Mail that states that Adebayor is going to Real on loan, don't get me wrong this could happen but the rest is pure… well I'll let you decide. Tevez is also going there but for a whooping £12m of course this is because as his value will only depreciate don't ya know as he's really old at 26, yeah well with him being one of the best strikers if not the best in England at the minute they would really except £12m all day wouldn't they?
Also the Mail report that Real are after Hernandez and will pay £21m and that Fergie will let him leave (not a prayer)and of course he's gotta be worth double what Tevez is hasn't he?????? So if he's right and these all come off they add up to around another £26m a year in wages alone but at least they saved £30m+ on Tevez eh? Well done Alex Kay (the writer) you are a complete and utter wing nut and yet another reason not to read the Daily Mail!!


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Pay Only for What You Use─Often, IT organizations will over estimate the actual software utilization by the end-user community. For example, an IT organization may forecast an active end-user community for a particular application to grow to 10,000 employees within a year. However, customization and implementation delays may result in only 500 employees actually using the software a year later. With Shop Boss Pro, corporate buyers only pay for the active users of the system–not the forecasted user community.


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"Shivaji Park"
, Showing 2908 results
All (2908)Articles (2858)Videos (47)Photos (3)
Mumbai: Congress moves HC for nod to Rahul Gandhi's rally at Shivaji Park
TNN / Dec 14, 2021, 04:11 (IST)
Following the state government's delay in granting permission for the use of Shivaji Park on December 28 for the 137th Foundation Day of the Indian National Congress, Mumbai Regional Congress Committee president Bhai Jagtap on Monday moved the Bombay high court urging it to direct the state government to give its nod.
Mumbai: CM to decide on nod for Cong rally at Shivaji Park
Dec 11, 2021, 04:46 (IST)
Murder in Shivaji Park: Carpenter freed after 6 yrs
Ban on December 6 liquor sale in Kings Circle, Wadala, few other areas quashed by Bombay HC
Mumbai actress duped of Rs 3 lakh after ordering whiskey online
TNN / Nov 29, 2021, 04:00 (IST)
A 64-year-old actress said a fraudster siphoned Rs 3.05 lakh from her debit and credit cards. She wanted to order whiskey and found the number of a wine shop on Internet, called up and paid. When she did not get it, she sought a refund.
Raj Thackeray moves into new home 'Shivtirth' in Shivaji Park
Maharashtra Navnirman Sena (MNS) chief Raj Thackeray on Saturday moved into his new house in Dadar's Shivaji Park area. His new house is named 'Shivtirth' and is in the same neighbourhood of his previous home, Krishnakunj.
Mumbai: MNS office to be housed at Raj Thackeray's new home
Maharashtra Navnirman Sena (MNS) chief Raj Thackeray moved into his new house in Shivaji Park area, Dadar, on Saturday. His new house is named 'Shivtirth' and is located in the same neighbourhood of his previous home, Krishnakunj. The name plate was unveiled by Raj's son Amit.
Dussehra rally at Shivaji Park on cards: Sanjay Raut
TNN / Oct 07, 2021, 04:24 (IST)
With the BMC election less than six months away, the Shiv Sena is set to hold a Dussehra rally later this month at Dadar's Shivaji Park. The party is mulling how the rally can be held with a limited crowd and following Covid-19 protocols.
Mumbai: CM Uddhav Thackeray inaugurates LED illumination at Shivaji Park
Chief minister Uddhav Thackeray on Thursday inaugurated the new illumination of pathways and the statue of Chhatrapati Shivaji Maharaj at Dadar's Shivaji Park.
Mumbai: Shiv Sena to hold Dussehra rally at Shivaji Park
With the Brihanmumbai Municipal Corporation (BMC) elections less than six months away, the Shiv Sena is set to hold a physical Dussehra rally later this month at Dadar's Shivaji Park.


The Playstation classic takes on the famed look of the original PSone (PSX to some of us old school gamers), but 45% smaller in comparison. The device definitely resembles that of the original, even down to the ribbed sides. The controllers even have the proper original Playstation look to them!
Something one should take into consideration with this new retro console is the very same thing that is frustrating gamers with other systems. The CD tray is a "faux tray". In other words, it does not open...at least that is what we are speculating. We think it is a safe wager at this point in the retro gaming scene. Even if it did open, you would not be able to place a proper disc into the tray due to the reduced size in comparison to the original hardware.
Now what good is this thing if you can't use discs? Well, don't worry. Sony promises us 20 built in games. What are those twenty titles? Well, fifteen of them are a total mystery. We do knwo what five of them are going to be though! We get the classics Final Fantasy VII, Jumping Flash, Ridge Racer Type 4, Tekken 3, and Wild Arms. Wild Arms is a very good RPG with a western theme. It also had some gorgeous anime cutscenes mixed in. Was it a classic? Depends on whom you ask. The others definitely have their place, and were shining examples of the power of the PSone back in the day.
There is speculation that the internal hardware will offer the user the ability to enjoy classic PSone games with "better graphics". Even though the unit uses HDMI for a/v output, this does not mean that the titles will receive any type of graphical enhancements (smoothing, perspective correction on textures, etc.). Considering the SNES Classic from Nintendo offered very little in the way of any type of visual corrections, it would come as no surprise if Sony followed suit.
Whatever other games Sony decides to include will most likely be titles that have made their way into the "Greatest Hits" line up. Those were the games that supposedly sold exceptionally well, and would also be titles that would hold the most nostalgic grip for those purchasing this little console. Some titles I would want to see is something from the Spyro franchise, Crash Bandicoot, Resident Evil Directors Cut, Metal Gear Solid, Wipeout, Warhawk, and...well, a few more of course. Tell us your choices for addition in the comments.
Whoa, whoa, whoa. We aren't done yet. We still need to talk about what we think they did wrong!
We love the fact that Sony is going with USB controllers, so that definitely opens up some possibilities because we do NOT like the fact that the included controllers are digital only. No dual analog here. This honestly limits you to what games that will come included with the unit. Any title that required Analog in some fashion will NEVER be included. Gamers that relied upon the analog to give better control to games that offered support will have to deal with digital only. However, as we said that the input is USB, perhaps we will see the ability to use our own controllers? That would be great.
Another thing we feel that Sony is getting wrong here is the massive reduction in size to the unit eliminating the potential to include disc support. Since there is no mention of expandability to the unit, and the games that will come pre-installed may not be totally worth it to all gamers, just as one can say with any "Classic" or "Flashback" console. With the unit having USB for power, one shouldn't be surprised if the unit is hacked shortly after its release.
The unit will be available to the US market December 3, 2018 with a MSRP of $99.99. This will include the unit, HDMI cable, USB cable, and two controllers.


text:
Understanding Food Insecurity
Feed Opportunity Fund
Scholarship in Food Insecurity
Content Centre
News Releases and Speeches
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Maple Leaf Foods and the Maple Leaf Centre for Food Security Announce Four $15,000 Scholarships for the 2023-24 Academic Year
Scholarships will recognize the extraordinary contribution of several past Chairs of the Maple Leaf Foods' Board of Directors, including David Emerson, Wallace McCain, Purdy Crawford, and W. Geoffrey Beattie.
MISSISSAUGA, ON, Dec. 8, 2022 /CNW/ – (TSX: MFI) Maple Leaf Foods and the Maple Leaf Centre for Food Security ("the Centre") are pleased to announce funding for four $15,000 scholarships to be awarded in the summer of 2023. These scholarships are in recognition of the extraordinary contribution of David Emerson, Wallace McCain, Purdy Crawford, and W. Geoffrey Beattie as past Chairs of the Maple Leaf Foods' Board of Directors.
Scholarships will be awarded to candidates with strong academic records, who are pursuing research that aligns with the Centre's goal to structurally reduce food insecurity, and whose research is feasible, methodologically rigorous, and will contribute to the body of knowledge on food insecurity in Canada. Masters and PhD students who are conducting thesis research on risk factors and interventions to address food insecurity are encouraged to apply.
"These scholarship students will contribute to our understanding of food insecurity, a critical health and social issue that affects one in six households in Canada," said Michael McCain, CEO of Maple Leaf Foods. "They will also enable academic researchers to pursue a field vital to advancing social, health and equity. We're grateful to the Centre's independent directors, who will conduct a rigorous review to award these scholarships to high impact research projects."
Scholarship applications will be due on February 10th, 2023. This marks the fourth year of the Scholarship in Food Insecurity program, which has financially supported nine Masters and PhD students since 2019. To learn more about these students and their research, or to learn about the scholarship awards process, visit our Scholarships webpage: www.feedopportunity.com/apply-for-funding/scholarships/.
About the Maple Leaf Centre for Food Security
The Maple Leaf Centre for Action on Food Security, operating as the Maple Leaf Centre for Food Security ("the Centre"), is a registered charity committed to working collaboratively to reduce food insecurity in Canada by 50% by 2030. The Centre advocates for critical public policies and invests in knowledge building and programs that advance the capacity of people and communities to achieve sustainable food security. The Centre was created in 2016 and is governed by a board of directors, including four independent experts.
About Maple Leaf Foods
Maple Leaf Foods is a carbon neutral company with a vision to be the most sustainable protein company on earth, responsibly producing food products under leading brands including Maple Leaf®, Maple Leaf Prime®, Maple Leaf Natural Selections®, Schneiders®, Schneiders® Country Naturals®, Mina®, Greenfield Natural Meat Co.®, Lightlife® and Field Roast™. The Company employs approximately 14,000 people and does business primarily in Canada, the U.S. and Asia. The Company is headquartered in Mississauga, Ontario and its shares trade on the Toronto Stock Exchange (MFI).
@MapleLeafFoods
@FeedOpportunity
SOURCE Maple Leaf Centre for Food Security
For further information: Media contacts: Maple Leaf Centre for Food Security:, Sarah Stern, Sarah.stern@mapleleaf.com; Maple Leaf Foods: media.hotline@mapleleaf.com
© 2023 Maple Leaf Centre for Action on Food Security. All rights reserved.


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text:
Derek Robbins (born 4 January 1952) is a Canadian former alpine skier who competed in the 1972 Winter Olympics.

References

1952 births
Living people
Canadian male alpine skiers
Olympic alpine skiers of Canada
Alpine skiers at the 1972 Winter Olympics
20th-century Canadian people

redpajama_set_name: RedPajamaWikipedia


This is both my second Humans Wanted post, AND the position the anthology has reached, so this post's title does pleasing double-duty.
EDIT: Now #1! Sad it messes up the title symmetry, but happy that it now gets the cool "#1 Best Seller" banner on Amazon. :) See below for details.
Amazon is pretty famous for awarding "Best Seller" status like candy in sub-sub-sub-niche markets where selling three copies in a day will make you a best seller. Amazon's algorithm is still pretty wonky, and anthologies are famous for not having a lot of volume. But "SF Anthologies" isn't that super-niche, the top 15 at the time this screenshot was taken includes "Machine Learning" by Hugh Howey, a Harlan Ellison collection, and "Stories of your Life" by Ted Chiang. So this is a fairly legit accomplishment!
My best guess for why this happened now – A. Merc Rustad's story "Longing for Stars Once Lost" just went live on Lightspeed a few days ago, and at the bottom of the Author Spotlight section that goes along with it, they say "Oh, and if you like my Principality Suns storyverse, I have a short story in the Humans Wanted anthology (ed. Vivian Caethe), which I hope you'll check out." I believe the spike in sales came soon after.