There are partners in crime, partners in business, and often partners in enviable romantic relationships. There are partnerships in law firms, where the list of partners begins to sound more like the contents list on a package of processed food.
Acts from the days of vaudeville had partnerships, memorable among them Burns and Allen, followed in the early days of TV entertainment with Sonny and Cher. Abbot had Costello, Martin had the bad luck of Lewis, but in mitigation, Laurel had Oliver Hardy. Thanks to the mischievous playwright, Tom Stoppard, we have a modern reprise of a great Shakespearean partnership, Rosenkrantz and Guildenstern.
Look anywhere, your memory banks included, and before long, you'll find a partnership that resonates for you with some kind of splash on the emotional scale, Nixon and Agnew, for instance, representing the equivalent of a long, sour grimace. Come to think of it, a number of U.S. Presidential combinations provoke similar tummy rumblings.
Fred Astaire, ne Austerlitz, had three remarkable dance partnerships, his sister, Adele, then Ginger Rogers and Rita Hayworth before ending his career with the lithe and stunning Barrie Chase.
Procter had Gamble. For a while, Sears had Roebuck, Chase had Sanborn, and if you spent any time in New York City, you'd recall that Horn had Hardart for the automat. If you grew up in Los Angeles, you knew that some fortunate Pig was partnered with a Whistle.
There were and, to be sure, are loners, spiky, crinkly men and women who set great store by their ability to go things alone, to give, sometimes even graciously, but, as biblical language would have it, receiveth not. These individuals often made a mini-religion of self-sufficiency to the point of sounding like those in many formal religions who begin renouncing so-called worldly things. These individuals seemed to ignore the potentials for partnership rather than espouse any overt and cranky eschewal.
Much as you like to consider yourself a traveler along the path of sufficiency, you have to report a lengthy stream of partners of one sort or another. The first was with a lad named Pierre in Miami Beach, Florida, where your business model involved repairing radios, for which you both had some limited abilities, repairing vacuum cleaners, for which you had only Pierre's word that he knew the insides of a Hoover the way you knew the back of your hand. Your goal was to be able to rent a small vacant space next to a tailor, but the available financial resources seemed always to be spent of Peter Paul Mounds bars.
The first partner in the sense of which you speak here was a tiger-striped cat named Sam, who was voted partnership after having moved his things from your next door neighbor, Ray, when you lived in the Hollywood Hills. The attraction between you was immediate. Even though you both had active social lives, you reckon the draw was a subtext sense of loneliness, which might explain why Sam, who had no use for many of the activities you associate with cats--scratch pads, indoor gyms, catnip toys--enjoyed time hunkered down on your chest while you read, slouching in a large, overstuffed club chair given you by your father. For your part, you discovered the greater joys of reading in that chair with Sam on your chest than your ordinary reading venues of bed, at your work desk, or Coffee Dan's restaurant on Sunset Boulevard.
The partnership seemed to come after a longish discussion in which you both appeared to acknowledge the need the other fulfilled. The bargain was sealed by an exchange of tokens, a carton of Kitty Queen kidney as a gift from you and what Sam believed to be a dead lizard.
In subsequent years of your partnership, cat fanciers assured you no normal cat would do, or perhaps the words were "put up with" the expectations you had of Sam, simply because they seemed appropriate. For instance, coming with you in your car when you ran errands, taking walks around the neighborhood at night, traveling to Virginia City and attending cocktail parties, sharing hamburgers, browsing used book stores, and seeming to take an interest in your work by settling down nearby when you were composing.
Another partner, Edward, was a blue-tick hound, meaning in operational terms that he was often away, sniffing things or pursuing them. Although able to find his way home, he often arrived at a destination too tired from running and tracking to move, thus he had to be picked up. Sometimes his pick-up points were remote, giving you an even greater knowledge of the outer Los Angeles perimeter.
Molly became a partner after showing her interest in accompanying you on your five- and often ten-mile daily running, but you had to learn to put up with her ability to sneak out of rooms or places you'd thought you left her.
And of course, Sally, who was known during writing conferences to become outraged if marauding coyotes drew too close, and who frequently saw the need to herd stray cats into the living room.
Your partners thus had differing, outstanding traits and quirks. They came to grudging acceptance of yours, just as you were able to pretend to be outraged by Sally's breaking up of bridge parties and social gatherings at the next door Cudahy estate while giving her sotto voce praise for her sense of social justice.
When you collaborated with Wolfe, you had to balance your interest in getting subsequent drafts done in a rush before taking on the words one-at-a-time with Wolfe's frequent returns to places you'd long thought to have been settled and/or cured.
The thrust here is how and what you learned from your partners. You for instance preach the virtues of rushing to get a draft done with as little thought as possible, but Wolfe still drags you back to an inept word or, worse, a phrase, causing you to replay it again and again until you can almost hear him, asking you, That sounds better, don't you think? That gets it done and done funny, don't you think?
Sometimes, when you are having a dialogue or, more to the point, a monologue with yourself, you're drawn back to discussions in which you explained things to Sam, then became captivated by his behavior that seemed to suggest he understood your intent.
When the Dean elevated Sally to Department mascot, then found and posted a picture of her on the department website, you wasted no time enlarging the scope and length of your conversations with her to include a complete transparency of disclosure.
How fanciful is it to have lengthy times of conversation with an animal? Who better than a partner to discuss strengths, weaknesses, strategies, and, most entrancing, the sharing of secrets ? Sophistry, right? Extended anthropomorphizing of animals, no? Except that such conversations opened the door to discussions with humans and with the self who notes things down on paper or types them for inclusion here.
This kind of partner is the partner who knows you, your oratory self and your curmudgeonly self as well as your secret self, the self you are comfortable revealing only to a partner. You are so used to your partner that you take for granted the soaring enthusiasms and comfortable stature you have achieved merely from taking things through and hanging out with someone who not only gets you but who has seen you, unshaven, unedited, unguarded.
After a time, it is difficult if not downright impossible to tell the partner anything but the truth. Is it any wonder you get the notion of having come as far as you have because of your partners? Now, you've reached the point of saving the bacon from your breakfasts, splitting tuna melts, offering strands of spaghetti bolognese, checking your partner's preferences, finding picnic sites where your partner can get some interesting scents, and discovering through studied experimentation your partner's absolute favorite, the brisket sandwich at Art's Deli on Ventura Boulevard in Studio City.
How many things of taste and preference are, in fact, influenced by your partner's taste?
These vagrant lines would not be approaching a true essay if you were not to pose the added rhetorical question, If you'd extend the same concerns and attentions to human partner potentials as you have with animal partners, wouldn't you have more close human friends?
You've thought that, in your sixteen years with Sally, you've more than once brought it up in her presence. The answer you take back from her is typical, you believe, of her judgment: If you give what you get from animals to yourself, you're better able to give proper substance to humans. If you give what you get from your animal partners to your work as a writer, an editor, and a teacher, you may find yourself chasing the occasional ball or car, but in the long run, your sentences and paragraphs will stand on their own, some dogs, some cats, and some people will trust you, and the occasional dog or cat or human will love you.
Sally certainly was the devoted companion. I don't know how she put up, so calmly, with the Luna-tics writers group. I'm sorry for your loss.
My beloved son with paws, Shadrach, passed in 2008. Even though I have 2 daughters with paw now who I adore, I still talk to Shad often. Keep talking Sally. She is close-by always.


text:
Stats from Day 2 of the 2015 World Series of Poker Main Event Final Table
November 10 2015 Donnie Peters
On Sunday, the 2015 November Nine returned to battle down to the final six in the World Series of Poker Main Event. The first day saw 72 hands play out, three eliminations take place, and plenty of chips added to Joe McKeehen's stack. Monday saw the final six return with the goal of cutting three more from the mix. When it was all said and done, 71 hands later, McKeehen again stood atop the mountain. He was joined by Neil Blumenfield and Josh Beckley.
After reviewing the hands from the first day of play, it was revealed that the most active and aggressive players rose to the top. Much of the same occurred on Monday, with the numbers showing us that it pays to attack in poker rather than sit back and wait. McKeehen did just that, and his continued command over the rest of the field is as visible as its ever been. For the two that will join him on Tuesday, they also exhibited activity and aggression on Monday that helped them advance.
With the help of the live updates posted on WSOP.com, let's take a look at the stats from the second day.
Hands Dealt
VPIP
PF 3-Bet
J. McKeehen 71 33 23 2 1 -- 2
N. Blumenfield 71 17 9 4 1 -- 2
J. Beckley 71 24 14 5 -- -- 1
M. Steinberg 71 16 10 5 -- -- 2
O. Stern 49 16 10 -- -- -- --
T. Cannuli 2 1 1 0 -- -- --
Once again, McKeehen was by far the most active player, voluntarily putting money into the pot on 33 occasions, or over 46 percent of the time on Monday. This was more than he played on Sunday, where he voluntarily putting money into the pot on 28 of 72 occasions for nearly 39 percent activity. The increase wasn't unexpected, though, so don't be surprised. The change lines up thanks to the combination of short-handed poker and McKeehen's increased dominance of the table.
Although McKeehen played a highly-active style with lots of aggression, his first three-bet didn't come until Hand #104, or the 32nd hand of Monday.
Most people were pleasantly surprised to see how much Blumenfield opened up his game on Sunday, as many expected a snug form of poker from the 61-year-old player. Instead, he came out firing from the start, three-betting on Hands #3-5 and raising on the Hand #6. On Monday, it appeared he was going with the same game plan. The first two hands that Blumenfield played on Monday were both with him three-betting. He was also the first player to stick in a four-bet on the second day of action.
Max Steinberg also came in starting the same way he did the day before. On Sunday, Steinberg was the first to get aggressive and raised on the first hand. On Sunday, he did the same thing and raised on the first hand.
Knowing how active Blumenfield played on Sunday and his quick continuation of this style on Monday, it's a bit surprising his opponents didn't take more opportunities to play back at him. In particular, there was one hand shown on the ESPN broadcast where Steinberg raised on the button with and Blumenfield three-bet from the big blind with . Steinberg opted to fold.
Another similarity to Sunday was that an elimination occurred on the second hand of the day, with Thomas Cannuli's aces getting cracked by Steinberg to bust in sixth place.
Including all-in pots, there were nine showdowns on Monday, down one from Sunday's 10. Two of those resulted in chopped pots, and, including all-in pots, only Ofer Zvi Stern and Cannuli failed to win at showdown. McKeehen, Blumenfield, and Steinberg won two showdowns, and Backley won one.
Of the 71 hands dealt on Monday, four of those were all-in preflop showdowns and 45 of the other 67 were hands that didn't make it to a flop. Of those 45 hands that didn't see a flop, 30 were won with a single preflop raise.
Now, combining the numbers from Sunday and Monday, let's see what we've got.
J. McKeehen 143 61 40 5 2 -- 5
N. Blumenfield 143 40 19 10 2 1 3
J. Beckley 143 35 21 8 -- -- 1
M. Steinberg 143 27 17 6 -- -- 1
O. Stern 121 39 23 5 -- -- --
T. Cannuli 74 11 8 1 -- -- --
P. Neuville 72 9 4 1 1 -- --
F. Butteroni 35 2 1 1 -- -- --
P. Chan 2 1 -- -- -- -- --
As you can see from the overall numbers, McKeehen, Blumenfield, and Beckley have been the most active and aggressive players, and now those three comprise the final three in the event. This is not by coincidence. Aggressive and staying active pay in poker, and right now it's paying these three players at least $3.4 million.
After Sunday, McKeehen had the biggest increase in his stack, upping it by almost 45 percent from 63.1 million to 91.35 million. The next biggest positive move was Blumenfield, who increased by over 43 percent. Let's see how everyone did on Monday.
Chips at Start of FT
Chips at End of Day 1
J. McKeehen 91,350,000 128,825,000 +41.02%
N. Blumenfield 31,500,000 40,125,000 +27.38%
J. Beckley 10,875,000 23,700,000 +117.93%
M. Steinberg 16,000,000 0 -100%
O. Stern 32,500,000 0 -100%
T. Cannuli 10,425,000 0 -100%
Once again, McKeehen saw an increase of more than 40 percent to his stack. Blumenfield also saw a solid jump of over 27 percent, but it was Beckley who added the most compared to what he started with and added nearly 118 percent. The only problem here is that Beckley started pretty short, so his end result still has him last in chips heading into Tuesday's final day.
It's also worth noting that heading into the second day, McKeehen had 2.81 times Stern's second-place stack. Heading into the third day, McKeehen increased that. His stack of 128.825 million is 3.21 times that of Blumenfield's 40.125.
The collapse of Stern was the most telling here, as he was from 32.5 million to start the day to out in fifth place. Stern took a severe hit when he shoved blind versus blind against Beckley with the . Beckley woke up with two aces in the big blind and doubled up. Stern could never find his footing after that.
Knowing how aggressive and active Blumenfield has played so far, it's going to be interesting to see if he continues the same at the start of Tuesday's final three or sits back a little bit hoping that McKeehen will dismantle Beckley. He's surprised us so far with his willingness to up the aggression at the table, but that lends itself to another interesting question. Could we see a Joseph Cheong-like blow up from Blumenfield against McKeehen? He has the direct position on McKeehen, and Blumenfield certainly hasn't shown that he likes to back down. If a spot comes up where McKeehen has a big hand, but Blumenfield thinks he is just pushing him around, things could get really fascinating. It could end up gifting Beckley a spot in heads-up play, but we'll have to wait until 6 p.m PT today to find out.
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PokerNews Staff Predictions for the 2015 World Series of Poker November Nine
Joe McKeehen, Neil Blumenfield & Josh Beckley Comprise Final 3 of 2015 WSOP Main Event

redpajama_set_name: RedPajamaCommonCrawl


text:
In ambito economico, lequilibrio è una condizione del sistema economico in cui le forze sono equilibrate: in assenza di fattori esterni, le variabili micro e macroeconomiche rimangono immutate.

Descrizione
L'equilibrio è la condizione in cui il prezzo di mercato è determinato in un regime di concorrenza perfetta: tale prezzo è strettamente legato alla domanda e offerta. Adam Smith, economista affiliato alla teoria liberista, ribattezzò questo fenomeno dinamico "mano invisibile".

Soluzione di un problema di 'prezzo di equilibrio'
Per risolvere il problema di prezzo di equilibrio si devono tracciare le curve d'offerta e di domanda ed eguagliarle in equazione.

Un esempio può essere:

In qualsiasi prezzo al di sopra P offerta supera la domanda, mentre ad un prezzo inferiore P, la quantità eccede l'offerta. In altre parole, se i prezzi di domanda e offerta non sono uguali, allora sono definiti punti di squilibrio, e creano eccesso o carenza di bene.  Cambiamenti nelle condizioni di domanda o di offerta sposteranno a loro volta le curve di offerta e di domanda finché non si troveranno in equilibrio.

Si consideri il seguente schema di domanda e offerta, dove in corrispondenza di ciascun prezzo sono riportate le unità di bene domandate dai consumatori e offerte dai produttori:

 Il prezzo di equilibrio del mercato è pari a € 5,00 dove la domanda e l'offerta sono pari a 12.000 unità

 Se il prezzo corrente di mercato è di € 3,00 - vi sarebbe un eccesso di domanda per 8.000 unità, creando una carenza di bene.

 Se il prezzo corrente di mercato fosse di € 8,00 - vi sarebbe eccesso di offerta di 12.000 unità.

Quando vi è una carenza nel mercato, al fine di correggere questo disequilibrio, il prezzo del bene sarà aumentato a un prezzo di € 5,00, riducendo così il quantitativo domandato e aumentando quello offerto, così da mantenere il mercato in equilibrio.

Quando vi è un eccesso di un bene, ad esempio quando il prezzo è al di sopra di $ 6.00, allora i produttori di diminuiranno il prezzo al fine di aumentare la domanda di richiesta per il bene, in modo da eliminare l'eccesso e tornare all'equilibrio di mercato.

Altri progetti

Collegamenti esterni

Teorie in economia

redpajama_set_name: RedPajamaWikipedia


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text:
Q: Reading Binary file till the end c++ So i have this binary file with some player's data written in it.
I want to print the hole file, ( i have class player that contains some data)
there is some data printed to the screen but after that an exception is thrown.
void Player::print_statistics()
{
    ifstream file; string str; Player plyr;
    file.open("player_database.dat", ios::binary);
    while(file.read((char*)&plyr, sizeof(Player)))
    {
        file.read((char*)&plyr, sizeof(Player));
        cout << plyr.full_name << "   " << plyr.ingame_name << "   " << plyr.age << "   " << plyr.hours_played << "\n";

    }
}

Exception thrown: read access violation. _Pnext was 0x148E2B4. occurred.
  I tried the following:
while(!file.eof())

doesn't work
while(file>> string)

doesn't work.
This is the calss :
using namespace std;
class Player
{
protected:
    string password;
    int age = 0;
    long int id_nmber=0 ;
    string email, ingame_name, full_name;
public:
// ...
};

redpajama_set_name: RedPajamaStackExchange


The latest pursuit of perfection from the unpronounceable Swedish hypercar company, the Koenigsegg Agera R debuted at the Geneva Motor Show in 2011. A special edition of the Agera, it is more powerful than its big brother and runs on the same green diet as its 2007-launched predecessor, the CCXR.... Koenigsegg's newest car is the Agera R, revealed at the recent Geneva motor show. Agera means to take action in Swedish but that seems an inadequate moniker for something this extreme. Agera means to take action in Swedish but that seems an inadequate moniker for something this extreme.
The Agera R is the only roadster Hypercar with a detachable and stowable hardtop, bringing the best of two worlds. This in combination with 120 litres of luggage space, truly combine extreme performance with everyday usability.... Unfortunately you can not buy this megacar, but the magnificent Koenigsegg Agera R is available for purchase, and you can check it out in our shop. The One:1 actually is extreme model based upon the Agera model series.
But the good news is that it's one of the most powerful Koenigsegg Agera RSs ever built. It is called the Koenigsegg Agera RS1, and it has premiered at the New York Auto Show. That's on now.
The driver and co-driver of a special Koenigsegg Agera R have been hospitalised after a serious crash at the Nurburgring. The prototype vehicle, believed to be a limited edition of the Agera R, slammed into the Armco barriers, resulting in heavy vehicle damage.
The Koenigsegg Agera R is a hypercar produced by Koenigsegg from 2013 to 2015 that is a variant of the Koenigsegg Agera hypercar produced from 2011 to 2017.
To act or not to act, that is the question. The Koenigsegg Agera is the successor to the Koenigsegg CCX. This mid-engined hypercar is powered by an in-house developed 5.0-litre twin-turbocharged V8 engine, which produces 940 hp and 810 lb-ft of torque.


I caught up with filmmaker K Rajagopal over a quick coffee in the week before the 4th Singapore Short Films Awards present him with an Honorary Award for his contribution to the local film stable and the depth of local stories in our collective memories. I first knew Raja when I became his line producer for The Lucky Seven Project in 2007. He spared no time in giving me an introduction to his films and what he seeks in his films. They are very personal journeys. Many publications have written about Rajagopal and his films. However, I feel it is almost hard to academically discuss his films. I would rather read the man than read his designs. Here is my 10 minutes with Raja and a rare glimpse of a younger him.
Photograph by Wah. A younger Rajagopal poses for this photo in New York in 1992.
Jeremy (J): A common thread I noticed in your films is characters longing for gratification to fill some void in their lives. Some people say filmmakers make films that mirror their own lives. Is this true? What's that void in your life?
Rajagopal (R): I am full of memories. Both good and bad. Sometimes i feel it is an overload and I should just drop the baggage and shake it all off. Perhaps it is true that what i feel or experience in real life is some what reflected through the characters or images in my films. Perhaps there is a void which I am still trying to fill. I am still searching. Not sure what it is.
J: I know u are embarking on your feature film this year. In some way, it's your first feature, how is it different from the previous short films you have made? Anything you would be trying that u have not tried before?
R: It is going to be different because firstly I would need a lot more time and it is a different genre. The story telling in short films is definitely different from a feature length film. It will not be completely experimental like some of my short films. It is a simple narrative.
J: Name me 3 persons (anyone from singapore to Hollywood) you would like to cast in your films and what would u make them do in your films?
R: Haha ! There are many actors I would like to work with like Javier Bardem ! but I am quite realistic so I will cast an actor who will suite the role and he will be from Singapore. Also, I find average people on the streets very interesting and often like to work with non-actors.
J: Many people have done retrospectives, feature interviews, veteran-worshipping features of you. Take away the worshipping, what would u prefer to be known for?
R: I would like to be honest as far as possible when I make my films. I strive towards that. I am not sure.
Read more about K Rajagopal and a summary of his works in the 4th Singapore Short Films Awards website.


Many well-known models in the natural sciences and engineering, and today even in economics, depend on partial di?erential equations. Thus the e?cient numerical solution of such equations plays an ever-increasing role in state– the-art technology. This demand and the computational power available from current computer hardware have together stimulated the rapid development of numerical methods for partial di?erential equations—a development that encompasses convergence analyses and implementational aspects of software packages. In 1988 we started work on the ?rst German edition of our book, which appeared in 1992. Our aim was to give students a textbook that contained the basic concepts and ideas behind most numerical methods for partial di?er- tial equations. The success of this ?rst edition and the second edition in 1994 encouraged us, ten years later, to write an almost completely new version, taking into account comments from colleagues and students and drawing on the enormous progress made in the numerical analysis of partial di?erential equations in recent times. The present English version slightly improves the third German edition of 2005: we have corrected some minor errors and added additional material and references.


text:
Based: Kannapolis, United States
First Grand Prix: 2016
Team Principal: Guenther Steiner
World Championships: N/A
2021 Drivers: Mick Schumacher and Nikita Mazepin
Website: www.haasf1team.com
The youngest team on the grid, Haas made their highly impressive debut in 2016, and in the process became the first all-American-led F1 squad in three decades. Founded by industrialist Gene Haas, they are based in the United States on the same Kannapolis, North Carolina facility as his championship-winning NASCAR Sprint Cup Series team, Stewart-Haas Racing. The Ferrari-powered team, led by the charismatic Guenther Steiner, also have a UK factory in Banbury. (Bio from Formula1.com).


text:
Nicholas Kristof
columnist, NY Times, 1990 & 2006 Pulitzer Prize
Nicholas D. Kristof, a columnist for The New York Times, won a 2006 Pulitzer Prize for his writing on Darfur, which got the world's attention focused on this heartrending situation. He writes op-ed columns that appear each Wednesday and Saturday. Previously, he was associate managing editor of The Times. Kristof graduated Phi Beta Kappa from Harvard in three years, and then won first class honors in his study of law at Oxford University on a Rhodes Scholarship. Kristof joined The New York Times in 1984. After that, he served as a business correspondent based in Los Angeles, and was Bureau Chief in Hong Kong, Beijing and Tokyo. In 2000, he covered the presidential campaign and in particular Governor Bush, and he is the author of the chapter on Mr. Bush in the reference book The Presidents. In 1990 Kristof and his wife, Sheryl WuDunn, also a Times journalist, won a Pulitzer Prize for their coverage of China's Tiananmen Square democracy movement. They were the first married couple to win a Pulitzer for journalism. Kristof has won other prizes including the George Polk Award and the Overseas Press Club awards.
www.ctforum.org
11.26.2007 (1:17:38)
Why Africa Matters


Kilbride, PJ; (2016) Experimental and mathematical modelling of the culture and cryopreservation of a bioartificial liver device utilizing a 3D cell scaffold construction. Doctoral thesis , UCL (University College London).
Acute Liver Failure has poor prognosis; current treatment - liver transplant - cannot keep up with demand. Due to its regenerative capabilities, a damaged liver could heal if its functions were temporarily carried out by a separate device. A bioartificial liver device (BAL) could provide functional support while the organ heals, eliminating transplant and lifelong immunosuppression requirements. This device consists of a 2 litre biomass of alginate encapsulated HepG2 liver cells. The aim of this PhD is to cryopreserve this biomass in a single cassette and recover viable cell number within 72 h of thaw by researching the physical and biological implications of scaling-up cryopreservation from 2ml to 2 litres. Heat transfer, ice formation patterns, ice nucleation, and thawing profiles were examined and used to optimise cryopreservation protocols. Ice structure was substantially different after scale-up, with network solidification present in 2ml but progressive solidification in 2 litre volumes – this reduced post-thaw viable cell number 24 h post-thaw, but faster recovery eliminated differences by 48 h. There was a strong spatial element after scale-up - biologic freezing later demonstrated reduced post-thaw function. This was solved by inclusion of supernatant medium acting as a solute and heat sink. The warming rate of the 2.3 litre mass was reduced to <1°C/min – the critical step during thawing was the final melting step – this should be rapid. The effect of cold on hepatocyte proliferation was studied and a new method, termed here cryoanaptiksi, developed that uses chilling to induce rapid cell proliferation. Oxygenation and fluidisation of the bioreactor was modelled to determine more effective cell culture methods. Using optimised protocols, successful cryopreservation of the BAL has been demonstrated – a 4 times greater volume than any cryopreserved mammalian biomass recorded in the literature. This work gives strong foundation towards successful clinical delivery of a BAL.


text:
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Rosin, Shmuel
(1890–1941), Yiddish poet and short-story writer. Born in Shumiachi, Belorussia, into the family of a village trader and coachman, Shmuel Rosin received a traditional Talmudic education, but around 1905 was influenced by socialist ideas and became involved in the Bundist movement. He settled in Ekaterinoslav (mod. Dnipropetrovs'k) and worked as a painter and tinsmith. Subsequently, in the second decade of the 1900s, he spent time in Odessa, Kharkov, Penza, and Jewish agricultural colonies in southern Russia.
Following his poetic debut in 1917 in the Minsk Bundist newspaper Veker (Alarm Clock), Rosin wrote poems for periodicals. His first two poetic collections appeared in 1919: Moyerkeplekh (Seashells), published in Kharkov, and his children's book Bobe-mayses (Fairy Tales), published in Ekaterinoslav. His play Di oyfvakhung (The Awakening) was staged by a Kharkov theater in 1919. Rosin also contributed to the Komsomol-sponsored collection Yugnt (Youth; 1922), produced by Arn Kushnirov, who had been his roommate in Kharkov in 1919 and 1920.
Rosin's most active period began in 1921 when he moved to Moscow. That September, he was elected to the managing committee of the Moscow Circle of Yiddish Writers and Artists. He wrote prose and poetry on various topics. In 1926, the Kharkov literary journal Di royte velt (The Red World) published his story "Gesheens" (Events), whose heroes participate in the revolution. Shortly thereafter, that journal featured some of Rosin's apolitical poems, including one about a stag with golden antlers. Still, it was the revolution and civil war that dominated his writings, as reflected in the poem "Shayn" (Light; 1921)—which he would later regard as his first mature work—and other poems and stories written in the 1920s.
Soviet critics generally hailed Rosin's literary output, though they noted that his heroes had difficulty balancing their personal quests with the needs of the revolution. According to Yekhezkl Dobrushin, who in 1925 edited the Moscow almanac Nayerd (New Land), to which Rosin contributed, Rosin's poetic collection Tsu ale, tsu undz (To Everyone, to Us; 1929) marked the writer's complete transformation into a proletarian literary figure.
In addition to publishing a dozen of his own volumes, Rosin contributed to numerous collections. In 1932, he settled accounts with his Bundist past by taking part in the anti-Bundist almanac Der veg fun farat (The Road to Treason), edited by Kushnirov and Yoysef Rabin. For the almanac Sovetish (Soviet), published in 1934 on the eve of the First Congress of Soviet Writers, Rosin poeticized the story of the non-Jewish revolutionary Mishka, who was born out of wedlock after his mother was impregnated by her employer, a landowner. Indeed, illegitimate children were typically regarded as a good reservoir of revolutionaries. That same year, Rosin's poem "Zin un tekhter" (Sons and Daughters) also appeared in unabridged form.
Rosin collaborated with Shmuel Halkin on a Yiddish translation of the Armenian epic David of Sasun in 1940. In his final long poem, Trayhayt (Loyalty), published the following year, he portrayed a young Jewish worker who matures as a soldier of the revolution. Rosin volunteered for the Red Army in July 1941 and was killed in action that October.
Aron Kushnirov, "Shmuel Rosin," Heymland 2 (1947): 144–149; Boris Mogilner, ed., Di lire (Moscow, 1985).
Gennady Estraikh


History comes alive when you visit Mrauk U, earlier known as Myohaung. This is one of the most famous places in Myanmar appreciated for its archaeological marvels of ancient medieval times, situated 11km eastward of Kaladan River in the northern Rakhine state. Founded in 1433, it served as Rakhine's capital and was the business hub for international trades, till 18th century.
The city is populated with temples, pagodas and buildings which are centuries old, the eminent ones being Shite Thaung temple, Koe Thaung temple, Htukkanthein temple and five ManAung pagodas, and hence the name Myohaung, meaning the "old city". The entire village thrives on these temples and the visiting tourists. Earlier, the temples were mistaken as forts due to their bunker style wall architecture built to withstand the strong Rakhine winds.
As a foreign tourist you need to pay US$5 as an entry fee to stay in Mrauk U which you can pay at the official counter at Shittaung pagoda. To get in, you can easily take a flight to Sittwe, one hour from Yangon and then connect to Mrauk U on private boats which will take around 5 hours and charge you $10-$20 depending on the whether it's a normal speed or express one. You can also rent a private boat from Sittwe that will save you travel time and also a night in Sittwe as you won't have to rely on government ferry timings but will cost you US$50-80 depending on your bargaining skills and the headcount in your group. There are buses too but recent developments don't permit independent foreign nationals to travel by road.
With its archaeological significance, Mrauk U houses an Archaeological museum inside the Royal Palace which exhibits a collection of antique artifacts. Few options to go around in Mrauk U are bicycles, trishaws or hire a horse cart to try day trips in Chin villages, habitat of the Chin tribe and also visit Wethali which was the capital of Arakan kingdom 1500 years ago. Mahamuni Paya and Great Image of Tsu Taung Pre are notable sites to visit. Do not forget to try the authentic Rakhine cuisine.


text:
package ch.ethz.karto.map3d.gui;

import ika.utils.Sys;
import ika.utils.TextWindow;
import java.io.PrintWriter;
import java.io.StringWriter;
import javax.swing.JOptionPane;

/**
 * Error messages to inform the user about missing OpenGL or insufficient version.
 * @author Bernhard Jenny, Institute of Cartography, ETH Zurich
 */
public class Map3DOpenGLErrorMessage {

    /**
     * Displays a dialog informing about the absence of OpenGL2. Suggests simple
     * system dependent measures to solve the problem.
     * @param appName The name of the application.
     * @param exit If true, the user is informed that the application will exit.
     */
    public static void noOpenGLMessage(String appName, boolean willExit) {

        final String newLine = System.getProperty("line.separator");
        final String errorTitle = appName == null ? "Error" : appName + " Error";

        StringBuilder sb = new StringBuilder();
        sb.append("OpenGL and JOGL are not accessible.");

        // DLLs must be in the same folder as the exe file.
        if (Sys.isWindows()) {
            sb.append(newLine);
            sb.append("Please make sure the four DLL files are in "
                    + "the same folder as ");
            if (appName == null) {
                sb.append("the exe file.");
            } else {
                sb.append(appName);
                sb.append(".exe.");
            }
        }

        // updating the driver for the graphics card should solve the problem.
        if (!Sys.isMacOSX()) {
            sb.append(newLine);
            updateDriverString(sb, appName);
        }

        // possibly mixed up 32 and 64 bit versions
        if (!Sys.isMacOSX()) {
            sb.append(newLine);
            sb.append("You are possibly trying to run a 32 bit version "
                    + "with 64 bit Java, or vice versa.");
        }

        // inform about immediate shut down
        if (willExit) {
            sb.append(System.getProperty("line.separator"));
            sb.append(appName == null ? "The application" : appName);
            sb.append(" will exit now.");
        }

        // don't use ErrorDialog, which would delay the display of
        // the dialog to make sure it is in the EDT, at which time
        // System.exit is already executed.
        JOptionPane.showMessageDialog(null, sb.toString(),
                errorTitle, JOptionPane.ERROR_MESSAGE);

    }

    /**
     * Displays a dialog informing about the absence of OpenGL version 1.1.
     * This should be called if OpenGL prior to version 1.1 is present.
     * @param appName
     * @param willExit
     */
    public static void noOpenGL1_1(String appName, boolean willExit) {

        final String newLine = System.getProperty("line.separator");
        final String errorTitle = appName == null ? "Error" : appName + " Error";

        StringBuilder sb = new StringBuilder();
        sb.append("OpenGL version 1.1 or higher is required.");

        // updating the driver for the graphics card should solve the problem.
        if (!Sys.isMacOSX()) {
            sb.append(newLine);
            updateDriverString(sb, appName);
        }

        // inform about immediate shut down
        if (willExit) {
            sb.append(newLine);
            sb.append(appName == null ? "The application" : appName);
            sb.append(" will exit now.");
        }

        // don't use ErrorDialog, which would delay the display of
        // the dialog to make sure it is in the EDT, at which time
        // System.exit is already executed.
        JOptionPane.showMessageDialog(null, sb.toString(),
                errorTitle, JOptionPane.ERROR_MESSAGE);

    }

    /**
     * Inform the user about a fatal error and an immediate shut down.
     * @param ex
     * @param appName
     */
    public static void fatalErrorMessage(Throwable ex, String appName) {

        final String newLine = System.getProperty("line.separator");
        final String errorTitle = appName + " Error";

        StringBuilder sb = new StringBuilder();
        sb.append("An error occurred. ");
        sb.append(appName == null ? "The application" : appName);
        sb.append(" cannot run.
");

        if (ex != null && ex.getMessage() != null) {
            sb.append("Error: ");
            sb.append(ex.getMessage());
        }
        sb.append("");

        // don't use ika.utils.ErrorDialog that would search for
        // a parent frame, which is potentially corrupt
        JOptionPane.showMessageDialog(null, sb.toString(), errorTitle,
                JOptionPane.ERROR_MESSAGE);

        // show a stack trace if the exception has no message
        if (ex != null && ex.getMessage() == null) {
            StringWriter sw = new StringWriter();
            sw.write(errorTitle);
            sw.write(newLine);
            sw.write("Please send this report to jenny@karto.baug.ethz.ch");
            sw.write(newLine);
            PrintWriter pw = new PrintWriter(sw);
            ex.printStackTrace(pw);
            pw.flush();
            new TextWindow(null, true, true, sw.toString(), errorTitle);
        }
    }

    /**
     * Appends a message suggesting to update the driver for the graphcis card.
     * @param sb
     * @param appName
     */
    private static void updateDriverString(StringBuilder sb, String appName) {
        sb.append("Please update the driver for the graphics card and then try "
                + "running ");
        sb.append(appName == null ? "the application" : appName);
        sb.append(" again.");
    }
}

redpajama_set_name: RedPajamaGithub


No, not planning to do that, but I did just want to say the nobody is truly ready to have their first baby - whether you are 18 yrs old or 32 yrs old, it's a huge adjustment for anyone!!
Sorry you are feeling overwhelmed. Those feelings are normal and okay. If you continue with the adoption option, I hope you find the perfect family. If not, I think you are more capable as a mother than you know!
I'm just curious about your situation.
2- What is the situation with baby's father?
3- Do you have a support system? Family/friend?
4- Are you in school? Or are you working?
5-How do you plan to take care of baby afterwards.
I would also recommend talking with your dr or therapist.
I just want to let you know that you have every right to think about adoption. It is a brave and kind choice to be able to give someone a child to love. I just want you to do what is best for baby and you.
So you took a post about adoption to comment about abortion? Reading is fundamental.
Do you actually know anyone who is adopted?! Every single adopted person I know is thankful that their biological parents made the decision to find them a family that was ready to give them the life they deserve. Do you know what a huge gift this is to a childless couple longing for a baby? "close your legs" is a vile and cruel thing to say... I hope it makes you feel better about your abortion to be judgmental and cruel to mothers who find themselves in a similar situation to the one you were in.
You killed your baby, by aborting.
OP (original poster) is giving hers a chance at life, by considering adoption.
Maybe you should've been the one to "close your legs".
Adoption can be very hard. We were in the process of adoption last Spring when something changed and we ended up not getting to adopt him. It was heartbreaking for us, but he ended up in very good place with a family member of the birth mother. Adoption is a wonderful blessing to so many, open or closed. In many cases I love the idea of an open adoption. They can be really hard at first, but bring so much closure and happiness long term. I know many people who are adopted and have adopted and I think it is a very honorable thing if it is what is right for your family. Follow your heart and don't be pressured by others.
Hi! I was 17 with my first and considered adoption strongly. Because I was homeless and in foster care and not ready all. I decided to keep my baby and was able to get myself ready and it's been wonderful. Becoming a mom is hard for people of all ages and situations and just know if it IS something you have thought of wanting to do, I think you can do it!!
I also understand that may not be best for you or the baby. It is so kind and selfless for you to consider adoption for the sake of your baby. There are many people who would love to love your child. God bless and go whatever route is best for you.


"I'm trying to take a nap here," Giuseppe says.
"I'm trying to work here," I respond.
"But it's so nice and toasty warm here," he replies.
"It won't be if I turn off the lights," I tell him.
"I need my beauty rest. Mlle. Daisy may contact me at any moment and I need to look perfect," he insists.
"Mlle. Daisy can't see you," I inform him.
"But I can see her! Of course she can see me!" he seems upset. I let it go. "Mlle. Daisy loves you no matter what you do, she tells you that all the time," I say.
"But I can never be too sure, I did hear there is at least one other black cat who visits her door, I need to be very careful," Giuseppe says.
"If you like to eat, you might consider moving to a more comfortable spot to get your beauty rest than lazing all over my desk so that I might get some work done," I remark.
"But I have to he right here if Mlle. sends a message, and I have to be perfect!" he protests.
"Giuseppe, the two of you don't have Skype or anything, she can't see you when she sends you a message," I tell him again.
"No, baby, she can't see you. Can you see her when you send a message?" I ask.
"Not when I send a message, but I just always thought she could see me," Giuseppe says, confused.
"It's just words right now, Big Guy, you don't need to comb your ear hair and shine your whiskers," I tell him.
"I'm so disappointed…" he trails off.
"Can we send Mlle. a message right now?" he asks.
"Mlle. Daisy, mon cherie, I love you with all my heart and every piece of fur on my body!" he says. I type this.
"And, and…I have a gift for you! It will be a surprise," he continues.
"That's very sweet, Giuseppe. Anything else?" I ask.
"Love and kisses, nuzzles and purrs, your love, Giuseppe," he finishes.


text:
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is a Senior Staff Writer for and has covered the Stars since 1994.
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We're not going to have a lot of room for error.' We have a tough opponent coming up this week, so we have https://www.footballapparelsproshop.com/Dallas-77-Jersey do a good job of finding a way to get better this week.
He has hit .267 .470 in four years in the big leagues with 67 home runs and 227 RBI.
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They want to sit down and talk, but my thing is it?s way beyond this year.
• The CFL's Edmonton Eskimo football club said its board of directors has made the decision to discontinue the use of the word Eskimo in the team's name.
Kawhi Leonard 6.
The events can be seen on the NHL App, , Blues social media, FOX Sports Midwest and FOX Sports GO.
• The NHL concluded Phase 3 of its Return to Play on Saturday with no positive test results for COVID-19 among the 4 tests administered to more than 800 players during the period from July 18.
The Marlins postponed their flight home Sunday night after their series finale against the Phillies.
Louis resident and manager of the Soulard Market, was still beaming on Thursday, the day after the Blues defeated the Boston Bruins of the Stanley Cup Final, giving the Blues their first Stanley Cup championship since joining the NHL in 1967.
The pair have 57 caps between them.
In our quest to find quirky alternatives for a healthy diet, we come across interesting edible items – the banana tea being one of them.
Have you heard him toss out a half-hearted that's on me or I've got to be better?
One out of three Americans – about 95 million – played golf on a golf course or alternate venue, watched on TV or read about it in 2015.
1 spot among jersey sales from the NBA Store on Fifth Avenue in New York and at from November-April, according to the NBA.
We come together when it matters, and I think tonight was just a good example of that.
The New York Yankees-Phillies game scheduled for Monday night in Philadelphia has also been postponed.


One thing is certain, this is not going to end well.
Bottom line, voting members of the Fed continue to believe that running off the balance sheet is somewhat harmless and no big deal. We hear that all the time and I'll just reiterate my belief in taking the other side of that trade. No surprise at all to my readers. Whether its QT or a rate hike, it still is another form of tightening and the Fed is thus ramping up its pace of policy change in the 9th year of the expansion and in the context of a bull market that is making a run at the longest ever. We must also acknowledge that QT will be beginning just as the ECB is announcing its next taper.
For what's to come, I'm glad Jamie Dimon finally agrees with what I've been saying forever.
***ALSO JUST RELEASED: SURPRISE: This Is The Metal That Dr. Marc Faber Predicts Has The Most Upside CLICK HERE.


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Mumbai: Market went all guns blazing after the benchmark Sensex today leaped 521 points -- its biggest single-day gain in nearly five months -- to 28,051 and the Nifty crossed the 8,600-mark on a flurry of buying amid solid overseas cues.
Investors were markedly optimistic in anticipation of positive announcements on the GST front as the GST Council meeting got under way to decide on rates and slabs of the indirect tax, due to be rolled out from April 1 next year. They also stepped on the pedal to cover short positions, which led to the upmove.
Besides, there are expectations that inflation will stay in the RBI comfort zone, which will usher in lower borrowing costs. The rupee recovering against the dollar too had a positive impact.
Global indices trended up after an unexpected fall in US manufacturing index tempered hopes of an interest rate hike by the Federal Reserve, brokers said.
The 30-share BSE Sensex resumed higher and quickly crossed the 28,000-mark to hit a high of 28,064.39 before settling at 28,050.88, a significant gain of 520.91, or 1.89 percent. This was the biggest single-day gain since May 25 when it had gained 575.70 points.
The gauge had lost 143.63 points, spooked by tepid start to second quarterly earnings and a lacklustre global trend. The NSE Nifty retook the 8,600-mark to touch a high of 8,659.80 and finally settled up 157.50 points, or 1.85 percent, at 8,677.90.
In the process, both the Sensex and the Nifty recorded their biggest single-day gain in nearly five months.
Banking hogged all the limelight, with private lender ICICI Bank zooming 4.58 percent. Axis Bank rose 2.59 percent, HDFC Bank 1.58 percent while SBI gained 1.50 percent. The second-line stocks too witnessed heavy buying, lifting the mid-cap index by 1.89 per cent and small-cap by 1.30 per cent.
Among sectoral indices, the banking index topped the chart by climbing 2.37 percent followed by capital goods 2.07 percent, IT 1.84 percent, metal 1.82 percent and technology 1.68 per cent.
Out of the 30-share Sensex pack, 28 scrips ended with gains while ONGC and Asian Paint registered losses.
Foreign portfolio investors (FPIs) sold shares worth a net Rs 456.64 crore on yesterday, showed provisional data. Elsewhere, other Asian markets also ended higher with Japan's Nikkei up 0.38 percent, Hong Kong's Hang Seng 1.55 percent and Shanghai Composite 1.40 percent.
European markets also opened on a positive note, tracking gains in Asian trading amid a slide in the US dollar ahead of US inflation data. London's FTSE, Paris CAC 40 and Frankfurt's DAX 30 all gained up to 1.21 percent in their early deals.
"The market bounced back led by short covering on the starting day of the GST council. Market sensed a bargaining opportunity due to the correction which has happened in the last two weeks while the outcome from the event is likely to be positive," said Vinod Nair, Head of Research, Geojit BNP Paribas Financial Services.
US stocks registered small losses yesterday amid falling oil prices as investors digested a number of corporate results, key economic data and remarks from a key Federal Reserve official.
The market breadth turned positive as 1,905 stocks ended in green, 926 closed in the red while 206 ruled steady. The total turnover on BSE amounted to Rs 3,703.61 crore, lower than turnover of Rs 3,884.29 crore registered during the previous trading session.


text:
Associations between testicular development and fetal size in the pig
Claire Stenhouse, Yennifer Cortés Araya, Xavier Donadeu, Cheryl Ashworth
Royal (Dick) School of Veterinary Studies
BACKGROUND: Impaired reproductive performance is the largest contributing factor for the removal of boars from commercial systems. Intrauterine growth restricted piglets represent 25% of the total number of piglets born and have impaired reproductive performance. This study aimed to improve the understanding of temporal changes in testicular gene expression during testes development in fetuses of different size. The lightest and closest to mean litter weight (CTMLW) male Large White × Landrace littermates were collected at gestational days (GD) 45, 60 and 90 (n = 5-6 litters/GD).
RESULTS: Testes weight and testes weight as a percentage of fetal weight were not associated with fetal size at GD60 or 90. Fetal plasma testosterone was not associated with fetal size at GD90. There was no association between fetal size and seminiferous tubule area and number, number of germ or Sertoli cells per tubule. The lightest fetuses tended to have wider seminiferous tubules compared to the CTMLW fetuses at GD90 (P = 0.077). The testicular expression of KI67 (P ≤ 0.01) and BAX:BCL2 ratio (P = 0.058) mRNAs decreased as gestation progressed. Greater SPP1 mRNA expression was observed at GD60 when compared with GD45 and 90 (P ≤ 0.05). Lower expression of DMRT1 and SPP1 (P < 0.01) mRNAs was observed in testes associated with the lightest fetuses compared to the CTMLW fetuses at GD90.
CONCLUSIONS: These findings provide novel insights into the expression profiles of genes associated with testicular development and function. Further, these data suggest that programming of reproductive potential in IUGR boars occurs late in gestation, providing a platform for further mechanistic investigation.
Journal of Animal Science and Biotechnology
https://doi.org/Stenhouse Fetal Testes Manuscript
Intrauterine growth restriction (IUGR)
Stenhouse Fetal Testes Manuscript
s40104-022-00678-3Final published version, 622 KBLicence: Creative Commons: Attribution (CC-BY)
Dive into the research topics of 'Associations between testicular development and fetal size in the pig'. Together they form a unique fingerprint.
testicular development Agriculture & Biology 100%
Fetal Development Medicine & Life Sciences 75%
fetus Agriculture & Biology 66%
Fetus Medicine & Life Sciences 58%
Swine Medicine & Life Sciences 58%
litter weight Agriculture & Biology 57%
Testis Medicine & Life Sciences 52%
testes Agriculture & Biology 48%
ISP 2 2017/22 Control of Infectious Diseases
Gally, D.
BBSRC
Swine 100%
Aquaculture 94%
Cattle 91%
Chickens 90%
Stenhouse, C., Cortés Araya, Y., Donadeu, X., & Ashworth, C. (2022). Associations between testicular development and fetal size in the pig. Journal of Animal Science and Biotechnology, 13(1), [24]. https://doi.org/Stenhouse Fetal Testes Manuscript, https://doi.org/10.1186/s40104-022-00678-3
Stenhouse, Claire ; Cortés Araya, Yennifer ; Donadeu, Xavier et al. / Associations between testicular development and fetal size in the pig. In: Journal of Animal Science and Biotechnology. 2022 ; Vol. 13, No. 1.
@article{fe9e6ed5e670465291f617dc286bebf4,
title = "Associations between testicular development and fetal size in the pig",
abstract = "BACKGROUND: Impaired reproductive performance is the largest contributing factor for the removal of boars from commercial systems. Intrauterine growth restricted piglets represent 25% of the total number of piglets born and have impaired reproductive performance. This study aimed to improve the understanding of temporal changes in testicular gene expression during testes development in fetuses of different size. The lightest and closest to mean litter weight (CTMLW) male Large White × Landrace littermates were collected at gestational days (GD) 45, 60 and 90 (n = 5-6 litters/GD).RESULTS: Testes weight and testes weight as a percentage of fetal weight were not associated with fetal size at GD60 or 90. Fetal plasma testosterone was not associated with fetal size at GD90. There was no association between fetal size and seminiferous tubule area and number, number of germ or Sertoli cells per tubule. The lightest fetuses tended to have wider seminiferous tubules compared to the CTMLW fetuses at GD90 (P = 0.077). The testicular expression of KI67 (P ≤ 0.01) and BAX:BCL2 ratio (P = 0.058) mRNAs decreased as gestation progressed. Greater SPP1 mRNA expression was observed at GD60 when compared with GD45 and 90 (P ≤ 0.05). Lower expression of DMRT1 and SPP1 (P < 0.01) mRNAs was observed in testes associated with the lightest fetuses compared to the CTMLW fetuses at GD90.CONCLUSIONS: These findings provide novel insights into the expression profiles of genes associated with testicular development and function. Further, these data suggest that programming of reproductive potential in IUGR boars occurs late in gestation, providing a platform for further mechanistic investigation.",
keywords = "Fetal growth, Intrauterine growth restriction (IUGR), Porcine, Pregnancy, Testes",
author = "Claire Stenhouse and {Cort{\'e}s Araya}, Yennifer and Xavier Donadeu and Cheryl Ashworth",
note = "Funding Information: The Roslin Institute receives Institute Strategic Grant funding from the BBSRC (BB/J004316/1). CS was in receipt of a studentship from the University of Edinburgh. YC was funded by the National Agency for Research and Development (ANID) / Scholarship Program / DOCTORADO BECAS CHILE/2016–72170349. Publisher Copyright: {\textcopyright} 2022, The Author(s).",
doi = "Stenhouse Fetal Testes Manuscript",
journal = "Journal of Animal Science and Biotechnology",
Stenhouse, C, Cortés Araya, Y, Donadeu, X & Ashworth, C 2022, 'Associations between testicular development and fetal size in the pig', Journal of Animal Science and Biotechnology, vol. 13, no. 1, 24. https://doi.org/Stenhouse Fetal Testes Manuscript, https://doi.org/10.1186/s40104-022-00678-3
Associations between testicular development and fetal size in the pig. / Stenhouse, Claire; Cortés Araya, Yennifer; Donadeu, Xavier et al.
In: Journal of Animal Science and Biotechnology, Vol. 13, No. 1, 24, 15.03.2022.
T1 - Associations between testicular development and fetal size in the pig
AU - Stenhouse, Claire
AU - Cortés Araya, Yennifer
AU - Donadeu, Xavier
AU - Ashworth, Cheryl
N1 - Funding Information: The Roslin Institute receives Institute Strategic Grant funding from the BBSRC (BB/J004316/1). CS was in receipt of a studentship from the University of Edinburgh. YC was funded by the National Agency for Research and Development (ANID) / Scholarship Program / DOCTORADO BECAS CHILE/2016–72170349. Publisher Copyright: © 2022, The Author(s).
N2 - BACKGROUND: Impaired reproductive performance is the largest contributing factor for the removal of boars from commercial systems. Intrauterine growth restricted piglets represent 25% of the total number of piglets born and have impaired reproductive performance. This study aimed to improve the understanding of temporal changes in testicular gene expression during testes development in fetuses of different size. The lightest and closest to mean litter weight (CTMLW) male Large White × Landrace littermates were collected at gestational days (GD) 45, 60 and 90 (n = 5-6 litters/GD).RESULTS: Testes weight and testes weight as a percentage of fetal weight were not associated with fetal size at GD60 or 90. Fetal plasma testosterone was not associated with fetal size at GD90. There was no association between fetal size and seminiferous tubule area and number, number of germ or Sertoli cells per tubule. The lightest fetuses tended to have wider seminiferous tubules compared to the CTMLW fetuses at GD90 (P = 0.077). The testicular expression of KI67 (P ≤ 0.01) and BAX:BCL2 ratio (P = 0.058) mRNAs decreased as gestation progressed. Greater SPP1 mRNA expression was observed at GD60 when compared with GD45 and 90 (P ≤ 0.05). Lower expression of DMRT1 and SPP1 (P < 0.01) mRNAs was observed in testes associated with the lightest fetuses compared to the CTMLW fetuses at GD90.CONCLUSIONS: These findings provide novel insights into the expression profiles of genes associated with testicular development and function. Further, these data suggest that programming of reproductive potential in IUGR boars occurs late in gestation, providing a platform for further mechanistic investigation.
AB - BACKGROUND: Impaired reproductive performance is the largest contributing factor for the removal of boars from commercial systems. Intrauterine growth restricted piglets represent 25% of the total number of piglets born and have impaired reproductive performance. This study aimed to improve the understanding of temporal changes in testicular gene expression during testes development in fetuses of different size. The lightest and closest to mean litter weight (CTMLW) male Large White × Landrace littermates were collected at gestational days (GD) 45, 60 and 90 (n = 5-6 litters/GD).RESULTS: Testes weight and testes weight as a percentage of fetal weight were not associated with fetal size at GD60 or 90. Fetal plasma testosterone was not associated with fetal size at GD90. There was no association between fetal size and seminiferous tubule area and number, number of germ or Sertoli cells per tubule. The lightest fetuses tended to have wider seminiferous tubules compared to the CTMLW fetuses at GD90 (P = 0.077). The testicular expression of KI67 (P ≤ 0.01) and BAX:BCL2 ratio (P = 0.058) mRNAs decreased as gestation progressed. Greater SPP1 mRNA expression was observed at GD60 when compared with GD45 and 90 (P ≤ 0.05). Lower expression of DMRT1 and SPP1 (P < 0.01) mRNAs was observed in testes associated with the lightest fetuses compared to the CTMLW fetuses at GD90.CONCLUSIONS: These findings provide novel insights into the expression profiles of genes associated with testicular development and function. Further, these data suggest that programming of reproductive potential in IUGR boars occurs late in gestation, providing a platform for further mechanistic investigation.
KW - Fetal growth
KW - Intrauterine growth restriction (IUGR)
KW - Porcine
KW - Pregnancy
KW - Testes
U2 - Stenhouse Fetal Testes Manuscript
DO - Stenhouse Fetal Testes Manuscript
JO - Journal of Animal Science and Biotechnology
JF - Journal of Animal Science and Biotechnology
Stenhouse C, Cortés Araya Y, Donadeu X, Ashworth C. Associations between testicular development and fetal size in the pig. Journal of Animal Science and Biotechnology. 2022 Mar 15;13(1). 24. https://doi.org/Stenhouse Fetal Testes Manuscript, https://doi.org/10.1186/s40104-022-00678-3


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text:
Twitter On Fire As a 3-Year-Old Kid Wrecks Everyone in Call Of Duty Lobbies
Published 01/25/2023, 8:10 AM EST
Atharv Phadke
A three-year-old might be way better than you in Call Of Duty Mobile, so it's time you gear up your skills.
The past few weeks have been special for CODM fans as they witnessed the best 'in-game' cosmetics. It all started when popular content creator Ferg posted a video from his Team Death Match, showing off the new mythic skin for DL Q33. Interestingly, it wasn't the first time devs took an effort to release such items, as MW2 players complained about their game being too boring compared to the mobile version. We all have seen how creative the designers have been when it came to in-game cosmetics for CODM, so this was bound to happen.
However, after Ferg released the video, a strange event took place. Surprisingly, a three-year-old showed major interest in the game, shocking the world. His dad uploaded the video on the internet, showing off his son's skills despite his young age. And like always, the Call Of Duty community once again shared their appreciation towards him.
Young gamer stuns the world with his Call Of Duty Mobile skills
On January 21, 2023, a video surfaced featuring a three-year-old playing CODM. At first, it felt a bit unreal as that age group was never found glued to such a video game. But after watching the whole video, it was far clear that this kid was special. After all, his movement was much better than 'oldies playing warzone 2,' and it felt different.
Activision Baffles Call of Duty Fans With a Major Mobile Move – "Imagine This Ends Up Being Better Than MW2"
The kid featured a Search and Destroy match, calling out all sorts of names to his opponents. For instance, he shouted, saying "I'll get this kid," a phrase that is generally heard from older players. So, it was evident that the three-year-old had fixed his career, and it was none other than gaming.
It was just a matter of minutes before the video broke the internet, grabbing the attention of millions of fans. They expressed their feelings in the comments section, as it was a rare sighting. Here's what they said.
bro is better than me ☠
— Juan! (@Ju600an82) January 24, 2023
What?!!!hes so good.I can't do that.
— Chefred (@hibachichefred) January 24, 2023
That kids gotta bright future ahead of him
— KingOfThe90s (@itzkingofthe90s) January 25, 2023
This 3 year old moves more than the average dad after work
— Propshub (@ThePropOfficial) January 24, 2023
who needs cheating, just hand the controller to this kid when the game is going south tbh
— TenaciousThunder (@blitz_gear02) January 25, 2023
This is who I'm losing to? lol
— 𝐁𝐮𝐥𝐥𝐢𝐬𝐡 𝐆𝐚𝐢𝐧𝐬 (@AlexInvest37) January 24, 2023
In conclusion, it would be safe enough to speculate that the kid might be grinding for the mythic skins. After all, his dad would not let him spend $100-200 if he did not see what he liked.
WATCH THIS STORY: Dr. Disrespect's best rage moments in Warzone
What are your thoughts about this? Let us know in the comments section.
Atharv is an eSports writer at EssentiallySports. Currently pursuing a Master's degree in Journalism from Mumbai University, Atharv has a keen eye for writing engaging content. He enjoys all kinds of games but thoroughly follows FPS games such as Call of Duty, Apex Legends and Fortnite.


text:
«А́збучная моли́тва» (иногда «Толкóвые áзбуки») — стихотворная азбука, одно из самых ранних древнеболгарских и славянских стихотворных произведений, наряду с «Прогласом к Евангелию». Является особой формой изложения религиозных истин, раскрывая в удобной для запоминания стихотворной форме различные вопросы православного вероучения. Представляет собой акростих на алфавит (азбучный акростих, так называемый «абецедарий»).

Происхождение
Поэтический приём акростиха использовался и до появления «Толковых азбук» у славян, византийские гимнографы следовали ему при написании церковных песнопений и гимнов. Например, азбучный акростих был использован при создании акафиста Пресвятой Богородице, многих кондаков Романа Сладкопевца, канонов Иосифа Песнописца и других произведений византийской духовной литературы.

По мнению исследователей прообразом славянской «Азбучной молитвы» явился «Алфавитарь» Григория Богослова — стихотворение из 24 строк по 12 слогов, каждая из которых начинается с очередной по порядку буквы греческого алфавита. Однако этот греческий текст, в отличие от «Азбучной молитвы», не является цельным произведением, а лишь подборкой нравоучительных сентенций, вроде «плохо быть бедным, но ещё хуже разбогатеть через злое».

Текстология
Известно более 50 списков XII—XIX веков, почти исключительно восточнославянского происхождения. Произведение отражает особенности глаголического алфавита.

Во многих списках, включая древнейший, в заголовке автором назван Константин-Кирилл Философ. В самом раннем известном списке XII века) «Азбучная молитва» помещена как часть предисловия («пролог») к «Учительному Евангелию», составленному в 894 году Константином Преславским. Константин, ученик Мефодия назван «епископом» Великого Преслава в приписке 907 года Тудора Доксова, переписавшего выполненный Константином перевод «Четырёх слов против ариан» Афанасия Александрийского. Древнейшая рукопись XII века копирует непосредственно древнеболгарский оригинал, вплоть до портретного изображения болгарского князя Бориса-Михаила. Только в этом списке «Азбучная молитва» сохранила своё первоначальное местоположение и значение предисловия к сборнику воскресных поучений на евангельские темы.

Содержательно и стилистически произведение тесно связано со следующим за ней прозаическим прологом и вступлением к 3-й беседе. В XIII веке «Азбучная молитва» в соединении со «Сказанием о русской грамоте» и выписками из пространного Жития Константина-Кирилла Философа вошла в состав дополнительных статей, сопровождающих Палею толковую хронографическую) и посвящённых истории создания славянской письменности. С XV века помещается в рукописях как самостоятельное сочинение и часто сопровождается сведениями о начале славянской письменности. В ряде списков XV—XVI веков «Азбучная молитва» вместе с прозаическим предисловием и 1-й беседой Константина сопровождает «Учительное Евангелие» патриарха Каллиста (или Филофея). В сборниках XV—XVIII веков «Азбучная молитва» часто помещена среди азбучных стихов — «толковых азбук».

Источниковедение
Произведение написано не позднее 893 года.

Указание на авторство Константина-Кирилла Философа, отождествлённого исследователями с первоучителем славян, породило в славистике споры об атрибуции произведения, в которых по-разному интерпретируется и его содержание. К числу сторонников авторства Кирилла принадлежат М. П. Погодин, И. И. Малышевский, И. Я. Франко, Е. Георгиев.

Более распространённой является точка зрения, согласно которой «Азбучная молитва» — лирическая исповедь Константина Преславского. К этому заключению пришли В. М. Ундольский, О. М. Бодянский, П. И. Шафарик, епископ Антоний (Вадковский), А. И. Соболевский, А. Вайан, Э. Г. Зыков, К. М. Куев. В работах Зыкова, Куева, Г. Попова прослеживается стилистическое (а иногда и дословное) сходство «Азбучной молитвы» с несомненными творениями Константина Преславского («Учительным Евангелием», Службой архиепископу Мефодию, циклом триодных трипеснцев). Атрибуция Кириллу восходит к замене оригинального заглавия словами «Сице рече святый Кирил» при извлечении из полного текста.

Структура
«Азбучная молитва» представляет собой акростишную молитву, в которой каждый стих начат с очередной буквы славянского алфавита ('ακροστιχίδα κατ' 'αλφάβητον). Стихотворение написано 12-сложным размером — «политическим стихом» (στίχος πολιτικός). В 40 стихотворных строчках реконструированного текста преобладает цезура после 5-го слога (5+7), в двух случаях она делит строку на 7 и 5 слогов, а в двух стихах — на 6 и 6. Образцом метрики и акростиха для «Азбучной молитвы» послужили «Мысли, написанные одностишиями» Григория Богослова — 24 строчки, образующие азбучный акростих и начинающиеся стихом «'Αρχὴν 'απάντων καὶ τέλος ποιοῦ θεόν». Это изречение перефразировано Константином Преславским: «Добро есть от Бога начинати и до Бога коньчавати яко же рече етер Богословьць Григор». С него Константин начинает своё прозаическое вступление к «Учительному евангелию».

Содержание
По содержанию это молитвенное обращение автора по завершении труда (сборника воскресных проповедей) к Святой Троице с похвалой крещению славянских народов («Летить бо ныне и словеньско племя / К Крещению обратишася вьси / Людье твои нарещися хотяще») и оценкой своей работы как продолжения дела славянских первоучителей («Шьствую ныне по следу учителю. / Имени ею и делу последуя, / Яве сътворю еваньгельско слово»). «Азбучная молитва» отражает идеи IX—X веков, связанные с крещением Болгарского государства при князе Борисе-Михаиле и созданием славянской письменности братьями Кириллом и Мефодием.

На Руси
«Азбучная молитва» была широко распространена в древнерусской письменной традиции, о чём свидетельствует большое количество её вариантов. Учёными обнаружено и опубликовано 43 древнерусских списка «Азбучной молитвы» XII—XVII веков. Из них 23 представляют собой извлечение из полного текста с аттрибуцией Кириллу.

Текст «Азбучной молитвы» был обнаружен и впервые опубликован в 1825 году М. П. Погодиным в приложении к переводу на русский язык книги Йосефа Добровского «Кирилл и Мефодий, словенские первоучители». Погодин поместил текст двух списков — псковского 1494 года и из сборника Волоколамского монастыря XVI века. Критическое издание текста по всем спискам представлено в книге W. R. Veder «Utrum in alterum abiturum erat?».

Варианты «Толковой азбуки»
Приведённые ниже тексты молитвы переданы современным русским алфавитом, за исключением первых букв акростиха, с сохранением звучания текста оригинала.

«Аз словом сим молюся Богу»
Текст обнаружен среди рукописей бывшей патриаршей библиотеки в сборнике, принадлежавшем патриарху Никону.

Аз сло́вом сим молю́ся Богу:
Бо́же, всея́ твари́ Зижди́телю,
Ви́димым и неви́димым,
Го́спода Ду́ха посли́ Живу́щаго,
Да вдохне́т в сердце́ ми сло́во,
Еже бу́дет на успе́х всем,
Живу́щим в за́поведех Ти.
Ѕело́ бо есть свети́льник жи́зни
Зако́н Твой, свет стезя́м,
Иже и́щет ева́нгельска сло́ва
І про́сит да́ры Твоя́ прия́ти.
Ко креще́нию обрати́шася вси́,
Лю́дие Твои́ нарещи́ся хотя́ще,
Ми́лости Твоя́, Бо́же, про́сят зело́.
Но мне ны́не простра́нно сло́во даждь,
О́тче, Сы́не и Пресвяты́й Ду́ше,
Прося́щему по́мощи от Тебе́.
Ру́ци бо свои́ выспрь возде́ю при́сно,
Си́лу прия́ти и му́дрость у Тебе́.
Ты бо дае́ши досто́йным си́лу, ипоста́сь же вся́кую цели́ши.
Упова́ние всех конце́в земли́.
Фарао́на мя зло́бы изба́ви,
Херуви́мску ми мысль и ум даждь.
Ѡ, Честна́я Пресвята́я Тро́ице, печа́ль мою́ на ра́дость переложи́.
Целому́дренно да начну́ писа́ти
Чудеса́ Твои́ преди́вные зело́,
Шестокрыла́тых си́лу восприиму́.
Ще́ствую ны́не по сле́ду учи́телю, и́мени его́ и де́лу после́дуя,
Ѣ́вным сотворю́ ева́нгельское сло́во, хвалу́ воздая́ Тро́ице в Божестве́,
Ю́же пое́т вся́кий во́зраст, юн и стар свои́м ра́зумом,
Ѧзы́к нов, хвалу́ воздая́ при́сно Отцу́, Сы́ну и Пресвято́му Ду́ху,
Ему́ же честь и держа́ва и сла́ва
от всея́ тва́ри и дыхания
от вся ве́ки и наве́ки. Аминь

«Аз есмь свет миру»
Текст из рукописного «Сборника слов и поучений», который датируется серединой XVII века, хранится в библиотеке МГУ.

Аз есмь свет ми́ру
Бог есть пре́жде всех век
Ве́даю всю та́йну в челове́це и мысль
Глаго́лю лю́дем зако́н Мой
Добро́ есть творя́щим во́лю Мою́
Есть гнев мой на гре́шникы
Живо́т дах всей тва́ри
Ѕло есть законопресту́пником
Ни на чем Зе́млю Мою́ утверди́х
Престо́л Мой, И́же на небесе́х
І шед на а́дова врата́ сокруши́х и ве́рея желе́зная сломи́х
Ка́ко лю́дие беззако́ннии не сотвори́сте во́ли Моеа́
Лю́дие Мои́ непоко́рные
Мы́слете на Мя зла́а
Наш еси́ Бог и засту́пник
Оны́ Моя́ призову́ язы́ки и ти́и Мя просла́вят
Поко́й дах всей тва́ри Свое́й
Рече́те Ми сло́во не творя́щие во́ли Моея́, и не услы́шу вас
Сло́вом Мои́м вся́ утверди́шася
Тверда́ рука́ Твоя́, Влады́ко
Фарао́на потопи́х в Чермно́м мо́ри
Херуви́ми слу́жат мне со стра́хом
Ѿве́рзу рай христиа́ном
Ци не дах вам пи́ща в пусты́ни
Червь и огнь угото́вах на гре́шникы
Шу́мом и попали́т дубра́вы
Щито́м вооружи́хся на брань Го́ры взыгра́шася явле́нием Мои́м
Ыорда́нь освяти́ся креще́нием Мои́м
Е́ресь погуби́х
Ю́гом ве́тром разве́ю всю́ вселе́нную
Ю́же Мя проро́ци пропове́доша и апосто́ли е́же о Мне научи́ша.

См. также
 Черноризец Храбр
 Преславская книжная школа

Примечания

Издания
 Добровский Й. Кирилл и Мефодий, словенские первоучители : Историко-критическое исследование / Пер. с нем. М. П. Погодина. — М., 1825. — С. 109, 151
 Срезневский И. И. Памятники. — С. 191
 Антоний, еп. [Вадковский]. Из историй христианской проповеди : Очерки и исследования. — 2-е изд. — СПб., 1895. — С. 161
 Соболевский А. И. Церковно-славянские стихотворения IX—X вв. и их значение для изучения церковно-славянского языка // Тр. 11 Археол. съезда в Киеве. — М., 1902. — Т. 2. — С. 28—37
  (привлечено наибольшее число списков)
 Куев К. М. Новооткрити преписи на Азбучната молитва // Palaeobulgarica = Старобългаристика. София, 1979. Кн. 4. С. 26—33

Литература
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Ссылки

 Азбучные стихи (азбучная молитва)
 Середа Е. В. Аз, буки, веди… Материалы к уроку по славянской азбуке. — Учительская газета, № 17 от 22 апреля 2003 года

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Памятники древнеболгарской литературы
Литература Древней Руси
Произведения IX века
Православные молитвы