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A superb inside designer should not merely have knowledge concerning things but about the stores where in fact the necessary things could be purchased at inexpensive rates. Starting out as a freelance graphic designer takes longer than being creative and talented inside your area. A graphic designer that has a little company should avoid quite a few of errors. You certainly have to become proficient at style, but that is not adequate to take you get through the rivalry that's characteristic of freelancing. It could be well worth thinking of sending a layout that is vintage that is wonderful .
You ought to be structured and prepared your job will be wrapped up to really go. Yet another procedure would be to calculate contingent on the job. An interior designer has to become alert to everything he wants to enhance.
Visit, if you would enjoy additional template choices and review their possibilities. Investigate the options to obtain what you are hunting for. There's option to get the facts about supplier and buyer with the credit score span and also repayment information. There is substitute to incorporate the name of the seller organization along side the client with payment information and also the date in which it ought to really be acquired.
You're able to look precisely the way that your invoice looks here. An invoice should be designed for confidence and the safety on the section of the designer. Order Status bill will be generated dependent on your buy status just.
From employing invoice template, you can create your invoices. You will need a statement that is likely to create your company is simple to use and look expert. Simply tell us if you're struggling with creating a statement to talk to your own client and we'd like to produce your desire's statement for absolutely at no charge! Zoho bill is an online invoicing app created by company software big Zoho. Zoho Invoice carries numerous templates that are reactive to make it possible for one to make statements that are beautiful .
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The invoice shouldn't comprise fees that you have discussed with your customer. You'll come across no cost bill Template out of our site, if you're also on the watch for a few professional equipped alongside free of cost invoice to ready your very own small business invoice. Because of this, you may make use of the statement to create the penalties and citizenship incentives that you offer understood. It auto-generates bills of your own time therefore you may get paid for your work effortlessly. Invoices are among the most essential documents for enterprise owners. Since they help customers to comprehend what they have been currently looking for invoices are attractive to customers. Having a template it's possible to make yourself a professional appearing.
Your statement needs to appear easy and tidy to see. S O statements are vital for practically any kind of business. A person may receive a wide selection of invoices .
A word of information isn't to really go on the styles you select. If your small business name will not obviously define the sort of product or service you supply, then you need to be certain you have a label line or slogan. Giving just about each lineup a title that is different is very likely to make editing somewhat more easy. Hosting options and domain Names are fundamentally easy.
You are actually leading the provider house to your possibility or even a contributor After you supply the e mail addresses of one's buddies. For somebody who has much grasp of the insurance policy plan merchandise, locating advice may possibly be considered a tricky encounter. You are going to be shown recipient data . For the account page it's possible to make a Google areas listing for the own organization. The approach that is best to discover them will be always to do a look for the top article submission sites, although there are a lot of article methods to pick from.
You understand which isn't about applying a method in regards and that which person is appropriate. If your site is functioning to a Unix-based working platform (for instance, Linux), odds are your internet server affirms the PHP scripting terminology. Your site will take a critical nose-dive if you're doing. Check out each the optimization approaches to each search engine that you simply intend on submitting your website to. For instance, if your internet site will be computers, then create. Building an web site is straightforward, even for non-IT women and men.
To be able to bargain with temperament and all the stream of development, matters want to alter Everything progresses. Which means you're likely for to pay a portion of it. You need to just accept the notion that publishing isn't anything besides the introduction of an record in your own computer to get a particular use to begin researching your imagination. Any concept could possibly be good 1, however, try to think. Experience the drawn-out tail for example sub-tails and you're not likely to runout from articles generation thoughts.
Sites contest sites, and purchasing comparison sites, to say a couple of. For your massive area, you're very likely to be doing something different so the template might perhaps well not be considered described as a practical element for you. You're innovative and you may produce your own articles without needing to utilize various peoples works since the foundation for your own content. Make an effort to include personal experiences which is regarding one's website entry's subject. Additionally, there really certainly are a number of online business chat forums and company Blogs where it's possible to post opinions.
As a way to attract the attention of search engines, then you might require to make an suitable number of articles along with information. The higher your degree of attention, the more simpler it is to allow one to receive your caliber material submitted to your own blog. Additionally you will put here the articles of your website. An individual can get many different inquiries and want to find more about the insurance policy product, forms of dangers, and policy details etc.. They can ask additional questions unique for the item and plan. He could use live conversation receive replies in real life and to contact a specialist. Intricacy along with the applying interface of the applying functionality additionally has an crucial part in picking on the general customer engagement encounter.
You may want to store your file using a brand new name at the occasion you wish to alter your gift tag. You might well be wondering what documents you're able to talk about with you right the following… this really is very straightforward. You are able to make your text and following that it will be possible to copy and then paste the text in the cells. Fonts possess an influence on the way your document will appear. Despite the fact that attention will be grabbed by a font that is fashionable it's still a fact that you have to take into consideration the legibility of one's own words.
An internet typical page design is produced by utilizing tags or meta tag codes. You might need to make use of templates for developing your letterhead, in case you want a straightforward and quick procedure. This sample credit repair letter template can be a superior beginning. The plan layout is going to be your guide on which to set your content in every webpage that is internet.
No matter type of organization you've got, be sure your letterhead demonstrates your enterprise value effectively. You speak about the benefits of listing their corporation and may also proceed to every company. You have the ability to delight within a firm for quite a very long time in case you don't cease employing the processes.
You're able to download templates on line. You can find a good deal and plenty of games that are printable online. It isn't feasible to succeed online with out having some type of promotion through electronic mail.
A great deal of men and women would like to obtain a occupation. So in the event that you prefer an advertising job, as an example, look at taking a certificate application. Resumes have traditionally become the major ticket to navigating the work marketplace. You may possibly have known about chronological and practical arrangement. You may locate all our resumes that are entirely free to download below. Hybrid resumes choose the very best faculties from every of the formats.
You're able to easily tailor made the mix resume illustrations to satisfy your circumstances. Contemporary restart examples have their traits as it pertains to format and layout, since you often see. These instances represent an range of letters you might work with throughout your job search. You need to at all times assess the task description to determine if the organization desires a specific document style. Even although you are a amazing worker, however you are unable to present the important points on your resume you can miss out the opportunity. Be certain you get the advice you're searching for. You will need to improve it, although you could possess a foundational resume which articulates the advice, states Heifetz.
For instance, include it at the experience department If you've got expertise having a form of software. Add your adventure you have. If you get yourself a very good work experience, you may utilize the operational in case you've got career openings and you are changing careers and the chronological format. Give you. Skills It's important to remember that expertise are an extremely various thing to particular qualifications. In addition, in case you have some tough abilities and they truly are associated with the positioning you were employed it is highly recommended to bring capabilities that are this. When it highlights your capabilities instead of work history, then it is better for you personally if you have openings in your employment.
Adhering into the restart celebration is very useful in case this app's content must be more refreshed. You've got on your own resume as you most likely know, whether you purchase a work interview or maybe not will depend heavily upon the info. Give your very best knowledge to the company to persuade the manager that you're a superior candidate which has a skill but you may possibly well not have jobs or job in various fields. An manager could be checking to see whether you have increased in title. Remain educated about a large variety of tasks that are ever-changing and workshops and events Freelancers who wish to stay in a hybrid market need to show inside their field.
Expert knowledge or work history is probably the section of your resume. You're ready to read concerning the worth of hints here. The target of the resume is to secure you a meeting. Retrieves a specific process you've created.
In the event you'd like to pick the best sample resume format, you can check on occupation internet sites and discover what professionals at the industry, specialist knowledge and comprehension are using. Take a peek at the following to secure you comfortable with the likely formats to utilize for your CV or restart. There you have the 3 most common formats when browsing for the most useful format for restart. Your resume should be composed by you in an ordinary format. You have arrived at the site, if you're on the lookout to get a combo format resume template.
There are three primary sorts of restart templates. You will not need to be concerned though since there are uncomplicated resume templates edit and to create utilization of. You might utilize the complimentary resume templates, for increased end result. First find the very top template that you just opt for. There's no cookie-cutter template which will succeed for your private career history and intentions it can be challenging to spot what advice is definitely better without getting to know you 39, include. It's straightforward to obsess over the design and also the way your resume looks.
The template has turned in to an remarkable design and style. Based on your own situation, you may use a hybrid, or alternative forms of resumes. It's all-important to change education system based to period condition as well as the advancement of culture. Applicant monitoring techniques have to take a posture. Tailor your resume contingent on the job which you are employing, meaning do not compose an application if you do not have a certain company. Application Strategies The job application represents the exact first hurdle for the ex-offender hoping to explain an absence from your job industry. For instance, the summation section needs to be prepared at the exact first person.
Don't be afraid to attract a dash of humor, if you might be funny. Gratefulness could be your life which we hold within our handsbecause if we're not grateful, afterward however much we now have as we'll often wish to have some thing else or something 44, we won't be joyful. It's common anyhow. Providing thanks is one of the most effective ways there is to optimize your wellbeing. Give thanks to your little and you will find alot.
People have an inbred reaction to mimic exactly what other individuals are doing. In order that it can be used by them for his or her tax-deductible varieties you've to present the statement of these help. Letter-writing within the example of contribution thank you letters need to own a touch. Additionally make sure that you do not neglect to mention that acknowledgement receipt correspondence is a document that is considerable that the business may use to acquire benefit. You can also navigate my selection of Inspirational Quotes. Reading gratitude quotes may be a proven approach to remind your self that you have alot to be thankful for. It's likely to likewise search my sizable variety of amusing rates.
An example was given here as a way to offer a better comprehension of just how such a letter consists to you. This will make it possible for you to learn just how to write a thank you letter. While it is going to serve the reason of being the cornerstone, it is preferable to compose a letter working with a template as a principle, since this may make sure your letter is more legitimate and private in its own tone. Then your templates would be the perfect means to make a permission slide. There is absolutely no regular arrangement for writing acknowledgements, simply that the arrangement needs to suit the remaining of your research paper Dissertation acknowledgements case in point.
No-mind is the real ways to live, the authentic means to comprehend, the method to be. Whenever you have testimonials set those testimonials under this product. You receive the testimonial plus also they don't really should do any job. Their testimonial is special. See any high-value and you're going to observe that they're loaded with customer testimonies. You can not have buyer testimonies that are adequate.
Truly love life, and you may discover you do have more of it. Therefore as to bring that life gives, you ought to truly appreciate what you have. Nearly all people do not will need to select the moment (or accept the potential guilt). In the brief time you've already been right here, you helped to make objects run effortlessly. It absolutely was just one of the roughest times in my own private lifespan. In fact, their work really is a lifesaver, and thus, valuable for women and men in the society. If you feel unappreciated or miserable or in your private life, there isn't any alternative than simply interacting.
Be grateful once you do not understand something because of this offers you the opportunity. You'd be helping us inside our advertisements campaigns. In future, should you want any assistance firms may certainly arrive to help you.
You are going to need to tailor them to meet your conditions. Anytime you will construct a society which will work, you have must start from your system and also nature. The spirit of appreciation is just actually a strong energizer. Meditation is actually a solid manifestation of love also it may perform wonders . For this reason, there is an intrinsic disbelief in virtually any advertising material which develops from you. There is absolutely no loneliness like theirs.
Ensure you meet your assurance so youthought for increases that are far superior, and're taken seriously later on. Note there is a guarantee to perform and to reside until the salary amount you're being awarded yearly. You still receive the money. By going into the needy people the complete dollars has seen that a motive plus they will have been in a position to go back to regular living. While doing work for an origin, it is perhaps not always simple to collect capital and when you've secured a contributor who's ready to donate to your origin, it is not just proper but also plain nice to thank them all for helping with the assignment which you're buying for. It really is important your letter mentions the way Whilst thanking a person who has made a donation to a cause that you're searching for. Make use of this sample to guide the procedure for correspondence composing, regardless of what type of event you are devoting your sponsors for.
Trust in me, acknowledgement is actually a thing that is strong. State name of someone who that you would like to mention within an acknowledgement. Usually, acknowledgements vary dependent on. It is reportedly the recognition of the existence of something or some truth. Note however also you also must tailor your acknowledgements to suit your circumstance and that each project is different. A two-page acknowledgement runs the possibility of producing your reader shed interest and is too long. Special acknowledgment for donors is actually really a step to make sure that their elevated sum of service is recognized.
It really is essential to admit acts of kindness and support while it may be hard to compose sympathy thanks notes even though you're grieving. You could also express your admiration to your nearest and dearest, family and friends who supported you at the length of creating a thesis. Some folks, for some reason do not be afraid to write a dedication in the place of an acknowledgement.
Nobody will surprise you even. It is appropriate to ship an acknowledgement card In the event you get yourself a greeting card. Inside the wake of your loved one's departure, you're likely to get yourself a variety of familiarity cards and notes.
When a donation doesn't always have a legal email you will possess the ability to publish the recognition. For fundraising letters, clearly say the way it'll be properly used. Figuring out whether a donor is earning their very first donation or their fifth term is very crucial in being aware of what things to get in your thank you letter.
However donation has been, donors wish to feel like you appreciate them beyond the variety of what it is they are able to donate financially. Whatever the size of the present, they want to be aware of their involvement things. Due to the fact she desired to match with the person who had written this kind of letter that was gorgeous, the organization was called by the delighted donor.
These two are fantastic ways for donors to find out a lot more. For instance, if donors provide more than a pre determined number, their names can be recorded in a particular spot on your own site. Just like donors gift donors desire to know how their gift can be used and also how it's helping you supply superior and more library solutions on your area.
An email letter is ideal for linking for your site and newsletter. There really are plenty of concerns you could set at a contribution identification correspondence, but the significant thing you ought ton't forget would be to relay all the information of the donation and its specifications for a very clear and transparent transaction. An identification letter is comparable to a thank-you be aware. Lots of the sample recognition letters have been attached under the material. Additionally, you can also work together with you to learn more.
Whether you've got a thankyou department that is detailed or not believe, it's still recommended to compose a succinct note about the back of the app thanking each of your guests that obtained the ability to come to your wedding ceremony and helped to produce your evening unique. Good notes will continue to keep you on track when ensuring you cover whatever you prefer to enjoy, by way of instance, the title of each man and . It's possible to compose an awesome acknowledgement observe .
Besides revealing gratitude, the letter will probably likewise cite that the intention behind the contribution. It's critical to add your reason. It's crucial by giving a explanation of why you're producing it to initiate the letter. To prevent that issue, your letters need to become supporter-focused. Additionally they act as a listing of the gift and can be utilized for taxation reasons. Several recipients may be addressed by These letters. That has to be acknowledged with an individual reply, if you get a more lengthy sympathy letter.
You will also involve individuals that you help within the acknowledgement strategy, although you may not just customize your letters. There could be several motives to compose a thank you for letter of admiration. Ensure that the correspondence is not vague or overly long. There is An donation acknowledgement letter used by the recipient of the contribution to guarantee that the sender they have received either the amount of cash or any help being extended with the individual that gave the donation. Donor acknowledgement letters are, also in a variety of approaches, the very first measure in the direction of donor retention. You may receieve a answer that is complete .
Obtain the news that is great out there for everybody. It is possible to even consist of appreciation reports from various directors or workers in your speech. For a number of folks, composing a poem is somewhat more easy than for others.
Beneath, advice is presented around the perfect way to compose acknowledgements. If close good friends and relatives do not feel like partying all evening and wish to examine their day to day issues, track down some other group of good friends! That you really don't need to thank you each of your friends and each individually! Loved ones are enthusiastic about a cause and if individuals visit their buddies they may look at encouraging. There's more than one way to phrase Thank you so much to my parents, so my pals along with my thesis adviser", however, the level of standard procedures to term which is so much more streamlined compared to variety of theses that the pigeon hole principle relates to illustrate numerous persons are producing exactly the exact paragraphs within their acknowledgments. That indicates that you might think taking a compliment should be rather uncomplicated. Furthermore, the perfect thing concerning figuring out just how to accept compliments is it will give you the opportunity to see yourself as others see youwhich is the most probable pretty incredible.
Words might be shifted to fit your individual demands. At times it could be demanding to discover the words that are ideal to state about somebody that means a lot to you. Words of thanks isn't only excellent manners, nevertheless also the perfect activity. Thank you're really just a phrase which is used so usually, when it is genuinely and profoundly indicated by you toward an individual, it truly is oftentimes really difficult to demo appreciation. If you are browsing to utilize in your funeral thankyou cards, you will see examples under.
Reading gratitude quotes might be a proven method to remind your self that you simply have too much to be grateful to. It's likely to hunt my large group of amusing estimates. You may also navigate my variety of Inspirational Quotes.
You prefer to send out your condolences to the family. On the side, can be a feeling of needing to help the individual actually want and also understanding precisely the issue. Alfred Painter Gratitude is the biggest of virtues, however, also the parent of all the many others. Show your appreciation and make it private. Daniella Whyte Appreciation is really a issue that is great. Note nevertheless that every job differs and you must tailor your acknowledgements to satisfy your precise circumstance. An excellent acknowledgment goes that the excess mile to describe an author is grateful.
Possibly the acknowledgments site is a location it's likely to engage in this up only just a small. If you might have questions or any comments, you should get in contact all of us. Messages can work. Pick the mail merge file you'd really want to utilize for your own present Acknowledgment. After the request was created it truly is challenging to stay to get a roundrobin request, particularly on high in correspondence.
Acknowledging an individu assistance can make them feel fantastic and let them know that you simply aren't hoping to carry the credit all yourself. The advantages of gratitude are immense. You will possess the capacity to publish the 19, if a donation will not have a legal e mail. Share something positive regarding the individual who gave one of the present. You chose me personally the perfect present. You are quite a blessing. You're nothing Beneath a boon from God!
Since they don't really feel valued A great deal of people have gone almost mad. There's always somebody who needs something. One of the issues on Earth is possessing your favourite food attracted to you. You publish your very own certainly one of some sort communication to definitely show your admiration and may get ideas from the list below. You have some thoughts of what things to publish in your thank you notes, also you've seen that you just may express gratitude that is sincere and meaningful in a couple lines, and it will be troublesome to first begin. It is necessary to keep in mind that romance is available from many types. Just a tiny love goes a very long way.
It isn't possible to experience glad and miserable in exactly the same second. So a range of people have become the custom of exclusively sending email, and therefore it lovely to have a note in the mail. You need to really have read my mind as your gift isn't simply what I needed. The simple reality remains, when it might feel as it is a frame of mind it is a. All you must do is clear the mind and provide yourself a few moments to presume . Concentrate on discussing connect to theirs. Don't forget that the advice above, and don't ever forget the sensation you'd love to communicate and the solutions that you would like to supply.


text:
How to speak like a data center geek: Artificial intelligence
By Julia Gabel, Thu 11 Jan 2018
It's time to take on artificial intelligence (AI) in our "How to Speak Like a Data Center Geek" series.
Why now? Because even though it's been around for six decades, AI has rarely been hotter.
In Equinix's 2018 predictions, we forecast an imminent AI breakthrough into the mainstream. Already, AI powers advances like algorithmic trading, autonomous cars, even online shopping. And as digital capabilities advance, so will the capabilities of AI.
As fast as it's moving, AI isn't approaching the dark vision presented by popular culture (HAL 9000, meet The Matrix) or the expectations of more optimistic thinkers who say it will usher in a new era of human civilization … yet.
But who knows what's ahead? Maybe that's a question for Siri. In the meantime, this Geek entry is here to bring you a little AI knowledge.
Just like in the definition of HAL, (Heuristically programmed Algorithmic computer), algorithms are at the foundation of AI.
At the most fundamental level, they are mathematical instructions that tell computers what to do.
But in AI, those instructions aren't always explicit, "Do X or Y"-style commands. Instead, algorithms can be used to set up rules and systems that enable a computer to learn.
Before we discuss neural networks, it's useful to refer to the quick definition of artificial intelligence from Webster's: "The capability of a machine to imitate intelligent human behavior."
To imitate human behavior, AI needs to be able to solve problems, and a neural network is one way to do it.
A neural network is patterned after the workings of the human brain because it breaks computer learning into tiers of comprehension that connect and build on each other. Say the task is to tell the difference between the written numerals 1, 5 and 9.
The first tier receives the raw data and makes findings, perhaps noting very basic similarities and differences. Then, it passes on the relevant information to the second tier.
That second tier works with those findings – rather than the raw data used at the first tier – to make more complex learnings. It then passes on that info to the next tier, and so on until the task is completed.
Machine learning and AI are often used interchangeably, but machine learning is an AI subcategory, not the whole.
Specifically, machine learning uses algorithms to analyze data, draw conclusions and make a prediction or finding. As discussed in the algorithm section above, a key here is that the machine learns without being specifically programmed for a result, but by learning from "experience."
This experience is gained by starting with models that predict various results, followed by analysis of related data, then adjustments (learning) by the machine of the model's initial assumptions, based on the actual patterns and results uncovered.
A famous example is from machine learning pioneer Arthur Samuels, who programmed a computer to play tens of thousands of games of checkers against itself and learn what board positions were advantageous. The program then used that knowledge to beat human opponents.
Like machine learning is a subcategory of AI, deep learning is a subcategory of machine learning.
Key differences between machine learning and deep learning are the greater amount of data processed and far more complex algorithms used in deep learning.
It's fair to say the advent of big data and unprecedented computer processing capabilities enabled the development of deep learning.
Like its name implies, deep learning is, well, deeper than plain old machine learning. By using large neural networks, enormous data sets and hugely powerful computers, deep learning takes on real-time tasks that are far more complex than playing checkers.
In a deep-learning demo at a lecture in China, a Microsoft executive used a speech program that transcribed his spoken words into English text, then into Chinese text, then simulated his voice saying the words in Mandarin. That's deep.
Interconnection in AI
To function, AI needs direct and secure interconnection between a range of users, cloud applications (analytics, storage, etc.), machines, and data sources.
And this interconnection needs to happen instantly, with the various counterparties as geographically close to each other as possible. The Equinix Cloud Exchange (ECX) Fabric enables this kind of interconnection in more than 25 metros in North America and EMEA, and it will be expanding across Equinix global locations over time.
Article by Jim Poole, Equinix Blog Network
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redpajama_set_name: RedPajamaCommonCrawl


Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois – Make the most of your space with these decorating ideas to get Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois from leading designers. Duplicate these fashionable Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois wall decor ideas to bring your empty walls to life. To get you motivated, here's our pick of ideas out of houses we have search. These simple Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois prove that you don't require a great deal of square, Add instant style to any decor with decorating ideas that call to get a small imagination. Just because you live in a Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois apartment doesn't indicate you have to settle for boring, pint-sized furniture. And if you've discovered the perfect Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois of your fantasies, minute spaces can fold up and down and a number of other space saving furniture cases and thoughts. Here are Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois ideas and tips that will assist you create a bedroom area which could be small in square footage, but is large in style. Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois can have a large effect with the right design. Renting a Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois can get extra catchy with odd nooks and corners. Use light, crisp colors to combat unique attributes like lower ceilings. Bright whites look luxe in any sized room, and even turn this slanted-ceiling kids' room to a spacious play zone. Put the'big' to a Custom Pole Barn Home Plans Elegant Custom Barn Home In Jerseyville Illinois with bold pieces and powerful patterns. When decorating with artwork that wows, neutral bedding is a must. A little wallpaper, paint, or a few colorful accents may make a massive impact in your home. You can tackle each of those ideas in one day, though the results will seem as though it took way more time to pull away. Shade is a powerful design tool in decoration, in addition to in interior design that's the art of composing, and coordinating colors together to create a fashionable scheme on the inside design of the space. It is essential to interior designers to acquire a deep encounter with colours, understand their psychological effects, and understand the significance of every color in various locations and situations so as to produce appropriate combinations for each location.
Combining colors together could lead to making a state of mind as seen from the observer, and could eventually lead to negative or positive effects on them. Color mix make a tiny room look bigger or smaller.So it's that the Interior designer livelihood to choose appropriate colors to get a location in ways people want to feel and look in the area.
One of the most essential matters when planning house plan are the traffic patterns.You have to thinking more detail concerning the way to creating a plan for each days activity from start to finish. That is all about discovering which way is your fastest route, what areas to strike first to prevent traffic and delays, so we are able to achived efficiency. While that could be a stretch from house design and preparation, the idea of traffic pattern planning is the underlining focus that coincides with creating the flow or traffic movement in your property. Among the greatest way to effectively ascertain home plan traffic patterns would be, you need to imagine yourself actually moving throughout the house, multiple posibbility can be created via the visualitation. Do not forget to dedicate a minimum amount of room to traffic areas. Planning is take the significant role, so valuable square footage can be dropped if you do not plan accordingly. The most efficient design involves producing the illusion of hallway traffic patterns or passages using furniture placement. This can be seen in open floor plans. They utilize a minimum number of interior walls to separate rooms. It involves a little forethought from the contractor and designer, but expert active preparation eliminates traffic pattern difficulties and furniture structure for the homeowner. You should keep the dimensions of hallways and corridors should to a minimum. Make certain that you also keep halls brief in distance.


text:
package com.polyvi.xface.exceptionReporter;

import android.app.Application;

public class XDroidApplication extends Application{

    @Override
    public void onCreate() {
        Thread.setDefaultUncaughtExceptionHandler( new XExceptionReporter(this));
        super.onCreate();
    }
}

redpajama_set_name: RedPajamaGithub


HomeAlt FashionStreetwear for the Uber Fashionable Geek.
Popular Naughty is a streetwear company that specializes in that kinda dive bar, burlesque club, vintage, punk rock in yer frackin' face designs We are toying with bringing the online shop here. Hey, if it is good enough for Miss Mia Vixen, it should be good enough for anyone.
Tim Curry's OTHER hit song.


text:
class Player :
	public Entity
{
private:
	//Meters per second
	float m_acceleration;
	float m_maxSpeed;
	float m_throwStrength;
	float m_blendTimer;
	bool m_isAiming;
	bool m_playerIsRotating;
	Entity* m_ball;

	Ragdoll* m_ragdoll;
	Entity* m_grabbed;
	DirectX::XMVECTOR m_carryOffset;
	DirectX::XMVECTOR m_anklePos;

	DirectX::XMVECTOR m_lookDir;
	DirectX::XMVECTOR m_upDir;
	DirectX::XMVECTOR m_rightDir;
	DirectX::XMVECTOR m_newPlayerDir;

#pragma region soundvariables
	bool m_hasBeenThrown;
	irrklang::ISound* m_thrownSound = nullptr;
	irrklang::ISound* m_walkingSound;
#pragma endregion

	float m_chainSoundTimer;
	float m_timeSinceThrow;
	bool isAbbington;

public:
	Player();
	~Player();

	int Initialize(unsigned int entityID, PhysicsComponent* pComp, GraphicsComponent* gComp, AnimationComponent* aComp);

	int Update(float dT, InputHandler* inputHandler);
	int React(unsigned int entityID, EVENT reactEvent);

	//Returns the old value
	Entity* SetGrabbed(Entity* entityPtr);
	float SetMaxSpeed(float speed);
	float SetAcceleration(float acceleration);
	DirectX::XMVECTOR SetLookDir(DirectX::XMVECTOR lookDir);
	DirectX::XMVECTOR SetUpDir(DirectX::XMVECTOR upDir);
	DirectX::XMVECTOR SetRightDir(DirectX::XMVECTOR rightDir);
	void SetAiming(bool isAming);
	void SetBall(Entity* ball);
	void SetRagdoll(Ragdoll* ragdoll);

	bool stateExists(int animationState);
	void SetAnimationComponent(int animationState, float transitionDuration, Blending blendingType, bool isLooping, bool lockAnimation, float playingSpeed, float velocity);

	float GetMaxSpeed();
	float GetAcceleration();
	DirectX::XMVECTOR GetLookDir();
	DirectX::XMVECTOR GetUpDir();
	DirectX::XMVECTOR GetRightDir();
	bool GetIsAming();
	Entity* GetGrabbed();
	Entity* GetBall();
	Ragdoll* GetRagdoll();
	bool isAnimationChanged();	//Compares the current Animation State against the previous frame's Animation State
	float TimeSinceThrow();

	DirectX::XMVECTOR GetAnklePosition(); // position for where the chain is.

private:

};

#endif


Scottrade Login is a US based, private online retail brokerage service company. It was founded in 1980 by Rodger O. Riney, who is also the present CEO of the company. Scottrade consists of 503 offices which are spread all over the United States with its headquarters in Missouri. The online products of Scottrade are; Stocks, Options, Mutual Funds, IRAs, CDs, Fixed Income, Etc. Scottrade has over 4000 employees. And their net revenue is appx $795M.
Scottrade operates through both online and branch offices, to offer their customers; brokerage services, banking services, investment education, award-winning online trading platforms. It also includes; the Scottrade Trading Website, Scottrade ELITE Advanced Trading Platform, Scottrade Streaming Quotes, Scottrade Options First, Scottrade Mobile Application, and Scottrade Mobile Website.
Scottrade also launched their mobile application for all platforms including; Android, iOS, Windows, and Blackberry devices. It was revealed by the Scottrade company itself that the data of 4.6 million customers including their personal information, such as their names, Social Security numbers, email and street addresses, as well as account numbers, were stolen by some hackers. This was a huge setback for the country. Despite that, Scottrade managed to get through that period. Through Scottrade Login at www.scottrade.com users can access their account. Here, you will learn about Scottrade Login procedure.
You can follow the steps below to access your Scottrade online account. Before login you must first create an account, in order to avail their services. You need a device (PC, mobile, tablet etc.) with active internet connection for account login. For more secure Scottrade login change your browsing settings to, private. This would save your data from unauthorized access.
These are some easy steps for Scottrade login. If you still face any problem in login, use the links provided for customer care service and secure login assistance, on the same page.


text:
Q: Best way to use the current URL as a parameter to external API in javascript I would like to know what is the best way fetch a resource from our client's site to our servers with the Fetch API (GET). In order to do so we need to send the current URL since the resource depends on that.
We've come up with two choices so far:

*

*Sending the current URL encoded with encodeURIComponent as part of the query string. Could be also base64 if it is safer. In this case, which is the best function that is PHP compatible for decoding?

*Using the referer header of the HTTP Request. We found out that this works without additional effort but the default value for this is not consistent among browsers due to privacy concerns [1]. We could try to force the referrer Policy to no-referrer-when-downgrade for this particular request but in doing so we wouldn't want to hurt the user's privacy.

Thanks
[1] https://web.dev/referrer-best-practices/

redpajama_set_name: RedPajamaStackExchange


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Knowing how to handle objections from clients begins with anticipating their concerns. Your attitude at the start will directly affect your sales at the end of the day. Feel Felt Found and has been used and proven successful for direct sales to the public.
It's quick and easy to learn, and to put into action.
Great podcast on handling Objections. As you were going through the objections I had my own stories that came to mind of how I overcame all these objections myself or knew someone that has.
Really good podcast with helpful examples!


I moved to Central Portugal in 2007 with 2 sons, James & Daniel.
In 2012 I changed locations to the Silver Coast, and now live in Nadadouro.
Like many other people who have moved to Central Portugal from the UK in recent years we have found it difficult to get information about the things we all need to know. Information about how to register at the Centro de Saude, how does the Via Verde Motorway toll system work, where and when are all the markets on, what date is my local festa, when are the Portuguese National Holidays, How do I get the children into school....and so much more.
So HeyPortugal.com was started, to tell other about the things that we had struggled with ourselves and it just grew. If you live in Portugal you will know how difficult is it to find out the 'latest' information about things, well Hey Portugal intends to get this information for you and publish it for all to read.
I have a background in Quality Management, in a number of different industries, and as a qualified auditor for many years I have a particular knack of getting information out of people.
I have inks with the British Embassy and Consulate and the Central Portugal Tourist Board as well as a number of Town Councils, and so plans to keep the readers as informed as possible about what's going on in Central Portugal and to help make Life in central Portugal and the Silver Coast a bit easier for the Expats here, whether British Expats or other English speakers.
Through Hey Portugal I have already been involved with the British Consulate to sort out problems Expats were experiences with Healthcare and other issues.
I am very keen to provide acurate and current information for Expats in Portugal, driven by the fact that when I arrived it was very difficult to get information. Even now there are other Expat websites that have out-of-date and misleading information about moving to and living in central Portugal and the Silver Coast.
Hey Portugal is The Website for Central Portgual in English.
If you want to contact Wendy then please use the Contact Us page.


text:
U.S. Legal News
New York sues Weinstein Co., Harvey Weinstein over sexual misconduct
By Jessica DiNapoli, Michael Erman
NEW YORK (Reuters) - New York's attorney general sued the Weinstein Company and Harvey Weinstein on Sunday alleging years of sexual harassment and misconduct by the movie producer, in a move that could jeopardize talks on a potential sale of the studio.
Weinstein, co-founder of the Miramax studio, was one of Hollywood's most influential men before more than 70 women accused him of sexual misconduct, including rape. He denies having non-consensual sex with anyone, and his lawyer said many of the latest allegations would turn out to be unmerited.
The civil suit alleges that the company's executives and board repeatedly failed to protect employees from Weinstein, Attorney General Eric Schneiderman said in a statement. The suit also names Weinstein's brother Bob, who co-founded the company.
The studio has been in talks to sell itself to a group of investors led by former Obama administration official Maria Contreras-Sweet, but Schneiderman's lawsuit has put deal negotiations on hold, according to people familiar with the matter.
Schneiderman said he sued the company on Sunday in part because of reports that a sale of the studio could be imminent.
"Any sale of The Weinstein Company must ensure that victims will be compensated, employees will be protected going forward, and that neither perpetrators nor enablers will be unjustly enriched," Schneiderman said.
The state is seeking an unspecified amount of restitution and damages, plus penalties, for harm to victims.
The lawsuit alleges that Weinstein, 65, sexually harassed employees and abused women for years. It accuses Weinstein Company executives, including his brother and co-CEO Bob, of failing to act despite repeatedly being presented with credible evidence of Weinstein's sexual harassment and misconduct.
In a statement, Weinstein's attorney Ben Brafman said a fair investigation by Schneiderman would prove that many of the allegations against his client were without merit.
"While Mr. Weinstein's behavior was not without fault, there certainly was no criminality, and at the end of the inquiry it will be clear that Harvey Weinstein promoted more women to key executive positions than any other industry leader and there was zero discrimination at either Miramax or TWC," Brafman said.
"If the purpose of the inquiry is to encourage reform throughout the film industry, Mr. Weinstein will embrace the investigation. If the purpose however is to scapegoat Mr. Weinstein, he will vigorously defend himself," Brafman said.
Schneiderman said he used his subpoena power in an attempt to get around Non-Disclosure Agreements that Weinstein and the company signed with employees and others in what the attorney general described as an attempt to shield them from scrutiny.
The New York Times first reported in October on multiple allegations of sexual misconduct by Weinstein. Reuters has not been able to independently confirm the allegations.
Since then, similar allegations have been leveled against many powerful men in business, politics and entertainment, and the #MeToo movement has emerged of victims using social media to share their stories of harassment and abuse.
Reporting by Jessica DiNapoli and Michael Erman; Additional reporting by Karen Freifeld; Editing by Daniel Wallis


text:
References of "De Beaufort, Carine 50001475"
Showing results 81 to 100 of 145
The TRIGR Trial: Testing the Potential Link between Weaning Diet and Type 1 Diabetes
Akerblom, H.K.; Knip, M.; Becker, D. et al
in Immunology, Endocrine and Metabolic Agents - Medicinal Chemistry (2007), 7
Study design of the Trial to Reduce IDDM in the Genetically Risk (TRIGR)
Krischer, J.; De Beaufort, Carine
in Pediatric Diabetes (2007), 8
he hypothesis for this study is that weaning to an extensively hydrolyzed infant formula will decrease the incidence of type 1 diabetes (T1D), as it does in all relevant animal models for the disease ... [more ▼]
he hypothesis for this study is that weaning to an extensively hydrolyzed infant formula will decrease the incidence of type 1 diabetes (T1D), as it does in all relevant animal models for the disease. This will be tested in children who carry risk‐associated human leukocyte antigen genotypes and have a first‐degree relative with T1D. The trial will use a double‐blind, prospective, placebo‐controlled intervention protocol, comparing casein hydrolysate with a conventional cow's milk (CM)‐based formula. A secondary aim is to determine relationships between CM antibodies, a measure of CM exposure, and diabetes‐associated autoantibodies. To achieve an 80% power for the detection of a 40% intervention‐induced difference in the development of autoantibodies and subsequent diabetes, the study requires 2032 subjects. A multicenter, international, collaborative effort is necessary to achieve recruitment targets. A collaborative international study group of 78 clinical centers in 15 countries has therefore been assembled for this purpose. [less ▲]
Effect of 2 years of high-dose growth hormone therapy on cognitive and psychological development in short children born small for gestational age
Lagrou, K.; Vanderfacillic, J.; Froidecoeur, C. et al
in European Journal of Endocrinology (2007), 156(2), 195-201
Objective and design: Children born small for gestational age (SGA) are not only at risk for short stature, but also for neurodevelopmental and behavioral problems. In this study, we analyzed the effects ... [more ▼]
Objective and design: Children born small for gestational age (SGA) are not only at risk for short stature, but also for neurodevelopmental and behavioral problems. In this study, we analyzed the effects of high-dose GH therapy on cognitive development and psychosocial functioning in 34 prepubertal (3-8 years) short SGA children, equally randomized into a GH-treated group (TRG) and an untreated group (UTRG). Methods: At start and after 2 years, children underwent standardized tests measuring the intellectual abilities (Wechsler Preschool and Primary Scale of Intelligence-Revised, or Wechsler Intelligence Scale for Children-Revised); their parents completed a standardized questionnaire evaluating psychosocial functioning (Child Behavior Checklist; CBCL). Results: At start, total IQ scores were significantly (P<0.05) lower in the SGA group than in the general population: 32% of the SGA patients had scores below 85. After 2 years, IQ scores remained unchanged in the TRG, but increased significantly (P<0.05) in the UTRG. After exclusion of children with developmental problems, however, no significant changes in IQ scores occurred in the UTRG as well as the TRG. At baseline, 24% (8/34) children had problematic CBCL total problems scores, equally distributed among the two groups; no significant changes in the different subscale scores occurred after 2 years. Conclusion: No beneficial effect of 2 years of GH therapy on cognitive and behavioral profile could be observed in a cohort of rather young short SGA children presenting a variable degree of developmental delay and behavioral problems. Subsequent follow-up could reveal potential long-term effects of GH therapy on development and behavior. © 2007 Society of the European Journal of Endocrinology. [less ▲]
Continuing stability of center differences in pediatric diabetes care: do advances in diabetes treatment improve outcome? The Hvidoere Study Group on Childhood Diabetes
De Beaufort, Carine ; Swift, Peter G. F.; Skinner, Chas T. et al
in Diabetes Care (2007), 30(9), 2245-50
OBJECTIVE: To reevaluate the persistence and stability of previously observed differences between pediatric diabetes centers and to investigate the influence of demography, language communication problems ... [more ▼]
OBJECTIVE: To reevaluate the persistence and stability of previously observed differences between pediatric diabetes centers and to investigate the influence of demography, language communication problems, and changes in insulin regimens on metabolic outcome, hypoglycemia, and ketoacidosis. RESEARCH DESIGN AND METHODS: This was an observational cross-sectional international study in 21 centers, with clinical data obtained from all participants and A1C levels assayed in one central laboratory. All individuals with diabetes aged 11-18 years (49.4% female), with duration of diabetes of at least 1 year, were invited to participate. Fourteen of the centers participated in previous Hvidoere Studies, allowing direct comparison of glycemic control across centers between 1998 and 2005. RESULTS: Mean A1C was 8.2 +/- 1.4%, with substantial variation between centers (mean A1C range 7.4-9.2%; P < 0.001). There were no significant differences between centers in rates of severe hypoglycemia or diabetic ketoacidosis. Language difficulties had a significant negative impact on metabolic outcome (A1C 8.5 +/- 2.0% vs. 8.2 +/- 1.4% for those with language difficulties vs. those without, respectively; P < 0.05). After adjustement for significant confounders of age, sex, duration of diabetes, insulin regimen, insulin dose, BMI, and language difficulties, the center differences persisted, and the effect size for center was not reduced. Relative center ranking since 1998 has remained stable, with no significant change in A1C. CONCLUSIONS: Despite many changes in diabetes management, major differences in metabolic outcome between 21 international pediatric diabetes centers persist. Different application between centers in the implementation of insulin treatment appears to be of more importance and needs further exploration. [less ▲]
Use of insulin pump therapy in the pediatric age-group: consensus statement from the European Society for Paediatric Endocrinology, the Lawson Wilkins Pediatric Endocrine Society, and the International Society for Pediatric and Adolescent Diabetes, endorsed by the American Diabetes Association and the European Association for the Study of Diabetes
Phillip, M.; Battelino, T.; Rodríguez, H. et al
in Diabetes Care (2007), 30(6), 1653
Support for young people with diabetes
De Beaufort, Carine ; Swift, P.
in The BMJ (2006), 333(7558), 55-56
From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation.
Sagen, Jorn V.; Odili, Stella; Bjorkhaug, Lise et al
in Diabetes (2006), 55(6), 1713-22
Glucokinase functions as a glucose sensor in pancreatic beta-cells and regulates hepatic glucose metabolism. A total of 83 probands were referred for a diagnostic screening of mutations in the glucokinase ... [more ▼]
Glucokinase functions as a glucose sensor in pancreatic beta-cells and regulates hepatic glucose metabolism. A total of 83 probands were referred for a diagnostic screening of mutations in the glucokinase (GCK) gene. We found 11 different mutations (V62A, G72R, L146R, A208T, M210K, Y215X, S263P, E339G, R377C, S453L, and IVS5 + 1G>C) in 14 probands. Functional characterization of recombinant glutathionyl S-transferase-G72R glucokinase showed slightly increased activity, whereas S263P and G264S had near-normal activity. The other point mutations were inactivating. S263P showed marked thermal instability, whereas the stability of G72R and G264S differed only slightly from that of wild type. G72R and M210K did not respond to an allosteric glucokinase activator (GKA) or the hepatic glucokinase regulatory protein (GKRP). Mutation analysis of the role of glycine at position 72 by substituting E, F, K, M, S, or Q showed that G is unique since all these mutants had very low or no activity and were refractory to GKRP and GKA. Structural analysis provided plausible explanations for the drug resistance of G72R and M210K. Our study provides further evidence that protein instability in combination with loss of control by a putative endogenous activator and GKRP could be involved in the development of hyperglycemia in maturity-onset diabetes of the young, type 2. Furthermore, based on data obtained on G264S, we propose that other and still unknown mechanisms participate in the regulation of glucokinase. [less ▲]
Impact of IDDM2 on disease pathogenesis and progression in children with newly diagnosed type 1 diabetes: Reduced insulin antibody titres and preserved beta cell function
Nielsen, L. B.; Mortensen, H. B.; Chiarelli, F. et al
in Diabetologia (2006), 49(1), 71-74
Aims/hypothesis: The insulin-dependent diabetes mellitus 2 gene (IDDM2) is a type 1 diabetes susceptibility locus contributed to by the variable number of tandem repeats (VNTR) upstream of the insulin ... [more ▼]
Aims/hypothesis: The insulin-dependent diabetes mellitus 2 gene (IDDM2) is a type 1 diabetes susceptibility locus contributed to by the variable number of tandem repeats (VNTR) upstream of the insulin gene (INS). We investigated the association between INS VNTR class III alleles (-23HphIA/T) and both insulin antibody presentation and residual beta cell function during the first year after diagnosis in 257 children with type 1 diabetes. Materials and methods: To estimate C-peptide levels and autoantibody presentation, patients underwent a meal-stimulated C-peptide test 1, 6, and 12 months after diagnosis. The insulin -23HphIA/T variant was used as a marker of class III alleles and genotyped by PCR-RFLP. Results: The insulin antibody titres at 1 and 6 months were significantly lower in the class III/III and class I/III genotype groups than in the class I/I genotype group (p = 0.01). Class III alleles were also associated with residual beta cell function 12 months after diagnosis and independently of age, sex, BMI, insulin antibody titres, and HLA-risk genotype group (p = 0.03). The C-peptide level was twice as high among class III/III genotypes as in class I/I and class I/III genotypes (319 vs 131 and 166 pmol/l, p=0.01). Furthermore, the class III/III genotype had a 1.1% reduction in HbA1c after adjustment for insulin dose (p = 0.04). Conclusions/interpretation: These findings suggest a direct connection in vivo between INS VNTR class III alleles, a decreased humoral immune response to insulin, and preservation of beta cell function in recent-onset type 1 diabetes. © Springer-Verlag 2005. [less ▲]
Identification of novel and recurrent glucokinase mutations in Belgian and Luxembourg maturity onset diabetes of the young patients [1]
Vits, L.; Beckers, D.; Craen, M. et al
in Clinical Genetics (2006), 70(4), 355-359
Incidence and trends of Childhood Type 1 diabetes worldwide 1990-1999
De Beaufort, Carine
in Diabetic Medicine: A Journal of the British Diabetic Association (2006), 23(8), 857-866
AIM: To examine incidence and trends of Type 1 diabetes worldwide for the period 1990-1999. METHODS: The incidence of Type 1 diabetes (per 100 000/year) was analysed in children aged <or= 14 years from ... [more ▼]
AIM: To examine incidence and trends of Type 1 diabetes worldwide for the period 1990-1999. METHODS: The incidence of Type 1 diabetes (per 100 000/year) was analysed in children aged <or= 14 years from 114 populations in 112 centres in 57 countries. Trends in the incidence of Type 1 diabetes were analysed by fitting Poisson regression models to the dataset. RESULTS: A total of 43,013 cases were diagnosed in the study populations of 84 million children. The age-adjusted incidence of Type 1 diabetes among 112 centres (114 populations) varied from 0.1 per 100,000/year in China and Venezuela to 40.9 per 100,000/year in Finland. The average annual increase in incidence calculated from 103 centres was 2.8% (95% CI 2.4-3.2%). During the years 1990-1994, this increase was 2.4% (95% CI 1.3-3.4%) and during the second study period of 1995-1999 it was slightly higher at 3.4% (95% CI 2.7-4.3%). The trends estimated for continents showed statistically significant increases all over the world (4.0% in Asia, 3.2% in Europe and 5.3% in North America), except in Central America and the West Indies where the trend was a decrease of 3.6%. Only among the European populations did the trend in incidence diminish with age. CONCLUSIONS: The rising incidence of Type 1 diabetes globally suggests the need for continuous monitoring of incidence by using standardized methods in order to plan or assess prevention strategies. [less ▲]
Evolution du traitement médicamenteux du diabète au Luxembourg.
Perquin, M.; Keipes, M.; Wirion, R. et al
in Bulletin de la Société des Sciences Médicales du Grand-Duché de Luxembourg (2006), (1), 29-35
OBJECTIVES: The aims of the study were to estimate the prevalence of diabetes in Luxembourg in 2002, to compare it to the prevalence reported in 1991 and to evaluate if prescription attitudes have changed ... [more ▼]
OBJECTIVES: The aims of the study were to estimate the prevalence of diabetes in Luxembourg in 2002, to compare it to the prevalence reported in 1991 and to evaluate if prescription attitudes have changed since 1991. METHODS: The prevalence of diabetes was estimated using the drug sales data. The key parameters, total amount of antidiabetic drugs sold in one year and the average daily dose or Prescribed Daily Dose (PDD), have been obtained from the National Social Security Organization and by a standardized questionnaire sent to all general practitioners and all internists and endocrinologists of the country. RESULTS: The PDD was calculated on 2,402 questionnaires on individual diabetic patients. By this mean, the proportion of patients only treated with appropriate diet could also be obtained. Compared to 1991, the total amount of antidiabetic drugs showed a four-fold increase in biguanides tablet prescriptions. A high percentage of combined treatments was found. The prevalence of diabetes in Luxembourg was found to be 3.05% of the total population. CONCLUSIONS: Compared to the status in 1991, prevalence of diabetes increased by 63%, which seems mainly due to type 2 diabetic patients as orally-treated diabetic patients almost doubled (2.11% vs 1.16%). A substantial change in prescriptions for diabetes has occurred, suggesting a positive influence of studies like the United Kingdom Prospective Diabetes Study (UKPDS). [less ▲]
Acute pancreatitis after growth hormone treatment: disease or treatment linked?
De Beaufort, Carine ; Beck, P.; Seligmann, R. et al
in European Journal of Pediatrics (2006), 12
A cross-sectional international survey of continuous subcutaneous insulin infusion (CSII) in 377 children and adolescents with type 1 diabetes mellitus from 10 countries
Danne, T.; Battelino, T.; Kordonouri, O. et al
OBJECTIVE: To document current practices using continuous subcutaneous insulin infusion (CSII) by downloading electronically the 90-d pump data held within the pump memory and relating that to clinical ... [more ▼]
OBJECTIVE: To document current practices using continuous subcutaneous insulin infusion (CSII) by downloading electronically the 90-d pump data held within the pump memory and relating that to clinical data from children and adolescents in different pediatric diabetes centers from Europe and Israel. METHODS: Data of patients (1-18 yr) treated with CSII in 23 centers from nine European countries and Israel were recorded with the encapture software (PEC International, Frankfurt, Germany). The number of patients who participated was 377 (48% female; mean diabetes duration +/- SD: 6.8 +/- 3.7 yr; age: 12.9 +/- 3.8 yr, preschool n = 33; prepubertal n = 95; adolescent n = 249; CSII duration: 1.6 +/- 1.2 yr; local HbA1c: 8.1 +/- 1.2%). RESULTS: The total insulin dose was lower than previously reported for injection therapy (0.79 +/- 0.20 U/kg/d). Covariance coefficient of daily total insulin was high in all age groups (adolescents 19 +/- 9%, prepubertal 18 +/- 8 and preschool 17 +/- 8). The distribution of basal insulin infusion rates over 24 hr (48 +/- 12% of total dose) varied significantly between centers and age groups. The number of boluses per day (7 +/- 3) was not significantly different between the age groups (average daily bolus amount: 0.42 +/- 0.16 U/kg). The rate of severe hypoglycemia (coma/convulsions) was 12.4 episodes per 100 patient-years and the number of diabetes-related hospital days was 124 per 100 patient-years. DISCUSSION: Pediatric CSII patients show a high variability in their insulin therapy. This relates both to age-dependent differences in the distribution of basal insulin as to the age-independent day-to-day variation in prandial insulin. [less ▲]
Changes in diabetes prevalence and treatment in the last ten years in Luxembourg. A lesson from the United Kingdom prospective diabetes study?
Perquin, M.; Michel, G. H.; De Beaufort, Carine et al
in Diabetes and Metabolism (2005), 31(5), 499-502
Objectives: The aims of the study were to estimate the prevalence of diabetes in Luxembourg in 2002, to compare it to the prevalence reported in 1991 and to evaluate if prescription attitudes have changed since 1991. Methods: The prevalence of diabetes was estimated using the drug sales data. The key parameters, total amount of antidiabetic drugs sold in one year and the average daily dose or Prescribed Daily Dose (PDD), have been obtained from the National Social Security Organization and by a standardized questionnaire sent to all general practitioners and all internists and endocrinologists of the country. Results: The PDD was calculated on 2, 402 questionnaires on individual diabetic patients. By this means, the proportion of patients only treated with appropriate diet could also be obtained. Compared to 1991, the total amount of antidiabetic drugs showed a four-fold increase in metformine tablet prescriptions. A high percentage of combined treatments was found. The prevalence of diabetes in Luxembourg was found to be 3.05% of the total population. Conclusions: Compared to the status in 1991, prevalence of diabetes increased by 63%, which seems mainly due to type 2 diabetic patients as orally-treated diabetic patients almost doubled (2.11% vs 1.16%). A substantial change in prescriptions for diabetes has occurred, suggesting a positive influence of studies like the United Kingdom Prospective Diabetes Study (UKPDS). © 2005 Masson, all rights reserved. [less ▲]
European Union diabetes indicators: Fact or fiction?
De Beaufort, Carine ; Reunanen, A.; Raleigh, V. et al
in European Journal of Public Health (2003), 13(3 SUPPL.), 51-54
Diabetes mellitus is one of the major causes of morbidity and mortality in EU/EFTA countries. Monitoring risk factors for diabetes and its complications will offer the possibility to evaluate the ... [more ▼]
Diabetes mellitus is one of the major causes of morbidity and mortality in EU/EFTA countries. Monitoring risk factors for diabetes and its complications will offer the possibility to evaluate the development in time as well as the influence of possible interventions. In this investigation a list with core and secondary indicators is proposed. Availability of these indicators and their data sources is discussed. An important variability of data sources is used in EU/EFTA countries, interfering with the comparability of the outcome. Further harmonisation as well as continuous evaluation of data sources will be necessary to provide reliable tools to monitor diabetes mellitus and its outcome on a routine basis. [less ▲]
Differential binding of IgG and IgA antibodies to antigenic determinants of bovine serum albumin
Hilger, C.; Grigioni, F.; De Beaufort, Carine et al
in Clinical and Experimental Immunology (2001), 123(3), 387-394
The aim of this study was to investigate the recognition pattern of bovine serum albumin (BSA), a major dietary protein by serum IgG and IgA antibodies. Anti-BSA IgG and IgA antibodies were measured by ... [more ▼]
The aim of this study was to investigate the recognition pattern of bovine serum albumin (BSA), a major dietary protein by serum IgG and IgA antibodies. Anti-BSA IgG and IgA antibodies were measured by ELISA technique in 3 different cohorts: 578 unselected persons, 84 new-onset insulin-dependent diabetes mellitus (IDDM) patients and 103 atopic persons. In order to characterize the recognition pattern of the different BSA domains, recombinant BSA and recombinant fragments covering the 3 BSA domains were produced. BSA digestion was monitored in simulated gastric fluid experiments by means of domain specific monoclonal antibodies. IgG and IgA antibody titres to native BSA were highest in DDM patients. The three major BSA domains were equally well recognized by IgG antibodies of the three cohorts. Interestingly all three study groups showed a dissociation of their IgG and IgA antibody response to the first BSA domain. The ratio of IgG to IgA antibodies recognizing this domain was 93%/42% in controls, 92%/37% in IDDM patients and 80%/47% in atopic persons. In simulated gastric fluid experiments, the first BSA domain was the first to become undetectable to specific monoclonal antibodies during digestion. In conclusion humoral IgG and IgA antibodies recognize the major BSA domains with different frequencies. The N-terminal domain of BSA, the first to be degraded during simulated gastric digestion is less well recognized by IgA antibodies. This suggests that early digestion is negatively correlated to the IgA antibody response and that the IgA response associated to the gut associated lymphoid tissue (GALT) and the systemic IgG antibody responses are independent. [less ▲]
Correlations between the incidence of childhood onset type 1 diabetes in Europe and HLA genotypes
Ronningen, K.S.; Keiding, N.; Green, A. et al
Sexual precocity after immigration from developing countries to Belgium: Evidence of previous exposure to organochlorine pesticides
Krstevska-Konstantinova, M.; Charlier, C.; Craen, M. et al
in Human Reproduction (2001), 16(103), 1020-1026
In a retrospective auxological study of 145 patients seen in Belgium during a 9-year period for treatment of precocious puberty, 28% appeared to be foreign children (39 girls, one boy) who immigrated 4 to ... [more ▼]
In a retrospective auxological study of 145 patients seen in Belgium during a 9-year period for treatment of precocious puberty, 28% appeared to be foreign children (39 girls, one boy) who immigrated 4 to 5 years earlier from 22 developing countries, without any link to a particular ethnic or country background. The patients were either adopted (n = 28) or non-adopted (n = 12), the latter having normal weight and height at immigration and starting early puberty without evidence of earlier deprivation. This led to the hypothesis that the mechanism of precocious puberty might involve previous exposure to oestrogenic endocrine disrupters. A toxicological plasma screening for eight pesticides detected p,p′-DDE, which is derived from the organochlorine pesticide DDT. Median p,p′-DDE concentrations were respectively 1.20 and 1.04 ng/ml in foreign adopted (n = 15) and non-adopted (n = 11) girls with precocious puberty, while 13 out of 15 Belgian native girls with idiopathic or organic precocious puberty showed undetectable concentrations (<0.1 ng/ml). A possible relationship between transient exposure to endocrine disrupters and sexual precocity is suggested, and deserves further studies in immigrant children with non-advanced puberty. [less ▲]
Seasonality of birth in patients with childhood type 1 diabetes in nineteen European regions
McKinney, P.A.; De Beaufort, Carine
AIMS/HYPOTHESIS: Differences in seasonality of birth patterns between the general population and the group who develop Type I (insulin-dependent) diabetes mellitus indicate that environmental factors ... [more ▼]
AIMS/HYPOTHESIS: Differences in seasonality of birth patterns between the general population and the group who develop Type I (insulin-dependent) diabetes mellitus indicate that environmental factors operating around the antenatal and perinatal period could be important. We investigated whether the same unsual patterns in seasonality of birth observed in children with Type I diabetes in Great Britain could also be found in other European populations. METHODS: Population-based incidence cohorts of children diagnosed with Type I diabetes under 15 years of age from 1989 onwards were analysed. Previously reported data sets from Great Britain were also included together with data on children diagnosed over an additional 5 year period (1988-1992). To assess the role of seasonality in diabetes, we used the method of Walter and Elwood to examine monthly birth figures for each country or region. RESULTS: Outside of Great Britain, no seasonality of birth was seen for any single or combination of European countries. Significant sinusoidal patterns were observed in Scotland, Yorkshire and Leicester, although the peak for Leicester appeared around autumn rather than spring. There was little evidence that sex or age at diagnosis played a part in differences in seasonal patterns, either overall or for any individual country. CONCLUSIONS/INTERPRETATION: We found no uniform seasonal pattern of birth in childhood diabetes patients across European populations, either overall or according to sex and age. This study provides no consistent evidence that environmental factors, which vary from season to season, have any influence on the fetal or neonatal life to determine the onset of Type I diabetes. However, a study of seasonality that takes into account possible changes both over time and over geographical areas could provide more insights. [less ▲]
Geographical variation of presentation at diagnosis of type 1 diabetes in children: the EURODIAB Study
Levy-Marchal, C.; Patterson, C.C.; Green, A. et al
We aimed to describe the frequency and degree of diabetic ketoacidosis in children across Europe at the time of diagnosis of Type I (insulin-dependent) diabetes mellitus and to determine if factors such ... [more ▼]
We aimed to describe the frequency and degree of diabetic ketoacidosis in children across Europe at the time of diagnosis of Type I (insulin-dependent) diabetes mellitus and to determine if factors such as age and geographical region contribute to the risk of diabetic ketoacidosis. METHODS: The study was part of the EURODIAB project. A total of 24 centres, covering a population at risk of more than 15 million children below 15 years of age, recruited 1,260 children at the time of clinical diagnosis. RESULTS: Polyuria, by far the most frequent symptom, was observed in 96% of the children. In only 25% of the children was the duration of symptoms less than 2 weeks and this proportion was larger in the under 5 year age-group (37 vs 22%; p < 0. 001). Of the 11 centres that recorded diabetic ketoacidosis status, the overall proportion with diabetic ketoacidosis (pH < 7.3) was 40% (95%-CI: 36-44%) in at least 90 % of cases. After stratification by centre, the odds ratio for diabetic ketoacidosis in the under 5 age-group was 1.02 (95%-CI:0.69-1.49) relative to the older children. There was significant variation between the 11 centres in the frequency of diabetic ketoacidosis which ranged from 26 to 67% (p = 0.002). An inverse correlation between the frequency of diabetic ketoacidosis and the background incidence rate was found in these centres (Spearman's rank correlation, rs = -0.715;p = 0.012). CONCLUSION/INTERPRETATION: Rising standards of medical information and greater awareness concurrent with an overall increase in incidence could have resulted in changes in the clinical presentation at onset of Type I childhood diabetes in Europe. [less ▲]


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Teton Trekker shared this really easy Pot Luck Elk Roast – I bet you could use beef too. Delicious!
Next up – Comfort Springs made it into the featured list again – tied for number one…Low Country Shrimp & Grits.
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Now we have some ideas for dinner!
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Spelman already accepts transgender women.
Morehouse is an all-male college. But what happens if you are male and while attending Morehouse—having paid thousands of dollars in tuition—you realize that you are transgender? Should the institution be allowed to kick you out? What if you are a transgender man, should you not be allowed to attend Morehouse? Is Morehouse only for a cisgender person (someone who identifies with the gender they are assigned at birth)? Morehouse is grappling with these questions now.
Yesterday, Morehouse sent out a six-question survey to alumni that read, "We at Morehouse College respect and support every individual's right to self-identification as they pursue their education at our world-class institution. As an all men's college, we know that the identity discussion can be a very complex topic to consider. But Morehouse has a history of leading the nation in difficult discussions that have paved the way for positive change and social justice for all Americans. Morehouse is considering the establishment of a Transgender Policy to set protocol for admissions and student life. This issue is one that we as a community must engage in with sensitivity and respect for one another without ever losing focus on the mission of our College.
1. Morehouse should admit students who self identify as men, regardless of their gender at birth.
2. Morehouse shouldn't admit students who self identify as women, regardless of their gender at birth.
3. If a Morehouse student transitions from a man to a woman while at the College, the student should be allowed to continue their education and graduate from the College.
4. Does a policy that expels a student who transitions from a man to a woman align with the mission of the College?
5. Does a policy that allows a woman to graduate a line with the mission of the College.


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Of the three, our preschooler had the hardest time with her end of school year... she loved her preschool teachers and class so much that she did not want it to be done. She has grown so much and is already looking forward to kindergarten to start.
Our kindergartner worked so hard this year and we are so proud of him. He is a bit nervous for first grade next year but already found out once of his friends will be in his class so that helps a bit. He is very ready for summer fun!
Our second grader had a great year of school, really enjoyed his teacher and made some new friends. He's excited about his teacher for next year and two of his buddies are in his class. He is very ready for more lego time and more free time this summer.
As is tradition with our picture sessions, there were absolutely some crazy shots to share as well. Their silly mood was contagious and filled our morning with smiles.
We are so thankful that they each had wonderful teachers who poured into them all year. Each kid grew and learned and rose to new challenges. We are so proud. I can barely believe we'll have a third grader, first grader and kindergartner in the fall.
Let the summer fun begin on the gravelly road!


text:
Q: How to supress a subreport if it has no data? The solution below was posted by user Brian for how to suppress empty subreport in SSRS2008. The answer is to place the subreport into a rectangle. Then set the visibility of the rectangle to something like this:
=IIF(First(Fields![SOMEFEILD].Value, "[SOMEDATASET]") IS NOTHING, TRUE, FALSE)

I tried the recommended expression but it didn't work. The expression doesn't make sense because I didn't think a rectangle has fields that make up a dataset instead it's an object. So how would I reference a field value in the rectangle like in the expression sample? For me, what would [SOMEDATASET] be?
Note: I placed the subreport into a rectangle. The subreport has a dataset called DataSet1 with three fields in it.

A: The dataset in your main report should query the same data as the one in the subreport. To keep things DRY you could use a View or Stored Procedure as a basis for both reports. To keep things nice performance-wise your main report's DataSet could get away with something like:
SELECT COUNT(*) FROM vw_SomeViewForSubreport

Then use this in the subreport:
SELECT field1, field2, field3 FROM vw_SomeViewForSubreport


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text:
Lískovice  est une commune du district de Jičín, dans la région de Hradec Králové, en Tchéquie. Sa population s'élevait à  habitants en 2022.

Géographie
Lískovice se trouve à  au sud-ouest de Hořice, à  au sud-est de Jičín, à  au nord-ouest de Hradec Králové et à  à l'est-nord-est de Prague.

La commune est limitée par Ostroměř au nord, par Dobrá Voda u Hořic et Bašnice à l'est, par Sukorady au sud-ouest, par Myštěves et Šaplava au sud, et par Ohnišťany à l'ouest et par Chomutice au nord-ouest.

Histoire
La première mention écrite de la localité date de 1295.

Administration
La commune se compose de deux sections :
 Lískovice
 Tereziny Dary

Transports
Par la route, Holín se trouve à  de Hořice, à  de Jičín, à  de Hradec Králové et à  de Prague.

Notes et références

Commune dans le district de Jičín

redpajama_set_name: RedPajamaWikipedia


text:
Cultural Resource of Diplomacy (Russian-Polish Experience)
Natalia Goncharova, Art Historian and Curator, National Center for Contemporary Art, Moscow, Russia
My presentation refers to the Cross-Cultural Year of Poland and Russia which was cancelled in July 2014. Cultural diplomacy, according to a well-known definition of American researcher Milton Cummings is "the exchange of ideas, information, art and other aspects of culture among nations and their peoples in order to foster mutual understandings"(1). On July 23, Polish Press Agency (PAP) reported the decision of Polish government, announced by its spokesperson Malgorzata Kidawa-Blonska, to cancel the pre-planned 2015 Polish Year in Russia. The decision was due to the ongoing situation in Ukraine and the shooting down of the Malaysia Airlines flight. Foreign minister Radoslaw Sikorski and culture minister Malgorzata Omilanowska unequivocally came to the conclusion that in current political situation it would be impossible to follow through with the organization of the Polish Year in Russia. Kidawa-Blonska said that "culture should bring together spectators and artists, there should be a good atmosphere, and it must build unity. However, current events do not allow for this". Culture once again became a hostage to the political situation. The decision was announced when I was in Poland negotiating a series of Polish art exhibitions to be organized in Russia. It is hard to convey the feelings I experienced that time. In complete disarray, I was calling the artist Jaroslaw Kozlowski: the statement was a blow to all our plans, almost finalized at that moment. Just over two weeks the Adam Mickiewicz Foundation was going to announce and provide financial support for the projects. Obviously, we had to postpone all the plans and cancel some of them. National Center for Contemporary Art, where I worked, had long-standing and strong relations with Poland, our plans for 2015 were extensive. Those included solo exhibitions of Katarzyna Kozyra and Jozef Robakowski in Moscow and a series of events, evoking great interest in Polish culture. Within a month, we had a flurry of refusals, the projects were foiled. The issue was much debated in the Polish media, and the government's spokesperson stressed that many Polish artists said forcefully that the event had to be postponed or cancelled. But opinions were far from being uniformed, the New Poland magazine presented positions of two prominent figures of Polish culture. So, film director Krzysztof Zanussi made the following assessment of the government's decision, "I know that the public opinion has been stirred by the latest events. And the government should reckon with it. However, with regard to our long-term relations with Russia, I regret that this year has been cancelled because it could have been an opportunity for a dialogue which is now interrupting on every front. […] Russia broke away from the world community. I believe that culture people should maintain contacts […]. Our situation predisposes us to be the first in Western Europe to pursue dialogue with the Russians"(2). In September, I took part in a round table discussion organized by Stefan Batory Foundation in Warsaw where there broke a serious debate on the issue of culture year's cancellation. And I tried to convey my idea that the exchange between our cultures should not be stopped, government officials had their agenda but it would be very unfortunate if the artists became like them. We should not erect, with our own hands, a wall between our cultures and so, between our countries. People from the arts and culture field of different countries belong to a single community, a Single Territory of Arts. Art should not directly fall under the policy area, should not become an instrument of manipulation. But it does not negate the art's involvement in urgent contemporary processes. Closed borders and cancelled projects just deepen misunderstanding between us, and narrow cultural horizons.
(1) Cummings Milton C.Jr. Cultural Diplomacy and the United States Government. Washington DC: Center for Arts and Culture, 2003 P. 1'
(2) Elżbieta Savitskaya Cultural Chronicle. New Poland Magazine 2014. № 9. Online version: http://novpol.org/ru/rJLNuzwjb/KULTURNAYa-HRONIKA
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