Ever feel disconnected or unaligned with some of your business goals?
Have you considered whether your goals stem from a place of ego vs. Spirit and desire?
Everyone I've ever met in my coaching practice desires to do good work that positively influences the world.
However, unconsciously, sometimes our goals are driven by our ego.
Let's dive into how to discern between ego-driven goals and desire-led goals!
Changes constantly through time, trends, seasons, and other outside circumstances.
The similarity in ego-driven goals is that we place our power outside of ourselves – whether in a false identity or expectation we've created in our minds or giving our power away to others.
Deeply personal and individual – your desire driven goals will look completely different to someone else's desire driven goals!
Persistent – these goals tend to stick and stay there even if we try to talk ourselves out of it, convince ourselves we don't need it etc.
The most powerful thing you can do as a business owner is get back in your own power when it comes to your business goals and practicing discernment when it comes to your goal setting practice.
When I first started out, I remember this HUGE desire to start coaching clients on a 1:1 basis (in a high end package and large container).
I shared it with my coach at the time – who shared it was better for me to focus on other projects like smaller courses and products – as high-end private clients tend to come after you've been in business or out in this online world for awhile!
But that nagging desire was that and wouldn't go away!
So I decided to do it my own way and opened up my calendar for 2 private coaching clients at $3,500 packages.
I booked one beautiful client who I absolutely adored working with.
The next signed up to work with me within the next 30 days.
I was ecstatic that I finally was doing what I knew I was meant for – I absolutely loved what I had created in my business.
On the other hand, I also recall chasing those external things I thought I wanted.
I kept travelling even though I knew I desired to start nesting at home.
I over-invested in programs and courses even though I knew it was time to look for different (more aligned) mentor.
I said 'Yes' when I knew it was time for me to lovingly say 'No'.
This led to burning out 2 years ago, finding myself in an externally successful business that didn't feel aligned internally.
It took lots of deep dives, journalling sessions and inquiry – and today I'm so happy to share that this experience has taught me how to discern beautifully between goals that nourish me and those that don't.
When we choose desire driven goals – it doesn't mean life is a piece of cake and a walk in the park. There's still challenges that we may face, however when we are led by Desire there is also a lot more ease and grace in our formula.
I'm holding a FREE workshop on Money & Income Goal Setting and I'd love for you to join me.
We'll be going through each of your goals and ensuring they truly align with what you truly desire – and you'll walk away with the important skill of discernment.
We'll also be setting goals together that are based in Spirit and Desire (vs. ego), so that your business goals feel authentic, inspired, and easeful!
I'll also share a process on how you can let go of those ego-driven goals (that aren't grounded in reality, gets you stuck in spinning and so on) so that you can step back into 100% of your own power when it comes to you and your business!
When we are in this space we easily create and experience our goals – whether it's related to our offerings, clients, sales, income or the decisions we choose to make with our time, money and other resources.


Make the sweet jamaica tea or water (recipe below).
Preheat oven to 350 degrees and place racks in the top and bottom third of the oven. Line 2 baking sheets with parchment paper and set aside.
In a medium bowl, combine the flour, baking powder, baking soda, cocoa powder and salt. Set aside.
In a bain marie, or in a heat-proof bowl set on a pot with simmering water over medium-low heat, melt the chocolate along with the butter, until completely melted and smooth. Stir with a spatula a few times as it melts. Make sure not to overheat it, and stop once it is all melted. Set aside.
In the bowl of a standing mixer, using the whisk attachment, whisk the whole eggs and egg white along with the sugar on medium high speed until frothy, about 2 to 3 minutes. Incorporate the melted chocolate and butter mixture as well as the vanilla extract and whisk until completely combined.
Remove the bowl from the stand and add the flour mixture. Use a rubber spatula to stir and fold until completely combined. Fold in the chopped rehydrated hibiscus flowers. Cover the bowl with plastic wrap and chill the batter in the refrigerator for 20 to 30 minutes.
Using a tablespoon or 2-inch scoop, place the batter in heaping tablespoons onto prepared baking sheets, about 2 inches apart. Bake for 12 to 14 minutes, cool on sheet pans for about 5 minutes and then transfer to cooling racks.
In a medium saucepan, bring water and honey to a boil. Stir in dried hibiscus flowers, stir and cook at a simmer for about 15 minutes, until flowers are completely rehydrated and soft.
Strain flowers, reserving liquid for tea, and finely chop. Set aside.
The cookies are so delicious, they were a HIT with everyone at the baby shower 😋. I have even had people ask me to bake some more for them. Thank you for sharing your great ideas, look forward to trying other recipes.
Awesome! So glad to hear that Sarah.
I'm making these for a baby shower and would like to check the oven temp. Is the temp 350 degrees (Fahrenheit) with fan? I would be cooking them at 180 degrees Celsius or 160 with fan. What do you recommend?
Made these to take for a picnic dinner at an outdoor concert, they were amazing, people in our group were talking them up to friends as they walked by, and we went through the entire batch (there were only 4 of us, so I am hoping we gave a lot of the cookies to passersby!) Thanks so much, for this recipe.
What a fantastic story Chris! Thank you so much for sharing.
Patti, So is the 1/2 flour and 1 1/4 cup sugar proportions stated in the recipe correct, or should they be changed? I often use less sugar than called for, but am mostly worried about the flour measurement. Want to make these for Christmas.
I am so happy it worked out for you! Happy Thanksgiving, Sonia!
Hi Sonia. What are the correct proportions? My cookies failed miserably. Did you use parchment paper without grease? Mine stuck to paper but I don't think the baking time was enough either.
I found the dried flor de jamaica at my local H-mart asian store. First time I have seen them there. They do stock a lot of Latino food items, but will often get an item in stock, and then it disappears, so grab it while you can.
You can also find "hisbiscus" tea at many Hispanic and African food store!
Followup to my previous entry. I have found the hibuscus tea now in two retail stores. Smart and Final and Food for Less. However, I am expremely happy with the product I have been bying from a supplier on Amazon-Frontier Natural Foods Co-op. Product is consistent, well packed . I also found Ceylon cinnamon sticks through them. Think I will just stay with a good thing.
Me too— I buy the Frontier CoOp as well. Excellent, consistent product. I make the tea all the time. Don.t be afraid to adjust the tea ingredient amounts to your own liking. Sometimes I add less hibiscus and add a couple tea bags of Constant Comment Black and Pecot tea. I make the cookies once in a while. I do stick to the original recipe though.


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Don't take our word for it, here are some kind words from a happy client!
…….. just a quick note to say thank you for your wonderful meditation sessions, I'm so glad I stumbled across your website and made the effort to come. I have been wanting to do something like this for months, if not years, but have never found the time, as usually these types of class are too long. But this half hour session you do is perfect, it is enough time to calm my very busy mind and I feel like I have given myself a wonderful treat, without it eating into my day. I love the way you get us to put our thoughts to one side at the beginning of the session so we can focus on the relaxation. And the setting is so perfect and beautiful. I love it. I want to come every week forever!
For people who are not sure what meditation/mindfulness is all about, this is the absolute perfect way to start as you explain everything so clearly and easily.


Pete Petro, who received his Bachelor of Science in Business Administration degree from Samford University on May 12, continues to be an inspiration to all who know him.
Petro has suffered from Duchenne muscular dystrophy since age 5, but that didn't stop him from completing his Samford degree and graduating with honors.
Birmingham's Over the Mountain Journal recently featured Petro in an inspiring story by reporter Emily Williams.


Blackjack is now widely known as one of the casino games that give players the best odds of winning. Part of the fun is knowing that your choices as a player will affect the final outcome, making it a game of skill as well as chance. If you play your hand perfectly, in a casino with the right rules, you can reduce the house edge to as little as 0.8%. Compare that to casino games with some of the worst odds, like certain Keno games where the house has an edge as high as 25%, and Blackjack comes out as the winner's game of choice. But how do we know this, and what exactly does it mean to play your hand perfectly? Well, we have a mathematician named Edward Thorp to thank.
The first member of the Blackjack Hall of Fame, Edward Thorp is the man who pioneered the concept of a basic blackjack strategy. In his 1962 book "Beat the Dealer", now famous as the bible that gave birth to card counting, he explored the maths behind Blackjack and produced a table of moves that gave players the best odds possible. By telling you when to hit, stand, double or split by comparing your hand to the dealer's up card, Thorp's table gives you the best chance of long-term success.
Thorp also discovered that by keeping track of the cards in-play and betting when the odds were in favour of the player, you could actually gain an edge over the house. This is the difference between a basic blackjack strategy and card counting. Thorp put his theories into practice and won thousands at casinos, earning himself an unhealthy reputation in the process. His strategy was so effective that card counting was eventually outlawed in most casinos, and its practitioners blacklisted.
As unwelcome as card counting is, however, many casinos now actually encourage players to learn about and use Thorp's basic strategy. If you ask at your local casino they may even provide a basic strategy chart for you to follow. Thorp's original table is as effective today as it was in 1962, and by following his simple instructions you can convert your Blackjack game from random chance into a specialist art form. Indeed, this basic strategy solidifies Blackjack's reputation as a casino 'skill game', where a player's own actions can adjust how well they perform in the game (similar to poker).
Card counting is impossible at an online casino, where every hand is a new shuffle, but Thorp's basic blackjack strategy is based on individual hand odds, so even online it's a sure way to improve your Blackjack game. You can practise in the comfort of your own home at online sites such as partycasino, with live dealer options making it even more like you're playing in a real venue. The speed of online games will help you to quickly learn the moves, and by rapidly getting through a number of hands you're sure to see the results.


01-04-1974 is the date when the Ladygate Lane Medical Practice was set up. 22 Ladygate Lane at Ruislip, HA4 7QU (postcode) is the exact address where it is located. It is a marvelous area in an awesome city, in a historic country. This association identification code is E86605. HLHG, national grouping and commissioner numbers of this institution are like that: Q71, Y56, 08G. You can reach them by calling the following number: 01895 632741.


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People who live with a Well Manager® or Herculan Constaboost Static Storage System™. They have volunteered these comments and authorized WMS to use them to advertise our products.
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This includes specialized water well management systems that guarantee more water, volume and pressure from any well or community water system. We also offer a line of Reid pressure boosters that are quiet, powerful and compact for buildings connected to a municipal or community water supply. No matter how little the yield or inadequate the pressure, we have a solution that can deliver the water you need and performance you expect!


text:
using System.Data;
using System.Data.Common;

namespace Utilitron.Data
{
    /// <summary>
    ///     Defines configuration necessary for any database context.
    /// </summary>
    public interface IRepositoryConfiguration
    {
        /// <summary>
        ///     The connection string for the database.
        /// </summary>
        string RepositoryConnectionString { get; }

        /// <summary>
        ///     The default amount of time (in seconds) that a database command will run.
        /// </summary>
        int DefaultCommandTimeoutSeconds { get; }

        /// <summary>
        ///     The default isolation level of each transaction.
        /// </summary>
        IsolationLevel TransactionIsolationLevel { get; }
    }
}

redpajama_set_name: RedPajamaGithub


To obtain a position in a nursery environment with an interest in plant propagation to fulfill the growing needs of the green industry.
- Internship with focus on cataloging the Horticulture Department's tropical and indoor plants including preparation of fertilization and maintenance guide.
- Assist Ohio State professors, doctorate candidates, and master's students in the requirements of their research. - Regular program of greenhouse care and maintenance.
- Supervised commercial landscape contracts in Ohio and Kentucky.
- Ordered plant material to fulfill contract specifications.
- Designed retail displays and generated retail sales.
- Maintained field plant material through pruning, scheduled fertilization and pest control.
- Served on machine dig crew in both fall and spring harvesting seasons.
- Garden center maintenance of wholesale and retail container and balled and burlaped material.
- Sales in both Retail and Wholesale Departments.
- Courses include Plant Propagtion, Woody and Herbaceous Plant Materials, Environmental Science and Management, and Commercial Nursery Management.
- Contributed to the development of the OSU Introduction to Horticulture website.
- Garden Center Technician since 9/98.
Ohio Florist Association Short Course - Tour Guide for Howlett Greenhouse during 2000 Short Course, Columbus, Ohio.


text:
Home » A REVIEW ON STABILITY GUIDELINES BY ICH AND USFDA GUIDELINES FOR NEW FORMULATION AND DOSAGE FORM
A REVIEW ON STABILITY GUIDELINES BY ICH AND USFDA GUIDELINES FOR NEW FORMULATION AND DOSAGE FORM
{ DOWNLOAD AS PDF }
ABOUT AUTHORS:
Anilkumar S. Chinchole1*, B.N.Poul2, C.V. Panchal1, D.V. Chavan1
1Department of Quality Assurance, Maharashtra College of Pharmacy, Nilanga, Latur, Maharashtra, India
2Principal of Maharashtra College of Pharmacy, Nilanga
Maharashtra College of Pharmacy, Nilanga, Latur, Maharashtra, India
*anilc14@gmail.com
Stability guidelines for new drug substance and new pharmaceutical formulations as per ICH and USP for the evaluation and consistency for new drug and pharmaceutical dosage form. The brief understanding of these guidelines can be easily recognized by this article. Stability testing Provide a evidence on how the quality of a drug substance or drug product varies with time under the influence of a variety of environmental factors such as temperature, humidity, and light. To establish a re-test period for the drug substance or a shelf life for the drug product and recommended storage conditions. Because physical, chemical or microbiological changes might impact the efficiency and security of the final product. To minimize the Adverse Effects Of Instability In Drug Products Loss of potency of drug such as Change in concentration of active drug, Alteration of bioavailability, Loss of content uniformity, Loss of pharmaceutical elegance and patient acceptability, Formation of toxic degradation products.
REFERENCE ID: PHARMATUTOR-ART-2215
PharmaTutor (ISSN: 2347 - 7881)
Received On: 03/05/2014; Accepted On: 01/06/2014; Published On: 01/08/2014
How to cite this article: AS Chinchole, B Poul, CV Panchal, DV Chavan; A Review on Stability Guidelines by ICH and USFDA Guidelines for New Formulation and Dosage form; PharmaTutor; 2014; 2(8); 32-53
Stability studies means?
Stability studies should include testing of those attributes of the drug substance that are susceptible to change during storage and are likely to influence quality, safety, and/or efficacy1.
Protocol of Stability
Prior to the submission of an original or supplemental NADA, an applicant may wish to submit a stability protocol for comment before committing to studies that will become a permanent part of the NADA. The protocol should contain an outline of the proposed plan to be used in generating stability data. The protocol should describe the type of product being tested, sampling process, duration and frequency of testing, number of samples and replicates per time interval, storage conditions (length of storage, type of storage, temperatures and packaging), methods of analysis (description or reference of published methods) with accompanying support data, if available, and other tests. The information listed in these guidelines should be incorporated as appropriate in the development of a plan.
GENERAL STABILITY CONSIDERATIONS
Definition of Active Ingredient
The active ingredient of an animal drug preparation is defined as that chemical whose biological, physiological, pharmacological, or chemical activities are claimed on the label to be beneficial for animals in normal or pathological conditions (diagnosis, prognosis, treatment, prophylaxis, therapy) or for animal production.
Strength (Potency)
The strength of a drug substance may be its concentration (quantity of the drug per unit measure), its potency, or both. The potency of a drug is a measurable (quantitative) extent of the biological, physiological, pharmacological, or chemical activities of the drug per unit weight or volume of the drug preparation.
Drug preparations are considered stable if the active ingredient can maintain its strength at the level specified on the label for the maximum anticipated shelf-life (the time period from the date of manufacture until administration to the animal) under environmental conditions likely to be encountered in actual use. However, few, if any, drug preparations maintain their full label-claimed strength under specified conditions. Therefore, allowances are made for some unavoidable deviations from drug levels declared on the label by designating specific limits for tolerable deviations.
A drug product is considered unstable when the drug substance (active ingredient) loses sufficient potency to adversely affect the safety or efficacy of the drug or falls outside labeled specifications as shown by stability-indicating methods. To properly evaluate the stability of a drug product, it is essential to determine the storage conditions under which the drug strength can be maintained in order to provide a safe and efficacious drug product. As a guide in determining drug strength in pharmaceutical dosage forms, the following is recognized by the scientific community:"Although there are exceptions, 90% of the labeled potency is generally recognized as the minimum acceptable potency level."
Drug Preparation
The active ingredient should be formulated in any drug preparation at 100% of label claim. An overage of the active ingredient may be permitted in a product should the need exist. All overages should be justified. The assay limits must account for the overage. The overage should not exceed the limits of 5% for antibiotics and 3% for non-antibiotic chemicals as established by the Center for Veterinary Medicine.
Chemical and Physical Properties
Strength is not the only criterion of drug product stability. Maintenance of various chemical and physical properties to preserve the effectiveness and safety of the drug is also important. Properties, such as physical appearance, crystalline form, particle size, solubility, disintegration rate, pH, sterility, viscosity, palatability (taste and odor), may be stability related and thus require testing and the setting of specific storage conditions and limits. In addition, tests may also be needed to determine the absence or presence of harmful degradation products.
Added Substances
Stability data on substances that are added to a drug preparation to enhance its stability, usefulness, physical or chemical properties or as an aid in manufacturing may be required. The type of substance(s) used, its purpose and its relationship to the active drug ingredient(s) and total drug preparation will determine if testing for the substance is required. Examples of added substances that may commonly be used are antioxidants, antibacterials, absorbants (bentonite), etc.
Changes made in the composition (formulation) or dosage form of the original or succeeding product(s) present a new drug product and will require generation of new stability data. Data requirements will depend on the nature and degree of change.
Any change requires an evaluation as to the effect on the stability of the products.
Correlation with Efficacy and Toxicity Studies
Stability studies supporting an application should be performed on the drug preparation in its final formulation whose efficacy and safety has been demonstrated. Any change made in an approved preparation requires consideration of the effects on the efficacy and safety of the "changed" drug product. Degradation Products Degradation products that occur during storage (under shelf-life testing) should be identified. These products should be thoroughly investigated and evaluated for safety and toxicology purposes. The presence of degradation products may require additional safety and efficacy studies.
Product Stability Parameters
The established regulatory registration (NADA or NDA) specifications or Compendial standards are to be used for determining the stability of the products. There can be only one set of standards. Samples of products (from production lots) on stability should be representative of those in the market place. Expiration dating is based on the ability of the product to be measured over a certain period of time against the established specifications or standards1, 2.
STABILITY1, 9
In stability is defined as "the extent to which a preparation retains, within specified limits, and throughout its period of storage and use, the same properties and characteristics that it possessed at the time of compounding." This chapter defines beyond-use date as "the date after which a compounded preparation is not to be used and is determined from the date the preparation is compounded. Stability testing is used to determine a beyond-use date, which is required by USP guidelines to be on the label or package of a compounded preparation. The terms stability, shelf life, and beyond-use date can be used interchangeably when referring to compounded preparations. The term expiration date is used when referring to manufactured products. Pharmaceutical Compounding Sterile Preparations states, "It should be recognized that the truly valid evidence of stability for predicting beyond use dating can be obtained only through product-specific experimental studies." It is important to remember that the analytical method employed is key to determining stability versus potency. Once again, a stability-indicating method must be used to establish stability. Furthermore, a potency test that used stability-indicating methods can be used to determine stability as well as Stability testing usually includes method development, method validation, and a stability study. The method must separate the active ingredient from its degradants and impurities, as well as any other excipients potencyin the preparation. This is done by force degrading the active ingredient and inactive ingredients to ensure that no degradants interfere with the analysis. In the process of force degradation, the compound is exposed to high heat and humidity, UV radiation, an acid, a base, and peroxide. It is this step that differentiates a stability indicating test from a simple potency test.
Stability can be determined from this type of study, simply because stability-indicating methods were used in the analysis. Method validation ensures that the method meets certain criteria. The typical analytical characteristics used in method validation include accuracy, precision, specificity, detection limit, quantitation limit, linearity, range, and ruggedness, as outlinedin. The stability study includes storing the preparation in stability chambers, testing it at predetermined time points, and then determining stability. These time points may be specified by the compounder or dictated by the particular compound. Once again, it is crucial to understand that the methods used to determine stability must be stability indicating. Quality assurance programs are essential to establishing appropriate standards for compounded preparations. The specificprogram implemented is up to the compounding pharmacy but should include a standard operating procedure, documentation, verification, and testing as outlined in USP Chapter.The standards of the Pharmacy Compounding Accreditation Board state that "a pharmacy must provide documentation of the basis for its determination of the beyond-use date assigned to its compounded preparation."
ICH guidelines 2
1. Stability Testing of New Drug Substances and ProductsQ1A(R2)
2. Stability Testing: Photostability Testing of New Drug Substances and Products Q1B
3. Stability Testing for New Dosage Forms(Q1C)
4. Bracketing and Matrixing Designs for Stability Testing of New Drug Substances and Products(Q1D)
5. Evaluation for Stability Data(Q1E)
6. Stability Data Package for Registration Applications in Climatic Zones III and IV (Q1F)2.
1. Stability Testing of New Drug Substances and Products2,3
Objectives of the Guideline
The following guideline is a revised version of the ICH Q1A guideline and defines the stability data package for a new drug substance or drug product that is sufficient for a registration application within the three regions of the EC, Japan, and the United States. It does not seek necessarily to cover the testing for registration in or export to other areas of the world.
The guideline seeks to exemplify the core stability data package for new drug substances and products, but leaves sufficient flexibility to encompass the variety of different practical situations that may be encountered due to specific scientific considerations and characteristics of the materials being evaluated. Alternative approaches can be used when there are scientifically justifiable reasons.
Scope of the Guideline
The guideline addresses the information to be submitted in registration applications for new molecular entities and associated drug products. This guideline does not currently seek to cover the information to be submitted for abbreviated or abridged applications, variations, clinical trial applications, etc.
Specific details of the sampling and testing for particular dosage forms in their proposed container closures are not covered in this guideline.
Further guidance on new dosage forms and on biotechnological/biological products can be found in ICH guidelines Q1C and Q5C, respectively.
The purpose of stability testing is to provide evidence on how the quality of a drug substance or drug product varies with time under the influence of a variety of environmental factors such as temperature, humidity, and light, and to establish a re-test period for the drug substance or a shelf life for the drug product and recommended storage conditions.
The choice of test conditions defined in this guideline is based on an analysis of the effects of climatic conditions in the three regions of the EC, Japan and the United States. The mean kinetic temperature in any part of the world can be derived from climatic data, and the world can be divided into four climatic zones, I-IV. This guideline addresses climatic zones I and II. The principle has been established that stability information generated in any one of the three regions of the EC, Japan and the United States would be mutually acceptable to the other two regions, provided the information is consistent with this guideline and the labeling is in accord with national/regional requirements.
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redpajama_set_name: RedPajamaCommonCrawl


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Integrity. Experience. Law.
Anna Polko Clark
Philip M. Coffin III
Andrew S. Davis
H. Peter Del Bianco, Jr.
Jonathan T. Harris
John F. Lambert, Jr.
Samuel K. Rudman
Jeffrey D. Russell
Maureen M. Sturtevant
Abigail C. Varga
Amy J. Visentin
Caitlin R. Wahrer
Maine Civil Litigation & Professional, Products Liability Attorney | H. Peter Del Bianco, Jr.
H. Peter Del Bianco, Jr. focuses on general civil litigation cases with an emphasis on insurance defense & coverage, mass tort litigation, and other complex litigation.
Email / Tel.: 207.370.3003 | Cell: 207.831.8224
Peter's practice focuses on general civil litigation with an emphasis on insurance defense and coverage, mass tort litigation and other complex litigation. Since joining Lambert Coffin in 1988, Peter has successfully represented business and individual clients in state and federal courts, in both jury and bench trials. He has appeared at all levels of the federal and state court systems, and before multiple state administrative agencies, including the Workers' Compensation Board, the Unemployment Board, and several municipal zoning and planning boards.
"I belong to a firm that aspires to, and achieves, excellence in the practice of law. The hunger to be the best, and the satisfaction of winning, drives us all to extraordinary efforts for our clients, without regard to the size of the case."
Peter's clients range from individuals, to small Maine-based businesses, to large multi-national Fortune 500 companies with a Maine presence. He has represented and currently represents pharmaceutical and tobacco companies in class action product liability suits in Maine. Peter regularly handles insurance defense and insurance coverage matters for several large regional and national carriers, and advises on regulatory matters for these clients as well. He also handles the full range of workers' compensation litigation for several self-insured multinational clients with significant operations in Maine, and frequently counsels clients on employment-related issues.
Peter is a past president and long-time board member of the American Civil Liberties Union of Maine. He has an abiding interest in civil rights and civil liberties, and he has significant experience both defending and prosecuting Section 1983 actions. Peter and his partner Phil Coffin currently serve as counsel to the Maine Chiefs of Police, provide annual training to the Chiefs on a range of topics, and regularly represent police and other municipal executives in employment disputes.
While in college, Peter was an amateur boxer and competed in the Golden Glove Competition in Lowell, MA. He then played competitive first side rugby for the Boston Rugby Club and Portland RFC over the next 20 years. He still laces up the boots and gloves on occasion. Peter and his wife Ellen live in Cumberland. They have three children, college age and beyond. Peter recently took a four month sabbatical to hike half the Appalachian Trail with one of them. When not working, Peter and Ellen often are skiing, hiking, biking, or canoeing, and sometimes tending to their garden.
Print Bio
HONORS AND DISTINCTIONS
Selected for SuperLawyers
University of Maryland, B.A.
Boston University School of Law, J.D., cum laude
Editor, Boston University
International Law Journal
State of Maine
for the District of Maine
United States Court of Appeals
First Circuit
Maine Superior Court
Maine State Bar Association
Cumberland County Bar Association
Maine Trial Lawyers Association
Defense Research Institute
Tri-State Defense Lawyers
Past President American Civil Liberties Union of Maine
Little League Umpire
The experience of yesterday / the energy of tomorrow
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Portland, Maine | Blue Hill, Maine
Lambert Coffin is a general practice law firm that provides legal advice to individuals and businesses alike.
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Hi! My name is Giorgia and I am in my third year of my primary school teaching degree and also work part-time as a waitress. I am a very responsible, conscientious and tidy person. I am also a big animal lover and have two cats and a dog of my own. I enjoy house sitting as it allows me to experience new places around the area I live in.


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The Cinematic Journey: 'Birdman'
Posted by Kaitlin Sansoucie on January 23, 2015 April 30, 2019
I often find myself wrapped up in writing about Story in film. I like Story. I get into the grit and value of the feels of movies- the way they play emotions and the way writers employ outside influences. Sometimes, though, there's a story that screams cinema beyond interests of plot and dialogue- pacing and motion, the way the camera moves in, out and around…a story so beautifully envisioned on camera that I can't separate the underbelly plot from the visceral montage sequences and the blend of sounds and music throughout. 'Birdman' is one of those films that refuses to be pulled limb from limb. You watch, it drives: welcome to the cinematic journey.
At this point, you may already know that in this film Michael Keaton plays celebrity actor Riggan Thomson who's claim to fame is his successful role, "Birdman"- a superhero of Batman-like fame in filmmaker Iñárritu's stage-small world of Times Square NYC. We start watching when Thomson is struggling to gain fanfare for his first Broadway production. Audiences are immediately positioned in the midst of his peculiar delusion: he is Birdman. His security as a performer is shot because he never truly acted, he was just famous. This is about a celebrity proving his chops in the face of no one wondering. It's about an actor proving himself to himself in front of everyone who will look- they validate his world by watching him perform for the sake of his own image. So, he levitates, he breaks glass, he crushes unworthy stage-fellows, and, as he faces more intense naysaying, he blows up buildings and flies. Interestingly, I mean he thinks he does- we don't see him commit unearthly acts. The camera swerves to his hip or head unsteadily transferring us from his thoughts of power to his imagining of being Birdman- the character everyone knows and paid to see in theaters, but whom no one takes seriously. The strange juxtaposition is more than an artistic musing in film form. Iñárritu explores the question of celebrity versus "true" performance so expertly that it borders looking political…almost like an attack on materialism.
In order to make a good impression, Thomson and his right-hand man (lawyer) Jake, played by Zach Galafianakis, employ lauded stage actors to support Thomson's lead in the show. Edward Norton plays Mike, a mentally bloated but talented method actor who exists in flesh and blood only on stage. We see the examples of this as he walks his way around the winding fun house that is backstage at a Broadway theater house: he hits on anyone he wants, tests his colleagues, and while can't he get it up in private he bears no hesitation to do so on stage. He is the Theater Actor- the one in his element on a stage, live. Thomson has come to be recognized on the street in the name of his fame, but he has not gained the inner feeling of success that drives Mike. They mirror each other: the two halves of the vision of success that can't seem to come together without dramatic happenings leading them into fantasy. The camera spins and turns and closes in on camera lens to allow us to feel as claustrophobically driven to understand the grind of the protagonist in the made-up but very realistic world built by the filmmaker: painted in muddy green and violent yellow-tinged shadows, the aggressive dance of values between Thomson and his daughter (played with spectacular balls by Emma Stone), the peacock punches Thomson shares with Method Actor Mike, his gentle understanding of the leading lady, Lesley, played by Naomi Watts- a gritty, applause worthy performance, indeed.
Once Thomson reaches the height of his delusions, when instead of falling on his face he dramatically falls *through* his face by accidentally shooting off his own nose onstage, in that achy blue tainted hospital room, the story curves in on itself. He's told by his lawyer/friend that he succeeded. How? He got everyone's attention. He got hundreds of thousands of followers on Twitter. He held attention for longer than a single string of 140 characters: 24 hours of renewed fame, coinciding with his stage performance. This is success. Of course this is anticlimactic for the protagonist who wanted to be the real Birdman: The Actor, with passion and palpable talent who is widely RT'd. And that's when, upon reflection, the bandaged, very Twitter famous Riggan Thomson exits through the window. By the look on his daughter's face- pure joy- it is not a jump, but a soaring leap. We end where we started with him. We imagine with him that he's flying over New York, above the masses who worship him not only with their dollars and precious time, but like a god. Success.
BirdmanEdward NortonfilmKevin Costner
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Q: Meaning of "virtually" in the following sentence?
The list of things I believe,though I have no evidence for the truth
  of them, is, if not infinite, virtually endless.

I found two main relevant senses:
virtually:

1 : almost entirely : NEARLY
2 : for all practical purposes

Which one is the meaning in the above sentence? Generally, how to find out which of these meaning is the case, as the context does not always help?

A: The OED combines these two definitions:

1b. In effect, although not according to strict definition; to all intents and purposes; as good as; practically. Later frequently in weakened use: nearly, almost.

Personally, I think that is a better way to understand the term, and how it is regarded in English. These are not two separate meanings with separate etymologies, but the "almost entirely" meaning is simply a weakening of the "for all practical purposes" meaning. It's not hard to see that often when A is "effectively" or "for all practical purposes" B, it is so because A is "nearly" B in some sense. There will be some exceptions (and this is arguably one of them, see below) but there is a lot of overlap between the two meanings.*
This leaves open the question of which is being used in your example, although it illustrates why the difference between the two meanings is regarded as being razor-thin.
With that in mind, three answers:
1) This seems like a classic case of a distinction without a difference. Given that the statement is almost certainly not meant to be taken in a completely literal manner, nailing down which shade of the definition was in the speaker's mind doesn't seem to add much to the understanding of the meaning.
2) The "for all practical purposes" seems like the definition that would be slightly more useful in making the speaker's point. Something could be infinite "for all practical purposes" or "as good as" infinite, without being demonstrated to be literally infinite. It is possible that the context might indicate that the speaker was actually making a claim about the literal numerical vastness of the unsupported things he or she believes, but that seems to be less important than a more general point about his or her credulity/open-mindedness.
3) Strictly speaking, it's impossible for something to be "nearly infinite" in a literal sense; it either is or isn't. Logically, the speaker must mean "infinite for all intents and purposes".
(I realize I've elided infinite and endless through this answer, even though the quote technically modifies endless with virtually, but I don't think it changes any of the points.)
*I would argue, based entirely off of my own intuition, and I have no references to back it up, that the two meanings are even closer than this implies: that even when we use virtually to simply mean nearly or almost that we only use it when the difference doesn't much matter or when we are minimizing the difference. If someone collapses short of the finish line, we could say that he nearly finished the race, but not that he virtually finished, because the whole point of a race is to cross the finish line, unless we were intentionally trying to minimize the fact that he didn't finish.

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fosun pharma issues corporate bonds of rmb3 billion-凯发k8娱乐app下载
fosun pharma issues corporate bonds of rmb3 billion
shanghai fosun pharmaceutical (group) co.,ltd(fosun pharma, or the company). announced that the company has completed the issuance of the first tranche of corporate bonds on 4 march 2016 in a principle amount of rmb1.5 billion, which can be over-allotted for up to another rmb1.5 billion. the development prospect of fosun pharma has been generally recognized by investors and the bonds will ultimately raise rmb3 billion in total with a coupon rate at 3.35%. according to its announcement, the bonds has a term of five years with the issuer's option to raise the coupon rate after the end of the third year and the investors' entitlement to sell back the bonds. the proceeds from the issuance of the bonds are mainly to be used for the company to optimize debt structure and to replenish the general working capital.
the bonds has received "aaa" rating and the corporate credit rating is "aaa".
established in 1994, fosun pharma (stock code: 600196-sh, 02196-hk) is a leading healthcare group in the prc.
fosun pharma strategically covers important segments of the healthcare industry value-chain, including research and development, pharmaceutical manufacturing, medical diagnosis, medical devices, pharmaceutical distribution and retail, and healthcare services, making contribution to improving public health. fosun pharma maintains a national recognized enterprise technology centre and a highly capable international r&d team, focusing on innovation and research of therapeutic areas including cardiovascular system, metabolism and digestive tract system, central nervous system, blood system, anti-tumor and anti-infection diseases.
with its commitment to innovation for good health and creating a better future, fosun pharma will continue insisting on the strategic development approach of "organic growth with external expansion and integrated business operation". the company strives to be one of the first-class enterprises in the global healthcare market.
previous:"fosun pharma 2014 corporate social responsibility report" ranked the first in the pharmaceutical industry next:fosun pharma announced rmb538 million investment on the restructuring of xuzhou coal mining group's hospital
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As a fan I go to see the riders compete, but there is much more to see at a big pro tour than just a pretty face and a fast pair of shaved legs. There are bikes, and there are some very colorful useful cars. Perhaps you have thought at some point, just as I have, "my car is so boring, I need a paint job like that." Let's go on down the road with a pictorial journey of the varied graphic designs of the professional cycling team cars. Which one would you chose?
I want more than one. I'd like a car covered with jelly beans for Monday morning and a Leopard Trek sleek design for Friday night, and a HTC mini bus for weekend warrior extravaganzas. I don't need, nor do I want, that broom wagon anywhere near me.
I'd like to experience what it would be like to hang onto the backend of a moto (motorcycle) during a race. However I would not want to be one of those mechanics who carry a team bike over their shoulder for hours while on the back of a support moto going up a small winding mountain pass in Italy. I would enjoy being on the other end of a sticky bidon with Tom Boonen holding on tight.
I'm not certain I would pay $2000 to ride in a VIP car during a Tour, unless I won it in a contest. If I were inside a team car, racing down the street through throngs of people, I'm not certain I could refrain from being the worst kind of backseat driver. "Ooh watch out for that ... whoa, was that a cow or a fan ... brake into the corner, accelerate out of the corner ... whoa, I guess that works too ... can you keep two hands on the steering wheel please ... do you have to talk on that radio all the time ... I have to pee."
I love taking pictures of everything I see at a race, I have to share these pictures somehow, they are so cool. All photos from 2011 and by PedalDancer.com, Kenny Rakestraw, and SyS in France (we get around as a family!).
The vehicles used by a ProTeam vary depending on which country they are racing in. Arranging the cars, buses, trucks and vans used by a team is part of the job of team logistics. The make, model, size, number, and whether the vehicle is owned or rented by the team all vary depending on the location and the race.
Some team vehicles are stored in Europe or America and driven the distance to the race. Often the trucks, buses, vans and cars are rented or leased for the period of time needed. This explains why the team car models vary in the USA compared to models used in Europe. Obviously the team budget is sometimes reflected in the size of the bus.
If a Tour or race has a car manufacturer as a sponsor, the race sponsor might override the team sponsored car manufacturer. This is the reason why Leopard Trek placed a simple decal on their Nissan vehicles used for the Amgen Tour of California, because Nissan sponsored the race, but there real team sponsor is Mercedes. Mercedes are used as team cars by Leopard Trek for the European races. Although BMC drove their team sponsored Acura cars in California but not in Europe.
Because the cars are often rented from a city close to the race start, the license plates give away the secret. For the Tour of California many of the vehicle license plates were from Nevada. The rented vehicles used by the team and race organizers will have team graphic decals added by local automobile graphic companies. For example Summit Graphics in Commerce City, Colorado is doing some of the official car graphics for the USA Pro Cycling Challenge. These companies employ graphic designers who work with the race or team logos to achieve a consistent brand look. Sometimes the team must keep it simple, as this Saxo-Bank team bus did at the 2010 Tour of California.
Ask Nick: Caravan ordering - what determines the order the team cars are in when following the peloton.
Ask Nick: Calling Car 1, come in Car 1 - Since there are two chase cars, what's the difference between Car 1 and Car 2?
The Skoda wagon - is it the best team car for a mechanic? Who is ŝkoda?


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Naples: Herculaneum Skip-the-Line Tour with Archaeologist
Popular Activities in Ercolano
From Naples: Pompeii, Herculaneum, and Vesuvius Group Tour
Naples: Full-Day Pompeii & Herculaneum Wine Tasting Tour
From Naples: 2-Hour Herculaneum Kid-Friendly Tour
Private Pompeii Herculaneum Tour
Herculaneum Ruins Day Trip from Naples
From Naples: Pompeii, Herculaneum, and Vesuvius Private Tour
Our most recommended Ercolano Activities
1. Naples: Herculaneum Skip-the-Line Tour with Archaeologist
This tour will take you on a guided visit of the world's best preserved Roman city, Herculaneum. This was a rich city of merchants and nobility, whose lives ended dramatically fast with the eruption of Mount Vesuvius nearly 2,000 years ago. See the waterfront, where the remains of more than 300 people lie, who died trying to escape by sea. Explore the Samnite house, the thermal baths, the Temple of the Augustales, and the Forum. Discover the house of Neptune and Amphitrite, the Gymnasium, and much more. During this experience you can see not only stone, marble, and ceramics that survived the eruption, but also carbonized wood, and paintings and mosaics even more exquisite than those found in Pompeii. Learn about life in this city, and the blast that destroyed it, on this 2-hour guided tour.
3. From Naples: Pompeii, Herculaneum, and Vesuvius Group Tour
See the ruins at Pompeii and Herculaneum before heading to the top of the volcano that destroyed them on this trip from Naples. Choose from the option to be picked up at Stazione Marittima or from the Hotel Ramada at 8:30 AM. Travel to Pompeii, the impressive open-air museum that holds more than 2000 years of history. Step into the past as you walk through streets that have been preserved by volcanic material from Vesuvius. Continue to Herculaneum, which was named after Hercules and completely submerged by volcanic mud. Wander through the streets and see colorful mosaics. View the ancient summer residences of Roman Patricians. Finally, stop at Vesuvius, the volcano responsible for the destruction of so many cities. Stroll around its crater and enjoy panoramic views of Naples. The driver will be at your complete disposal during the tour, explaining to you onboard the vehicle, everything you need to know about the places you will visit, and once on site, he will give you free time to spend as you like.
4. Naples: Neapolitan Hands On Cooking Class at Herculaneum
The day will start with a pickup from the established meeting point. You will be transferred to Herculaneum, where your experience will take place. During the cooking class you will learn local recipes and also learn about the Neapolitan cooking tradition. You will prepare a 3 course menu with the assistance of an expert chef. At the end of the experience you will enjoy your hand made dishes and taste a glass of wine, admiring the panoramic views of Naples and of the majestic Vesuvius. Monday: Gnocchi alla sorrentina – Codfish – Shortcrust pastry Wednesday: Fresella with seafood – Stuffed Calamari – Zeppola di San Giuseppe Friday: Pizza – Crocchè- Torta caprese
5. 2-Hour Private Tour of the Ruins of Herculaneum
See the ruins of Herculaneum, the smaller, but no less impressive, sister of Pompeii, frozen in time by the same devastating volcanic eruption of August 24th 79 AD. Left buried under the rubble of ash until the 1700s, its discovery stunned the world. All of the ancient town lies at the bottom of an archaeological hole, about 75 feet deep. Getting closer, see the area of the marina where 300 human skeletons were found along with a boat (on display at weekends). Discover the garden of the "House of the Albergo", where quince trees have been replanted following evidence of carbonized roots of the ancient fruit tree. Your next stop is the Council Hall of the Augustali, where beautiful frescoes depict Hercules. Visit the mosaics in the House of Neptune and Amphitrite, and the neighboring store where food and wine containers, carbonised by the volcano, still hang on the walls! Go to the anceint spa, still covered with mosaics from the Roman saunas, gyms, hot rooms, and cold tubs. Finally, see the most spectacular villa of Herculaneum at Villa dei Cervi, with its luxurious mosaics, frescoes, and statues.
6. From Naples: 2-Hour Herculaneum Kid-Friendly Tour
This tour is designed for capturing the attention of the kids and guiding them through the discovery of Herculaneum, one of the most fascinating archaeological sites in the world. Everything is well-preserved and the kids can walk around the town, enter houses, temples, theater and truly feel what it was like to live in Roman times. Your guide will focus on the their needs and attention and, with the use of tablets, reconstructions and multimedia material, they will surely have the best Herculaneum experience ever. This is a walking tour, no transportation will be included. Visit the Northern Cardo (road oriented north-south), the House of the Skeleton, thermopolium (restaurant food), men's thermal bath, the Temple of Augustali, forum (main square), House of the Black Saloon, House of Neptune and Amphitrite, House of Bel Cortile, the Samnite House, the House of the Wooden Partition, the bakery, the gym, the Home of the Bucks, the Marina gate terrace of Marcus Nonius Balbus and the beach where hundreds of skeletons of the victims of the eruption were discovered.
7. Herculaneum Ruins Day Trip from Naples
Travel to the entrance of the Herculaneum ruins on a shuttle bus service from central Naples. Enter the archeological site without delay with your skip-the-line ticket. Spend the day exploring the city that was covered with mud and lava during the explosion of Mount Vesuvius in 79 A. D. Walk past the buildings of the ancient Roman town destroyed by the eruption. See intact wooden structures that were dwellings with expensive furnishings and ornamentation. Beyond the beautiful villas of Herculaneum, visit important public buildings and the thermal baths as well. Take your time as you explore and discover the history, heritage, and beauty of the city.
9. Private Pompeii Herculaneum Tour
Visit the top sites in Campania at your own pace on this private tour from Naples to Pompeii, Herculaneum, and Mount Vesuvius. Learn about the history and culture of the three stops from a professional guide. Travel to each stop in a comfortable airconditioned Mercedes and take your time to explore. Wander the ancient streets of Pompeii, a city buried by the sudden eruption of Mt Vesuvius in 79 AD. See ruins unearthed from layers of dust, lava, and rock, including the ancient Roman Forum. Walk through the well-preserved ancient Roman town of Herculaneum, destroyed by volcanic pyroclastic flows from the Vesuvius eruption. Learn about the Roman skeletal and physical remains discovered at the site in 1981. Travel to the volcano itself, Mt. Vesuvius, still an active volcano in Campania that overlooks the region.
10. From Naples: Pompeii, Herculaneum, and Vesuvius Private Tour
Visit the ruins at Pompeii and Herculaneum before heading to the top of the volcano that destroyed them, Mt. Vesuvius, all on this private trip starting from Naples. Enjoy live commentary on board and free time during stops. Depending on your group size, choose to travel in a sedan vehicle for 1 to 2 passengers or a minivan for 3 to 8 passengers, both air-conditioned for maximum comfort during your tour. Travel first to Pompeii, the impressive open-air museum that holds more than 2000 years of history. Step into the past as you walk through streets that have been preserved by volcanic material from Vesuvius. Continue to Herculaneum, named after Hercules and completely submerged by volcanic mud. Wander through the streets and see colorful mosaics. View the ancient summer residences of Roman Patricians. Finally, stop at Mt. Vesuvius, the volcano responsible for the destruction of so many cities. Stroll around its crater and enjoy panoramic views of Naples. During the entire tour, your driver will be at your complete disposal, explaining to you on board the vehicle everything you need to know about the places you will visit. At each stop, you'll get free time to spend as you like.
Luciano Leone was a very special guide. He made sure everyone's questions were answered and he made a point to keep the several young children on our tour interested. I'm so glad I paid for the tour rather than visiting the site on my own.
Naples: Herculaneum Skip-the-Line Tour with Archaeologist Reviewed by David, 12/30/2021
Michele Lamberti with Askos Tours was a great guide. He was very knowledgeable and great storyteller. We went on a Sunday and the other couple in our group didn't show so Michele gave us a private tour which brought Herculaneum to life.
Naples: Herculaneum Skip-the-Line Tour with Archaeologist Reviewed by Teresa, 11/28/2021
Diego was a fantastic guide. We visited on a rainy day, but he still really brought it to life. I would definitely recommend.
Naples: Herculaneum Skip-the-Line Tour with Archaeologist Reviewed by Minna, 12/5/2021
Meet with our guide Diego, who was really knowledgeable and showed us around the site with a lot of passion
Naples: Herculaneum Skip-the-Line Tour with Archaeologist Reviewed by Alice, 12/28/2021


Deputy Prime Minister Bob Loughman spoke after the motion was defeated 31 votes to 19 in parliament on Tuesday.
A special session was called for the motion to be debated and one by one MPs from the government side of the house who signed the motion, indicated they still backed the government.
The Leader of the Opposition, Ishmael Kalsakau, has warned he is going to pursue the matter in court and he has alleged that bribes took place.


Browse Relevant Sites & Find What Hath God Wrought Meaning. All Here!
WHAT HATH GOD Wrought The Transformation of America, 1815-1848 | DANIEL WALKER HOWE: Between the War of 1812 and the conquest of Mexico in 1848, the size of the United States doubled, a communications and transportation revolution took place, Protestantism spurred reform movements, and the meaning of democracy came under question.
The phrase "what hath God wrought?" became the first words that inventor Samuel F.B. Morse transmitted at the inauguration of the Washington-to-Baltimore telegraph line on May 24, 1844. According to the History Channel, the sentence comes from Numbers 23:23 in the King James Version of the Bible.
What does what hath God wrought mean? Looking for the meaning or definition of the word what hath God wrought? Here's what it means. Interjection (archaic) An expression of wonder and marvel at something. Find more words!
"What hath God wrought" was the first public American Morse code message sent in 1844, from Baltimore to Washington D.C.. It's also the title of a Pulitzer prize winning History of the US 1815-1848.
What hath God wrought! or, "what God doeth." The meaning seems to be that augury and divination were useless and vain in the case of Israel, because God himself declared and would declare his mighty acts in behalf of his people, and that by no uncertain vaticination, but by open declaration.


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Statistics: Number of Cars imported last Year to Bosnia-Herzegovina
February 11, 2020 5:30 PM by Y.Z
Nearly one billion BAM worth of cars were imported in Bosnia-Herzegovina in the previous year, which represents a record over the last ten years, Capital portal learned.
Last year, 69,077 cars were imported, which is less than in previous years, but the value of the cars increased.
The most expensive vehicle to arrive in Bosnia was the Bentley Continental GT Coupe, which was paid 422,714 BAM.
The country earned 72,000 BAM from this luxury car for taxes.
The total value of imported cars in BiH last year amounted to 958.1 million BAM, and 204 million BAM in taxes was paid.
Of the total imported cars, 58,645 were used, while 10,432 were new vehicles. After the Bentley, on the list of the most expensive cars imported in BiH second is Rolls Royce Ghost Family, for which 336,696 BAM was given, of which the country received 57,255 BAM. In the third place is the "Bentley Bentayaga V8" whose value is 309.013 BAM, and the owner paid 52.602 BAM.
Statistics show that over the past 10 years the number of imported cars has increased, but also their value, except for the previous year when fewer vehicles were imported. Thus, in 2010, 384 million BAM was allocated for imported cars, while in 2019 this amount increased to almost one billion BAM, Biznis Info reports.
Tags: #BiH, #cars, #import


Naomi Blacklock, Parallel Presence, 2016-ongoing. Brass, Tasmanian oak wood, glass mirror, beeswax candles, salt with sound created through effect pedals, contact microphone, vocal microphone, amplifier, dimensions variable. Performance documentation from Outer Space, Brisbane, 31 October, 2018. Image courtesy the artist.


Special thanks to Kim Poulton for sharing her daughter Faith's story to inspire this presentation. Faith's story can be read HERE.
Does Fetal Membrane Stripping Require Informed Consent?
Left: The actual display with suggested topics on post-its so that researchers could take the ones that spoke to them.
How Do Microorganisms Gain Access into the Upper Reproductive Tract?


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Kings square off with familiar foes Detroit Red…
Kings square off with familiar foes Detroit Red Wings
The Kings and Red Wings, who play Saturday night at Crypto.com Arena, aren't that different the past several years
The Kings' Alex Iafallo, right, celebrates his winning goal with Anze Kopitar as Detroit's Dylan Larkin skates by during an overtime victory November 14, 2019, in Los Angeles. (Photo by Harry How/Getty Images)
By Andrew Knoll |
Having found consistency in their game if not their lineup, the Kings will next contend with a Detroit Red Wings franchise whose rebuild has mirrored their own in many ways.
The short-handed Kings played three of their better games of the season, despite missing four players due to COVID protocols and four more with injuries in their most recent outing. They lost battles of special teams and opportunism that caused them to go to overtime in a win over Vancouver and lose a game against Nashville despite dominating most of both matches. They wedged a commanding victory over Philadelphia in between.
Constancy and competitiveness have been there, and so has another important element of their potential success.
"I don't question the character of our group one bit. There's nights where we question the input into the game, maybe the effort, we get lazy at times, but the character is there," Kings coach Todd McLellan said.
Detroit and the Kings are seeking to return to their peaks of the not-so-distant past, but with a largely different group of players in the Kings' case and an entirely different one in Detroit's.
The Kings were a competitive fixture through most of the 2010s, winning two Stanley Cups and cementing their core's place in franchise lore. Detroit took that several steps further, making the playoffs in every postseason for a quarter century between 1991 and 2016 and winning four Stanley Cups.
But neither has made the playoffs recently, with the Kings missing three straight and the Red Wings failing to qualify for the last five postseasons. They both earned the ignominious distinction of being among the teams that did not make the cut for the 2020 play-in tournament that featured 24 of the NHL's 31 clubs.
Today, however, both teams are under the stewardship of Hall of Fame players who have moved from ice level to the front office in an effort to rekindle the spark near Hollywood and in Hockey Town, respectively.
Former Kings defenseman Rob Blake assumed control as the luster faded from Stanley Cups in 2012 and 2014, leading to the dismissal of the architect of those teams, Dean Lombardi, and his trusted coach, the renowned motivator Darryl Sutter. Arriving on a scene that was getting ugly – the Kings had over-extended themselves in trades, missed on some key draft picks and generally left an aging roster in an evolving league with limited prospects in the organization's lower levels – Blake has since focused on diversified moves to bolster organizational depth while remaining committed to some core veterans.
Blake recently told The Fourth Period's Dennis Bernstein that the Kings could be buyers at the trade deadline and that, for his part, there was desire and expectation to return next year with a new contract.
"(Team President) Luc (Robitaille) and I have a really good relationship. It goes back to the days we played as teammates," Blake said. "We've been very up front that, listen, let's let this year go, we'll figure things out at the end of the year, make sure we're going in the right direction, continue pushing on what we want to do and what we want to accomplish. We'll tackle that. There's lots of time."
Detroit has its own legend in the executive suite, former center Steve Yzerman, whose captaincy stretched from 1987 to 2006, encompassing three of Detroit's four Cups in the expansion era. After reviving a languished franchise that had made the playoffs only twice from 1967 to 1983 as a player, he has done the same as an executive over the past three seasons.
Like the Kings, Detroit sat just one point out of the playoffs entering Friday's games. That's a far cry from the seasons on either side of the return of Yzerman, who had been busy constructing most of Tampa Bay's two Cup-winning rosters.
In 2018-19, Detroit finished fourth from last in the league and then dead last the following season. Even so, their lottery luck was limited as they picked fourth rather than first overall, scooping up winger Lucas Raymond. A year earlier, Yzerman had stunned casual observers with the selection of lesser-known defenseman Moritz Seider at No. 6 overall.
Seider was the rookie of the month for October and Raymond garnered the honor in November. Raymond leads all rookies in scoring and Seider ranks third as well as first among rookie defensemen.
Whicker: Quinton Byfield's return spices up Kings' season
Kings can't overcome miscues against Avalanche
Kings' Quinton Byfield resumes long-awaited NHL career tonight
Kings look to rest, regroup before facing Avalanche
Flat third period costs Kings against Lightning
The Wings are led by team captain Dylan Larkin, who tops the team in points, goals and shots. Goalie Alex Nedeljkovic, acquired for a bargain price from the Carolina Hurricanes, has turned in some mixed performances statistically behind a young roster. On the whole, he has given the Wings a level of stability and ability unseen in their net in several seasons.
Unlike the Kings, who have at least four players in COVID protocols, Detroit has a near full complement of players and none in protocols.
DETROIT AT KINGS
When: Saturday, 7:30 p.m.
Where: Crypto.com Arena
TV/Radio: Bally Sports West / iHeartRadio
Andrew Knoll
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Academy Award Winner and When We Rise Creator Dustin Lance Black Discusses His Writing Process and Creating Stories for Hollywood
GLG Fact Sheet (PDF)
GLG FAQ (PDF)
GLG Timeline
GLG Compliance Framework
"Tell a Good Story That Changes People"
Interviewed in GLG's Video Series, Anatomy of a Decision
New York, New York; June 12, 2017 — GLG (Gerson Lehrman Group, Inc.), today released a new video with Academy Award® winning screenwriter and filmmaker Dustin Lance Black, as part of its Anatomy of a Decision video series. Black explains how he approaches the writing process and how to make a project commercially viable in Hollywood, saying, "If you want to tell a story that draws emotion in a universal way, the way you do that isn't by making it general, you make it really, really specific." Black adds, "Tell a good story that changes people."
Black won the Academy Award® for best original screenplay for his work on the motion picture Milk, and more recently created the eight hour ABC TV mini-series When We Rise, which chronicled key moments in the LGBT rights movement. Interviewed by GLG Head of Public Affairs Richard Socarides, Black discusses how to turn a passion project into something with commercial appeal, saying, "Specificity is what makes the unusual universal."
Of When We Rise, Black says, "The idea of the film is that we are strongest when we march arm in arm with other people of diversity." Black also shares what drives him to be a storyteller, "If we're moving the needle each day with the story we're telling, I've got a reason to get out of bed. And there are so many necessary stories; I don't think I've slept in in 15 years."
"Each of the videos in our series features an industry leader who has had to make tough decisions, and nowhere is that more true than in the creative process" said Richard Socarides, Head of Public Affairs for GLG. "Black's video continues to expand the breadth of topics and industries we explore."
Black, best known for his work on Milk, and this year's When We Rise, began his career directing documentaries and commercials. Then, he was a writer and co-producer on HBO's Emmy® and Golden Globe® nominated Big Love, and later earned a "10 Best of the Year" award from the American Film Institute for his screenplay for J. Edgar. Black has served on the board of the Trevor Project, which works to prevent teen suicides, and is also a founding board member of the American Foundation for Equal Rights (AFER).
All of the videos in GLG's Anatomy of a Decision series are available online without charge, including interviews with: Jill Abramson, former Executive Editor of The New York Times; Jeff Kindler, former CEO of Pfizer and Chair of the GLG Institute; Jake Sullivan, former Director of Policy Planning at the United States Department of State; and Michael Vickers, former U.S. Under Secretary of Defense for Intelligence; and Tom Wheeler, former FCC Chairman, among others.
About GLG / Gerson Lehrman Group
GLG is the world's leading membership for professional learning. Business leaders, investors, consultants, social entrepreneurs, and other top professionals rely on GLG to learn in short- and long-term engagements from more than 500,000 members and other experts. Clients partner with GLG to address their most complex strategic challenges, make better business decisions, and advance their careers through conversations, mentorships, small group meetings, surveys, and other interactions—all within a rigorous compliance framework. Headquartered in New York City, GLG's approximately 1,400 employees work from offices in 12 countries. For more information, visit www.GLG.it.


text:
// ------------------------------------------------------------
//  Copyright (c) Microsoft Corporation.  All rights reserved.
//  Licensed under the MIT License (MIT). See License.txt in the repo root for license information.
// ------------------------------------------------------------
using System;
using samples.iot.core;

namespace samples.iot.providers.sender
{
	/// <summary>
	/// Device sender factory.
	/// </summary>
	public class DeviceSenderFactory : IDeviceSenderFactory
	{
		/// <summary>
		/// Gets the sender based on protocol.
		/// </summary>
		/// <returns>The sender.</returns>
		public IDeviceSender GetSender()
		{
			// returning default implementation, can be changed to return specialized version
			return new DeviceSender();
		}
	}
}


text:
Q: Remove short title and author from the sidebar For my presentation, I am using Hannover theme. However, I'd like to change the contents of the sidebar. By default, the sidebar shows "short author" and short title in the upper left area. I would like to remove them, keeping in the sidebar only the sections and subsections titles.
Does anybody know how to do it?
This is the code I have:
\documentclass[11pt]{beamer}%blackandwhite
\usepackage[spanish,portuguese,english]{babel}
\usepackage{amsmath,amssymb,amsthm}
\usepackage[utf8]{inputenc}
\usepackage[T1]{fontenc}
\usepackage{graphicx}%gráficas
\usepackage{graphics}%gráficas
\usepackage{hyperref}%hypervinculo
%\usepackage{beamerarticle}
\usepackage{beamerprosper}
\usepackage{multicol}%varias columnas
\newtheorem*{ejem}{Ejemplo}
\newtheorem*{prop}{Proposición}
\newtheorem*{teor}{Teorema}
\newtheorem*{defin}{Definición}
\newtheorem*{lema}{Lema}
\newtheorem*{algoritmo}{Algoritmo}
\newtheorem*{cor}{Corolario}

 \mode<presentation> {
  \usetheme{Hannover}
  \usefonttheme{serif}
  \usecolortheme{beaver}
}
\setbeamercovered{dynamic}
%\logo{\includegraphics[height=1.5cm]{img.eps}}
\setbeamertemplate{enumerate items}[default]
\setbeamertemplate{theorems}[ams style]

\setbeamercolor{alerted text}{fg=blue}

%EDITION OF INFOLINES

\makeatletter
\setbeamertemplate{headline}{
    \leavevmode%
    \hbox{%
        \begin{beamercolorbox}[wd=\paperwidth,ht=2.75ex,dp=1ex,center]{author in head/foot}%
            \usebeamerfont{section in head/foot}%\insertsubsection\hspace*{2ex} esta linea sin el % produce la franja roja arriba
        \end{beamercolorbox}}
    }
    \setbeamertemplate{footline}{
        \leavevmode%
        \hbox{%
            \begin{beamercolorbox}[wd=.333333\paperwidth,ht=2.25ex,dp=1ex,center]{author in head/foot}%
                \usebeamerfont{title in head/foot}\insertshorttitle
            \end{beamercolorbox}%
            \begin{beamercolorbox}[wd=.333333\paperwidth,ht=2.25ex,dp=1ex,center]{title in head/foot}%
                \usebeamerfont{title in head/foot}\insertshortinstitute
            \end{beamercolorbox}%
            \begin{beamercolorbox}[wd=.333333\paperwidth,ht=2.25ex,dp=1ex,right]{date in head/foot}%
                \usebeamerfont{date in head/foot}\insertshortdate{}\hspace*{2em}
                \insertframenumber{} / \inserttotalframenumber\hspace*{2ex}
            \end{beamercolorbox}}%
            \vskip0pt%
        }
        \makeatother

%EDITION OF  SECCIONES Y SUBSECIONES IN THE SIDEBAR
\setbeamercolor{section in sidebar}{fg=black!90, bg=white}%color-sombra barra lateral
%\setbeamerfont{section in sidebar}{series=\bfseries}%letra barra lateral
\setbeamercolor{sidebar}{bg=gray!90}%color del fondo de la barra lateral
\setbeamerfont{sidebar}{family=\rmfamily\selectfont}
%\setbeamerfont{section in sidebar}{size=\fontsize{2}{4}\selectfont}
%\setbeamerfont{subsection in sidebar}{size=\fontsize{2}{4}\selectfont}
%\setbeamerfont{subsubsection in sidebar}{size=\fontsize{2}{4}\selectfont}
%\setbeamercolor{section in sidebar}{bg=white,fg=black!80}
%\setbeamercolor{subsection in sidebar}{bg=white,fg=black!50}

   \usefonttheme{serif}
   \useoutertheme{infolines}% numera las diapositivas
\setbeamertemplate{page number in head/foot}[totalframenumber]
\setbeamertemplate{navigation symbols}{\footnotesize\usebeamertemplate{page number in head/foot}}

\title[\textsc{aaa }]{\textrm{AAAAAAA}}
\author[\textsc{}bb]{\textsc{BBBBBS}}
\institute[]{ \textrm{uuul \\ UUUUU}\\ \vspace{0.3cm}}
\date{}

%\AtBeginSection[]{\frame{\frametitle{Index}\tableofcontents[current]}}

\begin{document}
%\bibliographystyle{amsplain}%Estilo de bibliografia
\frame{\titlepage}
%\part{Talk}
%\frame{\frametitle{Index}\tableofcontents[part=1]}

\section{}
% Slide 1
\begin{frame}{Contents}
    \begin{enumerate}[<+->]
        \item A
        \item Ac
    \end{enumerate}

\pause

\end{frame}
\part{Talk}
\section{Overview}
%Slide 2
\begin{frame}{Overview}
\end{frame}
\subsection{Introduction}
\begin{frame}
    asbdf
\end{frame}

\end{document}


text:
The characterization of Vibrio cholerae non-O1 strain causing perforative pan-peritonitis
Y. Ichinose, M. Ehara, T. Shimizu, T. Ohmagari, M. Kaku, K. Hara, T. Tsuji, T. Simada
MED - Medical Sciences
We report a case of a 53-year-old male with Vibrio cholerae non-O1 (serotype O19) infection, resulting in perforative pan-peritonitis. The patient had a history of gastric cancer and a gastrectomy was performed one year prior. The patient had previously been admitted with nausea and vomiting and was diagnosed with a sub-ileus condition. He was provisionally discharged when his condition improved and during that period he ate raw fish caught locally in Nagasaki Prefecture, and several hours later he experienced a sudden onset of severe abdominal pain and nausea and on diagnosis of pan-peritonitis an emergency resection of the transverse colon was performed. We subsequently isolated Vibrio cholerae non-O1 from the patient's peritoneal fluid and stool. He died of multiple organ failure three weeks later despite intensive chemotherapeutic care and treatment for shock and disseminated intravascular coagulation. The strain of Vibrio cholerae non-O1 isolated was non-toxigenic but hemolytic with hyper-producing of metalloprotease.
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
https://doi.org/10.11150/kansenshogakuzasshi1970.75.696
Published - 2001 Aug
10.11150/kansenshogakuzasshi1970.75.696
Dive into the research topics of 'The characterization of Vibrio cholerae non-O1 strain causing perforative pan-peritonitis'. Together they form a unique fingerprint.
Vibrio cholerae non-O1 Medicine & Life Sciences 100%
Peritonitis Medicine & Life Sciences 60%
Nausea Medicine & Life Sciences 34%
Transverse Colon Medicine & Life Sciences 24%
Ileus Medicine & Life Sciences 23%
Disseminated Intravascular Coagulation Medicine & Life Sciences 23%
Multiple Organ Failure Medicine & Life Sciences 22%
Ascitic Fluid Medicine & Life Sciences 22%
Ichinose, Y., Ehara, M., Shimizu, T., Ohmagari, T., Kaku, M., Hara, K., Tsuji, T., & Simada, T. (2001). The characterization of Vibrio cholerae non-O1 strain causing perforative pan-peritonitis. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 75(8), 696-702. https://doi.org/10.11150/kansenshogakuzasshi1970.75.696
The characterization of Vibrio cholerae non-O1 strain causing perforative pan-peritonitis. / Ichinose, Y.; Ehara, M.; Shimizu, T.; Ohmagari, T.; Kaku, M.; Hara, K.; Tsuji, T.; Simada, T.
In: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, Vol. 75, No. 8, 08.2001, p. 696-702.
Ichinose, Y, Ehara, M, Shimizu, T, Ohmagari, T, Kaku, M, Hara, K, Tsuji, T & Simada, T 2001, 'The characterization of Vibrio cholerae non-O1 strain causing perforative pan-peritonitis', Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, vol. 75, no. 8, pp. 696-702. https://doi.org/10.11150/kansenshogakuzasshi1970.75.696
Ichinose Y, Ehara M, Shimizu T, Ohmagari T, Kaku M, Hara K et al. The characterization of Vibrio cholerae non-O1 strain causing perforative pan-peritonitis. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 2001 Aug;75(8):696-702. https://doi.org/10.11150/kansenshogakuzasshi1970.75.696
Ichinose, Y. ; Ehara, M. ; Shimizu, T. ; Ohmagari, T. ; Kaku, M. ; Hara, K. ; Tsuji, T. ; Simada, T. / The characterization of Vibrio cholerae non-O1 strain causing perforative pan-peritonitis. In: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 2001 ; Vol. 75, No. 8. pp. 696-702.
@article{038defb820d64fe9a282c7e5ae7033b2,
title = "The characterization of Vibrio cholerae non-O1 strain causing perforative pan-peritonitis",
abstract = "We report a case of a 53-year-old male with Vibrio cholerae non-O1 (serotype O19) infection, resulting in perforative pan-peritonitis. The patient had a history of gastric cancer and a gastrectomy was performed one year prior. The patient had previously been admitted with nausea and vomiting and was diagnosed with a sub-ileus condition. He was provisionally discharged when his condition improved and during that period he ate raw fish caught locally in Nagasaki Prefecture, and several hours later he experienced a sudden onset of severe abdominal pain and nausea and on diagnosis of pan-peritonitis an emergency resection of the transverse colon was performed. We subsequently isolated Vibrio cholerae non-O1 from the patient's peritoneal fluid and stool. He died of multiple organ failure three weeks later despite intensive chemotherapeutic care and treatment for shock and disseminated intravascular coagulation. The strain of Vibrio cholerae non-O1 isolated was non-toxigenic but hemolytic with hyper-producing of metalloprotease.",
author = "Y. Ichinose and M. Ehara and T. Shimizu and T. Ohmagari and M. Kaku and K. Hara and T. Tsuji and T. Simada",
note = "Copyright: This record is sourced from MEDLINE{\textregistered}/PubMed{\textregistered}, a database of the U.S. National Library of Medicine",
doi = "10.11150/kansenshogakuzasshi1970.75.696",
journal = "Nippon Densenbyo Gakkai zasshi",
publisher = "Nihon Kansensho Gakkai",
T1 - The characterization of Vibrio cholerae non-O1 strain causing perforative pan-peritonitis
AU - Ichinose, Y.
AU - Ehara, M.
AU - Shimizu, T.
AU - Ohmagari, T.
AU - Kaku, M.
AU - Tsuji, T.
AU - Simada, T.
N1 - Copyright: This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
N2 - We report a case of a 53-year-old male with Vibrio cholerae non-O1 (serotype O19) infection, resulting in perforative pan-peritonitis. The patient had a history of gastric cancer and a gastrectomy was performed one year prior. The patient had previously been admitted with nausea and vomiting and was diagnosed with a sub-ileus condition. He was provisionally discharged when his condition improved and during that period he ate raw fish caught locally in Nagasaki Prefecture, and several hours later he experienced a sudden onset of severe abdominal pain and nausea and on diagnosis of pan-peritonitis an emergency resection of the transverse colon was performed. We subsequently isolated Vibrio cholerae non-O1 from the patient's peritoneal fluid and stool. He died of multiple organ failure three weeks later despite intensive chemotherapeutic care and treatment for shock and disseminated intravascular coagulation. The strain of Vibrio cholerae non-O1 isolated was non-toxigenic but hemolytic with hyper-producing of metalloprotease.
AB - We report a case of a 53-year-old male with Vibrio cholerae non-O1 (serotype O19) infection, resulting in perforative pan-peritonitis. The patient had a history of gastric cancer and a gastrectomy was performed one year prior. The patient had previously been admitted with nausea and vomiting and was diagnosed with a sub-ileus condition. He was provisionally discharged when his condition improved and during that period he ate raw fish caught locally in Nagasaki Prefecture, and several hours later he experienced a sudden onset of severe abdominal pain and nausea and on diagnosis of pan-peritonitis an emergency resection of the transverse colon was performed. We subsequently isolated Vibrio cholerae non-O1 from the patient's peritoneal fluid and stool. He died of multiple organ failure three weeks later despite intensive chemotherapeutic care and treatment for shock and disseminated intravascular coagulation. The strain of Vibrio cholerae non-O1 isolated was non-toxigenic but hemolytic with hyper-producing of metalloprotease.
U2 - 10.11150/kansenshogakuzasshi1970.75.696
DO - 10.11150/kansenshogakuzasshi1970.75.696
JO - Nippon Densenbyo Gakkai zasshi
JF - Nippon Densenbyo Gakkai zasshi


Last winter was one of the coldest experienced in Ireland in more than sixty years as subzero temperatures gripped the country for much of December and January. Temperatures were 2C lower than average.
Long-term forecaster Positive Weather Solutions has predicted a 'white-out' winter almost as harsh as the last with widespread snow, temperatures as low as -16C and transport chaos. Local authorities need to be warned that they'll have to handle another very cold winter. The prolonged cold spell last year put severe pressure on grit and salt supplies with some local authorities having to be resupplied with imported grit from the Continent.
The Sturdy Grit/Salt Bunker is ideal for storing grit or salt and is suitable for domestic or commercial use. Don't get caught out this year. A cold winter has already been predicted.


If you'd asked me a month ago about the chances of me running regularly and willingly, I would have scoffed and said that the likelihood of me going skydiving was much higher. Even after helping to launch ASICS's online training service, even after devouring Born to Run, even after attending Dr. 'Pose' Romanov's seminar… the idea of running held zero appeal for me. It was boring, it was slow, it was painful and it was just the least interesting way to get fit.
But now that I've put in a few 5+ km runs here and there as part of my triathlon training, I find myself… not minding it much. Even enjoying it sometimes.
that I caught myself wondering why I didn't do this more often. Oh yeah, I hate running! Or, maybe not?
So, today I did what any girl does when making a change. Get new shoes.
And… skydiving, huh? One day!


RHOC News: Briana Wolfsmith-Culberson Welcomes New Baby Boy!
Briana Wolfsmith-Culberson gave birth to her second child, a boy, today in Oklahoma.
Vicki shares that Briana's son weighed in at a healthy 7 lbs. 8 oz. and that Briana's family (her husband Ryan, mom Vicki, and Vicki's mother) were all present to welcome her baby joy, who name is not as yet given, into the world.
Briana and her husband Ryan Culberson are already parents to 22-month-old son Troy.
Shame on You! Teresa Giudice Using The Media To Garner Sympathy?