Cutting edge web development with latest technologies which enable customer satisfaction and create limitless possibilities.
Industry standard development for iOS and Android platform with high rate of successful business and revenue which create brand value.
We at Atharva System provide top-notch services that can turn your ideas into a practical solution. We are developing the most beautiful, innovative, and productive solution for your needs. Use our services to build a successful business and take over your competition.
We have proven track record for building success for our clients with long-term results. We deliver the best quality and high performance to ensure your project will be successful. Our experts will maximize the efficiency and growth of your business.
Creating an astonishing user experience, with unmatched quality services which Leeds to reaching success! Innovative, functional and effective services are our advantage, visible in all our projects.
We have the best and the most experienced developers with the highest rate of success, who are highly motivated and equipped with the best tools and technologies. We have the right ingredients for achieving your success.
The key for success is the communication. We communicate with our clients to understand their wishes and needs, and therefore we respond with perfect solution to achieve our common goal.
Besides being the most quality web development solution provider, we build close bond with our clients which contributes to achievea long-term successful result.
Our developers have years of experience in creating projects with highest level possible. We have the experts to build businesses and develop projects that our client needs.
We're very happy with the TickTock theme, that is pretty and has unique features in which make it unbeatable. The customer service from Atharva also has been awesome, beyond the expectations. We think all these things together, plus the OpenERP features, make the Odoo the best system in the industry.
We choose Atharva System first behalf of templating for Odoo Enterprise 11, and realised - we can do more with them. We did and the decision was right and made us happy.
Working with Atharva System has been an absolute pleasure. They are reliable, quick to comprehend complex functionality, and always deliver top quality work. Communication is great, they listen to my needs and regardless of the size of project, I always feel like an important customer, not just a number.
Atharva System is really having excellent skills in Mobile(iOS, Android) technologies. They delivered me what I expected on time. We are really happy with their work. Great people to work with.
Atharva System is the leading service provider in Ruby on Rails from India. They are very professional and understood my requirements very quickly. Projects are carried out quickly and we can make as much corrections as necessary. It's always a pleasure working together. I will work with them again.


We flew home overnight – and arrived today at RDU.
It was simply a wonderful trip – we learned a lot, we saw the UNC global health partnership in action and we got to know a bit about the people and history of Peru.
This entry was posted in Miscellaneous on August 13, 2009 by roperhealth.


text:
// This file was generated by Mendix Modeler.
//
// WARNING: Only the following code will be retained when actions are regenerated:
// - the import list
// - the code between BEGIN USER CODE and END USER CODE
// - the code between BEGIN EXTRA CODE and END EXTRA CODE
// Other code you write will be lost the next time you deploy the project.
// Special characters, e.g., é, ö, à, etc. are supported in comments.

package communitycommons.actions;

import com.mendix.systemwideinterfaces.core.IContext;
import com.mendix.webui.CustomJavaAction;
import communitycommons.DateTime;

/**
 * Converts a Unix timestamp to a dateTime object
 */
public class LongToDateTime extends CustomJavaAction<java.util.Date>
{
	private Long value;

	public LongToDateTime(IContext context, Long value)
	{
		super(context);
		this.value = value;
	}

	@Override
	public java.util.Date executeAction() throws Exception
	{
		// BEGIN USER CODE
		return DateTime.longToDateTime(value);
		// END USER CODE
	}

	/**
	 * Returns a string representation of this action
	 */
	@Override
	public String toString()
	{
		return "LongToDateTime";
	}

	// BEGIN EXTRA CODE
	// END EXTRA CODE
}

redpajama_set_name: RedPajamaGithub


Dublin : J. Duffy, 1854-1855.
Ireland > History > 19th century > Sources.
Ireland > Politics and government > 19th century.
by: Luby, Thomas Clarke, 1821-1901.
by: Cusack, Mary Francis, 1829-1899.
Daniel O'Connell upon American slavery with other Irish testimonies.
Swing and O'Connell a letter from Swing, the rick-burner, to Daniel O'Connell, M.P. on the late proclamations.
by: McGee, Thomas D'Arcy, 1825-1868.
by: O'Connell, Mary, d. 1836.


Rawhide Studio for that Unique gift !
Circle Dance Earrings! Wonderful movement and style.
57 days till…. You know what I'm talking about so I wont say it but Rawhide Studio's lightweight, natural rawhide jewelry makes a wonderful gift for any occasion. Purchase online, at one of our many fine outlets (look on our website for a full listing) or at one of these upcoming shows.
Last weekend we went to the Houston area for a family wedding. Saturday, the weather was fine and the wedding went off without a hitch! Congratulations to Anthony and Nicole Clarkson!
The day before the wedding we went into the big city ( Cheyenne is dinky in comparison) to visit the Houston Museum of Contemporary Craft and get some authentic Texas BBQ. First art then food!
HMCC is small but the shows were first rate. Two of the gallery spaces featured interesting ceramic shows and the third space had a book and jewelry show. In the center of the Museum is the Asher Gift Gallery. The Asher has been carrying Rawhide Studio jewelry for over a year now. The staff was very friendly and spoke well of our jewelry and its popularity. Thanks HMCC for supporting artisans around the country.
Drew's BBQ on Richmond and Roseland is the real deal. Locally owned with the man himself serving up the goods. Great brisket and sides!
When we say Rawhide Studio is Wyoming made we really mean it! Since the beginning we have tried to find a local source for our rawhide. When we searched the internet and came across Absaroka Western Designs in Dubois WY, we knew we had to make the 5 hour trek to see what the place had to offer. When we arrived at the shop we met the owner Joe Brandl and explained that we made jewelry out of rawhide and were looking for a Wyoming source. He took us through his workshop and then showed us some of his antelope and elk hides. We sorted through them, purchased a few and headed back to our campsite excited about our find! Of course the trip had to include some fishing for Dave and we made a connection with a gallery in Dubois called Pony Tracks. All and all a great trip to a beautiful part of Wyoming!
Dave and Georgia Rowswell invite the community to an open house and reception at Artful Hand Studio & Gallery. Open from 5-8pm on Friday May 2nd & Saturday May 3rd at 302 East 1st Ave. Cheyenne. Stop in and see what's new in the Rawhide Studio line and enjoy 25% off on our jewelry line and handmade paper cards. Think Mother's Day, graduation and wedding presents! Shop local and artisan made!
She's worked hard all her life so her hubby decided to splurge and buy her a pair of Prairie Pine earrings. As soon as the Prairie Pine necklace comes online he's going to buy that for her too! Then she can stop wearing that boring cameo brooch!
And the title and artist is?
Look Whose Wearing Rawhide Studio!
Sometimes you just have to have a little fun! Over the next three days I will be posting some famous folks who decided to be "Ahead of the Herd in Jewelry Style!" Here's the first. Can you name the artist?
Mona's looking fine in her violet Square Dance necklace from the Prairie Life collection!
We will have our line of jewelry at this unique venue's gift shop for the 2014 season! They also have handmade items made in Wyoming's state prison which gives the inmates some skills and spending money. We are looking forward to taking the tour of this historical site.
"The Wyoming Territorial Prison State Historic Site has an incredibly rich history. Run as a federal (territorial) and state prison from 1872 to 1903, it then became the Agricultural Experiment Station for the University of Wyoming after the State Prison relocated to Rawlins. The site is now operated as a Historic Site by the State of Wyoming".
Guided tours are provided on Fridays – Saturdays at 11:00 a.m. and 2:00 pm., Sundays – Mondays at 2:00 p.m. and are included in the price of admission.


The aim is to provide 120 women beneficiaries with the skills and knowledge of embroidery, sewing and finishing craftwork pieces so that they can produce final pieces that are both of quality and competitive. The knowledge on Palestinian embroidery (Tatreez) is informally passed from mother to daughter in the home: As it is a "verbal" passing of the Palestinian culture, some external patterns considered as traditional have been inserted. For this reason, it has been necessary to include training on Tatreez, its origins and patterns to familiarize the women beneficiaries with Palestinian embroidery origins and characteristics. This training not only provides them with knowledge of their own culture but also seeks to reinforce their self-confidence as they will be considered as craftswomen and transmitters of Palestinian culture instead of being considered as seamstresses. Likewise, Palestinian embroidery craftswomen do not generally know how to finish craftwork products, a situation which makes them dependent on organizations, enterprises and other actors that undertake the assembly of the final product. Training these women in the product finishing will allow them to be autonomous and control and work in the production process of the product from the beginning to the end. Therefore they can start up their own business without depending on other actors who increase the costs and reduce the benefits.
During six months, a first training phase of 15 women trainers will take place (4 from Rashidieh, 6 from Ein El Helwe and 5 from Beddawi/Naher El Bared according to the number of working woman in each camp and population). Subsequently, women trainers will teach the courses that they received to the rest of the 120 beneficiaries during 8 months with three days classes per week (5 hours daily) dedicating one day for embroidery of Tatreez (160 hours), one day for the creation of regional and international designs (160 hours) and a third day for training in commercialization, marketing and creation of small-sized enterprises with social character and good practices dissemination at workplace (160 hours).
Here, we try to use the bases established in the previous activity in terms of sewing and embroidery Tatreez to add in this activity art and market. Apart from the courses taught by Anat (following the same framework as described in the previous activity), the participation of Fundesarte is added here. The Spanish Foundation for Innovation of Craftwork (Fundesarte) is the public state entity in charge of the promotion of Spanish craftwork inside and outside national borders. It is a non-profit entity attached to the Ministry of Industry, Energy and Tourism whose main objective is to improve competitiveness in Spanish craftwork enterprises. Fundesarte works together with craftwork sector of various countries in developing projects by carrying out programs which target professionals of the sector and focus on the support and strengthening of its institutions, organizations and entities with the aim of benefitting from the sector in those countries in such a way that craftwork could be considered as an activity not only profitable but which improves the quality of life of those who earn their living with it.
The idea is to provide in this phase necessary tools to the 120 women beneficiaries so that they could (once the knowledge basis on Tatreez craftwork is established, and they are aware of the possible designs that can motivate these women in the creation of their own style and commercialization lines) obtain means to create their own business. To do so, key knowledge in terms of market study, legal support, business management and marketing skills will be provided. For greater efficacy, a project will be assigned to each group of women beneficiaries to stimulate their creation of a business that will be evaluated at the end of the project.
Creation of a cooperative of women with three headquarters, one in each camp (Rashidieh, Ein El Helwe and Beddawi/Naher El bared). The women will be trained for the creation, registration and manteinance of a cooperative in Lebanon. Due to the legal status of these working women, strong legal support and advise are necessary here which will allow the proper creation and registration of the cooperative before the Lebanese legal institutions. In order to do this we count with the technical assistance of a lawyer who carries out the complete legal registration of the cooperative with possibilities of sale abroad, and who guides and supports the women in the process and assists in possible legal requirements related with the constitution and the management of the cooperative.
An online shop will be openened from when the products are available.


See ale Coding Standard Guidelines.
Do NOT write CSS, write LESS!
Always write your code to a .less (or .sass) file and let Grunt compile it to a .css file and even a .min.css file.
Learn to use grunt in the background. It will automatically recompile your LESS to CSS when you make a change.
Every time you find identical LESS/CSS code in multiple files, or any time you want to copy/paste code to multiple files yourself, create a module!.
A module should be a file like /rsc/less/module_name.module.less.
Then, in each LESS file where you would have had duplicate code, add @import '.../module_name.module.less'.
Use _ (not -) in class names.
We do this because it makes it easier to double click a class name to select it entirely.
This also actually helps identifying bootstrap classes versus properietary classes.
When the core (or a widget, etc.) outputs a class="...", your class names should start with a very specific prefix like evo_.
For example you should use evo_username rather than username or evo_photo instead of photo.
This avoids conflicts with other things users may have in their skins.
Another example of a prefix is ufld_ which means "User field". The probability that this prefix is used by someone/something else on a page is very low.
Using poorly specific prefixes is nto a good idea. For example new_username or big_photo does not count as a prefix.
Class names without an evo_ or other very specific prefix should be used only in the LESS/CSS files of skins.
Any new classname added to the core must follow this rule. The reason why this rule is not enforced for existing class names is backward compatibility. If we change all existing class names suddenly, it will break many skins.
Use __ (double underscore) for modifier classes.
When equivalent, prefer margins to paddings.
Asymetric paddings are generally not cool. They make things ugly if we change the background color, for example on hover. Of course, you still need asymetric paddings if you need to compensate for an icon/glyph that is not well centered.


It has been over a year since our interview with metster, Cindy Barka. The members of Living with Metastatic Cancer in Canada refer to themselves as metsters or metavivors.
Last summer, the treatment Cindy was on for metastatic breast cancer stopped working. Her cancer had progressed. She was switched to a different medication to hopefully slow down the progression. With that come the inevitable side effects and applying for coverage for the new combination of drugs. Medications, especially for metastatic cancer, are expensive, very expensive.
When I checked in with Cindy in September, she was going through the difficult and painful adjustment, both physically and emotionally, to her new treatment protocol.
Cindy has written an open letter to any insurance company who will pay attention. This will give you an idea of her ongoing battle, not with the cancer, but with the insurance company.
I have metastatic breast cancer or MBC with bone metastasis. MBC has a 100% mortality rate. We, who have MBC, will never get better despite the fact that we may have outlived our original prognosis.
Every six months to a year, you send me Employee Status Report forms and Condition Impact Questionnaires to determine whether or not I am doing all that I can to improve my situation and to see if I am able to return to work, and most importantly, under the veiled threat of assessing my disability claim.
Throughout the years that I worked, my employer and I both paid into an insurance plan that included a long-term disability clause. That clause was negotiated by our union and is included to make sure that someone who is unable to work is not left destitute. Hence, the word "insurance".
While I understand the need to assess the merits of each case, as there are long-term disabilities that may improve with medical interventions and time, it is a proven fact that metastatic cancer is not one of those cases. Need I say once again, "metastatic cancer" is 100% fatal." It is a catastrophic disease and progressively gets worse.
Your questionnaires asking me what I do on a daily basis to improve my situation is completely offensive, like I have a choice as to whether or not I have a terminal illness, and that I have an option to make myself better and I may not be doing all that I can.
If I had a choice between this disease and returning to work, I can honestly say I would much rather be at work. I enjoyed my job, I enjoyed my co-workers. I would much rather be working towards retirement than trying to stave off progression and eventual death.
Whether I can bend, stand or vacuum for 10 minutes is irrelevant to my condition. "Please list or indicate all recreational activities or hobbies performed prior to your disability," is a slap in the face each time I have to fill out this form. It is a reminder of all the things that I have lost to this illness.
I know that the Pollyanna's of this world would look at it as an opportunity to see all the things that I can still do and on most days I would agree but when filling out these forms I experience PTSD like feelings or rather just PTSD. I get to review in detail all the things that I've lost and have my condition questioned by an outsider who could never hope to understand what it's like to live knowing that you are dying.
I once received a letter with the sentence "You have exceeded our life expectancy clause. Please have your doctor complete the attached forms". It took me a while to realize that you were actually asking why I wasn't dead yet as my original prognosis was 22 months.
Dear Insurance Company, I think it is definitely time that you update your forms and questionnaires to appreciate, and be more sensitive to, those with a terminal illness.
Cindy is now into her 8th year of living with metastatic breast cancer. As she mentioned in her letter, her initial prognosis was 22 months, less than 2 years, so she has filled out many Employee Status Report forms and Condition Impact Questionnaires. One would think after the first set of forms, corroborated by her oncologist, she would be able to simply live out her life without the threat of having her disability claim re-assessed. Instead of celebrating every half year or year that she continues to live and be a mom, daughter, sister, friend, she has to justify her existence.
We all pay into numerous insurance plans for most of our adult lives. We do this because "What if something happens?" We need to make sure we are covered so we don't have to worry, at least financially. But then the unthinkable happens and not only do we have to deal with the physical and emotional trauma, we have to battle the insurance company for the right to receive the benefits we are entitled to, the benefits we paid for.
It's time for insurance companies to change their ways and get out from behind their standardized forms and letters, their actuarial tables and charts, and move forward with a little empathy and compassion. That would, of course, require less emphasis on the bottom line and more focus on serving their clients.
Stay tuned next week to see Cindy's creative side, that is when she is not busy with treatments, appointments, and filling out insurance forms.
If you are a Canadian with metastatic cancer looking for peer support online in a safe environment that welcomes all genders and sexual orientation, please request to join this private group at Living with Metastatic Cancer in Canada. In Ottawa and other places across Canada, there are also in-person support groups which you can connect with via the online group.


Rafaelle's work explores the bridge between the heart and the mind via the voice.
Every day will take you deeper into the realm of your authentic self and bring you closer to the true expression of your soul.
Poolside cocktails and hammock time!
Because we don't heal alone.
We take care of you from landing to take off!
Our chef Noel thrives on making your stay a culinary experience!
His approach to wholesome cooking has your experience Salvadorian cuisine, with a twist!
Exclusive to our group during the retreat!
Yes it is safe to travel and explore with us.
Dispel this travel myths and come see for yourself why Mylène has settled there!
We will take good care of you from foot down to take off!
Rafaelle has a strong passion for the expression of the soul through sound and song, guiding people to their authentic voice, she helps liberate the constraints of the mind to where the heart song wants to emerge.
She inspires confidence and a soft strength in both the fire of creativity and the waters of deep inner connection.
Drawing from her manual therapy, restorative yoga and mindfulness practice, Mylène is known as a 'fascia whisperer' and soundboard for what one is looking to rewire, or repattern.
Her dedication to 'the art of being human' make for an inspiring presence, where people can dive deeply into their 'bigger life'.
*Airport transfer in only included when travelling on the exact days of the retreat.
** We are happy to coordinate transportation and hotels outside of the retreat dates. A $25 flat fee applies for all extra travel plans.
Send us your application and we will invoice you based on your selection upon reception of this form!
All prices are in US$. The amount will be transferred in CAD$ upon invoicing.
Who will you be traveling with for this retreat?


text:
Bob Marley Bio-Musical Set for Baltimore's Center Stage
Bob Marley performing during the 'Rastaman Vibration' Tour in London, UK (June 1976)
The Baltimore Center Stage will soon premiere their very own Bob Marley musical focused on the reggae icon's life between 1975 and the tail-end of 1977.
It will also include the assassination attempt and a self-imposed isolation in England when he recorded Exodus and Kaya.
Take a look at what playwright and enter Stage artistic director Kwame Kwei-Armah had to say about it below:
"Biopics and musicals that cover people's lives are invariably difficult. The attempt is to make this into the jukebox musical that doesn't smell of jukebox musical. The idea is to let it come out of the truth of the play."
The musical will feature a few crowd-pleasers such as "I Shot the Sheriff," "No Woman," "No Cry" as well as songs that appear on Exodus, Kaya and the other album he made in the show's time frame Rastaman Vibration.
Though not serving as producers, Marley family members are involved in the development and writing of the show, with his daughter Cedella Marley stating:
"When it comes to our father's work and legacy, we have always been mindful in selecting the artists with whom we choose to collaborate. We couldn't be more excited about the team that is assembled for this project."
[via billboard.com]
MusicTheatre
Baltimore Center StageBob MarleyKwame Kwei-Armahmusicalsreggaetheater
Teonny Spears
Pop culture extraordinaire, Mickey Mouse lover, Britney Spears fanatic, and occasional manipulative bitch from Louisiana. As a kid, I used to write short stories and draw pictures to go along with them, they were my escapes. I began blogging in 2005 on Myspace just to speak on certain celebrities and share my thoughts and in late 2008 early 2009 I started doing my own weekly BlogTV show called EnterSHADEment Talk, which ended in late 2012. Between the show, I was appearing on various podcasts and writing for the now defunct DefGlam. I just want to inform people about their favorite celebrities or actors, not for fame, not for attention, but because I generally love it. I enjoy all music but mostly pop. I'm into fashion. Rihanna is that bitch and MGK is underrated.
ICYMI: John Legend's Marvin Gaye Tribute to Stream Through Thurs. Night
Watch: Grey's Anatomy's Jesse Williams Blasts CNN for Propaganda in Michael Brown Case

redpajama_set_name: RedPajamaCommonCrawl


text:
Twelve giants of Plymouth we lost in 2020
These local heroes are sorely missed
Molly DowrickSenior Reporter
Get the latest nostalgia features and photo stories straight to your inbox
Plymouth mourned the loss of some truly incredible people last year.
From community champions that volunteered hours and hours for charity, to local legends that cheered people up and made everyone smile, we sadly lost some real Plymouth heroes in 2020.
We'd like to honour them by remembering them and sharing what they did for Plymouth.
If you'd also like to pay tribute to them, feel free to leave a tribute message in the comments section.
Live updates from your postcode area
Crime logs
Steve Whiteway, businessman and community hero
Bravery - Steve with his son and daughter Lucy (Image: William Telford)
One of Plymouth's most respected businessmen, Steve Whiteway, sadly died last October, just one day after a train was named in his honour for services to the city. He was just 61.
Mr Whiteway had spent over 50 years volunteering and serving the Plymouth community and had raised more than £750,000 for charity during his lifetime.
He was a director of Devon and Plymouth Chamber of Commerce and had dedicated his life to helping others - so it was no surprise that hundreds of people shared tributes to him after hearing of his passing.
One PlymouthLive reader, Sarah Parson wrote: "You did so much for the Plymouth community. We loved our coffee catch ups with you. I'm glad I got to meet you. Always smiling and made time for us.
"A lovely gentleman with a kind heart. You will be missed."
Another reader, Annemarie Kerr added: "So so sad to hear. You were one in a million. Keep on playing with the great musicians in the sky. Big hugs to all your family. Steve you done Plymouth proud."
Mr Whiteway was born and raised in Stonehouse and his first job was selling pianos in a music shop.
He always loved music and was a familiar sight at concerts across the city, while also working hard in business, banking and marketing.
Among his long list of awards and accolades, Mr Whiteway was awarded the Prime Minister's Points of Light Award by then Prime Minister Theresa May for his work in helping alleviate food poverty in Plymouth.
He also won the Lifetime Achievement Award at the South West and Business Community Awards in Swindon in 2020, three years after receiving the Lifetime Achievement honour at PlymouthLive's community awards.
At the time, he said: "I have worked with over 160 charities over the years, by raising profiles through music and sport."
Connal Cather, hospital radio volunteer
Connal Cather was a community radio legend (Image: Hospital Radio Plymouth)
Local legend Connal Cather, who joined the Hospital Radio Plymouth team in the 1970s and had been involved ever since, sadly passed away in November at the age of 97.
Mr Cather was well known for his 'Nostalgic Time' radio show, which played hits from the 1920s, 1930s and 1940s, and in 2008 was the recipient of the 'John Whitney Award' from the hospital's Broadcasting Association, praising him as an 'individual who has demonstrated an outstanding contribution to hospital radio over a period of years'.
Hospital Radio station manager, Keith Jolley said: "Connal was a true legend.
"Over the years, many new members started out as a production assistant on his show.
"Although dealing with music made way before they were born and which they were unfamiliar with, they came to enjoy the music and the warm style of Connal's presentation."
Hospital Radio Plymouth president Andrew Hill, who delivered the eulogy at Connal's funeral, added: "Connal's dedication to hospital radio and his enthusiasm for his programmes was remarkable. He was an inspiration to us all.
"We shall be forever grateful for the chance meeting he had in a pub on the Barbican with station founder Jimmie Constable in 1970, which was the catalyst for him taking up such an enduring involvement with hospital radio and presenting programmes enjoyed by so many over the decades."
Ruby Smith, 'Plymouth's number one ice cream lady'
Ruby and Jon ran 'Jon Jon & Ruby' on Plymouth Hoe for several years (Image: Danielle Smith)
Local legend Ruby Smith of popular independent ice-cream business 'Jon Jon and Ruby' sadly passed away in December.
Ruby had been serving ice-cream and tasty treats on Plymouth Hoe for over 30 years and many locals saw her as 'Plymouth's number one ice cream lady'.
Ruby, who grew up in North Prospect, always loved Plymouth and its people and was well-known across the city for her kindness and generosity.
"She would always go out of her way for anybody, and always do everything and anything for anyone," Ruby's granddaughter Danielle Smith said, "she was my absolute world, and life without her will never be the same."
Ruby first launched her ice-cream business with her late husband Jon, known as 'Jon Jon,' over 30 years ago.
The pair ran 'Jon Jon and Ruby' together for several years - and were widely considered two of Plymouth's biggest "ice cream legends" and even inspired other local businesspeople to get into the ice-cream industry.
When Jon passed away in 2008 Ruby's mother-in-law Edna, known by many as 'Polly,' joined the business to keep it going with Ruby.
She was "well known and loved" by many people across the city, her family say, and will be greatly missed.
Paying tribute to her Nan, Ruby's granddaughter Danielle said: "Nan was so well-known and loved by so many people in Plymouth.
"She would always go out of her way for anybody, and always do everything and anything for anyone.
"She was a kind, beautiful, heart-warming person, and she will be greatly missed by many of people. But she will never be forgotten."
Joe Pengelly, BBC Spotlight newsreader
Joe Pengelly worked for the BBC in the 60s and 70s (Image: Archive image)
Popular BBC Spotlight newsreader Joe Pengelly sadly passed away in September at the age of 96.
Mr Pengelly was a favourite on the small screen throughout the 1960s and 1970s and also helped launch one of the first weekly radio shows on Hospital Radio Plymouth.
He served in Italy and Austria during World War Two and studied History at Jesus College, University of Oxford in the 1940s, but was mostly known in Plymouth and the surrounding areas for his work for the BBC.
Mr Pengelly's son, also named Joe Pengelly, said: "After his degree at Oxford, Joe joined the family business and was a director, until the family business, which had shops in Plymouth and all over Cornwall, was sold in the late 1960s.
"The lure of television broadcasting took hold and until retirement in 1979 Joe worked at BBC Plymouth as a continuity announcer and newsreader both on television and radio.
"As a young child I remember my father taking part in an air sea rescue for the cameras – how he managed it I have no idea since he was not the best of swimmers.
"He loved the atmosphere at the BBC and connecting with local people.
"People will remember him as someone who always had an interest in them and what they did."
Mr Pengelly was married to wife Barbara for 55 years before her death in 2010 and leaves behind his son, Joe, daughter-in-law Janet and four grandchildren, Sam, Joe, Phoebe and Verity.
Des O'Leary, grassroots football hero
Tributes flooded in for Des O'Leary last March (Image: Tony Carney)
Plymouth football legend Des O'Leary sadly passed away in March 2020, just three months after being diagnosed with terminal lung cancer. He was just 70.
Mr O'Leary was well-known across the South West for his huge contribution to grassroots football in the region and his tireless service managing multiple community sporting events in Plymouth.
He was also the popular president of Devon Junior and Minor League (DJM) and organised the annual DJM League Presentation Night at Plymouth Pavilions, which typically saw over 2,000 people attend.
Chairman of the DJM, Dave Keast told PlymouthLive last year: "Des informed us in December that he had been diagnosed with lung cancer and was very philosophical about it and did not want anyone to make a fuss.
"He told us in case he could not attend any meetings and just carried on with his DJM work. Even when he was in hospital he was still organising things and making sure we carried out instructions.
"Those clubs lucky enough to have won trophies and attended the annual presentation evenings at the Pavilions will know how much work goes into making them such a success.
"Des was the one who orchestrated things from beginning to end, organising the trophies and collecting, storing and cleaning them, and making sure they were all in place on the day, making sure all the recipients had their tickets and additional trophies. He also had the knack to make sure that his willing band of helpers were in place.
"We will always remember him as a colleague but mainly as a good friend who would do anything for anyone."
Chairman of the Devon Football Association (FA) and president of the DJM, Bernard Leach added: "Des was a fantastic servant to football in Plymouth, a massive character and a total gentleman.
"In addition to all the jobs he did for the DJM, Des volunteered to be an independent member for the County Disciplinary Commission and became a valued member, providing a humour to the occasion that only Des could. The accused people left with their suspension, but were smiling at the way it was done.
"He will certainly be missed in Devon football."
Mick McDonnell, popular publican and national coordinator of 'Best Bar None'
Mick McDonnell pictured outside the Mount Pleasant pub with barman Matt Baker in 2010
Former landlord of the Mount Pleasant pub and popular Plymouth man Mick McDonnell sadly passed away in March 2020 at the age of 59.
Well-known and respected across the city as the manager of several of Plymouth's most famous pubs, Mr McDonnell was also the national coordinator for the UK's 'Best Bar None' ('BBN') accreditation scheme, a Home Office supported scheme which aims to improve standards in the evening and night time economy.
Mr McDonnell founded Plymouth's BBN scheme and regularly travelled across the UK to attend meetings with police chiefs and government ministers, and dedicated much of his time to helping managers at pubs and clubs across the UK introduce a variety of measures to help keep their venues safe for customers and staff.
Mr McDonnell unfortunately had to stand down from the job he loved when he was diagnosed with bowel, liver and lung cancer in November 2019.
After a brave fight against the disease, he died peacefully at home in Plymouth surrounded by his family in March 2020.
His daughter Nadine McDonnell led tributes to her father and described him as "huge personality" who was "loved and respected in equal measure by family, friends and colleagues alike".
Patricia Wake MBE, foster mother to over 400 children
The late Gerald and Patricia Wake with their MBEs (Image: Guy Channing)
A Plymouth great-grandmother who transformed the lives of hundreds of Plymouth youngsters sadly died last April at the age of 89.
Patricia Wake and her late husband Gerald spent over 40 years supporting young people in the city and fostered more than 400 children over the years, while also raising their own six children.
Back in 1998, Mrs Wake told PlymouthLive's sister newspaper the Western Morning News: "We fostered five to start with, although you aren't allowed now to look after more than three at the same time.
"We just love children and it was wonderful to be able to do something to help them live happy contented lives, which is what has happened in many cases.'"
Tributes poured in for Mrs Wake, with many mentioning how she was "full of love" and made a positive impact on the youngsters she fostered.
One tribute said: "Was lucky enough to be fostered by Gerald and Pat and their wonderful family. Thank you. You restored my faith in human nature. RIP."
Another said: "A very wonderful lady is joining the angels up above, Pat you were one of a kind, always full of love, thank you for tea and toast, wish i had the chance to try your roast. Reunited with Gerald again, gone are the suffering and pain, Pat you have a heart of gold and in heaven it will never grow old. RIP"
Howell Phillips, secondary school teacher and rugby coach
Howell Phillips coached rugby to students at St.Boniface College
Welsh rugby legend Howell Phillips, who taught PE at St Boniface's Catholic College in Plymouth for 37 years, sadly died in October at the age of 69.
Howell moved to Plymouth in 1973 and studied at the College of St Mark and St John (now Plymouth Marjon University) and soon became a key player and coach on the rugby field.
Over the years he coached a number of clubs in the city, including Plymouth Albion u15s, Plymouth Argaum and Plympton Victoria and also spent 37 years teaching PE at St Boniface's College, predominantly coaching rugby and basketball.
After being diagnosed with cancer in 2016, Mr Phillips and his family continued to live life as normal - attending rugby matches, playing with a ukulele band and taking trips back to native Wales.
After his passing, PlymouthLive received dozens of thoughtful tribute messages from locals who had been taught by Howell at St Boniface's and those who were lucky enough to be coached by him.
Howell's son Rhys announced his passing on Facebook, he said: "It is with a heavy heart we announce that last night [October 1] Dad/ Howell passed away.
"A truly remarkable man, to say he fought a battle is an understatement. An amazing husband, total hero of a dad and a doting Grancha, he will be missed terribly by so many. A true Welsh legend Caru ti Dad x"
A former student at St Boniface College, Plymouth Albion and Exeter Chiefs player Luke Arscott said: "What an absolute gent, never let you get too big for your boots."
Former Plymouth Albion player and former St Boniface College student Jack Arnott added: "Howell Phillips. More than just a teacher... a mentor, an inspiration and summed up, a legend. A huge influence to me in my school days. This man will be sorely missed by many people, it was a privilege to have known him."
Jim Webster, head of crime and chief superintendent in Plymouth
Chief Supt Jim Webster sadly died last year [2008 picture] (Image: Lucy Blake)
Plymouth's 'former top cop' died unexpectedly at the age of just 59 last April.
Mr Jim Webster was a former acting assistant chief constable and had served within Devon and Cornwall Police for a number of years, including as head of crime and chief superintendent in Plymouth.
His passing shocked colleagues across the region.
At the time, Devon and Cornwall Police Chief Constable Shaun Sawyer said: "We have today been made aware of the sudden death in north Cornwall of an individual who we believe to be Jim Connelly-Webster.
"Jim was a former acting assistant chief constable and had served within Devon and Cornwall Police, including as head of crime and chief superintendent in Plymouth, where he was commander in the city for a number of years. Jim finished his career in the Metropolitan Police as commander before coming back to the South West.
"Jim was extremely well known, respected and liked by colleagues and partners across the force, especially in Plymouth. His untimely death is a shock to us all.
"Our condolences go to all of his family, loved ones and friends at this sad time."
Mr Webster was born in Plymouth and grew up in the Millbridge area, before moving to London when he was 18.
In 1980 he joined the Metropolitan Police, serving in the CID for most of his career.
While there he was responsible for Project Sapphire, which led to improvements in the way rape victims are treated by the police, and investigated many serious rapes, including the notorious 'Beast of Belgravia' case. He also worked for the Regional Crime Squad investigating international drug-related crime, including 'Yardie' gangland murder and drug networks.
In 2003, after cutting crime rates by more than half in the borough of Lambeth, he returned to the South West where he took up the role of detective chief inspector with Devon and Cornwall Police, working at the force headquarters in Exeter.
He later took up the post of chief superintendent of Plymouth in 2007 and helped reduce violent crime in the city while improving residents' quality of life - you can read more about his work in the city here.
Maureen Porter, community hero
Maureen was involved in missionary work in Brazil for many years
Hoards of people lined the streets of Mutley holding purple balloons last September, after adored Plymouth woman and community hero Maureen Porter made her final journey through Plymouth.
Incredible Ms Porter had served communities in Plymouth for over 20 years, before sadly being diagnosed with pancreatic cancer in early 2020.
Ms Porter sadly lost her arm in an elevator accident when she was young, and was told she was never going to be able to do certain things.
But she exceeded all expectations and became one of the first women to waterski one-handed and also trained as a dental nurse.
She worked as a missionary in the Amazon rainforest for over 30 years and co-founded PEPE international, a play group which taught children how to clean their teeth, read and write.
She also set up toddler group Buzzy Bees at Mutley Baptist Church and was an active member of the Mutley community.
People lined the streets donning purple clothes and balloons
On the day of her funeral, people lined the streets holding purple balloons in her honour.
Ms Porter's daughter, Rachel Pealing, said purple was her favourite colour and was also fitting for the tributes as the symbol of pancreatic cancer was a purple pansy.
She said: "Purple was her favourite colour. If you looked in her wardrobe she was always wearing purple. And she discovered when she had pancreatic cancer that the purple pansy is the logo or the symbol of pancreatic cancer so she embraced the purple even more.
"Everyone wore purple to give her the send off, she wouldn't have wanted people to be sad.
"She knew where she was going, she wanted everyone to be happy for her and make as much noise as they can because it's what she would've wanted.
"The funeral director said he'd never seen a funeral like it. People were just lining the streets. There was also a group at Emmanuel Church too!
"It was very emotional and just to see how much everyone else loves her was just so heartwarming.
"It was so nice to see the people who didn't know her coming out of the shops and clapping as well. The community spirit was there."
Scott Prideaux, campaigner
Scott Prideaux was the man responsible for getting Plymouth's landmarks to glow purple (Image: Penny Cross / Plymouth Live)
A Plymouth legend who was one of the driving forces behind getting Plymouth landmarks illuminated for pancreatic cancer awareness sadly died last year..
Scott Prideaux was diagnosed with inoperable pancreatic cancer in 2017 but still continued to live life with positivity and dedicated much of his time to raising awareness of the disease and volunteering for charity.
His daughters shared a beautiful tribute to their "wonderful" dad on social media shortly after his death last June.
They said: "It's with a broken heart we tell you that Scott passed away early this morning. He was comfortable and surrounded by love.
"Dad was the most incredible man, and we feel so very lucky to have had him in our lives. Dad brought joy to everyone who met him, and he will be missed terribly.
"Thank you to all the friends and family who were part of his life. We hope you remember him as the life and soul of every party."
Gipsy Acora, local legend and fortune teller
Gipsy Acora was told he had the "gift" by his grandmother who raised him
It was a very sad day when news broke that local legend David Broadway, known by many as 'Gipsy Acora,' had passed away in November after a long illness.
Back in 2018, Mr Acora told PlymouthLive his grandmother used to take him out walking and would often tell him he "had the gift".
He said: "Very often when we were out walking I'd stop and say gran can I have an ice cream?
"We were in the middle of nowhere and she'd say what do you mean, we're out in the sticks, where are you going to get ice cream from?
"I'd say there's a beauty spot about ten minutes from here and there's an old ice cream van there, and she'd say ok if there's one there I'll get you one, and sure enough we'd go down and there would be an ice cream van there.
"She's say to me oh dawdy dawdy, you've definitely got the gift, when you get older you'll definitely be using this gift. She could tell I had it, when I was very very young.
"It turned out everything she said come right, weird."
Over his 50 year career, well-loved Gipsy read fortunes at his venue on the Barbican to thousands of people, including some of television biggest stars, such as presenter Phillip Schofield and actor Steve McFadden.
On the day of his funeral, dozens of people lined Southside Street to pay their respects as his hearse drove past.
Sammie Radley, Gipsy's daughter, said she believed her dad "just gave up," when her mum Jeanette sadly lost her battle with cancer during the first lockdown.
But he kept telling fortunes "until the very end" and worked every Friday and Saturday, when lockdown restrictions allowed.
He will be sorely missed.


The People Radar | OhGizmo!
By David Ponce on 10/11/05 • Leave a comment!
You gotta love it when gadgets actually have the potential to save lives. Take this wonderful new product from Japanese firm Oyo. It's a handheld "radar" that's used to locate people that are alive, but immobile, trapped under rubble.
The system can pinpoint the location and the depth of persons who are breathing by detecting the electromagnetic waves that reflect back from their moving chests.
To use the system, wireless antennas are placed at the search site to send out signals and capture the signals that reflect back. This information is relayed to the handheld radar reader, which analyzes the data and displays moving objects as black dots and living but immobile persons as red dots. Each antenna can search an area of 1 square meter to a depth of around 4.5 meters. A single radar analyzer can read the signals from as many as 30 antennas.
It will be launched this month, and hopefully emergency rescue teams worldwide will buy into them.


Student Ambassadors are a small group of student leaders (10th, 11th and 12th graders) dedicated to the positive promotion of Holy Family Cristo Rey Catholic High School. They exhibit academic excellence and a strong commitment to community service. The Student Ambassadors serve as front line representatives of Holy Family Cristo Rey to prospective families, specifically prospective students. They will work on a volunteer basis.
Student Ambassadors are visible at many campus events held for prospective students and families and in conjunction with other organizations on campus when necessary. Student Ambassadors have the unique opportunity to develop and receive training in communication, public relations, marketing and interpersonal skills.
Student Ambassadors serve as an essential component to promoting the Holy Family Cristo Rey's mission. Several responsibilities are placed on the Student Ambassador.
 To remain in an active Student Ambassador you must attend ALL meetings and 1 training session, actively participate in volunteer offerings, and conduct ALL ambassador actions in a professional manner. Failure to do so, results in immediate disqualification of position by the Admissions/Corporate Internship staff.


text:
Abraham HaKohen of Kalisk (1741–1810) was a prominent Chassidic rabbi of the 3rd generation of Chassidic leaders. He was a disciple of Dov Ber of Mezeritch.

Biography
Avraham was born in 1741 in Kalyshki, Belarus to Alexander. In his youth, Abraham Kalisker studied Torah with the Vilna Gaon, who later became the leader of the mitnagdim - i.e. those who opposed Hasidic Judaism.

Kalisker and his followers took an emotional and mystical approach towards the service of God in contrast to the formalism of traditional religious scholars, who focused on Talmudic study. After the death in 1772 of his teacher, Dov Ber Mezeritch, most of the opposition to hasidism was directed against Kalisker and his disciples.

In 1777, at about age 36, he joined the first hasidic aliyah under the leadership of Menachem Mendel of Vitebsk and emigrated to the Holy Land. He died in Tiberias on 9 January 1810.

References

1741 births
1810 deaths
Hasidic rebbes
18th-century rabbis from the Russian Empire
Emigrants from the Russian Empire to the Ottoman Empire
Kohanim writers of Rabbinic literature
Burials at the Old Jewish Cemetery, Tiberias
People from Liozna District

redpajama_set_name: RedPajamaWikipedia


Comments: Hello, I have a question about standardization of OPC. You say that you do not claim an actual "OPC" level, oligomeric proanthocyanidins, because there is no current laboratory methodology to measure such chemicals. However, virtually every other reputable company lists their OPC, and guidelines suggest to look for a product that is standardized at 40 to 80 percent proanthocyanidins for best protective value, which you say can't be done. Could you please explain?
As stated on the website — You cannot measure oligomeric proanthocyanidins (in Grape Seed Extract). However, you can analyze the index value of proanthocyanidins in a sample of GSE versus another and get a relative strength of Brand"A" versus Brand "B".
We have been in the health food industry for 20 years, (in business for 32). This is not the first instance of companies putting up numbers on their labels to make their products look more potent than the competitors on the shelf. This happened with shark cartilage our first product (mucopolysaccarides), olive leaf extract (oleuropein), tomato (lycopene %), and now the Extra Virgin Olive Oil (the extra virgin part).
Did you ever wonder how when a product gets popular, that there are suddenly 100 different brands with that product under their labels claiming to be manufacturers? When we started processing the GSE in 1997 there were only 3 or 4 other actual producers of it in the U.S. I would be willing to bet you that this number has not changed much. We used to sell the GSE powder in bulk to a number of these other brands at the very beginning before deciding to cut them all off and sell it under our own label.
Unfortunately the U.S. health food industry is composed primarily of companies that are just labels who source out their raw material from suppliers, mainly overseas brokers and unfortunately now mostly from China. The only thing a lot of these companies actually process is the artwork on their labels and the invoices mailed with their orders. The only way to differentiate themselves from their competitors is to copycat the other labels and make their numbers for the supposedly active ingredient appear to be higher than the other companies.
So while you are on a mission to find the highest OPC level and best GSE for yourself, I would suggest that you also ask each of the companies you contact whether they purchase or actually produce their own product. We no longer even try to compare Seagate's GSE to any other brand since we no longer supply them with the powder, and these brands tend to jump around and seek out suppliers with availability and lowest cost. It would be like comparing a product we took the time and energy to build a factory and install machinery to create .. with some company's latest purchase from their raw materials broker.
Thank you for your inquiry. I realize this does not exactly answer your question. However, it is also impossible to prove a negative.
Sorry for all the text in this posting. The fish picture this week was taken of a couple of Guelly Jacks swimming in the center of the volcanic bay in Santorini. There were no other fish. The Greeks had eaten everything.


text:
FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome
H. Dai, V. W. Zhang, A. W. El-Hattab, C. Ficicioglu, M. Shinawi, M. Lines, A. Schulze, M. McNutt, G. Gotway, X. Tian, S. Chen, J. Wang, W. J. Craigen, L. J. Wong
Division of Genetics and Genomic Medicine
Mutations in FBXL4 have recently been recognized to cause a mitochondrial disorder, with clinical features including early onset lactic acidosis, hypotonia, and developmental delay. FBXL4 sequence analysis was performed in 808 subjects suspected to have a mitochondrial disorder. In addition, 28 samples from patients with early onset of lactic acidosis, but without identifiable mutations in 192 genes known to cause mitochondrial diseases, were examined for FBXL4 mutations. Definitive diagnosis was made in 10 new subjects with a total of 7 novel deleterious variants; 5 null and 2 missense substitutions. All patients exhibited congenital lactic acidemia, most of them with severe encephalopathic presentation, and global developmental delay. Overall, FBXL4 defects account for at least 0.7% (6 out of 808) of subjects suspected to have a mitochondrial disorder, and as high as 14.3% (4 out of 28) in young children with congenital lactic acidosis and clinical features of mitochondrial disease. Including FBLX4 in the mitochondrial diseases panel should be particularly important for patients with congenital lactic acidosis.
https://doi.org/10.1111/cge.12894
FBXL4 mutations
congenital lactic acidemia
early onset encephalopathy
mitochondrial disorders
10.1111/cge.12894
Dive into the research topics of 'FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome'. Together they form a unique fingerprint.
Mitochondrial Diseases Medicine & Life Sciences 100%
Mitochondrial DNA Medicine & Life Sciences 84%
Milk Medicine & Life Sciences 74%
Lactic Acidosis Medicine & Life Sciences 68%
Muscle Hypotonia Medicine & Life Sciences 16%
Sequence Analysis Medicine & Life Sciences 12%
Dai, H., Zhang, V. W., El-Hattab, A. W., Ficicioglu, C., Shinawi, M., Lines, M., Schulze, A., McNutt, M., Gotway, G., Tian, X., Chen, S., Wang, J., Craigen, W. J., & Wong, L. J. (2017). FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome. Clinical Genetics, 91(4), 634-639. https://doi.org/10.1111/cge.12894
Dai, H. ; Zhang, V. W. ; El-Hattab, A. W. et al. / FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome. In: Clinical Genetics. 2017 ; Vol. 91, No. 4. pp. 634-639.
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title = "FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome",
abstract = "Mutations in FBXL4 have recently been recognized to cause a mitochondrial disorder, with clinical features including early onset lactic acidosis, hypotonia, and developmental delay. FBXL4 sequence analysis was performed in 808 subjects suspected to have a mitochondrial disorder. In addition, 28 samples from patients with early onset of lactic acidosis, but without identifiable mutations in 192 genes known to cause mitochondrial diseases, were examined for FBXL4 mutations. Definitive diagnosis was made in 10 new subjects with a total of 7 novel deleterious variants; 5 null and 2 missense substitutions. All patients exhibited congenital lactic acidemia, most of them with severe encephalopathic presentation, and global developmental delay. Overall, FBXL4 defects account for at least 0.7% (6 out of 808) of subjects suspected to have a mitochondrial disorder, and as high as 14.3% (4 out of 28) in young children with congenital lactic acidosis and clinical features of mitochondrial disease. Including FBLX4 in the mitochondrial diseases panel should be particularly important for patients with congenital lactic acidosis.",
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author = "H. Dai and Zhang, {V. W.} and El-Hattab, {A. W.} and C. Ficicioglu and M. Shinawi and M. Lines and A. Schulze and M. McNutt and G. Gotway and X. Tian and S. Chen and J. Wang and Craigen, {W. J.} and Wong, {L. J.}",
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Dai, H, Zhang, VW, El-Hattab, AW, Ficicioglu, C, Shinawi, M, Lines, M, Schulze, A, McNutt, M, Gotway, G, Tian, X, Chen, S, Wang, J, Craigen, WJ & Wong, LJ 2017, 'FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome', Clinical Genetics, vol. 91, no. 4, pp. 634-639. https://doi.org/10.1111/cge.12894
FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome. / Dai, H.; Zhang, V. W.; El-Hattab, A. W. et al.
In: Clinical Genetics, Vol. 91, No. 4, 01.04.2017, p. 634-639.
T1 - FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome
AU - Dai, H.
AU - Zhang, V. W.
AU - El-Hattab, A. W.
AU - Ficicioglu, C.
AU - Shinawi, M.
AU - Lines, M.
AU - Schulze, A.
AU - McNutt, M.
AU - Gotway, G.
AU - Tian, X.
AU - Chen, S.
AU - Wang, J.
AU - Craigen, W. J.
AU - Wong, L. J.
N1 - Publisher Copyright: © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
N2 - Mutations in FBXL4 have recently been recognized to cause a mitochondrial disorder, with clinical features including early onset lactic acidosis, hypotonia, and developmental delay. FBXL4 sequence analysis was performed in 808 subjects suspected to have a mitochondrial disorder. In addition, 28 samples from patients with early onset of lactic acidosis, but without identifiable mutations in 192 genes known to cause mitochondrial diseases, were examined for FBXL4 mutations. Definitive diagnosis was made in 10 new subjects with a total of 7 novel deleterious variants; 5 null and 2 missense substitutions. All patients exhibited congenital lactic acidemia, most of them with severe encephalopathic presentation, and global developmental delay. Overall, FBXL4 defects account for at least 0.7% (6 out of 808) of subjects suspected to have a mitochondrial disorder, and as high as 14.3% (4 out of 28) in young children with congenital lactic acidosis and clinical features of mitochondrial disease. Including FBLX4 in the mitochondrial diseases panel should be particularly important for patients with congenital lactic acidosis.
AB - Mutations in FBXL4 have recently been recognized to cause a mitochondrial disorder, with clinical features including early onset lactic acidosis, hypotonia, and developmental delay. FBXL4 sequence analysis was performed in 808 subjects suspected to have a mitochondrial disorder. In addition, 28 samples from patients with early onset of lactic acidosis, but without identifiable mutations in 192 genes known to cause mitochondrial diseases, were examined for FBXL4 mutations. Definitive diagnosis was made in 10 new subjects with a total of 7 novel deleterious variants; 5 null and 2 missense substitutions. All patients exhibited congenital lactic acidemia, most of them with severe encephalopathic presentation, and global developmental delay. Overall, FBXL4 defects account for at least 0.7% (6 out of 808) of subjects suspected to have a mitochondrial disorder, and as high as 14.3% (4 out of 28) in young children with congenital lactic acidosis and clinical features of mitochondrial disease. Including FBLX4 in the mitochondrial diseases panel should be particularly important for patients with congenital lactic acidosis.
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KW - early onset encephalopathy
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JF - Clinical Genetics
Dai H, Zhang VW, El-Hattab AW, Ficicioglu C, Shinawi M, Lines M et al. FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome. Clinical Genetics. 2017 Apr 1;91(4):634-639. doi: 10.1111/cge.12894


text:
Ascolto dei passeggeri - Smiles
Scan & Fly
Logiscan compact
Assistenza ai passeggeri sordi – Servizio Tellis
Tracking wifi
Air quality biomonitoring
Integration of bike paths
Transition to electric vehicles
Planting a forest area
Air Side North Photovoltaic Plant
Quality and Integrated policy
Integrated policy
The circular economy project launched by Aeroporto di Bologna for the reduction, reuse, recovery and recycling of materials and without the overproduction of CO2 includes several actions, also in partnership with very important local and national entities.
Collection of used vegetable oils for the production of biodiesel (OVE Project)
The waste from the collection of used vegetable oils from the airport's Food & Beverage concessionaires is reused and transformed into biodiesel in Hera Group plants, thus shifting from a disposal cost to an incentive to encourage airport staff to embrace a greener, more sustainable and circular approach.
Separate collection of plastic from beverage vending machines for the total recycling and reuse at the airport (ReVending Project)
The collection and recycling of plastic is vital. The collaboration with the Hera Group, Corepla and the Argenta Group gave the green light to the project for the recovery and subsequent recycling of beverage vending machine cups and stirrers inside the airport.
Special containers are placed near the beverage dispensers (for the moment only in the areas used by those working at the airport, but in a second phase also in the dispensers for the public), which facilitate their collection to be picked up and taken to the Hera Group recycling centres without being contaminated by other materials, allowing them to be recycled and reused in large quantities.
Separate collection of plastic used for packaging in the cargo area
In the cargo terminal of the airport where Fast Freight Marconi (FFM) operates, a wholly-owned subsidiary of AdB, an initiative has been launched that focuses on reusing the packaging films that arrive with goods for subsequent transport by air or road.
The plastic from the films is compressed into briquettes of over 100 kg, which are then sold to Aliplast, a Hera Group company, to make a transparent packaging film comprising 80% recycled plastic.
The film produced is used by FFM, thereby reducing the amount of raw material used.
Transformation of organic waste into biomethane for buses and shuttles connecting the airport and the city
Together for a circular city': Aeroporto di Bologna, Hera and Tper have chosen this slogan to increase visibility on a project already underway which allows to turn the food waste produced at the airport into biomethane to be used for urban mobility on the buses of Tper's methane fleet. Thanks to a series of agreements and an entirely-local supply chain, the three Bolognese companies have developed a project that allows to completely eliminate the consumption of fossil fuels to power a significant share of the methane vehicles circulating in the urban area of Bologna.
About 450,000 cubic metres of biomethane will be supplied per year: this will allow biofuel vehicles to have the same emissions as an electric vehicle powered entirely by wind energy, adding up all the stages from extraction/production of the fuel to its use.
Separate waste collection
In February 2022, with the help of the Hera Group, Aeroporto di Bologna began an expansion of its separate waste collection, raising awareness and training the airport's various food and beverage concessionaires on this issue. To help increase the percentage of separated waste, retailers, car rental companies and other people working permanently at the airport were also involved, with very positive results.
BLQ as a sustainable destination - BOLOGNA AS A SUSTAINABLE DESTINATION
Thanks to the Municipal Administration's commitment to combating climate change, the City of Bologna has been selected as one of the 100 cities to participate in the so-called 'Mission Cities of smart cities with zero climate impact by 2030', as announced by the European Commission in April 2022. Aeroporto di Bologna intends to contribute to the achievement of this important goal by linking its own Net Zero Carbon initiatives with those of the City of Bologna.
At the same time, AdB intends to evaluate initiatives for air carriers in order to attract and reward those that produce less noise and/or lower CO2 emissions. Lastly, AdB promotes listening to and cooperating with local authorities, associations, sector operators and companies to share projects and initiatives aimed at achieving environmental, social and economic sustainability objectives, enhancing the local area itself and promoting sustainable tourism to/from Bologna.
Other initiatives in this regard concern the ESG-oriented improvement of our 'supply chain' by acting not only on the characteristics of the products and services purchased, but also on the qualification requirements of suppliers, with the aim of increasing the volume of 'green supplies' within total procurement.


Experience the luminous watercolours, great Canadian landscapes, and find expert art instruction from a leading watercolour painter. You are invited to hear her stories and come behind the scenes into an artist's studio!
As a visual artist, Marlene Madole is all about colour and light. It is the light, and her treatment of it, that draws you in. Whether it is a subject that you pass by everyday or a place that you have never been – see with the artist's eyes. Take home a memory!
I am arrested by the play of light falling on the most seemingly ordinary landscape. I love saturated colour, contrast, glancing sidelight with cast shadows curving over land, reflected light, blue sky days and translucent water. I am always curious to see what is down a new road and I return to places special to me.
You will be surrounded by her interpretation of the Canadian landscape: big September skies, shorelines of Georgian Bay, backwaters of the French River or Killarney Park, iconic larger-than-life fruit in her family's British Columbia orchard – all inspired by her travels across Canada, including local scenes of the Credit River and Caledon.
Visit Marlene at her Courtyard Studio / Gallery 7 at the Williams Mill in the historic hamlet of Glen Williams, between the Credit River and the Bruce Trail's Credit Valley Footpath. The Williams Mill is in the heart of the community, surrounded by places to linger over a lunch, a coffee, glass of wine or dinner.
Enter the courtyard at the Main Street level, look for the sidewalk leading to the yellow building, turn right and so that the yellow building will be at your back – straight ahead is the entrance to the courtyard. Follow the sidewalk around the corner, and you will see Studio / Gallery 7 tucked away on the left. Her cottage-like studio is annexed to the original hydro plant – a multi-level stone building within a mill complex repurposed for cultural uses.
Original art works: unframed printmaking, matted drawings, custom-framed watercolours (with archival matting) in a range of sizes, and acrylic paintings on panel or canvas. Gift Certificates are available for purchase.
An elected member and a Past President (2007-2009) of the Canadian Society of Painters in Water Colour (CSPWC). In 1995 Marlene established her Studio & Gallery at the Williams Mill in Glen Williams (a founding artist).
She is the recipient of Ontario Arts Council Grants and was awarded the City of Brampton Arts Acclaim Award.
A graduate of Sheridan College's School of Visual Arts, with further studies at the Ontario College of Art, Marlene is an experienced arts juror, with a growing curatorial practice.
An award-winning artist, Marlene has exhibited her work over 35 years in numerous group and solo exhibits, including five years in a row in the prestigious CSPWC's Annual International Juried Exhibition 'Open Water'.
Avignon, France: Au-delà des Mers: Between Friends Across the Seas – Entre Amis: Canada (CSPWC) and France Watercolor Society (SFA): Exchange Juried Exhibit.
Mexico City: International Watercolor Biennial, Museo Nacional de la Acuarela.
Art Gallery of Burlington: Presidents' Exhibition.
PAMA: Peel Art Gallery, Museum + Archives: CSPWC Diploma Collection.
Art Gallery of Mississauga: CSPWC 75th Anniversary – Brush with History.
Toronto: John B. Aird Gallery.
Vancouver: Federation Galleries – AIM For Arts International Juried Exhibition.
Arts & Letters Club of Toronto's 90th Anniversary Juried Art Exhibition.
Retrospective for the Image Matrix: Edition 15, Art Gallery of Mississauga.
As well as work on display in her own Studio / Gallery 7, she exhibits in regional shows including the Headwaters Arts Gallery in Alton, and the Helson Gallery in Halton Hills. Marlene's paintings of the French River and Georgian Bay are featured at The Lodge at Pine Cove on the French River.
Marlene has instructed watercolour painting from beginner to master classes, as well as drawing and printmaking. Painting demonstrations can be booked for your art group.
Private or Semi-Private Lessons are arranged to suit your schedule, including length, frequency, location, and pace customized for either an individual or small groups.
Choose from subjects such as: Watercolour Painting Techniques, Watercolour Rescue, Colour Mixing & Theory, Drawing, Plein Air Painting or Drawing, Still Life, Landscape, or Architectural Perspective.
Contact Marlene for information on scheduled 1-day workshops or series, or to inquire about individualized one-on-one lessons.
Glen Williams is north-west of Toronto (North of Hwy 401 and West of Hwy 410, approximately equal distance). Glen Williams is just west of Terra Cotta on the Credit River, 3.5 km west from the intersection of Old School Rd & Winston Churchill Blvd. Note the road name changes as you travel west: from Old School Rd to 22nd Side Road to Main Street (in Glen Williams).
From Toronto: Use Hwy 410 North, then it becomes Hwy 10: then follow the route below.
From Caledon or Brampton: From Hwy 10: Drive West for 11.5 km on Old School Rd (the first light after Hwy 410 becomes Hwy 10). A rural route for a nice day trip – note, some stop signs are only two-way, while others are all-way.
From Mississauga or Oakville: From Hwy 401: Exit 333 to Winston Churchill Blvd, Drive North for 15 km (15 minutes). Turn Left on 22 Side Rd (Old School Rd) for 3.5 km into the heart of Glen Williams.
From Guelph: From Hwy 7: Drive into Georgetown, Turn Left on Maple Ave, Turn Left on Mountainview Rd, Drive North into Glen Williams, Turn Right on Main St, Drive over the Credit River bridge.
Please call ahead to avoid disappointment: Marlene can be on site painting, sourcing images for future work, or on location giving a workshop or demo! When she is away, her studio may have reduced hours or be closed.


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Management decisions for good developer cost-benefit ratios
[This was originally posted at http://timstall.dotnetdevelopersjournal.com/management_decisions_for_good_developer_costbenefit_ratios.htm]
I've often seen development groups (or their managers) dismiss a good idea with "we can't afford it." The irony is that the group is already "affording" other expenses - developer salaries, MSDN licenses, hardware, and office space - so the question really becomes not "are there funds", but rather "what is the best way to spend our funds". There are at least three common examples where, for some reason, many managers shun the best cost-benefit ratio.
Problem 1: "We cannot afford a star developer - let's get two average developers instead."
The irony is that one star developer is far more profitable than two average developers. The star will build complex things that a dozen average developers will never be able to dream of. The star will write more solid code that spares you costly production errors. The star will solve the same problems faster by leveraging advanced techniques (like code generation, refactoring, or just elegant solutions). So, if you're creating a team of more than 10 developers, exchanging the bottom two spots for 1 star is a good investment. ThoughtWorks, a world-class consulting firm, does a good job of demonstrating the profitability of this business model.
Problem 2: "We cannot afford that tool - just do it another way instead."
Say you spend somewhere between $70K-$120K on an average developer (not just salary, but benefits, payroll taxes, etc...). Let's use $100K for easy numbers. At 50 work-weeks (assume 2 weeks of vacation), that's $2000 a week to pay for a developer - i.e. $50 an hour. So, a $50 tool that saves your developer one hour a year is a break-even investment.
Now about the "power tools" out there - like CodeSmith (for code generation), or ReSharper (for refactoring), or Simian (for detecting code duplication), or NDepend (for code metrics) - say it's a few hundred per tool (i.e. less than 0.5% of your developer labor cost). However, a tool like CodeSmith fundamentally changes the rules of the game, and can save a development team hundreds of hours. Sure, you can try to find open-source alternatives to each of these, and if you find something that fills the niche you need - great. A similar problem applies to hardware (where's there's not an open-source alternative)- for example when management "saves" $200 by not providing sufficient memory on a laptop, such that every hour of coding is sluggish due to a slow machine.
For many groups, a manager refusing to fund this kind of software engineering "equipment" (sounds classier than just "tools"), is like telling a construction worker to dig a trench - but we can't afford a $20 shovel, so use this spoon instead. Again, if a company is creating a 5 person development team, better to have only four people, but funded with the right equipment, then five developers who need to dig with spoons.
Problem 3: "We cannot afford that book - just see if you can figure it out from free, online tutorials."
Of course everyone knows that continuing education is vital in software engineering. In the manager's perfect world, they have a team of self-motivated developers who study on their own time, paying for their own materials, and learning at their own expense. And then, the manager (who has contributed nothing) gets to benefit from having all these learned developers. While yes, a developer is ultimately responsible for their own learning and career, a wise manager would realize that the company has a huge vested interest in the developer's learning, and would hence do things to encourage that learning.
Perhaps the most basic thing a manager could do is to have the company pay for a book that the developer is motivated to read. A book costs between $30 and $50 dollars. If a developer spends 20 of their own hours (on nights and weekends) over a month reading and absorbing that book, such that they can now profit the company with a new skill, this is a no-brainer. It could cost management thousands to send a developer to training (plus the days off work). It could cost management additional thousands to fix mistakes resulting from the developer not knowing that profitable technology. A book is cheaper, can be re-read by other developers, and is often read off the clock. Money speaks, so if management can't even encourage a motivated developer's learning with a $30 every other month, they're effectively telling developers that management doesn't value learning.
Labels: management
Management decisions for good developer cost-benef...
Bad estimate trick - playing people off of each other
BOOK: Patterns of Enterprise Application Architecture
Structs vs. Classes - seeing the functional differ...
Tips to incrementally check in code without breaki...
The non-financial resources at a manager's disposal
We need to get this done
Consider nixing the projector for quick demos
Chicago Code Camp website is live
How will you learn the next wave?


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MEMPHIS, Tenn. — A man accused of opening fire at an apartment complex is no longer facing charges.
Glen Miller was named the man responsible for the shooting that injured six people, but two days later, the charges were dropped.
Miller said it all started with a fight that almost caused him to lose his life.
Several people including children stood outside during a huge brawl at Hill View Apartments in South Memphis.
The next day it turned to much more. Miller was visiting his sister when he got out of the car.
"I just seen shots from a gun like boom boom boom boom. It happened so fast. I wasn't even out of the car 15 seconds," Miller said.
He was shot four times. His pregnant sister was also shot and was forced to have an emergency cesarean section giving birth to her now-healthy newborn.
But Miller said it wasn't looking good for him.
"I was reaching for the ambulance. I was reaching for them letting them know man I don't feel good I feel like I'm about to die," Miller said.
And he did twice, doctors had to resuscitate him and when he woke up he says he was surrounded by detectives and was put in handcuffs.
"I woke up and there was like three or four police officers outside of my door like they were guarding me and I was like, what's going on? And they were like, well you're being charged with six counts of aggravated assault and I'm like woah woah woah," Miller said.
Miller told police he didn't even have a gun when the shooting happened. He said he knows who did it but doesn't know why.
Miller's brother is working to file a lawsuit against the wrongful charge.
Miller hasn't eaten and can barely walk. It was even tough for him to talk during the interview.
Despite his journey at the hospital he's just glad he lives to see another day without any charges.
Miller does have a different case he's fighting in Marshall county. He actually missed his court date which was the day after he was shot.
Miller's family is working to get that straightened out with lawyers.
Police still have not arrested the person who was actually responsible for that shooting but Miller said several people identified him to police.


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Peter of Pisa (; ; 744 – 799 AD), also known as Petrus Grammaticus, was an Italian grammarian, deacon and poet in the Early Middle Ages. In 776, after Charlemagne's conquest of the Lombard Kingdom, Peter was summoned to the Carolingian court along with Paul the Deacon and Alcuin. Peter had originally taught at Pavia, in Italy.
Peter of Pisa was asked to be Charlemagne's primary Latin teacher.
Peter's poetry provides a personal look at the workings of the innermost sanctum surrounding Charlemagne.
Peter's grammar texts provide insight into the transformation Latin education underwent in this period.

As Christianity spread through Europe, so did Latin. Native speakers of Celtic or Germanic languages were rapidly becoming exposed to Latin: the language of the Church and international communication. In West Europe, from 400 until the late middle ages, the Bible and its commentaries were only available in Latin. Although some regions in West Europe were introduced to Latin centuries earlier by the Romans, these spoken languages evolved differently from the Latin of the written Bible.  To properly understand the Bible, and its commentaries, and the works of figures such as St. Augustine, knowledge of written Latin was a must. East of the Rhine, the people spoke an ancestor to today's German language because the Roman empire did not stretch that far. Learning Latin was challenging to peoples who were often not literate in their own native language. Another problem was posed by the inadequacy of the (outdated) teaching material that was available to instructors and missionaries. The materials were often designed for more advanced, native Latin speakers, or possibly Roman students. An example of this could be the Ars Maior by Donatus. Younger clergy in, for instance, Frankia or Germania, could see the study of Latin as a better way to understand the Bible, its commentaries, and prayers.

The Late Imperial teaching manuals are broken down into three categories:

•	Schulgrammatik was a systemic work that introduced pupils to basic concepts of the language such as parts of speech.

•	Commentary:  a type of work whose focus was originally written texts. Donatus' efforts widened this genre to the study of grammar.

•	Regulae works displayed variety in structure, with the main focus on form and proper Latin inflection.

A common theme of these works is that they were not written for education of inexperienced Latin learners. In the 600s, three new types of teaching manuals began to emerge that shaped the way Latin was taught during the time of the Carolingians:

•	Commentaries. These manuals were intended for advanced students with one of the goals being to see grammatical texts as literary commentaries.

•	Declinationes Nominum. Generally speaking, the goal in these texts was to construct the answer text by choosing from a vocabulary "bank".

•	Insular Elementary Grammars.

Christian culture was not introduced by the Carolingians; this movement was already evident in Visigothic Spain and Anglo-Saxon England at the time of conversion in the 7th century. Annexation of the Lombard kingdom (774) is also possibly linked with encouraging Charlemagne to embrace late Roman tradition. Classical studies began to be encouraged by him. Education was revived and Latinity began to rise. "The greatest contribution made by the Carolingian rulers to the revival of learning in their territories was thus less in legislating for it than in guaranteeing the Church's enjoyment of requisite material resources in the face of various conflicting interests and pressures."
"The Carolingian renaissance may be seen as an exercise in patronage on a grand scale by the Carolingian rulers." "Carolingian Military successes against groups like the Saxons and the Avars allowed the territory to gain wealth which was donated to the Church." Therefore, strengthening the presence of standardized written Latin language knowledge in Francia.

Around the year 800, Charlemagne (768-814) invited many great poets, grammarians, and other intellectuals to his court to feed his interest in the liberal arts. His influence and the ability to attract scholars to him created an influx. The Carolingian Renaissance spurred interest in classical study, and a revolution in teaching grammar and rhetoric. Classical and late-antique literature was being copied at an increased pace, and rare classical works were sought by Charlemagne. Paul the Deacon, Theodulf, Alcuin, Waldo of Reichenau, amongst others, joined Peter of Pisa at the emperor's side. Peter was formerly at the court of Desiderius. However, the famous names did not stay at Charlemagne's court for a long period of time, and their relatively brief cohesiveness was the result of shared scholarly culture.  Paulinus and Paul the Deacon were the first to leave no later than 790.

According to the emperor's biographer, Einhard, Peter of Pisa was Charlemagne's Latin grammar instructor. Peter's grammars largely incorporate the Insular Elementary style, while at the same time including distinct Carolingian aspects. One method which would become known by historians as distinctly the product of Peter is using series of questioning statements about the nature of a particular word. This type of method would remain in use for centuries for education purposes:

What is it?

What word class does it belong to?

Priscian is also known for including statements such as these in his manuals. However, the earliest datable specimen occurs in Peter of Pisa's grammar. Some words encourage very straightforward "discussion", while others are more flexible in the answers which are provided to the statements. Peter is also unique in his application of logic to elementary grammars.

By the end of the 8th century, Charlemagne's travel group has grown in number, and had become increasingly immobile. Poetry and poetic epistles provided entertainment on prolonged stoppages, as well as a way of competition between intellectuals. In addition, Latin poetry would become very popular in the 9th century. Almost all of those drawn to Charlemagne's court were poets in a way. In this environment, they were motivated by their new "elite" group and trying to overcome each other with wordplay and sly humor. The surviving record indicates that some rivalries were preserved as dramatized poetry. Peter was the emperor's amanuensis and wrote some mocking poems in his name. The following is an excerpt from a poem written by Peter, in the voice of Charlemagne, in ironical exaggeration of Paul's ability, and one of the first written manifestations of their rivalry:

He sent you, Paul, most learned of poets and bards,

to our back-water, as shining light with the various languages

you know, to quicken the sluggish to life by sowing fine seeds.

Paul replies in a way that downplays his ability and comically exalts Peter:

But lest it be said that I am an ignoramus in languages,

I shall repeat a few of the lines which were taught to me

as a boy; the rest have slipped my mind as old age weighs upon me.

One unique feature of Charlemagne court's writing, and Peter's, is "coterie poetry". Poems of this genre would make use of inside jokes, secret nicknames, and other aspects that indicate the readers be in a certain close-knit social group. Peter wrote to Paul the Deacon again:

You, hold off from gnawing the good brother with your teeth,

Who never is seen to be angry by the king's court.

An additional example of this kind of poetry could be found in the messages sent between Paul the Deacon, Peter of Pisa, and Charlemagne between 782 and 786. The three exchange riddles and sly remarks poking fun at one-another. Some epitaphs and acrostic poems would even draw in other court goers that were not part of the original dialogue, increasing the attractiveness of poetry for all court participants.

In addition, Peter wrote epistolary poems to Charlemagne, paying homage to him for building churches and acting as "father of his people".

Peter returned to Italy around 790, where he died no later than 799.

References

 Vauchez, Dobson, Lapidge, Walford (eds) Encyclopedia of the Middle Ages Routledge 2001.
 F. Brunhölzl, Histoire de la littérature latine au Moyen Âge, 1, 1, Turnhout, 1991, pp. 12–14.
 C. Jeudy, "Pierre de Pise", DLFMA, 1992, p. 1190.

See also
Carolingian Renaissance
Carolingian art

8th-century Latin writers
744 births
799 deaths
Grammarians of Latin
Medieval linguists
Linguists from Italy
8th-century Italian writers
8th-century Frankish writers
8th-century poets