The purpose of this presentation is to familiarize the trade with the new Importer Security Filing and Additional Carrier Requirements. Although this presentation attempts to mirror the Interim Final Rule, listeners are cautioned that the actual finalized regulatory text in the Interim Final Rule itself is binding.
While CBP will respond to some questions during this presentation, certain questions are more appropriate to be responded to in writing. Parties may submit questions about the general application of the new requirements to CBP via the Security_Filing_General@cbp.dhs.gov mailbox. CBP will review all questions received through this mailbox and will develop FAQs to be posted on the CBP website.
Questions relating to specific facts and circumstances of a prospective transaction can be the subject of a ruling request under Part 177 of the CBP regulations.
CBP is conducting an extended round of structured outreach activities to engage with the trade on all aspects of the rule.
In-person regional seminars and trade round table discussions at all of CBP's major seaports and other ports as needed.
Note: see the CBP.gov web site for latest information on the "10+2" Trade Outreach schedule.
Effective Date: The Interim Final Rule took effect on January 26, 2009(60 days after the publication date).
Compliance Date: 12 month delayed compliance period from the effective date to allow industry to comply with the new requirements. January 26, 2010.
The 12 month delayed compliance period may be extended if circumstances warrant.
The requirements in section 149.2(b) regarding the timing of transmission for 2 of the 10 Importer Security Filing elements and section 149.2(f) regarding the flexible requirements for 4 of the 10 elements are adopted as an interim final rule.
All other requirements in this rule are adopted as a final rule.CBP is not inviting comments on these requirements.
These elements are still required 24 hours prior to vessel lading.
Importers, in their initial filing, will be permitted to provide a range of acceptable responses based on facts available at the time, in lieu of a single specific response.
Importers will be required to update their filings as soon as more precise or more accurate information is available.
Container Stuffing Location and Consolidator (Stuffer) name/address.
ISF Importer must file this data as soon as possible, but no later than 24 hours prior to U.S. arrival.
During the first year, CBP will monitor all ISF submissions for timeliness, accuracy and completeness and will work with any non-complying ISF filer in order to help them adhere to the new requirements.
CBP will consider an entity's progress in the implementation of the rule during the delayed enforcement period as a mitigating factor in any enforcement action following the delayed enforcement period.
On the basis of information obtained during the structured review and public comments, DHS will undertake an analysis of the elements subject to flexibilities.
DHS, in coordination with other parts of the Executive Branch, will determine whether to eliminate, modify, or leave unchanged these requirements.
This only applies to the flexible requirements.
Interested persons are invited to submit written comments on those data elements for which CBP is providing some type of flexibilityand the requirements related to those elements discussed in section 149.2(b) and (f).
CBP also invites comments on the revised Regulatory Assessment and Final Regulatory Flexibility Analysis.
Federal eRulemaking Portal: http://www.regulations.gov. Follow the instructions for submitting comments via docket number USCBP-2007-0077.
Mail: Border Security Regulations Branch, Office of International Trade, U.S Customs and Border Protection, 799 9th Street, NW, Washington, DC 20001.
Comments are due by June 1, 2009.
CBP is committed to fully supporting the trade community in its efforts to successfully implement the requirements of this rule.
are making a good faith effort to comply with the rule to the extent of their current ability.
CBP will enforce the Importer Security Filing, vessel stow plan, and container status message requirements through the assessment of liquidated damages, in addition to penalties applicable under other provisions of law.
use the do not load (DNL) hold function for failure to comply with the "10+2" requirements (i.e. timely, accurate and complete filings).
This policy will last for twelve months after the effective date.
If circumstances warrant, CBP reserves the right to take any and all actions required to protect the security of the United States.
What is the Security Filing?
The Security Filing, commonly known as the "10+2" initiative, is a Customs and Border Protection (CBP) regulation that requires importers and vessel operating carriers to provide additional advance trade data to CBP pursuant to Section 203 of the SAFE Port Act of 2006 and section 343(a) of the Trade Act of 2002, as amended by the Maritime Transportation Security Act of 2002, for non-bulk cargo shipments arriving into the United States by vessel.
U.S. Bound Cargo (Includes FTZ and IT): requires the electronic filing of an Importer Security Filing (ISF) comprised of 10 data elements.
Transit Cargo (FROB, IE and TE): requires the electronic filing of an Importer Security Filing (ISF) comprised of 5 data elements.
Vessel Stow Plans required for arriving vessels with containers.
Container Status Messages required for containers arriving via vessel.
*ISFs for "exempt" break bulk shipments are required 24 Hrs prior to arrival.
All ISF filings are to be done electronically via vessel Automated Manifest System (AMS) or the Automated Broker Interface (ABI).
Note: CBP is not creating an internet-based web portal to accept the ISF filings. However, some service providers allow self-filers indirect access to CBP systems.
The party required to submit the Importer Security Filing (ISF) is the party causing the goods to enter the limits of a port in the United States. This party is known as the "ISF Importer".
Could be the owner, purchaser, consignee, or agent (e.g. customs broker).
For foreign cargo remaining on board (FROB), this party is the carrier (vessel operating carrier).
The party filing the immediate exportation (IE), transportation and exportation (T&E), or foreign trade zone (FTZ) documentation is the ISF Importer for those types of shipments.
The ISF Importer is ultimately responsible for the timely, accurate and complete submission of the ISF filing.
Pursuant to the Trade Act of 2002, where the presenting party is not able to reasonably verify the information required for the ISF filing, that party may submit the information on the basis of what it reasonably believes to be true.
The party who filed the Importer Security Filing must update the Importer Security Filing as additional or more accurate information becomes available.
The ISF Importer, as a business decision, may designate an authorized agent to file the Importer Security Filing on the ISF Importer's behalf.
If an agent is used for ISF purposes, a power of attorney (POA) is required.
Agents must have access to one of CBP's approved automated systems. For ISF requirements, the approved systems are the vessel Automated Manifest System (AMS) and the Automated Broker Interface (ABI).
The filing of an ISF does not constitute "customs business".
Exception is the "Unified Entry" filing.
The Vessel Operating Carrier (VOC) may hire a Non-Vessel Operating Common Carrier (NVOCC), or another party, to be its agent for ISF purposes.
POAs are executed between and maintained by private parties, not by CBP.
POAs must be done in English.
There is no particular form that needs to be followed. However, 19 CFR 141.32 contains an example of an acceptable general power of attorney.
POAs must be retained until revoked.
Revoked powers of attorney and letters of revocation must be retained for five years after the date of the revocation.
In most cases, existing POAs between certain parties (e.g. U.S. Customs Brokers and their clients) are broad enough to cover the new ISF requirements.
ISF filings must be secured by a bond. Continuous bonds will be accepted. Single Transaction Bonds (STBs) will be accepted on a case by case basis.
The ISF Importer must possess a bond or designate an agent to file under the agent's bond prior to filing of an ISF.
An agent can file under the agent's bond OR under the ISF Importer's bond.
Existing continuous bonds do not require a bond rider.
After the informed compliance period officially ends, the ISF Importer must provide a complete, accurate and timely filing or risk liquidated damages in the amount of $5,000.
ISFs are to be done at the "lowest" bill of lading level that has been (or will be) recorded in the vessel AMS system. CBP will accept an ISF at either the house bill of lading level or regular (i.e., simple, straight) bill of lading level.
While ISF filings may naturally match up with CBP Form 3461 Entries, there is no actual requirement that they do so.
Note: Container Numbers and Master Bill of Lading Numbers are OPTIONAL.
*In most cases, the ISF Importer and the Importer of Record Number will be the same.
**The ISF Importer must ensure that their importer ID number has been registered with CBP via the CBP Form 5106 process.
Identifier commonly known as the "11th Element".
Required as part of the ISF Filing. The ISF Importer, or their agent, must obtain this information and provide it to CBP as part of the ISF filing NLT 24 Hours prior to vessel lading for ISF-10 filings.
Absolutely necessary to properly link the Importer Security Filing (ISF) to the customs manifest data.
commodity HTSUS number when provided at the 10-digit level.
An importer may submit these elements once to be used for both Importer Security Filing and entry/entry summary purposes. If an importer chooses to have these elements used for entry/entry summary purposes, the Importer Security Filing and entry/entry summary must be self-filed by the importerorfiled by a licensed customs broker in a single transmission to CBP no later than 24 hours prior to lading.
In addition, the HTSUS number must be provided at the 10-digit level.
Manufacturer (Supplier) name/address, Country of Origin, Commodity HTS-6 must be linked at the shipment or entry level.
For each item of merchandise being imported, the ISF filer must tell CBP what the item is, who made or supplied the item and the item's country of origin.
Line-item linking is not required at the container, bill of lading or invoice level.
Postal Code information is "conditional". If a country uses postal codes, it will be required. The postal code is akin to the U.S. ZIP code.
During the structured review and flexible enforcementperiod, the lack of a postal code (when required) will result in an "accepted with warning" message.
Necessary because not all importations are exactly alike.
More types will be added if necessary.
CBP will work with the Trade to develop these types of filings.
This is where the goods are being shipped to the United States without a known U.S. Importer of Record 24 hours prior to lading. For example, a container full of cocoa beans. All ISF-10 elements are required.
Importer of Record #: A foreign entity may be identified as the Importer of Record Number. However, this must be updated prior to arrival if the actual element becomes known. This party's importer number (see CBP Form 5106) must be on file with CBP prior to the filing of the ISF.
Consignee #: Must be a U.S. entity. Could be the U.S.-based commodities agent, trading company, customs broker or some other party that has oversight over or nexus with the transaction. This must be updated prior to arrival if the element becomes known. (Often, this is the "Notify Party" on the customs manifest).
Buyer (Owner): May provide the name of the owner of the goods. This may be the same as the Seller (Owner) ISF-10 data element if the parties are the same.
Ship To Party: May provide the identity of the facility where the goods will be unladen (e.g., FIRMS code).
Type 03 "Household Goods and Personal Effects": This is where non-commercial goods are being shipped to the United States. For example, a student that has been studying overseas is shipping his/her goods home.
Importer of Record #: For U.S. Residents, a Social Security Number may be provided as long as it has been recorded by CBP (see CBP Form 5106).
In the alternative (and for non U.S. residents), a passport number, with country of issuance and a date of birth must be provided.
Consignee #: May be the same as Importer of Record #.
Seller (Owner): Owner's name and last foreign address.
Buyer (Owner): Owner's name and new address in the United States.
Ship To Party: Generally, the importer's new address in the United States.
Manufacturer (Supplier) name/address: Owner's last foreign address.
Country of Origin: Country code from Owner's last foreign address.
Container Stuffing Location: Follow normal requirements.
Consolidator (Stuffer) name/address: Follow normal requirements.
Bulk Cargo is exempt from all ISF requirements.
"Exempt" Break Bulk is cargo that has already received a temporary exemption from CBP for the purposes of the 24 Hour Manifest Rule requirements. An ISF for "Exempt" Break Bulk cargo needs to be filed no later than 24 Hours prior to U.S. arrival.
Cargo arrivals into the U.S. by modes other than vessel.
Department of Defense shipments that are exempt from manifest requirements.
The ISF Importer is ultimately responsible for updating the Importer Security Filing.
If an ISF agent was used to file the initial ISF, the agent can update the ISF via ABI or AMS.
If the ISF Importer needs to update the original ISF (e.g., the ISF agent refuses to update or withdraw the original filing), the ISF Importer must contact a CBP Client Representative and have the original filing cancelled before a "new" filing can be sent in to replace the original one.
The ISF must be updated, if after the filing and before the goods enter the limits of a port in the United States, there were changes to the information filed or more accurate information becomes available.
Note: The requirement to amend an ISF generally terminates when the vessel calls into the FIRST U.S. Port.
Note: If the ISF Importer took advantage of the flexibility as to interpretation for theManufacturer (or supplier), Ship to party, Country of origin, and Commodity HTSUS number, the ISF filing must be updated as soon as more precise or more accurate information is available, in no event later than 24 hours prior to arrival at a U.S. port.
CBP will return system messages to the ISF filer.
A unique identification number will be returned for all ISF filings that have been accepted; with the exception of the Unified ISF-5 filing.
A bill of lading "match" or "no match" message will be returned if an ISF matches to a bill. If "no match" the system will periodically check for a match. If a match is made, a message will be sent back to the filer.
If "no match" after 5 days, the system will return a warning.
If "no match" after 20 days, the system will return a second warning.
If "no match" after 30 days, the system will return a final warning message. Please note that the ISF will not actually "expire".
*After the informed compliance period ends, there will be conditional acceptance of an ISF-10 if the container stuffing location and consolidator name/address data elements are not provided with the initial ISF filing.
CBP will not send an actual DNL hold message to the ISF Filer. DNLs are made against bills of lading and are only sent to the appropriate carriers.
CBP will send a notification to the ISF Filer that their ISF prompted a DNL hold message.
This messaging will give the ISF Filer an opportunity to correct a mistake or mitigate a perceived national security risk prior to vessel lading.
For example, an ISF may have been sent with the HTS code of 2844.10 which indicates the presence of nuclear materials.
CBP will return system messages to the issuer of the bill of lading at the house or regular bill level (not the master bill level).
A status notification of "ISF on File" will be sent to the issuer of the bill of lading (e.g., NVOCC or carrier) and all second notify parties.
The issuer of the bill of lading (i.e., NVOCC or carrier) will not be able to access the actual ISF data elements.
This messaging was created at the request of the trade.
CBP will not issue "affirmative load" messages.
The vessel operator, vessel operating carrier and NVOCCs are not required to verify that an ISF has been filed against a bill of lading.The onus is on the ISF importer to provide a complete, valid and timely ISF to CBP.
In-bond shipments which, at the time of transmission of the Importer Security Filing as required by § 149.2 are intended to be entered as an immediate exportation (IE) or transportation and exportation (T&E) shipment, permission to divert the in-bond movement to a port other than the listed port of destination or export or to change the in-bond entry into a consumption entry must be obtained from the port director of the port of origin (of the original destination).
Such permission would only be granted upon receipt by Customs and Border Protection (CBP) of a complete Importer Security Filing as required by part 149.
Q.	Liquidated Damages in the first year?
Q.	Do Not Load (DNL) hold messages for ISF compliance reasons in first year?
Q. DNLs for national security reasons?
Carriers (i.e. the Vessel Operator) are required to submit a vessel stow plan for vessels destined to the United States.
Required no later than 48 Hours after departure from the last foreign port. For voyages less than 48 Hours, the stow plan is required prior to arrival.
Vessel Automated Manifest System (AMS), secure file transfer protocol (sFTP) or e-mail.
Carriers are required to submit container status messages (CSMs) to CBP daily for certain events relating to all containers destined to arrive within the limits of a port in the United States by vessel.
CSMs are required for empty containers.
CSMs created under either the American National Standards Institute (ANSI) X.12 standard or the United Nations rules for Electronic Data Interchange For Administration, Commerce and Transport (UN EDIFACT) standard are acceptable.
Carriers must submit a CSM when any of the required events occurs if the carrier creates or collects a CSM in its equipment tracking system reporting that event.
Carriers are not required to create or collect any CSM data other than those which the carrier already creates or collects on its own and maintains in its electronic equipment tracking system.
Carriers must submit CSMs no later than 24 hours after the message is entered into the carrier's equipment tracking system.
Carriers may transmit their "global" CSM messages, including CSMs relating to containers that do not contain cargo destined for importation into the United States and CSMs relating to events other than the required events.
By transmitting CSMs in addition to those required by this interim final rule, a carrier authorizes CBP to access and use that data.
(6) Vessel identification associated with the message if the container is associated with a specific vessel.
Carriers are exempt from the CSM requirement for bulk and break bulk cargo.
Carriers must submit CSMs via the CBP-approved electronic data interchange system. The current electronic data interchange system for CSMs approved by CBP is sFTP.
Internal Revenue Service (IRS) number, Employer Identification Number (EIN), Social Security Number (SSN), or CBP assigned number of the entity liable for payment of all duties and responsible for meeting all statutory and regulatory requirements incurred as a result of importation.
The importer of record number for Importer Security Filing purposes is the same as "importer number" on CBP Form 3461.
The importer of record number can be a foreign entity. However, a U.S. entity must be provided for the consignee number element.
For goods intended to be delivered to an FTZ, the IRS number, EIN, SSN, or CBP assigned number of the party filing the FTZ documentation with CBP must be provided.
Internal Revenue Service (IRS) number, Employer Identification Number (EIN), Social Security Number (SSN), or CBP assigned number of the individual(s) or firm(s) in the United States on whose account the merchandise is shipped. This element is the same as the "consignee number" on CBP Form 3461.
Name and address of the last known entity by whom the goods are sold or agreed to be sold. If the goods are to be imported otherwise than in pursuance of a purchase, the name and address of the owner of the goods must be provided.
The party required for this element is consistent with the information required on the invoice of imported merchandise. See 19 CFR 141.86(a)(2).
A widely recognized commercially accepted identification number for this party may be provided in lieu of the name and address. CBP will accept a DUNS number in lieu of the name and address.
Name and address of the last known entity to whom the goods are sold or agreed to be sold. If the goods are to be imported otherwise than in pursuance of a purchase, the name and address of the owner of the goods must be provided.
Name and address of the first deliver-to party scheduled to physically receive the goods after the goods have been released from customs custody.
If unknown, provide the name of the facility where the goods will be unladen.
May provide a FIRMS code of a warehouse or terminal if the specific ship to name/address is unknown at the time of the filing. For example, a container freight station is acceptable.
May provide the name and address of an in-land distribution center if the specific ship to name/address is unknown at the time of the ISF filing.
2. Or, name and address of the supplier of the finished goods in the country from which the goods are leaving.
In the alternative, the name and address of the manufacturer (or supplier) that is currently required by the import laws, rules and regulations of the United States (i.e., entry procedures) may be provided (this is the information that is used to create the existing manufacturer identification (MID) number for entry purposes).
Country of manufacture, production, or growth of the article, based upon the import laws, rules and regulations of the United States. This element is the same as the "country of origin" on CBP Form 3461.
Duty/statistical reporting number under which the article is classified in the Harmonized Tariff Schedule of the United States (HTSUS). The HTSUS number must be provided to the six-digit level.
In the alternative, the filer may choose to provide the HTSUS number to the 10-digit level.
Name and address(es) of the physical location(s) where the goods were stuffed into the container. For break bulk shipments, the name and address(es) of the physical location(s) where the goods were made "ship ready" must be provided.
The "scheduled" stuffing location may be provided.
Name and address of the party who stuffed the container or arranged for the stuffing of the container. For break bulk shipments, the name and address of the party who made the goods "ship ready" or the party who arranged for the goods to be made "ship ready" must be provided.
If no consolidator is used, e.g., "factory load" shipments, provide the name/address of the manufacturer (supplier).
Name and address of the party who initiates the reservation of the cargo space for the shipment.
The HTSUS number may be provided to the 10-digit level.
Port code for the foreign port of unlading at the intended final destination.
CBP will accept the Bureau of Census "Schedule K" codes.
City code for the place of delivery.
Foreign location where the carrier's responsibility for the transport of the goods terminates.
UN LOC codes and Bureau of Census "Schedule K" codes are acceptable.
Foreign Port before vessel departs for U.S.
Section 203 (b): Secretary shall "…require…additional data elements for improved high-risk targeting, including appropriate security elements of entry data…to be provided as advanced information …prior to lading…" at the foreign port.
Requires consultation with stakeholders (including COAC) and that the Secretary "identify to them the need for such information and the appropriate timing of its submission".
Requires consideration of costs, benefits, and feasibility of requiring additional non-manifest data, reducing the time period for revising cargo manifests and for submission of certain elements of entry data.
Filing/subjectivity -. . . . . . . . . . . . . . . . processing. . . injury combined condition. . . . . . . ppd. . . . . . .


text:
Brigham CEO stands out for outside jobs
By Liz Kowalczyk Globe Staff,June 1, 2016, 9:15 p.m.
Dr. Elizabeth Nabel, chief executive of Brigham & Women's Hospital.Wendy Maeda/Globe staff/file/Globe Staff
Dr. Elizabeth Nabel is paid well — $1.3 million in salary alone in 2013 — to run Brigham and Women's Hospital, one of the nation's premier medical centers. She also finds time to hold three other paying positions, which is unusual for a Boston hospital president.
The National Football League last year hired Nabel — a prominent national leader in cardiac medicine and research who holds six honorary doctorates — to serve as its lead medical consultant for an undisclosed amount of money.
She also earns $175,000 annually plus stock to sit on the board of the Dublin-based technology company Medtronic, and a confidential fee as a director for a Cambridge biotechnology company.
While other chief executives of large nonprofit hospitals engage in extracurricular work, Nabel stands out for the number of outside jobs on her plate as she tries to build the hospital's national reputation. Brigham trustees approved the positions — and said they closely monitor her hours — because they also help Nabel build her business acumen, said Scott Sperling, board chairman and co-president of Boston investment firm Thomas H. Lee Partners.
But certain hospitals limit the practice. The outside positions, while they can be personally lucrative and bolster an institution's standing, carry with them potential risks.
A congressional committee report last week pointed to Nabel as part of an NFL effort to "steer funding" for a landmark concussion study from the National Institutes of Health away from a group of respected brain researchers. The scientists had previously helped establish a link between football and long-term brain damage. In a statement to the Globe, Brigham spokeswoman Erin McDonough said Nabel "was working through the appropriate channels to ensure this important research be conducted in a way that would yield the best possible science."
Nabel, 64, has been president of the Brigham since 2010, and is a former director of the National Heart, Lung, and Blood Institute. She graduated from Cornell University Medical College and trained at the Brigham. Dr. Thomas Lee, a former Partners executive and chief medical officer at Press Ganey, a hospital consulting company, developed a friendship with Nabel during medical school and residency.
He said he can't imagine her giving any job less than full attention.
Lee said Nabel "doesn't like to make mistakes" and is unfailingly thorough about her work. During training, her notes about patients were so all-encompassing that other residents kidded her about them.
"I once made a joke about how she had omitted the family history of the dog," Lee wrote in an e-mail. "All I can say is that her entire life, she has been known as someone really compulsive about doing a good job."
According to a Globe survey, Boston hospitals have adopted a range of practices and policies on outside work. Beth Israel Deaconess Medical Center, which like the Brigham is a Harvard teaching hospital located in Boston, prohibits its chief executive from holding outside paid positions — though it declined to discuss its reasons.
Boston Medical Center limits its chief executive to one paid board membership because of her other time commitments; Kate Walsh this year joined the board of Lexington technology company Imprivata and receives $75,000 in stock annually.
Boston Children's Hospital chief executive Sandra Fenwick volunteers on several boards — as do many hospital heads — but has no paying positions. Massachusetts General Hospital president Dr. Peter Slavin recently joined the board of American Well, a Boston telehealth company; neither the company nor the hospital would disclose his compensation.
Dr. Laurie Glimcher, the incoming head of the Dana-Farber Cancer Institute, sits on the corporate boards of pharmaceutical giant Bristol-Myers Squibb and lab equipment maker Waters Corp., and the hospital is allowing her to keep those positions — with monitoring for conflicts of interest.
At the Mayo Clinic in Minnesota, president Dr. John Noseworthy does not perform any outside board work, while Dr. Paul Rothman, chief executive of Johns Hopkins Medicine, earned $100,000 plus stock options as a Merck & Co. director in 2015.
Sperling said Nabel's outside positions ultimately benefit the hospital — especially her involvement with the NFL, which he called "one of the highest-profile organizations in the world." She is developing relationships with the 30 team owners, who are prominent in their communities. "That has been very helpful in terms of the overall Brigham profile," he said.
Asked about the congressional report, Sperling said "there is nothing in it that gives the board concern that Betsy has done anything inappropriate."
In terms of the board directorships, Sperling said Nabel is gaining experience in how large and small companies are managed. "It has great value to us in terms of broadening her skills as a CEO," he said. While purchasing decisions don't usually reach her, he said she would remove herself from any business discussions involving products sold by Medtronic or Moderna Therapeutics, the biotech company for whom she is a director.
Partners HealthCare, the Brigham's parent company, limits executives' outside activities to 52 days a year; Nabel spent 21.5 days on these positions in 2015, McDonough said. Nabel said in an interview with the Globe a year ago that she was working one day a month for the NFL plus some nights and weekends. Medtronic has four regular board meetings a year in Ireland, plus committee meetings. Moderna declined to provide information.
Henry Stoever of the National Association of Corporate Directors, a nonprofit organization in Washington, said time spent outside the office is not the only possible pitfall. "You might be spending a lot of mind time thinking about helping that board and how can I help that company. It is an area to always be concerned about" — and a reason why organizations set limits, he said.
When the NFL tapped Nabel last year as its first chief health and medical adviser, some wondered at the choice of a cardiologist, given the focus on the prevalence of player concussions and whether the NFL has downplayed the dangers.
Neurosurgeon Dr. Robert Cantu, a concussion expert at the Boston University School of Medicine, said her role entails more than offering advice about brain injuries. David Hovda, a member of the UCLA Brain Research Institute, said he was surprised the league did not pick an expert on traumatic brain damage but said Nabel's former leadership role at the National Institutes of Health might be viewed as more valuable. Her stature and prominent position adds legitimacy to the NFL's assertions that it is trying to address the problem, he said.
The Massachusetts attorney general's office warned five years ago about possible pitfalls in nonprofit leaders taking outside paid positions. In a review of compensation for former Blue Cross Blue Shield of Massachusetts chief Cleve Killingsworth, the office noted that he served on 14 outside boards, three of which paid him "significant compensation" and elected him after he became chief executive. A report said the practice raised broader concerns about whether chief executives were using their positions, considered a charitable asset, to leverage paying positions.
Sperling said the Brigham and Nabel have been "incredibly careful" not to allow the NFL to misuse her position. The NFL's use of her name and the Brigham's name is reviewed quarterly by Partners and the Brigham.
"When Dr. Nabel interacts with media or other entities on NFL business, she and the NFL are careful to ensure that it's clear that she is participating as a strategic advisor to the NFL, not as president of BWH," McDonough wrote in an e-mail.
Liz Kowalczyk can be reached at kowalczyk@globe.com.

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: Windows memory allocation questions I am currently looking into malloc() implementation under Windows. But in my research I have stumbled upon things that puzzled me:
First, I know that at the API level, windows uses mostly the HeapAlloc() and VirtualAlloc() calls to allocate memory. I gather from here that the Microsoft implementation of malloc() (that which is included in the CRT - the C runtime) basically calls HeapAlloc() for blocks > 480 bytes and otherwise manage a special area allocated with VirtualAlloc() for small allocations, in order to prevent fragmentation.
Well that is all good and well. But then there are other implementation of malloc(), for instance nedmalloc, which claim to be up to 125% faster than Microsoft's malloc.
All this makes me wonder a few things:

*

*Why can't we just call HeapAlloc() for small blocks? Does is perform poorly in regard to fragmentation (for example by doing "first-fit" instead of "best-fit")?

*

*Actually, is there any way to know what is going under the hood of the various API allocation calls? That would be quite helpful.

*What makes nedmalloc so much faster than Microsoft's malloc?

*From the above, I got the impression that HeapAlloc()/VirtualAlloc() are so slow that it is much faster for malloc() to call them only once in a while and then to manage the allocated memory itself. Is that assumption true? Or is the malloc() "wrapper" just needed because of fragmentation? One would think that system calls like this would be quick - or at least that some thoughts would have been put into them to make them efficient.

*

*If it is true, why is it so?

*On average, how many (an order of magnitude) memory reads/write are performed by a typical malloc call (probably a function of the number of already allocated segments)? I would intuitively says it's in the tens for an average program, am I right?

A: *

*Calling HeapAlloc doesn't sound cross-platform.  MS is free to change their implementation when they wish; advise to stay away. :)

*It is probably using memory pools more effectively, much like the Loki library does with its "small object allocator"

*Heap allocations, which are general purpose by nature, are always slow via any implementation.  The more "specialized" the allocator, the faster it will be.  This returns us to point #2, which deals with memory pools (and the allocation sizes used that are specific to your application).

*Don't know.

A:
From the above, I got the impression that HeapAlloc()/VirtualAlloc() are so slow that it is much faster for malloc() to call them only once in a while and then to manage the allocated memory itself. Is that assumption true?

The OS-level system calls are designed and optimized for managing the entire memory space of processes. Using them to allocate 4 bytes for an integer is indeed suboptimal - you get overall better performance and memory usage by managing tiny allocations in library code, and letting the OS optimize for larger allocations. At least as far as I understand it.

redpajama_set_name: RedPajamaStackExchange


text:
A day in the life of a SYSTRA apprentice - Jason Munslow
It's not often that you receive a short-notice summons to the palace of Westminster, but it happened to me just a few weeks ago.
It was not, however, a desperate plea from Theresa to come and sort out our relationship with Europe – I was told that I'd been nominated as the National College for High Speed Rail (NCHSR) Apprentice of the year, and that I, along with my line manager Andy Gubbins, were to attend a parliamentary reception.
I've been attending the college since it first opened in October 2017, it offers a unique set of rail-focused courses. Being first introduced to me by a relative at HS2, the employer support offered by the college was a major factor in persuading me to take up an apprenticeship rather than university degree. The Level 5 Operations and Management apprenticeship was my choice and it has already given me the opportunity to develop my skills in presentation, organisation and professionalism.
With plenty to organise, event day came around very quickly and I soon found myself onboard the 11:50 train direct to Euston. Distracted only by a quick visit to the shop, the journey time was well spent discussing professional development with Andy and soon enough we were stepping out onto the streets of the capital.
Upon arrival, I learnt just how ruthless our famous capital can be…
As we approached the tube, we were approached by a confused traveller on the underground platform. Despite likely knowing less about the city than they did, we stopped to offer our help. Having opted to stand and help, Andy speedily answered the question and boarded the tube. In just a matter of seconds, the doors began to close. It was too late; I could only watch as the train moved away, taking my bewildered manager with it.
Effective communication and clever planning ensured that we could rendezvous at our final stop, however, upon emerging from the tube station we were met by crowds of tourists who had travelled to view the awards reception. It's possible that they were also there for some princess' wedding day, but I doubt it.
Entering Westminster was an interesting experience. A full airport immigration process is bolstered by a balcony manned by three machine gun-wielding police officers – the type who like to stare but not smile. Other than being questioned over a bottle opener on my keys, we passed through smoothly and were led into one of the most impressive buildings I've ever seen. Walking through the halls, it was clear to see that no expense had been spared and thinking of the decisions been made around us was enough to send a chill up your spine.
After weaving our way through several grand corridors, we were told to wait until the room had been prepared, and as far as waiting rooms go, this was different to say the least….
In limbo between the House of Commons and the House of Lords, we waited to be called through. Right on time the crowds were ushered into the room, visitors from Parliament, HS2 and other reputable companies were on hand to give their views on the college and future aspirations.
The awards ceremony began with the right honourable Dame Rosie Winterton MP given the duties of presenting. As she announced the results in reverse order I was announced as runner up, whilst not the winner, both my line manager and I were extremely proud of my achievement.
It was a hugely enjoyable experience with excellent guest speakers, networking opportunities and not forgetting a good supply of free drinks and canapes. An experience I have already shared many times, and unlikely to ever forget. I would not have been able to experience this without the apprenticeship opportunity SYSTRA gave me and the work and dedication of the National College for High Speed Rail and its employees.
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news201118-pic2.jpg


Rebrnd is a talented artist, DJ and producer. Making dance parties hip for a few years now out in California. Check out this interview to learn more about him.
Hello! I am an artist, DJ and music producer from California. I go by the name REBRND. I choose the name REBRND because to me the name is a reminder that I don't have to settle for who I was yesterday I can constantly rebrand (get it) myself into something better and better each day. Not solely with music but also better myself as a person in general. Music is a HUGE part of my life though and the knowledge behind it is endless; so I consider myself a life-long student of sound. I am always looking for ways to better understand music and its relation to the human experience and at the same time focus a lot of energy on improving my musical creativity. Currently working on various music projects including an EP.
What do you love about remixing popular songs, such as the MGMT song you posted of yourself on Instagram?
The song in that video I posted on Instagram was actually a remix done by a DJ duo called Two Friends. I was sitting at the studio one day and decided to play around with one of my drum pads. Their version of MGMT's "Kids" is one of my favorite remixes so, while at the studio, I decided to take a break from working on music to create my own edit of that song on the drum pad. It was a lot of fun! I recently did another video with a San Holo track. I plan on doing more of those videos.
I am planning to release more of my own remixes but so far I have only released one. I remixed Zedd's "The Middle" back in April. I choose to remix that song because I love Maren Morris' voice on it and felt the urge to make something using her vocals. Had a great time working on that one.
I have been producing music for the past 4 years but I just recently started releasing music this past year. It takes a long time to get anywhere near producing a decent track for me right now so I am patiently working on perfecting my craft.. still learning (again back to the REBRND name). Still trying to improve each day.
Music is very special to me. My dad taught me a few instruments when I was a kid and the older I got the more I appreciated it. I started DJing then eventually got into music production and immediately fell in love with it. Music is the one thing everyone in the world shares in common. We may not all like the same music but we all LOVE music. Essentially its the one thing that has the power to unite us all.
With the innovation of VR/AR technologies do you see yourself incorporating that kind of elements into your shows?
I have yet to design a stage for my performances but I think it would be really cool to use those technologies at shows. I have heard people talk about using VR/AR but I haven't yet seen anyone implement them. Would be cool to have people visit your show at home through VR or AR but then again I love the human to human interaction at shows - can't beat that!
What inspired "Who We Are"?
I made the instrumental and collaborated on this track with an artist that goes by the name "The Free". I have been a fan of The Free's music for a long time so when he agreed to work with me on this track I was super excited. The Free is such a talented artist and all of his music is very positive and uplifting it was an honor to have been able to work with him. "Who We Are" carries a positive message and it is something I want to do more of. Make positive music.
How long does it typically take for you create a song from start to finish?
It depends. Some songs can take years to finish while others can take me a month.
What kind of programs do you use to create your music?
I use Ableton Live to produce the tracks and Pro Tools to record do the mixing and mastering.
What advice do you have for the music producer/DJ just starting out? How do you build a following these days? Is it just performing in clubs/venues or is it just putting the music out there?
Building a following is not really one of my goals I simply want to produce great music that people can enjoy listening to. My advice would be to always work on improving the art. Really learn from others with more experience, take classes, look up tutorials online, understand music theory, understand how sound works etc. I would also recommend reading the book This Is Your Brain on Music by Daniel Levitin. This book helped me better understand how important music is.
4 Generators AND My desktop computer to work on music (hopefully there is wifi).
If you could put on the most epic dance party where would it be where you would get to perform?
It would be in one of the islands by the beach! Love the ocean and island vibes. I would get Kygo, Matoma, and San Holo to perform.
To the 90s so I can watch 90s Television.
I listen to a lot of different style of music. Some artist I am currently listening to are San Holo, Jeremey Zucker, Kygo (of course!), Matoma.. I also enjoy classic 80s music and a bunch more stuff the list is long. Always looking up new artist too.


text:
How Toyota Will Be First With a Fuel-Cell Car
Toyota says it has reduced the cost of fuel cells significantly enough to sell hydrogen cars for under $100,000.
by Kevin Bullis
Toyota says it's made several advances to hydrogen fuel cells that will make them significantly cheaper, and will allow the company to sell a car using the low-pollution technology in 2015—years before its competitors.
Hydrogen concept: Toyota plans to display this new hydrogen fuel-cell concept car at the Tokyo Motor Show.
The car will be expensive: between $50,000 and $100,000. But that's a big improvement over the million-dollar cost of experimental fuel-cell vehicles in years past.
Toyota will display a concept version of the car—featuring a fuel cell instead of an engine—this month at the Tokyo Motor Show. While the concept car might not outwardly resemble the final car, the fuel-cell system inside will be worth looking at because it will likely be similar to the one in the production version. Toyota says the fuel-cell system is smaller and uses much less of an expensive ingredient—platinum—than earlier versions.
Like a battery, a fuel cell produces electricity. But unlike a battery, it is fed by a tank of hydrogen. Inside the fuel cell, platinum serves as a catalyst that facilitates reactions between the hydrogen and oxygen, producing electricity that powers the car and water vapor that comes out of the tailpipe. And while batteries in electric vehicles can take hours to recharge, a hydrogen tank can be refilled in about the time it takes to fill a conventional gas tank.
However, that advantage is limited for now because there aren't many places to refuel a hydrogen vehicle. Other automakers, including General Motors, plan to sell fuel-cell vehicles starting around 2020, when costs will likely have come down still more, and when there could be more places to refuel. Several governments are funding hydrogen fueling stations.
Although there are still challenges to making fuel cells for mass-market vehicles, automakers say they could eventually go a long way toward meeting ever-stricter fuel economy and greenhouse gas regulations around the world, as well as requirements that a growing fraction of the cars they sell in places such as California emit no pollution from their tailpipes. Fuel-cell vehicles might be more attractive than battery-powered vehicles because, in addition to faster refueling times, they typically have a longer driving range (see "Why Toyota and GM Are Pushing Fuel-Cell Cars to Market" and "Ford, Daimler, and Nissan Commit to Fuel Cells").
Fuel-cell vehicles could also let consumers take advantage of cheap natural gas in places such as the United States, since natural gas is the least expensive source of hydrogen. While producing hydrogen from natural gas releases carbon dioxide, the emissions would still be about half as much as those from gasoline-powered cars today.
Toyota has significantly decreased the amount of platinum needed in fuel cells and could ultimately get the amount down to a level that's comparable to what cars already have in their catalytic converters, says Justin Ward, general manager of powertrain system control at the Toyota Technical Center in Gardena, California. Fuel-cell vehicles won't need catalytic converters because they don't emit pollutants.
Toyota reduced the amount of platinum by modifying the catalyst to make it more effective (the company isn't saying exactly how) and by developing precise equipment for applying the catalyst to ensure that none is wasted. "Years ago we were literally taking spatulas and applying the platinum," Ward says.
Another reason the system is cheaper is that it requires fewer fuel cells to be stacked together than previous concept cars did. Toyota accomplished this in part by improving the design of the cell. The electricity-generating reactions inside the cell take place at two electrodes separated by a membrane that allows hydrogen ions to pass from one side of the cell to the other. Toyota engineers modified the membrane to allow protons to pass more freely, which increases the amount of power that each fuel cell can generate.
Toyota is extending the cars' range between fill-ups by borrowing technology from its hybrid vehicles. Fuel cells, like conventional engines, are at their most efficient when they run at a steady rate, rather than quickly increasing or decreasing power output during acceleration and braking. So Toyota is adding a battery to the hydrogen car to provide boosts of power for acceleration, reducing the strain on the fuel cell.
Kevin Bullis


text:
<?php
namespace AspectMock;

/**
 * `AspectMock\Test` class is a builder of test doubles.
 * Any object can be enhanced and turned to test double with the call to `double` method.
 * This allows to redefine any method of object with your own, and adds mock verification methods.
 *
 * **Recommended Usage**:
 *
 * ``` php
 * <?php
 * use AspectMock\Test as test;
 * ?>
 * ```
 *
 * If a class name is passed to `test::double`, instance of `ClassProxy` class is returned.
 * You can redefine class methods the same way, also mock verification methods are included as well.
 *
 */
class Test {

    /**
     * test::double registers class or object for to track its calls.
     * In second argument you may pass return values of its methods to redefine them.
     * Returns an object with call verification methods.
     *
     * Example:
     *
     * ``` php
     * <?php
     *
     * # simple
     * $user = test::double(new User, ['getName' => 'davert']);
     * $user->getName() // => davert
     * $user->verifyInvoked('getName'); // => success
     *
     * # with closure
     * $user = test::double(new User, ['getName' => function() { return $this->login; }]);
     * $user->login = 'davert';
     * $user->getName(); // => davert
     *
     * # on class
     * $ar = test::double('ActiveRecord', ['save' => null]);
     * $user = new User;
     * $user->name = 'davert';
     * $user->save(); // passes to ActiveRecord->save() and does not insert any SQL.
     * $ar->verifyInvoked('save'); // true
     *
     * # on static method call
     *
     * User::tableName(); // 'users'
     * $user = test::double('User', ['tableName' => 'fake_users']);
     * User::tableName(); // 'fake_users'
     * $user->verifyInvoked('tableName'); // success
     *
     * ?>
     * ```
     *
     * @param $classOrObject
     * @param array $params
     * @return Core\ClassProxy|object
     */
    public static function double($classOrObject, $params = array())
    {
        if (is_object($classOrObject)) {
            Core\Registry::registerObject($classOrObject, $params);
            return new Core\InstanceVerifier($classOrObject);
        } elseif (is_string($classOrObject)) {
            Core\Registry::registerClass($classOrObject, $params);
            return new Core\ClassVerifier($classOrObject);
        }
    }

    /**
     * Dummy is a class instance created without calling a constructor.
     * In a second argument you can redefine methods of that class instance.
     *
     * ``` php
     * <?php
     * $connection = test::dummy('MySQLConnection', ['connect' => null]);
     * ?>
     * ```
     *
     * @param $className
     * @param array $params
     * @return Core\ClassProxy|object
     */
    public static function dummy($className, $params = array())
    {
        $reflectionClass = new \ReflectionClass($className);
        $instance = $reflectionClass->newInstanceWithoutConstructor();
        return self::double($instance, $params);
    }

    /**
     * Fake has all methods replaced with dummies and created without calling a constructor.
     *
     * ``` php
     * <?php
     * test::fake('MySQLConnection');
     * ?>
     * ```
     *
     * @param $className
     * @return Core\ClassProxy|object
     */
    public static function fake($className)
    {
        return self::fakeExcept($className, []);
    }

    /**
     * As you may guess fakeExcepts is a fake where some methods are not replaced with dummies.
     *
     * ``` php
     * <?php
     * test::fakeExcept('MySQLConnection',['getConnectionName']);
     * ?>
     * ```
     *
     * @param $className
     * @param array $exceptParams
     * @return Core\ClassProxy|object
     */
    public static function fakeExcept($className, array $exceptParams)
    {
        $reflectionClass = new \ReflectionClass($className);
        $methods = $reflectionClass->getMethods(\ReflectionMethod::IS_PUBLIC);
        $instance = $reflectionClass->newInstanceWithoutConstructor();
        $params = array();
        foreach ($methods as $m) {
            if (in_array($m->name, $exceptParams)) continue;
            $params[$m->name] = null;
        }
        return self::double($instance, $params);
    }

    /**
     * Clears test doubles registry.
     * Should be called between tests.
     */
    public static function clean()
    {
        Core\Registry::clean();
    }

}

redpajama_set_name: RedPajamaGithub


The Budget Advisory Committee has a membership of twenty-two participants, including seven community members, two Principals, two representatives from the Parent Leadership Academy, two representatives from DELAC, two representatives from each bargaining unit (TRUE, CSEA and TRPOA), the Deputy Superintendent/Administrative Services, Executive Director/Fiscal Services, and Director/Categorical Budgets.
Our Budget Advisory Committee members are dedicated advocates for the students of the Twin Rivers USD and are committed in assisting the District make the most of the education funding in these difficult budget times.
We greatly appreciate the support and valued budget ideas we receive from our Budget Advisory Committee!
at 6:00 p.m., in the Sycamore Room.


I'm a self taught artist who loves being in the great outdoors. I walk every day and this is where the inspiration for most of my work comes from. Through my love of the countryside and walking, I see the landscape in blocks of colour and this is reflected in my paintings. My work is exhibited in galleries throughout the UK. Some of my recent work has been for ITV's Emmerdale village, and to paint a full wall mural for Elterwater hostel in the Lake District. I've also been lucky enough to paint a lifesize Herdwick Ewe and Lamb for the Go Herdwick art trail for the Calvert Trust in the Lake District. I live in North Yorkshire with my husband, 2 children and border collie, who insists on bringing a ball to play with when I should be painting. My favourite place is the Lake District, Cumbria, so many of my paintings are from the summits of fells I've walked with my family.
I mainly work on boxed canvas in all sizes and use a high quality emulsion along with acrylic paints to create my work. All of my paintings are signed, painted around the sides and varnished for protection, they are ready to hang on the wall. I'm adding to my collection all the time and happily accept commissions.
All work is my own and all paintings, even if they are of the same place, are original. If you have a specific place you would like painting, please get in touch and I would be happy to help.
Sam Martin has 100 artworks.
Sam Martin does not have any gifts on show at the moment.
Thanks for help with sorting out vouchers to enable purchase of artwork which looks fantastic in my lounge. Great colours and nice size piece.
Great picture from a talented artist, Colours perfectly reproduced on website. Just what I wanted.
Delivered quickly and very securely wrapped.
Very user-friendly website. Easy to navigate and quickly find what you want. I've been buying from ArtGallery for a few years and have always been delighted with their high quality art. I've recommended them to several people. Just one problem - I'm running out of wall-space!
Product : Great picture from a talented artist, Colours perfectly reproduced on website. Just what I wanted.
I wanted something simple and modern for my new high gloss white and grey kitchen. This is perfect!
I've used ArtGallery before abs their service is always excellent. These latest paintings came quickly and were safely packaged as always.
Guests seeing my original artwork are always surprised that I buy online but they all ask for the web address so I'm converting friends to this way of buying art and supporting talented artists.
I can't recommend ArtGallery highly enough!


Musicians know that it is good to be able to read and play music in all keys.
But music in 5 or 6 sharps or flats is found mainly in exercises written just for training purposes, and is not very rewarding musically. Here's a great piece of solo music - Bach's Partita for Solo Flute bwv 1013 in A minor that I present first in its original key (a minor) and then transposed to g#, Bb, Ab and A# minor (5,6,7,7 sharps or flats) so we can practice in these keys from a masterpiece of solo music.This 4 movement Partita in these keys can be played by violin, and wind instruments.Now playing in 'difficult' keys can be practiced on a piece of great music.


text:
Douglas A. Harrison - US grants
University of Kentucky, Lexington, KY
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Genetic Analysis of Jak Signaling in Drosophila
@ University of Kentucky Research Foundation
Harrison 9723944 The coordinated proliferation and differentiation of distinct cell types is critical to the proper development and maintenance of any multicellular organism. For this coordination to occur, cells must have a means to communicate with one another. The broad long-term objectives of this research are to elucidate mechanisms of cell-cell signaling and to understand how different signals are interpreted to regulate developmental events. Toward these goals, the Janus kinase (JAK) signaling pathway will be studied in Drosophila melanogaster. This system will be used because it is developmentally important, relatively simple, and is conserved between flies and mammals. In mammals, the pathway is know to be comprised of the non-receptor tyrosine kinases (JAKs) and the signal transducers and activators of transcription (STATs). In flies, one JAK (hopscotch) and one STAT (marelle) gene have been recently identified. The genetic and developmental manipulations available in Drosophila make it an ideal model system to further study JAK/STAT signaling. These approaches will complement and extend the biochemical analyses of the pathway conducted in mammalian cells. Mutational analysis has already uncovered a new component of JAK/STAT signaling in Drosophila, unpaired (upd). An understanding of the involvement of upd in JAK signaling is central to the research proposed here. Other molecules integral to the JAK pathway, or that strongly interact with components of the pathway, will be identified and characterized using the genetic tools available in Drosophila. The specific goals of this research are to: 1) Characterize the unpaired locus at the molecular level 2) Determine the functions of the Upd product in JAK signaling 3) Characterize the roles of Upd function in Drosophila development 4) Identify other components of and factors interacting with the JAK pathway
Show summary Hide summary
Analysis of Jak Pathway Activation in Drosophila
Communication between cells is a vital factor in proper development and maintenance of multicellular organisms. The number of molecules that serve as signals is enormous, yet the mechanisms by which cells can respond to signals are much more restricted. A finite number of signaling pathways have emerged as reutilized intracellular signaling cascades that initiate appropriate cellular responses. The long term objectives of this research are to elucidate mechanisms of cellular communication and to understand how different signals are integrated and interpreted to regulate developmental events. One conserved intracellular cascade that has been found in organisms from slime mold to human is the Janus kinase (JAK) signaling pathway. In vertebrates, JAK signaling is the primary mechanism for response of cells to a wide array of cytokines and growth factors. The fruit fly, Drosophila melanogaster, was chosen to study JAK signaling because it uses the JAK pathway in the same manner as humans, yet is amenable to genetic and developmental manipulation. The only known activator of JAK signaling in Drosophila is the Unpaired (Upd) protein. Previously funded research (IBN-9723944) focused on the molecular and biochemical characterization of upd. The Upd protein bears no recognizable similarity to previously identified mammalian proteins, but is similar to a protein from a closely related fruit fly species, Drosophila ananassae. Both Om(1E) and updgenes are found in both of these Drosophila species. Furthermore, the recent release of the Drosophila genome sequence has identified two additional, less conserved predicted proteins that have homology to Upd. The functions of these three new genes will be investigated, as well as the relationships of these genes to upd and to one another. Understanding of the molecules and mechanisms of JAK pathway activation in Drosophila will likely provide insights into developmental signaling in many multicellular organisms. The primary goals of this research are to: (1) characterize, molecularly, biochemically, and phenotypically, the Drosophila melanogaster Om(1E) gene, (2) determine the functional relationships between Om(1E) and upd, (3) characterize, molecularly and phenotypically, two other proteins with homology to Upd, and (4) identify additional components of JAK signaling and related pathways using genetic screens.
Follicular Patterning Directed by Janus Kinase Signaling
A small number of defined signaling pathways have emerged as reutilized intracellular signaling cascades that initiate cellular responses. One of these is the Janus kinase (JAK) signaling pathway. JAK signaling is the primary component of the response of many vertebrate cells to a many cytokines and growth factors. Consequently, the JAK pathway is essential for a many developmental events, including hematopoiesis, immune system development, and general growth. The pathway has been evolutionarily conserved from insects to human. Study of JAK signaling in the fruitfly, Drosophila melanogaster, is particularly attractive because it is amenable to genetic and developmental manipulation and is much simpler than the vertebrate counterpart, with only single representatives of each type of pathway molecule. As in vertebrates, the pathway is critical to many developmental events. Previously funded NSF activities have uncovered a requirement for JAK signaling in the patterning of the follicular epithelium, the monolayer of somatic cells that covers the developing egg and forms the eggshell and specialized structures. The follicular epithelium is comprised of 5 different cell fates that are determined by their position along the anterior-posterior axis The JAK ligand, Upd, as well as a homologous protein, are secreted from the poles of the egg chamber and a gradient of JAK pathway activity is created that is highest at the anterior and posterior termini. The gradient of JAK pathway activity determines the fates of the follicular cells. This suggests that Upd may act as a classical morphogen, a molecule that patterns a field of tissue into different cell fates that are assigned by virtue of position relative to the morphogen source.
The two primary goals of this research will address the hypothesis that Upd may act as a morphogen. First, the mechanisms by which a gradient of JAK pathway activity is established in the follicular epithelium will be determined. The distribution of the Upd and homologous proteins their contributions to activation of the JAK pathway and establishment of epithelial pattern will be assessed. Second, the mechanisms by which the Upd ligand is transported to receiving cells will be examined. Known morphogens are distributed by passive diffusion, active endocytic transport, or a combination of the two. The contributions of these mechanisms to distribution of Upd and homologues will be examined.
The proposed research will be carried out primarily as the major training activity of graduate students. Additional roles will be played by undergraduates seeking learn about biology through conducting independent research projects. As in the past, the majority of students involved in these research activities are likely to be women and/or Kentucky natives. Results of the proposed activities will be presented at professional meetings by the students who carry out the research.
Role of Unpaired3 in Janus Kinase Signaling
The development of multicellular animals from a single-celled fertilized egg is a complex process that requires extensive communication between enormous numbers of cells. It is the long-term goal of this research to better understand how cellular signaling is used to direct activities that sculpt a multicellular organism. The approach taken in this project is to study the mechanisms by which one evolutionarily conserved signal cascade, the Janus kinase (JAK) signaling pathway, regulates development in the fruit fly, Drosophila melanogaster, as a model for developmental cell signaling in other animals, including humans. Study of JAK signaling in fruit flies is particularly attractive because it is amenable to genetic and developmental manipulation and because only the three Unpaired (Upd) family proteins are believed to act as signals for the JAK pathway. Previous studies have examined the developmental functions of Upd and Upd2. The current project will use genetic, developmental, and biochemical methods to determine the functions of Upd3 in development and JAK signaling, as well as to determine the mechanisms by which the Unpaired family proteins act together to regulate JAK signaling during development. It is expected that mechanisms uncovered in this system will be applicable to multi-gene families of cell signaling proteins found in other animals. This project will provide opportunities for the education and training of young biologists and will be the primary training activity of graduate students in the laboratory, with additional roles played by undergraduates seeking to learn about biology through conducting independent research projects.


Tickets for this summer's MTV Crashes Plymouth event will be on sale from Thursday 16 April 2015.
The spectacular live music event, being organised by MTV in collaboration with Plymouth City Council, will take place on Plymouth Hoe on Wednesday 22 July.
It will be followed by a 'Club MTV' night on the same stage on Thursday 23 July, featuring handpicked DJ talent.
Both events will feature a number of headline music acts, which will be announced in the coming weeks.
Tickets for MTV Crashes Plymouth and Club MTV will be available on pre-sale for Plymouth residents living in the PL1 to PL7 and PL9 postcodes from 6pm on Thursday 16 April. Pre-sale tickets can only be booked online through the See Tickets website (search for 'MTV').
Any unsold tickets will go on general sale at 9am on Friday 17 April through the See Tickets website and the box office on 0871 231 0840.
The ticket price for each event is £10, plus a booking fee of £2 and there is a limit of four tickets per person, per event. Under-16s must be accompanied by an adult at both shows. Full terms and conditions are available on the Visit Plymouth website.
Tickets for last year's MTV Crashes Plymouth sold out in 20 minutes.
For more information and the latest updates see the Visit Plymouth website, follow @MTVPlymouth on Twitter or see the What's On Plymouth Facebook page.


text:
Categorie: Grafton Cass – The Cottage in a Cornish Cove
The Cottage in a Cornish Cove by Cass Grafton / #Interview #BlogTour @rararesources @CassGrafton
On 13 februari 2020 6 februari 2020 door elsinGrafton Cass - The Cottage in a Cornish Cove, Q&AEen reactie plaatsen
A heart-warming tale of discovering all you never wanted is exactly what you needed.
Orphaned as a baby and raised by indifferent relatives, much of Anna Redding's happiness as a child came from the long summer holidays spent with an elderly family friend, Aunt Meg, in the quaint village of Polkerran.
With Aunt Meg's passing, Anna is drawn back to the West Country, relocating to the Cornish cove where she was once so happy. Filled with memories, she hopes to perhaps open a B&B—and perhaps cross paths with Alex Tremayne again, a local boy she used to have a major crush on and who only had to walk past Anna to make her heart flutter.
Settling into her new life, and enjoying her work for the older, reclusive and—to be honest—often exasperating Oliver Seymour, Anna is delighted when Alex reappears in Polkerran and sweeps her off her feet.
The stars are finally aligned, but just as Anna thinks all she's ever wished for is within reach, a shock discovery brings everything under threat, and she finds herself living a dream that isn't hers.
Can Anna rescue the new life she has made for herself and, when the testing moment comes, who will be there to hold her hand?
The Cottage in a Cornish Cove is the first in an uplifting series of romances from Cass Grafton. Get to know the locals, wallow in the quaintness of Polkerran, and fall in love with romance all over again.
– When and where do you prefer to write?
I'm a morning person, so I'm usually at my desk by 7.30am, and writing is the first thing I do. I could win medals for procrastination, so I have to try really hard not to get distracted by social media, because then an hour or more disappears in an instant, and I find it harder to settle back into a fictitious world.
If I had a choice, I'd write 'on location'. I did make this a big excuse for taking trips to Cornwall whilst writing this book, and I daren't tell you how many times I stayed in Bath during the writing and research of a couple of other novels set there.
– Do you have a certain ritual?
I'm a dreadful creature of habit! I will be at my desk for about 3-4 hours, by which time I will be feeling the need to take a break. I go for a long walk —weather permitting—and then eat lunch whilst watching the BBC's Bargain Hunt (I love antiques shows).
Then, in the afternoon it will be back to the desk to deal with emails, admin and social media. (This isn't where I confess to playing computer games, is it?).
– Is there a drink of some food that keeps you company while you write?
I drink hot water first thing, but once I've had breakfast I only drink cold water until the evening. I'd love to say I never snack when writing, but I'd be lying. I used to binge-eat M&S Percy Pigs when I was in the UK (I live in Switzerland now). Imagine my delight when I came across a close relation, Fred Ferkel, at our local supermarket in Germany!
– What is your favourite book?
I'm a romance nut but I also love a lot of the classics. Jane Austen has been a huge inspiration and a great influence on my writing. When I was young, Pride & Prejudice was top of the list, but now it's Persuasion.
– Do you consider writing a different genre in the future?
I'm not sure about a different genre, but although I've only written romance so far, I have 'category-hopped'. I started out writing historical romance (Regency, Austen-inspired), moved to writing time-travel romance, and then contemporary upbeat romance with my new release. If anything, I suspect it would be the cosy mystery genre – with romance!
– Do you sometimes base your characters on people you know?
Partially. (looks around guiltily) Don't all writers? Definitely only partially, though, and only ever with a minor character. I've never written anyone who was 100% someone I know… yet.
– Do you take a notebook everywhere in order to write down ideas that pop up?
Yes! I have a range of notebooks in all sizes and styles, most of which were gifts. I love to people-watch, and if I ever find myself without one to hand, I rely on the Notes App on my phone. (Looks around furtively this time). People don't realise you're making notes on what's happening around you if you're tapping into your phone, right?
– Which genre do you not like at all?
I can't read or watch horror stories but, bizarrely, I enjoy a good murder mystery! I love watching Agatha Christie's Marple, the Endeavour, Morse, Lewis series or Midsomer Murders, and I have had phases of binge reading murder mysteries by authors such as Elizabeth George and PD James.
– If you had the chance to co-write a book. Whom would it be with?
I've had some amazing experiences with co-writing!
A few years ago, I was part of a five-author team on a book called The Darcy Brothers. Just imagine, two Mr Darcys in one book!
More recently, I've been co-writing time-travel romance with my friend, Ada Bright. We have two books out so far, through Canelo Escape, where a time-travelling Jane Austen hops between the present day and the past. We have had so much fun writing these funny and heart-warming stories, which are as much about friendship as they are love.
– If you should travel to a foreign country to do research, which one would you chose and why?
Living in Switzerland is perfect for border hopping to another country, so we frequently visit Germany and Austria, and every summer we drive down to Lake Como in Italy. Of all the places we've seen in the last six years here, the Italian Lakes is where I'd love to set a novel. Think of the wonderful excuses you could make because you 'need' to do some research there!
Thank you so much for these lovely questions and the opportunity to be on your blog. I've really enjoyed it and its triggered lots of inspiration. Now, where's that timetable to Como…
Thank you, Cass Grafton and Rachel's Random Resources
An avid bookworm since childhood, Cass Grafton writes the sort of stories she loves to read – heart-warming, character driven and strong on location. Having moved around extensively and lived in three countries, she finds places inspiring and the setting of her novels often becomes as much a part of the story as her characters.
She leans heavily towards the upbeat and insists on a happy ever after. As one of her favourite authors, Jane Austen, once wrote, 'let other pens dwell on guilt and misery'.
Cass loves travelling, words, cats and wine but never in the same glass. She has two grown up children and currently splits her time between Switzerland, where she lives with her husband and imaginary cats, and England, where she lives with her characters.
www.cassandragrafton.com
www.tabbycow.com
https://www.facebook.com/cassie.grafton
@CassGrafton
@cassgraftonauthor
UK – https://www.amazon.co.uk/dp/B083H2Q5V9/
US – https://www.amazon.com/dp/B083H2Q5V9
Kobo – https://www.kobo.com/ch/en/ebook/the-cottage-in-a-cornish-cove
Barnes & Noble Nook – https://www.barnesandnoble.com/w/the-cottage-in-a-cornish-cove-cass-grafton/1135981147?ean=2940163435333
Smashwords – https://www.smashwords.com/books/view/998605


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Magic's players (O'Neal and Hardaway) and Michael Jordan defeated West. Surprisingly, Michael Jordan was named MVP, When Shaq had made 25 points and 10 rebounds.
Michael Jordan returning to the All-Star after the 1993 retirement, made hi first four shots, finishing with 8-11 FG.
He played only 22 minutes (he didn't play in the fourth quarter) and scored 20 points.
David Robinson, who was playing at home, was the best player in the West.
BEST PLAYERS: EAST Shaquille O'Neal 25 points and 10 rebounds, Anfernee Hardaway 7 assists.
WEST David Robinson and Gary Payton 18 points, David Robinson 11 rebounds, Jason Kidd 10 assists.
COACHES: Phil Jackson (East) and George Karl (West).
For the first time in the history of this contest, a white guy could win. The honor went to Brent Barry (Rick Barry' son) who beat Michael Finley in the final with a dunk from the free throws line.
A huge contest by the rookie Tim Legler, allow him to win, maybe in the best contet of the history. The first player with 20 or more points in each round.
For the first time, in 1996, rookies were distributed based in Conference (East - West).
East point guard, Damon Stoudamire, was named MVP, leading his team to the victory.
The best scorer played again in the loser team. This time was Joe Smith. In the West, also played Arvydas Sabonis (the oldest rookie in the history of these games with 31 years), who made 8 points and 3 rebounds in only 4 minutes.
BEST PLAYERS: EAST Damon Stoudamire 19 points and 11 assists, George Zidek 6 rebounds.
WEST Joe Smith 20 points, Bryant Reeves 8 rebounds, Tyu Edney 7 assists.
COACHES: Bob Lanier (East) and Doug Moe (West).


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Ilhan Omar described President Donald Trump's campaign rallies as those of the KKK
Less than half of women participate in labor market: UN
The Louisville Police Department on Tuesday moved to fire two more officers involved in the killing of Breonna Taylor a black woman who died during a botched raid
Hollywood duo Reynolds & McElhenney to seal takeover of Welsh minnows Wrexham
A strong, shallow earthquake has shaken Indonesia's Sulawesi island, causing landslides killing at least seven people and injuring hundreds more in the night
Prime Minister Scott Morrison says Australia needs to be ready for when vaccines have been approved by the Therapeutic Goods Administration
South Australia's Chief Public Health Officer Nicola Spurrier has apologised for wrongly suggesting yesterday that a man breached coronavirus quarantine and put the state at risk
The Economist Magazine debunk Zambia's economic problems
A 15 year old girl has given birth while in the middle of her Grade Nine examinations in Pemba
German Town Goes Into Local Lockdown After Birthday Party Spreader
Azerbaijan to meet OSCE Minsk Group over Karabakh row
WE ARE READY FOR PF SHOULD THEY TOUCH HH
The vice president of the Volta Regional House of Chiefs Togbe Patamia Dzekley has emphasized that the House is apolitical
File photo of military men
The vice president of the Volta Regional House of Chiefs, Togbe Patamia Dzekley has emphasized that the House is apolitical, therefore urging politicians and the general public to desist from tagging them to a particular party.
He stressed that the House operates as an independent body devoid of any interferences.
His comment follows the House's request to the government to withdraw the numerous security personnel deployed in the Volta Region ahead of the December 7 polls.
According to the Volta House of Chiefs, the security presence in the region may suppress votes as tension would be high.
Speaking to Citi News, Togbe Patamia Dzekley noted that their plea to the government to withdraw the security personnel from the region days ago hasn't been attended to.
"The House of Chiefs are an independent body. They should stop profiling us as agents of a particular party. They have not actually addressed the request for the withdrawal of the security personnel. Let me make this issue clear to government and everybody that we do not belong to anybody in this country," he stated.
In September 2020, security personnel were deployed to the Volta region to calm down situations in the wake of the Western Togoland Secessionist attack in the region.
Both chiefs and the opposition NDC called on the government to as a matter of urgency to withdraw the military from the region but their plea was not heard.
Iraqi security forces on Tuesday started to implement its deployment plan in the center of Sinjar district of the northern Nineveh province
Iraqi security forces on Tuesday started to implement its deployment plan in the center of Sinjar district of the northern Nineveh province. "The plan to […]
The street protests by the main opposition National Democratic Congress (NDC) against the results of the 2020 general elections which the party lost
Davies 1 month ago
Robbery suspect pleads guilty to refusing to have fingerprints taken
Africa's coronavirus cases to date now total over 1.8 million according to the latest figures released on Saturday
Decomposing unidentified bodies have been piling up in two cold rooms since 2010 Workers at a mortuary in Pietermaritzburg say bodies are piling up and human organs are not collected
Nigerian Governor Says Army, Not Boko Haram, Ambushed His Convoy
Two more South African ministers test positive for Covid-19


We are are a team of cross-functional product designers and full-stack developers. We are highly versatile, working with a global range of clients on a very diverse mix of product industries. We strategize product development through design thinking methodologies and rapidly develop web and mobile platforms following strict agile processes.
We follow fully transparent best-practice agile and extreme programming methodologies to rapidly create high-quality products that are built for scale.
We turn ideas into full-grown products. We follow user-centric design methodologies with a continuous focus on the highest value-generating features to release to market.
Freshgora is an end-to-end solution for Myanmar shoppers to order food delivered to their doorstep. The Freshgora system covers the full ordering process, assigning orders to available drivers based on location, routes and order sizes.
LeapXpert is a fully secure omni-channel experience for account manager and client communication, portfolio management and trade execution, integrating all major 3rd-party chat applications for a centralised communication experience.
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Q: How to subscribe set event after async from interop dll I want to subscribe event from hEvent, but still dont understand how to subcribe from IntPtr. I searched on web to find tht the way is to use  a delegate. How to subscribe event of such property?
My C# code :
var hEvent = new IntPtr();
IntPtr lpcOmcr = OMCR_OpenDevice(null, ref lpcOption);
uint result = OMCR_TurnonLED(lpcOmcr, (int)ReturnCode.LedColor.OMCR_SET_LED_COLOR_GREEN, ref hEvent); //result = 1 == OMCR_STATUS_PENDING

API Documentation :

Does anyone ever experienced this? Thank you.
Note : This code works to turn on LED.

A: The "event" in this case is not the same as a C# event. It's an unmanaged Windows event handle. All you can do is wait on it. Fortunately, .NET does provide some useful wrappers to let you use one.
The basic way you would handle this is like this:
var hEvent = new IntPtr();
IntPtr lpcOmcr = OMCR_OpenDevice(null, ref lpcOption);
uint result = OMCR_TurnonLED(lpcOmcr, (int)ReturnCode.LedColor.OMCR_SET_LED_COLOR_GREEN, ref hEvent); //result = 1 == OMCR_STATUS_PENDING

using (EventWaitHandle waitEvent =
    new EventWaitHandle(false, EventResetMode.ManualReset))
{
    waitEvent.SafeWaitHandle = new SafeWaitHandle(hEvent, false);
    waitEvent.WaitOne();
}

At least, that should work. Without a complete code example to start with, I can't test the above to make sure it works in your case.
Note that the above is strictly synchronous and of course does not involve a C# event at all. But you can of course take the above basic technique and wrap it in the desired C# abstractions.


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Hays Medical Center > HaysMed News > HaysMed Foundation Sees Leadership Change
HaysMed Foundation Sees Leadership Change
By Gayla Wichman - In HaysMed News - August 27, 2018
Hays, Kan.–After twelve years as the executive director of The HaysMed Foundation, Ruth Heffel has announced her retirement set for August 31. Heffel has guided The Foundation through major growth and established processes that will continue to offer structured expansion opportunities for generations to come. "I have been so blessed with the opportunity to meet and work with exceptionally skilled and dedicated doctors, nurses, and staff at the medical center. Their concern for our patients is truly heartfelt. The Foundation has also been extremely fortunate to have passionate, influential board members whose mission is to help HaysMed thrive. Their work has assisted people of all ages, from newborns to seniors, who have had their health restored here. To them I offer my sincerest thanks," Heffel said.
Stepping into the executive director's office will be Jeff Brull, who joined the team last September as a development officer. Brull has Bachelor of Arts and Master of Science degrees in Communications from Fort Hays State University and served most recently as Advancement Director at Thomas More Prep-Marian Junior-Senior High in Hays. He is married to Julie Brull, and together they have three children. "I am excited by the challenges before us because of the opportunities they represent to serve the region through the work of the HaysMed Foundation. I am passionate about western Kansas and will continue to build on the legacy established under Ruth's leadership through the HaysMed Foundation Board of Directors and the many generous donors and advocates who make life better for us all," said Brull.
The Foundation provides vital philanthropic support to help fund life-saving equipment, special projects and programs for HaysMed that will positively impact the health of our region. Examples include spearheading capital construction projects and vital medical equipment purchases that expand or improve medical services, providing resources for associate improvement through certification and conference opportunities, and by underwriting programs like the annual community flu vaccination drive, community CPR training, scholarships, and more.
The Foundation is a non-profit 501(c)(3) charitable organization dedicated to support, assist and promote the interest and welfare of Hays Medical Center, its programs and activities. The Foundation is staffed by Development Officer Jayne Inlow and Operations and Data Coordinator Jana Fross, and is governed by an eighteen member board of community volunteers
Tags: hays, hays medical center, hays medical center foundation, haysmed, health, healthcare
← HaysMed Recognizes 2018 First Quarter Patient Satisfaction Award Winners
HaysMed Wound Healing and Hyperbaric Center Brings Attention to Peripheral Arterial Disease (PAD) Awareness Month in September →


Take the A8 motorway, exit "St ISIDORE/DIGNE". Then take the RN202 (after about 17 miles). Then turn right on the D2205 in the direction of ST SAUVEUR SUR TINEE and ST ETIENNE DE TINEE to ISOLA Village. In the village, turn right onto the D97 all the way to ISOLA 2000. (NICE - ISOLA: 55 miles).
Then take a taxi, bus or rent a car.
NICE COTE D'AZUR International Airport. Then helicopter (25 mins.), taxi or bus from the airport.
At just 90 km from Nice, Isola 2000 is scenically located beneath the southern sun. In summer, the resort makes full use of its charms of seduction.
Resort altitude: 1800 to 2000 m.
A tree-top adventure trail, canyoning in the valleys surrounding the resort, 600 km of signposted trails to explore the wonderful flora and fauna.
Abundant wild fauna with ibexes and chamois, Eurasian black grouses and big birds of prey such as the golden eagle.
To catch sight of the wildlife, your undivided attention and discretion are essential.
Flora unique to Europe with over 2,000 plant species. 220 are considered very rare and 40 native to the region.
Resort description for information only (subject to change).
Groups consisting of minors are only allowed when accompanied by an adult (minimum of one adult per apartment). We reserve the right to refuse entry if no adult is present.
At the heart of the resort, the apartments are situated close to the shops and restaurants.
Fully equipped kitchenette with electric hobs, fridge and dishwasher. Mini oven or oven in two-room apartments or bigger and microwave in four-room apartments for 9 people. Bath or shower room and WC (separate in some apartments).
Bunk beds in hallway/recess. Living room with pull-out bed.
Living area with pull-out bed, double living area with pull-out bed (sliding partition), recess with bunk beds.
Hallway with shower room and WC. Bedroom with bunk beds, from this bedroom there is access to a second bedroom with double bed and a living area with twin beds. From the living area access to a second bathroom and WC and bedroom with double bed.
Living room with pull-out bed. Bathroom with WC.
Upper level: bedroom with double bed and mezzanine (open on to lower level) with bunk beds. Sink + WC. Dressing area in most apartments.
Entranceway with 1 single bed. Living room with pull-out bed. Bathroom with WC.
On the upper level, bedroom with double bed and mezzanine with bunk beds. Sink and WC.
Living room with pull-out bed. Kitchenette.
Upper level: bedroom with double bed + 1 single bed and 2 bedrooms with twin beds in each.
All descriptions are for information only and are not contractual.
Cleaning: the apartment must be vacated clean and tidy (cleaned, washing up done, bins emptied, linen folded).
If not, cleaning service will be charged (Studio/€40 - 2 rooms/€46 - 3 rooms/€59 - 4 rooms and duplex/€69).
Disabled facilities: 6 studios are the same size as 6-person apartments with higher WCs and grab rails in the bath.
Holiday tax to pay on site according to current rates.
€200 deposit to pay on site.


text:
HP's Unix base offered Opteron carrot
Come for a stroll in the Sun
By Ashlee Vance 17 Aug 2004 at 13:18
SHARE ▼
HP World Sun Microsystems has started Phase III of its HP Away program for shifting customers off the Tru64 and HP-UX operating systems and onto Solaris.
This time round Sun has centered its attack on a new fleet of Opteron servers, which were finally delivered in July, instead of its traditional UltraSPARC-based gear. As in the past, Sun offers up free consulting services to HP customers to demonstrate how much a move from Tru64 or HP-UX will cost and how well applications will perform on Solaris. Over the past year, Sun has pulled 150 customers from HP, resulting in close to $200m in revenue.
"We were focused on moving customers from RISC to RISC before, but now that we have these Opteron systems, we decided to offer a move from HP RISC platforms to x86 as well," said Larry Singer, Sun's head of global market strategies.
One positive with the new Opteron program is that HP customers are being given a path from traditionally more expensive Alpha- and PA-RISC-based servers to lower-cost x86 gear. Sun offers workstations, a two processor box and a four processor box based on AMD's x86-64-bit Opteron chip. Sun is familiar with this shift from RISC to x86, as it has seen a number of its key customers, particularly those in the financial services markets, move from Solaris/SPARC kit to Linux on Intel.
These days, however, Sun's renewed interest in Solaris x86 has it asking HP's customer base to make an easier Unix to Unix shift and just replace the processor underneath the OS. But with only up to a four-processor Opteron system available, Sun won't be able to tempt HP's higher-end Unix customers to make this move. In addition, Sun has yet to complete a 64-bit version of Solaris for Opteron. HP customers would need to be running 32-bit software or wait until December to get the 64-bit OS.
Sun, of course, started this HP Away program to attract Alpha and PA-RISC customers that are being forced to move onto Intel's 64-bit Itanium processor, as HP pulls out of the processor-making game.
"We think IBM and Sun are duking it out for the cadaver of HP's business," Singer said.
Sun has promoted its Opteron line as an option for HP customers in the past. Earlier this year, Sun said its two-processor V20z server was a valid choice for the HP Away program. Now, however, that Sun has fleshed out its Opteron line, it is making a bigger deal of the kit. The HP World conference being held here this week also clearly played a role in the timing of Sun's latest HP Away announcement.
Still, Sun only expects about one-third of the HP customers to pick Opteron over UltraSPARC, as the RISC to RISC move is a more natural choice.
Sun last year started Phase I of the program focusing on Compaq's Tru64 customers only and then later targeted HP-UX customers in Phase II.
At the HP World event yesterday, an HP Unix executive was heard in the press room describing Sun's promotion of Solaris x86 as "bullshit" and later "crap". The exec insisted that Solaris x86 would only have a future if it was ported to Itanium in which case it would have to be Solaris EPIC, it seems. He also suggested that customers no longer trust Sun with the Solaris x86 support after it flip-flopped on support and development of the product a couple years back, which is certainly true to some degree. That said, it seems doubtful that Sun's Unix future will be governed by Itanic, since Sun currently moves more UltraSPARC-based systems in a couple of weeks than all of the Itanium servers HP ships in a year. ®
HP goes after UK Sun clan
Sun offers a hand to confused HP-UX customers
Sun ups its Tru64 temptation
Sun hits back at HP's migration offers
Sun Microsystems: big fish, shrinking pond
IBM, Sun and HP locked in giant Unix OS spat
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Sirisha is a Senior Project Manager with 16 years of transportation planning and engineering experience. Proven ability to balance and prioritize multiple high-level projects. Effective leader with winning track record on several corridor studies, design-build proposals, IAJRs, traffic and planning pursuits. Extensive experience in travel demand modeling and simulation modeling for multimodal projects all through Texas and Midwest. Successful in pursuit management and client relations for several industry clients.