text:
Bianca Montgomery
MONTGOMERY, Bianca Christine
Portrayed by: Jessica Leigh Falborn (1988-90); Caroline Wilde (1990-91); Lacey Chabert (1992-93); Gina Gallagher (1993-97); Nathalie Paulding (1998); Eden Riegel (2000-05, 2005, 2006-07, 2007, 2008-present)
Family: Erica Kane (Mother); Travis Montgomery (Father); Kendall Hart (Sister); Molly Montgomery (Sister); Matthew Sean Montgomery (Brother); Miranda Montgomery (Daughter); Gabrielle Montgomery (Daughter)
Marriages: None
1988: Bianca Christine Montgomery was the light of her parents, Erica Kane and Travis Montgomery's, life. Before she was even one year old, she would almost die during delivery, recover from a nearly fatal gunshot wound, and escape kidnap and ransom attempt.
1990: Bianca returned from a trip from Disneyworld deafly ill. She was diagnosed with Reyes Syndrome. The sight of her parents back together helped her to recover. After Bianca was released from the hospital, Erica and Travis remarried for her sake.
1991: Bianca caught Jack and Erica in bed together. She decided she wanted to burn down the dollhouse her uncle had given her. Only, the fire spread, and her room was engulfed in flames. This event would spark Travis' custody suit. Based on Bianca's testimony, Travis won full custody.
Travis made plans to move to Seattle. Bianca worried about what the distance would mean for her relationship with her mother. Erica assured Bianca that no matter where she was, she would always be her mother.
1993: Bianca fell off a horse while riding in Wildwind. Kendall Hart became jealous of all the attention Erica paid her. Kendall revealed a startling secret: she was Erica's daughter too. Mona united all the Kane women in time for Erica's marriage to Dimitri.
1994: Bianca returned to Pine Valley to support her mother as she went to trial for almost killing Dimitri. At the trial, Kendall brought Richard Fields, her mother's rapists. When Fields tried to molest Bianca, Kendall realized the wrong of her ways. She exonerated her mother, and went to prison for perjury. Dimitri and Erica reunited.
Tragedy struck Bianca's life when Mona died. This was the first time in Bianca's life that she had to deal with the death of a loved one. She was so distraught that she could not even finish her part of the eulogy.
1996: Bianca was the victim of a failed kidnapping attempt by Dr. Jonathan Kinder. In the struggle at the Linden House, Jonathan slipped and fell down a flight of stairs, seemingly to his death.
1998: Bianca ran away from home to be with Erica, who was serving time for the kidnapping of Madelyn Grey. Travis had forbid his daughter from seeing her mother. Bianca began acting out, refusing to eat until she could see Erica. Bianca's eating disorder became full blown anorexia. Travis and Barbara did their best to convince Bianca to eat. But, it only Erica was able to get through to her daughter. After an intervention, Bianca agreed to check into a clinic for her recovery.
2000: Bianca came back to Pine Valley a changed woman. Erica chalked up Bianca's erratic behavior to her time at the anorexia clinic. Bianca confided in her new friend, Erica's houseguest Leo duPres, something much different. Bianca was a lesbian. She did not know how to come to terms with her sexuality and her mother's expectations of her.
Bianca's visit in Pine Valley became a permanent arrangement when Travis suffered a massive stroke in Seattle. Bianca was devastated by her father's death.
Bianca became distraught when she learned her friend Sarah was set to marry someone in New York. Bianca fell in love with Sarah at the clinic. Erica finally confronted Bianca about why she was acting so erratically. Bianca admitted the truth to Erica. Erica could not accept what Bianca was saying. Bianca turned to Myrtle and Jack.
Erica became uncomfortable with Bianca's closeness to Laura English. Though Bianca was wanted something more, Laura was just her friend. Laura almost drowned after being thrown overboard from Adam's yacht, Fidelity. Bianca witnessed Greenlee Smythe as the culprit. Greenlee threatened to out Bianca to everyone if she told anyone what she saw. Bianca confided the truth in Leo.
2001: Sarah made it back to Pine Valley to see Bianca. Bianca could see Sarah was not eating again. By confronting Sarah's problem, Bianca was forced to deal with her own eating disorder. Bianca overheard Erica fighting with Sarah's mother in the hospital hallway. Erica could note believe Mrs. Livingston was going to leave Sarah in her time of need. Bianca realized Erica still loved her.
Bianca met Frankie Stone after she tried to con Erica with a fake car accident. Bianca thought she was able to see through Frankie's lies. Secretly, she had a crush on Frankie. She began dating Frankie much to Erica's chagrin. Soon she saw Frankie's real colors. She caught Frankie in bed with a high JR Chandler. When Bianca told Erica what happened she told her she was going to kill Frankie for hurting her. The next morning, Frankie was found dead.
2002: Bianca had blocked out her memories of the night of Frankie's death. Kendall returned to town and alleged that Erica had made plans with her to skip town if she was found guilty. Bianca sided with Kendall during the trial until she found out the whole story was a lie to hurt Erica.
Frankie's twin sister, Maggie Stone, came to Pine Valley determined to find out who killed her sister. Together, they found out Vanessa Cortlandt, the drug lord Proteus, had killed Frankie after she learned the truth about her identity. Bianca forged a relationship with her new friend, and attempted to make amends with her mother.
Bianca had feelings for Maggie, but was afraid she was just replacing Frankie for her. She arranged for Maggie to start dating Tim Dillon. Maggie humored Bianca, but the relationship still fizzled. Maggie and Bianca had to pull together after Leo was presumed dead after an accident at Miller Falls.
To Erica's surprise, Bianca asked to begin working at Enchantment after graduating high school.
2003: Bianca fit in perfectly at Enchantment. Her closest friend was chemist Boyd Larraby. Boyd had a crush on new finance officer, Lena Kundera. Bianca did not know how to break it to Boyd, but she knew Lena was gay. They entered into a friendly wager about who could seduce Lena first. Bianca won.
Lena was discovered to be a mole that was placed in Enchantment by Michael Cambias to uncover Boyd's secret anti-aging cream formula. Bianca confronted Lena about her lies. Lena admitted to lying to everyone at Enchantment, but assured Bianca her feelings for her were true. Lena pulled Bianca in for a kiss. At that moment, the authorities arrived, and Lena was taken into custody for larceny.
Bianca had arrived how at the Boarding House where she found Michael waiting for her, Michael was furious that Lena had ratted on him, and that Kendall had turned him into the authorities. Michael took out his aggression on Bianca, by raping her. Bianca was destroyed by the violation. Knowing how her mother's rape affected her, Bianca did not want to burden Erica with the truth. Instead, she destroyed all the evidence of the night.
Bianca tried to cope with the trauma, but could not do it alone. She began to push everyone away, including Lena. Maggie knew something was wrong and reached out to Bianca. Maggie helped Bianca cope and come to the realization that she needed help. She finally broke down and told Erica what had happened. Jack made it his duty to see Michael pay for what he had done.
Since Bianca had destroyed all the evidence of the rape, Michael was not indicted for the rape. At the same time, Bianca learned she was pregnant with Michael's child. Kendall came up with a plan to adopt the child so that Bianca would not have to go through an abortion, or deal with Erica's pressure to get rid of the baby. Bianca felt guilt over the fact that the ruse pushed Kendall and Erica further apart. But she did not want to make a child suffer for her father's sins. David agreed to treat Bianca at the clinic, under the named "Frankie Stone" so that Erica would not find out.
Michael was found dead in a meat locker. Kendall went to trial for the murder.
2004: Kendall's fake pregnancy was revealed at trial. Bianca was forced to tell Erica she had not aborted Michael's child. Bianca realized that she had murdered Michael. She blocked the evening out of her mind. She was found to be acting in self-defense and found not guilty as a result.
Bianca began to make plans for her daughter's birth. But Erica has not reacted to the news well. Distraught over Erica's rejection of her child, she went driving in a storm. Her friend, Babe Chandler, accompanied her. They were stranded, and soon both pregnant women went into labor. Bianca held her daughter, Miranda Montgomery in her arms before passing out from loss of blood.
When she awoke from her coma, Kendall had devastating news. Miranda died in the helicopter rescue. Bianca lashed out against Erica and blamed her for Miranda's death. When she heard the cries of Babe's daughter, Bess Chandler, she was sure it was Miranda. She kidnapped Bess and took her home. Ryan and Kendall arrived to retrieve her. Bianca needed to realize her child was really gone.
Erica had run away to Las Vegas. There, she sunk into alcoholism. Jackson recognized what had happened and staged an intervention. Erica finally admitted to the truth about her rape. Her father had given her to Fields so that he would agree to star in his next movie. Acknowledging what had happened finally made it possible for Erica to deal with Bianca's rape, and Kendall's presence.
Lena left Pine Valley to attend to her sick mother in Poland. Though Lena gave her a promise ring, the strain from their distance soon lead to the end of their relationship. At the same time, Maggie had become very close to Bianca.
Ethan Ramsey came to Pine Valley claiming to be the son of the late Alexander Cambias, II, and rightful heir to the Cambias Estate. Bianca offered Ethan the shirt she wore when Miranda was born for DNA testing. But, Jonathan Lavery had stolen the shirt and destroyed it so that Ryan Lavery would remain the true heir. Maggie, who was now dating Jonathan, had witnessed Jonathan in the act, but kept the truth from Bianca.
Babe and Jamie Martin went on the run after learning JR had caused Babe to overdose on pills. Babe made contact with Bianca. She had thought it was to help her kidnap Bess, who Bianca thought was better off away from JR. When Babe and Bianca reunited, Babe had a bombshell for her: Bess was Miranda. Paul Cramer, the helicopter pilot who had rescued them, switched Miranda and Babe's son, Ace Buchanan, at birth. Bianca lashed out at Babe for lying to her for so long. When JR arrived, he refused to give Bianca her baby. In a struggle for Miranda, Bianca lost her footing and fell off a landing.
Bianca was rushed back to Pine Valley in a coma. The only thing that could save her was a reunion with her child. Erica coxed Adam into agreeing to a DNA test. On Christmas Eve, Erica rushed her newfound granddaughter to Bianca's bedside. Holding Miranda in her arms was enough to bring her back to consciousness.
2005: Nick and Mark visited Bianca to meet the newest member of the Kane clan. Mona had given Nick a letter to be given to Bianca when she had her first child. It was her sage advice on how to raise a Kane child.
Bianca learned Jonathan Lavery was abusing Maggie. Jonathan harbored animosity towards Bianca because Ryan signed over the Cambias Estate to Miranda. Bianca convinced Maggie to leave Jonathan. She admitted her feelings to Maggie again.
JR tracked down Babe, and a custody battle began over their child, Adam Chandler, III. Bianca surprised everyone by speaking out on behalf of Babe.
Bianca made plans to leave Pine Valley and work at Cambias Headquarters in Paris. She promised to be back for her mother and Uncle Jack's wedding. The plane was delayed because of fog. It gave Maggie enough time to stow away on the flight. She wanted to go to Paris to be with Bianca.
Bianca, Maggie and Miranda began their lives together in Paris. Bianca did attend Jack & Erica's wedding, but she brought an unwanted guest: Ethan. Kendall had broken up with Ethan because he lied about who killed Edmund Grey.
Bianca would make another visit at Christmas time. Kendall was pregnant with Ryan's child and struggled with her decision to keep her child. Bianca helped her sister through the trying time, just like Kendall had done for her before.
2006: Upon learning Kendall was in a coma, Bianca rushed back to Pine Valley. Luckily, Kendall recovered. Bianca and Miranda met the newest member of the Kane family, Spike Lavery.
Bianca's next trip to Pine Valley was a more permanent arrangement. Bianca had discovered Maggie kissing another woman. Bianca also wanted to help her family deal with some major changes. Her brother, Sean, moved in with Jack because Barbara was traveling Europe with her new boyfriend. She also learned she had another brother, Josh Madden. Josh was Erica's son with her first husband, Jeff Martin. Josh had done a lot of things to hurt members of her family, but Bianca was willing to give him another chance.
While working at FUSION, Bianca met eccentric pop star, Zarf. Zarf had an unrequited crush on Bianca. Bianca tried to explain she was not interested in men. On New Year's Eve, Zarf invited Bianca on a date. That night, he revealed his true identity: Zoe, a transgender lesbian.
2007: Bianca worried for Kendall, who was one of the targets of the Satin Slayer serial killer for her affiliation with FUSION. Many in town wrongfully suspected Zoe to be the killer because of her eccentric behavior. Babe and Bianca believed Zoe's innocence. As Miranda befriended Zoe, Bianca began to see her in a different light too.
Maggie returned to Pine Valley and begged Bianca to return to Paris, away from the serial killer's reign of terror. But Bianca had not forgiven Maggie yet. Maggie decided to stay to protect Bianca, but she kept her at arms' length. Maggie got the point, and left for Paris alone.
Alexander Cambias, sr. was arrested when he was revealed to be the Satin Slayer. Bianca committed herself to helping FUSION re-launch. She enjoyed working with Kendall, and her newfound brother, Josh Madden.
It was Barbara's visit that left Bianca unsettled. Bianca revealed Barbara had refused to let her visit Molly and Sean after coming out of the closet. Barbara tried to make amends by giving Miranda a birthday gift from Travis. It was Bianca and Babe's first chance to share a birthday with their children.
Bianca stood by Zoe as she came to terms with her identity. After her public outing on New Beginnings, Zoe decided to return to London and re-launch her career as a female artist. Erica encouraged Bianca to return to Paris and confront her problems. Zoe and Bianca remained close.
Bianca came back to Pine Valley for the holidays and to meet her new nephew, Ian Slater. Bianca revealed she and Zoe had drifted apart. Bianca was looking for someone to be a part of her family with Miranda, and Zoe's lifestyle did not fit the bill.
2008: Bianca returned to Pine Valley the right a tornado destroyed most of the town. She arrived at Zach and Kendall's beach house moments before the funnel clouds touched down. She had a surprise for Kendall: she was pregnant. She had asked Zach for a sperm donation so that her new child would be closely related to Miranda. Before Bianca could tell Kendall, the ceiling of the beach house caved in on her. Kendall was left in a coma.
Zach arrived to the site of debris. He did not know Bianca was pregnant either. That night, Bianca went into labor in the ruins of the Slater home. She gave birth to Gabrielle Montgomery.
Bianca was in a serious relationship with architect Reese Williams. Reese brought Miranda back to Pine Valley as soon as she could. She asked Bianca to marry her. They were going to raise Gabrielle together. Erica quickly got on her way planning their wedding. Reese and Bianca agreed to stay in Pine Valley to help Zach with Kendall's kids.
Bianca became uncomfortable with Reese and Zach's closeness as they worked on rebuilding The Season's East casino. On Christmas Eve, Reese's ex-fiancé paid Bianca a visit. Bianca was shocked to learn Reese was going to marry a man, Simon.


There's nothing we like more than a challenge. If you're looking for something out of the ordinary or have an idea that's a little off the wall, then let's grab a coffee.
We're passionate about what we do and have a LONG list of ways we think we could help you, many of which you don't have time to hear about now. We love the weird and the wonderful and have been involved in lots of fun projects that really push the boundaries of marketing.
We're certain we can do the same for you and your next big idea.


On our return from Jordan, I had a lovely surprise in the post. A box came through the letterbox containing the most spectacular bunch of flowers.
Yes, really - those flowers were beautifully packed, complete with advice and ideas of how to arrange them and over the next few days, every single one bloomed beautifully. (Thank you, Amy!) A splash of colour in what has been a pretty grey world these last few days.
For February really is a dreary month, isn't it? Once the snow had gone, we were left with damp, foggy days and the brief moments of sunshine were few and far between.
We've been undecided about whether the "snow day" chocolate cake was really worth the huge quantity of chocolate and the effort of making it.
It was so enormous that a few friends and neighbours were needed to help out.
These dreary days are a good opportunity to restock the freezer, though.
To make some lovely scented candles from a kit given to me at Christmas.
To have a go at something different.
and to put together some little packets of fun for small friends.
The mornings have been cold and dark but I come home warm and refreshed - my book group read this month confirmed my own thoughts about the joy of swimming, too.
Two weeks after those flowers came through my letterbox, they are still looking gorgeous! I've weeded out a couple of brown petals but will wholeheartedly recommend Bloom and Wild - I think this was their Piper collection.
Lovely as they are - still - I couldn't resist an 85p bunch of daffs to put in a jug on the table.
February days at home. What's not to love?


Add a workshop to enhance your educational experience.
We have workshops for PMAs, too!
You'll find a myriad of industry resources at our full Exhibit Hall.
Welcome to The Western - your go-to meeting and exhibition for podiatric medical professionals! Gain valuable knowledge, engage vendors, and earn CEs along the way.
The Western is fast-approaching, and booth reservations in our sell-out exhibit hall are underway. Don't miss out! Apply for booth space and save your spot at the best podiatric medical meeting in the West today.


I am not as innocent as my self-righteousness suggests.
This entry was posted in 108 thoughts, reflections and tagged 108Buddhas, enso. Bookmark the permalink.
That's good to know. I'm not as self-righteous as my innocence suggests.


Blend dates, cashews and desiccated coconut in a food processor, until the consistency resembles a crumbly paste.
Add lemon peel and juice, vanilla extract and salt. Blitz to combine.
Roll into walnut-sized balls, and roll in desiccated coconut to coat.


Tuna is what's for dinner these days at my house these days. Tuna is cheap, easy to keep on the shelf and healthy because it's packed with protein and fish oil. If you are turned off by the strong smell or flavor of tuna, I encourage you to give it another try with some of the recipes below and you will be impressed with how yummy it is incorporated into these dishes. Here are 5 healthy tuna meals with Weight Watchers Smart Points.
When it comes to the Weight Watchers program, you can't go wrong with tuna. Six ounces of protein-packed tuna is only 1 point and 8 ounces is only 2 points, making it a real points bargain. Be sure you purchase the kind packed in water, not oil.
What healthy tuna recipes do you enjoy?
Which Journaling Bible is Best for You?
I like tuna salad made with miracle whip. 1 tbs of miracle whip is 1 point.


text:
"""Script to compare netcdf files"""

from improver import cli
from improver.constants import DEFAULT_TOLERANCE

@cli.clizefy
def process(
    actual: cli.inputpath,
    desired: cli.inputpath,
    rtol: float = DEFAULT_TOLERANCE,
    atol: float = DEFAULT_TOLERANCE,
    *,
    ignored_attributes: cli.comma_separated_list = None,
) -> None:
    """
    Compare two netcdf files

    Args:
        actual:
            Path to output data netcdf file
        desired:
            Path to desired/known good data netcdf file
        rtol:
            Relative tolerance for data in variables
        atol:
            Absolute tolerance for data in variables
        ignored_attributes:
            List of attributes to ignore in the comparison. This option allows for
            attributes such as "history" to be ignored, where such attributes often
            vary between files without indicating any differences in the data.

    Returns:
        None
    """
    from improver.utilities import compare

    compare.compare_netcdfs(
        actual,
        desired,
        rtol=rtol,
        atol=atol,
        ignored_attributes=ignored_attributes,
        reporter=print,
    )

redpajama_set_name: RedPajamaGithub


text:
Republican in the White House in 2016?
by James Hoover / March 18th, 2015
In spite of its extremism, two factors will assure a more competitive GOP in the 2016 presidential election. First is the GOP's unified effort to appear less radical in the public's eye. Second is the belief of Democrats, especially the Hillary crowd, of their advantage due to presidential elections which sport more young and minority voters. Related to this, Hillary's current strength among the base puts off progressive challengers like Elizabeth Warren.
The first is evidenced by the popularity of Scott Walker in New Hampshire, not a known quantity nationwide, certainly not known for his Wisconsin anti-labor, pro-business stance. He evades right-wing snafus, such as Todd Akin's comments on "legitimate rape" in 2012.
Like most Republican candidates for president in 2016, he clearly refuses to be drawn into statements that will openly label him as radical, basic gotcha questions like torture, evolution and birth control. For example, speaking at the Chatham House foreign Policy think tank in London, where Walker hoped to establish foreign policy credentials, he was asked, "Are you comfortable with the idea of evolution? Do you believe in it?" "I am going to punt on that one," he said.
The Conservative Political Action Conference (CPAC), held recently, also signaled Republican unity in portraying moderation. It welcomed all likely GOP presidential candidates, including Jeb Bush, who is considered more moderate. Knowing some threatened to boycott his speech, Jeb brought his own cheering section. Radicals like Sarah Palin even toned down her extremist rhetoric with more lucidity and less vitriol, speaking of veterans and PTSD. Ted Cruz showed conservative propriety by framing gay marriage as a states'-rights issue rather than moral. Usually showing more vitriol at past CPACs, the CPAC conference was almost gentlemanly with no hate-mongered signs like "No Muslims = No Terrorists" seen during George W. Bush times.
The second factor eliciting warning signs for Democrats and Hillary Clinton is more complicated. Hillary is more jingoistic than the progressives in the party, something which currently suits the American majority's view about ISIL, but she owes allegiance to Wall Street, and like establishment Democrats, seems unable to deliver on serving the working class.
There is still unrest among Americans regarding stunted progress for the middle class. Too many liberals have let conservative talking points guide their discussion about the wage growth problem: workers don't have the education or skills required for high-tech jobs; robots and globalization are taking all the jobs, leaving workers behind. Voters are not really interested in buying such excuses that, in effect, blame the workers. The real cause of stymied wages is embedded in the political and corporate system.
The stagnation of wages is actually a thirty-five-year story, one which both parties let happen. We all know that the focus has been on the so-called makers during that period of time. Conservative forces – both parties — have made sure that corporate profit and stockholders are the focal points. Corporations plow back profits into executive salaries and stockholder dividends, not into labor, and compared to the past (before 1980), not into capital. Why replace cheap labor with robotics? And overall, corporate structure has shifted risk down to workers with contingent contracts, stingier retirement benefits, less generous franchise models, and plentiful subcontracting agreements. The laser focus on profits means most going to the top and less to the bottom.
It's no surprise that government policy helps drive wage stagnation too. Conservatives talk endlessly about the free market, but our economy is shaped and driven by government policies that work for business and against the worker. For example, where are the people opportunities when college students must accumulate over a trillion dollars in debt to get a college education? Even health care is corporate-centered with the failure of Congress to allow bargaining with Pharma for better drug prices and Obama's ACA being the Republican profit-centered healthcare model.
The real value of the minimum wage has fallen about 33% since 1968. Union membership was cut in half over the past 30 years, from 20% to 10%. Unions used to bolster wages and benefits for union and non-union workers alike. The way government structures markets has weakened labor and caused wages to stay stuck. For this, we need to look toward Congress and the President, but we can also see the bias against workers in other institutions, whether the Federal Reserve Bank, the media, or the court system – something the power system put together over the last thirty years.
The Federal Reserve policy has overseen an unemployment rate of over 6% for over 6 years, consistently attacking inflation, which is worrisome for corporations, rather than unemployment. GOP obstruction and its budget constraints have kept government funding so low that there are 500,000 fewer government workers since 2008. Courts have consistently ruled in favor of corporations, regarding bankruptcy, healthcare benefits, unions, and consumer litigation against corporations.
The warning signs are there if candidate care to see them. The public is not happy with either political party or with government in general. A recent Gallup poll asking, "What do you think is the most important problem facing this country today?" Eighteen percent say "government." Eleven percent say "the economy." Ten percent say "unemployment." Seven percent say "immigration," and the same percentage say "healthcare." Other issues register less than seven percent. Another recent Gallup poll gives neither political party a 40% favorability rating.
With only two parties providing candidates in the 2016 Presidential election, Republicans, in spite of their extremism demonstrated in the past, could prevail. If the Republican candidate can appear more moderate than the party actually leans and is less known for extremism, like Scot Walker in Wisconsin, for example, and if Hillary Clinton does run and continues the Clinton – Bill and Hillary – allegiance to corporate interests and perfunctory middle class support – what we have seen, in effect, during the Obama and Bill Clinton tenure — the tide could well swing Republican.
With Hillary, we saw pro-worker rhetoric in 2007, during the 2008 presidential primary, but as we said, wage stagnation has been going on for some thirty years. The middle class will want more in 2016.
James Hoover is a recently retired systems engineer. He has advanced degrees in Economics and English. Prior to his aerospace career, he taught high school, and he has also taught college courses. He recently published a science fiction novel called Extraordinary Visitors and writes political columns on several websites. Read other articles by James.
This article was posted on Wednesday, March 18th, 2015 at 8:12am and is filed under Democrats.

redpajama_set_name: RedPajamaCommonCrawl


text:
Game QA
Game Art Services
10 Best Upcoming Indie Games To Keep On Your Checklist
Looking through these upcoming indie games is overwhelming!
There are many interesting, mysterious, and gorgeous games to watch. Each game is equally ambitious in meeting its goal.
1. RAPTOR BOYFRIEND: A HIGH SCHOOL ROMANCE
The game Raptor Boyfriend developed by Rocket Adrift, is A High School Romance. The game is all about a shy, awkward teenager looking for love in the 1990s. It's a dating simulator and visual novel game. In this game, the players or the main character Stella make friends with many cryptid teens who are a fairy, a talking velociraptor, and a bigfoot. The game looks like a 90's teen drama, and it's got everything from dramatic phone calls, make-out sessions, and recording tapes. The art style looks incredible, too.
2. SATURNALIA
Saturnalia is a fashionable survival horror game issued by the Epic Games Store in 2021. The gameplay takes place in Sardinia, Italy, in 1989, in an old village with a bizarre ritual, and people disappear each year. However, what stands out most is Saturnalia's art style. You haven't seen anything like it!
3. SHE DREAMS ELSEWHERE
As you may have guessed, the gameplay takes place within a dream. It's a roleplaying adventure game. This indie game has a surrealist vibe with the perfect setting for a bad dream. Likewise, the music, composed by Mimi Page, is excellent. She Dreams Elsewhere will release on Mac, Windows PC, Nintendo Switch, and Xbox consoles in 2021.
4. GOODBYE VOLCANO HIGH
Canadian developer KO_OP is developing Goodbye Volcano Height. It is a narrative game about some high school-aged dinosaurs. They're figuring out life with graduation approaching. The game is designed as a cinematic game all about the end of an era and the beginning of a love story. Goodbye Volcano High is getting released on PlayStation 4 & 5 and Windows PC in 2021.
5. SEASON
This game was announced at the Game Awards 2020, and developer Scavengers Studio developed it. It was one of the exceptional games from the awards night. The game features a woman accumulating memories of a beautiful, mysterious world. The game is coming in 2021.
6. CHINATOWN DETECTIVE AGENCY
Sure, we've got an enormous cyberpunk video game out at the end of 2020. But there is more extra to the genre, and you can witness that in Chinatown Detective Agency. The gameplay takes place in 2032 in a stylish and modern Singapore. The game is created by Singapore-based developer General Interactive Co. and looks like an exciting future and it's coming in 2021.
7. VENBA
From developer Visai Games, Venba is a "narrative cooking game" set in 1980s Canada. The game focuses on an Indian mother, with gamers tasked with cooking and retrieving lost recipes. It's a story about a family filled with love and much more. This indie games trailer looks incredible, and the game will be out this year.
8. SKATEBIRD
The game Tony Hawk Pro Skater 1 + 2 held me off for a while, but the skateboarding game I'm looking forward to is SkateBird, from developer Glass Bottom Games. Birds on skateboards! Birds! On! Skateboards! You can checklist the game on Steam now. The game is getting released on Nintendo Switch and others consoles.
9. CHAOTIC ERA
From developer BOBBY, Chaotic Era looks super ultra-modern. It is a black-and-white interstellar, real-time strategy game. The developer mentioned that player will take on the role of a hyper-advanced AI system created by one of humanity's most significant (and now extinct) megacorporations. You should land Earth's last escape ship on a new world and rebuild human civilization from the ground up in the game. It's coming to Apple iOS devices.
10. BOOK OF TRAVELS
Developer Might and Delight developed the game. They describe Book of Travels as a "unique social roleplaying adventure that doesn't hold your hand." It's designed in a fairytale world that's open for exploration," where the player creates their journey. It's curious to see how the multiplayer factors play out when this gets released for Windows PC this year.
11. DORDOGNE
The one word to describe Dordogne is stunning. The game has a fantastic watercolor style that anyone will instantly draw to. According to the Steam page, this narrative adventure game has the player engaging in her childhood memories to solve puzzles. Of course, the gameplay is in the present, and the past, but both worlds look gorgeous. It was released for Windows PC in 2021.
12. TEACUP
The character in the game, Teacup is a very shy frog. But, the whimsical world is filled with other animals to meet and plenty of puzzles to solve. It has an incredible aesthetic, highlighting the wholesome journey of discovering herbs to make tea.
Apart from these, there are many indie games which also include Co-Op Games, to look forward to.
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Covering soccer is a totally different ball game in comparison to Rugby. I covered the Celtic vs Maritzburg match two days ago at the Seisa Ramabodu stadium in Rocklands near Bloemfontein. I would like to share a few thoughts on capturing this game on camera. I really covered a lot of matches at the Seisa Ramabodu stadium the last couple of years and must say that not for one moment I felt unsafe when busy shooting in the stadium or walking to my car etc. The people are very friendly and always helpful.
Okay – the main difference between Rugby and Soccer is that when shooting rugby one normally follows the ball and when shooting soccer a lot of time one is seeking for the guy who will probably receive the ball from a pass or the goalie from a shoot.
Further, I got different favourite spots"" to sit at than those of rugby. I figured this out while I was covering the Soccer World Cup in 2010 in South Africa. During a World Cup one must position yourself at the seat that is allocated to you which means during 15 Matches during the World Cup I was sitting at 15 different spots.
The reason for these spots is that I feel more comfortable when the open side is to my right and it feel that I can move more freely than when the open side is to my left because your left hand is on the monopod and one's right hand on the shutter. Well ….yes… Maybe it doesn't make sense but go and try it.
Spot 1 and 3 are exactly the same just on the opposite side of the field. Spot Number 2 is on the sideline and is a great place to shoot some action in the goal area from.
The reason why I didn't marked the right side of the field is because that part where the players(Bench) are sitting is normally out bounds for the photographers.
The settings that I used were the same that I used shooting rugby mentioned in the previous post of mine.
Wilson Olomu from Maritzburg United F.C. looking for his shooters.
With soccer I also am using two cameras, one with the 400mm F2.8 and 1.4 converter fitted to it and the other one with the Nikon 300mm F2.8 fitted to it. The 300mm works well in the goal area(green area) specially from corner kicks.
I will cover most of the action in midfield with the Nikon D3 and 400mm. When the game is getting closer I will start looking for the shooters near the goal area who will receive the ball from the midfielders or the wings. If there is time I will switch to the 300 mm lens but normally there isn't so I will stick with the 400mm and wait for a corner kick before switching to the 300mm lens.


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Los serrasalminos (Serrasalminae) son una subfamilia de peces de la familia Serrasalmidae. La mayoría de las especies de esta subfamilia son conocidas como pirañas y viven en ríos de aguas templado-cálidas y cálidas de América, con mayor abundancia en la Amazonia.

Géneros
Se indican los 6 géneros de la subfamilia, con sus nombres comunes:
 Catoprion Müller & Troschel, 1844 caribe
 Metynnis Cope, 1878 moneda, dólar
 Pygocentrus Müller & Troschel 1844 piraña
 Prosomyleus Géry 1972
 Pygopristis Müller & Troschel 1844
 Serrasalmus Lacepède 1803 (incluye Pristobrycon Eigenmann 1915) piraña

Taxonomía
Anteriormente estos peces eran clasificados en la familia Characidae. Ahora, Serrasalminae fue limitada en su contenido genérico, elevándose todo el conjunto en una familia propia: Serrasalmidae.

Pese a las dificultades de clasificación, este grupo está bien definido si se lo compara con otros grupos de peces neotropicales, y hay amplio acuerdo en cuáles son los géneros y especies que deben ser incluidos.

Distribución
Estos peces provienen de América del Sur. Hay especies distribuidas en todos los sistemas fluviales importantes que drenan hacia el océano Atlántico desde los 10° de latitud N latitud hasta los 35° de latitud S.

Referencias

Enlaces externos

redpajama_set_name: RedPajamaWikipedia


text:
NGC 117 ist eine Linsenförmige Galaxie vom Hubble-Typ S0/a im Sternbild Walfisch südlich der Ekliptik. Sie ist schätzungsweise 244 Millionen Lichtjahre von der Milchstraße entfernt und hat einen Durchmesser von etwa 50.000 Lichtjahren.

Das Objekt wurde am 13. September 1863 von dem deutschen Astronomen Albert Marth entdeckt.

Weblinks

 SIMBAD Astronomical Database
 CDS Portal

Einzelnachweise


Many people in Lynn Ranch Thousand Oaks California opt to employ an accident legal representative after they've been associated with an auto accident that results in personal injury and monetary losses.
Technically, you can file an accident claim versus an insurer by yourself. Some people select this path when they've suffered just moderate injuries and have the time to research the legal claims process themselves. Avoiding an attorney will save you some loan in legal charges.
An accident attorney– specifically a personal injury attorney– can help you go up versus huge car insurance business and their group of lawyers. Your attorney currently understands the accident laws and procedural rules and can successfully manage all the legwork for you. He or she will act as your supporter throughout the whole case.
Expense of medical costs (and any other restorative procedures) you have actually incurred.
Typically speaking, a long-term injury is one that lasts for around a year or longer, while a long-term injury is one that disables you for life. These types of personal injuries seriously impact your ability to end up being and remain used– not to mention the quality of your life.
Showing long-lasting and completely disabling injuries can be difficult organisation, and your accident lawyer most likely will talk to each doctor you have actually seen. He or she even may request the presence of your medical professionals during any legal proceedings.
When an insurance provider challenges its policyholder's liability for the car crash, the company is basically stating that the insurance policy holder is not at fault (or is at least declaring you do not have enough proof of fault) and, therefore, the insurance company is not responsible for paying for your damages.
An accident lawyer in Lynn Ranch Thousand Oaks CA will help you provide this evidence and show that the other party was undoubtedly at fault.
Refusal to pay (which can but does not necessarily come from a challenged liability) or refusal to pay a fair amount is when an insurance company outright won't make a fair settlement deal– or any offer at all.
Because of possible situations such as statutes of limitations (which can vary by state), it is necessary to hire an accident lawyer and get the claims process going as rapidly as possible; however, you do not want to employ the first lawyer for whom you see a signboard on the highway.
Think about these ideas as you search for the right accident legal representative.
Just as there are several medical professionals who concentrate on various areas of medicine, there is a large range of attorneys from which to pick.
As you choose your accident lawyer, make certain she or he concentrates on accident mishaps.
In some cases, assessing your convenience level can avoid you from working with a personal injury attorney who isn't really well fit for your case; other times, it might convince you it's time to change course with a new lawyer.
Just keep in mind, you suffered accident near Lynn Ranch Thousand Oaks and monetary loss due to a car crash you think somebody else triggered. Use these pointers– and trust your gut– as you look for the ideal accident legal representative.


On behalf of D.C. Schroth Organ Builders, we wish you a most blessed and happy Easter! The Schroth family has another reason to celebrate. Last evening, we brought our beautiful little daughter, Heidi Elizabeth, into the world. She was a healthy 9lbs. 8 oz and 22 inches. Mama and baby are doing wonderfully well.


You meet a guy that you actually like. Finally, the universe is throwing you a bone. He asks you on a date. You cannot hide the excitement and it almost seems like your heart is going to burst out of your chest.
You go out with him and there are sparks flying all over the place. The fireworks between the two of you are so intense and bright that you start imagining your whole life beside them.
But then, after a certain period of dating and slowly falling love with him, he notices that you are getting too attached and he just vanishes. Completely disappears in thin air. Suddenly, you are left all alone, wondering why he would do that to you when he said that he loved you.
You are hoping that he will come back, but as days pass by, that hope grows smaller and smaller. Until you finally realize that you've fallen in love with a heartless and immature person who manipulated you and left you the second you revealed your vulnerable side.
This might sound a bit over the top, but the reality out there is not really different than this story. The game of dating is sometimes crueler than you think. You fall in love for the first time, you let your guard down and BAM! Your 'beloved' strikes you down.
It hurts I know. And it is pretty normal to feel frustrated and angry for days. It's pretty normal to want to find them, punch them in the face and then beg them to come back to you. It's all a part of the healing process.
However, wanting and doing that are two completely different things. Because, if you think that begging him to get back to you means fighting for your relationship, you are terribly wrong. A person who leaves you does not love you. Therefore, bombarding his voice mail and his messenger with 50 messages won't change that fact.
So, here's what. Why don't you just take the hint and get over it?
I know that it's easier to say it than to actually do it, but I mean, come on… You cannot possibly tell me that you are willing to fight for this person after he broke your heart and cold-bloodedly ghosted you. That is madness. Or shall I say, masochism?
Instead of being that sad, pathetic and miserable girl who begs for love and attention, be the girl who will let go of him the minute she senses that he's no longer interested.
When I think about how much time and energy I've wasted on people who were not worthy enough I honestly want to cry. All of that precious time could have been spent doing something more productive, something more rewarding. But, oh well. It is what it is. After all, mistakes are done to help us grow and evolve as people.
That is exactly why I am saying this to you.
I may have suffered the consequences of following my dumb girl logic and my pure, naïve, loving heart, but you don't have to. There's nothing worse than regretting your actions and longing for the years that you've wasted in vain.
So, please let's just stop holding on to people who do not value us. Let's stop giving third chances to people who didn't even deserve the second. Let's stop investing our energy in relationships that are bad for us.
Life is to short to spend it fighting for someone who does not care about you. If the love does not challenge you, inspires you to grow, fills you with passion and sparks a fire inside your heart, then it's not worth it. Trust me.


text:
Q: Auto testing for Microsoft Bot Framework I'm working now on my first bot with Microsoft Bot Framework, with ASP.NET.
After manually testing with the bot emulator, I'm looking for the best method to create automatic testing for the bot.
Considering two problems:

*

*What is the best tool to automate such tests?

*What is the best method to test a dialog that can return different answers to the same input?

A: One alternative is doing functional tests using DirectLine. The caveat is that the bot needs to be hosted but it's powerfull. Check out the AzureBot tests project to see how this works.
Another alternative, is doing what the BotFramework team is doing for some of their unit tests.
If you are using Dialogs, you can take a look to the EchoBot unit tests as they are simple to follow.
If you are using Chain, then take a look to how their are using the AssertScriptAsync method.

*

*https://github.com/Microsoft/BotBuilder/blob/master/CSharp/Tests/Microsoft.Bot.Builder.Tests/ChainTests.cs#L360

*https://github.com/Microsoft/BotBuilder/blob/master/CSharp/Tests/Microsoft.Bot.Builder.Tests/ChainTests.cs#L538
If you are looking for a way to mock up Luis Service, see this.

A: You may want to consider Selenium. Selenium is web browser automation software allowing you to write tests that programmatically read and write to the DOM of a web page. With a Selenium script you can:

*

*login on any channel that provides a web client (and most of them do: WebChat, Telegram, Skype, Facebook, for example)

*start a conversation with your bot

*perform operations such as post a message to the chat and wait for a reply

*test whether the reply is what you expected.

A: For automated testing of bots in Node.js, using ConsoleConnector in the same way as the tests in BotBuilder on GitHub works well, e.g. take a look at https://github.com/Microsoft/BotBuilder/blob/master/Node/core/tests/localization.js:
var assert = require('assert');
var builder = require('../');

describe('localization', function() {
this.timeout(5000);
it('should return localized prompt when found', function (done) {
    var connector = new builder.ConsoleConnector();
    var bot = new builder.UniversalBot(connector);
    bot.dialog('/', function (session, args) {
        session.send('id1');
    });
    bot.on('send', function (message) {
        assert(message.text === 'index-en1');
        done();
    });
    connector.processMessage('test');
});

...etc...

redpajama_set_name: RedPajamaStackExchange


There are dozens of horrible stories about traveling for vacation. However, the bottom line is, the nightmare would probably not have happened with good planning. This shouldn't be a problem. This article will give you tips so you have an enjoyable vacation.
When traveling abroad, keep a note of all important information. Record the address, website, and telephone number of the embassy or consulate in your country of destination. This will let you contact help if you need it. This will help with the troubles that you get into.
Once you know where you are going, put in some time to learn your destination. Find a good map of your destination, and take some time to learn about the geography and the main attractions. If you have a basic idea of where you are going and what you are doing, you will find that your trip goes more smoothly.
Some Northern Cyprus Travel destinations require specific vaccinations before you can North Cyprus Travel there. Make sure you've researched the destination thoroughly and have updated your needed vaccinations. This can be a lifesaver when leaving or entering a country, and immunizations can even be an issue when traveling from one city to another within one country. Without that paperwork, officials have no means of verifying that you've actually been vaccinated, and that can cause delays or even a quarantine.
If it's too hard to leave your furry friend at home, bring her along. Allowing patrons to bring their pets is becoming quite popular with vacation spots and many offer special deals and discounts for pet parents. Most involve activities as well as pampering services for your beloved pet that may leave you jealous that they are having a better time than you. Don't fear taking your furry friend along, as long as you make sure you can before you do.
Be wise about food allergies when visiting a foreign country to avoid dangerous liaisons. If you do have an allergy, you will need to have a good handle on the language of the country you are eating in. By doing this, you can tell any wait staff or food handlers that you must avoid these certain foods or, even in a worst case scenario, you need to be able to tell medical professionals what is wrong.
Bring along a door stopper to provide an extra measure of safety when you stay in a hotel. If you are travelling in a country less developed, it is important that the hotel have added security, especially at night. If your door doesn't contain a chain or deadbolt, place a doorstop under the door.
Bring along things to keep your toddler busy. Bring along anything your child loves to play with. You might want to purchase a new item for this trip to bring some novelty to the adventure and ensure more time is occupied by the toddler.
Whenever you travel, only bring what you need and travel light. The more you pack, the more you may have to carry, pay excessive luggage fees for and then keep up with. Limit how many shoes you take as they can take up a lot of room and are the heaviest things you will be taking.
Keep everything in one place. Avoid wasting too much time looking through your home for Northern Cyprus Travel accessories. Get a bin and keep all of your North Cyprus Travel items in one place. An under-bed container works well to keep things hidden, but ready for you to quickly jet off on your next adventure.
When making a hotel reservation, try asking about dates for any possible renovations if you can. Nothing is more annoying than to be woken early in the morning by construction equipment, especially when you are on vacation. The hotel staff is powerless about such noise, so your best bet is just avoiding potential construction dates altogether.
Pack a few cooking sheets if you have children. They can be used to make flat surfaces for playing cards or a surface for coloring books. If you have little ones, you can bring magnetic letters and numbers for educational fun.
Get yourself a National Parks Pass if you think you will be visiting often. Each pass costs $50. They are good all year and can be used at any national park.
If you tend to forget things in your hotel room when you are traveling, try writing down reminders to yourself on the mirror with a dry erase marker. This prevents you from losing a piece of paper, and the information will be readily available. This is a great approach, and the markers easily wipe off.
Your vacation can immediately start off on the wrong foot if you haven't planned adequately. Look at online reviews from those who've already traveled to your destination. You can find others who have taken the same vacation and their tips can be helpful.
Make sure your passport hasn't expired. Most countries have passport regulations with which you must comply. You are usually not allowed to enter a country if your passport expires soon. These range from 3 to 6 months, or could even reach 8 months to a year.
Take an early flight. There is less of a chance that it will be delayed. Usually when flights are delayed it's because they are waiting for it to arrive at the airport, but if you take the first flight out, chances are the plane is already there. The very first morning flight should not have many reasons to delay.
It is very important that you remember to bring along your vital medications. When someone is packing for a trip it is easy to forget important items like medications. If you do forget, you might find it hard to get your medicine.
When using traveler's checks, be sure to cash them prior to eating out or shopping. Although traveler's checks are accepted in most places, they're hard to deal with. You may get shorted by using them, so use local currency when spending.
If you are going on a road trip, bring your favorite music to listen to while you ride. After a while, the radio will keep turning to static as it goes in and out of different broadcast areas; your own music allows you to have something to listen to the entire trip.
People are not properly prepared for their vacations, that is why these things happen. You now have the advice needed to take the worry from your vacation and find the relaxation that you deserve.


text:
Stem Cells - Overview
About Stem Cell Therapy
Stem Cell Secretome (SCS)
Bone Marrow Concentrate (BMC)
Mesenchymal Stem Cells (MSCs)
Anti-Aging and Rejuvenation
Hair Loss Stem Cell Transplantation
Infusion Therapy Overview
Infusion Therapy – Anti-Aging
Infusion Therapy – Immune Boost
Infusion Therapy – Wellbeing Program
Infusion Therapy – Athlete's Program
Infusion Therapy – Neurodegenerative Diseases
Infusion Therapy – Arthritis
Overview - Diseases Treated
Rheumatoid Arthritis (RA)
Parkinson´s Disease (PD)
Orthopaedics and Sport Injuries
Knee Injuries and Degeneration
Treatment of urinary incontinence
Diagnostic Work-Up
About ANOVA IRM
Our Laboratory
Research News (Blog)
The Power of Exosomes
Alternatives for back surgery
Stem Cell Treatment Improves Degenerative Disc Disease and Chronic Back Pain
Does stem cell therapy for knees work
Can stem cells help with orthopedic issues
How much does stem cell therapy cost
Multiple Sclerosis: How Stem Cells Could Help
Recovering from a Knee Injury
Osteoarthritis Risk Factors
Combined Treatment for Spinal Cord Injury: Stem Cell Therapy and HAL
Stem Cell Therapy for Enhancement of Saliva Production
Infusion Therapy as a Treatment Addition
Rehabilitation and Physiotherapy
Stem Cell Secretome as an Emerging Treatment for Parkinson's Disease
Platelet-Rich Plasma for Orthopedic Treatments
A New Generation of Stem Cell Therapy Launches To The Public
The negative effect of senescent cells and targeted treatments for osteoarthritis and aging
Mesenchymal Stem Cells for the Regeneration of Damaged Brain and Spine
Does stem cell therapy for amyotrophic lateral sclerosis work?
Alternative Therapies for Parkinson
Rejuvenation Therapy – An Overview of Anti-Aging Stem Cell Therapies
Stem Cells and Erectile Dysfunction
A success story for a patient with ED
Alternatives to knee surgery
Are stem cell therapies a treatment alternative for ALS
Are stem cell therapies a treatment alternative for MS
Spinal Cord Injury - Can stem cell therapies be applied?
Are stem cell therapies a treatment alternative for ED
Clinical Perspectives
Clinical Perspectives - Overview
Stem Cells for Neurodegenerative Diseases
Stem Cells for Osteoarthritis
Impressum Legal Notice EN
ALS Stem Cell-based Exosome Treatment
Stem Cell Therapy for Amyotrophic Lateral Sclerosis
at ANOVA IRM in Offenbach, Germany
Amyotrophic Lateral Sclerosis (ALS) is caused by the progressive death of cerebral (upper) and spinal (lower) motor neurons. It is a complex disease which involves the activation of several cellular pathways in both neurons and glial cells. This results in a severe motor dysfunction muscles become atrophic due to the lack of nerve stimulation. Often, the origin of the disease is unknown. ALS is not a typical autoimmune disorder, since autoimmune and inflammatory abnormalities are not the cause of the disease, even though they influence its progression.
Stem Cell-based therapies may be the answer. A study by Mazzini et al. demonstrated that the procedure of ex vivo expansion of autologous Mesenchymal Stem Cells (MSCs) and transplantation into the spinal cord of humans was safe and well tolerated by ALS patients. A more recent study, by the same group, however, confirmed that MSC transplantation into the spinal cord of ALS patients is not only safe, but might also serve as a treatment option for future cell-based clinical trials for the treatment of ALS.
Many current pre-clinical studies suggest that stem cell transplantation has the best effect when aimed towards protecting, rather than replacing or repairing the motor neurons of ALS patients. Our experience shows that Stem Cell Secretome is a promising, novel strategy that appears to be more effective and safer than the cells themselves. Stem Cell Secretome is the essence of stem cells, and can facilitate neuro-protection and recovery of neuro-motorial function. ANOVA offers this experimental and novel stem cell-based therapy patients with ALS. For more information, please feel free to contact us.
Diagnostics - Treatment - Medication - Stem Cell Therapies
On this page we inform you about ALS covering an overview on important aspects of causes, treatment options, precision diagnostics as well as our stem cell-based therapies that we offer in Offenbach (near Frankfurt am Main airport), Germany.
Jump directly to the following topics:
Conventional therapies
ANOVA therapies for ALS
Expectations and limits
Our treatment options
Workflow of the treatment process
MSC secretome - exosome - therapy
ANOVA IRM - Germany
Conventional ALS Therapies vs. Stem Cell Therapy
The therapeutic strategy used for treating ALS is aimed at protecting neurons from degeneration, and to stimulate cell regeneration. However, currently there is no drug treatment that can restore neural cells.
Conventional Therapies are e.g.:
drugs to relieve painful muscle cramps
drugs inhibits excessive salivation production
heat or whirlpool therapy to reduce muscle cramping
Physiotherapy to retain as much muscle strength as possible
Physiotherapy to reduce muscle stiffness and cramps
Nutritional supplementation and healthy diets
Recently, the US FDA approved Rilutek®. It is the first drug that has prolonged the survival of ALS patients. It failed, however, to stimulate regeneration or recovery from established damage.
Effects of ALS in a MRI image
ANOVA IRM Germany
Stem cell research has allowed ANOVA, a German Stem Cell Clinic in the heart of Europe near Frankfurt/Main airport, to offer a novel treatment with a new therapeutical approach: The ANOVA Stem Cell Secretome is a cell free and promising treatment option for ALS.
Call us today, whether you wish to apply for a treatment, or simply receive more information.
Please use our contact form
Stem Cell Treatments for Early ALS at
ANOVA Institute for Regenerative Medicine - Offenbach, Germany
Secretome/Exosomes of MSC
Potency Hypothesis of Stem Cell Therapies
Stem cells possess the potential to communicate with the immune cells that elicit inflammation and by natural, so far not understood mechanisms may inhibit this immune-over-reaction. Furthermore, stem cells have the ability to stimulate regeneration of tissue thereby counteracting the loss of function.
MSEC - Mesenchymal Stem Cell Secretome - Exosomes - Autologous
As ALS is a chronic, so far not curable disease, we on-goingly treat patients with early to mid-stage ALS with MSEC (secretome, exosomes, EVs) of mesenchymal stem cells (MSC, AD-MSC, adipose-derived, fat-derived stem cells) which we harvest from the patients belly in a mini-liposuction (very brief and limited liposuction) under slight sedation. Worldwide, ANOVA is the first stem cell clinic to acquire legal permission form the responsible governmental authorities and therefore, offers high quality, safe and legally-controlled autologous (own) exosome-containing secretome.
The main advantage of MSEC is that in contrast to live stem cells which would loose their therapeutic potency, can be frozen without loss of exosomes. This enables us to produce 10-20 injection doses from one liposuction which can then be administered over a longer treatment period. This is especially advantageous for repeated stimulation of cell survival and regeneration in ALS. What a Secretome/Exosome is and how they compare is explained on our overview page.
Please note that this treatment is not a cure but as any stem cell treatment an experimental, potentially disease-modifying therapy. It requires regular and repeated travelling to Offenbach, Germany.
Our stem cell treatments are experimental, but we only treat patients for whom we believe the risk/benefit ratio indicates treatment based on the state of the art, i.e., medical, scientific evidence.
Please understand that we therefore do not treat patients for whom the following points apply:
Active cancer in the last two years
Not yet of legal age
Existing pregnancy or lactation period
Unable to breathe on own, ventilator
Difficulty breathing in supine position
Dysphagia (extreme difficulty swallowing)
Psychiatric disorder
Infectious disease (hepatitis A, B, C, HIV, syphilis, or other)
Therapy Workflow for Early to mid-Stage ALS
The precise workflow is described in detail on the stem cell- specific pages of BMC, Secretome/Exosomes and PRP (as combination therapy).
All therapies are divided into phases such as evaluation of the medical history (we analyze your current therapies and medical records), initial counseling and evaluation of potential, patient-individual benefit of a stem cell therapy (indication statement), preliminary examinations, diagnostics, consultation on all therapy options, preparation of an individual treatment plan including cost estimate, harvesting of tissue, production of the stem cell product, quality control of the product and application.
Unfortunately, we only treat patients in an early to mid-stage of ALS. Patients have to breathe unassitedly and have to be fit for the sedation and brief intervention necessary to harvest fat tissue. And according to the risk-benefit ratio, we cannot treat children or pregnant women. In addition, other factors can also be exclusion criteria.
How Long Does a Stem Cell Therapy Take?
The initial analyses and counseling can be done without you having to travel to Offenbach (near Frankfurt/Main, Germany). This period can be 2 weeks up to months depending on the availability of patients slots. If you live further away, we will conduct the initial discussions by telephone or video conference. For the actual treatment, you will travel to Offenbach.
Secretome/Exosome-therapy:
Preparation and harvest of the fat (mini-liposuction) need once 2 days (consecutive days) in Offenbach, followed by enrichment of the mesenchymal stem cells (Secretome/Exosome) and quality control. Approximately 4 weeks after the isolation, the therapy begins according to the therapy plan determined with you. You will then come to Offenbach am Main (Germany) in regular intervals for the application. Depending on where you live and your traveling capacity and restrictions the treatment pattern is adjusted to your needs and abilities. The shelf life of the secretome (exosomes) is 2 years. As ALS is not curable with any treatment, we recommend a double-lipo which produces 20 doses for a continuous treatment over 2 years. Thereafter, a new liposuction has to be performed.
How much Does Stem Cell Treatment Cost?
Our treatments are always tailored to your specific situation, disease, stage and other factors. The therapies differ in the product used (BMC, secretome, PRP or hyaluronic acid), the frequency of treatment as well as the further examinations and your sedation and anesthesia wishes. A treatment for ALS will cost well above ten thousand euros. You will receive a cost estimate for all treatments in advance so that you can accurately estimate what a treatment would cost in your individual case.
Does my Health Insurance Cover the Therapy Costs?
Unfortunately, at the moment it is assumed that health insurance companies do not cover the costs of experimental therapies (BMC, secretome, PRP, micro-fracture technique), i.e. you will have to bear the costs entirely yourself.
Understanding ALS on a Cellular Level
This figure shows the complexity of ALS, which involves many different pathways in motor neurons and neighboring glia. Microglia (bottom part) activate an inflammatory cascade via MCP-1 secretion. Astrocytes (purple cells) contribute to the injury of motor neurons through various mechanisms, including release of inflammatory mediators such as NO and PGE2 (left), reduced expression and activity of the glutamate transporter (right), reduced lactate release (top left) and activation of pro-NGF–p75 receptor signaling (left). Motor neurons also undergo abnormal RNA processing which, together with overproduction of reactive oxygen species (ROS), contribute to protein mis-folding (center). Mis-folded proteins can form aggregates, leading to cellular stress and ultimately activate autophagy and apoptotic pathways. Two major components of motor neuron injury are mitochondrial impairment and dysregulation of calcium handling (top middle) which also stimulate the apoptotic cascade. Impaired axonal transport (left bottom) may contribute to an energy deficit, disturbing normal functionality (distal axonopathy). Abbreviations: EAAT2, excitatory amino acid transporter 2; ER, endoplasmic reticulum; IL, interleukin; MCP-1, monocyte chemo-attractant protein 1; NGF, nerve growth factor; NO, nitric oxide; PGE2, prostaglandin E2.
Quelle: By Jmarchn-Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=95036158
Stem Cell Secretome Therapy for ALS
Several clinical trials with stem cells for ALS are ongoing. As usual during studies, new insights emerge. The ANOVA Stem Cell Secretome is the product of the latest insights to what actually causes the stem cell therapies to be effective. Stem Cell Secretome for ALS employs mesenchymal stem cells (MSC) secretome for a variety of reasons.
As explained in detail in our Information for Professionals section, MSCs can secrete many trophic and neuro-protective factors. Additionally, among the micro vesicles secreted from the MSC, are the very important exosomes transporting microRNAs (miR-29a, miR-9, miR-124, miR-145). It is known that the exposure of neurons and astrocytes with MSC secreted exosomes leads to an increase of miR-133b which was shown to promote functional neurological recovery.
The ANOVA Stem Cell Secretome harnesses these and many other factors in a high concentration.
It is important to note that novel therapies such as stem cell-based therapies have not undergone the full clinical evaluation yet. Therefore, the attending physician must assess the risks and benefits associated with stem cell therapy for each patient individually. If the benefits outweigh the potential risks, the doctor may suggest experimental therapies to the patient.
References and Literature - Stem Cell-based Therapies for
Amythrophic Aateral Sclerosis-ALS
Wijesekera, Lokesh C., and P. Nigel Leigh. "Amyotrophic lateral sclerosis." Orphanet journal of rare diseases 4.1 (2009): 3.
Ferraiuolo, Laura, et al. "Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis." Nature Reviews Neurology 7.11 (2011): 616-630.
Mazzini, Letizia, et al. "Stem cell therapy in amyotrophic lateral sclerosis: a methodological approach in humans." Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 4.3 (2003): 158-161.
Mazzini, L., et al. "Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: A Phase I clinical trial." Experimental neurology 223.1 (2010): 229-237.
Papadeas, Sophia T., and Nicholas J. Maragakis. "Advances in stem cell research for Amyotrophic Lateral Sclerosis." Current opinion in Biotechnology 20.5 (2009): 545-551.
Janson, C. G., et al. "Human intrathecal transplantation of peripheral blood stem cells in amyotrophic lateral sclerosis." Journal of hematotherapy & stem cell research 10.6 (2001): 913-915.
Thomsen, Gretchen M., et al. "The past, present and future of stem cell clinical trials for ALS." Experimental neurology 262 (2014): 127-137
Staff, Nathan P., et al. "Safety of intrathecal autologous adipose-derived mesenchymal stromal cells in patients with ALS." Neurology 87.21 (2016): 2230-2234.
Oh, Ki-Wook, et al. "Phase I Trial of Repeated Intrathecal Autologous Bone Marrow Derived Mesenchymal Stromal Cells in Amyotrophic Lateral Sclerosis." Stem cells translational medicine 4.6 (2015): 590-597.
Petrou, Panayiota, et al. "Safety and clinical effects of mesenchymal stem cells secreting neurotrophic factor transplantation in patients with amyotrophic lateral sclerosis: results of phase 1/2 and 2a clinical trials." JAMA neurology 73.3 (2016): 337-344.
Farinazzo, Alessia, et al. "Murine adipose-derived mesenchymal stromal cell vesicles: in vitro clues for neuroprotective and neuroregenerative approaches." Cytotherapy 17.5 (2015): 571-578.
Bonafede, Roberta, et al. "Exosome derived from murine adipose-derived stromal cells: Neuroprotective effect on in vitro model of amyotrophic lateral sclerosis." Experimental cell research 340.1 (2016): 150-158.
Boruczkowski, D., et al. "Mesenchymal Stem Cells As A Therapeutic Option For Patients With ALS." Gen Med (Los Angel) 4.235 (2016): 2.
Literature and References HAL training for ALS treatment
Nakajima T, Sankai Y, Takata S, Kobayashi Y, Ando Y, Nakagawa M, Saito T, Saito K, Ishida C, Tamaoka A, Saotome T, Ikai T, Endo H, Ishii K, Morita M, Maeno T, Komai K, Ikeda T, Ishikawa Y, Maeshima S, Aoki M, Ito M, Mima T, Miura T, Matsuda J, Kawaguchi Y, Hayashi T, Shingu M, Kawamoto H. Orphanet J Rare Dis. 2021 Jul 7;16(1):304. PMID: 34233722 Free PMC article. Clinical Trial. https://doi/10.1186/s13023-021-01928-9. RESULTS: We conducted an open-label, randomised, controlled crossover trial to test HAL at nine hospitals between March 6, 2013 and August 8, 2014. ...Cybernic treatment with HAL resulted in a 10.066% significantly improved distance in 2MWT (95% confidence interval, …
Morioka H, Hirayama T, Sugisawa T, Murata K, Shibukawa M, Ebina J, Sawada M, Hanashiro S, Nagasawa J, Yanagihashi M, Uchi M, Kawabe K, Washizawa N, Ebihara S, Nakajima T, Kano O. J Clin Neurosci. 2022 Mar 10;99:158-163. Online ahead of print. PMID: 35279589 Free article. https://doi.org/10.1016/j.jocn.2022.02.032. We used HAL for patients with amyotrophic lateral sclerosis (ALS) to determine whether HAL training had an effect on their gait ability. ...The 10-meter walk test showed significantly improved cadence, although gait speed, step length on the 10-m walk, or ADL …
Sczesny-Kaiser M, Kowalewski R, Schildhauer TA, Aach M, Jansen O, Grasmücke D, Güttsches AK, Vorgerd M, Tegenthoff M. Front Neurosci. 2017 Aug 8;11:449. eCollection 2017. PMID: 28848377 Free PMC article. https://doi.org/10.3389/fnins.2017.00449. Recent studies have shown that the voluntary-driven exoskeleton HAL (hybrid assistive limb) can improve walking functions in spinal cord injury and stroke. The aim of this study was to assess safety and effects on walking function of HAL supported treadmill therapy …
Further References for MSC, BMC, Stemcell Secretome and EVs
Further References about PRP
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I just got back from Tom's and we had a great time there talkin' about rods and fishin stuff. I got 8 rods back, 6 of them mine including a brand new MHX-HM spinning rod. This is their Ferrari of blanks, and they truely are super strong and lighter than most but not as light as IMX or GLX or the North Fork Composites blanks sold to other brands such as Kistler.
*Reel Seat is American Tackle Aero with the comfort grip finish and is top of the line in weight and comfort.
If you want it made, and made correctly, contact Tom at tom@tomscustomrods.com.
If you don't know jack about rod building and blanks and parts, it's NO problem. Tom is a matchmaker for blanks and your needs. He's built hundreds and hundreds of rods using every possible blank and componet available.
I know I love mine.
Thanks Bob.....Tom has the other one there also, almost done. Loomis blank 6'6" with the same guides and reel seat, except this one has EVA grips.
Man, that rod look familiar also. I am sure you will love it.
Thanks Kris. It's now paired with an Okuma RTX30S, with 8lb CXX hi-vis. This is a great shakeyhead blank with a ton of power. Also great for sliding weighted sencos through grass.
How close to the 6'8"MXF St Croix Avid X rod is the action?
The MHX High Mod is MUCH stiffer and more tip heavy. This is the more MH action one. It's no joke, i could put 30lb braid and a 4" sassy shad on this rod with a larger 4000 size reel, and i could go to town on the stripers, which i will.
This rod is going to be perfect for heavier 1/2oz to 3/4oz shakeyheads, and smaller 1/4oz Bitsy Bug jigs.
For sliding sencos through grass, this thing is perfect...its got the backbone for sure. Its a little on the stiff side for ned rigs, or weightless smaller sencos. It would be great for fluke skipping and fishing also.
For someone who would rather use a spining rod for nearly everything, this right here is THE blank.


How can you refuse when a friend asks you to meet them in Venice? You simply cannot and so I find myself heading there for the weekend, rather spontaneously! We decided I think on Sunday evening! My friend, whom I lived with whilst at University, is living in Dubai, but has popped over to Europe for the week and as our meet ups are now spread so far apart from one another, they are even more special! So I am super excited!
This will be my second trip to the city this year, as I went to meet another friend from University there in March, when we ended up going for a Venetian Rowing lesson which you can read about here and I attended a talk by Art Historian and presenter of the BBC's Italy Unpacked Andrew Graham-Dixon. The talk you can also read about here.
I am not sure what we have planned for this weekend, but I am sure we will end up having an adventure or two! The first, shall be finding one another…I don't think I have ever visited Venice, without getting a little lost!
I am looking forward to my train journey as I can read some more of Elena Ferrante's My Brilliant Friend, which is the first book I am reading for my Read Around the World feature! More to come on that soon, but you can read my first post here and I am still looking for suggestions of other books, from each country around the world! So let me know if you have any!
For now, I must pack, as I am prone to leaving things to the last minute! Only thing is, I am at a loss as to what to take! This week has been a disaster weather wise, Wednesday was 13 degrees, stormy and rainy (I even wore wellies!), Thursday and Friday 23 degrees and sunny! It makes my head spin all this weather changing…but the forecast says it should be nice, so fingers crossed!
Whilst I was home for the summer, my parents and I (as well as the dog!) decided to spend a few days in Suffolk. We stayed at The Westleton Crown on the Suffolk coast between Southwold and Aldeburgh. The Crown is a charming hotel, restaurant and traditional pub, serving delicious food, with a great atmosphere and of course dog-friendly – Robbie loved sitting in the lounge after dinner! All the rooms were named after birds, rather than having numbers, which was a rather charming touch! I was in the Wren room and my parents in the Nuthatch.
We had a very relaxed few days visiting Snape Maltings, Southwold Pier, Dunwich, Dunwich Heath and Woodbridge. The countryside in Suffolk is beautiful, especially Dunwich Heath where we went for a really lovely long walk (getting just slightly lost at one point), before heading back to the National Trust tea rooms for tea and scones! Perfect and how very English!
It was a rather rainy day when we visited Southwold Pier, but I love how this image looked when I gave it this filter! Slightly mysterious!
The Pier has an 'Under The Pier Show' with hand-built machines, all a little quirky and out there! I had a go on the 'Crankenstien', which you have to wind up and watch as Crankenstien becomes more and more angry! It made me jump when he suddenly screams at you!
British street artist Pure Evil, created this piece of art to commemorate George Orwell and the time he spent in Southwold. Orwell wrote 'A Clergyman's Daughter' whilst in Southwold. The artwork will remain a permanent feature of the pier.
Giant (and surprisingly comfy!) deckchairs at Dunwich Heath!
In the village of Westleton, where we stayed, there was a really interesting and quirky second hand book shop! My Dad found three history books, and when you wanted to pay, there was an old oil can and a wooden stick which you had to beat to get someone's attention! Very eccentric…but charismatic! They even offered us a cup of tea!
If you have never been Suffolk is a lovely place – great countryside, friendly people and it feels very traditional, very British! If you have been, where did you enjoy visiting? What did you see and do?
I have lots of posts planned for the next few weeks, including a review on The Curious Incident of the Dog in the Night-Time play, photo posts from my break in Suffolk and weekend in London and how living in Italy has changed me, as well as how I am still British through and through.
I hope you have all had a lovely weekend!


Asiago is a vampire, and like all vampires, he avoids the sun, wood, and garlic. When his friends invite him to the beach, he is excited to go. But after getting a sunburn, a wooden splinter in his foot, and a stomachache from eating clams with garlic sauce, Asiago can't wait to get home. Luckily, his friends come up with a clever solution that makes it possible for Asiago to enjoy the beach.
Author/Illustrator Adam McHeffey used color pencils to create a vampire that is so appealing, children ages 4-7 will want to meet him again and again. Buy this book today for 99 cents.


For a while now, there has been expectation of First REIT doing some acquisitions and in the process would have the need to raise funds. First REIT's management announced on 9 Nov 10 a 5 for 4 rights issue at 50c per unit.
The Mochtar Riady Comprehensive Cancer Centre ("MRCCC") is being acquired from Wincatch Limited, an unrelated third party, for S$170.5 million, and Siloam Hospitals Lippo Cikarang ("SHLC") is being acquired from the sponsor of First REIT, PT Lippo Karawaci Tbk, for S$35.0 million.Read announcement here.
Including fees and expenses, MRCCC would cost S$174.6m while SHLC would cost S$35.9m. Total acquisition cost: S$210.5m. The rights issue would raise gross proceeds of $178.2m. First REIT would take a 4 year term loan facility of S$50m from OCBC to make up the balance.
The rights issue would more than double the number of units in issue to 624,104,000 units. So, although the NAV increases to S$474,200,000, post rights, NAV per unit would decline from 98c to 76c. Gearing level is largely unchanged and remains low as much of the funds required for the acquisitions is obtained through equity and not debt.
Of greater interest to unitholders is the distributable income which would increase 84% post acquisitions from S$20,964,000 to S$38,542,000. The annualised DPU would, however, reduce from 7.62c to 6.18c due to the larger number of units in issue. So, is this rights issue a good deal for existing unitholders? To answer this question, look to distribution yield.
The theoretical ex-rights price (TERP) is calculated to be 70c based on a CR price of 95c. At 95c, the yield, with an annualised DPU of 7.62c is 8.02%. At the TERP of 70c and an expected annualised DPU of 6.18c, XR, the yield is 8.83%. So, this acquisition is distribution yield accretive and is good for current unitholders.
Unitholders have the option to sell their nil-paid rights when trading starts if they do not wish to pay for them. Based on the exercise price of 50c and the TERP of 70c, we could see the selling of the nil-paid rights at 20c or so. This could be viewed as a return of capital.
Assuming that a unitholder has 4 lots in First REIT and is entitled 5 lots of rights. By selling the nil-paid rights at 20c per unit, he would get $1,000. This is the difference between the CR price of 95c and the TERP of 70c (i.e. 25c x 4,000). There is no capital gain per se. However, the distribution yield on his existing investment will actually improve from 8.02% to 8.83% without him having to cough up more funds. So, am I saying that we should sell the rights? Well, if we do not have enough funds to pay for the rights, this is not a bad idea.
Personally, I would pay for the rights. This is because the distribution yield would improve 10% from 8.02% to 8.83% with the acquisitions and rights issue. So, the additional funds I am putting in would enjoy a most attractive yield.
Furthermore, from the recent experience with the rights issue of AIMS AMP Capital Industrial REIT in which the TERP was 21c, the XR unit price ended higher and it is currently trading at 22.5c. So, with First REIT, we could see the XR price higher than the TERP of 70c. How much higher? Based on the assumption that units should trade closer to 8.02% yield, the CR yield at 95c, we could see First REIT's unit price going 10% higher to 77c, XR. Accepting and paying for the rights could, therefore, lead to capital gains.
Good luck to fellow unitholders.
First REIT: This one is for keeps.
Thank you AK. My thoughts exactly.
Lets see how much excess (above rounding up) that we can tikam for.
when do we need to fork out $ for the rights? is it upon lodgement of the proxy form or after the nil paid rights trading ends?
I believe we can accept and pay for the rights once trading of nil-paid rights starts on 8 Dec. It is just a guess.
The time-table did not state the last date for acceptance and payment of rights.
A query: based on ur example on a unitholder buying up 4 lots @ 95c n entitled 5 lots rights issue @ 50c, wouldn't the unitholder needs to fork out $2.5 k before he is entitled to own n able to trade the rights issue? No? Then how would he not fork out any extra money for this?
And his total investment outlay wld be 95c x 4 lots + 50c x 5 lots = $6300... correct?
Pls correct me if I'm wrong. Thanks!
If someone buys 4 lots at 95c/unit, he would fork out $3,800. He would be given 5 lots of nil-paid rights. These are free which he could sell in the market when nil-paid rights start trading on 8 Dec, if he so chooses.
If he chooses to keep these rights, he would have to pay 50c/unit = $2,500. In such a case, his total investment is $6,300.
In other words, all the free rights given to the unitholder sold at the market price before the end of the rights trading period would have gone towards reducing a portion of initlal outlay, assuming unitholder doesnt take option to purchase.. Correct?
Does this concept explained works the same for all rights issue?
But alternatively, a non unitholder can also buy the mother shares during the same trading period which may be expected to fall save the mother shares may not fall below 70c, right?
Yes, selling the nil-paid rights is something like a return of capital to the investor.
No, not all rights issue are like this one. Look at the recent one by Cambridge Industrial Trust, for example.
CIT: Equity fund raising again.
Thanks AK71 for ur clear explanation..
Last qn, if I were to buy mother shares today, how and when would I be informed on my entitlement on the rights issue?
And (1) if i buy the rights issues, am I only able to pay for the rights issue at local banks ATM? (2) if I decide not to buy, then how do I sell my entitlement on hand?
A few days after XR (1 Dec), you will get a package from the CDP to say how many nil-paid rights you are getting.
You could pay for the rights at ATMs of participating banks or buy a cashier's order and drop off the acceptance form/envelope. Detailed instructions would be given to you in the package from CDP mentioned in para 1.
If you decide not to accept and pay for the rights given to you, you could sell them when nil-paid rights start trading on 8 Dec in the stock market just like any other shares.
Thank you. I cramped a few so as not to trouble you again. Otherwise, maybe you can share where did you obtain these specific information on the rights issues from, so I would read it up myself.
All announcements pertaining to shares traded on the SGX could be found on SGX's website. I am attaching the link below for your easy reference.
2) go to ATM on or after the 17th Dec to pay for my rights issue entitlement.
I agree the fundamentals look good and the rerating of I'sia is another plus. My personal risk is increasing my stake further by taking up my rights given that my exposure is pretty large -just to share, not to boast. Thks once a again! kingFisher.
If you are worried that your exposure to this REIT might be too big, you could always sell your nil-paid rights when they start trading. Just have to give your broker a call or go online when you are overseas, I guess.
You could also accept and pay for your rights units anytime when the nil-paid rights are trading, I guess. Last day of trading being 16 Dec. Then, sell the rights units on or after 30 Dec. Could be higher than 70c/unit.
Now, the indicative time table by First REIT did not give a deadline for the acceptance and payment of your rights units. So, I am not sure when is the deadline but the close of rights issue is on 22 Dec.
The rights are in CDP A/C today.
Lets see how much excess we can cheong for.
I would like to invest in this reit. Can i still go in and buy this share? what price would you recommend and what will be the yield like?
I cannot recommend any specific entry prices although I believe anything under 70c is attractive.
After a very very long wait.


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text:
Off Beat (br: Policial por Acaso) é um filme estadunidense de 1986, do gênero comédia romântica, dirigido por Michael Dinner.

Sinopse
Joe é um bibliotecário que nunca havia feito nada de interessante em sua vida. Seu amigo Abby é policial e foi convocado para dançar em um evento da prefeitura juntamente com outros colegas. Abby pede a John que o substitua, ele aceita e começa a ensaiar. O sujeito, então, se envolve com uma policial do grupo e tenta contar a verdade a ela, mas só consegue se livrar do disfarce quando evita um assalto e torna-se um herói.

Reação crítica
Em sua revisão de 11 de abril de 1986, Roger Ebert do Chicago Sun-Times deu a Off Beat três estrelas e meia de um possível quatro, descrevendo-a como uma das melhores comédias do ano.

Filmes dos Estados Unidos de 1986
Filmes de comédia romântica dos Estados Unidos
Filmes em língua inglesa
Filmes com trilha sonora de James Horner
Filmes de dança


text:
With: Jean-Louis Trintignant, Françoise Fabian, Marie-Christine Barrault, Antoine Vitez
Written by: Eric Rohmer
Directed by: Eric Rohmer
Language: French, with English subtitles
My Night at Maud's (1969)
Maud Squad
Eric Rohmer's best films were largely about the intellectualization of emotion, with characters feeling their way around relationships via their tumbling, thoughtful words. The third in Eric Rohmer's "Six Moral Tales" series — though released after the fourth entry, La Collectionneuse — My Night at Maud's is more deliberate, more concrete, and less fluid than his later works; it's more a study than an observation, but it reveals a brainy filmmaker first discovering ways to appeal to the heart. New in town, Catholic Jean-Louis (Jean-Louis Trintignant) attends church and spots a pretty girl (Marie-Christine Barrault) across the aisle. Later, he bumps into an old friend, Vidal (Antoine Vitez); they talk about Pascal's "wager" about believing in God. Vidal invites Jean-Louis to visit a friend of his, Maud (Françoise Fabian). Talk of faith and love continues. It snows, and Vidal reluctantly leaves, but Maud convinces Jean-Louis to stay the night. They sleep together, without sex. But somehow the encounter emboldens Jean-Louis and he is able to speak to the mystery girl, as well as meeting again with Maud and flirting with her. Rohmer ends the discussion with a jump to five years later, on the beach. The black-and-white cinematography by Nestor Almendros tends to emphasize a kind of bleakness of exterior, and a spareness of interior, perhaps re-affirming Pascal, suggesting that color and wonder lie in another life.
Claire's Knee was next in the series.


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text:
Vintage Everyday
Bring back some good or bad memories
16 Amazing Black and White Photographs That Capture the Sweetest Moments of Famous Dads With Their Kids
June 16, 2012 1940s, 1950s, 1960s, celebrity & famous people, children & youth, family, life & culture
They are famous, but with their kids, they are normal people. These interesting photos show famous dads playing with their children in the past.
Orson Welles, wife Rita Hayworth and daughter Rebecca at home in 1945. (Peter Stackpole—Time & Life Pictures/Getty Images)
Kirk Douglas hugs his son Michael in 1949. (Lisa Larsen—Time & Life Pictures/Getty Images)
Humphrey Bogart and son Stephen in 1952. J.R. (Eyerman—Time & Life Pictures/Getty Images)
Charlton Heston lifts his two-month-old son, Fraser, who is portraying the baby Moses during filming of The Ten Commandments in 1955. (George Silk—Time & Life Pictures/Getty Images)
Senator John F. Kennedy with daughter Caroline in 1958. (Ed Clark—Time & Life Pictures/Getty Images)
Desi Arnaz cheers on the Dodgers while sitting next to his young son, Desi Jr., and child actor Richard Keith who played "Little Ricky" on I Love Lucy, 1958. (Leonard McCombe—Time & Life Pictures/Getty Images)
Dean Martin with his son, Ricci, at home in 1958. (Allan Grant—Time & Life Pictures/Getty Images)
Vice President Richard Nixon and daughter Julie at a ballgame, 1958. (Hank Walker—Time & Life Pictures/Getty Images)
Tony Curtis smiles at his daughter, Jamie Lee, in 1959. (Allan Grant—Time & Life Pictures/Getty Images)
Richard Burton and his future stepdaughter, Liz Taylor and Mike Todd's daughter Liza, in 1962. (Paul Schutzer—Time & Life Pictures/Getty Images)
Steve McQueen kisses his daughter Terry goodnight in 1963. (John Dominis—Time & Life Pictures/Getty Images)
Sammy Davis Jr. with his son Mark in 1964. (Leonard McCombe—Time & Life Pictures/Getty Images)
Dustin Hoffman with his daughter Karina, 1969. (John Dominis—Time & Life Pictures/Getty Images)
Jack Nicholson plays with his daughter, Jennifer, on the deck of his home overlooking Franklin Canyon, Los Angeles, 1969. (Arthur Schatz—Time & Life Pictures/Getty Images)
Donald Sutherland with his son, Kiefer, in 1970. (Co Rentmeester—Time & Life Pictures/Getty Images)
Robert Redford and his son, David, in Utah in 1970. (John Dominis—Time & Life Pictures/Getty Images)
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Photographers' Brave Final Shots of the 1980 Mount St. Helens Eruption
Last pictures from Robert Landsburg as the eruption of Mt St Helens beared down on him. Knowing he would die, he put his camera in his backp...
30 Cool Pics That Capture Naughty Ladies of the 1950s
A cool photo collection that shows what naughty ladies looked like in the 1950s. They were probably funny but rebellious.
30 Beautiful Photos of Joyce Taylor in the 1950s and '60s
Born 1937 in Taylorville, Illinois, American actress Joyce Taylor sang in amateur shows at age 10 and turned professional at 15, signing wit...
Conversational Pits of the 1960s and 1970s
Conversation pits were typically accessed by a small staircase and filled with modular seating that could be arranged in multiple ways, such...
Mugshot of a Young Axl Rose in July 1980
An 18-year-old Axl Rose posed for the Lafayette, Indiana police mug shot in July 1980. This was one of the first of many misdemeanor bust fo...
33 Amazing Photos Capture Street Scenes of New York in the 1910s
New York City during the 1910s was a ball of motion with no signs of slowing down. The city grew and evolved with every passing year. In 191...
30 Fabulous Photos of a Young Barbi Benton in the 1970s and '80s
Born 1950 as Barbara Lynn Klein in New York City, Barbi Benton began to model at the age of 16, and at age 18 took a job with Playboy to ap...
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text:
Events, Music, Washington Park
Some Blue Notes, but in Harmony
by Ari Feldman • March 1, 2013
For those who seek the Brown Derby Jazz Revue, it's kind of hard to find. Playing on Prairie Avenue just south of 51st Street, the series is nestled inside the King Tut Room of the Great Lakes Elks Lodge, a venue equal parts Valois Cafeteria and Room 43. With a small cash bar and a pool table in the back, the King Tut Room has a divey feel while retaining the cool atmosphere of a jazz club–the chatter level stays high during the acts, and if it's your first time at the Revue, nearly everyone will want to meet you and ask why it's taken you so long to come out.
Last Thursday night the main guest didn't show–perhaps due to the expected snowstorm–so the audience was treated to a quartet led by an enthusiastic xylophone player. Sandra Bivens, one of the series' main organizers (herself a former recording artist), and fellow organizer Senabella Gill, who records under the moniker The Bronzeville Diva, took turns singing their favorite jazz standards, and then ushered in the jam session portion of the evening.
The Revue is a part of a much broader effort to reignite the area surrounding the lodge, with music at the movement's center. Once located on Indiana Avenue, the Brown Derby was a hot spot for many well-known musicians from back in the day: Duke Ellington, Cab Calloway, and Billie Holiday are just a few of the legends the Revue hosted. Referred to as "The Birdland of Chicago" by Senabella Gill, the old venue was a community hot spot as well. By bringing back the Revue, Bivens hopes to strengthen the community and remind it of its cultural heritage. "This is just something we think needs to be done in the neighborhood," she said.
The new Revue is envisioned as a potential jumping-off point for up-and-coming musicians from the South Side as well. Local professionals often show up to the concerts–Thursday nights at 8pm–to get a chance to play with everyone afterwards, and all ages and abilities are welcome and appreciated. "If you really want to learn the art, you gotta do the 'chitterling serving,'" Sandra told me–meaning if you want to be great, you have to put in the time with the seasoned professionals.
Though most of the players were older community figures, the feel of the Revue is timeless–the past blends seamlessly into the present just as jazz and conversation fill the room. Hopefully this feeling will help bring the music back to some of its former splendor on the South Side, where the jazz scene has suffered in recent years from the closing of clubs like the South Loop's Velvet Lounge. But as Revue organizer and actor James Ellis told me, "With music in common, we can help bridge the gap–it's something we have in common. With great music you can inspire people. Chicago is a major force [in jazz music], and we're trying to reignite that force."
Tags: Brown Derby Jazz Revue Great Lakes Elk Lodge Washington Park
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