CHM - Compiled HTML for Microsoft files can appear damaged or unreadable. But they are not, they are often distributed in multiple "pieces" rather than a "singular" name.chm file in older Microsoft PDK, SDK and DDK documentation. (accidentally) moving only the .chm file can result in missing functions when opening the .chm file for viewing.
The image has been deliberately "blurred" to protect the rights of the publisher. However the controls and navigation pane to the Left have not been "blurred".
You will notice that The usual [Contents][Index][Search] tabs are "missing" from the tab menu.
The word "untitled" will be returned over and over in the topics list, and link nowhere.
When you recover or "move" the .chi file into the same directory as the .chm file it (automatically) indexes "on the fly" and the results are as expected (minus the "blurring" effect I added to the image).
That is the "expected" navigation controls on the Left return and are available again.
Also the "existence" of the .chi file causes a "new" file to be created when the .chm file is opened. In fact the procedure is that as soon as the .chm file is opened a compatible .chi file is searched for in the current directory and then a new .chw file is created if the directory is "writable" - this is described as a combined kwords file.. or "chw"ords file. "k" is often used to mean "Index" file in other CHM contexts.. so this could mean "Compile Help Index Words" or "Compile Help Key Words" to support the Index and Search tabs (without the extra "k").
Its further confusing that [some] in fact [many] files compiled in more recent years, especially by third party software programmers, include the index (inside) the single .chm file.
So those .chm file behave as if the .chi file were included in the current location, but are in fact "standalone".
This change in behavior really makes troubleshooting older documentation harder, especially since Compiled Help documentation (about the CHM format) is somewhat rare.. and the change in Help document formats and ramping up of Security blockades to disable and deprecate older Help file formats. -- there simply isn't a lot of care taken to "learn from the past" and "document for the future".
Note: further online research led to the tacky "political" situation between "Public" chm files and "Private" Internal Microsoft MSDN formats. HTML Help versions 1.x 2.x and 3 or 4,5 were on a very rocky road at the end of the last Century (1999-2000) and after announcing and "using internally" a new version of CHM they basically cancelled and did not deliver. The result was a split or division between versions of CHM 1.x and 2.x (which was never released outside Microsoft). The MSDN Library released on CDROM would use this new "splitted" CHM/CHI/CHW version.. and apparently without formal notice the SDK, DDK documentation.. and perhaps Microsoft Press CDROMs.. but it was never formally documented.
Some people took to reverse engineering the new pseudo-unoffical/official format and came up with tools and "ways" of adding their own .CHM documents to the MSDN versions.. before the later versions of CHM.. so the internal strife were recognized and "patterned" around.. which is nothing new for this era with the company.
The CHM format appears abadonned, but maintained in more and more projects, outside the oversight of Microsoft.. and as they do not maintain much of a corporate history.. perhaps the less involvement and further they get from it the better. But the standard for CHM while not open, or well documented lives on. With only .MD or HTML markup showing a hint at replacing it on GitHub.


What a couple of month it's been… The launch of the new 2018 Vintage Wines has seen us pour the new BAIE Sauvignon Blanc, Pinot Gris, Rosé and Shiraz at the Winter Shiraz Festival, 360Q in Queenscliff, Barwon Heads Wine Store, Bottles and Barrels, Randalls and more to come – and the feedback has been overwhelming – people were happy to see all their favourites back, with the quality and style they have come to expect.
We are so happy that BAIE is back on the shelves at all good local wine stores and can't wait for you to try them (if you haven't already)! And if you want a jump on getting some BAIE delivered to your door – check out our 'I Want Them All' box (and if you are a member of our rewards club BAIE Insider delivery is free). This box is a beautiful gift or just for yourself ensuring you have one of each of our wines available when the moment calls for it – Sunday Roast Shiraz, Seafood Saturday Sauvignon Blanc, Rosé all Day or Pinot Gris with your besties – we've got you covered.
Sounds too good to be true – well it's not… We've had loads of people join up and they are already earning rewards…. We think we have found the perfect way to say thank you. Head over to our page HERE to be check out more of the BAIE Wines Insider experience and sign up.


Sailor Moon is an anime series by Japanese author Naoko Takeuchi about a schoolgirl who can transform into Sailor Moon aka the leader of the Sailor Soldiers. Their mission is to battle against villains who are trying to steal the Silver Crystal and destroy the Solar System.
Sailor Mercury is one such character from the series and a member of the Sailor Soldiers. She is seen as the 'brains' of the group using her intelligence and supercomputer to help the girls get an edge during battles.
Yesterday on the blog we showed you how to create a Sailor Moon costume, it only made sense to keep the theme going so today we'll be doing a Sailor Mercury Costume.
So if Sailor Mercury is your favorite member of the gang, this post is for you! As it happens their outfits are fairly similar so the instructions won't be much different. Without further ado let's get into it.
The first area to tackle is Mercury's hair, she has short blue hair in a bob style. Chose between wearing a wig such as the ones above, or dye your hair blue and style/cut into shape. Use spray dye if you'd like a less permanent change.
An optional accessory is Mercury's head piece. You can check out the one we've picked out for you above or make your own using a yellow headband or piece of card wrapped around your forehead with a blue plastic gem glued onto the center. As a last resort you could even draw it on following the makeup guide below.
Now let's move onto the cosplay outfit itself. As I said above this outfit is practically identical to Sailor Moons, the only difference is the colorscheme. This cosplay set has everything you'll need to transform into this character including: dress, tiara, chocker, two bowknots, pair of gloves and stockings.
You could easily pick up these same items from your local thrift store to put together this outfit yourself. A white short sleeved nautical themed shirt, blue skirt, white gloves, a blue bow. Use scrap blue fabric to create the arm bands and neck chocker. Simply add a pair of blue boots such as the ones below to complete your outfit (pick these up at the thrift store when you're looking for the other items).
Finish off with a pair of bright blue Gogo boots. Pick these up from the link above or find them in your local thrift store for a few dollars.
Although it is completely optional, makeup would help bring the whole look together. A little blue eye shadow, a cat wing and blue contacts will go a long way. For a detailed rundown check out the video. The artist even shows you how to draw on the headband so you don't have to buy one.
This would make the ideal group fancy dress idea too, if you can get a few friends or family members along with you dressed as different members of the Sailor Soldiers even better!
Before you leave be sure to check out the rest of our cosplay guides on the blog and for updates on newest posts follow us on social media.


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text:
COVID-19 Vaccine Tracker:…
COVID-19 Vaccine Tracker: How Many People Have Been Vaccinated In The U.S.? : Shots
This page is updated regularly.
The US is working to vaccinate a high percentage of its population against COVID-19 as soon as possible to stop the spread of the disease and end the outbreak in the country.
The mission becomes even more urgent as coronavirus variants emerge around the world, raising concerns that the virus could escape our efforts to control it if it is not quickly slowed to slow its spread.
Since vaccine distribution began in the US on December 14, more than 32 million doses have been administered, representing 7.8% of the total US population. This is based on federal data collected by the Centers for Disease Control and Prevention. The US currently manages around 1.3 million shots a day.
In addition to the states, the federal government distributes vaccines to four federal agencies, five US territories, and three freely associated states.
Currently, the two COVID-19 vaccines approved for emergency use each require a two-shot regimen three or four weeks apart. The vaccination is not complete until both doses have been received.
Sales strategies – along with the efficiency and fairness of the process – vary from state to state.
Getting millions of people vaccinated Order of priorityis a major logistical challenge for states. As a result, there is often a delay between the state receiving vaccine supplies and the time all shots get into people's arms.
The rate of vaccination has improved since December, but there are still millions more doses given to states than given to humans.
States receive weekly vaccine allocations from the federal government based on their total adult populations. Each state has its own plan for delivering these vaccines to its residents – through health departments, hospital systems, pharmacies, mass vaccination centers, and mobile clinics – and some states use their supplies more efficiently than others.
Some state officials have argued that the CDC numbers don't accurately reflect how efficiently they are delivering the vaccine doses received. The CDC says their data may reflect a reporting delay of up to five days.
President Biden has set himself the goal of getting 100 million rounds in the guns in the first 100 days of his term – an effort that extends from late January to April.
To accelerate efforts to vaccinate the U.S. population, the country needs more vaccines from manufacturers and more efficiency from states, Biden said.
The Biden administration is working out a deal to buy one an additional 200 million vaccine doses by Pfizer and Moderna, due to ship this summer, and plans to use the Defense Production Act to remove other bottlenecks such as B. Limited supplies of syringes or protective equipment.
Biden pledged to give the states more reliable forecasts of vaccine supply weeks in advance to help them plan. He also announced plans to increase the number of vaccines and blanket the country with thousands of new locations where people can get vaccines, such as B. Local pharmacies and vaccination centers supported by the Federal Emergency Management Agency.
Selena Simmons-Duffin, Ruth Talbot, Thomas Wilburn, and Carmel Wroth contributed to this report.
Tags: Covid19 People Shots Tracker vaccinated Vaccine
Is It Ever Okay…to Skip the Super Bowl but Keep the Super Bowl Snacks?
Razer to create 1,000 roles for new Asean HQ at one-north, Garage

redpajama_set_name: RedPajamaCommonCrawl


This all sounds fairly good on paper, right? Well let's find out how it looks in practice. Within this review, we will have a look at their drag and drop editor and see if it's any good for producing a website, blog or online shop.
On The wide range of site building alternatives, Weebly resides at the end that's comprehensive and provides everything you want to get started and develop your website. It is in contrast to solutions where you buy, install, and manage all of the"bits" of your site individually.
Using Weebly is sort of like leasing and customizing an apartment in a nice development rather than getting and owning your own residence. You're still in control of decor, cleaning, and what living-wise — however you leave the building, plumbing, safety, and infrastructure to the house owner. That point is key because there's usually a direct tradeoff between control and convenience.
All The design and functionality which are contained with Weebly work together collectively as a stage. That's what lets them own drag and drop design, design, and articles.
Site Builders as a team compete with choices like WordPress.org (which provides the free software to construct a website that you have & control — see my own WordPress setup guide here) all the way to choices like typing actual HTML code into a text file. Make sense? Awesome, let's dive into the Weebly review.
One Other quick aside — a disclosure — I receive referral fees from all of the companies discussed in this post. My remarks & research are based on my experiences like a paying client or consultant to a paying client.
You'll find that components snap into position And organize themselves perfectly on the webpage. Other solutions, such as Wix, forego the grid system, so it is quite possible to end up with overlapping elements. Together with Weebly, no probability of that occurring.
Working with text is also a breeze in Weebly. You just click what you want to edit and type your words from the box. Some other options use"entrance masks" that are a bit more abstract and not necessarily easy to utilize.
So are there Any downsides? This depends. If you would like more freedom with your designs, then you might feel frustrated with the rigid grid system. You should go to get Wix. This competition also has an automated solution (Wix ADI) that may build the website for you by itself. You can possibly shave a few minutes of your website building time.
Additionally, there are two things we'd like to see. First is a worldwide reverse button. It is possible to undo what you type in text boxes, but it would be nice to erase mistakes once you add or move elements. Secondly, Weebly does not have a general media database which keeps all of your pictures. You're going to need to re-upload images for each and every element that requires them.
Let us get one thing out of the way . if You're an advanced search engine optimization specialist who absolutely needs to rank #1 on search engines for a really competitive keyword, you might have a difficult time with Weebly. It is not impossible, but there are limitations.
· Certain pages (groups and product pages) add a compulsory string for your URL. You get things like www.yoursite.com/store/p1/my-product/yellow. Not a huge issue unless your site isn't in English. Same with the website posts, they'll have'/site /' in the URL structure, which can't be changed.
Just as we Know, very safe. The business takes security very seriously. They market strong passwords, and offer SSL encryption on all plans. Even the free tier will operate on https that delivers an extra layer of security. Especially crucial for onsite personal data exchange (e.g. credit card or email address).
Unfortunately, we wish Weebly provided more in the way of backup and restore systems. You've got to look after it manually by conserving your website as a .zip file frequently. And there is no restore function in case disaster strikes. Wix, for instance, monitors new adjustments and lets you jump back in time to a previous version of your site.
We have a Detailed post about Weebly's templates where you can read the key pros and cons. However, we wish to give you a quick summary of the main features here.
The First thing to note is that Weebly doesn't have a ton of template designs (around 50), but you should easily be able to find one you like. There are various classes available. Online Store, Business, Portfolio, Personal, Event and Blog.
They mechanically look great on every Apparatus (by being reactive ), and they may be adapted to match your personal requirements, using the templates as a foundation. No need for you to receive a web design degree!
We'd say yes, with a caveat. It's great to Sell digital and physical products for small and medium-sized stores, but not for huge ones. Even though you can use the import and export function to manage many things, you might discover Weebly lacking in features such as massive stores.
Finally, it's worth noting that even though You can create a store with the Starter and Guru plan, updating to Business and higher makes more sense. You'll get the automatic delivery and sales tax calculator, which is extremely useful for serious shop owners. Furthermore, you won't have to cover an additional transaction fee of 3 percent.
You bet! There are no less than 300 apps in A number of categories like eCommerce, Communication, Marketing, Social, or Site Tools. Some are free, some are compensated. Some are built by Weebly, some by third party developers. For the latter, there's always an (unlikely) possibility that it may shut down a single day. Also a pity the programs made by Weebly are rather limited.
However, one thing all the apps have in Common is a super easy installation attribute. Click and bam! All programs are analyzed and will work instantly on your own website. We attempted some cool ones such as a way to include tables, event calendars, and info bars to display specific information. Our only qualm is that the quality and quantity of apps is a slightly inferior those from the Wix App Store.
Weebly supplies Hosting for all the websites which are built on their own platform. That can be good or bad, however in Weebly's situation, it is an expert. They have rapid load rates. Their websites are optimized to their own hosting. They take care of safety against spam and hackers. With business plans, they install and keep SSL across your entire site. Here is my speed test.
There Are still speed and security risks, but overall, it's an advantage for many site owners to have somebody else take care of speed, security, backups, etc.. The price tag is bundled with expert and free accounts, so it is a good value-add.
Whenever You begin some piece of software — regardless of how instinctive — there is that moment where you think"okay, what do I do today?" That process is known as onboarding, and it is also incredibly hard to execute well.
The Software manufacturer does not want to be annoying, but they also want to provide help. I really like how Weebly builds in solid onboarding and instruction not just via email drip arrangement but also via little info buttons constructed with their own platform.
One Advertised benefit of using an all-inclusive site builder is you won't have to write HTML or CSS code. You only have to drag and drop components. What you see in the builder is exactly what you receive on the site.
It's Not necessarily that simple. There's a whole lot of nuances to"drop and drag." The majority of us really mean"I want to drag and click this component and transfer it to a general place where it will seem good — you know, automatically focused, etc." Put simply, it is like playing tee-ball rather than baseball…or bowling with gutter guards up. You want to do something, but also have a bit of assistance.
With An all-inclusive platform, client support can troubleshoot and fix any issue. This is a huge benefit of site builder platforms in general, but especially with Weebly because they have telephone support.
If You conduct your own site, you've got to work out just who can fix a problem before getting in contact with them. With Weebly, you merely get in touch with them.
The Big advantage of building your own site on your host is you don't need to count on a platform's feature set. If you go the platform route, it's essential to be sure they have all the features you want and need.
Even Past the advanced requirements, Weebly also includes features like forums, subscription choices, integrated marketing options, file uploads, etc.. In addition they have eCommerce alternatives, which I'll cover individually below.
If You go the comprehensive site builder route, Weebly's feature set should offer whatever you will need for typical personal/business websites (though as we will see in the Cons section, you really do need to be especially aware of advanced options).
If You are starting a site and plan on selling a couple of things here and there or in case you have an offline presence (ie, pop-up shops) and you would like to market online, the Weebly offers a ready-made alternative with closely integrated ecommerce characteristics that should just get better.
I have Been using site builders for 20 years because the Homestead.com times and have been paying attention to the industry for the previous five decades. One overarching trend is a firm's structure pushes product investment over the marketing group or the product group.
Total Pricing is quite competitive not only compared to other comprehensive website buildersbut also with purchasing your own hosting. Their Starter plan starts approximately $8/mo when paid up front. And they don't have the common caps of other site builders. The Guru plan adds solid features and still stays under $12/mo.
And Again — you'll notice that everything is bundled and infinite. There are no caps on webpages or storage space. And unlike competitions such as Wix, they eliminate all advertisements with the initial paid tier.
Compared To building your own website on your server and especially with other site builders, Weebly's pricing is very aggressive. Cost is not everything, however I love how they structure it.
However, Obviously, no Weebly review would be complete without studying the drawbacks. Each piece of software will have complaints. Let us look at 3 specific cons I discovered.
There's No method to add custom content forms (except inside a single page). If you're planning a large site (like hundreds of webpages ), the content within Weebly would require a private system to maintain it all sorted and easily accessible.
The Last big disadvantage of Weebly is that moving to a different platform is difficult. If you want to move someplace else, such as your own WordPress powered website, migrating your articles and redirecting your URLs are going to be a challenging process.
Since Weebly allows for HTML editing, most marketing tools and attributes can be added to your site. But since you still don't have 100% control on your website & server — it can be difficult and/or impossible to add advanced marketing tools like an EV SSL, custom email collection tools, custom analytics packages, custom social stocks, special Schemas and A/B testing computer software.
A bonus for Weebly is their eCommerce functionality. You can sell products from the Weebly site without changing platforms or performing some special developments. It fits in seamlessly and has strong functionality.
It is Ideal for websites which are primarily lead-generation, informational, etc also want to sell a few goods. Additionally, it is a good fit for anyone testing out products before going into a long-term stage. It is not a long-term match for sites that are eCommerce-first. For all those, an online store you own with WordPress + WooCommerce or a specialization eCommerce platform like Shopify (inspection ) or even Bigcommerce (review) would be a better fit.
If You're wanting to construct a long-term articles or direct generation site, then I would consider WordPress.com (for articles ) or Wix (for general drag & drop) rather than Weebly. Even if Weebly meets your needs today, they may not in the future.
When we first started testing Weebly many Years past, it was just another website builder. That has completely changed. Weebly has evolved into an outstanding website building tool that is far better than most competitors. It is easy, uncluttered and easy to use — which is exactly what individuals with limited technical abilities need in regards to making their own internet presence.
Obviously, it's not 100% perfect. We'd like To see a bit more templates, for instance. Finding an email address attached to a own domain name is also a bit pricey, as they urge G Suite, which costs $5 per month, per user. (Although there are workarounds, as you can see in the FAQ under ).
But all in all, Weebly reaches the top of our list of website builders. Their ease of use combined with cool tools such as the iOS or Android app for editing your site on the move, or the amount of add-ons out there from the program centre makes it robust, and fun to use.


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Frontiers in Clinical Drug Research - CNS and Neurological Disorders
Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology.
The sixth volume of this series features reviews that cover the following topics:
- Depression, Insomnia and Atypical Antidepressants
- Combination Therapy of Hypothermia for Hypoxic Encephalopathy in Neonates
- Development of A "Theranostic Nano-Bullet" for Tinnitus
- Dexmedetomidine: From Basic Science to Clinical Application of Brain Protection
- Protein Misfolding, Aggregation, Amyloid Formation in Neurodegenerative Diseases
Frontiers in Clinical Drug Research - CNS and Neurological Disorders presents recent important developments in the treatment of central nervous system (CNS) and nerve disorders. The book is a valuable resource for pharmaceutical scientists, postgraduate students and researchers seeking recent information for developing clinical trials and devising research plans in the field of neurology. The chapters are written by eminent authorities in the field. The contents of this volume cover recent researches on depression and insomnia, combination therapy of hypothermia, tinnitus, and protein misfolding.
I hope that the readers will find these reviews valuable and thought provoking so that they may trigger further research in the quest for new and novel therapies against neurological disorders.
I am grateful for the timely efforts made by the editorial personnel, especially Mr. Mahmood Alam (Director Publications), and Mr. Shehzad Iqbal Naqvi (Senior Manager Publications) at Bentham Science Publishers.
Atta-ur-Rahman, FRS


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Archaeologists discover proof of wetlands, ancient life on the Utah Test and Training Range
By Todd Cromar, 75th Air Base Wing Public Affairs / Published July 22, 2016
PHOTO DETAILS / DOWNLOAD HI-RES 1 of 7
Archaeologists excavate a site on the Utah Test and Training Range, July 13, 2016. The team found tools, charcoal, water fowl bone fragments, and tooling flakes, which provide evidence of wetlands and human presence in the area more than 12,000 years ago. (U.S. Air Force photo by Todd Cromar)
Eric Gingerich, foreground, and Kelly McGuire, both with Far Western Anthropological Research Group, work at a dig site on the Utah Test and Training Range, July 13, 2016. Artifacts found at the site included water fowl bones, seeds, and a large spear tip. (U.S. Air Force photo by Todd Cromar)
Daron Duke, Far Western Anthropological Research Group project leader, directs a team of archaeologists at a dig site on the Utah Test and Training Range, July 13, 2016. Recently, the team discovered a 12,300-year-old hearth—an archaeological "feature"—and artifacts, which they have been excavating for two weeks. (U.S. Air Force photo by Todd Cromar)
D. Craig Young, Far Western Anthropological Research Group geoarchaeologist, talks with media while team members excavate an archaeological site on the Utah Test and Training Range, July 13, 2016. The site, located on Utah's West Desert, has provided artifacts which archaeologists believe point to the presence of wetlands and humans more than 12,000 years ago. (U.S. Air Force photo by Todd Cromar)
Daron Duke, Far Western Anthropological Research Group project leader, carefully cleans a large spear tip before removing it from the ground at an archaeological dig site on the Utah Test and Training Range, July 13, 2016. The spear tip was one of the principle artifacts found at the site last week, and archaeologists working there believe early humans could have used it to hunt mammoths or large bison in the area thousands of years ago. (U.S. Air Force photo by Todd Cromar
Lindsey Daub, Far Western Anthropological Research Group staff archaeologist, works at an archaeological dig site on the Utah Test and Training Range, July 13, 2016. Daub and her colleagues have found tools, charcoal, water fowl bone fragments, and tooling flakes, which provide evidence of wetlands and human presence in the area more than 12,000 years ago. (U.S. Air Force photo by Todd Cromar)
Daron Duke, left, and Kelly McGuire display a large spear tip removed from an archaeological dig site July 13 at the Utah Test and Training Range. Duke and McGuire are archaeologists with Far Western Anthropological Research Group. Hill Air Force Base and the Utah State Historic Preservation Office have worked for several years exploring, discovering, and preserving historical and cultural artifacts on the UTTR. (U.S. Air Force photo by Todd Cromar)
UTAH TEST AND TRAINING RANGE, Utah --
Recently, a team of archaeologists working on the Utah Test and Training Range under the direction of the Hill Air Force Base cultural resource program discovered a 12,300-year-old hearth—an archaeological "feature"—and artifacts, which tell the story of North America's earliest inhabitants and of a very different landscape from that of today.
Traveling through Utah's West Desert and the Great Basin region today, the desolate landscapes stretch for miles in every direction, making it difficult to imagine lush, thriving wetlands. However, this discovery further confirms that the region was once a vast expanse of rivers, streams, and marshes, inhabited by many varieties of plants and animals. Additionally, the discovery proves that people have had a long presence in the area.
In compliance with Section 106 of the National Historic Preservation Act, the Air Force for years has worked very closely with the Utah State Historic Preservation Office to explore, discover, and preserve historical and cultural artifacts on the UTTR.
Anya Kitterman, Hill AFB archaeologist and cultural resource manager, said that the preservation efforts are accomplished by proactively doing archaeological surveys in areas not previously visited.
"We work to focus these surveys on areas which have a higher potential for archaeological resources," she said. "This is based on previous surveys, a probability model developed to identify those areas with the most likelihood of archaeological resources based on past environments, and previous research."
She continued, "Hill AFB contracted Far Western (Far Western Anthropological Research Group) for the 2015 summer field survey season to survey several thousand acres which were chosen based on the above criteria, and the hearth site was one of many sites where numerous artifacts were found. It is, however, by far the most significant."
Sarah Rice, Far Western senior archaeologist, talked about the hearth site July 13, while continuing the excavation here.
"In the first week, we have collected over 60 items around the feature," she said. "We found tools, charcoal, pieces of duck and goose bones, tooling flakes…very unique. In fact, something like this has never been found in North America before!"
The unique circumstances and variables surrounding this recent discovery took thousands of years to come together. Erosion by wind and water uncovered the artifacts after more than 12,000 years. Then, trained archaeologists, combining years of local research, focused on this exact area looking for precisely this kind of feature and artifacts.
According to D. Craig Young, Far Western senior geoarchaeologist, the current excavation's location was once a wetland where people and animals gathered.
"The old river bed in Utah's West Desert is unique because it was a highly productive area for a confined period of time, from the recession of Lake Bonneville up until 8,500 years ago, approximately," he said. "There is a window of time that this area was an oasis marshland, and people came to use this patch as the rest of this part of the Great Basin was drying out."
During their research, Young and his teammates used geologic features to reconstruct events and explain patterns over thousands of years.
"Left behind in the Paleo delta (an ancient river delta) are layers of organic marsh and decomposed plant life that was buried—we call them black mats," Young said. "These mats are now a layer of soil in this area, exposed in spots due to erosion. Researchers all along this delta are interested in black mats because they can be radiocarbon dated. They contain plant species, shell species, and fish species, which gives us a window into that environment at that time."
Daron Duke, Far Western senior archaeologist and lead for the current project, who has worked with the Air Force for 15 years, was excited about the recently discovered hearth and the story it tells.
"The reason we want to find features is because we can directly date them," he said. "This infers the artifacts are of a certain age. Otherwise it is not clear."
The significance of the find helped the archaeologists determine that people occupied the region many thousands of years ago.
"Then there are questions about the significance of these people," Duke said. "They really are the first occupants of the Great Basin that we can demonstrate. If we went from the earliest accepted date of man in the Americas, approximately 13,400 years ago, people seemed to have dispersed all across the continent within a short, 500-year timespan."
According to Duke, the first few people inhabiting this area moved around a lot.
"We do know that by the time of 13,000 years ago, 400 years after people are in North America, we get evidence of people in this area and the Great Basin," he said. "The people then seemed to be pretty transitory. They might have seen megafauna (large animals) and possibly were hunting mammoths and giant forms of bison."
Environmentally, the Great Basin has been mostly dry for about 9,000 or 10,000 years, according to Duke. Until the dry period arrived, changing geologic conditions may have led to people inhabiting the area.
"The Great Basin is now arid, but at that time it was maybe 10 to 15 degrees cooler on average, a much cooler environment," he said. "This is why there were rivers, lakes, and marshy wetland ecosystems. These people had a unique landscape for thousands of years. Toward the end of this period, for people who had the run of North America, things were drying up and this could have been one of the last places they decided to make use of."
Other significant items were found around the hearth.
"We now knew we had something unusual and important, which was evidence of people!" said Duke. "The main thing of significance is we found tobacco seeds. What makes this interesting is there's no direct evidence of anybody using tobacco past 3,000 years ago, and this was 12,000 plus years ago! It's also a new world plant, not a plant from the other side of the world, so obviously this raises a lot of questions."
Duke continued, "Now that we have dug a bigger grid around the fire pit, we know that the people were throwing food refuse around and dropping some down on the ground. We then discovered a buried point, or big spear tip, right next to the feature."
Young expanded on the spear tip's significance.
"Here in this location, we see possibly a more generalized diet of several species of ducks, which is not surprising [for people] working and living in a wetland," he said. "Also of significance is that these people were carrying their big game tool kits, as evidenced by the big point found right next to the hearth. It's about 8 to 10 centimeters long and one wouldn't think that was being used to capture ducks. It could have been used to process the water fowl, but those large points tend to be associated with hunting of large game."
Kitterman said Hill AFB will continue to focus on identifying and protecting resources here.
"We hope to undertake further data recovery at additional sites that are at risk from natural processes, such as erosion, in the near future," she said. "This site, and other similar sites nearby, may change the way we approach cultural resource protection and management in the south range and will help us gain further insight into the prehistoric fabric that makes up this unique landscape."


text:
Calcium-Calmodulin-Dependent Protein Kinases MeSH Descriptor Data 2023
Calcium-Calmodulin-Dependent Protein Kinases
D08.811.913.696.620.682.700.125
general or unspecified; prefer specifics
A CALMODULIN-dependent enzyme that catalyzes the phosphorylation of proteins. This enzyme is also sometimes dependent on CALCIUM. A wide range of proteins can act as acceptor, including VIMENTIN; SYNAPSINS; GLYCOGEN SYNTHASE; MYOSIN LIGHT CHAINS; and the MICROTUBULE-ASSOCIATED PROTEINS. (From Enzyme Nomenclature, 1992, p277)
Ca(2+)-Calmodulin-Dependent Protein Kinase
Calcium-Calmodulin-Dependent Protein Kinase
Calcium-Calmodulin-Dependent Protein Kinases, Multifunctional
Calcium-Calmodulin-Dependent Protein Kinases, Restricted
Calmodulin-Dependent Multiprotein Kinase
Calmodulin-Dependent Protein Kinase
Calmodulin-Dependent Protein Kinases
Calmodulin-Kinase
Cam-MPK
Multifunctional Calcium-Calmodulin-Dependent Protein Kinase
Multifunctional Calcium-Calmodulin-Dependent Protein Kinases
Restricted Calcium-Calmodulin-Dependent Protein Kinase
Restricted Calcium-Calmodulin-Dependent Protein Kinases
Registry Number
EC 2.7.11.17
Related Numbers
Previous Indexing
Protein Kinases (1990-1993)
2008; see CA(2+)-CALMODULIN-DEPENDENT PROTEIN KINASE 1998-2007; see CALMODULIN-DEPENDENT PROTEIN KINASES 1994-1997 & PROTEIN KINASES 1990-1993; CALMODULIN-DEPENDENT MULTIPROTEIN KINASE was indexed under PROTEIN KINASES 1989-2007
administration & dosage (AD)
adverse effects (AE)
analysis (AN)
antagonists & inhibitors (AI)
biosynthesis (BI)
chemical synthesis (CS)
deficiency (DF)
isolation & purification (IP)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Activin Receptors [D08.811.913.696.620.682.700.062]
AMP-Activated Protein Kinase Kinases [D08.811.913.696.620.682.700.074]
AMP-Activated Protein Kinases [D08.811.913.696.620.682.700.085]
Ataxia Telangiectasia Mutated Proteins [D08.811.913.696.620.682.700.097]
Aurora Kinases [D08.811.913.696.620.682.700.103]
Autophagy-Related Protein-1 Homolog [D08.811.913.696.620.682.700.108]
Bone Morphogenetic Protein Receptors [D08.811.913.696.620.682.700.109]
Calcium-Calmodulin-Dependent Protein Kinases [D08.811.913.696.620.682.700.125]
Calcium-Calmodulin-Dependent Protein Kinase Kinase [D08.811.913.696.620.682.700.125.049]
Calcium-Calmodulin-Dependent Protein Kinase Type 1 [D08.811.913.696.620.682.700.125.100]
Death-Associated Protein Kinases [D08.811.913.696.620.682.700.125.387]
Elongation Factor 2 Kinase [D08.811.913.696.620.682.700.125.425]
Myosin-Light-Chain Kinase [D08.811.913.696.620.682.700.125.500]
Casein Kinases [D08.811.913.696.620.682.700.140]
Checkpoint Kinase 1 [D08.811.913.696.620.682.700.143]
Cyclic Nucleotide-Regulated Protein Kinases [D08.811.913.696.620.682.700.150]
DNA-Activated Protein Kinase [D08.811.913.696.620.682.700.250]
Doublecortin-Like Kinases [D08.811.913.696.620.682.700.275]
eIF-2 Kinase [D08.811.913.696.620.682.700.300]
G-Protein-Coupled Receptor Kinases [D08.811.913.696.620.682.700.364]
Germinal Center Kinases [D08.811.913.696.620.682.700.397]
Glycogen Synthase Kinases [D08.811.913.696.620.682.700.429]
I-kappa B Kinase [D08.811.913.696.620.682.700.494]
Interleukin-1 Receptor-Associated Kinases [D08.811.913.696.620.682.700.526]
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 [D08.811.913.696.620.682.700.534]
Lim Kinases [D08.811.913.696.620.682.700.542]
MAP Kinase Kinase Kinases [D08.811.913.696.620.682.700.559]
Mitogen-Activated Protein Kinase Kinases [D08.811.913.696.620.682.700.565]
Mitogen-Activated Protein Kinases [D08.811.913.696.620.682.700.567]
Myotonin-Protein Kinase [D08.811.913.696.620.682.700.576]
NIMA-Related Kinases [D08.811.913.696.620.682.700.581]
Oncogene Protein v-akt [D08.811.913.696.620.682.700.586]
p21-Activated Kinases [D08.811.913.696.620.682.700.596]
Phytochrome A [D08.811.913.696.620.682.700.606]
Positive Transcriptional Elongation Factor B [D08.811.913.696.620.682.700.626]
Proline-Directed Protein Kinases [D08.811.913.696.620.682.700.646]
Protein Kinase C [D08.811.913.696.620.682.700.725]
3-Phosphoinositide-Dependent Protein Kinases [D08.811.913.696.620.682.700.745]
Protein Kinase D2 [D08.811.913.696.620.682.700.750]
Proto-Oncogene Proteins c-akt [D08.811.913.696.620.682.700.755]
Proto-Oncogene Proteins c-bcr [D08.811.913.696.620.682.700.759]
Proto-Oncogene Proteins c-pim-1 [D08.811.913.696.620.682.700.776]
Pyruvate Dehydrogenase Acetyl-Transferring Kinase [D08.811.913.696.620.682.700.783]
Receptor, Transforming Growth Factor-beta Type I [D08.811.913.696.620.682.700.789]
Receptor, Transforming Growth Factor-beta Type II [D08.811.913.696.620.682.700.795]
Receptor-Interacting Protein Serine-Threonine Kinases [D08.811.913.696.620.682.700.801]
rho-Associated Kinases [D08.811.913.696.620.682.700.814]
Ribosomal Protein S6 Kinases [D08.811.913.696.620.682.700.862]
Serine-Threonine Kinase 3 [D08.811.913.696.620.682.700.897]
TOR Serine-Threonine Kinases [D08.811.913.696.620.682.700.931]
Vacuolar Sorting Protein VPS15 [D08.811.913.696.620.682.700.965]
WNK Lysine-Deficient Protein Kinase 1 [D08.811.913.696.620.682.700.982]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Protein Serine-Threonine Kinases [D12.776.476.563]
Activin Receptors [D12.776.476.563.062]
AMP-Activated Protein Kinase Kinases [D12.776.476.563.074]
AMP-Activated Protein Kinases [D12.776.476.563.085]
Ataxia Telangiectasia Mutated Proteins [D12.776.476.563.097]
Aurora Kinases [D12.776.476.563.103]
Autophagy-Related Protein-1 Homolog [D12.776.476.563.108]
Bone Morphogenetic Protein Receptors [D12.776.476.563.109]
Calcium-Calmodulin-Dependent Protein Kinases [D12.776.476.563.125]
Calcium-Calmodulin-Dependent Protein Kinase Kinase [D12.776.476.563.125.049]
Calcium-Calmodulin-Dependent Protein Kinase Type 1 [D12.776.476.563.125.100]
Death-Associated Protein Kinases [D12.776.476.563.125.387]
Elongation Factor 2 Kinase [D12.776.476.563.125.425]
Myosin-Light-Chain Kinase [D12.776.476.563.125.500]
Casein Kinases [D12.776.476.563.140]
Checkpoint Kinase 1 [D12.776.476.563.143]
Cyclic Nucleotide-Regulated Protein Kinases [D12.776.476.563.150]
DNA-Activated Protein Kinase [D12.776.476.563.250]
Doublecortin-Like Kinases [D12.776.476.563.275]
eIF-2 Kinase [D12.776.476.563.300]
G-Protein-Coupled Receptor Kinases [D12.776.476.563.364]
Germinal Center Kinases [D12.776.476.563.397]
Glycogen Synthase Kinases [D12.776.476.563.429]
I-kappa B Kinase [D12.776.476.563.494]
Interleukin-1 Receptor-Associated Kinases [D12.776.476.563.526]
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 [D12.776.476.563.534]
Lim Kinases [D12.776.476.563.542]
MAP Kinase Kinase Kinases [D12.776.476.563.554]
Mitogen-Activated Protein Kinase Kinases [D12.776.476.563.565]
Mitogen-Activated Protein Kinases [D12.776.476.563.567]
Myotonin-Protein Kinase [D12.776.476.563.576]
NIMA-Related Kinases [D12.776.476.563.581]
Oncogene Protein v-akt [D12.776.476.563.586]
p21-Activated Kinases [D12.776.476.563.596]
Phytochrome A [D12.776.476.563.606]
Positive Transcriptional Elongation Factor B [D12.776.476.563.626]
Proline-Directed Protein Kinases [D12.776.476.563.646]
Protein Kinase C [D12.776.476.563.725]
3-Phosphoinositide-Dependent Protein Kinases [D12.776.476.563.745]
Protein Kinase D2 [D12.776.476.563.750]
Proto-Oncogene Proteins c-akt [D12.776.476.563.755]
Proto-Oncogene Proteins c-bcr [D12.776.476.563.759]
Proto-Oncogene Proteins c-pim-1 [D12.776.476.563.776]
Pyruvate Dehydrogenase Acetyl-Transferring Kinase [D12.776.476.563.783]
Receptor, Transforming Growth Factor-beta Type I [D12.776.476.563.789]
Receptor, Transforming Growth Factor-beta Type II [D12.776.476.563.795]
Receptor-Interacting Protein Serine-Threonine Kinases [D12.776.476.563.801]
rho-Associated Kinases [D12.776.476.563.814]
Ribosomal Protein S6 Kinases [D12.776.476.563.862]
Serine-Threonine Kinase 3 [D12.776.476.563.897]
TOR Serine-Threonine Kinases [D12.776.476.563.931]
Vacuolar Sorting Protein VPS15 [D12.776.476.563.965]
WNK Lysine-Deficient Protein Kinase 1 [D12.776.476.563.982]
Calcium-Calmodulin-Dependent Protein Kinases Preferred
Calcium-Calmodulin-Dependent Protein Kinases Preferred Term
Multifunctional Calcium-Calmodulin-Dependent Protein Kinases Narrower
A subclass of calcium-calmodulin-dependent protein kinases that have broad substrate specificity.
Multifunctional Calcium-Calmodulin-Dependent Protein Kinases Preferred Term
Restricted Calcium-Calmodulin-Dependent Protein Kinases Narrower
A subclass of calcium-calmodulin-dependent protein kinases that have a very restricted substrate specificity.
Restricted Calcium-Calmodulin-Dependent Protein Kinases Preferred Term


2 Bedroom Flat For Sale in Heuwelsig Estate.
Spacious 2 bedrooms, 1 bathroom (bath and shower) property for sale in Heuwelsig, this property comes with 2 covered parking, open plan lounge and fitted tiles.
The complex offers lots of space for visitors to park at the property.
Good investment opportunity, rental income R6500-R7000 per month.


text:
Home Health Conditions
16 Silent Signs of Leukemia You Shouldn't Ignore
By Jenny G. Zhang, RD.comUpdated: Feb. 20, 2021
Leukemia, or cancer of the blood cells, can cause subtle and surprising symptoms throughout the body. Here are some clear signs you need to get checked.
What is leukemia?
Leukemia is a cancer of the blood and bone marrow, a malignancy that causes an abnormal production of certain blood cells. As the unhealthy blood cells crowd out healthy ones, blood function begins to falter and you may notice physical symptoms. The disease may get worse quickly if you have a type known as acute leukemia; the disease may progress slowly and get worse over time if you have chronic leukemia, according to the National Institute of Health.
Regardless of which type you have, if you notice a collection of these subtle signs of leukemia, see your health care provider for an evaluation.
Check out these 5 Essential Nutrition Tips for People Living With Cancer.
Fatigue and weakness are the most common symptoms for all types of leukemia, according to Mark Levis, MD, PhD, the director of the leukemia program at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center. These signs are often caused by anemia (a deficiency of red blood cells), which only compounds the physical exhaustion.
In both chronic and acute cases, you may experience a range from slight fatigue to extreme physical weakness, but in all cases, the symptoms only worsen over time. "It creeps up on people, that's the problem," says Dr. Levis.
As patients grow weaker and more fatigued, they may also experience shortness of breath that stems from anemia or, in much rarer cases, masses in the chest. "They're panting, they're out of breath," says Dr. Levis. "Walking across the room might be difficult." Shortness of breath can also be a symptom of lung cancer.
Excessive or spontaneous bruising
Unexplained bruises without any physical trauma may be a sign of leukemia, according to Pamela Crilley, DO, chair of the department of medical oncology at the Cancer Treatment Centers of America and chief of medical oncology at the Eastern Regional Medical Center. Unusual bruising is a result of a low platelet count or clotting issues, explains Dr. Levis. "You will bruise spontaneously, seemingly doing nothing," he says. "It can be anywhere, but typically they'll be on the extremities—legs and arms."
Check out the 7 Secret Signs You Might Have Cancer.
Unusual bleeding
Similar to bruising, unusual nosebleeds or bleeding in the gums, bowels, lungs, or the head may be a sign of platelet deficiency and clotting problems, which can indicate acute forms of leukemia, says Dr. Crilley.
Petechiae (small red spots under the skin caused by bleeding)
Dr. Crilley describes petechiae as: "like someone painted little red dots with a pen." The spots, which you might not notice because of their size, painlessness, and placement in the lower extremities, indicate a low platelet count. According to Dr. Levis, petechiae are typically found around the ankles because gravity results in the accumulation of bodily fluids in the lower legs throughout the day.
Swollen and enlarged gums
Although an increase in the size of the gums, also known as gingival hyperplasia, is usually only found in a small portion of acute leukemia patients, it's one of the most obvious signs of the disease. "If you have a patient with leukemia, you always look in their mouth to see if the gingiva has gotten bigger," says Dr. Crilley. The gum may look swollen, says Dr. Levis, and you nearly always feels a strange tightness in your mouth.
Do you suffer from dry mouth? Here are 6 Treatments for Dry Mouth that Actually Work!
Feeling full or bloated
One sign of chronic—and sometimes acute—types of leukemia is an enlarged spleen, which may result in a loss of appetite. You might have what's called "early satiety," according to Dr. Crilley. "Patients eat a little bit of food, they feel full quickly because the spleen is pushing up on the stomach," she says.
Check out these 5 Foods That Soothe Your Stomach.
Discomfort or pain in the upper left abdomen
An enlarged spleen caused by leukemia sometimes results in abdominal discomfort or even sharp pain. "A patient that presented to me with chronic leukemia a few weeks ago, part of his spleen had died off from spleen enlargement," says Dr. Levis. "It hurt like heck. It was a sharp pain in his abdomen." Because the spleen is located in the upper-left quadrant of the abdomen, the discomfort usually occurs there.
Fever or chills
Feverishness or chills are not the most common symptoms, typically only occurring in a quarter of acute leukemia cases and almost never in chronic leukemia cases, according to Dr. Levis. More often, frequent low-grade fevers indicate an infection and a weakened immune system, which may also be related to leukemia.
Night sweats are often caused by infections that may be linked to leukemia. "You're just drenched, and the sheets are drenched," says Dr. Crilley. "Something like that needs to be investigated."
Pounding headaches
Although not common, frequent pounding headaches may be a sign of leukemia-related anemia or even a life-threatening case of bleeding in the head.
Extreme pallor
Like headaches, fatigue, and shortness of breath, unusual paleness may be a sign of anemia in acute and some chronic leukemia patients. "If they're looking pretty pale, they're already pretty advanced and pretty sick," says Dr. Levis. "They're almost always extremely fatigued. If your red blood cell level is low enough to be pale, you're panting when you go across the room."
Achiness in the bones is a relatively uncommon but often clear symptom of both chronic and acute types of leukemia, according to Dr. Levis. Leukemic cells are made inside the bone marrow, so if you feel anything from mild achiness to extreme pain in your bones, it's best for you to seek medical attention.
Swollen lymph nodes
Check your neck, armpit, and groin areas for noticeable but painless swelling in your lymph nodes. It's normal for the glands to go up and down in size during periods of infection, but if they stay enlarged or keep growing, that may be a sign of leukemia or lymphoma, says Dr. Crilley.
Got 60 seconds? That's all you need to learn a surprising amount about your health with these at-home self exams.
Approximately one in 20 leukemia patients may have a skin rash that falls into one of two categories: a leukemia of the skin, or a rash caused by Sweet's syndrome, which is commonly associated with leukemia, according to Dr. Levis. "Leukemia of the skin almost always looks like your skin has a lump inserted inside it," he says. "A little mound starts growing. Occasionally it can be a plaque-like thing." Sweet's syndrome rashes, on the other hand, appear red and angry, similar to an allergic reaction. But although skin rashes come in all shapes and sizes, leukemia-related rashes have one thing in common: they will continue to grow and spread.
Frequent or recurring infections
If you have that one small infection that just won't go away, no matter how many antibiotics your physician prescribes, it may be time to get a complete blood count to check for abnormalities in your white blood cell, hemoglobin, and platelet levels. Abnormal white blood cell levels lead to an impaired immune system, which could explain frequent infections and the feeling of always being on the verge of the flu or infection. That, coupled with other signs such as fatigue or bruising, should be enough to send you to the doctor.
"Leukemia is always a surprise; it sneaks up on you," says Dr. Levis. Because leukemia patients can be asymptomatic or display symptoms that are common to other illnesses, it's important to get a physical examination, blood count, and bone marrow biopsy, which will characterize the exact type of leukemia and dictate the necessary treatment.


If you have enjoyed Salmon Gravlax at Diva at the Met, perhaps you'd like to try making it at home. My recipe is below.
It's just over two years since I first met Rick Burns, the fisherman and captain of the Pacific Provider.
I really enjoy what Rick stands for. He is a perfectionist: no fish that he catches stays on his deck for more than 30 minutes, even though if they did, he could catch more fish and therefore make more money. But instead, he stops fishing and processes all the fish one by one. This means he bleeds the fish properly, blast freezes them, and then glazes each fish with sea water three times. The glaze really helps to keep the moisture in the fish and stops freezer burning. Whenever I butcher one of Rick's fish, I always smile when I look at the quality of the flesh.
At Diva at the Met we use fresh salmon during the season, and out of season we use Rick's catch to give us the closest thing to fresh salmon.
Today I'm sharing a recipe for salmon gravlax that you can make at home, perfect for entertaining during the holiday season.
This is the same gravlax that we serve at Diva as a snack before our tasting menu, paired with crisp salmon skin, egg yolk puree, pickled shallots, fresh tarragon, crème fresh, oyster leaf and "nitro gravlax," which is finished gravlax in liquid nitrogen and blended in a bar blender.
At home, you can serve it simply with cream cheese and fresh dill on rye toast!
1. Place the fish skin down on a sheet of parchment paper, and then put it on a cooling rack sitting on a baking tray (make a few slices in the parchment paper as this will help any extra liquid from the cure to drip in to the tray).
2. Rub the flesh of the salmon with the rasped lemon and orange peel.
3. In a bowl mix the chopped dill with the salt, sugar and ground fennel.
4. The trick to gravlax is not putting too much cure mix on the fish at one time. The first layer should be similar to if you were going to season the fish before cooking but doubled. By applying the cure little-by-little, you'll get a perfect, even cure through the fish but you'll avoid the "gummy bear" effect.
5. Once you've applied the cure mix, cover the fish with plastic wrap and put it in the fridge to rest.
6. Every 12 hours, reapply the same amount of the cure mix. Do this for two days.
7. To serve this at home I would slice it very thin with a knife and serve it with Russian rye toast, cream cheese and fresh dill.


text:
January 11, 2017 at 10:13 AM ET by Michael Botticelli
We look back on significant actions and developments for drug policy in the U.S. in 2016
Since President Obama took office in 2009, his Administration has been working to reduce substance use and to help people live healthier lives. Over the last eight years, with the help of parents, law enforcement, public health officials, local leaders, and others in communities across the country, the Obama Administration has sought to pursue a balanced approach to drug policy, one that includes both public health and public safety efforts. In 2016, we saw several major steps forward for drug policy in the U.S., from significant new funding to address the opioid epidemic to disrupting heroin trafficking, improving prescriber education, and changing how our health care system treats substance use disorder.
President Obama secured $1 billion in new funding to address the opioid epidemic
In February, President Obama called on Congress to provide $1 billion in new funding to address the opioid epidemic, primarily by increasing access to treatment. In March, the President led a panel discussion at the National Rx Drug Abuse Summit in Atlanta on how to turn the tide on this epidemic. Throughout the year, he and National Drug Control Policy Director Michael Botticelli joined with parents and loved ones of people lost to or suffering from addiction, law enforcement officials, public health professionals, local leaders, and others to highlight the importance of better access to treatment.
Congress acted on the President's request, and on December 13, President Obama signed the 21st Century Cures Act into law, which authorized $1 billion for states to address the epidemic locally. With this law's enactment, our country will now spend similar amounts on drug-related law enforcement and substance use prevention, treatment, and recovery for the first time in history. Read more about the 21st Century Cures Act here and watch the signing ceremony here.
"This is an epidemic that can touch anybody -- blue collar, white collar, college students, retirees, kids, moms, dads…all too often, [people] feel as if they're fighting this fight alone instead of having the community gather around them and give them the resources and the access and the support that they need. So today, I could not be prouder that this legislation takes up the charge I laid out in my budget to provide $1 billion in funding so that Americans who want treatment can get started on the path to recovery and don't have to drive six hours to do it. It is the right thing to do, and families are ready for the support." – President Obama, December 13, 2016
Parity for substance use treatment
In 2015, an average of 144 people died every day from drug overdoses. Yet only 1 in 9 people who need treatment for this disease are getting it. Making sure people have access to potentially lifesaving mental health and substance use treatment is key to improving the health of our nation and helping people with these diseases live healthier, more productive lives.
The Mental Health Parity and Addiction Equity Act of 2008 eliminates certain restrictions on mental health and substance use disorder insurance coverage for plans that offer these benefits to make sure these diseases get the same level of care as other diseases like cancer, diabetes, and heart disease. Parity protections prevent plans from imposing annual visit limits, lifetime benefit caps, or higher copays for substance use disorders when they do not also exist for physical health benefits. The processes health plans use to manage care, such as preauthorization and medical necessity requirements, must also be comparable between mental health and substance use care and physical health care.
This year, President Obama convened a task force to work across government and with stakeholders to ensure that Americans are benefiting from these important mental health and substance use disorder parity protections. In October, the Parity Task Force released its report, which moves the ball forward in implementing parity and increasing the availability of mental health and substance use coverage for those who need it – including producing new guidance on parity and opioid use disorder treatment. Read more about the Parity Task Force's report here.
ONDCP provides funding for drug use prevention and law enforcement coordination in communities across the country
This summer, ONDCP directed more than $100 million in grants to communities across the country aimed at preventing drug use and disrupting drug trafficking operations. Specifically, ONDCP provided $85.9 million to the 698 Drug-Free Communities coalitions that are working to prevent youth substance use including prescription drug misuse, marijuana, tobacco, and alcohol, and $230 million to the High Intensity Drug Trafficking Areas (HIDTA) program to help Federal, state, and local authorities address emerging drug threats by coordinating drug enforcement operations, supporting prevention efforts, and improving public health and safety
In August, an additional $17 million was awarded to the HIDTAs, with $5.6 million of this funding aimed at supporting thirteen innovative projects nationwide to disrupt the trafficking of prescription opioids, fentanyl, and heroin, as well as to help train medical providers in safe prescribing practices and increase the use of the overdose reversal drug naloxone. The funding also supports an expansion of the HIDTA Heroin Response Strategy to the Atlanta/Carolinas, Michigan, and Ohio HIDTAs.
Reducing the supply of illicit opioids in the U.S.
In 2016, the Federal government took steps to reduce the supply of illicit opioids moving into and throughout the U.S. to reduce the number of heroin-involved deaths and disrupt the heroin and illicit fentanyl supply chains.
Domestic actions
ONDCP's High Intensity Drug Trafficking Areas (HIDTA) program is funding an unprecedented network of public health and law enforcement partnerships to address the heroin threat across 20 states. In addition, ONDCP, in collaboration with the National Security Council, created the National Heroin Coordination Group and tasked it to develop the Heroin Availability Reduction Plan to coordinate strategies and partnerships at the Federal, state, local, and tribal levels to reduce the availability of heroin and illicit fentanyl in the U.S.
International actions
This fall, ONDCP and the Department of State hosted the first North American Drug Dialogue to better coordinate supply reduction and public health responses to heroin and illicit fentanyl across the three countries and to chart a path forward for increased cooperation.
In September, the Administration announced enhanced measures in conjunction with the Chinese government to combat the supply of fentanyl and its analogues to the United States. The majority of fentanyl and its analogues brought to the U.S. by drug traffickers originates in China. China committed to targeting U.S.-bound exports of substances that are controlled in the United States but not in China. Additionally, the U.S. and China agreed to increase the exchange of law enforcement and scientific information with a view towards coordinated actions to control substances and chemicals of concern. The Administration will continue to work with China bilaterally and multilaterally to tighten international scheduling and improve capacity to monitor and analyze illicit synthetic drugs.
Improving prescriber education
Many physicians do not receive adequate training on pain management or substance use disorders in medical school – on average, medical schools spend fewer than 11 hours on prescriber education. This contributes to the overprescribing of opioids and to the opioid epidemic. To address this issue, in March the Centers for Disease Control and Prevention (CDC) released its Guideline for Prescribing Opioids for Chronic Pain to help prescribers safely and responsibly prescribe opioid pain medications. Hundreds of medical, nursing, and pharmacy schools pledged to incorporate this guideline into their curricula so their students will be better able to address the needs of pain patients while understanding the risks of opioid prescribing. Read about the CDC Guideline here.
The Administration has also encouraged states to set up prescription drug monitoring programs so prescribers can see what other prescriptions a patient has received. Today, 49 states have a program in place.
Macklemore visits the White House to premiere new documentary
Panel participants: Veronica Amarante, MTV News Senior Political Correspondent Ana Marie Cox, Macklemore, Director Botticelli, Lindsay Greinke, and Dr. Arthur Evans, Commissioner of the Philadelphia Department of Behavioral Health and Intellectual Disability Services.
In October, Grammy Award-winning artist Macklemore visited the White House to premiere a new MTV documentary and participate in a panel discussion on substance use disorder. The film, Prescription for Change: Ending America's Opioid Crisis, features stories of people in recovery from opioid use disorder and a conversation with President Obama about the Administration's efforts to expand access to substance use treatment services. The screening was held in conjunction with the first-ever South by South Lawn (SXSL) festival of ideas, art, and action, hosted by the White House.
Immediately following the screening a panel discussion was held that focused on ways to end the epidemic. Treatment and recovery experts, as well as people in recovery from a substance use disorder, including Macklemore, participated. Watch the discussion here.
This was Macklemore's second visit to the White House in 2016 – in May, he joined President Obama for the President's Weekly Address, which was a conversation about addiction. Watch that conversation here.
Director Botticelli addresses the UN General Assembly Special Session on the World Drug Problem
In April, Director Michael Botticelli addressed the UN General Assembly Special Session on the World Drug Problem.
In April, ONDCP Director Michael Botticelli spoke on behalf of the United States at the UN's Special Session on the World Drug Problem, the first such meeting in nearly 20 years. His statement highlighted the progress the U.S. is making in addressing drug use as a public health problem. In his remarks, he called on the countries of the world to reform their drug policies to focus more on treatment for people with substance use disorders, and to invest in the health of their citizens by working to disrupt drug trafficking organizations and supporting research to improve drug prevention and treatment outcomes for all sectors of society.
"The United States firmly believes that investing in policies and programs to help our citizens is the solution. For people with substance use disorders, we need to provide access to proven paths to recovery, such as medication-assisted treatment for opioid use disorders, a serious problem in the United States.
"And we must address the needs of underserved populations in every country such as women and children; indigenous populations; lesbian, gay, bisexual, and transgender people; rural populations; and incarcerated individuals. Drug policies must address the unique needs of all sectors of society." – Director Michael Botticelli
Overdose prevention & drug disposal efforts
Throughout the year, the Administration worked with states, chain drug stores, the medical field, and law enforcement to expand access to naloxone, the opioid overdose-reversal medication. Today, it's easier to access naloxone in almost every state than it was when President Obama took office. The Administration has also encouraged states to adopt Good Samaritan protections for people who call for help when they witness an overdose – another important tool to prevent overdose deaths.
In addition, the Administration held two more national Prescription Drug Take-Back Days in 2016 to get unused and unwanted prescription medications out of medicine cabinets before they could be misused. While most people who misuse opioid medications don't move on to use heroin, 4 out of 5 new, recent heroin users started with prescription opioids before using heroin. Throughout the 12 Take-Back Day events during the Obama Administration, the Drug Enforcement Administration (DEA) has collected more than 7.1 million pounds of unused and unwanted prescription drugs. To find a drug disposal site near you, click here.
Expanding access to effective, evidence-based care
ONDCP engages with emergency departments, health care professionals, and law enforcement officials to share strategies for helping patients transition from overdose to treatment.
ONDCP held webinars in August and December on helping individuals who have suffered an overdose access treatment. The webinars reviewed steps that hospitals and communities can take to increase the number of overdose survivors who access treatment and better identify patients with opioid use disorder in order to link them to specialty care.
The webinars highlighted innovative approaches for addressing opioid overdose and opioid use disorders in hospital emergency departments and other hospital-related settings, and outlined the Administration's response to the opioid epidemic. Click here to view the August webinar and here to view the December webinar.
White House hosts final "Making Health Care Better Series" on substance use disorder
The second of three panels during the Making Health Care Better Series Event: "Solutions for Improving Care & Recovery Support"
On November 30, the White House hosted the final "Making Health Care Better Series" on substance use disorder, bringing together leaders from diverse fields to discuss advancements in recovery, prevention, research, and access to treatment, as well as the road ahead.
To coincide with this event, the White House released a report highlighting the significant progress that has been made over the past eight years in the substance use disorder field. The report included an overview of the Obama Administration's balanced public health and public safety approach to drug policy, and its efforts to expand resources and protections for people with substance use disorders.
ONDCP engages with courts, law enforcement, and correctional facilities to expand access to evidence-based treatment for people with opioid use disorder who are involved in the criminal justice system.
The Administration has made criminal justice reform a priority. This year alone, ONDCP has worked to engage drug treatment courts, law enforcement officers, and correctional institutions on ways to divert non-violent drug offenders to treatment instead of incarceration and to encourage evidence-based treatment within correctional facilities to help people achieve and sustain recovery before and after their release.
To coincide with National Reentry Week in April, ONDCP hosted a webinar on Medication-Assisted Treatment Programs for Justice-Involved Populations. Watch the webinar here. In May, ONDCP partnered with the National Association of Drug Court Professionals (NADCP) to host a webinar on Medication-Assisted Treatment in Drug Courts. Watch the webinar here.
Deploying the Pay for Success model to address the opioid epidemic in communities
Government leaders at all levels have the responsibility to ensure taxpayer dollars are spent wisely – that they get results for the American people. This is particularly important for public health and public safety issues, such as the ongoing opioid epidemic. An Administration priority called Pay for Success (PFS) can help communities that are stretched thin respond to the epidemic.
The PFS model allows government to only pay for success, such as a decrease in the rate of opioid overdoses in a county. Meanwhile, private investors – banks, charitable foundations, or even individuals – can provide any needed upfront funds for an organization to deliver services. In this way, government does not have to fund services upfront – a helpful advantage particularly in times of tight budgets.
Communities all across the country have used Pay for Success as a way of ensuring better value for taxpayers while expanding services where there is unmet need. The Obama Administration has provided support to communities as they have developed Pay for Success programs and even helped pay for outcomes. In December, ONDCP released a Resource Guide to help states, cities, counties, and their partners learn about PFS as another tool in their toolbox. Read the Resource Guide here.
Surgeon General releases his landmark report on addiction
In November, U.S. Surgeon General Vivek Murthy released his landmark report on addiction. The Surgeon General's Report on Alcohol, Drugs, and Health is the first-ever Surgeon General's report on addiction and marks a turning point in our Nation's understanding of substance misuse and our response.
In particular, the report reinforces the public health strategies this Administration has employed to address the opioid overdose epidemic, and it paves the way for future efforts to change how we talk about substance use disorders, how we prevent drug use before it begins, and the treatment and recovery support services we offer to those with these disorders. Read the full report here.
"Our Nation is facing an opioid overdose epidemic that's unlike any public health crisis we've seen. Everywhere I go, I hear the heartbreaking stories of families and communities who are fighting this disease, as well as the stigma associated with it. To change this, we must treat substance use disorder not as a moral failing, but as a disease that people can and do recover from. I want to thank the Surgeon General for the work he's done on this issue and on this historic report." – Director Michael Botticelli
Michael Botticelli
Director of the Office of National Drug Control Policy
Follow @Botticelli44
The Final State of the Union
Watch President Obama's final State of the Union address.
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Home / National / An efficient and low-cost approach to detecting food fraud
FRAUD AND AGRICULTURE ... Comments
An efficient and low-cost approach to detecting food fraud
New model can be used to determine the origin of food in an efficient and low-cost manner
"With minor adjustments to the parameters, our model can be used to determine all plant products," says Professor Ansgar Kahmen, who led the research project. This makes it possible to simplify and speed up conventional isotope analysis by accurately simulating the regions of origin of agricultural foodstuffs. (Public Domain)
BASEL, Switzerland — Fraudulent practices in food production, especially false claims of geographical origin, cause billions of dollars in economic damage every year. Botanists at the University of Basel have now developed a model that can be used to determine the origin of food in an efficient and low-cost manner.
Strawberries from Switzerland or olive oil from Italy can be sold at much higher prices than the same products from other countries. Both the authorities and the food industry spend a great deal of time fighting false declarations of geographical origin that are assumed to cause an estimated USD 30 million to 40 billion a year in economic damage.
One method for detecting food fraud is to determine the δ18O (delta-O-18) value of a product sample, which characterizes the oxygen isotope ratio. Until now, this procedure has been highly time consuming and costly. A case of suspected fraud involved not only collecting reference data from the claimed country of origin, but also comparative data from other regions to validate or disprove the product's origin.
Cutting costs through model calculation
Basel botanist Dr. Florian Cueni has now developed a model in collaboration with Agroisolab GmbH, a company specializing in isotope analysis. This model is intended for use in simulating the oxygen isotope ratio in plants from individual regions, thereby eliminating the need for the time-consuming collection of reference data. The model is based on temperature, precipitation and humidity data and information about the growing season of a plant, all of which are available from publicly accessible databases.
Cueni tested and validated the model on a unique δ18O reference dataset for strawberries collected across Europe over 11 years. The case study has shown that the model can simulate the origin of the strawberries with a high degree of accuracy.
Wide range of uses
"With minor adjustments to the parameters, our model can be used to determine all plant products," says Professor Ansgar Kahmen, who led the research project. This makes it possible to simplify and speed up conventional isotope analysis by accurately simulating the regions of origin of agricultural foodstuffs.
The model developed by the Basel botanists is of interest to food forensics officials or the investigating authorities when it comes to the origin of confiscated drugs, for example, as well as to private forensic institutes that inspect food or serve as expert witnesses in court. NGOs such as WWF or Greenpeace are also interested – especially with regard to determining the origin of illegally logged timber – as is the food industry, which suffers reputational damage due to the sale of products that may have been falsely declared.
via EurekAlert!
For more articles concerning agricultural research, click here.
Fewer in US turn to food banks, but millions still in need
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I decided to go GOLD for my Thanksgiving tablescape this year and I just love how it turned out! Repurpose those faux pumpkins from Halloween into an elegant centerpiece and turn a few mason jars into sparkling candles. If you aren't a gold kinda person, Scotch® Expressions Glitter Tape comes in just about any color. Pick a color that will also work for your Christmas decor and keep the candles up through the holiday season. Keep scrolling for 3 easy craft projects to transform your Thanksgiving table into something that will impress your guests!
Step 1: Head to the craft aisle at Walmart and pick up Scotch® Expressions Glitter Tape, Scotch® Create Multipurpose Glue and other supplies.
Step 2: Wrap your choice of Scotch® Expressions Glitter Tape around a mason jar, wrapping 3 rows. I used gold to match my tablescape, but multi glitter or white would also be fun! Scotch® Expressions are versatile, functional and fun to craft with!
Step 3: Add a votive or tea light candle inside of the jar and place on your Thanksgiving table!
Step 4: Keep the Scotch® Expressions Glitter Tape handy, we'll be embellishing some pumpkins! Add long strips of tape to the pumpkin, from the top to the bottom, as shown in the photo below.
Step 5: To make the glitter confetti pumpkins, use a sponge brush to apply Scotch® Create Multipurpose Glue to the top half of the pumpkins. Scotch® Create has adhesives, from masking tape to spray adhesives, for any project!
Step 6: Quickly, before the glue dried, sprinkle confetti glitter on top. You'll want to go heavier with the glitter on the top and sprinkle less glitter toward the bottom.
Step 7: Decorate different sized pumpkins, using the steps above, and place them on your Thanksgiving table or buffet table. Place the candles around the pumpkins.
What will you make with Scotch® products?
Visit CreateWith3m.com for more Thanksgiving inspiration!


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News02 Jul 2015
Barshim and Bondarenko to meet again in London – IAAF Diamond League
Bogdan Bondarenko at the IAAF Diamond League meeting in London (© Getty Images)
Mutaz Essa Barshim and Bogdan Bondarenko will challenge the high jump world record when they compete at the Sainsbury's Anniversary Games on Friday 24 July, the London leg of the IAAF Diamond League series.
Javier Sotomayor's world record of 2.45m has stood since 1993, but has come under serious threat in recent years as Barshim and Bondarenko have had a series of thrilling clashes. Barshim has beaten Bondarenko nine times compared to eight victories for the Ukrainian and both athletes cleared 2.38m when they last competed on British soil at the 2014 Sainsbury's Birmingham Grand Prix.
This will be their third clash in the Olympic Stadium, their first being at the 2012 Games where both cleared 2.29m with Barshim taking the bronze medal on count-back. One year later, at the Sainsbury's Anniversary Games, Bondarenko gained revenge, jumping 2.38m to comfortably beat his Qatari rival.
World indoor champion Barshim, who is second on the world all-time list with a personal best of 2.43m, has cleared 2.40m or higher on no fewer than eight occasions while world and European champion Bondarenko, equal third all-time with a best of 2.42m, has scaled 2.40m a total of seven times. Both athletes are now confident that the world record could fall in London.
"It was amazing to compete in London at the Olympics in 2012," said Barshim. "To get a bronze medal made it even more special so I can't wait to go back and compete there again at the Sainsbury's Anniversary Games.
"My main focus is to improve myself and with that, the record will fall, and the support from the crowd will play a big role in that."
"Sotomayor's world record is really strong but we're getting closer to it and the Sainsbury's Anniversary Games could be the time when it happens, which would be really special," added Bondarenko. "It's great to be up against someone like Barshim because we push each other further in every competition and it makes the event very exciting for the fans, but there will be a lot of good athletes in London so I will have to be at my very best."
Barshim and Bondarenko headline a strong field, which also includes Britain's Olympic bronze medallist Robbie Grabarz, USA's Olympic silver medallist Erik Kynard and Italy's Marco Fassinotti.
Organisers for the IAAF
2015 IAAF Diamond League calendar
Doha, QAT – 15 May
Shanghai, CHN – 17 May
Eugene, USA – 30 May
Rome, ITA – 4 June
Birmingham, GBR – 7 June
Oslo, NOR – 11 June
New York, USA – 13 June
Paris, FRA – 4 July
Lausanne, SUI – 9 July
Monaco, MON – 17 July
London, GBR – 24-25 July
Stockholm, SWE – 30 July
Zurich, SUI – 3 September
Brussels, BEL – 11 September
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This Workshop Dispatch Officer position is NOW CLOSED. For information on other positions actively being recruited please contact the Youngbrook Recruitment Office on 07 3399 6899 or view available jobs.
With a proud heritage and a long-standing presence in the Brisbane market and best known for its design and manufacturing delivery across stainless, mild steel and aluminium projects, you will have the opportunity to utilise your skills and experience across a role that offers the variety. With a full order book to kick off 2019, on offer, this workshop position is actively being recruited.


When you walk into Parsons House Cypress, you feel like you are at home. A gracious living room, a fireplace, a beautiful backyard and friendly neighbors are just the beginning.
Parsons House offers Assisted Living and Respite Care. The day-to-day, that's what's important to us; making the most of every day comes easier with a smaller community, staff trained in assisting residents with a variety of different diagnoses, and programming that makes everyone excited about today and tomorrow. By knowing our residents and working with their families we are able to provide a proactive approach to care and produce strong resident outcomes.
What's more, Parsons House Cypress is a family-owned community. Being family-owned means there's more personal interest and commitment to delivering the best care possible.
Apr 22 We always enjoy the show when the Friendship Singers perform!


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Q: How to create a macro that takes data from excel and autopopulates it to a word template when a cell takes on a certain value I have an excel workbook that contains columns for name and a decision. If the value of the decision column equals "keep", I want to create a macro that auto-populates the name into a word template that will eventually become a letter mailed to somebody. Here is the table and my code so far:

Name
Decision

John Doe
Keep

Jane Dow
Remove

Sub letter()

Dim rng As Range
Dim row As Range
Dim cell As Range
Dim i As Integer
Set wApp = CreateObject("Word.Application")
wApp.Visible = True

Set wDoc = wApp.Documents.Add(Template:="file name here", NewTemplate:=False, DocumentType:=0)
ActiveSheet.Select
For i = 2 To 3
    If Cells(i, 3) = "Keep" Then

With wDoc
    .Application.Selection.Find.Text = "..name.."
    .Application.Selection.Find.Execute
    .Application.Selection = Cells(i, 1)
    .Application.Selection.EndOf

 ChangeFileOpenDirectory "Directory goes here"
 ActiveDocument.SaveAs2 Filename:="file name here" _
        , FileFormat:=wdFormatXMLDocument, LockComments:=False, Password:="", _
        AddToRecentFiles:=True, WritePassword:="", ReadOnlyRecommended:=False, _
        EmbedTrueTypeFonts:=False, SaveNativePictureFormat:=False, SaveFormsData _
        :=False, SaveAsAOCELetter:=False, CompatibilityMode:=15
End With
End If
Next i
End Sub

The excel workbook looks something like this:
For each row, if the 3rd column value equals "keep", I would like a letter to be generated and saved as "letter_customername.docx", where "customer name" is autopopulated based on the workbook. Additionally, I would like the letter to begin with "Dear 'Customer Name'", where the customer name is again generated from the workbook. What I have as a template is something like this:
Dear ..Name..
Body
Closing
I am envisioning a macro where "..name.." is replaced with the customer name from the workbook.
The code above does not seem to accomplish this. I am stuck and not sure how to proceed. Any assistance would be greatly appreciated!
Note my code is borrowed from here

redpajama_set_name: RedPajamaStackExchange


Rugby is a game with a proud heritage, and is played and enjoyed all over the world. Although it is not as popular as baseball, hockey, football or basketball in America, its popularity is growing all the time and it does definitely have a following here. Watching rugby matches is always fun because they are so action-packed, and betting on them adds even more thrills. Online sportsbooks in American have made this much easier, and as a serious punter you owe it to yourself to investigate mobile betting. Our guidelines below are the perfect place to start.
There are many benefits to online wagers, and one of the best is that you can bet on events all around the world. If you can't find any local or national rugby games to bet on in America, you can be sure that there will be something exciting in the international arena. Look out for big tournaments in Australia, Europe and many other destinations.
Rugby games can be played with the usual full team of fifteen, or with a side of seven. All the major tourneys are played by the fifteen-strong teams, such as the Test Tournament which is the most spectacular rugby event in the world. It kicks off the official season each year with games involving all of the world's greatest rugby nations, and reignites enthusiasm for watching and punting on the matches. There is a separate international circuit for the sevens teams, and watching the different skill sets in each type of game is very interesting. As you get to know their ins and outs more, you may find that you prefer putting wagers down on one kind over the other.
In rugby betting, as with any other kind of betting, one of your most important decisions is who to put money on. We always encourage our readers to do as much research as possible before committing to anything. Find out the ladder, draw and odds of the game you are wagering on, as well as the views of sports commentators in America and the rest of the world. Once you've gathered all of the facts that you can, take some time to listen to your own insights before placing your wagers. You will make better decisions with more confidence if you do.
Once you know who you are supporting, you need to decide what kind of bet to place. The online American-friendly sports betting sites reviewed here offer you quite a few wagering options for rugby games. You can stick to simple bets like single match or tournament winners when starting out, and investigate the more complex and exotic punts as your strategies and confidence grow. Line betting, margin betting and team strategy bets are all waiting to immerse you and you can even bet on the performance of individual players. A great example of this is the Tri-scorer bet, where you put money on who will score the last or first try.
Depending where you are in your punting adventures, rugby bets can be as simple or as complicated as you want them to be. You will be developing the skills you need for the rest of your rugby betting career, and once you start this will be so enjoyable that you'll be glad the journey never ends. Get started now by visiting one of the great online American-friendly sports betting we have reviewed here and putting money on a rugby game or two.


It's easy to let debt get out of control. Aside from your mortgage and car payments, smaller obligations such as credit cards and unpaid bills can pile up—along with their typically high interest rates-to silently rob your savings every month.
One way to get out from under this rubble of uncontrolled liability is debt consolidation. Using the equity in your home to consolidate the other debts in your life can help you organise and eventually eliminate the nagging expenses you've been struggling to cover for years. This works by folding several different types of debt together into your existing mortgage and letting you pay them all down at the much more reasonable interest rate your mortgage lender offers.
Imagine that you owe $250,000 on your home. With a 3-year fixed rate of 4.99 percent, your monthly payments amount to $1,341. If, on top of that, you also owe $15,000 on your car at 10 percent; $20,000 in credit card debt at 18 percent, and another $15,000 in personal debt at 11 percent, just keeping track of all the payments you're making can be a problem. Taken together, these secondary debts amount to monthly payments of $1,644. Added to your mortgage, these expenses push your monthly payments to $2,985.
Folding them all together into your low-interest home loan, however, frees you from the exorbitant fees and demanding repayment schedule associated with short-term debt. In the scenario above, simply adding the $50,000 in other debt to your mortgage raises your home loan payments to $1,609 and eliminates the monthly amount owed on all of your other debts. This one step has thus freed up nearly $1,400 each month to use as you see fit.
It goes without saying that cutting your monthly expenses by half brings tremendous relief all by itself, but there are other advantages to having that extra income every month. Lenders charge interest because money has time value. The sooner you control an amount of money, in other words, the greater the potential rewards. By folding all of your uncontrolled, high-interest debts into your mortgage, you take control of your finances and free up a sizable sum each month for keeping current on your bills, padding your savings account, and investing toward retirement.
Every homeowner's situation is different, and the advantages of debt consolidation depend on your individual debt-to-assets ratio. As with every other aspect of the home mortgage industry, it's always advisable to meet with an experienced broker who is able to guide you through the process, and who will help you understand your options.


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Image of two grain elevators. This slide is part of the Prairie Giants folder, containing both published and unpublished photographs. Prairie Giants was a book produced in collaboration with Brock Silversides about grain elevators in the Prairie Provinces, published by Western Producer Prairie Books in 1986.
Image of a highway passing by two grain elevators. This slide is part of the Prairie Giants folder, containing both published and unpublished photographs. Prairie Giants was a book produced in collaboration with Brock Silversides about grain elevators in the Prairie Provinces, published by Western Producer Prairie Books in 1986.
Hamlin:
Image of two grain elevators and a train. This slide is part of the Prairie Giants folder, containing both published and unpublished photographs. Prairie Giants was a book produced in collaboration with Brock Silversides about grain elevators in the Prairie Provinces, published by Western Producer Prairie Books in 1986.
Image of a grain elevator. This slide is part of the Prairie Giants folder, containing both published and unpublished photographs. Prairie Giants was a book produced in collaboration with Brock Silversides about grain elevators in the Prairie Provinces, published by Western Producer Prairie Books in 1986.
Image of two grain elevators with a freight train passing in between them. This slide is part of the Prairie Giants folder, containing both published and unpublished photographs. Prairie Giants was a book produced in collaboration with Brock Silversides about grain elevators in the Prairie Provinces, published by Western Producer Prairie Books in 1986.
Image of a highway running past two grain elevators. This slide is part of the Prairie Giants folder, containing both published and unpublished photographs. Prairie Giants was a book produced in collaboration with Brock Silversides about grain elevators in the Prairie Provinces, published by Western Producer Prairie Books in 1986.
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