The Grimisuat bisse takes its water from the Sionne. In the heights of Grimisuat, this bisse separates into two, both branches ending in Revouire lake. It is fed from two other sources: the Ayent bisse from which it receives 2/7th of its water and the Prabé tunnel (Savièse bisse). At the start of its course, it intersects with the Sion bisse. .
From the tennis courts, above the village of Arbaz, take the forest road to the left, in the direction of Planeige. The bisse starts under the Sionne bridge. Steps take you up to the path that follows the bisse to above Grimisuat. By road, you can get to the Revouire Lake then the Coop supermarket in the village of Grimisuat. (post bus stop).


text:
Venio Losert (ur. 25 lipca 1976 w Zavidovići) – chorwacki piłkarz ręczny pochodzący z Bośni, wielokrotny reprezentant Chorwacji, dwukrotny złoty medalista olimpijski: igrzysk olimpijskich w Atlancie i w Atenach. Gra na pozycji bramkarza. W 2009 roku wywalczył srebrny medal mistrzostw świata rozgrywanych w Chorwacji.

W sezonie 2012/13 miał występować w duńskim KIF Kolding, ale 30 października 2012 podpisał kontrakt z Vive Targami Kielce.

W 2012 r. został wybrany chorążym reprezentacji Chorwacji na igrzyska olimpijskie w Londynie.

Sukcesy

reprezentacyjne
Igrzyska Olimpijskie:
  1996, 2004
Mistrzostwa Świata:
  2003
  1995, 2005, 2009
Mistrzostwa Europy:
  2008
  2012

klubowe
Mistrzostwa Chorwacji:
  1993, 1994, 1995, 1996, 1997, 1998, 1999
Puchar Chorwacji:
  1993, 1994, 1995, 1996, 1997, 1998, 1999
Mistrzostwa Hiszpanii:
  2005, 2006
  2008, 2009
Puchar Króla:
  2007, 2009
Superpuchar Hiszpanii:
  2007, 2008, 2009
Mistrzostwa Polski:
  2013
Puchar Polski:
  2013
Liga Mistrzów:
  2013

Przypisy

Chorwaccy medaliści olimpijscy
Medaliści Letnich Igrzysk Olimpijskich 1996
Medaliści Letnich Igrzysk Olimpijskich 2004
Piłkarze ręczni FC Barcelona
Piłkarze ręczni RK Zagrzeb
Piłkarze ręczni BM Granollers
Piłkarze ręczni CB Ademar León
Piłkarze ręczni SDC San Antonio
Piłkarze ręczni Vive Kielce
Reprezentanci Chorwacji w piłce ręcznej
Urodzeni w 1976
Ludzie urodzeni w Zavidovići

redpajama_set_name: RedPajamaWikipedia


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Post-Brexit: UK and Other European Returns Look Ugly while US Listed Equity REITs Come Out Looking Great
Brad Case
The continued fallout from the UK's vote to exit the European Union has punished investors with exposure not only in that country but in the rest of Europe too. No assets have been hit harder than British real estate, but investors in the British stock market, European stocks, and European real estate have suffered as well. The chart below compares returns for listed stocks and listed real estate (including exchange-traded equity REITs) in the U.S., the U.K., Europe other than the UK, and the Asia-Pacific region over the days since the Brexit vote.
Listed real estate in the UK was the hardest hit, with total returns plummeting a stunning -31% in the first two trading days following the vote. (In fact, US investors in the UK real estate market would have been hit even harder given that the chart shows losses in local currency while the British pound declined sharply against the U.S. dollar.) Even with a partial recovery, as of July 15th investments in UK listed real estate were still at -22%. Of course, investors in listed UK real estate fared much better than those in funds owning illiquid British property, seven of which refused when investors sought to redeem what were supposed to be liquid shares at the inflated values that managers continued to report.
The broad UK stock market also suffered severely, losing -17% in total returns over the first two trading days; after a partial recovery, UK stock investors have lost "only" -8% of their wealth compared to where they stood just 22 days earlier.
In the rest of Europe, stock investors lost more than real estate investors as the Brexit vote engendered well-founded concerns about the continent's macroeconomic prospects. Europe ex-UK stocks lost -12% in total returns over the initial two trading days, and as of July 15th were still down -3.8%. Europe ex-UK investors in listed real estate did slightly better, losing "only" 8.1% over the first two trading days, and remained poorer by "just" -1.6% twenty-two days after the vote.
Outside of Europe the situation was not nearly so dire, especially for investors in listed real estate. Investors in Asia/Pacific stock markets saw their total returns decline by -3.7% in the first day after the Brexit vote but by July 12th had fully recovered and are now wealthier by +3.0% compared to June 23rd. Listed property companies in the Asia/Pacific region did even better, losing just -2.3% on June 24th and recovering to a gain of +4.2% as of July 15th.
U.S. stock investors, too, have fully recovered after an initial loss of -5.6% in the first two trading days after Brexit (and a huge spike in market volatility, which more than doubled as I noted in another market commentary). As of July 15th, total returns for the broad U.S. stock market were up +2.4% relative to voting day.
The big winners have been investors in exchange-traded Equity REITs in the U.S. The immediate post-Brexit response was less pronounced than in any of the other seven markets mentioned, with a decline of -1.2% over the first two trading days; since then, however, U.S. equity REITs have gained +6.8%. As a result, investors in listed U.S. real estate now have +5.5% more wealth than they did when the Brexit vote happened just 22 days ago—and 27% more than their counterparts in the UK.
The over-riding reason to be invested in the U.S. real estate market through exchange-traded U.S. equity REITs is not to protect against anything as specific as Brexit. Rather, the reason to have a meaningfully diversified investment portfolio with significant exposure to U.S. listed real estate alongside U.S. and non-U.S. stocks, bonds, and cash (for immediate liquidity), is because unexpected events happen all the time, but asset classes—real estate, stocks, bonds, and cash—respond differently to them. In this case, geographic diversification helped mitigate the effects of exposure to the UK while asset-class diversification helped further insulate investors from the fallout of developments in an overseas market. Becoming +5.2% richer over three weeks was simply a bonus.
Technical details: total returns were measured using the FTSE NAREIT All Equity REITs Index (US listed real estate), FTSE Russell 3000 Index (US stocks), FTSE EPRA/NAREIT UK Index (UK listed real estate), FTSE All-Share Index (UK stocks), FTSE EPRA/NAREIT Developed Europe ex-UK Index (Europe xUK listed real estate), FTSE World Europe ex-UK Index (Europe xUK stocks), FTSE EPRA/NAREIT Developed Asia Index (Asia listed real estate), and FTSE All-World Asia Pacific Index (Asia-Pacific stocks).
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redpajama_set_name: RedPajamaCommonCrawl


Olivas Pool Reodeling is open Monday through Friday 8 AM to 5 PM and are available by phone or email. Call us today to set up an inspection, consultation or free estimate. We service Ventura County to the Greater Los Angeles Area, no job is to big or small.


text:
We collaborated with the Canadian Space Agency to help recruit future astronauts!
The Canadian Space Agency (CSA) launched the Junior Astronauts campaign for teachers, educators, youth group leaders and young Canadians in grades 6 to 9. Junior Astronauts is a campaign that allows young Canadians to test their skills and knowledge, to understand the role they can play in future Canadian missions to the Moon, and to get excited about science and space.
Junior Astronauts Streams and activities
They reflect the kind of skills and knowledge that is required from astronauts. These streams were also chosen to appeal to young Canadians with varying interests and to get them excited about space and science.
Learn more about space and science with these fun activities, crafts and experiments for kids.


Washington, D.C. – Ahead of Secretary of Energy Rick Perry's testimony on the Department of Energy (DOE) budget in the Appropriations Committee today, Colorado U.S. Senator Michael Bennet outlined the importance of increasing federal investment in clean energy innovation.
Bennet delivered remarks yesterday at the Advanced Research Projects Agency-Energy (ARPA-E) Energy Innovation Summit, an annual conference and technology showcase that brings together experts to think about America's energy challenges in new and innovative ways. President Trump's budget proposal would eliminate the ARPA-E program, which has a history of success in supporting early-stage clean energy innovation at universities and businesses in Colorado and across the country.
"Despite the administration's budget, we've been assured from the Department of Energy that the Secretary fully supports this program," Bennet said.
In his remarks, Bennet outlined three key efforts to develop the United States as a global energy leader: 1) increase—rather than decrease— investments in ARPA-E; 2) provide more reliable and predictable government funding over the long-term; and 3) work with innovators to convince policy makers of the benefits of investment.
"This month, there will be science fairs in schools across Colorado. If we do our job, we can ensure that, when those kids graduate from college, ARPA-E not only exists but continues to thrive," Bennet said.
A copy of Bennet's remarks as prepared for delivery is available HERE.
PHOTOS from the ARPA-E Summit are available HERE. A brief VIDEO of Bennet speaking is available HERE.


The house at 37 Westall Street includes four bedrooms, three bathrooms and two parking spaces. Stephanie Williams and John Williams of Harcourts Williams real estate are taking expressions of interest until Wednesday, April 10, at 2pm. Click here to find out more.


Kiran Kumar Reddy was the last Chief Minister of united Andhra Pradesh state and he could manage to plunge into that position unexpectedly. As long as Kiran Kumar Reddy was in this position, he was suffocated with Telangana and Jai Andhra Pradesh movements, but KKR supported united Andhra Pradesh. It was said that KKR even put his version strongly infront of Congress high command and took the rebellion path during bifurcation. Kiran Kumar is a native of Chittoor district, but Nellore people also have a soft corner on him, as he is their son-in-law.


Rivera, Diego. "Carta a Fernando Ocaranza." In Textos de arte, compiled by Xavier Moyssén, 222-223. Mexico City: UNAM-IIE, 1996.
Bertram Wolf, Diego Rivera's biographer, states that the period from the late 1930s through the early 1940s was a solitary, confusing time for the painter due to the fact that his name was appearing constantly in newspaper headlines as the protagonist of a battle with the magnate Nelson Rockefeller in New York. When he returned to Mexico, his mystique had died down as a result of the overexposure, and it seems that job offers were scarce—so much, in fact, that by the mid 1930s, he was asked to paint a mural for the staircase of the Antigua Escuela de Medicina [Old Medical School] of the building that had once housed the Oficio de la Santa Inquisición [See of the Holy Inquisition]. As is made evident in the letter in question, Rivera accepted the offer because it was for the Medical School and began by sketching fragments of an outline that was never finished, as may be deduced from the letter sent to Dr. Ocaranza. The initial sketches of this outline are admirable. However, on May 11, 1935, Rivera wrote to Ocaranza—who at the time was the president of the Universidad Nacional Autónoma de México (UNAM), and apologetically explained that he would be unable to continue painting the mural due to illness. In his place, Rivera suggested José Clemente Orozco to carry out the work.
In 1854, the Antigua Escuela de Medicina [Old Medical School] settled into the 16th-century building originally built to house the See of the Holy Inquisition. Some of the greatest figures in medicine of 19th-century Mexico passed through this building, and Mexico's first Museo de Medicina [Medical Museum] was established here. Around 1935, Dr. Fernando Ocaranza, the president of the UNAM, asked Diego Rivera (1886–1957) to paint the central mural on the landing of the staircase leading to the building's second floor. By that time, Rivera had already painted murals for institutions related to health and medicine, such as those he undertook for the Departamento de Salubridad Pública [Public Health Department] in 1929.


Smith, N. J. H. (1981). Caimans, capybaras, otters, manatees, and man in Amazonia. Biological Conservation. 19, 177-187.
Amazonia, the world´s largest tropical rain forest, is often assumed to be a virtually untouched wilderness. The region is often referred to as a demographic void; there is on average only about one person per sq. km. Yet in response to international market forces, the hand of man has penetrated deep into the imposing forests. Since colonial times, wildlife, particularly along rivers, has been exploited on a large scale for commercial purposes. This paper focuses on the effects of the trade on some aquatic animals.


text:
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Home » General » Conflict in Caledonia: Peacekeepers or a new settler militia?
Conflict in Caledonia: Peacekeepers or a new settler militia?
by Krystalline Kraus July 8, 2009 September 9, 2022
The area surrounding the town of Caledonia, Ontario, has become ground-zero when it comes to First Nations land claim issues.
The area surrounding the town of Caledonia, Ontario, has been this province's ground-zero when it comes to First Nations land claim issues.
A 200-year land claim dispute between the government and the Six Nations came to the mainstream media's attention in the winter of 2006, when Six Nations protesters occupied the Douglass Creek Estates (a residential development) to defend their rights to the land.
Six Nations protesters argue that the Douglas Creek site was given to them by the Crown in 1784. Anti-Six Nations protesters from the Caledonia area assert that the land was official surrendered to the Crown in 1841.
Animosity against the Ontario Provincial Police (OPP), under Commissioner Julian Fantino, has come from both sides in the dispute. Residents of Caledonia organized through the group Caledonia Wake Up Call (CWUP) feel that Commissioner Fantino botched the police operation to remove the Six Nations protesters from the development site, triggering clashes between activists and local residents and solidarity blockades.
On June 16, 2006, the Ontario provincial government eventually purchased the development site and is currently holding it in trust until the land claims dispute can be resolved. In addition, the province pledged $1 million to compensate businesses hit hard by the ongoing dispute, bringing the total to $1.7 million.
On March 29, 2007, Minister Jim Prentice announced efforts to advance negotiations with Six Nations and bring 'peace and stability' to the Caledonia area. The twofold announcement includes $26.4 million toward Ontario's extraordinary costs incurred as a result of the occupation near Caledonia.
In addition, it was promised that the Government of Canada would expand its negotiations mandate to allow more flexibility in moving these historical claims forward. Currently, the land claim negotiations continue at the Lands Side Table. (An explanation from the government regarding its negotiations can be found here.)
The land claim troubles have simmered on through these past three years with no resolution, flaring up from time to time like a fire refusing to burn out until its cause is resolved and leading to 148 charges being laid by the OPP against 61 people.
Along with protests from the Six Nations community which caused an Ontario Judge to suspend land negotiations regarding the Douglas Creek Estates until protesters evacuated the site, a group of Caledonia residents organize a "March for Freedom" in 2006 and 2007 demanding that Commissioner Fantino honour his declaration that, "There is one law for all," and end what organizers consider the unequal distribution of justice and law enforcement which they claim favour Six Nations protesters over Caledonia land owners
The recent erection of a Six Nations smokehouse (small tobacco store) on the private property of a local resident is the new flashpoint in this conflict. It has been the fuel for residents Doug Fleming and Gary McHale, members of Caledonia Wake Up Call (CWUC), to create a local militia to defend what they describe as their land and their "Canadian rights" against "Native lawlessness" and "terrorism."
The CWUC claim that the OPP has not been fair in its policing of the two communities, forcing them to create a militia to take matters into their own hands.
According to Tom Keefer from the CUPE 3903 First Nations Solidarity Working Group (FNSWG), militia organizers such as McHale strictly control the group's message by, "Never being openly racist because he frames everything in terms of not being against Natives but that they are for the rule of law, or that they want equal rights. And he constantly talks about the racist police practices of the OPP and about all this oppression towards the while people in the area."
McHale holds fast to his political line, running as an independent candidate — with a law and order platform — in the last federal election in the Haldimand-Norfolk region on Ontario, where he claims he came in first in the city of Caledonia itself.
Crying 'terrorism' to discredit Native land claims
The CWUC has certainly proven its part in the escalation of the conflict here, as it throws around emotion-laden terms such a 'public safety,' 'lawlessness' and 'terrorism' to maintain a red alert level among the citizens of Caledonia
As an example, a June 11, 2009 post on the CWUC site titled, "Six Nation Women march in support of terrorism," stated, "In another exceptionally pathetic display by police, a group of Six Nations women including extortionist Ruby Montour and Janie Jamieson were among those conducting a highway blockade near Hamilton, Ontario."
Also on the CWUC site is a post declaring First Nations activist Sean Brant a terrorist and including numerous links to 'supporting evidence' — including Brant's involvement with the Ontario Coalition Against Poverty (OCAP) and an anonymous quote from a police officer.
Regarding the issue of smokeshacks and trespassing charges, Tom Keefer explains that Fleming is simply making the Six Nations community a scapegoat. Holding Native people, "responsible for a crime wave in Caledonia; breaking and entering into homes and then running back with the stuff they steal." Of McHale, "he pathologizes Native people as being violent terrorists and the CUPE union as supporting terrorism."
The threat from the Caledonia Militia
Keefer helped organize a CUPE 3903 FNSWG protest on June 23, 2009, against the creation of the militia. Two hundred people attended the counter-protest while the police kept the group from shutting down the meeting.
Keefer himself is on CWUC's terrorist list in his own right for supporting the Six Nations. CUPE is also named, charged with supporting terrorism.
Parkinson, head author of CWUC's website, posted his opinion of CUPE and Keefer, "This is a union after all so I anticipated something different from the usual racist, bigoted, ignorant crowd that gathers in small numbers to protest against law and order in Caledonia. Fortunately I'm not afraid to admit it when I'm wrong and I was very wrong."
Regarding the militia itself, Keefer explains, "According to Fleming, the militia would patrol areas in Caledonia by car and by foot wearing uniforms and communicating with radio equipment. If alerted to an instance of native lawlessness the militia would then use reasonable force to affect a citizen's arrest and would hold the native person until such time as the OPP arrived to take the prisoner to jail."
At the June 23 meeting itself, the group "made a show of stating they were not racist and that they welcome people of all races into their militia, but the fact remains they were still going to be carrying about actions to restore the rule of law."
The "rule of law," according to McHale and Parkinson, is of course the rule of law based on a traditional British system steeped in colonial history towards First Nations communities — this is the institution they seek to protect.
Semantics: When a militia become a 'peacekeeping force'
The militia organizers have since declared that they are not organizing a "militia" but rather a "peacekeeping force." It should be noted that, according to the online version of the Farlax dictionary, a militia is defined as: "An army composed of ordinary citizens rather than professional soldiers." Peacekeeping, on the other hand, is defined as, "Of or relating to the preservation of peace." The former refers to "an army" while the later refers to the "preservation of peace," as a wolf wears sheep's clothing.
In a statement released to the media, Doug Fleming laid out the motives of the newly formed group: "Enough is enough! Due to the ongoing reality that the OPP refuses to enforce the Criminal Code with regards to people's property rights I am forming the Caledonia Militia to ensure that the criminal code is upheld. Hotheads need not apply. We're opposing terrorism, not engaging in it." He ends the statement with the words, "Your community needs you."
The militia/peacekeeping force will keep a sharp focus on the Douglas Creek Estates land, which Fleming states is a "safe-zone for native criminals" because the police refuse to patrol there. The ultimate goal would be to provoke confrontation, forcing the police to act.
OPP Commissioner Fantino warned the militia to reconsider its potential actions. He said, "the days of vigilantism are long gone in this country. That group had better seek good and adequate legal counsel because, if they exercise what they think is their right and their authority, they better be prepared to defend themselves, as we always have, and justify what they do."
Aboriginal Affairs Minister Brad Duguid stated, "We're trying to do everything we can as a government to help bring people together… Efforts such as that — forming a militia — it's a shameful attempt to divide, and that's exactly what people should not be engaging in."
Regarding the issue of Six Nations smokeshacks on the private property of Caledonia residents, the Caledonia farmer, Ernie Palmer, at the center of the controversy over land right use told local news that he is upset that the militia is using his situation as their justification, stating he had already spoken to the operator about an agreement to tear the site down. "The agreement that the natives were going to leave was destroyed by Doug Fleming," Palmer said. "My problem is with Doug Fleming."
A tortured analogy: The 'Native Supremacy Movement'
The protection the peacekeeping force seeks to provide is from what organizers have defined as the "Native Supremacy Movement", their enemy and the raison d'etre behind the urgent need for an escalation in tactics represented by the formation of a militia.
For a glimpse into the mentality of the CWUC, we can look at what Jeff Parkinson wrote in a 2007 Internet communiqué entitled "Red Power – Native Supremacy Movement in Ontarip," which was hosted on the CWUC site:
"The ideology of these people is clear. Hatred for everyone but Natives. The same ideology that fuels White Supremacist groups, Black Supremacist groups, a German Supremacist group that changed the world we live in, and now a Native Supremacy movement. To these people equality is a loathsome idea that can not be allowed to take place and we should all live in a world controlled by them or die."
Another section of the site actually states, "Native Protesters and the KKK share ideology." Here, Parkinson rants: "Natives and KKK look the same because both have masks and wear something to cover their head while using Flags to make it look like they are being patriotic. … Burning Crosses or Tires the message is the same."
To conclude the linking of the KKK to the "Natives," he envokes Martin Luther King Jr., "While Mr. King would hold peaceful marches, the KKK showed they were willing to destroy things and attack people to express their sovereign rights … The Natives have repeatedly proven they share the KKK's view that violence, not peaceful marches, is the means to force your sovereign control over land & people."
One of the vwebsites vilified by the CWUC is the Six Nations Reclamation site. Upon searching for language representative of the supposed "Native Supremacy Movement," no text that the website carried contained the same tone as the Wake Up Call website.
Instead, on the Six Nations Reclamation Site, the group explains their concept of ownerships regarding land: "First and foremost is the concept that we are connected to the land in a spiritual way. The earth is our mother and she provides for our long-term well-being, provided that we continue to honour her and give thanks for what she has provided."
"Second, according to our law, the land is not private property that can be owned by any individual. In our worldview, land is a collective right. It is held in common, for the benefit of all. The land is actually a sacred trust, placed in our care, for the sake of the coming generations … If an individual, family or clan has the exclusive right to use and occupy land, they also have a stewardship responsibility to respect and join in the community's right to protect the land from abuse."
On some level, even the notion of anyone forming a militia in Canada provokes that nervous type of humour that we as Canadians are prone to. Even considering the creation of such a group seems reactionary and hysterical if not outright paranoid. Unfortunately, the Doug Fleming's and Gary McHale's types exist in the world and they are dead serious about their intentions.
Using only the short history of Canada for a moment, considering the case of Dudley George, when land right disputes such as these do erupt the First Nations community ends up on the losing side of the conflict, often paying for the ignorance and paranoia of others with their own lives.
And yet, it is often ancient unresolved issues at the heart of such conflicts. In this case, the troubles of Caledonia are only a symbol of the larger, much uglier issue of unresolved land claims, a symbol of a greater problem across Canada where governments hide behind superficial skirmishes between communities rather than tackle the deeper issue of fairly resolving land claims.
krystalline kraus is a Toronto-based writer.
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Tagged: Indigenous rights, Ontario, Six Nations
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8 brethren from West Wales recently visited the Discoveries Lodge 9409 in The Tivoli Hotel in Lagos on the Algarve. This sojourn, to coincide with a golf trip, included 7 members from Tenby Lodge and 1 member from the Narberth Lodge.
Unbeknown to the West Wales party, a further 2 brethren from Flintshire in North Wales had also arranged to visit the Lodge so the Grand Inspector of Portugal VW Rob Levitt decided he would travel down from Lisbon to greet the visiting contingent from Wales.
In the Temple a number of past masters assisted the usual officers in performing a thoroughly enjoyable 3rd degree ceremony.
Following the ceremony, a 3 course festive banquet was held in the Hotel and under instruction from the Grand Inspector, the Discoveries brethren were dispersed amongst the visitors. Due to the Discoveries brethren coming from countries such as Portugal, Holland, Finland, Germany as well as the UK this led to a most enjoyable evening of international brotherhood and fraternity.
This is the fourth time that the group has visited the Discoveries Lodge with a warm welcome being received on each occasion. As a gesture of appreciation W Bro Simon Toy presented the Worshipful Master with a bottle of Penderyn Welsh Whisky as a donation towards the evening's raffle.
The tour organiser would like to confirm that the standard of golf was such that not one ball was lost over the four days !!


On May 6, 2014 Jan Philip Nickel will participate with a poster presentation at the 17th International Symposium "WATEnergyResources – Water, Energy and Resources" of the European Water Association to present results of his Master's Thesis on "Algae cultivation and co-fermentation: Integration in a municipal wastewater treatment plant".
The symposium with a focus on innovative technologies in the water and energy sector will take place at the IFAT 2014 which is held from May 5 – 9 in Munich. IFAT is the world's leading trade fair for water, sewage, waste and raw materials management.
Meet Jan Philip Nickel at the IFAT 2014 in Munich, Germany, on May 5 – 7, 2014. In order to make an appointment in advance, please do not hesitate to contact us.


The Hudson River separates New York from New Jersey, but they are both still connected to it. For most women there is a "valley" of sadness surrounding being with a married person. Most women don't want to share a man, they want their own man! But somehow, so many of us get caught up making the excuse, "but he's separated," and believing all the stories (read: lies) about how horrible his wife is.
Ladies, trust me, I speak from experience. When a man tells you he is separated, tell him to take a hike off the George Washington Bridge. He is a CODE RED FLAG up until the day he files for divorce (or preferably until the day it's official because I've heard some horror stories about spouses who refuse to let go).
There are obvious reasons why married men, and by definition separated men, are Code Red Flags including being disloyal, liars, selfish–just to name a few. Still yet, many women fall into the trap, some unknowingly, others with full and complete knowledge. This is because Mr. Hudson River Valley has perfected the game. He knows women, what we want to see, what we want to hear. He's already gotten a woman to choose to be with him until death should they part.
For one who does not respect his wife, marriage, God, or family, it becomes a game to see how many women he can persuade to choose him. The more he gets chosen, the more he proclaims how good of a man he is. But his perception of what it means to be a good man doesn't fit the definition.
Never confuse a good man with a man who would step out on his wife for a quick thrill with you. And please be sure, 9 times out of 10 that is all you will be to a married man: a temporary fix to fill whichever void he believes his wife is lacking.
After graduating from law school, my sister took me to Jamaica as a graduation gift. While there, I met a man who happened to be from my home state. He told my sister and me about how he was divorced and how his wife took everything. We listened compassionately as he bought us drinks. When he got up to leave, he gave me his contact information.
Although I initially had no intention of calling him, I allowed boredom to overtake my better judgment. Surprisingly, our conversations were great. That is until the day I decided to ask him about his relationship status and he replied, "I'm getting a divorce." Insert Confused Face Emoticon and scream it out with me ladies: FLAG ON THE PLAY!!!
Not only was this man still married but he was also a liar. Any wise woman would surely cut her losses and chuck up the deuces at that point, right? Instead, I allowed this man to talk me into believing this was okay. He introduced me to his family, gave me the key to his home, asked me to move in, and so on.
I tried to be comfortable with this situation but I couldn't be. It was like my mind and my feelings were in a constant battle. How could I trust him? He was a married man who had lied to me in the beginning and I had fallen for the bait like a sucker. Our relationship ended in a few short months later and, just as he painted his wife to be such a horrible person, in the end so was I.
I've shared my story to let you ladies know that we have all played the fool. Notice I said we have played the fool, not we have been played for a fool. I knew better. My gut told me to not go there. My instincts said not to call. But I didn't trust myself. And that is the root cause of the heartache associated with failed relationships: our tendency to overlook the red flags or make excuses for them.
Throughout this guide, I will provide you with scenarios based on anonymous submissions from the Code Red Flag Community. The following scenarios are about dealing with Mr. Hudson River Valley. Take a moment to notice the red flags that you may come across in the story and write them in the space provided after the scenarios before reading my response.
This past August, Brenda met a man whom she absolutely fell for. James was handsome, had a great personality, and he was a leader in his community. He told her his current situation: he is married and his wife is pregnant. He also said that he does not think the baby is his. He plans on making his wife get a DNA test once she delivers the baby.
After a few months, Brenda and James decide to move in together, and his wife lives in a different state. He does not want to file for divorce until his wife "messes up again." James claims his wife has cheated on him in the past, with different guys.
To make Brenda feel better about their "situationship", James has planned a meeting with his family soon, including his wife, which Brenda expects will be a little weird. Brenda has never been in this situation, but he treats her like she has never been treated before. Sexually, financially, and emotionally, he has done things her ex-husband never did. Brenda feels conflicted and needs advice on what to do, but she is too embarrassed to tell any of her friends about her situation she's gotten herself into. She's afraid they will judge her for living with a married man or call her foolish for believing his stories.
Take a moment and write down the red flags you identified in thhe above scenario.
She did not have the courage to tell the story. You need to find courage to share stories that are embarrassing, or when you believe that you should have known better. This is one of the ways our intuition speaks to us. It makes us feel uncomfortable in situations that aren't meant for us.
She worried about judgment. Many times you will hear people say that "only God can judge them". While it may be true that he is the ultimate judge, others can still judge the situations that we place ourselves in. No matter how much we attempt to tell ourselves that the judgment of others does not matter, it still bothers us when we are seen in a less-than-favorable light. We want to believe that we are good people who would not willingly place ourselves in positions that portray us in a manner other than how we see ourselves. When we worry whether our actions or the situation we have placed ourselves in will reflect badly on our character, that's our instinct recognizing a red flag situation. The solution is to remove yourself from that situation immediately. Bad company corrupts good character. The relationships you enter and remain in are a direct reflection of your character.
She lists surface characteristics like looks while claiming James is a man of character. The reality is she fell for his swag and swag is not character. Men with charisma are not necessarily men with good character. This is not to say that all charismatic men lack good character. But swag or charisma, whichever term you prefer, can also be found in players and pimps. We certainly wouldn't list a player or a pimp on an Esquire list of Men with Good Character. We must look deeper than the surface level. There must be something that initially attracts us to a man, but that initial attraction should be only the prerequisite to gain your attention. As we get to know a man, we need to watch his actions to discern whether or not his character matches his swag. When you notice him falling short in areas that a person of good moral character would be held to, it is time to throw him back. Flag on the play! He is no catch.
I decided to join each of those red flags into one flaming red flag! The fact that he is married ought to be a red flag of its own. When added to reasons he gives to justify his adulterous affair, it becomes a three alarm fire.
This man has abandoned his wife. His pregnant wife. If he claims that the child is not his, then why does he needs a DNA test? The only possible way James could be certain that the child his wife is carrying is not his is (1) if he stopped having sexual relations with her before the child was conceived or (2) he is incapable of having children. If either of those were the case, he would not need a DNA test to prove he is not the father. This was game. Now, is it possible that his wife is indeed a cheater? Yes, anything is possible. But why would Brenda want to involve herself in such a messy situation? James is requesting that she be his mistress, his side-chick, until he decides to divorce the woman he vowed to love until death. Think about that. Flag on the Play. He is no catch.
James speaks badly about his wife to Brenda. You may have heard the saying; those who will talk bad about others to you will also talk bad about you. When a man talks bad about a woman to his new love interest, what do you think his intent is? Nine times out of ten it's to make the new woman sympathize with him, to make her believe that the woman is to blame for the failure of his prior relationship, or, in this case, his current marriage. No relationship is without its issues; the red flag lies in not taking personal responsibility for his part in the demise. Instead, he plays the victim and plays on the new woman's nurturing instinct. Some women love to believe that they can fix a man's broken heart by loving him and showing him how she is different from the woman who caused his pain. Men know this–and players use it to their advantage. If and when your relationship with such a man gets rocky or ends, the same way he spoke badly about that woman he will surely speak about you. Flag on the play. No catch!
Married men who cheat on their wives have a predatory instinct allowing them to scope out vulnerable women to prey on from miles away. Such men often look for someone who is in a weakened state because that person is more likely to accept just about any story they are told. Take note that Brenda feels that he does everything that her ex-husband did not do for her. She is treated like "gold" but there is no ring (actually there is a ring; his wife is wearing it). If James was truly interested in being with Brenda, and cared that much for her, he would divorce his wife. He would have not even approached her for an intimate relationship until the divorce paperwork was filed and he had a legal court document bringing complete closure to his marriage. Brenda probably told him about all of the things that her ex-husband did not do, so he does exactly what she says her ex was lacking to keep her comfortable in this illicit affair.
There are two sides to every story, and the fact that James told her things about his marriage and that she would meet his family soon does not mean that either has or will eventually happen. Regardless, why should she care about meeting the spouse and family when legally the wife still gets everything he has if he were to die. If that child is his, James will discover quickly that it is cheaper to keep his wife and he will likely attempt to make the marriage work for the child.
Amy is madly in love with Brandon, a married man, and has been in a relationship with him for eight years. She knew he was married from the beginning but she felt like there was just something special about him. She says he has treated her like a queen. She never has to ask or want for anything, because he is a great provider. Recently, his wife of 20 years found out about their relationship and threatened divorce. Brandon immediately ended his affair with Amy and is trying to save his marriage. Amy is distraught and depressed. She wonders how Brandon can profess his love for her for almost a decade and drop her so easily like she never meant anything to him.
What red flags did you identify in the above scenario?
Signing up to be a side chick, mistress, other woman or whatever you want to call it is never wise. Though there are some men who leave their wife and marry their former lover that is the exception, not the rule! Amy thought that her years in would make her an exception. In love there are no guarantees, especially when you're a willing member of a love triangle.
Amy carried on an illicit love affair with a man who was being deceitful to the woman he vowed to love, honor, and cherish for the rest of his life, but somehow thought the throne belonged to her. She tricked herself into believing she was being treated as a queen when she was nothing more than a paramour. The things he bought her in exchange for her honor were nothing more than frivolous material items he could quickly walk away from, unlike the life he made with his wife.
Amy is confused about what love is. Brandon carrying on an 8 year affair with her is not about love. His cheating on his wife was not love. It was pure unadulterated lust and selfishness. This is the epitome of a man wanting his cake and eating it too. Amy was just as selfish. She attempted to receive blessings and joy from the wife's pain. Now that it has backfired on her, which eventually happens with such affairs, she feels pain and wants to blame him for lying to her for the last eight years. However, she should not ignore the fact that she was a willing participant in this man's web of deceit the entire time.
If a man is willing to cheat on his wife for eight years, why would he not cheat on you if he was to be in a relationship with you? Again, it is cheaper to keep his wife. After twenty years of marriage, his wife may be entitled to half of the marital assets and collect an alimony check monthly.
Infidelity affects children, spouses and the mistress in similar ways. The child of an unfaithful spouse will likely have trust issues when it comes to relationships. They may also experience confusion in regards to identifying real love. They likely will question why a person who supposedly loves them and their mother can be so unfaithful and cause so much pain.
The spouse who was cheated on will likely have a hard time maintaining the current marriage or may be reluctant to start over again. The mistress often begins having trust issues and may suffer from guilt when she tries to move on to a healthier relationship with a man of her own.
Too many women believe that they are the ones who will make a cheater change his game. Those women often end up bitter and are unable to trust a good man if and when they meet one. Don't be that woman. When you meet a married man and he tries to pursue you, cut him short, yell Code Red Flag! FLAG ON THE PLAY! And save yourself from the inevitable heartache.
I hope you have enjoyed this promotional chapter of Flag On the Play.
The book is now available in paperback through Amazon Books and for your Kindle Reader.
This publication is intended to provide authoritative information in regard to the subject matter covered. It is sold with the understanding that the publisher is not engaged in rendering legal, accounting, or other professional advice. If legal or other professional advice is required the services of a competent professional person should be sought.
(c) 2014 Dena Reid, Esq., La. Bella Esq. Publishing, & Code Red Flag. All rights reserved. This book, or parts thereof, may not be reproduced in any manner without the expressed written permission from the publisher; exceptions are made for brief excerpts used in published reviews. Please do not participate in or encourage the piracy of copyrighted material in violation of the author's federally protected rights. Purchase only authorized copies of this publication.
I'm so excited about the release of this book! The writing is easy to follow, and the scenarios are realistic. I look forward to the wisdom and advice you will share. Your experiences are also someone else's. Thank you for sharing.
Great chapter. Your right on point. I wish I had this book 30+ years ago. It would have saved me much heartache. Can't wait to read the whole book.
I enjoyed the excerpt! You definitely broke it down in simple and plain terms. Unfortunately, there are a lot of many women in this situation. They know it's wrong, but once love kicks in, it can be very hard to let go. I pray this book will inspire women to know their worth and wait for God to send them the man of their dreams. Life is too short to waste time on guys who are unavailable, such as married men.
Absolutely fabulous first chapter. Can't wait to see what the rest of the 'men' turn out to be. A very concise, clear picture of the men that women should make 'off limits' in their lives instead of believing themselves to be desperate. We should notice the red flags or be prepared to pay the price for our ignorance later.


Gore and CO2, plutonium "disposal"
Subject: Gore and CO2, plutonium "disposal"
>"Gore has been fighting to reduce CO2 a lot."
that somewhere, but can't find the source.
will give off energy in a reactor if you fission it.


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Q: Optimal way to add small lists to Pandas DataFrame I'm parsing some logs that contain HTTP transactions into  a Pandas DataFrame. Each row is one trasaction, so one column has the IP address, the other has the hostname, etc. For each row (log entry) I'd like to extract the header parameters into a list, and store that list with the rest of the info for that row.
The question is: how to store the list of parameters so that it can be easily cross-referenced with the rest of the data from the log?
For the sake of example, imagine I have this dataframe, where a user's list of pets is stored as a string, and we want to parse out the individual animals and store it as a list. The idea is to store the result of parsing the string so that the actual parse routine only has to run once.
# Original Dataframe
User   | PetsString
----------------------
Mary   | 'dog/cat/rat'
John   | 'dog/lizard'

Method 1) I can add a column to the dataframe and store the list in this column.
User   | PetsString    | PetsList
--------------------------------------------
Mary   | 'dog/cat/rat' | ['dog','cat','rat']
John   | 'dog/lizard'  | ['dog','lizard']

Method 2) I can create another dataframe that has the list entries, with a column indicating the position of the log in the original dataframe for corss-referencing. I'd like to avoid this since I assume that iterating over two dataframes simultaneously is slower than iterating over a single large list. E.g.
User    | PetsString
-----------------------
Mary    | 'dog/cat/rat'
John    | 'dog/lizard'

#Separate DataFrame for cross-reference

User  | Pet
-----------------
Mary  | 'dog'
Mary  | 'cat'
Mary  | 'rat'
John  | 'dog'
John  | 'lizard'

Method 3) Someone suggested adding, say, 50 columns to my existing dataframe and storing each list item in one of the columns. I don't expect to have more than 50 header parameters. This seems speed-optimal but has the nasty limitation in the number of columns. E.g.
User    | PetsString     | Pet0    | Pet1     | Pet2
------------------------------------------------------
Mary    | 'dog/cat/rat'  | 'dog'   | 'cat'    | 'rat'
John    | 'dog/lizard'   | 'dog'   | 'lizard' |

I have two questions:
(i) Assuming I need to compute a function that will read a row and all parameters from the corresponding list, which of the three layouts is speed-optimal?
(ii) Which of these is space-optimal? I'm not sure how Pandas works with objects, but I believe that if I use method 1, Pandas will create a column that is as wide as the longest list. Similarly, Method 3 will have to allocate space for a full 'Pet2' column, even if John doesn't have one
I know a lot of these things may be specific to my particular processor, cache size, use-case, etc. but even a general understanding of the tradeoffs would be very useful to me
thanks in advance for your help!

A: The values in the columns of a Pandas DataFrame are stored in homogeneous numpy arrays. Consider the following:
In [95]: pd.DataFrame({'a': ['foo', 'bar/baz']}).a.dtype
Out[95]: dtype('O')

In [96]: pd.DataFrame({'a': [['foo'], ['bar', 'baz']]}).a.dtype
Out[96]: dtype('O')

This shows that:

*

*When you store strings of different lengths, Pandas uses a numpy array of objects (numpy also has string arrays for equally fixed-size strings, but Pandas doesn't use them).

*When you store lists, Pandas also uses a numpy object array.
Based on this, I think that your first option will have good memory and speed performance. Pandas and numpy have an advantage over regular Python data structures, in things like huge numerical sequences, where the Python overhead of a single number object is huge. A Python list of strings is pretty efficient, and a numpy array of (non fixed-size) strings doesn't really have an advantage over it.
In fact, you might consider if Pandas offers any advantages here at all over plain vanilla Python. Why not a dict mapping strings to lists of strings, for example?

redpajama_set_name: RedPajamaStackExchange


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Trump-Kim summit: world scrambles to decipher 'denuclearisation' deal – as it happened
Donald Trump offers Kim Jong-un security guarantees in document signed by the two leaders
Singapore summit: Kim Jong-un says 'world will see major change'
What have Trump and Kim signed? We read between the lines
Moment Kim Jong-un and Donald Trump share historic handshake - video
Tom McCarthy (now), Matthew Weaver and Kate Lyons (earlier)
Tue 12 Jun 2018 16.36 EDT First published on Mon 11 Jun 2018 19.10 EDT
4.33pm EDT 16:33
3.19pm EDT 15:19 Contradictory messaging on fate of military exercises
1.32pm EDT 13:32 Iran warns North Korea not to trust Trump – report
1.30pm EDT 13:30 Warmbier family: 'hopefully something positive'
1.28pm EDT 13:28 Pentagon 'was not surprised' by halt to military drills
1.22pm EDT 13:22 Sanders call summit 'light on substance' but 'positive'
12.29pm EDT 12:29 What Kim won
11.44pm EDT 23:44
According to Korean media, the "working lunch" between Trump and Kim has begun.
Kim and Trump meet in Singapore – in pictures
We have just got through the menu for the working lunch, which Trump and Kim are due to sit down to in about five minutes. That means they'll be eating lunch at 11:30am local time, which seems on the early side, but at least the menu looks delicious.
They will be eating:
Traditional prawn cocktail served with avocado salad
Green mango kerabu with honey lime dressing and fresh octopus
"Oiseon" Korean stuffed cucumber
Beef short rib confit, served with potato dauphinois and steamed broccolini, red wine sauce on the side
Combination of sweet and sour crispy pork and Yangzhou fried rice with homemade XO chilli sauce
"Daegu jorim" soy braised cod fish with radish, Asian vegetables
Dark chocolate tartlet ganache
Häagen-Dazs vanilla ice cream with cherry coulis
Tropezienne
Updated at 3.40am EDT
Benjamin Haas
Today might appear to some to be a case of life imitating art.
North Korea detonates a nuclear bomb, followed swiftly by a meeting between its leader and the US president and the establishment of formal relations.
Although this sounds worryingly close to real life, it is actually the plot of a four-part North Korean movie released in 2012.
The four-part film, The Country I Saw (really a sequel to the 1980s film of that name), follows a Japanese professor who works out the true nature of North Korea's nuclear programme is to force the US into direct talks. The climax shows a dramatic nuclear explosion, forcing the US to send Bill Clinton to meet Kim Jong-il, the late father of the current leader.
Jeffrey Lewis at the Middlebury Institute of International Studies wrote in a blog post that it showed North Korea "has concluded that its survival as a functioning state in the international system is entirely a product of its military capabilities".
In what is perhaps the best quote of the summit so far, pool reporters say that as they walked away together after shaking hands, Kim said to Trump:
Many people in the world will think of this as a form of fantasy from a science fiction movie.
Updated at 11.10pm EDT
The highly anticipated talks between the US president, Donald Trump, and the North Korean leader, Kim Jong-un, have started.
Kim arrived first to the Capella hotel on Sentosa island in Singapore this morning.
Trump and Kim met on the steps of the hotel and shook hands in front of a display of US and North Korean flags. The handshake lasted about 12 seconds, but was relatively benign by Trump standards.
Before going in to their first talk of the day, Trump said he was confident the talks would be a "tremendous success".
Kim said "it has not been easy to get here" and that "the old prejudices and practices worked as obstacles, but we have overcome them and we are here today".
After their one-on-one discussion, Trump and Kim went into a talk with key advisers.
Speaking to the press before this talk, Kim called the summit "a big prelude to peace". "I believe so too," said Trump.
The bilateral meeting is scheduled to finish at 11.30am before Trump and Kim continue talks over a "working lunch".
The South Korean president, Moon Jae-in, has been photographed watching coverage of the summit and smiling.
In a bizarre moment, Dennis Rodman, a retired US basketballer who has struck up a friendship with Kim, appeared on CNN crying as he spoke about the summit.
Elise Hu (@elisewho)
South Korea's president and prime minister together watched a live stream of the summit opening. You can see their reaction on their faces #TrumpKimSummit pic.twitter.com/GPwa0gy3SB
Trump and Kim are locked away for the "expanded bilateral" portion of today's talks, which run until 11.30am local time.
Unlike their first talk of the day, at which just Trump, Kim and their interpreters were present, at this talk the leaders are accompanied by their key advisers. Benjamin Haas and Julian Borger have this handy guide to who is in the room.
Trump-Kim summit: meet the negotiators
We are getting pictures from the expanded bilateral talk now. The leaders are shaking hands again across the table and exchanging greetings.
Their remarks were hard to catch over the noise of cameras, but Trump said the two leaders would "solve a big problem, a big dilemma that until this point has been unable to be solved."
Kim said through an interpreter:
I believe this is a big prelude to peace... There will also be big challenges ahead but I'm willing to do this.
"We will solve it, we will be successful," said Trump. "And I look forward to working on it with you. It will be done."
In the room with Trump is Mike Pompeo, the secretary of state, Trump's national security adviser John Bolton, and John Kelly, the White House chief of staff.
This meeting is scheduled to run for an hour and a half, before Trump and Kim have a working lunch.
Trump and Kim have emerged from their one-on-one talk
Donald Trump and Kim Jong-un have left their one-on-one talk. They emerged from the talks together. Kim was smiling and Trump was chatting to Kim as they waved to press from the balcony of the hotel.
Updated at 9.58pm EDT


The exhibition centre of Santa Cruz brings us the mother of all arts and crafts fairs - where creations from Europe, Africa and South America will be showcased for the public.
The Recinto Ferial is hosting this years Feria Tricontinental de Artesanía which in previous years had attracted over 100,000 visitors and this year hopes to be no different. This year artisans from over 25 countries will be showcasing their handicrafts and there will also be exhibitions and interactive activities.


You can export masters created in a company, in different formats. You can also choose the type of masters to export. Masters exported in XML format can be imported into Tally.ERP 9 using the Import Masters option.
1. Go to Gateway of Tally > Display > List of Accounts .
2. Click E : Export to open the Export Report .
3. Press Backspace to configure the export options.
4. Select the Language .
5. Select the Format .
6. Enter the Export Location .
7. Enter the Output File Name .
8. Select the Type of Masters to be exported.
9. Set the option Include dependent masters? to Yes .
11. Press Enter to export.
The exported file is saved in the location specified.
You may find this topic useful: 'Exporting Masters' Read it at https://help.tallysolutions.com/article/Tally.ERP9/Data_Management/DM_Export_Data_Masters_TE9.htm/?utm_source=email&utm_medium=social&utm_campaign=tallyhelp Bookmark TallyHelp for information about Tally products.


TV night was moved to Tuesday this week to better coincide with other people's football watching (i.e. Arsenal were playing last night, looks like they did well too), and we took advantage of theoretically starting the evening earlier (no karate for J) by watching the hour & a half Time Team programme on Henry VIII's Lost Palaces. Sometimes I find Time Team programmes irritating because they have this gimmick of "omg we've only got n days how're we gonna manage this!!!", often with what seems like a very arbitrary deadline, but this programme had none of that and I think was better for it. The lost palaces are four of the palaces Henry VIII built during his reign, and they also spent a bit of time digging at Hampton Court which still (obviously) exists. They tied the programme together by giving a history of Henry VIII's reign in terms of architectural achievements (rather than dwelling much on the wives & the religion) looking at how he was using these palaces to display his wealth and magnificance as a political statement as well as just because he liked the finer things in life.
They dug up bits of Beaulieu (the first palace he built), showing that it probably was as big as later plans had suggested, and uncovering what looked like part of the nursery wing, this palace having been built around the time of Mary's birth. No digging, but a bit of looking at the area where it was, for the second palace - the one that was half-building half-tent at the Field of Cloth of Gold. Basically that was a summit meeting with the King of France, and Henry VIII and his retinue of thousands set up a very luxurious camp just outside Calais including a 300x300m two storey palace. All to impress the french with Henry's power and wealth for a couple of weeks. The stuff at Hampton Court was looking for the foundations of some towers built in the tilt yard around the time of Edward's birth, and at the bowling lane. The latter of which they found, but it seems to've been 60m long, so raising even more questions about how the Tudors played the game! Whitehall Palace is under the Whitehall district of London (unsurprisingly) so they didn't get to dig, but the original wine cellar is still there under an MoD building so we got to see that. And Nonsuch was dug up in the 1950s, so we had quite a bit of chat about that (including from the chief chap on that dig). Nonsuch was built for Edward as son & heir and the (cgi) reconstructions they showed looked like a fantasy castle.
One of the themes they were drawing out across the programme was how Henry's designs (and often they were his actual designs not those of a hired architect) were influenced by the styles and architectural theories of the Italian Renaissance. And how even after he'd broken the English church from Rome he was still influenced by this, as the focus was mostly on bringing to mind the Roman Empire - lots of stucco figures on the walls of Roman emperors and Roman gods. So the image one was supposed to takeaway was of Henry as a ruler as great as those of old. But with buildings with all the new modern conveniences (like glazed windows, even the palace in the Field of Cloth of Gold had real glass windows), and all the splendour and opulence (and colour) that the King could afford. Another theme was that Hampton Court wasn't his architectural legacy to the present, so much as the great green spaces round his palaces were - which have become the parks of London (and other places), and provide us even in the middle of our cities with green space.
After a break for cheese and biscuits (but not pickled onions, as those were sadly rather out-of-date) we watched the last of the Secrets of Egypt programmes that we had recorded. We didn't manage to record all of them and we watched them out of order, so I think this was 4 of 5 in the original series (maybe?), and was all about Alexander the Great's tomb. Sadly this felt like they'd padded it out to more of a programme than they had information for, and I would've preferred it if they'd filled the space by giving us more background on Alexander (who I know rather little about other than "conquered the known world and died young") rather than long shots of people wandering around Alexandria looking for the place they believed the tomb to be. However, the main thrust of the programme was that Alexander was buried not once, but possibly three times. Initially when Ptolemy brought his body back to Egypt he was buried at Saqqara to emphasise the legitimacy of Alexander's Pharaohship (and thus Ptolemy's) by burying him with the Pharaohs of old. Then he was moved to Alexandria and given some great shrine that no-one knows where it is any more (although we saw three different theories each with a talking head (one of which was Zahi Hawass), at length, more length than I think we had justification for as everyone seemed to clutch at straws to legitimise their own pet idea). And it's possible that after Christianity took hold in the Roman Empire (and other religions were being suppressed including the cult of Alexander) that the body of Alexander was moved again to the Valley of the Golden Mummies and "hidden" there among all the other burials but still venerated by the local people as it had been by Roman Emperors and Ptolemaic Pharaohs in the past.


text:
The Wild Storm (2017-2019)
A troubled woman, barred by her employer from continuing her research, walks miserably through New York City. It takes her a moment to notice that everybody else is looking up. A man has been thrown from the upper floor of the Halo skyscraper.
And that woman-Angela Spica, sick from the transhuman implants she's buried in her own body-is the only person who can save him.
What she doesn't know is that the act of saving that one man will tip over a vast and secret house of cards that encloses the entire world, if not the inner solar system. This is how the Wild Storm begins, and it may destroy covert power structures, secret space programs and even all of human history.
New York Times best-selling writer Warren Ellis (TRANSMETROPOLITAN, RED, THE AUTHORITY) returns to DC to curate Jim Lee's WildStorm world, with this debut issue resetting the WildStorm universe with new iterations of Grifter, Voodoo, the Engineer, Jenny Sparks and others.
comiXology Unlimited8
Collected Editions4
Issues24
The Wild Storm: Michael Cray (2017-2018)
Warren Ellis' critically acclaimed relaunch of THE WILD STORM gets its first solo spinoff series! Michael Cray, professional assassin, has been betrayed by International Operations and has an alien life-form in his head that's either killing him, transforming him, or both. The only thing that can bring sense to his life is for him to do what he does best: kill the wrong people for the righ
Cemetery Beach
From the creators of the acclaimed TREES graphic novels, which are currently being adapted for television, comes something completely different. A professional pathfinder, his only ally a disaffected young murderess, breaks out of a torture cell in pursuit of his worst extraction scenario ever: escaping on foot across a sprawling and secret off-world colony established a hundred years ago and fill
Ten years after they landed. All over the world. And they did nothing, standing on the surface of the Earth like trees, exerting their silent pressure on the world, as if there were no-one here and nothing under foot. Ten years since we learned that there is intelligent life in the universe, but that they did not recognize us as intelligent or alive. Beginning a new science fiction graphic novel b
The Authority: Revolution
The Authority has settled into its role as the governing body of the U.S. But with many unhappy Americans and a powerful foe working behind-the-scenes, can a second American Revolution be far behind? How long can tyranny stand, before heroes will rise up?


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Home Film I, Frankenstein – Trailer, Posters and lowdown
I, Frankenstein – Trailer, Posters and lowdown
Oct 7th, 2013 @ 9:15 pm EDT
Check out the trailer for what is billed not a horror film but as a fantasy action film, I, Frankenstein which is due in theatres in the new year.
In this world, Dr Victor Frankenstein's immortal creation is called Adam "I am not human. I am unlike none other." Of course there is the search for the secret to his immortality. There is also a war raging between the guardian gargoyles and destructive demons…
The creators of Underworld are behind this with a cast that includes Aaron Eckhart, Bill Nighy and Aden Young.
I, Frankenstein – Posters and Image gallery
I, Frankenstein – Poster "Evil" ©2013 Lionsgate
I, Frankenstein – Poster "Good" ©2013 Lionsgate
I, Frankenstein – Poster "Immortal", Adam (Aaron Eckhart) ©2013 Lionsgate
I, Frankenstein – Adam (Aaron Eckhart) ©2013 Lionsgate, photo by Ben King
I, Frankenstein – Adam (Aaron Eckhart) and Terra (Yvonne Strahovski) ©2013 Lionsgate, photo by Ben King
I, Frankenstein – Trailer
httpv://youtu.be/9S18i53qB6k
I, Frankenstein – Official Information
Set in a dystopic present where vigilant gargoyles and ferocious demons rage in a battle for ultimate power, Victor Frankenstein's creation Adam (Aaron Eckhart) finds himself caught in the middle as both sides race to discover the secret to his immortality.
Brought to life by a cast that includes Aaron Eckhart, Bill Nighy, Yvonne Strahovski, Miranda Otto, Jai Courtney, Socratis Otto, Mahesh Jadu, Caitlin Stasey and Aden Young as Victor Frankenstein.
From the creators of the hit supernatural saga, Underworld, comes the action thriller I, Frankenstein, written for the screen and directed by Stuart Beattie based on the graphic novel I, Frankenstein by Kevin Grevioux. Produced by Tom Rosenberg, Gary Lucchesi, Richard Wright, Andrew Mason and Sidney Kimmel
I, Frankenstein – Theatrical release
US, Canada and UK – January 24, 2014
Kevin Grevioux
Mahesh Jadu
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Learn the financing basics. Know how to shop for a home loan that's right for you.
This takes very little time and lets you know the prices that fits your lifestyle.
The last thing you need is to close a deal and realize you bought a house you don't want. Ask yourself what you're looking for in a home, before you shop. Think about size, commute time and necessary repairs.
deposit. Sometimes offers are accepted based on the amount of the deposit.
are included in the sale.


Hassan El Kholaky & Hany Hassan @ Gŭ Lounge - Gŭ Bar, Nile Maxim Boat, Zamalek, Cairo, Egypt.
Gŭ Lounge is up all week days with nothing but oriental parties, and on Sunday, they are getting the sha3by singer, Hassan El Kholaky, the resident belly dancers and DJ Hany Hassan. For more information, call 01220000022.


This weeks meal prep is Crockpot Paleo Turkey Meatballs and Garlic Parmesan Zoodles. This meal is full of flavor and really filling!
I used a recipe from Pinterest to make the meatballs. Link below.
I saw a video on Facebook of the Garlic Parmesan Zoodles and quickly jotted down the steps so I don't have a real recipe for that but I'll share what I did.
1. Zoodle your Zucchini (I use a spiralizer).
2. Add Ghee (clarified butter) and chopped garlic to a pan set on medium and allow Ghee to melt.
3. Add Zoodles to pan and cook for a few minutes before adding the shredded Parmesan, tossing Zoodles to help melt the Parmesan.
4. Add salt, pepper and red pepper flakes to taste.
Here's the problem I had…the Parmesan didn't melt very pretty and was kind of clumpy. I think next time I'll prepare the Zoodles the same way but only add the Parmesan once the Zoodles are done. The kick provided by the red pepper flakes was perfect!
I "plated" the food in my meal prep containers sans tomato sauce and additional Parmesan. I'll only add those two elements when I'm ready to eat, as seen in this photo above.


The Slow Cooker Challenge ran over two months due to my trip to Nova Scotia at the end of May. As usual, I was delighted by the variety of dishes that the 'Challengers' have submitted, something to suit every meal and every mood. Slow Cooking is such a pleasure, especially when you have been out all day and return to the aroma of your whole meal gently bubbling and ready to serve.
A Girl Eats World brings us a simple dish of BBQ Meatballs made with frozen meatballs and ready made sauce, coming together in the Slow Cooker.
A lack of red wine led to Caroline Makes making this Orange inspired version of Beef Bourgignon: Slow Cooker Beef in Orange and a new dish was born!
Over at Indo Global Food, the slow cooker is being put to good use to make Mango Jam, what a great idea!
Camilla at Fab Food for All brings us a delicious Slow Cooked Pulled Lamb with White Wine and Root Vegetables.
Now this is my kind of dessert! Slow Cooker White Chocolate and Lemon Creme Fraiche Icing and Blueberries. A great slow cooker recipe from Baking Queen 74.
Sometimes the simplest recipes are the best and Sarah has come back with a second offering in the shape of these Slow Cooker Jacket or Baked Potatoes, perfect to come home to.
Many thanks to everyone who entered, look out for the July Slow Cooker Challenge which will include a Slow Cooker Cookbook Giveaway.
I've been told that, no matter how I change my hair and whether I am wearing glasses or not, I am always recognisable as soon as I smile, and I do smile most of the time.
1. Connecting with people - this has to be my top happiness action, whether it is with my family or close friends or my 'virtual' friends in the land of social media, I love to write, talk, listen, share and laugh with all sorts of people.
2. Cooking and Baking - not so much the everyday type of 'getting the meal on the table' cooking, more the weekend, take your time, create and have fun type of kitchen activity.
3. Travelling and Exploring - It doesn't matter if it's only a short distance, I love to visit places I haven't been to before, find out about the history and the stories and if there is food involved then it's even better! I really rediscovered my appetite for travel when I recently visited Canada.
4. Back, Neck and Shoulder Massage - I do love to go for a massage, we are both spa junkies and love being pampered.
5. My home - I've always been happy in my home, but I realised just how important it was for me this year when we discovered dry rot, had our home invaded by builders for three months and ceilings, floors and walls were demolished and rebuilt.
What is your top happiness action?
THINK: As Ferris Bueller once said, "Life moves pretty fast. If you don't stop and look around once in a while, you could miss it." So focus on the good stuff. What happened yesterday, what's good about today? And feel the benefits of a little reflection and observation. Miss this at breakfast and you won't have time to catch up during the day.
TALK: The work/life balance can classically kill off family time, but as you wake up this is the time you are most likely to be together as a family group. Don't leave it for 'later' when 'later' inevitably changes shape during the day.
MOVE: Dorset residents might benefit from acres of coastline and countryside all around, but planning something active shouldn't rest on this alone. Think as you chew about whether you're pacing up and down the office when on a call, or actually walking up an escalator. If you plan it before you leave home, you will do it, rather than fall into the fug of routine. And feel good about it.
ENJOY: Quality of life needs some…quality. From a particular coffee smell that beats all others, to ingredients in your food that you can actually savour above the functional, to little moments of pleasure that you can plan into each day. The link again is the planning, the enjoyment factor and the few minutes to work into the day that make everything a little more enjoyable.
I was provided with Dorset Cereals muesli and porridge, I was not paid to write this and all views are my own.
As soon as I knew I was going to Nova Scotia, I wanted to take some Scottish gifts to my hosts. I was delighted when Wee Sweetie agreed to create a very special Scottish 'sweetie' for me. You can read all about Wee Sweetie in my post: Wee Sweetie, homemade sweeties and candies. The result of this request was a delicious Scotch Mist Fudge featuring Auchentoshan Whisky, meringue made by local producer 'Dessert Me' and Scottish Strawberries, totally delicious.
I also contacted some producers of iconic Scottish products, Mackays for their fabulous marmalades and jams. I felt that Mackays Dundee Orange Marmalade was the most representative from the fantastic range of products that Mackays make in traditional ways in their factory just outside Dundee.
I also felt that Haggis just had to be represented and was delighted when Macsween agreed to provide me with some Haggis Bibles to take with me. These little books contain both traditional and modern recipes using haggis.
Finally, I contacted the delightful PRs for OXO Good Grips, not a company with a Scottish heritage but one producing the very best of kitchen gadgets, sure to be appreciated by dedicated foodies. They supplied me with some really useful kitchen magnets that double up as clips, ideal for securing shopping lists and scraps of paper on which you have written recipes.
I'd like to thank Wee Sweetie, Mackays, Macsween's and OXO Good Grips for their support. All the feedback I had from my hosts was positive and I was delighted to be able to give them something in return for the fantastic experience I had in Nova Scotia.
A collection of the foodie products that I have been sent for review, or simply want to share with you this month. It turns they all fit into the category of quick and easy meals, enjoy!
Terra Nostra is, at first glance, a typical restaurant in the centre of St Ginesio, however they also make and sell high quality pasta and I was able try their Truffle Tagliatelle and dried tomatoes Papparedelle. Both were excellent quality pasta, the kind that easily retains a bit of bite and the flavourings in the pasta also adds to the dish. Each pack also contains a sachet of flavoured oil, which has an authentic taste of the herbs or truffle oil as appropriate to the pasta type.
I made a simple seasonal dish of tomatoes slowly roasted in a pan with a little olive oil and garlic, then I added some sliced olives and at the last minute threw in some feta cheese cubes, this was mixed through the cooked Papparedelle al pomodori with the basil oil and made a really delicious and simple supper.
I'm not averse to a ready-meal, I always have a pizza in my freezer. However, I'm not inclined to buy pasta dishes as ready meals as they are so easy to prepare. I was intrigued by the blurb from Charlie Bigham's " the posh ready meal brand especially for twosomes. It's perfect for when you and your other half want to spend some quality time together, without having to sacrifice the taste!" We don't have a Sainsbury's or Waitrose near where we live and Ocado don't deliver to our area, but I managed to find a Sainsbury's on one of my frequent work trips.
I was supposed to try out the new range of 'world' meals but there weren't any of those available in this store, so I took the chance to get the Moussaka and the Meatballs al Forno. Each ready meal feeds two (although I did get the Moussaka to stretch to feed three) and costs £7.00. That's relatively expensive, but they are the best ready meals I have tasted, you could easily have thought they were homemade. Himself was very impressed and enjoyed both dishes.
Finally, let me Smooze you! Summer finally came yesterday and the temperatures reached a high of 24C (this is massive for Scotland) it was time to break out the Smooze Fruit Ices. Smooze is a 100% natural, freeze at home, fruit ice product that is made up of approximately 50% fresh fruit juice and puree and 40% coconut milk. I tried the Smooze Coconut and Pineapple and himself had the Smooze Coconut and Mango. Both were light and fresh and not too sweet, a really pleasant alternative to more traditional ices.
I was sent the pasta, ready meals and fruit ices to review, I was not paid for these reviews and all opinions are my own. I bought the yogurt myself, I just wanted to share my find with you.
I'm entering the Pappardelle with cherry tomatoes, olives and feta for Simple and In Season, the blogger challenge run by Renatka (Ren) Behan.
It also works for Pasta Please, this one is run by Jac at Tinned Tomatoes and is being hosted this month by Sarah at Maison Cupcake - the theme is 'Fasta Pasta' and this dish was certainly on the table in under 30 minutes.
This month's #SpeedySuppers is also hosted by Sarah at Maison Cupcake, this challenge is jointly run by Sarah and Katie at Feeding Boys and a Firefighter. This month it's all about pasta.
You could be forgiven for thinking that I am posting about Scotland, but rather it is 'New Scotland': Nova Scotia. I started my second day in Halifax with a visit to The Citadel Historic site, part of Parks Canada. I arrived just at the Changing of the Guard, which happens every two hours so most visitors are likely to get the chance to see this impressive display.
My tour guide at The Citadel was Craig, who is the 'School Master' for the Citadel, that's him standing in front of the fire in the soldier's quarters. When the Citadel was reconstructed and developed into a visitor attraction, they had to choose one regiment to be represented, there were many to choose from but they decided to feature the 78th Highlanders, hence the kilts and sporrans. It was fascinating to hear about the lives of the soldiers, how they cooked and ate and entertained themselves. The lengths that the Army went to try to keep them at the Citadel rather than visiting the town, including bringing in locally brewed beer which contributed to the fortune of Alexander Keith's Brewery! It seems that no matter what was provided at the fort, it was unable to compete with the attractions of the town!
What impressed me most about the Citadel were the 'soldiers'. When I first arrived I thought they really were soldiers, but in fact, they are students who are recruited for the summer season. They are drilled and trained in soldierly skills and also in the history of the Citadel, so they can take visitors on tours of the site. In addition to the 78th Highlanders, there is an Artillery Regiment, who were learning how to fire the cannon and going over the drill time and again until they become skilled enough to fire the 12 o'clock gun each day. The presence of these student soldiers, and other costumed characters, really brings the Citadel to life and makes it a living museum.
As a fan of Bernard Cornwell's Sharpe stories (I've read all the books), which are based around the same period of history as the Citadel's hey day, I recognised many aspects of the history of Citadel and the lives of the soldiers and was thrilled to see some rapid load and fire with an original rifle from the late 19th Century. It was incredibly loud and you will see from the video clip that it made me jump!
One of the benefits of joining the Army was access to education and the School Room at the Citadel was the place where the soldiers came to learn. Some would have been learning basic reading, writing and arithmetic, but the artillery required a higher level of knowledge including chemistry and geometry to ensure that the canon fire was effective and accurate. My tour ended with a walk around the moat and the revelation of the remarkable star shape of the Citadel, and other impressive design features which along with the strength of its position, made it a fort which was never attacked.
I would certainly recommend any visitor to Halifax to head to the Citadel and find out about the military history which is so much a part of the development of the town of Halifax.
This is the second in a series of posts about my trip to Nova Scotia,Read the first part of my Nova Scotia adventure: The Bridge, The Bison and the Four Poster Bed and the next episode in my adventure involves a Food Tour of Halifax, I'm looking forward to re-living it!
been away in Nova Scotia, Canada so am posting a little late. Thanks to Elizabeth for her patience and kindness.
First up is Deon at Food Jam with a puff pastry based 'Cheats Pizza' topped with left over bits and pieces from her fridge, perfect No Waste Food Challenge recipe!
Dear Dom at Belleau Kitchen scavenged around in his fridge and freezer and guess what? He found some chicken thighs! This dish reminds me of the beautiful cottage garden at Belleau, and I'm sure it tasted just as good as it looks.
Matty B is a newish blogger at Matty B Bakes and he has embraced the art of food blogging with a vengeance! There are loads of recipes on his blog already including this "Waste not, want not" Chicken Stock which is his entry for the No Waste Food Challenge.
Helen at Food-Friends-Family brings us a pesto made from spinach from her organic veg box and some bits and pieces in her fridge and store cupboard, to come up with this beautiful green plateful of Spinach Artichoke Pesto and Spaghetti.
Sometimes lunch can be a bit boring, but not at Vohn's Vittles where the provided the ingredients for this Mangetout Blue Cheese and Hazelnut Toastie I don't think I've ever had mangetout on toast before, but it does look very good.
I wasn't the only one to use up bananas for the challenge this month. Anne at Anne's Kitchen used her over ripe banana to make Banana and Chocolate Chip Cookies and they proved to be a big success.
Jane at Onions and Paper was very 'punny' with her 'No Waste' Me-USE-li made by clearing out odds and ends from her baking cupboard. Great idea!
The Gluten-free Alchemist lived up to her name and created this spectacular Tarte au Framboise with an excess of raspberries in the freezer and a couple of lemons that had seen better days from the fridge. I love raspberries and will be coming back to this recipe very soon!
Ness at Jibber Jabber has baked a tasty looking Chocolate Malt Cake which is a super-frugal cake to make, costing only 95p and used up some Ovaltine which was in danger of being thrown out.
Another entry from Helen at Family-Friends-Food, this time a Nutella Bread and Butter Pudding. Looks very tasty.
The ripe banana is definitely the friend of the No Waste Food Challenger. Corina at Searching for Spice used hers to make Oaty Banana Bites small chewy clusters of oats, held together with sticky banana and raisins.
This looks like such a delicious tart, named the Three Allium Smoked Chilli Tart by Choclette at Chocolate Log Blog as it features onions, leeks and garlic as well as the courgettes you can see on top.
Spicy, Quirky, Serendipitous is a blog I haven't come across before, but I like the sound of it! We are back to our best friend THE BANANA, this time made into a pancake with finger millet or ragi flour, great for breakfast or tea time.
Leftover Lamb and Rosemary Patties, these could have been made for me. I often roast lamb and prefer it to pork, rosemary is also my favourite herb, so thanks to Annie at A Working Mum's Cookbook for this lovely recipe.
Thanks to everyone for your amazing entries, head over to Utterly Scrummy for the June No Waste Food Challenge.


text:
Pituitary Adenoma and Pregnancy
Sydney Murphy
History & Pituitary Adenoma Epidemiology
Pituitary adenomas are typically prolactinomas, which are the most frequent cause of elevated prolactin levels. Pituitary adenomas comprise over 85% of pituitary tumors, and 25% to 30% of these are hormonally inactive.1 The incidence of prolactinomas is four times greater in women than in men.2
They are the most frequent pituitary tumors among individuals of childbearing age, yet few studies have addressed what effects pituitary tumors during pregnancy or after have on the patient.3 Additionally, prolactinomas occur in both males and females with the same frequency after age 50, and a prevalence of about 10%, according to recorded autopsy studies.2,1
Pituitary Adenoma Diagnosis & Presentation
The pituitary gland undergoes morphological and physiological changes during pregnancy.
The size of the gland increases during late pregnancy and the first few days after delivery, peaking at up to 12 mm, before gradually regressing to a normal size six months later. This growth is linked to lactotroph hyperplasia, which begins in the first month of pregnancy and is brought on by elevated levels of estradiol (E2), the form of estrogen produced by the ovaries.4
Women with prolactinomas frequently experience infertility due to impairment of the hypothalamic-pituitary-gonadal axis (HPG axis).5 This is due to the direct association between pregnancy and the activation of the maternal HPA axis, which increases adrenocorticotropic hormone (ACTH) and cortisol levels.4
When using formal testing, visual deficits can be found in 5% to 15% of cases and up to 50% of cases. Up to 15% to 30% of people experience some sort of pituitary dysfunction. More than one-third of them are macroadenomas, and of those, about 30% will enlarge noticeably over time. The likelihood of clinically significant growth in small, asymptomatic incidental microadenomas is lower, and they are frequently able to be monitored over time with repeated MRIs.6
In some cases of macroprolactinomas, which are characterized by persistent and accelerated growth or regrowth despite repeated attempts at treatment, medications and sometimes surgery may be necessary to lower the risk of growing pituitary tumors during pregnancy.
Surgery after the second trimester should only be considered if the tumor significantly increases in size despite the use of DA therapy while a person is pregnant.7 The main benefits of surgery are mainly seen in cases of critical visual impairment and/or life-threatening endocrine complications. Surgery can also enable the patient to go through with a pregnancy after pituitary tumor removal.8
Prolactinoma diagnosis is based on clinical and laboratory imaging. The pituitary region is now better visible thanks to advancements in neuroimaging, particularly CT, CT angiography, and particularly magnetic resonance imaging (MRI). Adenomas are being discovered more frequently by chance while evaluating conditions like sinus problems (15%), trauma (19%), and stroke (15%), among others.5
The majority of patients have microprolactinomas, which are <10 mm in diameter, and present with symptoms including galactorrhea and hypogonadism. On the other hand, patients with macroprolactinomas, which are >10 mm in diameter, often present with headaches, visual disturbances, and additional hypopituitarism.9
Surgical indications for a pituitary tumor in pregnancy are uncommon and determined by weighing the expected benefits, particularly for the mother, with the risks associated with anesthesia and surgery. These indications, in the case of prolactinomas, are mainly macroadenomas with a symptomatic tumor volume increase and severe visual defects when dopamine agonists fail or are not tolerated.8 The two most efficient treatment options for prolactinomas that can be used in conjunction are dopamine agonist (DA) medication and transsphenoidal surgery.6
Transsphenoidal surgery is performed via minimally invasive microscopic or endoscopic techniques.6 Based on the literature, surgery is being looked at as a possible better option than medications, but at this point, current guidelines support DAs as a primary therapy.10
In DA-resistant cases, transsphenoidal pituitary surgery is recommended. However, fetal exposure and symptomatic tumor growth are possible risks of DA-induced pregnancies.6 About 5% to 17% of prolactinomas are resistant to DA therapy.7
Pituitary apoplexy within pituitary tumors during pregnancy and after delivery is difficult to diagnose because its symptoms can also be caused by other conditions. Pituitary apoplexy during pregnancy is a potentially life-threatening emergency that requires a high index of suspicion during diagnosis.11
Since headaches can be signs and symptoms of multiple serious conditions, high index of suspicion and low threshold for a neuroimaging investigation of pituitary apoplexy are required. Although pituitary adenomas are rarely part of the differential diagnosis in pregnancies and postpartum headaches, they are when in conjunction with vision loss.11
Pituitary apoplexy is commonly caused by bleeding inside a benign pituitary adenoma. It is an uncommon endocrinological emergency that can happen randomly. However, there are known risk factors in the majority of cases of pituitary apoplexy. These include major surgery, hypertension, coagulopathies, and postpartum hemorrhage.11
Management of Pituitary Adenoma in Pregnancy (Nonpharmacotherapy and pharmacotherapy)
The most frequent functioning pituitary tumor, prolactinoma, is responsible for 30% to 40% of hyperprolactinemic infertility in young individuals of childbearing age.7 It is necessary to manage a pituitary tumor pregnancy because it frequently presents with difficult and morbid symptoms, such as headaches and seizures.12
Despite the prevalence of pituitary tumors, there is a lack of standardization in diagnostic and therapeutic approaches.1 The care team decides on each patient's course of treatment and management of the pituitary tumor pregnancy based on experiential evidence, guidelines for nonpregnant patients, and the patient's values and preferences.
Each of the treatments for pituitary adenomas may involve multimodal therapy, including medications — such as dopamine agonists, surgery, radiation, and chemotherapy — and carry risk to both the parent and the developing fetus.12
Although radiotherapy may also control tumor growth, its efficacy in normalizing levels of prolactin is limited. Only 20% of biochemical remission has been observed after radiosurgery. Alternative treatments, such as clomiphene citrate, gonadotropins, and pulsed GnRH, can induce ovulation and pregnancy without changing prolactin levels. Cabergoline and bromocriptine are both alternative options. Cabergoline is better tolerated and more effective in lowering prolactin levels.7
Pituitary Adenoma Monitoring for Changes or Improvement
Endocrine tests used to determine the appropriate treatment method in women with pituitary adenomas need to be interpreted, taking into account the normal physiological changes that occur during pregnancy.
Throughout the trimesters, hormone replacement therapies may require dose adjustments. The known efficacy and safety data specific to pregnant individuals for each therapeutic option should be considered when using medical therapy for excess pituitary hormone.4
The negative effects and potential risks associated with drug use during pregnancy depend on the gestational age of the fetus and the parent. Pregnancy-related clinical trials are rarely approved because they are risky, expensive, and necessitate strict ethical guidelines and long-term follow-up.13
1. Deutschbein T, Jaursch-Hancke C, Knappe UJ, Saeger W, Flitsch J, Bojunga J, Buchfelder M, Ditzen B, Gerlach R, Gertzen E, Honegger J. First German guideline on diagnostics and therapy of clinically non-functioning pituitary tumors. Experimental and Clinical Endocrinology & Diabetes. 2021 Mar;129(03):250-64. DOI: 10.1055/a-1373-4087
2. Cocks Eschler D, Javanmard P, Cox K, Geer EB. Prolactinoma through the female life cycle. Endocrine. 2018 Jan;59(1):16-29. https://doi.org/10.1007/s12020-017-1438-7
3. Laway BA, Baba MS, Bansiwal SK, Choh NA. Prolactinoma Outcome After Pregnancy and Lactation: A Cohort Study. Indian Journal of Endocrinology and Metabolism. 2021 Nov;25(6):559. 10.4103/ijem.ijem_372_21
4. Luger A, Broersen LH, Biermasz NR, Biller BM, Buchfelder M, Chanson P, Jorgensen JO, Kelestimur F, Llahana S, Maiter D, Mintziori G. ESE Clinical Practice Guideline on functioning and nonfunctioning pituitary adenomas in pregnancy. European journal of endocrinology. 2021 Sep 1;185(3):G1-33. https://doi.org/10.1530/EJE-21-0462
5. Jane JA Jr, Catalino MP, Laws ER Jr. Surgical Treatment of Pituitary Adenomas. South Dartmouth (MA): MDText.com, Inc.; 2022.
6. Glezer A, Bronstein MD. Prolactinomas in pregnancy: considerations before conception and during pregnancy. Pituitary. 2020 Feb;23(1):65-9. https://doi.org/10.1007/s11102-019-01010-5
7. Marques JV, Boguszewski CL. Fertility issues in aggressive pituitary tumors. Reviews in Endocrine and Metabolic Disorders. 2020 Jun;21(2):225-33. https://doi.org/10.1007/s11154-019-09530-y
8. Graillon T, Cuny T, Castinetti F, Courbiere B, Cousin M, Albarel F, Morange I, Bruder N, Brue T, Dufour H. Surgical indications for pituitary tumors during pregnancy: a literature review. Pituitary. 2020 Apr;23(2):189-99. https://doi.org/10.1007/s11102-019-01004-3
9. Glezer A, Jallad RS, Machado MC, Fragoso MC, Bronstein MD. Management of pituitary tumors during pregnancy and lactation. Current Opinion in Endocrine and Metabolic Research. 2018 Aug 1;1:42-50. https://doi.org/10.1016/j.coemr.2018.02.002
10. Chanson P, Maiter D. The epidemiology, diagnosis and treatment of Prolactinomas: The old and the new. Best practice & research Clinical endocrinology & metabolism. 2019;33(2):101290.
11. Pop LG, Ilian A, Georgescu T, Bacalbasa N, Balescu I, Toader OD. Pituitary adenoma apoplexy in pregnancy: Case report and literature review. Experimental and Therapeutic Medicine. 2022 Mar 1;23(3):1-7. https://doi.org/10.3892/etm.2022.11143
12. Eckenstein M, Thomas AA. Benign and malignant tumors of the central nervous system and pregnancy. Handbook of Clinical Neurology. 2020 Jan 1;172:241-58. https://doi.org/10.1016/B978-0-444-64240-0.00014-3
13. Calina D, Docea AO, Golokhvast KS, Sifakis S, Tsatsakis A, Makrigiannakis A. Management of endocrinopathies in pregnancy: a review of current evidence. International Journal of Environmental Research and Public Health. 2019 Mar;16(5):781. https://doi.org/10.3390/ijerph16050781
Sydney Murphy is the Associate Editor of HealthDay Physicians Briefing and a freelance science writer based in New York City. You can follow her on Twitter @SydneyLiz_Murph.
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Aplica cada mañana y noche con pequeños toques suaves en la zona del contorno de los ojos. Mantenlo en lugar fresco.
Aqua (water), cetearyl olivate, sorbitan olivate, Persea gratissima (avocado) oil, Leptospermum mel (manuka honey) extract, glycerin, aqua, sodium levulinate, sodium anisate, Theobroma grandiflorum (cupuacu) butter, stearic acid, betaine, glycerine, jojoba esters, glyceryl stearate citrate, glycerin & Albizia julibrissin (Persian silk) bark extract & darutoside, Simmondsia chinensis (jojoba) oil, cetyl alcohol, glyceryl caprylate, Actinida chinensis (kiwi) fruit seed oil, Retinol (Vitamin A) & caprylic/capric triglyceride, tapioca starch, tocopherol (Vitamin E), galactoarabinan, glycerin, Cyathea cumingii (mamaku) leaf extract, Vitis vinifera (Vinanza® Grape) seed extract, Actinidia deliciosa (Vinanza® Kiwi) extract, Sodium phytate, alcohol, dehydroxanthan gum, Daucus carota (carrot) seed oil, sodium citrate, Helianthus annuus (sunflower) seed oil, Rosmarinus officinalis (rosemary) leaf extract, essential oil fragrance of honey: benzyl alcohol†, benzyl benzoate†, benzyl cinnamate†, cinnamyl alcohol†, coumarin†, farnesol†, geraniol†, isoeugenol†, d-Limonene†, linalool†.