text:
Process paves a road to safe, ethical, and fast drug manufacturing — ScienceDaily
11 months ago Cortez Deacetis
Envisioning an animal-totally free drug supply, researchers have — for the initial time — reprogrammed a prevalent bacterium to make a designer polysaccharide molecule employed in pharmaceuticals and nutraceuticals. Released now in Character Communications, the scientists modified E. coli to generate chondroitin sulfate, a drug most effective acknowledged as a dietary nutritional supplement to handle arthritis that is at present sourced from cow trachea.
Genetically engineered E. coli is used to make a lengthy record of medicinal proteins, but it took yrs to coax the microorganisms into producing even the easiest in this class of linked sugar molecules — called sulfated glycosaminoglycans — that are frequently employed as medicine and nutraceuticals..
"It is really a obstacle to engineer E. coli to deliver these molecules, and we had to make several modifications and equilibrium all those changes so that the bacteria will expand nicely," said Mattheos Koffas, lead researcher and a professor of chemical and biological engineering at Rensselaer Polytechnic Institute. "But this function exhibits that it is possible to deliver these polysaccharides making use of E. coli in animal-totally free trend, and the course of action can be extended to create other sulfated glycosaminoglycans."
At Rensselaer, Koffas labored with Jonathan Dordick a fellow professor of chemical and biological engineering, and Robert Linhardt a professor of chemistry and chemical biology. All a few are users of the Centre for Biotechnology and Interdisciplinary Reports. Dordick is a pioneer in utilizing enzymes for content synthesis and creating biomolecular resources for the advancement of greater prescription drugs. Linhardt is a glycans professional and just one of the world's foremost authorities on the blood-thinner heparin, a sulfated glycosaminoglycans presently derived from pig intestine.
Linhardt, who formulated the initial synthetic version of heparin, claimed engineering E. coli to make the drug has lots of positive aspects more than the recent extractive system or even a chemoenzymatic system.
"If we get ready chondroitin sulfate chemoenzymatically, and we make a single gram, and it will take a thirty day period to make, and another person phone calls us and says, 'Well, now I require 10 grams,' we're heading to have to devote one more thirty day period to make 10 grams," Linhardt stated. "Whereas, with the fermentation, you throw the engineered organism in a flask, and you have the materials, whether or not it can be one gram, or 10 grams, or a kilogram. This is the future."
"The skill to endow a simple bacterium with a biosynthetic pathway only uncovered in animals is crucial for synthesis at commercially appropriate scales. Just as vital is that the elaborate medicinal merchandise that we generated in E. coli is structurally the same as that made use of as the nutritional nutritional supplement." explained Dordick.
Koffas outlined 3 important steps the team experienced to make into the microorganisms so that it would generate chondroitin sulfate: introducing a gene cluster to deliver an unsulfated polysaccharide precursor molecule, engineering the germs to make an enough offer of an energetically pricey sulfur donor molecule, and introducing a sulfur transferase enzyme to put the sulfur donor molecule onto the unsulfated polysaccharide precursor molecule.
Introducing a performing sulfotransferase enzyme posed a notably tricky obstacle.
"The sulfotransferases are created by a great deal additional advanced cells," Koffas stated. "When you just take them out of a elaborate eukaryotic cell and set them into E. coli, they're not practical at all. You basically get absolutely nothing. So we had to do quite a bit of protein engineering to make it operate."
The team 1st manufactured a framework of the enzyme, and then utilised an algorithm to aid establish mutations they could make to the enzyme to generate a stable model that would perform in E. coli.
Even though the modified E. coli make a rather modest yield — on the purchase of micrograms for every liter — they thrive underneath ordinary lab circumstances, supplying a robust evidence of strategy.
"This function is a milestone in engineering and producing of biologics and it opens new avenues in numerous fields these types of as therapeutics and regenerative medication that have to have a substantial source of particular molecules whose manufacturing is misplaced with getting old and diseases," claimed Deepak Vashishth, director of the CBIS. "These improvements consider beginning and thrive in interdisciplinary environments built feasible by means of the one of a kind integration of knowledge and sources accessible at the Rensselaer CBIS."
Story Supply:
Components presented by Rensselaer Polytechnic Institute. First prepared by Mary L. Martialay. Take note: Articles may possibly be edited for style and length.
Tags: drug, ethical, Fast, Manufacturing, paves, Process, Road, Safe, ScienceDaily
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23 hours ago Cortez Deacetis


LePaul wrote: I'm not sure I understand the gap you guys are commenting on? A few months when I adjusted it and the new ruby nozzle, everyone said it was perfect?
The gap between the alublock & peek on your photos it's too small. That affects the hot/cold zone making weird stuff like blops or inconsistent printflow. Also, the hole of the fancap it's too big allowing air to hot the alucap.
How do I increase the gap?
Okay I'm looking at the gap you say I should have there.
I did remove the shroud earlier and try to loosen the brass pipe from the heater block. Maybe that requires it to be hot...it wasn't moving.
I did an atomic before removing everything and double checked the extruder feed side looked ok. It's clean.
LePaul wrote: Okay I'm looking at the gap you say I should have there.
My 2 cents if that can help !
2) I could take apart the print head and make the changes shown above. But...I am also concerned about damaging the heater and sensor from the block. If those are damaged, I am unable to print until replacements arrive. Being months behind on printing, I think I am going to try to remove the heater and sensor...and if they come out easily, I can replace with my space block/PEEK and brass coupler. If there's resistance....I may keep things the way they are for now.
Lepaul if you try to take out the sensor/heater the only way to do it it's by hammering the oposite side to push it (specifically because you had some leaks in the past and material will be there). If your prints are ok leave it for now.
- Slower prints, with higher quality.
So yeah, it can work, but some prints will get weird stuff (that probably isn't a problem if you are going to paint the parts layer).
Gr5 50% answer it's to print slower. If you print slower with low aceleration you ofc will get good prints. I'm more focused on printing at no less than 70-50mm/s all the time and getting decently looking prints.
What acceleration setting would you suggest?
I have been using 40mm/sec @ 210 for quite some time now. If I went up to 50mm/sec, should the temp go a bit higher?
Well I can't tell you much because I use 1.75mm and it needs less heat than 2.85. I print 70mm/s at 210-215 for 0.2 layer height. I use standard aceleration 3000 (um2 uses 5000 because his more stable frame and lighter hotend).
To print faster you need to have a perfect hotend assembly so there's less weird preassure changes. But if your prints look ok for now just keep them going until you get free time to adjust everything.
Don't use 210 for 2.85mm filament & 0.2 layer. That's for 1.75mm filament. As I said for 2.85 I don't have the recipe.
True 4000 it's the default. Seems UM2 default it's 3000. Weird, that's what I use on all my machines.
Neotko wrote: Don't use 210 for 2.85mm filament & 0.2 layer. That's for 1.75mm filament. As I said for 2.85 I don't have the recipe.
I wonder what the recipe is!


Getting the kids packed up and ready to go anywhere is a hassle. No matter where we go, we have to give ourselves an extra hour sometimes to get ready. When I told my kids we were going to Patterson Farm Market & Tours, we made it out of the house in under 30 minutes. To say that they were super excited was an understatement.
I usually try and show my kids some pictures of the places we are going to get them excited about going. I went on the Patterson Farms Instagram page and showed them the Pumpkin Princessand a Batman they had made out of hay bails.That was all it took for them to get a hitch in their giddy up to get dressed and in the van.
There literally was something to do for each person in our family. The kids got their face painted, raced rubber duckies, got lost in the corn maize, played in a pit full of corn (seriously) and that was just the first hour. I would highly recommend taking your family there and would highly recommend it to anyone. We loved it so much we might be dropping off the kids at the grandparents for them to take for their Grandparents day and might be going back for their Brewery/Wine day coming soon.


text:
Q: Use Eval with vice versa mode in VBScript Normal usage of Eval function is like:
ValueName2 = Eval("Value" + CStr(CurrentValue) + "Name2")

This can return Value[n]Name2 according to CurrentValue.
Then how I tried to use Eval in vice versa mode:
Eval("Value" + CStr(CurrentValue) + "Name2") = ValueName2

So this can always return ValueName2 no matter if original variable (Eg:Value1Name2,,Value100Name2.....).
But, this time when I check values of Value1Name2, it is empty and VB Script also return an error:

Type mismatch: "Eval"

Then how can I use Eval in vice versa mode?
Thanks in Advance.

A: Eval will always return a value, not a variable reference, so, you can not use Eval to solve the problem.
You can use
Call Execute( "Value" + CStr(CurrentValue) + "Name2 = ValueName2" )

But it is easier and faster to use an array or a dictionary.

redpajama_set_name: RedPajamaStackExchange


Ayurveda, which literally means the science of life (Ayur = Life, Veda = Science), ayurveda is an ancient medical science which was developed in India thousands of years ago. The ancient Vedic literature by sages has clearly laid out instructions to maintain health as well as fighting illness through therapies, massages, herbal medicines, diet control and exercise.
Physical therapy (PT), also known as physiotherapy, is a physical medicine and rehabilitation specialty that, by using mechanical force and movements, remediates impairments and promotes mobility, function, and quality of life through examination, diagnosis, prognosis, and physical intervention.
Myology is the study of the muscular system, including the study of the structure, function and diseases of muscle. The muscular system consists of skeletal muscle, which contracts to move or position parts of the body (e.g., the bones that articulate at joints), smooth and cardiac muscle that propels, expels or controls the flow of fluids and contained substance.
Naturopathy is a system of working towards the cure of diseases without using medicines. It is an ancient and traditional science which integrates the physical, mental, and spiritual aspects of our natural constitution. Naturopathy has the capacity to prevent and in some cases also cure the disease.
Rheumatology is a sub-specialty in internal medicine, devoted to diagnosis and therapy of rheumatic diseases. Rheumatology deal mainly with clinical problems involving joints, soft tissues, autoimmune diseases, vasculitis, and heritable connective tissue disorders. Many of these diseases are now known to be disorders of the immune system.
Hijama (Arabic: حجامة lit. "sucking") is the Arabic term for wet cupping, where blood is drawn by vacuum from a small skin incision for therapeutic purposes. The practice has Greek, Arab, Turkish and Persian origin and is mentioned by Hippocrates.
Speech Therapy deals mainly with the evaluation and treatment of communication disorders, cognition, voice disorders, and swallowing disorders.
There is no one treatment that works for every child with a developmental delay. Children are unique; they learn and grow and develop in their own way, at their own pace, based on their strengths and weaknesses. Any treatment plan will take this uniqueness into account and be designed to focus on individual needs.
Behaviour therapy is a broad term referring to psychotherapy, behaviour analytical, or a combination of the two therapies. In its broadest sense, the methods focus on either just behaviours or in combination with thoughts and feelings that might be causing them.
Internal medicine or general medicine (in Commonwealth nations) is the medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases.


The contact with my fellow scientists and with students, and the intense satisfaction of solving a maths equation, in research as well as when teaching. I still get a kick out of it, and I can't believe it's my actual job.
My main task is to write scientific articles for international journals. It's a long process! I have to come up with an original idea, test it in theory, then test it with computers and experiments. If the idea is original and confirmed by the experiments, I write it as an article which I then submit to a journal who will send it for (anonymous) review to other scientists. If they find it of worthy scientific value, it is then published. It can take years from beginning to end! I also have other scientific responsibilities such as being an editor for several scientific journals, writing grant proposals and administrating the successful ones, mentoring final year Undergraduate students, summer interns, PhD students and postdoctoral fellows, going to conferences to present my work and discover that of others, etc. Beside doing proper science, I also deal with email, paperwork, preparing and delivering lectures, writing and grading exams, visiting schools and taking part in outreach activities such as this one, or FameLab, or Bright Club where I had to develop a stand-up comedy routine (look it up on YouTube)!
Coming up with new scientific ideas all the time. Staying focused for hours, days, months and sometimes years on a problem. Learning and understanding new results and new techniques. Writing the results in a clear manner, that will be understood by the readers. Lecturing to large classes. Facing the general public in outreach activities.
There are two types of days: those with lecturing and those without. In NUI Galway there are two semesters of 12 weeks for lecturing, and during those I teach and do research (and some paperwork) while during the remaining 28 weeks, I'm a full-time scientist. Most of the time it's just me and my paper/computer, calculating and writing. Not so exciting to look at! I'd say I spend 80% of my time at my computer, trying to discover new things or coming up with new ideas. I also collaborate with others (scientists in Ireland and abroad, and my PhD students) and we write scientific articles.
One thing led to another!
First I wanted to be a secondary school teacher in Physics and Chemistry. So I did a BSc in Physics (and had to repeat second year!).
Then I did a HDip in Education (1 year) to become a qualified teacher.
By then I was tired of studying so I took a year off and went to work in Eddie Rockets in Rathmines for a while. It was fun but tiring!
Then I had to do my French National Service and I was sent overseas for two years, in New Caledonia (look it up!).
Then I decided to come back to Ireland for an MSc in Mathematical Physics in UCD.
Finally I became a secondary school teacher in Rennes, France. But after a year I realised I missed the maths too much and went back to UCD for a PhD in Mathematical Physics (3 years).
Then I got a temporary lecturing job in Texas A&M University, USA (two years).
Then a permanent scientist job in Paris, France. I stayed there six years and then got a Fellowship to return to UCD for two years.
I was planning on going back to Paris but applied to the job of Chair of Applied Mathematics at NUI Galway, just to see how it'd go, and I was offered the position! I've been there since 2010.
Proving that brain is softer than jelly!
The administrative part: having to go to meetings, sitting on committees, taking the minutes, writing reports, compiling data, that sort of things. But it has to be done!


Good old Jello is totally trendy again thanks to Victoria Belanger—aka the Jello Mold Mistress of Brooklyn with the book Hello, Jell-O!. This book has totally fun new Jello recipes such as: Pumpkin Pie and Eggnog Rum, but also kid-friendly favorites such as Root Beer Float Squares and more.
We have switched to cloth napkins in our house. The kids are delighted when we make fun folds with them. The book Napkin Origami: 25 Creative and Fun Ideas for Napkin Folding makes it easy. Swans and peacocks will jazz up any dinner table. Pictures and easy directions make it simple!
Making lunch is often a chore. Make it a little more exciting with fun new lunch boxes. EasyLunchboxes 3-compartment Bento Lunch Box Containers are designed with kid-friendly easy-open lids. These fun bento style are microwave and dishwasher safe.
I scream you scream… we all would scream for yummy homemade ice cream! It's not as hard as you think to whip up an ice cream concoction fit for your little prince or princess. Check out these Make Your Own Ice Cream Mugs. Simply place ice cubes and salt into the lower part of the cup, and add fresh ingredients to the kid sized mugs and shake for three minutes to make delicious homemade ice cream.
It is important to keep mommy and daddy caffeinated so that they have enough energy to chase the kids. Might as well do your daily coffee habit in style with the DeLonghi Kmix Drip Coffee Maker. This compact coffee maker is minimalist and comes in eight great colors.


text:
CAM steht als Abkürzung für:

 Caja Mediterráneo, eine spanische Sparkasse
 Cambridgeshire, englische Grafschaft, Chapman-Code
 Canona Antimagnetica, eine Vorrichtung zum vorzeitigen Zünden von Magnetminen
 Carl Amesmaier München, ehemaliger deutscher Automobilhersteller
 Cartoon Art Museum in San Francisco
 Catapult aircraft merchantman, ein Handelsschiff mit Flugzeugkatapult, siehe CAM-Schiff
 Cell adhesion molecule, englisch für Zelladhäsionsmolekül
 Center of Automotive Management
 Central America, Zentralamerika (UNDP-Code)
 Centrifuge Accommodations Module, ein Modul der Internationalen Raumstation
 Centro de Arte Moderna, ein portugiesisches Museum für Moderne Kunst in Lissabon
 China Auto Manufacturers, ein südafrikanischer Automobilhersteller
 Common Access Method, eine Abstraktionsschicht im FreeBSD-Geräteuniversum
 Complementary and alternative medicine, englisch für Komplementär- und Alternativmedizin
 Computer-aided manufacturing, (dt.: rechnerunterstützte Fertigung), bezeichnet die Verwendung einer von der CNC-Maschine unabhängigen Software zur Erstellung des NC-Codes
 Computer-aided mapping in der Kartografie
 Conditional Access Module, ein Entschlüsselungsmodul im Digitalfernsehen
 Confusion Assessment Method, ein Test zum Erkennen eines Delirs
 Constantly awake mode bei Wireless Local Area Network
 Constitutive active mutant, ein ständig aktiver G-Protein-gekoppelter Rezeptor (GPCR)
 Content-addressable memory, (dt.: Assoziativspeicher)
 Content aggregation model in SCORM, ein Referenzmodell für elektronische Lerninhalte
 Contract Air Mail, von Privatunternehmen bediente US-Postflugstrecken
 Crassulacean acid metabolism, englisch für den Crassulaceen-Säurestoffwechsel bei Pflanzen
 Kambodscha nach dem IOC-Code
 Kamerun nach dem Kfz-Nationalitätszeichen
 Common area maintenance charges, umlagefähige Instandhaltungskosten in gewerblichen Mietverhältnissen nach US-amerikanischem Immobilienrecht

CaM steht als Abkürzung für:

 Calmodulin, Protein

Cam steht für:
 Cam-Rip, das illegale Mitschneiden eines Kinofilms mittels eines Camcorders
 Camcorder (in umgangssprachlicher Kurzform)
 Digitalkamera (in umgangssprachlicher Kurzform)
 Webcam (in umgangssprachlicher Kurzform)
 cam, das englische Wort für Kurvenscheibe
 Klemmgerät (engl. camming device), beim Sportklettern

in Geographie, Meteorologie und Astronomie:
 River Cam (Great Ouse), Fluss in England
 tropischer Sturm Cam von 1999
 Camelopardus (lat.), siehe Giraffe (Sternbild) in der Nomenklatur der Fixsterne
 Cam Rock, Rifffelsen im Archipel der Südlichen Orkneyinseln

Cam ist der Familienname folgender Personen:

 Bruce Cam (* 19**), US-amerikanischer Filmproduzent und Filmregisseur
 Diogo Cam († ~1486), portugiesischer Seefahrer und Entdecker, siehe Diogo Cão
 Helen Cam (1885–1968), britische Historikerin
 Cẩm Ly (* 1970), vietnamesische Sängerin
 Philippe Cam, französischer Musiker und DJ

 Pseudonym von Francesco Carotta (* 1946), italienischer Publizist

 Für den türkischen Familiennamen (mit Namensträgern) siehe Çam

Siehe auch:
 Le Cam

Abkürzung

ru:Кулак
uk:Кулак

redpajama_set_name: RedPajamaWikipedia


text:
New Broadband Protocol Turns Routers into IoT Gateways
Greenwave Systems is offering its AXON software, using the User Services Platform (USP) protocol, to provide internet service providers with the ability to sell IoT solutions to their customers, leveraging internet routers.
By Claire Swedberg
Tags: Innovation, Internet of Things, IT/Infrastructure, Security and Access Control, Sensors, Standards and Regulation
Managed networks company Greenwave Systems has begun providing a solution that brings the Internet of Things (IoT) into homes using a new application service protocol from the Broadband Forum. The User Services Platform (USP) serves as a standardized protocol to allow companies to manage, monitor, update and control connected devices, services and home networks. Greenwave's AXON software platform uses the USP, and aims to enable internet service providers (ISPs) to offer applications for home intelligence to their customers (home owners and businesses).
Applications built in compliance with the USP standard could range from lighting and home security to sensor management, using an ISP's router as the gateway to such solutions. Greenwave claims it is the first technology company to provide a USP-based solution. The firm also helped to develop the standard with the Broadband Forum, based on its own solutions, says Tim Spets, Greenwave Systems' senior IoT systems and standards architect. The goal, he explains, is to extend communication beyond simply the router, to a network of sensors or devices that can communicate wirelessly within a home or other building.
Image courtesy of Greenwave Systems
The Broadband Forum is a consortium dedicated to developing broadband network specifications. Its members include service providers, telecommunications companies, and device and equipment manufacturers. Greenwave Systems is a software provider of managed services. Businesses can use its AXON software platform to provide IoT access to end users.
The USP protocol comes more than a decade following the release of an open standard known as TR-069, which enables service providers to communicate with the internet routers they provide to customers for network access. TR-069 allows them to send software updates to routers, and to perform troubleshooting remotely—but that's where their access to the router ends.
Greenwave built its AXON proprietary solution in 2015 so service providers can offer the software application to customers. The solution would allow users to connect the router to sensors or other Wi-Fi based devices via their smartphone or tablet, in order to accomplish such functions as controlling lights using the AXON app. "We have the architecture built that can accomplish this," Spets says. However, he notes, as an open protocol, TR-069 does not provide that level of access to applications for multiple end points, such as sensors, smartphones or other devices, via a router.
That makes home installations limited to custom solutions provided by a variety of vendors. With an open protocol like USP, Spets says, ISPs could begin offering smart-home solutions via apps that enable two-way communication between devices and the router. "We brought a lot of what AXON offers" to the Broadband Forum's efforts, he states, which laid the groundwork for the USP standard's development.
Kerlink Brings LoRaWAN Connectivity to Scotland, Japan
Petrochemical Company Launches Refinery of the Future With IoT
DOD's RFID Efforts Are Winning the War on Inefficiencies
RFID Journal LIVE! Delivers Value, Guaranteed
Still Crazy After All These Years
RFID Journal LIVE! 2018 Report, Part 2
RFID Goes to College
Why Standardization Is Fundamental for the IoT in Brazil
RFID in High Tech 2012 Report

redpajama_set_name: RedPajamaCommonCrawl


Hessiger, H. (1836). Letter, To: Patrick Barry Hayes, From: Howland Hessiger, January 5, 1836.
Hessiger, Howland. Letter, To: Patrick Barry Hayes, From: Howland Hessiger, January 5, 1836. 1836.
"Letter, To: Patrick Barry Hayes, From: Howland Hessiger, January 5, 1836." Series XI Patrick Barry Hayes. Digital Library @ Villanova University. Date Accessed: 22 April 19, 6:11 AM.


text:
Q: The reversibility of the adjoint operator Let $H$ - a Hilbert space, operator $A \in \mathcal{B}$ and $A$ is reversible. How to prove the fact that $(A^*)^{-1} = (A^{-1})^*$?

A: Simply notice
$\langle Ax,y\rangle=\langle x,A^{*}y\rangle=\langle A^{-1}Ax,A^{*}y\rangle=\langle Ax,(A^{-1})^{*}A^{*}y\rangle$.
Thus $(A^{-1})^{*}A^{*}=I\Rightarrow (A^{-1})^{*}=(A^{*})^{-1}$

A: For any $v,w \in H$ you get:
$(v,w) = (T T^{-1}v,w) = (T^{-1}v,T^*w) = (v,(T^{-1})^*T^*w)$,
yielding $(T^{-1})^*T^* = \mathrm{Id}$.

A: Well for any operator $T$, $T^*$ is defined by the equation $(T^*u,v)=(u,Tv)$ for all $u,v$. So, in particular, $(A^{-1})^*$ will be the operator satisfying $((A^{-1})^*u,v)=(u,A^{-1}v).$ Putting $v=Aw$, we have $$(u,w)=((A^{-1})^*u,Aw)=(A^*(A^{-1})^*u,w).$$
Thus $A^*(A^{-1})^*=1$, so $(A^{-1})^*=(A^*)^{-1}.$

A: ziggurism shows that $(A^{-1})^*$ is a right inverse of $A^*$, while Konstantin and Basanta R. Pahari show that it is a left inverse. As the following (well known) example shows, but both of these are needed in an infinite dimensional Hilbert space. Take $H$ to be the Hilbert space of square-summable real sequences. For $x=(x_1,x_2,\ldots)\in H$ define $Lx = (x_2,x_3,\ldots)$ and $Rx:=(0,x_1,x_2,\ldots)$.  Both $L$ and $R$ are bounded linear operators on $H$, $L$ is onto but not one-to-one, while $R$ is one-to-one but not onto. Finally, $LRx =x$ for all $x\in H$. That is, $L$ is a left inverse of $R$. But $RLx=(0,x_2,x_3,\ldots)$ which is not the same as $x$ when $x_1\not=0$.


The journey to a diagnosis of Pompe disease can be long and complicated.
Very often it can involve visiting several different doctors and having to undergo a variety of tests because symptoms can affect many areas of the body, including the muscles, lungs, and heart, and because there are many different types of tests that can be performed. Doctors often need to first rule out other diseases that share similar symptoms with Pompe disease; this is referred to as a differential diagnosis.
The tests above can suggest a diagnosis of LOPD, but only 2 tests can diagnose LOPD definitively: a test for enzyme activity and a genetic test for gene mutation.
The methods listed below can be used to test for GAA enzyme activity. The dried blood spot (DBS) test is commonly used due to its accuracy and convenience.
This figure shows the pattern of inheritance for Pompe disease. Patients with Pompe disease inherit a gene variant from each of their parents. If someone has 1 copy of the altered gene, they will not develop the disease; they are considered a "carrier." Only when a person has 2 copies of the altered gene will the disease occur. This is referred to as autosomal recessive inheritance.
If your doctor thinks it is appropriate, he or she may also order a multigene test panel to investigate the possibility of Pompe and other inherited disorders simultaneously.


text:
NHL, NHLPA agree on protocols to resume season
In this Sunday, Feb. 16, 2020 file photo, Toronto Maple Leafs forward Jason Spezza (19) controls the puck during the second period of the team's NHL hockey game against the Buffalo Sabres in Buffalo, N.Y.(AP Photo/Jeffrey T. Barnes)
By STEPHEN WHYNO
Published: Jul. 5, 2020 at 8:11 PM CDT|Updated: Jul. 5, 2020 at 11:13 PM CDT
(AP) - The NHL and NHL Players' Association agreed Sunday on protocols to resume the season, a major step toward the return of hockey this summer.
Deputy Commissioner Bill Daly told The Associated Press there was an agreement on protocols for training camps and games and the sides are still negotiating an extension of the collective bargaining agreement, which is crucial to the process.
A person with knowledge of the situation said the return-to-play protocols would only go into effect if each side votes to approve the full package of the CBA extension and return-to-play agreement. The person spoke on condition of anonymity because CBA talks are still ongoing.
To complete a return, two-thirds of the league's board of governors and majorities of the players' executive committee and full membership must vote in favor.
If everything is ratified, it will end a pandemic-forced shutdown that began in mid-March. Games would resume in late July or early August with 24 teams taking part in an expanded playoffs, finishing with the Stanley Cup being awarded in October.
The agreement was first reported by TSN.
The 47 pages of protocols outline the health and safety measures the league and players agreed to after several weeks of negotiations. Any player has until 5 p.m. EDT on Tuesday to notify his team if he's choosing to opt out of participating in training camp and games, with an additional deadline expected after ratification of the agreement.
For those playing, each team is limited to 30 skaters and an unlimited amount of goaltenders for camp and total roster of up to 31 players for games. Each team is limited to 52 personnel in its game city, a group that must include two trainers, a doctor and compliance officer in addition players, coaches and management.
They are expected to be quarantined from the general public during play at least for the qualifying and first two traditional playoff rounds. Family members will be permitted to join when play is moved to one city for the conference finals and Stanley Cup Final.
All team and league employees plus hotel, restaurant and arena staff coming in contact with players will be tested daily in the two "hub" cities.
One player's positive coronavirus test result is not expected to shut down play entirely. The league has said it would isolate any player or staff member who tests positive, acknowledging an outbreak would threaten the remainder of the season.
"The players will be pretty well-protected from being exposed," Montreal Canadiens owner Geoff Molson said during a conference call in June. "It's going to be a completely different way for you all and us watching hockey and being around a team because players will be really well protected throughout the process."
The protocols include a provision for Commissioner Gary Bettman in consultation with NHLPA executive director Don Fehr to postpone, delay or cancel games in the event of a COVID-19 outbreak.
Assuming the protocols are approved, teams are expected to open training camps July 13 before traveling to the two hub cities for games. Players have been able to skate and train off-ice in voluntary, small-group workouts since June 8 — nearly three months after hockey was halted March 12 with 189 regular-season games remaining.
Returning for the playoffs is seen as a stirring victory for the NHL, which like other top leagues faced the prospect of losing millions more without the television revenue tied to the postseason. There were deep concerns about canceling the rest of the season and word of positive tests didn't help: 26 players since June 8, in addition to almost a dozen before that.
Boston defenseman Matt Grzelcyk called the positive test results "eye-opening" but expected. A few players expressed concerns in recent weeks about the uncertainty surrounding a return.
"We have obviously a unique situation right now," Montreal goaltender Carey Price said. "The NHL and the NHLPA are trying to make the best of a very difficult situation. Moving forward I'd like to play, but we have a lot of questions that need to be answered and a lot of scenarios that need to be covered."
If the protocols and an CBA extension cover those scenarios for enough owners and players, there will be a path forward to hand out the Stanley Cup. Only twice since 1893 has the Cup not been awarded: in 1919, when the final couldn't be completed because of the Spanish flu pandemic, and 2005 when the season was wiped out by a lockout.
For more AP NHL coverage: https://apnews.com/NHL and https://twitter.com/AP_Sports
Copyright 2020 Associated Press. All rights reserved.


text:
Denver Broncos free safety Justin Simmons becomes first NFL player to get franchise tag in 2021
Nate Davis
The Denver Broncos are playing tag once again.
For the second straight year, the team is franchising star free safety Justin Simmons, who made the Pro Bowl for the first time in 2020.
Simmons, 27, has 12 interceptions and nearly 300 tackles over the past three seasons – a stretch when he has not missed a single game.
He stands to make $13.7 million if he plays on the tag in 2021 but has until July 15 to sign a long-term extension.
"Designating Justin with the franchise tag is a procedural move that allows us to continue working on a long-term deal," new Broncos general manager George Paton said in a statement Friday.
"We are completely focused on making sure Justin remains a big part of the Denver Broncos for many years to come."
A third-round pick out of Boston College in 2016, Pro Football Focus ranked him as the league's eighth-best safety in 2020 – a dip after he came in second overall in 2019.
"Justin is one of our core guys," Paton said Thursday.
FRANCHISE TAG RECOMMENDATIONS:For all 32 NFL teams as two-week window opens
"Our goal since I got here is to sign him to a long-term deal."
Simmons becomes the first player tagged in 2021. NFL teams have until Tuesday at 4 p.m. ET to use the franchise or transition tag to secure one of their pending free agents.
Follow USA TODAY Sports' Nate Davis on Twitter @ByNateDavis.
If you love talking football, we have the perfect spot for you. Join our Facebook Group, The Ruling Off the Field, to engage in friendly debate and conversation with fellow football fans and our NFL insiders. Do the right thing, sign up now!


What's a little less clear is Stan Lee's hand in creating her. Some describe his involvement as a full collaboration between he and Atkinson. Others say his was more of a technical involvement, since he was, at the time, editor-in-chief at Timely Comics.
During the first 20 years of her existence, Millie was quite clearly in a different universe than the the Marvel superheroes. However, with the wedding of Sue and Reed Richards in Fantastic Four Annual #3 (1965), her name came up in casual conversation of some of the wedding guests. Though not actually seen in this issue, the dialogue established her as a famous-enough model to have earned a place at the high-profile wedding. When the wedding was retold by Alex Ross in Marvels, her presence at the wedding was reconfirmed.
Though she did not participate heavily in the events of the Marvel Universe following the Storm-Reed wedding, she has been seen in Defenders, Dazzler, and The Sensational She-Hulk, mostly as an older woman running a modeling agency. In the mid 1980s, she was a recurring character in the Star Comics children's series, Misty, which centered on the adventures of her niece.


The Wells Fargo Tower in downtown Baltimore was sold to Hertz Investment Group for $36.75 million, Hertz announced Wednesday.
The acquisition of the 24-story, 378,010-square-foot office building at St. Paul and E. Baltimore streets was the first in Baltimore for Hertz Investment, a California-based real estate investment firm that has doubled its portfolio in the last five years and now owns 64 properties in 18 states.
The building is 67 percent leased to tenants including Wells Fargo Bank and law firms Whiteford Taylor & Preston, Anderson Coe King and Wright Constable & Skeen. Constructed in 1985, it recently underwent several lobby renovations and the replacement of mechanical equipment.
"We believe Baltimore is poised for substantial population and job growth," said Jim Ingram, Hertz Investment's chief investment officer, in a statement. "Wells Fargo Tower is a property that companies find attractive due to the location, proximity to the courthouse and opportunities for expansion.


text:
Az 1968-as wimbledoni teniszbajnokság női versenyét az amerikai Billie Jean King nyerte az ausztrál Judy Tegart előtt.

Kiemeltek

  Billie Jean King (Bajnok)
  Margaret Court (Negyeddöntős)
  Nancy Richey (Elődöntős)
  Ann Jones (Elődöntős)
  Virginia Wade (Első kör)
  Maria Bueno (Negyeddöntős)
  Judy Tegart (Döntős)
  Lesley Bowrey (Negyeddöntős)

Főtábla

 Q = Kvalifikációból felkerült
 WC = Szabadkártyás
 LL = Szerencsés vesztes
 r = feladta
 w/o = visszalépett

Döntők

További információk
 Eredmények az ITFtennis.com honlapon

N1


But let's be honest - it's intimidating to think about all the time and money that goes into the kind of prep women are expected to do every. single. day. In an effort to see just what this kind of grooming really costs us, I decided to spend a week checking it out, experimenting with products and really giving this whole glossy, done-up thing a try.
To start off, I downloaded beauty/lifestyle podcasts like Lo Bosworth's Lady Lovin', (in which the reality start spends an entire episode cataloguing her daily beauty routine), and browsed through many, many magazines and beauty blogs to figure out exactly what I'd need.
I was advised to invest in face serums, anti-aging products, high-quality makeup, and coconut oil...lots and lot of coconut oil. Having worked in fashion for a while, I'd luckily collected a fair number of these 'essential' items, and began my week already set with a pretty respectable amount of grooming goodies.
Spent the morning plucking, leg-shaving and slathering my whole body with coconut oil, a la advice from Lo Bosworth. After, I felt a bit like I had dipped myself in a jar of Crisco, and smelled like an Almond Joy, so I hopped back in the shower to rub some of coconut residue off. I followed up with a quick swipe of SPF on my face, carefully applied my makeup, and spread Moroccan oil in my hair before a hasty blow-dry.
I woke up and discovered that I actually really like the way my skin feels after my coconut bath yesterday. And my hair looks a bit bouncier than normal too. Alternately, I'm already getting a bit annoyed about wearing my contacts through really long days at work and my face looks a little oily after the excessive lotion, so I spend some extra time with my facial cleanser today. Also on the to-do list: remove chipped nail polish, apply tanning lotion, blow-dry my hair, Nair some of the peach fuzzies on my face (admit it ladies, we all get them), and apply nightly anti-aging serum.
I have the morning off and head over to my local nail salon for a mani/pedi. They have a deal going, so the whole thing only costs $32, plus tip. After nails are polished and dry, I also run over to the spa near my house to get my eyebrows waxed. They're a little pricey, but I can't beat the location and convenience, so I shell out the $28.
Ran out of foundation, so I drive to closest Sephora before work. Construction on the way means it takes 45 minutes to get about two miles. Turns out Sephora no longer sells the kind I use, so I walk away pretty defeated. Drive to the mall on my way home from work, pick up foundation at Nordstrom. Get sidetracked and buy a pair of jean shorts on sale, immediately regret the impulse buy, return the shorts, leave with foundation and samples of bronzers.
Keeping up with this beauty routine is taking up a LOT more mental space than I had expected, but I have to admit that I'm loving the feeling of being a little more...manicured. (Pardon the pun). I spend the evening lathering up with more mild tanning lotion and deep conditioning my hair. Officially know my efforts are paying off when my boyfriend comes home from a business trip and seems genuinely surprised at the change. He asks what I'm doing differently and says I look like I'm "glowing." (Happy face emoji).
Head out on a weekend trip with my boyfriend's family, so my makeup routine, hair-care, tanning lotion application and nail maintenance get amped up a bit. I've never brought so many products on a trip before, and other than the packing issue, it does feel pretty nice to have certain things on hand when I want to spruce up a bit. Highlight? The family exclaims how they love my new haircut - (awkward since I haven't had it cut in ages, but I guess the blowdrying and Argan oil combo is working).
Much the same as the day before except there was a bit of a mishap with my contacts, so I spend an extra couple of minutes battling with plastic in my eyes, but nothing major. I apply one last layer of tanning lotion (why doesn't this seem to work as well as I want it to?) and dab a bit of coconut oil on my face. Have noticed a few breakouts on chin, which is unusual for me, so think I'll back off on the oil/face serums. Also headed to a wedding shower today and look enviously over at my boyfriend as we get ready and he slips a comb through his hair and proclaims he's ready to go. Come home from the party exhausted, ready to put on shorts and a t-shirt and forget about grooming for a while.
Total Time: About 50 mins.
There were definitely some unexpected realizations this week. On the one hand, I was really surprised that some things took a lot less time than I expected they would, yet they still made a pretty big difference. (i.e., blowdrying my hair every day and slathering on some anti-aging creams before bed). On the other hand, I really can't imagine myself spending the time and money on certain routines like getting my nails done every week, eyebrows waxed every three weeks, etc.
Additionally, I really can't imagine spending so much mental energy on setting up appointments, organizing my schedule around when I can get my nightly prep in, etc. Yes, it did feel pretty great to get a few compliments here and there, but (and I mean no offense to anyone who adores spending time priming/getting pretty) I feel like I have more important demands on my time than spending hours and hours on making myself look better according to magazine and beauty blogger standards.
And really, why should I, or any other woman, have to? Appearances matter, yes, and maintaining good hygiene etc is important in the professional (and personal) world, but after this week it became even more glaringly obvious to me that there is SUCH a double standard for women versus men when it comes to grooming. Why is it that my boyfriend could throw some gel in his hair, swipe on some Old Spice, grab a button down and jeans from the closet and declare himself ready to go for the night when I had to spend literally hours getting prepped from head to toe? Needless to say, if I had put in the same effort he did, I would have been considered woefully underdressed and casual while no one would bat an eye at the man next to me.
And the thing is, I didn't even really come close to documenting all the other beauty rituals so many women feel compelled to buy into to keep up. I didn't curl my hair, get spray tanned, submit myself to a torturous bikini wax or shell out for a professional blow-dry. Neither did I get a fresh haircut or highlights, sign up for birch box, or enroll in Soul Cycle/Zumba/Barre/Shred.
In the end, I'm glad I went through with my little experiment. I learned a lot of beauty tricks, but also learned something more important generally: grooming is great, but it is literally impossible for women to keep up with all the the demands the beauty industry demands of us. If outer beauty makes you feel more confident and happy on the inside, then that's great! Go buy that mascara and dominate your next work meeting, date night, etc. But if you're exhausting yourself trying to keep up, my advice would be to take a breather, manage what you can, and know that your beauty truly shines from within.
I actually laughed out loud reading your post. Your commentary on the topic is great. I think it's a really interesting experiment that you took on. I'd be curious to do one of my own! (expect for the extra cost, and the extra time spend, obviously. 😜) Thanks for sharing your experience, it was a great read!
I actually started laughing out loud while reading your post.It was so funny,It is true that women spends a lot of time and money on these.


What determines if a particular file format gets transcoded to FLAC when streaming to an SB2?
If I have an SB1 on the network I can't disable WAV -> WAV, as the SB1 doesn't understand FLAC. But when streaming to an SB2, does SlimServer automatically transcode to FLAC whenenever it can for non-MP3 and non-FLAC files?
What happens in a network with a mix of synchronized SB1s and SB2s? Will one stream as WAV and the other be transcoded to FLAC or will both stream as WAV?
also plays a part in the logic, but that it only controls whether or not a stream is transcoded to MP3. Assume that it's set at 'No Limit'.
> streaming to an SB2?
> What happens in a network with a mix of synchronized SB1s and SB2s?
group, they all get mp3.
trancoding. Choosing a limit between WAV and FLAC is not yet implemented.
natively and avoid teh extra cpu use of FLAC.
> trancoding. Choosing a limit between WAV and FLAC is not yet implemented.
> natively and avoid teh extra cpu use of FLAC.
at the expense of network bandwidth.
I can't see this affecting too many people though.


There are very specific types of businesses that tend to attract investors, no matter the size.
Must be successful and well-established – essentially, it must have a proven product and business model within its market.
What investor would put money into something that wasn't already successful?
You must have a workforce, but ideally only a small one.
Investors are looking for companies that will see their cash injections turn a quick profit rather than be a long-term investment.
A company that develops a proven product but needs investment to scale up their manufacturing process is a perfect opportunity for an investor as a small amount of investment will allow for far more stock being developed and instant sales growth.
A company that provides consultancy as its main product is a much harder sell as training new employees is a far more subjective and long-term consideration than a quick and easy manufacturing expansion.
We've all seen Dragons' Den – the founder and CEO of a company is as key as the business itself. Investors will almost always want at least some control over the business in some regard and that involves forming a partnership with its creator.
You must be fully committed to your company and must be totally certain of its ability to succeed.
It sounds obvious, but investors will be looking for someone who they know is willing to put the graft in and knows exactly how to achieve what they want to achieve.
You must be ready to cede some control.
This is why a work-force is important for investors – in the words of Martin Zwilling, a start-up expert writing for Forbes, investors are looking for people to work with who are working on their companies as opposed to in The day-in day-out must be being handled by a competent team so that you, as CEO, are working on strategy and the bigger picture.
Additionally, you must be willing to both listen to and action the advice of your investors as they bring a wealth of contacts and experience to the table.
You must be honest, realistic and grounded.
Your valuation of your company and belief in its potential can easily be clouded by optimism and sentiment – you must be sure that all the information you give to investors as part of your pitch is as accurate as possible. Independent auditors can provide an external, impartial view.
Leading on from the above point, even if your business is proven and you are a strong candidate, if you don't have a clear, achievable and realistic business plan for them then they simply won't be interested.
Use market research to demonstrate potential.
There are a number of companies that can either be hired directly, or have resources that can be purchased, that demonstrate the market trends within the industry your company operates within – find trends that demonstrate that your company can upscale into a successful operation.
Make sure your plan is as streamlined as possible.
Upscaling means growth, but this growth should always have best practice and streamlining of processes at its core. Automating production is a good example of this as opposed to expanding the workforce unnecessarily.
If you are looking for globalise your company, looking at licensing and franchising as means to develop in a less labour-intensive way.
Ceding control to others with market experience abroad is a good means of working on the business without being in it – intricacies are dealt with in a streamlined manner but the burden isn't yours to shoulder.
If you stick to these three core principles, you'll be batting the investors away with a stick. Make sure you pick the partnership and the deal that is best for you and your company and who knows where you'll go – the sky's the limit!


पिछली टिप को देखने के लिए क्लिक करें How to open Blocked Torrent? टोरेंट को कैसे डाउनलोड करें?
Hi, In the last video I have shown you how to create a school ID Cards using print merge command in CorelDraw. In that video I have also shown you how to use a macro to place an image at a fixed location now in this video I will show how you can use a shortcut key to a macro so that image can be placed automatically to its specific location.
How to create a school id card using macro in this video you will learn how to create student ID cards using macro and place image on the cards very easily.


text:
HARVEY HEROES — What did we learn from historic storm?
Published 12:38 am Sunday, June 26, 2022
A truck stranded under the Memorial Boulevard train trestle. (File photo)
When Hurricane Harvey downgraded to a storm, many in Southeast Texas were relieved. However, as the storm popped back into the Gulf of Mexico after making landfall near Corpus Christi, meteorologists began to warn of potentially heavy rains.
No on expected the largest rain event in the country's history. But after more than 60 inches of rain submerged much of Southeast Texas, many were left without options but to rebuild or move.
Since Tropical Storm Harvey, Southeast Texas was also the scene of the fourth largest rain event in the United States behind Tropical Depression Imelda in 2019. After Harvey, many rested on the idea that a storm that size would likely never happen again, but Imelda removed any remaining comfort.
The storm forever changed the way area entities prepare for and react to rain events.
In the aftermath of Harvey, Port Arthur Independent School District faced dealing with a majority of the student, teacher and staff population being displaced.
"We learned you have to always be prepared," Superintendent Mark Porterie said. "Living in Southeast Texas, you never know. The flooding came up on us and we were watching the water rise. We didn't really think about leaving until it got so high that we couldn't. I think we are a little more cautious about that."
Porterie thinks people are more likely to heed the warnings of weather reports in the future.
"From a district perspective, we learned that we are resilient," he said. "People came together as a district and a community."
Porterie pointed to other challenges the district faced that will help with the next inevitable major rain event. In 2020, the district switched to virtual learning as a response to the pandemic. Having the ability to go virtual at the drop of a hat could make the district more resilient and respond quicker in the wake of another natural disaster.
"I would think with the experiences from Harvey and COVID, the district could move along very well with instruction," he said. "We have upgraded. Every student has a device. Our teachers have had the experience of teaching virtually. Our students understand virtual and like it for some reason. I think the experiences we have had strengthen us to say the least."
While districts have focused on how they will respond to the next event, city municipalities have worked on preventing the next tropical storm from having such devastating affects.
Nederland, like many cities, has worked on getting grants to fund several mitigation projects, most of which are aimed improving drainage.
"It is hard to prepare for five feet of water," Nederland City Manager Chris Duque said. "Nederland still has the record. It clearly showed the importance of drainage. We have put more resources into that. It identified some trouble spots locally. So much of the grant funding that has come out since that storm has been for more of a regional approach instead of just a community or a neighborhood. They want to look at the impact and how downstream or upstream these problems are happening."
Duque said the city is working on projects that are the result of funding from Harvey.
"We are actually going to authorize a bid on Monday for one of our biggest drainage projects," Duque said. "It is using Harvey funding. That is how long it has taken to get the money out the door and put shovels in the dirt."
The city manager said the project would look at the Hildale and Hilterrace area between Highway 365 and Avenue H as well as the area between Nederland Avenue, Gage Avenue and First Street.
"I think the number of people that will benefit is about 2,00 people," he said. "For a town of 17,000 people, that is a good project."
Duque said Harvey changed the way many looked at tropical storms.
"I don't think I can remember a tropical storm doing something like that with that volume of rain," he said. "That was totally different. Usually when we do these tropical weather events, we are more inclined to look at the wind that is coming and the storm surge. You are so used to a hurricane coming and you know you have to ride it out for several hours as it passes over you. Harvey just meandered and plopped down and dumped a huge amount of rain."


Be kinder than you think you need to be–everyone is fighting their own battles. I saw this note on a break room refridgerator at a healing center. I loved this sign so much, I wanted to make t-shirts.
In our society, we don't know when someone is grieving. They don't wear black armbands. They might get a day, or two, or three off from work. Then they're expected to go back, and be 100% productive. I can guarantee you, they are not.
I have friends who are grieving right now. I remind them frequently that grieving is the hardest work they'll ever do. They do it 24 hours a day, even when they're asleep. Their brains are tying to adjust, to make sense of the loss. I remind them to take their vitamins, get lots of rest, give themselves permission to do only what they feel like doing. I encourage them to take their own car and follow instead of driving with a friend. Going out to dinner, or a movie, or even a party may seem like a good idea at the time. But in a split second, it may become too overwhelming, and they may wish they were anywhere else. A person who is grieving may want a hug, and the minute they are embraced, they may feel claustrophobic. It's a difficult time. Emotions can vary from moment to moment.
This saying also applies to people who are dying. Some people become short with their caregivers who are often the people they love the most. Stephen Levine says that the flu prepares us for death. I understand this. I know when I had the flu a couple of times, there was a point where I was suffering so much, that I pretty much felt willing to die. Of course, I wasn't really dying so this was just a concept. If I had been dying I might have felt differently. I can't know. But I do know that I was a bit short with my caregiver who was only trying to help. "No I only want a coke and dry toast, not soup." Couldn't he see how sick I was? Couldn't he read my mind? Of course not.
So I encourage you (and remind myself) Be kinder than you think you need to be–everyone is fighting their own battles.


Here are 3 tips to improve sales in the F&I office.
Introduce the F&I advisor before closing the sale. Be transparent about what the customer should expect later on, including F&I products, insurances, and potentially starting the credit approval early on. It breaks down walls later – a hurdle you won't have to jump.
2.	Focus on the Customer's Needs!
The needs assessment tells you exactly what the customer would benefit from the most. Focus on what serves the customer best, then introduce other valuable products. It's a great way to start the conversation with 'yes' as an answer.
There's always the one thing you don't like to sell or just can't do well. Don't skip it – feature it! Make it one of your highlights in the product demo.
Tip of the Day - You're Selling Preventative Maintenance Wrong!


text:
The Festival 2023
About GAIA
Circle of Friends GAIA
Experience GAIA
Read Newsletters
GAIA Collection
Artists and Premieres
Programme|
Musicians|
GAIA 2022
on Lake Thun, in Thun and Berne
The Cradle of Musical Genius
Thursday 4 to
Oberhofen Castle
The Town Church Thun
Hilterfingen Church
Scherzligen Church
Berne Music School and Conservatory
Yehudi Menuhin Forum, Berne
> GAIA 2022 – Programmheft
Gwendolyn Masin, founder and artistic director
fam·i·ly, ˈfam-lē, ˈfa-mə-
Plural: families
Family: a group of persons united by the ties of marriage, blood, or adoption, constituting a single household and interacting with each other in their respective social positions, usually those of spouses, parents, children, and siblings.
No matter what our feelings towards the term "family" and our experiences of it are, we all have one thing in common at the very root our existence: we are born by our (biological) mother. With a festival named after the primeval Greek goddess who represents the Earth, it seems fitting that I go in search of outstanding female composers in classical music, as well as their male counterparts.
The idea of a family-themed festival formed in my mind in 2017 when I became intrigued by the Boulanger sisters, their music and the support of the elder sister for the younger. I began to study composer families—the Bachs and Bendas, Nina Makarowa and her spouse Aram Khachaturian, Alexander Scriabin and his son Julian, the siblings Bacewicz and Gnessin, the Tcherepnins, Vačkářs and von Herzogenbergs and, from Solothurn, Richard Flury and his son Urs Joseph. Their stories were full of promise, brilliance, hard graft and the desire for recognition, success and failure, patriotism and independence. Certainly, they were stories that orbit around love.
The lack of a greater number of female composers up until the middle of the twentieth century is the result of social prejudice and patriarchal mores up to that point. Defying these restraints as best possible are, amongst others, Fanny Mendelssohn, the sister of Felix; Clara Wieck, the wife of Schumann and muse of Brahms; Kateřina Kolářová, the wife of Smetana, and Irina Regina Wieniawska who published under a male pen name as the burden of her famous father's legacy weighed heavily on her shoulders. The women that are woven into this year's rich tapestry of music at GAIA are composers and musicians themselves, not just muses to a man's inspiration.
Adding to the family theme are the performers themselves who are all related to one another. There are brothers and sisters, fathers and daughters, fiancés, spouses, musical partnerships, and decades-long academic relationships.
A fourth-generation musician with roots in Hungary, the Czech Republic, and the Netherlands, I have spent formative years in Ireland and have lived nearly half my life in Switzerland. I have the good fortune of being continuously encouraged by my family and have experienced, not the burden of sexism, but the never-ending search for identity both within my family structure and beyond. There is great strength to be drawn from the awareness of multi-ethnicity. There is, however, also a prevalent feeling of having no physical roots, of dangling in the air, of not having access to what "tradition" can mean amongst those who cultivate it in one and the same country.
But there has always been family to keep me rooted. Family and music. May both illuminate your days as we welcome you to this year's festival!
Gwendolyn Masin,
Founder and artistic director
GAIA Music Festival Oberhofen
Founder and artistic director:


text:
Posh Secure Loan Signing Of Leeds Defender
Denton arrives at the ABAX Stadium.
Joe Dent / theposh.com
Tyler Denton signing for Posh
@theposhofficial
Steve Evans completes loan signing of left-sided Leeds United player.
Peterborough United have bolstered their defensive ranks with the signing of Leeds United defender Tyler Denton on a season-long loan with the 22-year-old completing the paperwork at the Mick George Training Academy on Friday morning.
Denton, who has enjoyed a loan stint with Port Vale in his career to date, came through the Academy at the Whites and has made one appearance for the England under 17s. He has a handful of cup appearances to his name with the Elland Road club and knows manager Steve Evans' well from his time in charge at the Championship club.
Evans said: "We know Tyler very well from being in and around the first team squad at Leeds United. We elevated him and Bailey Peacock-Farrell, who is now doing well in the starting line-up, into the first team group and he did exceptionally well. It is fair to say that he has developed further with a few games in the first team at Leeds. I watched one of those games where he scored the winning goal against Luton Town and he was very impressive.
"He had an excellent spell on-loan at Port Vale last season but he has gone back into Leeds and we are absolutely delighted to bring him into our squad and he will compete anywhere on that left hand side for a place in our starting XI. It is massively important that we bring good footballers in and Tyler Denton is a good footballer, he works really hard and for one so young, he has an excellent pedigree.
"He has played with some top class players at Leeds United over the last few years. Leeds United supporters know their football and they rate this lad very highly and this is about him furthering his education and to go back to Elland Road in a year's time ready to compete at their level. First and foremost, he needs to focus on what is in front of him now and what he does in this loan spell will determine what happens for him in the future."
Denton, who has been in the Leeds Academy since he was six-years-old, was pleased to finalise the details on the loan deal and cannot wait to get started. "I had a discussion with Leeds in the summer and we both felt it was the right time to try and get a long-term loan deal and play some first team football.
"I was only young when Steve and Paul were at Leeds, but their record speaks for itself and I cannot wait to get started here with Peterborough. I am feeling fit, I have been training with the under 23s at Leeds and now it is about playing pre-season games. I am a full-back who likes to get forward and support the attack, but more importantly, it is about stopping crosses and defending well."


Are your looking for the best bulking cycleprogram that helps you to pile up quality mass and gives you a lean, hard physique? If so then you first need to determine your goals as the best bulking stacks would largely depend on what results you wish to achieve through the steroid bulking cycle. Whether you are an athlete or a bodybuilder or someone who is only keen on building muscle mass- who you are would determine your goals required for shaping up the best bulking stack and bulking cycle. Regardless of the camp you join for adding mass to your body, steroid and bulking stacks would have similar effects but the results they yield would vary depending largely upon the diet, training program and also the dosage you follow.
Settling down on the best bulking cycleto add to quality mass to the body in the shortest time possible, most effective manner and safest means is a little difficult. Find out about the steroid bulking stack and bulking stacks to determine how to pile on the mass and get the desired dream body.
Any anabolic steroids can help you in adding mass but look for bulking cyclethat contain certain compounds, which are more effective than others in producing the most gains in the fastest time possible. Steroids used in bulking stacks will help you gain mass and blow you up. Many believe that the best building stacks would contain testosterone as their base compound that it is well-accepted by most bodies and it stacks well with other effective compounds. Often bodybuilders and hard gainers go in for bulking cycle, such as Nandrolone Decanoate and Danabol and mention them as the best steroid bulking cyclefor gaining mass.
Try asking a few famous bodybuilders about the best bulking cycles, they may point towards a combination of Androlic and Danabol as well as Testosterone with Nandrolone Decanoate. These bulking steroids have been used by a lot of hard gainers and bodybuilders with extreme level of mass for fully building stack. However, some experts in this field often discourage bodybuilders to mix Androlic and Danabol for the high level of toxicity it produces when combined together. This steroid combination considered to be the best building stack and best steroid bulking cycleare said to have long-term side effects on the body, often proving to be harmful for the body. Thinking it to be the best steroid bulking cycleand bulking stacks can prove to be a grave mistake.
When you are trying to look all mass then you may try Dianabol, It is said to be one of the best steroid bulking cycle. The popularity of this steroid as a best bulking stack can be attributed to its rapid effect in helping one gain muscle mass and strength. The short-6 week dosage of this steroid and the reason that it is cheaper and easily available in a variety of does makes it a favorite bulking stack for many bodybuilders. However, judicious use of this steroid bulking cycleand critical planning before taking it is necessary to ensure that it doesn't have serious negative effects on the body. These anabolic alternatives can be combined with testosterone boosters which are chemically-free of steroids to give bodybuilders safer options to build mass.
Trenbolone is not the best steroid for building stacks as critics would point out. Though it is popularly considered for best cutting substances that add on lean mass, users of this bulking stack would tell you that it can be quite unreasonable and painful to take trenbolone injections every day. Besides bearing the pain of the daily injection, trenbolone can also have terrible effects on cardio shape of the user. It is best to add this bulking steroid with an already effective steroid cycle such as Testosterone and Danabol.
The list for best bulking cycles also includes mention of Boldenone as it has the effectiveness to make its users huge. It is one of the best bulking stacks known for enhancing the appetite, it is better than even B12 injections. Someone looking to increase the red blood cell count can also opt for this best bulking cycle. Use of this best steroid can also make cardiovascular seem like an easy task.
Set you goals on achieving the lean mass before you decide on the best bulking cycleto follow. The outcome and the quality of results would be determined by the objectives you set before the steroid cycle. It is tricky to say which would be the best steroid but it is easier to determine as to which steroid bulking cycles would help you reach your goals.


Christmas preparations are now in full swing, with so many presents to buy and food to order. UncommonGoods is here to help with a host of unique, fun gifts for the whole family. Finding that Christmas present that is just perfect for your loved one can be difficult, but with so much inspiration for all price ranges UncommonGoods has something for everyone. It is an American company founded in 1999 with a focus on sourcing unique gifts, designer décor and handmade presents. As they are an independently-owned business it allows them to support causes they believe in through their Better to Give program, so with every purchase they donate $1 to the non-profit of your choice. Since starting the program 12 years ago UncommonGoods has donated over $1 million to charities over the world!
They have also been awarded every year since 2007 for outstanding customer service, which as a customer is such an important part of our shopping experience. In 2015, they even achieved the BizRate Platinum Circle of Excellence Award for such impressive customer service. The combination of unique gifts, donating to charity and excellent customer service is a winner with me!
The one thing to bear in mind when ordering from UncommonGoods is that they are based in New York, America so delivery is more expensive. Your order will be delivered between 4-7 business days, which is a similar time to ordering from within the UK but it is worth checking because there are some products that aren't available to be delivered to the UK. This is clearly displayed next to the 'add to the basket' button on each products page when you have it set to deliver to the UK.
Which is your favourite gift under £30 for children from UncommonGoods?
I think my bank balance is going to shoot down. What a great website idea.
This is such a great list with some really nice presents on - I particularly like the construction plate, the named rolling pin and the cute penguin slippers!
Ooh, so many cute ideas!
I know a few adults that would be into that lamp! Great gift guide!!
I have just bought the construction cutlery set for Harry for Christmas - it's fab isn't it? These are such lovely items, gorgeous collection!
You have picked out so easy amazing games pieces. That plate isso cool, my youngest son would love it.
What lovely and unusual gift ideas. I love the ethos of the company too, and that they donate to charity. Sounds like a great company to deal with.
The unicorn hangers and the animal ears are so cute and girly!


text:
Search results for "gen Z"
Gen Z's
Gen Z audiences
Gen Z Marketing
App Annie Releases New Gen Z Report With Insights on Winning Over the Mobile Generation
PRNewswire	 Oct 21, 2020 0
App Annie, the leading mobile data and analytics company, released a report on Generation Z, How to Build a Winning Gen Z Strategy on Mobile, that reveals the mobile habits of this generation to help businesses understand and cater to this group. Gen Z is quickly becoming one of the world's most powerful consumer segments - as one of the youngest generations, Gen Z amounts to a third of the world's population and controls an estimated spending power of $143 billion annually. With 98 percent of Gen Z owning a smartphone,…
Yubo, the Leading Social Space for Gen Z, Opens New London HQ
MTS Staff Writer	 Sep 16, 2020 12
Announced new hire of major product and safety leads for the UK and across the globe Yubo, the top platform for young people to socialise online, announces two new major hires who will form a part of the app's new London office, further strengthening the business' recent significant growth in the UK. The new members of the team include Benjamin Trigalou, former Product Lead for Waze who will lead design for Yubo, and Margaux Liquard, Yubo's new Lead Safety Manager, whose former roles include prominent safety positions…
Valassis Research: Gen Z – Chasing and Redefining Value in Multiple Ways
MTS Staff Writer	 Aug 3, 2020 0
New Data Illuminates Fresh Opportunities as Behaviors Shift Valassis, a Vericast business and the leader in marketing technology and consumer engagement, today released its annual Consumer Intel Report, "Chasing Value: The Mind of the Modern Shopper." The annual report examines responses from more than 2,000 U.S. consumers in two separate surveys, noting how their shopping patterns and purchasing decisions have changed within specific categories including food, household goods and health & beauty care products amid the…
The Privacy Pendulum: How Millennial and Gen Z Perceptions of Search and Privacy are Changing
Tal Jacobson	 May 18, 2020 0
As digital natives and early adopters of the technologies that have shaped the 21st-century economy, Millennials and Generation Z are hardly tech skeptics. But amid high-profile data breaches and mounting scrutiny into how companies like Facebook and Google have harnessed users' data, young adults have grown more skeptical about data collection. These younger generations are increasingly distrustful that internet companies are responsible stewards of their most sensitive information, whether it's being used to target users…
How Brands Can Connect with Gen Z through Social Media Marketing
Aaron Brooks	 Apr 21, 2020 6
Most Instagram users will be somewhat familiar with the fashion brand Revolve. The company has successfully used celebrities and mega influencers to boost brand awareness and turn the label into a billion-dollar success using Social Media Marketing. Revolve attributes its Influencer Marketing strategy with bringing in as much as $650 million to $700 million revenue a year - and now, it is further taking that approach to the next level, with the launch of a new, Gen Z focused label called Superdown. Revolve's approach…
VideoElephant Partners With Gen Z Video Publisher Zoomin to Expand Its Video Library Offering
PRNewswire	 Mar 17, 2020 0
VideoElephant, a global aggregator and distributor of video content, is delighted to announce its partnership with Zoomin to bring additional premium content to its library. Zoomin is one of the world's hottest online video publishers. The company produces hundreds of high quality videos each month in nine languages, targeted at one of today's most influential audiences, Generation Z. The VideoElephant library hosts over 2 million videos made available in global markets, across a range of genres and languages. The…
Cassandra's "The Culture Of Influence" Report Reveals What Makes An Influencer Effective With Gen Z And Millennials
PRNewswire	 Mar 6, 2020 0
Report Offers Insights on Influencer Impact on Gen Z and Millennial Purchasing Behavior A new trends report, "The Culture of Influence," released by Cassandra, ENGINE's insights and strategy group that studies trendsetting young consumers, reveals the key characteristics and strategies that drive the relationship between influencers and consumers. The report takes a deep dive into the influencer space today to understand what gives influencers their influence and what brands need to do to be successful in the space. It…
Best Tools to Connect with Gen Z on Instagram
MTS Staff Writer	 Mar 4, 2020 0
As Generation Y grows older, a younger generation is now emerging into the workforce. Generation Z, or Gen Z, is anybody born from the mid-'90s to the mid-2000s, and they're the following age group to influence the buying process. By 2020, Gen Z is expected to account for 40% of entire customers. A study says "Age Z is one of the most impressive shopper powers in the market today. Their purchasing power is $44 billion and grows to $600 billion while considering the impact they have on their folks' spending. If you…
Teads Now Connects Advertisers to 88 Percent of Gen Z and Millennial Consumers According to Comscore
MTS Staff Writer	 Feb 25, 2020 0
Teads and Bustle Digital Group Sign Exclusive Partnership Expanding Teads Reach in US Teads, The Global Media Platform, announced it signed an exclusive partnership with Bustle Digital Group (BDG) expanding its reach to 88 percent of consumers across the Generation Z and Millennial age groups in the US according to ComScore. Under the partnership, Teads will enable BDG to increase incremental ad revenue from video and viewable display across mobile and desktop. BDG is the leading digital media company publishing…
Connatix Research Shows Gen Z Prefers Multifaceted Content Experiences
PRNewswire	 Feb 21, 2020 0
Compared with Millennials, Gen X, and Baby Boomers, Gen Z prefers content that includes audio, video, polls, quizzes, and a means to comment and receive recommended stories Connatix, the next-generation video technology company for publishers, announced the findings of a study it conducted about the media consumption habits and preferences of Gen Z, that indicates members of this generation (aged up to 22 years) gravitate toward a "multifaceted content experience," rooted in user recommendations from a diverse set of…
The Changing Customer: Reaching Gen Z During the Super Bowl and Beyond
Paul Josephsen	 Jan 31, 2020 0
The Big Game continues to be the go-to venue for the world's top brands to spar against each other for the public's attention. Year after year, we're blasted with 30-second, multi-million-dollar ads that not only seek to thrill, inspire, entertain and delight — but imprint themselves on our psyches. In the same way, NFL teams see the Super Bowl as the final test of the gridiron, brands and agencies see it as a winner-takes-all competition of television salesmanship. Gen Z is expected to account for 40 percent of all…
New Gen Z Data Brings Businesses a Critical Question: What's Your Plan Z?
PRNewswire	 Jan 30, 2020 0
E-Commerce and Mobile Commerce
EY research uncovers five distinct Gen Z segments that employers and business leaders need to know Employers and business leaders take note: a one-size-fits-all approach to defining a generation will cost talent and customers. As Gen Z, the generation of those born between 1997 and 2007, begins to enter the workforce and flex its newfound spending power, connecting with them is critical. To do so, it is important to identify and acknowledge the differences within the generation — something many employers and…
A Crash Course in Gen Z's Obsession with Creator-Driven, Influencer-Heavy Streaming Content
Rob Israch	 Jan 24, 2020 0
Ads and retargeting are accepted, measurable Marketing channels, but if you're trying to garner attention from the next wave of consumers, you need to engage the community of streamers, creators, and/or influencers. The advent of digital media platforms like YouTube, Twitch, Twitter, TikTok, and Facebook/Instagram has created a new form of engagement that relies on a more intimate two-way relationship between creator and audience. Marketers and brands can effectively utilize this if they get over their preconceptions and…
As Gen Z Is Set to Rewrite the Future of Mobile, App Annie Releases Report to Help Companies Win With This Next Generation
App Annie, the leader in mobile market data and analytics, released a groundbreaking report on Generation Z, How to Win Gen Z, a demographic that's now the largest population on Earth and the mobile-first generation. This report is essential for businesses to gain insight into this emerging economic engine to fuel revenue and relevance for the long term. "Gen Z is the first generation to grow up on mobile," said Ted Krantz, CEO of App Annie. "They already influence $600B in spend in the US alone—companies need to aim…
Brainly – One of Gen Z's Top Homework Resources – Launches New Native Ad Offering for Mobile and Desktop
Native & Programmatic Advertising
General Assembly Leverages Brainly Native Ad Units to Increase Awareness and Drive Student Engagement Brainly, the world's largest peer-to-peer learning community for students, parents and teachers, has announced the launch of a new native advertising capability on its platform. Brainly native ad units provide advertisers a unique opportunity to reach and engage on a deeper and more meaningful level with more than 10 million Generation Z (Gen Z) users in the United States. Native ads are available for both mobile and…
Future of Brand Marketing: How to Acquire Gen Z Customers in 2020-2025
Sudipto Ghosh	 Oct 29, 2019 0
Our Gen Z customers keep us on their fingertips. With only the last few weeks of the decade remaining, we thought of breaking the mold that most marketers may have found themselves stuck into. Most Retail and Omnichannel Marketing teams have indeed been laser-focused at targeting the Gen Z population for most of the years between 2005-2019. And, the trends have translated into unprecedented growth and popularity for a wide range of websites, mobile applications, and digital advertisement platforms. To name a few, Facebook,…
90 Percent Of Gen Z Tired Of How Negative And Divided Our Country Is Around Important Issues, According To Research By Porter Novelli/Cone
Marked increases in Gen Z's belief companies must address hot-button issues like gun control and LGBTQ+ rights Nearly nine-in-10 (87%) of Gen Zers are worried for the environment and the planet, according to the 2019 Porter Novelli/Cone Gen Z Purpose Study. The study, surveying Americans ages 14-22, examines this emerging generation's expectations of and attitudes toward company involvement in social and environmental issues – and the actions they are willing to take to positively impact topics they care about. "The…
Gen Z Sales Teams Don't Have Time to Stop and Sign
Garret Schwartz	 Oct 10, 2019 0
Maximize Sales Momentum with the Right One-Stop Sales Enablement Platform Think about that last great deal you closed — the momentum you felt as you cruised from pitch to close with zero friction, zero hold-ups, and zero hurdles. It's a total rush, and it's totally good for business. This positive momentum has been tied to everything from increased confidence to seeming more competent to overall professional success. Very simply, high-performing Salespeople experience positive momentum more frequently — and are more…
How Better Mobile Onboarding Can Help Banks Target Millennials and Gen Z
Zviki Ben-Ishay	 Sep 30, 2019 1
In June 2019, JPMorgan scrapped Finn, its mobile banking app aimed at Millennials, after only a year in business. The move left other financial institutions questioning the fate of similar programs such as Wells Fargo's Greenhouse and Goldman Sachs' Marcus. Were these sleekly branded products actually effective at attracting Millennials? If not, what tactic would be? These are urgent questions. Banks today struggle to hold onto younger customers: Millennials are 2.5 times more likely than other generations to switch banks…
The Gen Z Effect: NCS and Snapchat Quantify Gen Z's Influence on Household CPG Purchases
Business Wire	 Sep 26, 2019 0
Our youngest generation wields a considerable influence on household buying, new study shows Move over celebrities and micro-influencers: The youngest consumers among us just might be the hottest new influencers in town. NCSolutions, the leading company for improving advertising effectiveness for the entire CPG ecosystem, announced results from an innovative meta-study in partnership with Snap Inc., creator of Snapchat. Based on the measurement of 19 CPG Snapchat advertising campaigns across 32 brands and almost 4 billion…
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Extract of fruits from eight cultivars (Kwaasi et al. 1999). After washing the fruits, the seeds were aseptically removed and then extracted in phosphate-buffered saline (PBS, 1:5 w/v). Afterward, 2% polyvinylpolypyrrolidone (PPVP), 2 mM ethylene-diaminetetraacetic acid (EDTA), and 10 mM diethyldithiocarbamate (DIECA) were added to prevent proteolysis, and thiomersal (0.02%) was added as preservative. The slurry was centrifuged (20 000 g for 30 min at 10°C), and the supernatant was extensively dialyzed (4°C, 72 h) and freeze-dried. Some lyophilized samples were reconstituted in distilled water (1/10, w/v) and glycerinated (1:20 w/v) for skin testing.
Fresh date and extracts (Gonzalo et al. 1997). Crushes dates without seeds were extracted at 20% (w/v) by shaking for 1h at room temperature in ammonium bicarbonate 50 mM, pH 8, followed by 30 min, 10°C, centrifugation at 20 000 g. The supernatant was filtered, delaysed against water, lyophilised and stored at 4 until use.
Protocol: (controls, definition of positive etc)Prick-prick technique. Saline solution was used as a negative control and 10 mg/ml phosphate histamine as a positive control. Reactions were positive if the largest wheal diameter was > 3 mm (Gonzalo et al. 1997).
19 patients (Kwaasi et al. 1999).
All the 19 patients were SPT positive to at least two fruit extracts (Kwaasi et al. 1999).
Extract fruits from eight cultivars (Kwaasi et al. 1999). After washing the fruits, the seeds were aseptically removed and then extracted in phosphate-buffered saline (PBS, 1:5 w/v). Afterward, 2% polyvinylpolypyrrolidone (PPVP), 2 mM ethylene-diaminetetraacetic acid (EDTA), and 10 mM diethyldithiocarbamate (DIECA) were added to prevent proteolysis, and thiomersal (0.02%) was added as preservative. The slurry was centrifuged (20 000 g for 30 min at 10°C), and the supernatant was extensively dialyzed (4°C, 72 h) and freeze-dried.
Date extracts (Gonzalo et al. 1997). Crushes dates without seeds were extracted at 20% (w/v) by shaking for 1h at room temperature in ammonium bicarbonate 50 mM, pH 8, followed by 30 min, 10°C, centrifugation at 20 000 g. The supernatant was filtered, delaysed against water, lyophilised and stored at 4 until use.
RAST, ELISA and Immunoblotting (Kwaasi et al. 1999 and 2002).
19 patients (Kwaasi et al. 1999 and 2002).
RAST was 1+ in 3 patients, 2++ in 3 patients, 3+++ in three patients and 4++++ in other 4 patients. IgE ELISA results revealed that sera from seven of the patients in whom positive SPT responses were elicited to the different extracts gave relatively low ELISA scores (Kwaasi et al 1999).
Patients reacted to two main bands of 14 and 30 kDa (Kwaasi et al. 2002).


We were so excited to meet Amber and Mike in their Patriot, Indiana home on the countryside for their engagement session this past Spring. They have a stunning lake and pier in front of their home, so it was a natural setting for great portraits. To have the sun setting behind the lake made our job very easy! After our engagement session with them, we knew we could get some great shots at the wedding.
The details and care that were put into this beautiful Fall themed wedding were impeccable. We loved their handmade flowers made by Amber's grandmother, and homemade food that couldn't have been better. And boy, this gang knew how to party! When you live in the country, you can turn the music up as loud as you'd like and have the biggest bonfire around, and these two took full advantage!
Thanks Amber and Mike for letting us be a part of your day. We loved capturing your perfect day and hope you love the photos!


As we age, God shows us more how we are, in the end, unprofitable servants (Luke 17:10). As Lewis said, "All this is flashy rhetoric about loving you; I've never had a selfless thought since I was born." Any godliness noticed by others in widescreen pales when we consider our minute-by-minute lives. We don't need a microscope to see our countless, faithless thoughts, words, and deeds. Therefore, a hearty "Amen" to this observation by R.C. Sproul. Consider it.
I like to poke at classic rock, but occasionally its old warhorses assert themselves. Apparently some video game has awakened interest in this song by Kansas. It was written by the band's lead guitarist, Kerry Livgren, in the midst of a journey that led him to Christianity several years later. That journey is well-reflected in these Prodigal Son lyrics (cf. "The Wall" from Leftoverture). Equally notable here is the caliber of the music: great harmonies, songwriting, pinpoint accuracy, interesting parts galore, and the cohesiveness of a talented band at its creative peak. It's amazing that they came anywhere close to recreating it without a tape machine, but here it is… live! Livgren is the blonde dude.
Even mushy evangelicals aren't enamored of feminist harpies. You know, the wild hairs who march around with coat hangers. But I find "Christian egalitarians" far more offensive. They deny things that no one seriously denied for two thousand years. They speak in measured tones about "mutual submission" and "creating opportunities for women" while reading their TNIVs and denying the authority of Scripture. That's really what the whole debate about feminism, just like the debate about homosexuality, comes down to: denying that the Holy Spirit has come along as intellectually and morally far as us moderns.
When we went through marriage counseling last century, my pastor at the time pointedly remarked how ridiculous it was to see women driving men around town. He imitated a guy sitting like a lump in the front seat, with the lady doing the work and leading the way. I think that remark came on a day when my wife-to-be drove me to the church. Now I drive most of the time.
Another area where I have come to find a cheap and fresh joy is in seating my wife in the car before I get in. It seemed unnatural at first, but now I get such as pleasure from it that I can barely bear to not do it. It's too enjoyable to miss. Similarly, it's fun to let my wife off at the front door of a restaurant while I go park and trudge through the snow or rain. Does she appreciate it? You bet she does. My love and service is lacking in many other areas, but these minor victories are a small picture of Christ's joyful service for us. As John Piper is fond of pointing out, Jesus endured the cross for the joy set before Him (Hebrews 12:2).


Download yet another famous game hacking/alteration tool from our site and start to enjoy hacking games in your desired way. This app is very similar to "Game Killer" and "SBMan Game Hacker" by which you can easily bring modifications the money, coins, scores and games in your desired way only in an offline game. But this app does not working on paid games so you can hack only free games with the help of this astonishing Android app. Just take a risk to hack any free offline game on test basis either GameGuardian works or not. It doesn't allow you to encounter with online games.
With the help of GameGuardian you can scrutinize for score values in your game and once the value is found, you can modify it to the value that you want. Assume that you have scored 300 points in your much-loved game and search for 300 numeric values in GameGuardian it will give you the results. So then you can easily change your score from there by putting the values that you want, for example, 300000 in a particular area.
This APK offers you several searching options by which you can find the core values even if these values are not entered correctly. When you specifying the difference the search values between the defined ones as well as explicit and fuzzy ones the APK makes searching more flexible and powerful for known and unknown score values in offline games.
The app runs on ARM, x64 and x86 device including x86 emulators.
This app supports Android 2.3.3 and up and also supports Lollipop 5 and above, Marshmallow 6 and above, and Nougat 7 and above.
With this hacking app, you can search encoded values.
You can also search for unknown values by specifying them the difference between values.
Users can easily make modifications in all search results at once.
The app supports 32-bit applications on 64-bit devices using speed hack.
You can filter of all search results by using this app.
The tool only works on rooted devices.
The GameGuardian is a multilingual app which supports more than 90 languages.
For the above features and much more just download the App's APK file from below and install the app on your Android device or tablet and enjoy hacking all type of offline games with GameGuardian on the go.
Once you download and install, it will make sure that you never ever get out of coins and points while playing your most loved games. With this app users can also unlock unlimited stages and you will never stay curious about any stage. Please remember that this will not support to hack online games or any game needs Internet connectivity for play.
Please note that the GameGuardian works only on rooted devices! So it needs root access, as a result, you must root your Android device or tablet before using the app for hacking any offline game. You can't able to hack any online games because this app does not support hacking online games.
Please also note that you can use this app only for ethical hacking of offline games, it cannot support for any unethical or illegal misdemeanours. Moreover, if you fail to get your desired results or you fail to modify the game scores and coins then you can also check SBMan Game Hacker and Game killer game hacking apps. These game hacking apps also work in same way as GameGuardian does.
So download the APK file of the GameGuardian from below and enjoy hacking offline games with this incredible Android app.
The APK of GameGuardian is offered by d2dyno and it requires Android 4.4 and up.


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ballet shoes number 5 birthday machine embroidery applique design-4x4,5x5,6x6 inch
Allen's birthday fell three months after the Ghost Ship fire, and the day passed without the typical call from his sister, whom he says was one of his closest friends. A few months after that, his second child was born, and Allen realized both the little boy and his now two-year-old daughter would grow up without knowing their Aunt Amanda. To cope with their grief, Allen's two brothers and their parents — who all live near each other outside of Boston — have made it a priority to get together regularly, for everything from birthday celebrations to fall trips to the pumpkin patch.
Wearing a tuxedo, Kasper, who has his own Facebook page at www.Facebook.com/kasperandfriends, will be accompanied by his owner, Matt O'Connor, of Concord, Kids of all ages are invited to participate in the less than three-quarter mile, 30-minute parade that will walk up Broadway from Chula Vista to Capuchino Avenue, where it will turn right and circle back down Broadway, Pet owners who wish to march with their pets must be at the parking lot near Broadway ballet shoes number 5 birthday machine embroidery applique design-4x4,5x5,6x6 inch and Chula Vista avenues by 9:30 a.m, There is no fee to participate, and water stations will be provided for pets..
Nastia Liukin and Derek Hough were a very close fourth, getting 9s and 10s for a jazz waltz that embodied everything Disney. Their dance from "Frozen," with great moves and technique, finished off the night, but I still liked Ursula the best. The only lowlight was just a blunder. Robert Herjavec and Kym Johnson had the quickstep, a really tough dance, to "Step in Time" from "Mary Poppins," but Robert's enthusiasm and excitement got the best of him and he started the number on the wrong foot. Working to correct his mistake only made it worse until partially through the number. After that, he was fine, but the judges were harsh, giving the pair a score of 24, 10 points lower than they received last week. I hope that the voting viewers know how hard he's trying and give them some support.
Pimlott blamed the scandal on poor leadership by "some bad apples" who have been removed from the academy, Most of the department's 7,000 employees were disgusted by the behavior, Pimlott said, adding that he has not seen any signs of extensive problems elsewhere within the agency, Among those punished were Justin Chaplin and Frank Schonig, They were demoted, and their pay was docked 5 percent for a year after officials said they cheated to get leadership positions at the academy, However, each regained their previous rank of captain in less than a month because ballet shoes number 5 birthday machine embroidery applique design-4x4,5x5,6x6 inch of the way the department wrote their disciplinary reports..
Mari Hulman George, 83. The "quiet pioneer" of auto racing who was instrumental in the expansion of Indianapolis Motor Speedway and became known to millions of fans over the years as the one who ordered countless drivers to start their engines before races. Nov. 3. Ramona Ripston, 91. A longtime activist who built up the American Civil Liberties Union of Southern California into a major organization. Nov. 3. Evelyn Y. Davis, 89. The brash shareholder activist who owned stock in more than 80 public companies and rarely failed to make her presence known at corporate-investor meetings. Nov. 4.
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