Today in Canada is the start of a long weekend. Across the country people will enjoy time off in celebration of Victoria Day. This is held annually on the Monday before May 24, in recognition of Queen Victoria's birthday.
My husband and I typically take advantage of what will hopefully be good weather on this weekend to get the gardens and yard in shape. Any time left is spent trying to fit as much good stuff in as possible.
We plan to kick off the three days slowly with a pizza date night on the deck following work Friday. Saturday will be yardwork and a trip to the nursery before our daughter arrives with her little girl in tow for a visit. There will be fun and games, followed by a campfire before bed.
Sunday includes a sojourn at the beach, while Monday will be finishing what we started working feverishly until late afternoon. At this point, we will hook up with the neighbours and try to slow down the clock, having realized that the first long weekend of summer is fading fast.
Of course, part of the fun of any weekend is knowing that plans can change in a minute. Unexpected guests drop by to take you away from chores; rain showers can put you behind or put a damper on anticipated excursions. But, as a person who at least likes to think they have all of their ducks in a row, there has to be some order. And so I plan.
Since I have given thought to how the next three days are supposed to go, it started me thinking about opportunities for taking some photos too. Inevitably, when a change of scenery happens, when family and friends gather, my camera is at the ready. It struck me, then, that with so many activities on the agenda it might be fun to create my own weekend photography challenge. Some will be straightforward, some will require a new way to look at an old subject. Then there are those that have been tricky in the past, which I can only hope to improve upon.
I also thought it might be fun to share my list so that others could take on my Victoria Day long weekend photo challenge too.
• Photos of gardens — Flowers are blooming, shrubs are greening. Fauna is crawling around and flying above. There are mama robins feeding their babies, bees hovering near dewy flowers. There is no end to the photo ops provided by nature.
• People at work — Hands in earth, and the sundry tools of yardwork can offer unique subjects.
• Campfires — The combination of flame and darkness is challenging, particularly as you try to capture the social vibe of this favourite summer pastime. It's not just about the fire, but also about the faces of the people around it.
* Fireworks — Capturing spectacular pyrotechnic displays that shine above others' efforts ups your game.
* A day at the beach — Any picture of sand and water is nice, but trying to take it to the next level is where the challenge lies. How can you go beyond what the eye sees?
* Time with friends — Catching the mood through candid photos of people you know well in a social setting can get some terrific results.
So there you have it. Should you choose to accept this challenge I hope you have fun with it. Either way, enjoy the weekend.


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Ad blocker usage is up 30% — and a popular method publishers use to thwart it isn't working
Ad blocker usage surged 30% in 2016, according to a new report from PageFair, a company that helps publishers regain revenue lost to the software.
There were 615 million devices blocking ads worldwide by the end of 2016, 62% (308 million) of those mobile. Desktop ad blocker usage grew 17% year-on-year to 236 million.
PageFair
The largest geographical driver of mobile ad blocker use has been in the Asia-Pacific, where 94% of mobile ad blocking takes place.
There hasn't yet been mass adoption of a mobile ad blocking app in North America or Europe yet, but PageFair predicts mobile ad blocking would accelerate in those regions if device manufacturers or distributors began to pre-configure ad blocking software as standard.
Security was the main reason cited for downloading an ad blocker among consumers polled in the US for the report. 30% of those surveyed said virus and malware concerns drove them to download an ad blocker.
The next most-cited reason for getting ad blocker software was "interruption" (29%), according to the report.
Dr Johnny Ryan, PageFair's head of ecosystem, said in the company's previous reports, privacy has been the primary motivation to downloading an ad blocker.
Ryan told Business Insider: "In 2014 we were dealing with early adopter users of ad blocking. These people really care and understand about the real problems of privacy and data leakage in ad tech. I think what happened is the industry's lack of an approach or interest in privacy let the ad block genie out of the bottle."
He continued: "But now [ad blocker usage] has grown to a broader demographic for whom [an ad blocker] is closer to just a remote control. The genie is out of the bottle and if the industry had taken privacy and data protection seriously this might not have happened."
PageFair's previous reports and those of different organizations found there was a significantly higher usage rate of ad blockers among males. While it's still true that more men use ad blockers than women, the report showed that the ad blocking demographics have broadened out beyond solely young techies:
The failure of ad block walls
The study also looked into how publishers are tacking the growing use of ad blocking software.
PageFair noted that 90% of ad blocker users surveyed have encountered an "ad block wall" that blocked them from viewing content unless they disabled their ad blocker.
However, almost three-quarters (74%) of those users said they simply left those websites rather than performing the steps required to whitelist them.
Ryan told Business Insider he wasn't surprised to see those sorts of figures.
He said: "It's very straightforward: There are not all that many publishers who have such exclusive content that they feel confident in establishing a paywall. By the same rationale, there cannot be that many publishers who have the confidence in establishing an ad block wall either. There are some publishers who claim, maybe rightly, 40% to 50% conversion ... [but there are] publishers who are turning away 50%, 60%, 70% of their traffic when they ask people to switch off their ad blocker. That's not sustainable for most the people we want to serve."
The alternative, Ryan says, is for publishers to listen to their audience about what's making them block ads, fix the problems, and serve them the solutions.
It's something Facebook did last year when it tweaked the technology to stop ad blocking software from working on its desktop website. The social network surveyed users, updated its ads preference tools to give users more control over the types of ads they were being served, then began circumventing the ad blockers because it believed it had created a better ad experience. On Facebook's Q3 earnings call, the company said desktop ad revenue grew 18% year-on-year in the quarter it began blocking the ad blockers.
PageFair has skin in the game here: It makes its money by helping publishers use technology to recoup money lost to ad blockers and find different ways to make revenue from those users. Often that's by using the Facebook method of serving ads — or an ad-light experience (77% of ad blocker users it surveyed said they found some ad formats permissible) — to ad blocker users. But Ryan made clear that if a publisher asks PageFair to help it set up an ad block wall, PageFair would oblige too.
The report ends with a fun factlet: "Adblock users are more educated." PageFair says 45% of ad blocker users it surveyed had attained a bachelor's degree or higher versus 30% across the US Census.
PageFair surveyed 4,626 users through a Google Consumer Survey. The company also used data from StatCounter, Internet Live Stats, eMarketer, and the US Census Bureau. You can read the full report here.
NOW WATCH: Ohio Rep. Tim Ryan is running for president — here's how mindfulness helps this top congressman stay calm in DC
Ad Blocking PageFair

redpajama_set_name: RedPajamaCommonCrawl


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Q: Using PyMySQL with MariaDB I have read this article about switching from MySQL to MariaDB on Ubuntu. The article claims that it would be not problem to switch between the two.
Currently, I am using PyMySQL to connect to my MySQL database and insert, update and delete values from it.
My question is: can I just upgrade to MariaDB and keep on using my Python code? Will PyMySQL also connect correctly to MariaDB?

A: As documented under MariaDB versus MySQL - Compatibility:

MariaDB is a binary drop in replacement for MySQL
For all practical purposes, MariaDB is a binary drop in replacement of the same MySQL version (for example MySQL 5.1 -> MariaDB 5.1, MariaDB 5.2 & MariaDB 5.3 are compatible. MySQL 5.5 is compatible with MariaDB 5.5 and also in practice with MariaDB 10.0). What this means is that:

*

*Data and table definition files (.frm) files are binary compatible.

*

*See note below for an incompatibility with views!

*All client APIs, protocols and structs are identical.

*All filenames, binaries, paths, ports, sockets, and etc... should be the same.

*All MySQL connectors (PHP, Perl, Python, Java, .NET, MyODBC, Ruby, MySQL C connector etc) work unchanged with MariaDB.

*

*There are some installation issues with PHP5 that you should be aware of (a bug in how the old PHP5 client checks library compatibility).

*The mysql-client package also works with MariaDB server.

*The shared client library is binary compatible with MySQL's client library.

  This means that for most cases, you can just uninstall MySQL and install MariaDB and you are good to go. (No need to convert any datafiles if you use same main version, like 5.1). You must however still run mysql_upgrade to finish the upgrade. This is needed to ensure that your mysql privilege and event tables are updated with the new fields MariaDB uses.

The article goes on to list a few minor incompatibilities, which you should check your application(s) do not rely upon.

redpajama_set_name: RedPajamaStackExchange


text:
Scientific term paper
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A character analysis of euripides ancient greece play the bacchae
Although several names and some fragments of poets who lived in the fourth century and in the Hellenistic era are known to modern-day scholars, intellectual and political developments, as well as the changing attitudes toward old gods and traditional religion, did not favor the kind of interpretation of the human past offered by tragedy.
It scours human mythology for various characters, items, and tropes; then throws them into barely recognizable, randomly generated quest-lines to keep things interesting for the players.
Caught at InterAct Theater in Philadelphia.
Directions in Euripidean Criticism: Loki is Odin's adopted son, rather than his blood brother, as he is in the myths. She has also done voiceovers for major feature films for Warner Bros and an independent feature film directed by Lee Grant.
Dionysos makes them think Pentheus is a deer, and they tear him to pieces with their bare hands and eat him compare the story of Actaeon. He has also driven the women of Thebes, including his aunts, into an ecstatic frenzy, sending them dancing and hunting on Mount Cithaeronmuch to the horror of their families.
At NJ Rep, Ms. Other recent New York City credits include: Further inland was the Illyrian Paeonian Kingdom and the tribe of the Agrianes. Was there a pattern of divine justice in these acts of revenge? Several theaters were built in many cities in the fourth century, including the greatest of Greek theaters, that of Epidaurus in northern Peloponnese.
There's a brief but oft-quoted speech in the inspirational sports movie Remember the Titans where the coach of the titular football team encourages his players to aspire to be like their mythical namesakes, who were "greater even than the gods".
It was first performed inand a recording was released in Pentheus makes the mistake of trying to deny and repudiate an entire realm of human experience. Along comes this stranger Dionysos in disguisedancing and singing and drinking wine.
This is well illustrated in the way that the Maenads are transformed from gentle beings who can manifest milk and honey from rocks and earth just by tapping them with their thyrsus, into possessed demons who take part in an orgy of death and dismemberment. Amora the Enchantress is based on Freya, who was indeed an enchantress, and very beautiful but she was never evil.
Pentheus intends to have him stoned to death. InDavid Greig wrote an adaptation of The Bacchae for the National Theatre of Scotland starring Alan Cumming as Dionysuswith ten soul-singing followers in place of the traditional Greek chorus.
In the original mythology Hades was actually the nicest god in the entire pantheon apart from Hestia. In Cardcaptor Sakura there's a scene of Eriol expressing the spirit of church hymns In the Light NovelsIsaac corrects Miria's notion that Frankenstein was the name of the monster instead of the doctor.
Instead, Agave spreads the lie that he is a mere mortal, born of a man and a woman. Admirably, instead of choosing a pagan god to turn into a demonthey used an actual evil spirit from Mesopotamian mythology as the one who possesses Regan.
Also, Set is a bit like Loki in that he was portrayed more as mischievous in early myths, only crossing over to "evil" after he became associated with certain foreign tribes known for perennially invading Egypt.The Bacchae: Theme Analysis, Free Study Guides and book notes including comprehensive chapter analysis, complete summary analysis, author biography information, character profiles, theme analysis, metaphor analysis, and top ten quotes on classic literature.
Greek tragedy, created in the city-state of Athens in the last thirty years of the sixth century B.C.E., is the earliest kind of European drama. Euripides' final masterpiece, the Bacchae, is uniquely centred on Dionysus, the god of the Athenian theatre as well as one of the most intriguing deities in the ancient Greek pantheon.
Throughout the play, which itself explains the establishment of Dionysus' cult in Greece, the tragedian includes many elements that were associated with the. OUTRAGE: NAFTA "renewal" forces year copyright extensions on Canadians -- your government talked big, but capitulated to the White House tyrant -- they had no mandate whatsoever for this giveaway But this is a battle we the people can win -- no provincial government publicly supports the deal.
The Bacchae study guide contains a biography of Euripides, literature essays, a complete e-text, quiz questions, major themes, characters, and a full summary and analysis. The Hellenistic period covers the period of Mediterranean history between the death of Alexander the Great in BC and the emergence of the Roman Empire as signified by the Battle of Actium in 31 BC and the subsequent conquest of Ptolemaic Egypt the following year.
The Ancient Greek word Hellas (Ἑλλάς, Ellás) is the original word for Greece, from which the word Hellenistic was derived.
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Q: Invariance of K-medoids clustering under distance measure Suppose we have n data points $X_1,X_2,...X_n$ where $X_i \in \mathbb{R^p}$ and we are performing k-medoids clustering to this dataset. Will the iterative (PAM) algorithm with identical initialization give the same cluster results between the choice of distance measure as sum of absolute distances or $L_1$ norm vs sum of squared distances or squared $L_2$ norm?
The assignment step will be identical between the two measures as points relatively close to chosen cluster medoid  in absolute distance will still be close in squared distance, but I am not very sure about the cluster medoid re-assignment step. I am trying to come up with a counterexample to demonstrate different results but unable to find anything. Would appreciate any help on this question.
If the question was for k-means instead of k-medoid, I believe the answer would be yes, the cluster results will be identical as distance measure is only used during the assignment step and any monotone transformation would preserve the ordering. Let me know if I am missing something here.

A: No, the assignment step can already differ.
Consider the means (0,0) and (5,2).
A point at (2,2) has L1 distances 4 resp. 3 and squared L2 distances 8 resp. 9. So it will be assigned to a different cluster. The nearest L1 is not the nearest L2.
Where the assignment would not make a difference is unsquared Euclidean vs. squared Euclidean. In that case, only the second step varies, 1d with a single far-out data point is enough to show this.


Join Dennis Taylor for an in-depth discussion in this video Getting exact table data with the VLOOKUP function, part of Excel 2016 Essential Training . Join Dennis Taylor for an in-depth discussion in this video Getting exact table data with the VLOOKUP function, part of Excel 2016 Essential Training. Lynda.com is now LinkedIn Learning! To access Lynda.com courses again, please join LinkedIn... How to use VLOOKUP in Excel 2016 In this tutorial, we�re going to show you how to use the VLOOKUP function in Excel . In this example, I have a list of people who have purchased Units, and a corresponding column of how many.
Tips � using range lookup in the Vlookup function in Excel.
A menu of all the applications on your computer will appear, scroll through the different applications until you see �Excel 2016�. Click it to open a new Excel document. Click it to open a new Excel document. how to correctly use instant read thermometer The VLOOKUP function is a powerful Microsoft Office tool and can be utilized for many applications. In this article, I give some basic instruction on how to use this function as a lookup/reference tool for displaying information.
How to Use the VLOOKUP Function in Microsoft Excel. The VLOOKUP function is used to pull a value from a list or table based on a corresponding value. For example, if you have a worksheet with a table showing employee names, hire date, and salary, you could use VLOOKUP in a separate worksheet to pull the hire date and salary for individual employees from the first worksheet. In this example how to use vlookup in excel 2010 step by step The VLOOKUP function is a powerful Microsoft Office tool and can be utilized for many applications. In this article, I give some basic instruction on how to use this function as a lookup/reference tool for displaying information.
For example, you can�t use Excel�s RAND function (which generates a random number) because VBA has an equivalent function: Rnd. VBA makes Excel�s worksheet functions available through the WorksheetFunction object, which is contained in the Application object.
Reverse Vlookup in Microsoft Excel If you are wondering how you can make Vlookup work backwards then this article is for you. In this article, we will learn how to use reverse Vlookup function without using INDEX & MATCH in Excel.


I am so excited to finally be sharing my new website & blog with you. This is one of those projects that takes so much time and collaboration that you just wonder if it will ever come together. And look! It has! And I'm wearing heels! (you know I never wear heels to work right?) But having a new website is a little like wearing heels. It feels like you do when you look your best. When you are in shape and the clothes are picked up off the floor.
We have new, professional images of our custom invitations. YAY! This has been something that I resisted in the past because of the cost but boy am I glad I finally just paid to have people who know what they are doing to take pictures of my invitations. It just dawned on me one day, the invitations are exquisite, stunning & unique, don't they deserve pictures that are worthy of them? They sure do! And now they exist. And man they look good!
You can now view our invitation options, pricing & ordering guide on the site. Before, I had to refer customers to an issuu album. It was working, kind of. It sure feels so good to have this all in one place now and I think my customers will agree.
I have a proper about page now with some more professional pictures taken that one day I wore heels. If you don't already know my story and how I got to where I am, I have given you more than you need to know on the about page. And if you don't care because you just love pretty stationery, skip it and look at the laser cuts again.
You can check all of our current retailers on the stores page and see if a store near you carries our products. This list has been updated since the old site since I have added more retailers.
You can now read what our customers have to say about working with Avie Designs on the reviews page. I blush a little just thinking about how kind they have been. They are way better at bragging about me than I could ever be and for that, I am truly grateful.
And last but not least, you can access the answers to most of your questions on the FAQ page (found under wedding). If you find that there is a burning question that you think should be added, please don't hesitate to let me know.
I am really excited to be back up and running with the new blog. I have lots of fun content coming up that I have been itching to share but have been waiting for the website to be completed. The focus is really going to shift. There is going to be the usual posts about what's going on with Avie Designs and our new products but there will also be new wedding and party related posts. This isn't going to turn into a wedding blog but I do want to give my customers some helpful resources.
If you haven't been over to the etsy shop in a while, you should check it out, we've made quite a few changes over there too.
Lastly, I need to thank a few people that helped make this site possible. I worked with Aeolidia and they were just a pleasure. Eva was my designer and Jon was my programmer. I can't thank them enough for all their help and patience. They were both lovely to work with. Erin & Bryan over at Tin Can Photography were also a big part of this website and it wouldn't have happened without them. Thanks!


Fribourg town centre. Set in an excluded position, this mansion features a large terrace and garden, the ideal spot in which to relax with friends while enjoying the stunning panoramic views.
layout that prioritises space and light. Surrounded by a laurel hedge and wrought-iron gate, the house enjoys a very private location. A large six- car garage completes this magnificent property.


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\section{Introduction}

Since lately Wikipedias have been a vibrant interdisciplinary field of study ~\cite{Voss,NasWiki,Capocci,Muchnik,Huberman,Mehler,Giles}. The unique character of the free editing article policy and the large number of people participating in the process, make Wikipedia excellent model system for investigation of some complex system ideas in a realistic environment of the real social structure. Indeed, in the last few years there has appeared a growing amount of evidence supporting the usage of ideas from statistical physics, graph theory etc. in the description of the social or economic phenomena. This especially applies to phenomena which previously seemed untouchable from the natural scientists point of view~\cite{Palla,BarabasiQue,CaldaBanks}.

One of the very interesting features previously observed in Wikipedias is their reciprocity~\cite{NasWiki}. Reciprocal arcs are just the arcs pointing from the vertex $i$ to the vertex $j$ for which exists an arc pointing from vertex $j$ to the vertex $i$. The reciprocity is then defined as the fraction of reciprocal arcs in the total number of arcs $r=\frac{L^{\leftrightarrow}}{L}$~\cite{Reciprocity}. It was previously shown that reciprocal arcs can have an interesting role in real networks and in the theory describing them~\cite{WWW,Boguna,Zhou}. It also seems to be the most stable network measure one can find in the ensemble of Wikipedias except possibly the in-degree distribution exponent~\cite{NasWiki}. In~\cite{Gorka}, it was also shown that the reciprocity of Wikipedias cannot be explained by random mixing of arcs. In this paper we show in which manner reciprocal arcs influence the observed Wikipedia structure and show that they represent the necessary ingredient for understanding the Wikipedia growth and organization.

\section{Reciprocity in Wikipedia}

In order to understand how reciprocal arcs affect the structure of Wikipedia, first we need to examine if they exhibit any peculiar behavior at all.
 In the case of Wikipedia, one can expect existence of the reciprocal arcs between articles that share certain portion of content.
 If that were true, then the first assumption should be that the reciprocal arcs are distributed over the underlying Wikipedia network corresponding to mutual similarity of different articles.
 In other words, the content similarity of two articles is supposed to be independent of degrees of those two articles. One way to study this independence is laid out in the companion paper~\cite{NasTeorija}.
 There we show that the independence of reciprocal arcs can be studied using the the inverse matrix of the process of random addition of reciprocal arcs. Particularly we can use the equation
\abovedisplayskip=5 pt
\begin{equation}\label{JednadzbaInvTrans}
\langle \mathbf{S}(0)\rangle=\mathbf{T}_{1v}^{-1}(p)\mathbf{S}'(p),
\end{equation}
\belowdisplayskip=5 pt
to study such a process. In Eq. (\ref{JednadzbaInvTrans}) $\mathbf{S}'(p)$ represents the vector of product moments of degrees observed in the real network, $p=\frac{L^{\leftrightarrow}}{2L}$ represents the fraction of unidirectional arcs that were transformed to bidirectional, $\mathbf{T}_{1v}^{-1}$ is the inverse of the transformation matrix and $\langle \mathbf{S}(0)\rangle$ represents the expected vector of product moments of degrees in the network without reciprocal arcs. In Fig.~\ref{KiKrVsp.eps} we show that some types of correlations indicate that the assumption of the degree independent reciprocal arcs can not be justified in Wikipedia networks. It is obvious than the parameter $p$ can not be larger then $\sim0.07$ and from the data we know that the parameter $p$ should be around $\sim 0.16$.

\begin{figure}[t]
\centering
\includegraphics*[width=0.5\textwidth]{KiKrVsp.eps}
\caption{\label{KiKrVsp.eps} The change of expected initial correlations of onevertex degrees $\langle k_ik_r \rangle$ calculated from the inverse of transformation matrix $\mathbf{T}^{-1}_{1v}$ for three different Wikipedias. Expected values of monitored correlations are changing the sign for the value of parameter about $p\sim 0.07$. Since the product moment correlations are strictly positive, this behavior indicates that there is just a small fraction of reciprocal arcs which are degree independent. In the case of Wikipedias the maximal value of parameter $p$ is about $p\sim 0.16$. }
\end{figure}

This analysis is based on a very strong assumption of network stationarity. We know that the Wikipedia networks grow as many different Wikipedians edit many articles. Clearly it is necessary to investigate the influence of reciprocal arcs on the growth of Wikipedia.
In~\cite{NasWiki} we showed that different Wikipedias grow in a very similar fashion and that the number of newly added arcs is not linear with respect to the number of vertices. Nevertheless the observed behavior $L\sim N^{1.14}$ is close enough to linear that we can approximate it by a linear growth.

\section{Model}

The model we use to describe the growth of Wikipedias is studied in detail in ~\cite{NasTeorija} and we just summarize the idea of the model and list the most important analytical results.
 The studied model was inspired by our findings in the Wikipedia networks~\cite{NasWiki}.
 Other authors studied the growth of Wikipedia networks with focus on preferential attachment~\cite{Capocci} and they found a linear-like relationship between the in--degree of the vertex and its probability to acquire a new arc, at least for the small and medium vertex degrees.
 It is also known that there is a significant portion of new arcs forming between old vertices in the network.
 Nevertheless this very often happens between vertices which are ``young'' compared to the age of the network~\cite{Personal}.
 This leads us to believe that ignoring additional formation of arcs betwen the older vertices is a reasonable approximation for the growth of the Wikipedia-like network.

The model consists of two steps. In the first one a new vertex, introduced in the network at time $t$ and therefore labeled as $t$, attaches to the network with $m$ outgoing arcs. The probability that the given arc, from these $m$ arcs, will attach itself to some vertex $s<t$ is proportional to the in--degree $k_i(s)$ of the vertex $s$. In the second step for every new arc with the probability $r$ a new reciprocal arc is formed between vertices $s$ and $t$. We showed that for such a model it is possible to find exact joint degrees probability distribution $P(k_i,k_o)$ of a single vertex. For example, in the case $m=1$, the distribution has the form
\begin{widetext}
\begin{equation}\label{konacnom1}
P(k_i,k_o)=\Theta(k_i-k_o)\binom{k_i-1}{k_o-1}r^{k_o-1}(1-r)^{k_i-k_o}\frac{r(1+r)}{2+r}\frac{(k_i-1)!}{(r+3)_{k_i-1}},
\end{equation}
\end{widetext}
 where $\Theta(x)$ is a usual Heaveside function and $(r+3)_{k_i-1}$ represents Pochammer symbol~\cite{Wolfram}. The asymptotic behavior of the marginal in-degree distribution for the described model is of the form:
\begin{equation}\label{KontRjesP(k_i)m1}
 P(k_i)\sim k_i^{-(2+r)}.
\end{equation}
This solution nicely interpolates between directed and undirected cases of the BA model~\cite{Usmjereni BA,BAJ99}. Furthermore, the asymptotic behavior of the in-degree distribution given in (\ref{KontRjesP(k_i)m1}) is also valid for any $m$, i.e. the power-law exponent does not depend on $m$.
 In~\cite{NasWiki} we reported the exponent of the in-degree distribution around $\gamma\simeq 2.18$  and values of reciprocity coefficient around $r_e\simeq0.35$.
The described model for $m=1$ predicts the relations $r_e=2r/(1+r)$ and $\gamma = 2+r$, which explain the observed empirical values of $r_e$ and $\gamma$.

The three parameters which define the model are: $t$ - the size of the modeled network, $m$ - the number of outgoing arcs of the new vertex and $r$ - the probability of accompanying new arcs with their reciprocal arcs.
 In order to validate the model, we fixed three measured parameters of Wikipedia networks which uniquely describe the degree distributions obtained in the model.
 First the number of vertices in the monitored Wikipedia must be the same as the final size of the model network i.e. $t_{model}=N_{Wikipedia}$.
 In this way it is possible to check if the model also captures the details of the distribution in the tail as well as the power law exponent.
 The second parameter is the number of arcs in the modeled Wikipedia.
The expected number of arcs obtained in the ensemble of model realizations has to be the same as the number of arcs measured in the modeled Wikipedia i.e. $E(L_{model})=L_{Wikipedia}$. The third parameter is the number of reciprocal arcs $L^{\leftrightarrow}_{Wikipedia}=E(L^{\leftrightarrow})$.
 The last two empirical parameters depend on our model parameters as
\begin{equation}\label{ExpNumbEdge}
L_{Wikipedia}=E(L_{model})=tm(1+r),
\end{equation}
and
\begin{equation}
 \label{expNumbRec}
L^{\leftrightarrow}_{Wikipedia}=E(L^{\leftrightarrow})=2tmr.
\end{equation}
From these equations it is easy to express our model parameters as functions of measured quantities:
\begin{equation}
 \label{mForWiki}
m=\frac{L_{Wikipedia}-\frac{L^{\leftrightarrow}_{Wikipedia}}{2}}{N_{Wikipedia}},
\end{equation}
and
\begin{equation}
 \label{rForWiki}
r=\frac{L^{\leftrightarrow}_{Wikipedia}}{2L_{Wikipedia}-L^{\leftrightarrow}_{Wikipedia}}.
\end{equation}
\indent The parameter $m$ obtained from the measured quantities is not necessarily a natural number, which is supposed in our analytical treatment~\cite{NasTeorija}. In order to overcome this inconvenience we have used random numbers $\mathbf{m}$ drawn from Poisson distribution $E(\mathbf{m})=m$, to be the value of $m$ at any given time. We have shown that such a distribution has properties almost identical to our model with $m$ as a natural number if a suitable $E(\mathbf{m})$ is chosen~\cite{NasTeorija}.

\section{Results}

In Fig. \ref{Fig: ModelVsWiki} we show an excellent agreement between the in-degree distribution of Japanese Wikipedia and our model.
 It is clear that the mode of the distribution is also well described with our model, a feature not so common in other degree distribution models found in the literature.
 We have already mentioned that in~\cite{Capocci} small and medium degrees show a kind of preferential attachment.
 For this reason it is important that our model describes well the mode which is formed by the vertices of relatively small in-degree.
 The tail of the distribution is also very well described by our model. This is important because such a tail was found to be a universal feature of Wikipedias in different languages.

If we compare a cumulative in-degree distribution of the model to the one of Wikipedias (see Fig. \ref{Fig: EnInModel}), it is again easy to see that our model shows a very good agreement in the tail of the distribution.
 One can also notice that our model shows a deviation from the monitored Wikipedia in the very end of the distribution.
 It is not surprising because we have already confirmed that the linearity in the attachment principle was observed only for small and medium degrees.
 The largest degrees show the ``aging'' effect i.e. they rarely attract new arcs, because their neighborhood is already matured in its content.
 We did not model such a behavior in order to keep the model as simple as possible.

\begin{figure}[t]
\centering
\includegraphics*[width=0.5\textwidth]{japoneseVsModel1Real2.eps}
\caption{\label{Fig: ModelVsWiki} Comparison of the in-degree distribution of the Japanese Wikipedia with one realization of our model for given parameters. It is easy to see excellent agreement both between mode of distribution, and exponent (slope in the log-log). Chosen parameters are $t=94094$, $m=16.75$, $r=0.18$. Our simulations show very similar behavior for the rest of studied Wikipedias. }
\end{figure}

\begin{figure}[t]
\centering
\includegraphics*[width=0.5\textwidth]{EnInCumVsMod.eps}
\caption{\label{Fig: EnInModel} Comparison between cumulative in-degree distribution of English Wikipedia (blue circles) with one realization of our model (red line). Chosen parameters are $t=486291$, $m=18.24$, $r=0.15$. The distribution of the model follows closely the distribution of the model except in the very end of the tail, where we expect the aging effects in the real network.}
\end{figure}

Our model does not reproduce out-degree distribution well (see Fig. \ref{Fig: OutPrefRecip}). The mode of the modeled distribution is shifted to much to the right and it is too narrow in comparison to the realistic out-degree distributions. This could be the consequence of using Poisson distribution for parameter $\mathbf{m}$, which is too narrow in this case. The reason we chose it is just because it is the most easily justifiable one parameter distribution for that case. Clearly we could get much better result with broader modal distributions for the parameter $\mathbf{m}$, but such a choice would be hard to justify and would be introduced just for fitting purposes. Since the aim of this paper is to clarify the fundamental role of the reciprocal arcs in the structure and growth of Wikipedia network, we focus on the version of the model which requires no fitting procedures.
\begin{figure}[t]
\centering
\includegraphics*[width=0.5\textwidth]{JaOutRecip.eps}
\caption{\label{Fig: OutPrefRecip} Comparison between out-degree distribution of Japanese Wikipedia (blue circles) to one realization of our model (red squares). Chosen parameters are $t=94094$, $m=16.75$, $r=0.18$. There is no similarity between the modes of two distributions, and the slope of the tails seem to coincide in the very end of the distribution. }
\end{figure}

\section{Conclusion}

An excellent agreement of the Wikipedia and model in-degree distribution confirm that our model is a natural continuation of the process of preferential attachment, at least for the process of Wikipedia growth.
 Would the inclusion of the additional formation of new arcs between old vertices improve the agreement is discutable.
 The heuristics for additional changes in the model is not easy to justify without additional exploration of Wikipedia networks.

It can be asserted that presented logic of Wikipedia growth can be attributed to the Wikipedians who are editing both old and new articles in a very small time frame.
 In such a case the reciprocity is also a good measure of the information interrelatedness in the knowledge networks.
 Clearly, the existence of the reciprocal arcs point to a certain intersection of the sets of information presented in different articles.
 Since reciprocity represents only the first viable correlation for such information sharing, it can be asserted that even better results could be expected if the model would take care of conservation of similar measures such as triad significance profile~\cite{Milo} or some other local structural motives.
 Taking into account the neighborhood of articles as a pool of more probable information sharing could also improve quality of the model.
 Problem with such attempts is the increase in the number of parameters which such models would require.

The usefulness of our model in the case of networks of different origin is presently not clear.
 We feel that we have demonstrated a significant value of this model for understanding of Wikipedia networks and we believe that it could also be important in the case of other types of knowledge networks with time-dependent formation of arcs.
 Since reciprocity is a natural representation of feedback, the presented model and its extensions could aslo be useful in the study of complex systems in which feedback play an important role.
The effort in this direction is a logical continuation of this research.

\section{Acknowledgments}

This work was financed by the Ministry of Education, Science and Sports of the Republic of Croatia under the contract No. 098-0352828-2863 and by the INFN, Italy. Vinko Zlati\'c is thankfull for support of G. Caldarelli and would like to thank A. Gabrielli for reading the manuscript.

redpajama_set_name: RedPajamaArXiv


Research proposal formats may vary from each other depending on the factors like magnitude of proposed research and complexity of the procedure. The size of the research proposal should be concise and in continuation that should include all aspects of a research paper (McNiff & Whitehead 2009).
The Research Proposal Submission Form is provided by the Provost and Vice President for Academic Affairs. Please note the faculty member's department head and dean must sign the checklist included with the summary information, indicating the support the department or college can give to the proposed research project. .
A good deal of investigation needs to be conducted in the specific locale where the project being researched on will be conducted. And if all your facts are accounted for, and all your ideas organized, you face the final hurdle of translating everything into a paper in the proper research proposal format, clear, relevant, practical and impressive enough to catch and hold the attention of the people who will be funding it.You can Download the Free Research Proposal Template form, customize it according to your needs and Print. Research Proposal Template is either in MS Word and Editable PDF.
You can Download the Free Research Proposal Template form, customize it according to your needs and Print. Research Proposal Template is either in MS Word and Editable PDF.
Though you have probably already spent some time learning how to write a thesis sentence, this is actually not what you want to do with your research proposal. Remember, you are not setting out to conduct research in order to prove a point. When discussing the topic, you must be fair, balanced, and open-minded. You must leave room in this part of the research proposal for flexibility.


text:
This can be a tricky topic because our adult minds often associate consent directly with sexual expression. But for children it's about so much more. Teaching children to understand consent from an early age allows them to develop language skills, boundaries, self-confidence, respect, empathy, autonomy, AND it significantly reduces the risks of potential abuse.
You can introduce the idea of consent by role playing with your child. Ask them if they want a hug. If they say yes, then give them a hug. If they say no, say, "Ok, you make the rules about your body so I will not hug you."
You can introduce this idea with family and friends as well. It's really important never to force children into physical interactions, or allow others to do so. For example, when Granny comes to visit, say out loud, "We are learning about consent this week. Would you like to give Granny a hug? No? That's ok, what about a high five instead? Also not? Ok, we can just use words to greet today. Hi Granny!"
Unfortunately, statistics show that perpetrators of abuse are rarely strangers, but rather within the family circle. Teach your child that if they ever feel uncomfortable about being touched, or are asked to do something that feels wrong to them, it's important that they tell an adult whom they trust. If that adult won't listen or doesn't believe them, they should keep telling more adults until someone listens.
Even if your child is particularly self-assured and independent, all children can struggle when faced with a novel situation. Role play is a really effective way to teach children how to behave when they may feel otherwise feel uncomfortable and helpless. Role play gives them an opportunity to practice words and actions in a safe space, which prepares and empowers them for the future. It also speaks to them on a developmentally appropriate level, since children naturally love to immerse themselves in imaginative scenarios.
Think of as many scenarios that you can think of in which consent would be important. For example:
Your uncle wants to play a tickle game but you don't want to.
Granny wants to give you a kiss.
You want to hug your friend but they say no.
Your cousin wants to wrestle, but just as you start enjoying it, they want to stop.
You said you were happy to share your teddy but changed your mind.
Write each on a slip of paper and then ask your child to pick one at a time. You can take turns at playing each role in the relationship. Carefully note when your child feels uncomfortable and if need be, provide them with a script. "No, Uncle, stop! Stop tickling me!" Allow them to practice this script and encourage the use of loud voices and that stop means stop, no questions asked. "My angel, Suzie said that she doesn't want a hug right now, so you cannot hug her. Suzie's body; Suzie's rules."
This may seem like overkill, and some friends and family may even be offended in the process. But your child's safety is more important than appeasing others.
Clare Emms
Jess Prinsloo
Rida Viljoen
Jessica Prinsloo
Megs Holliday
Rida Viljoen


We have worked in the residential, commercial and industrial fields and have lots of experience in handling sensitive sites such as Hospitals, Airports, Schools & Banks etc. We have the inventory and manpower needed to get the job done in accordance with your construction schedule. We have never been removed from a project for non performance.
If you are unsure that we can help or think we might be able to, always feel free to call and inquire.
Arwood Waste. is a family owned and operated company inDuval, DeLand Florida, that has been in business for over 20 years. Our management staff has over 65 years of combined experience in the demolition & construction field.
We handle most facets of the demolition industry which include: Interior / exterior demolition, structural demolition, concrete cutting, core drilling, flooring removal etc. We have worked in the residential, commercial and industrial fields and have lots of experience in handling sensitive sites such as Hospitals, Airports, Schools & Banks etc. We have the inventory and manpower needed to get the job done in accordance with your construction schedule. We have never been removed from a project for non performance.
We place safety high on our list and take pride in the fact we have never been fined by OSHA in all the years we have been in business. We have our own in house safety program which includes a certified OSHA outreach trainer, and all of our supervisors have the 10 hour OSHA course at minimum with some also having the 30 hour course if required for a specific job. We spend a great deal of time training our own people to become successful and experienced demolition workers. We do NOT use day labor staffing as we feel that we can put forth a better product by training and managing our own staff in house.
Communication is also a key part of our company's success. All of our staff at every level, speak English and do their paperwork on a daily basis. We are reachable by phone, fax or email and there is always someone that can be contacted at all hours when it comes to managing our work.
We have certified on staff instructors and we are capable of pulling permits if required. We are MWBE / DBE and an emergency res-ponder for Duval, Volusia & Flagler counties. We have several 40 hours Asbestos Supervisors on staff in order to handle some of the limited Asbestos abatement (wet demo) that we perform in house.
We recycle materials at every opportunity in order to make the world a greener place and to keep job costs down. We pride ourselves in being a team player and work hand in hand with other subs on the job to keep it a safe and productive site.
We service Duval, Volusia, Flagler, Seminole, Orange, Osceola, Brevard, Lake, Clay, St. John's & Putnam counties but will take on jobs further out from our base area if they are big enough to consider and if we feel that we can be competitive for that bid. All of our estimates are free of charge..
Hydraulic excavators may be used to topple one- or two-story buildings by an undermining process. The strategy is to undermine the building while controlling the manner and direction in which it falls. The demolition project manager/supervisor will determine where undermining is necessary so that a building is pulled in the desired manner and direction. The walls are typically undermined at a building's base, but this is not always the case if the building design dictates otherwise. Safety and cleanup considerations are also taken into account in determining how the building is undermined and ultimately demolished. Hoe rams are typically used for removing the concrete road deck and piers during bridge demolition, while hydraulic shears are used to remove the bridge's structural steel.
High reach demolition excavators are more often used for tall buildings where explosive demolition is not appropriate or possible. Excavators with shear attachments are typically used to dismantle steel structural elements. Hydraulic hammers are often used for concrete structures and concrete processing attachments are used to crush concrete to a manageable size, and to remove reinforcing steel.
Loaders or bulldozers may also be used to demolish a building. They are typically equipped with "rakes" (thick pieces of steel that could be an I-beam or tube) that are used to ram building walls. Skid loaders and loaders will also be used to take materials out and sort steel.
It takes several weeks or months to prepare a building for implosion. All items of value, such as copper wiring, are stripped from a building. Some materials must be removed, such as glass that can form deadly projectiles, and insulation that can scatter over a wide area. Non-load bearing partitions and drywall are removed. Selected columns on floors where explosives will be set are drilled and high explosives such as nitroglycerin, TNT or C4 are placed in the holes. Smaller columns and walls are wrapped in detonating cord. The goal is to use as little explosive as possible; only a few floors are rigged with explosives, so that it is safer (fewer explosives) and less costly. The areas with explosives are covered in thick geotextile fabric and fencing to absorb flying debris. Far more time-consuming than the demolition itself is the clean-up of the site, as the debris is loaded into trucks and hauled away.
A new approach to demolition is the deconstruction of a building with the goal of minimizing the amount of materials going to landfills. This "green" approach is applied by removing the materials by type material and segregating them for reuse or recycling. With proper planning this approach has resulted in landfill diversion rates that exceed 90% of an entire building and its contents in some cases. In addition, it also vastly reduces the CO2 emissions of the removing of a building in comparison to demolition.
Jump up^ "HD_20h_20070822_chunk_2 – Vidéo Dailymotion". Dailymotion.com. 23 August 2007. Retrieved 2012-05-06.
Jump up^ "Kajima Demolition Tech". Popular Science. December 2008. Retrieved 2008-11-18.
Jump up^ Cultice, Curtice (1997). "Blasting a path to world markets". BNET Business Network. Retrieved 2008-05-19.
Jump up^ Bohart, Maura (26 September 2007). "Demolition Eliminates Final Remnant of Charlotte Hornets". Construction Equipment Guide. Retrieved 2008-05-19.
Jump up^ "J.L. Hudson Department Store". Controlled Demolition, Inc.
From Florida to Washington state, more people are choosing to "deconstruct" their homes and other buildings.
Deconstruction is the practice of carefully disassembling a building so that its materials — everything from siding to floor joists — can be reused in a new building, while everything else that can be recycled is recycled.
Around 270,000 homes are torn down annually in the U.S., and most of the debris goes to dumps or landfills, Falk says, citing statistics from the Environmental Protection Agency. That's a staggering 1 billion board-feet of timber alone going to the dump — enough to make tens of thousands of homes, he says.
Here's another way to look at it: Just one year's demolition debris is enough to build a wall 30 feet high and 30 feet wide around the entire border of the continental United States, according to theDeconstruction Institute.
Salvaging from old structures to build new ones is hardly new; stone from Rome's Colosseum was plundered to help build St. Peter's Basilica, and salvage stores have been around for decades. But the idea has gotten new wind under its wings in the past several years, as more people care about doing right by the environment — and more governments are watching their landfills fill up. Homeowners are finding that it often pencils out, too.
Today, Falk estimates that nationwide there are 1,500 deconstruction contractors and "reuse" stores like those run by Habitat for Humanity, which sell the recycled doors, windows and fixtures.
When a home is demolished, all it takes is two people and perhaps a day or two: One person operates a track hoe while the other drives the debris away in a dump truck.
When a home is deconstructed, on the other hand, a crew of perhaps six workers descends on the house for a week or more. They carefully peel the house apart. What's saved? "Just about everything except the drywall and plaster," says Paul Hughes, founder and president ofDeConstruction Services in Fairfax, Va.
Items such as appliances, cabinetry and wood flooring can be reused, Hughes says.
People might be surprised by what's recycled: Asphalt roof shingles can be "crumbed" and mixed with other materials to make road patches. Broken lumber pieces can be ground up and used as wood chips for trails or for mulch. Cinder blocks can be pulverized and used as the base for roads or driveways, or as backfill for other structures, Hughes says.
People also might be surprised at the time it takes. "The first home I took down took 3½ weeks. Now I could easily take that same building down in 3½ days. We've gotten way better," says Dave Bennink, the owner of Bellingham, Wash.-based Re-Use Consulting, which has deconstructed about 550 buildings.
Worried about the environment and about their landfills filling up, cities have encouraged the trend. In Seattle, where a demolition permit is mandatory before razing a house — and where that permit can take weeks to acquire — the city gives an incentive to deconstructors by putting their applications on "the top of the pile" and reducing their wait time, Bennink says.
In San Jose, Calif., the city collects a deposit to ensure that demolition debris stays out of the landfill; a homeowner must prove he has diverted the waste in order to get his money back.
Bennink, who consults around the nation, says he is seeing more interest in deconstruction in Rust Belt cities in the Midwest and Northeast — cities such as Detroit, Buffalo, N.Y., and Youngstown, Ohio — that have both a stock of older, often vacant houses and a crop of unemployed people who need retraining. The deconstruction trade has gotten a big boost from federal stimulus spending, he says, in the form of programs to teach people how to take apart homes.
"There are as many social benefits to doing this as environmental benefits," Bennink says. Remember that home demolition that required only two people? With deconstruction, he says, "We're creating 25 times more jobs than demolition" — a figure Bennink says is based on an analysis he has done. It's not just guys swinging hammers at the job site, but "green-collar jobs" in the reuse stores, in wood shops reconditioning the salvaged wood — even in shops creating furniture from the salvaged material, he says.
Demolition Dumpster Rentals? Arwood Waste Now Services The Entire United States!
Keeping your construction site clean through out America and free of debris is good for safety, appearances and helps keep up worker morale. Plus, a trashy work site can make it hard to keep your project organized and on-track. Our Roll-Off dumpsters are great for construction and demolition sites as well as smaller projects like residential remodeling.


text:
Tag: Watch Dogs
Watch Dogs Single Player DLC Drops on All Platforms
Today Ubisoft released new Watch Dogs single player DLC content for all available platforms including Xbox 360, Xbox One, PS4, PS3 and PC. The Wii U version of Watch Dogs has yet to be released. The new Watch Dogs DLC includes three single player… Read More
NBA 2K14 PS4 and Xbox One Screenshots Scream Next-Gen
With an 'OMG' trailer and handful of sexy screenshots, 2K's NBA 2K14 for Xbox One and PS4 has emerged as one of the must-own next-gen launch titles for the new consoles from Microsoft and Sony, respectively. Yesterday 2K… Read More
NBA 2K14 PS4 Trailer Wants You to Scream OMG
2K Sports has delivered the first NBA 2K14 PS4 trailer that was first hinted at when a still of LeBron James snapped from the game was released. The trailer is titled 'OMG' and for good reason. James, Kevin Durant, and James Harden's… Read More
Watch Dogs Delayed by Ubisoft on All Platforms to Spring 2014
Ubisoft's ambitious Watch Dogs game has been widely considered to be one of the top Xbox One and PlayStation 4 launch titles since it was first unveiled. Unfortunately, Watch Dogs is a next-gen launch title no more. Ubisoft posted a Watch… Read More
Sony Gamescom 2013 Press Conference: Watch Live Online Streaming Here
Millions of eyeballs will be plastered on Sony's Gamescom 2013 Press Conference in hopes that the PlayStation 4 release date will finally be unveiled, and the event will be live streamed over the Internet for free. The start time for… Read More
PS4 Bundles Pre-Orders in Stock at Amazon and Launch Day Guaranteed
Sony PS4 bundles pre-orders guaranteed for launch day have returned and are back in stock at online retailer Amazon.com. If history repeats itself these won't last long, so if you missed out on the first batch, you better pre-order your… Read More
PS4 and Xbox One Pre-Orders Set Impressive Sales Record at Amazon
Online retailer Amazon.com has announced PS4 and Xbox One pre-orders have set a record for the store's biggest pre-order week in video games ever. During the week of E3 when Amazon begun taking pre-orders of Xbox One and PS4 consoles,… Read More
Xbox One Game Pre-Orders Lay Siege to PS4 Games on Amazon's Movers and Shakers
Microsoft laid down the gauntlet in the next generation console wars when it bent to fan demand, a move made more necessary by Sony's unrestrictive policies boasted at E3, to remove DRM restrictions and allow for used games sales on Xbox… Read More
Watch Dogs PS4 Bundle Pre-Order Leading the Amazon Pack
The stellar Watch Dogs PS4 bundle pre-order performance at Amazon is proving Ubisoft has developed a knack for offering the must-own game for a new console launch. Having seen the E3 demo in person, the sustained interest in the story of a hacker… Read More
PS4 Pre-Orders Soaring as Amazon Bundles Now Only Launch Day Guarantee
Sony continues to ride the aftershock of an impressive E3 showing that resulted in a standing ovation as PS4 pre-orders remain strong 10 days after retailers first made them available. Sustained interested in PS4 and steady sales raises questions… Read More


text:
from __future__ import print_function
# Authors: Denis Engemann <denis.engemann@gmail.com>
#
# License: BSD (3-clause)

import os
import os.path as op
from functools import reduce

import numpy as np
from numpy.testing import (assert_array_almost_equal, assert_array_equal,
                           assert_allclose)
from nose.tools import assert_true, assert_raises, assert_equal

from mne.io import Raw as Raw
from mne.io.bti.bti import (_read_config, _setup_head_shape,
                            _read_data, _read_bti_header)
from mne.io import read_raw_bti
from mne import concatenate_raws

base_dir = op.join(op.abspath(op.dirname(__file__)), 'data')

archs = 'linux', 'solaris'
pdf_fnames = [op.join(base_dir, 'test_pdf_%s' % a) for a in archs]
config_fnames = [op.join(base_dir, 'test_config_%s' % a) for a in archs]
hs_fnames = [op.join(base_dir, 'test_hs_%s' % a) for a in archs]
exported_fnames = [op.join(base_dir, 'exported4D_%s_raw.fif' % a)
                   for a in archs]
tmp_raw_fname = op.join(base_dir, 'tmp_raw.fif')

# the 4D exporter doesn't export all channels, so we confine our comparison
NCH = 248

def test_read_config():
    """ Test read bti config file """
    # for config in config_fname, config_solaris_fname:
    for config in config_fnames:
        cfg = _read_config(config)
        assert_true(all('unknown' not in block.lower() and block != ''
                        for block in cfg['user_blocks']))

def test_read_pdf():
    """ Test read bti PDF file """
    for pdf, config in zip(pdf_fnames, config_fnames):
        info = _read_bti_header(pdf, config)
        data = _read_data(info)
        shape = (info['total_chans'], info['total_slices'])
        assert_true(data.shape == shape)

def test_crop_append():
    """ Test crop and append raw """
    raw = read_raw_bti(pdf_fnames[0], config_fnames[0], hs_fnames[0])
    raw.preload_data()  # currently does nothing
    y, t = raw[:]
    t0, t1 = 0.25 * t[-1], 0.75 * t[-1]
    mask = (t0 <= t) * (t <= t1)
    raw_ = raw.crop(t0, t1)
    y_, _ = raw_[:]
    assert_true(y_.shape[1] == mask.sum())
    assert_true(y_.shape[0] == y.shape[0])

    raw2 = raw.copy()
    assert_raises(RuntimeError, raw.append, raw2, preload=False)
    raw.append(raw2)
    assert_allclose(np.tile(raw2[:, :][0], (1, 2)), raw[:, :][0])

def test_raw():
    """ Test bti conversion to Raw object """

    for pdf, config, hs, exported in zip(pdf_fnames, config_fnames, hs_fnames,
                                         exported_fnames):
        # rx = 2 if 'linux' in pdf else 0
        assert_raises(ValueError, read_raw_bti, pdf, 'eggs')
        assert_raises(ValueError, read_raw_bti, pdf, config, 'spam')
        if op.exists(tmp_raw_fname):
            os.remove(tmp_raw_fname)
        with Raw(exported, preload=True) as ex:
            with read_raw_bti(pdf, config, hs) as ra:
                assert_true('RawBTi' in repr(ra))
                assert_equal(ex.ch_names[:NCH], ra.ch_names[:NCH])
                assert_array_almost_equal(ex.info['dev_head_t']['trans'],
                                          ra.info['dev_head_t']['trans'], 7)
                dig1, dig2 = [np.array([d['r'] for d in r_.info['dig']])
                              for r_ in (ra, ex)]
                assert_array_equal(dig1, dig2)

                coil1, coil2 = [np.concatenate([d['coil_trans'].flatten()
                                for d in r_.info['chs'][:NCH]])
                                for r_ in (ra, ex)]
                assert_array_almost_equal(coil1, coil2, 7)

                loc1, loc2 = [np.concatenate([d['loc'].flatten()
                              for d in r_.info['chs'][:NCH]])
                              for r_ in (ra, ex)]
                assert_array_equal(loc1, loc2)

                assert_array_equal(ra._data[:NCH], ex._data[:NCH])
                assert_array_equal(ra._cals[:NCH], ex._cals[:NCH])
                # Make sure concatenation works
                raw_concat = concatenate_raws([ra.copy(), ra])
                assert_equal(raw_concat.n_times, 2 * ra.n_times)

                ra.save(tmp_raw_fname)
            with Raw(tmp_raw_fname) as r:
                print(r)
        os.remove(tmp_raw_fname)

def test_setup_headshape():
    """ Test reading bti headshape """
    for hs in hs_fnames:
        dig, t = _setup_head_shape(hs)
        expected = set(['kind', 'ident', 'r'])
        found = set(reduce(lambda x, y: list(x) + list(y),
                           [d.keys() for d in dig]))
        assert_true(not expected - found)

redpajama_set_name: RedPajamaGithub


grandma's cookie jar: I Have Two Winners . . .
I'm happy to announce Kathy Williams and Wanda Wilson are the winners in my second-chance Boca Java tea give-away! (You'll find the review at this link) Thank you Kathy and Wanda for reading grandma's cookie jar and thank you Boca Java for sending tea for me to review and for making additional tea available for me to give away!


text:
Pfizer and its partner BioNTech will apply on Friday for emergency authorisation in the US for their Covid-19 vaccine.
It will be the job of the US Food ..." />
21st-Nov-2020
Pfizer requests emergency authorisation for coronavirus vaccine in US
BBC News :
It will be the job of the US Food and Drug Administration (FDA) to decide if the vaccine is safe to roll out.
It is not clear how long the FDA will take to study the data. However, the US government expects to approve the vaccine in the first half of December.
Data from an advanced trial showed the vaccine protects 94% of adults over 65.
The trial involved 41,000 people worldwide. Half were given the vaccine, and half a placebo.
The UK has pre-ordered 40 million doses and should get 10 million by the end of the year.
If FDA authorisation does come in the first half of next month, Pfizer and BioNTech will "be ready to distribute the vaccine candidate within hours", the two companies said. This would be
remarkably quick for vaccine development - within 10 months of detailing the genetic code. The average wait for approval in the US is nearer eight years.
Pfizer CEO Albert Bourla said on Thursday that the filing for emergency use was a "critical milestone in our journey to deliver a Covid-19 vaccine to the world".
European Commission president Ursula von der Leyen said the EU could move quickly too - by the end of the year.
But there are caveats. Stephen Evans, professor of pharmacoepidemiology at the London School of Hygiene & Tropical Medicine, said both the FDA and the European Medicines Agency (EMA) would "conduct a very careful evaluation".
And BBC health correspondent Naomi Grimley says this vaccine is still a long way off widespread use, not least because it adopts an experimental technology that has never been approved before.
Last week, Pfizer and BioNTech published preliminary data suggesting the vaccine offered 90% protection against Covid-19 and said there were no safety concerns.
Subsequent data released on Wednesday suggested 95% effectiveness.
This effectiveness was also consistent across age groups - essential given the vulnerability of the elderly - as well as ethnicities and gender.
The vaccine also had only mild-to-moderate and short-lived side-effects.
It uses an experimental approach, called mRNA, which involves injecting part of the virus's genetic code into the body to train the immune system.
Antibodies and T-cells are then made by the body to fight the coronavirus.
What other vaccines are being developed?
Data on a vaccine made by US company Moderna also suggests nearly 95% protection. It too uses the mRNA approach.
In terms of development it is believed to be not far behind the Pfizer/BioNTech vaccine.
An Oxford University/AstraZeneca vaccine is still undergoing trials but has shown promising results, with a strong immune response in the elderly. The UK has ordered 100 million doses.
It is made from a weakened version of a common cold virus from chimpanzees, that has been modified to not grow in humans.
There are also similarly promising results from trials of another vaccine developed in Russia, called Sputnik. It works like the Oxford vaccine.
Other vaccines are in late testing stages in China and Russia.


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Select a different port to view its details: Akita, Japan Annular Solar Eclipse Position Aomori, Japan Beppu, Japan Boracay, Philippines Busan, South Korea Da Nang, Vietnam Da Nang/Hue (chan May),vietnam Gamagori, Japan Gunkanjima (hashima Island Scenic Cruising), Japan Hakata, Japan Hakodate, Japan Halong Bay/Hanoi (cai Lan), Vietnam Hibiki, Japan Himeji, Japan Hiroshima, Japan Ho Chi Minh City (phu My), Vietnam Hong Kong Hualien Ishigaki, Japan Ishinomaki, Japan Iwakuni, Japan Jeju (seogwipo), South Korea Kagoshima, Japan Kanazawa, Japan Kanmon Straits, Japan Kaohsiung Kobe, Japan Kochi, Japan Korsakov (yuzhno-sakhalinsk),russia Kota Kinabalu, Malaysia Kumano, Japan Kushiro, Japan Maizuru, Japan Manila, Philippines Matsuyama, Japan Miyako, Japan Miyakojima, Japan Miyazaki (aburatsu), Japan Nagasaki, Japan Nagoya, Japan Nha Trang, Vietnam Niigata, Japan Okinawa, Japan Osaka (for Kyoto), Japan Otaru, Japan Sakaiminato, Japan Sakata, Japan Sasebo, Japan Shanghai Shimizu (for Mt. Fuji), Japan Shiretoko Peninsula (scenic Cruising), Japan Singapore Taipei (keelung) Takamatsu, Japan Toba, Japan Tokushima, Japan Tokyo (yokohama), Japan Toyama, Japan Tsuruga, Japan Vladivostok, Russia Wakayama, Japan Xiamen Yatsushiro, Japan Yeosu, Korea Yokkaichi, Japan
Yokohama and Edo began life as sleepy fishing villages. That changed in the early 17th century after Tokugawa Ieyasu became Shogun. Edo became the center of political power in Japan, a position the city retained even after the restoration of Imperial rule in 1866.
Contemporary Tokyo may be the most astonishing city on earth. It's a paradoxical mix of ancient tradition and postmodern culture. The Ginza - an international shopping mecca - stands near the serene grounds of the Imperial Palace, and the hyper-speed of 21st century consumerism is mysteriously reconciled with the elegance and serenity of traditional culture. Tokyo provides the traveler with a dizzying experience.
With the Meiji Restoration of 1868, Edo was renamed Tokyo, the "Eastern Capital," to distinguish it from the old imperial capital at Kyoto, the "Western Capital."
Imperial Palace Plaza
The residence of Japan's Imperial Family boasts a large park area surrounded by moats and massive stone walls in the center of Tokyo.
Dedicated to the Emperor Meiji, the father of modern Japan, the Meiji Shrine stands in a dense forest glade at the very heart of Tokyo. Its setting symbolizes the separation of the spiritual from the worldly.
Sensoji Temple
Sensoji was built to honor Kannon, the goddess of mercy in the early 7th century. Today, Sensoji Temple is Tokyo's oldest temple.
Tokyo Tower
Taller than the Eiffel Tower by approximately 30 feet, Tokyo Tower is in the record books as Japan's 2nd highest self-supporting iron structure at 1,092 feet.
Great Buddha of Kamakura (Diabutsu)
This monumental outdoor bronze statue of Amida Buddha is located at the Kôtoku-in Temple in Kamakura. According to temple records, it probably dates back to 1252 in the Kamakura period.
Hakone Ropeway-Owakudani-Lake Ashi
Japan's famed Hakone National Park, a ropeway journey that promises such spectacular views as the crystal-clear waters of Lake Ashi and the volcanic fumes of Owakudani.
Mount Fuji is the highest mountain in Japan at 12,389 feet, and one of Japan's "Three Holy Mountains." Its exceptionally symmetrical cone is a well-known symbol of Japan.
Sankeien Gardens
Once the private gardens of a wealthy silk merchant, Sankeien Gardens features sculpted trees, lily ponds, graceful bridges and historic buildings collected from around Japan.


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Police Officer, Who Killed 20-yr-old Lady in Ajegunle, Dismissed from Service
April 19, 2019 emmanuelNewsNo Comment on Police Officer, Who Killed 20-yr-old Lady in Ajegunle, Dismissed from Service
Daniel Ojo, the officer who shot dead one Adaobi Ifeanyi and wounded another Emmanuel Akomafuwa in the Ajegunle area of Lagos state, has been dismissed from service and declared wanted.
This was disclosed Thursday by Zubairu Muazu, Lagos commissioner of police, while addressing journalists at the command headquarters, Ikeja.
Ojo, alongside five other policemen, had on April 13 opened fire on Ifeanyi who died on the spot.
The five policemen were however subjected to orderly room trial while Ojo escaped.
"On April 13, 2019 at about 7:00am, police officers attached to Trinity Police Station who were suspected to be involved in the shooting of Adaobi Ifeanyi and Emmanuel Akomafuwa at Akpiri Street, Olodi Apapa, were arrested and detained," he said.
"Inspector Dania Ojo who escaped immediately after the shooting was declared wanted. The other police officers were subjected to internal disciplinary proceedings at the command headquarters Ikeja.
"Investigation revealed that Inspector Dania Ojo unilaterally carried out the shooting without consideration to laid down procedures on the use of firearm.
"He is therefore, found guilty of abuse of power, unlawful and unnecessary exercise of authority.
"He is thereby dismissed from the Nigeria Police Force and declared wanted. Upon arrest, he will be charged to court for murder."
Ajegunle, Police Officer, Shooting
Onnoghen Rejects CCT Judgment, Heads to Appeal Court
'We Collected N5m Ransom' – Alleged Kidnappers of Lagos Fire Service Chief Confess


Cheese and Rice! I have managed to sad myself right into depression. But, I'm not having it! Nope. Enough.
If I had to analyze myself, I would say my mood of late has been a culmination of several pretty big events.
1) My Nannie, who was a HUGE bright loving light in my childhood, turned 90 on the 23rd. My mom went over to England to surprise her and to celebrate her birthday. I have to face the very real fact that the odds are I will never see my Nannie again.
2) Nic turns 18 next month. I've done post after post on how I feel about that (click on the 'Motherhood' category).
While I am grateful for everything I have, and blessed beyond my wildest dreams when it comes to friends, family and those most important things that cannot be bought, I worry.
I worry that I have no savings, no retirement plan, no health insurance to turn to with my very real health issues. Very easily interpreted by an imaginative mind into: I have no future.
4) I'm beat! Seriously tuckered out. It's been a hell of a few years!
I stopped drinking, asked for a divorce, got the divorce, was almost homeless, was unemployed, moved, got a job, got my smile back and started a blog to share it all. Throughout all of that I've dealt with my heart condition, my lung disease and penny by penny, caught up with past due bills and by the grace of God – I made it!
5) The tooth. This will be the last time I mention it. (Until I get it pulled, then I'm all up in your eyes with a post about that) But being physically knocked off my perch was the final straw for this camels back.
Not once have I wanted to drink through any of this.
I have got to focus on the positive, because God hasn't let me down yet.
So what the heck am I doing not using that smile?
I'm glad I blogged about how I was feeling at the time though. I hope that maybe someone who feels like I felt, but wouldn't say what I said – knows that there is ALWAYS the choice to decide to be happy anyway.
I am grateful. I am loved. I am human. And I'm going to have times when I feel overwhelmed – and those times will teach me how to be stronger, without putting armor on. I have learned to reach out. I have learned I don't have to put on my wonder woman cape. I am enough.
I've done an awesome job of climbing over obstacles, and even though my muscles are a bit sore (I really should stretch before all that climbing), it's so great to get to the other side.
Out of the dark, up and over into the light of my loved ones.
"I have your son in the health office – he says he has a headache and is nauseous".
Nic get's on the phone.
Nic: I don't want to be here – I'm having a really bad day".
Honesty really racks up the points in my book. Honesty will earn you respect, and today earned me using my lunch to leave work, drive to his school and collect him.
I didn't need the details yet, he told the truth and from the tone of his voice I got it.
Sometimes, we just want to go home. We're done. We want comforting and to be surrounded by comfort.
I pulled up to the school and sprung him. I got the scoop about what possibly could have ruined his day in the whole hour and 20 minutes he was there. I won't share the details – that's not fair to him, but suffice it to say – he was in fact having a pretty crappy day.
Yes, he needs to learn to 'decide to be happy' to 'soldier on in the face of adversity' and to 'not take things so personally'. But he's 17. I'm in my 40's and am still honing those skills.
When you're a teenager, sometimes it does feel like your entire world is crumbling down around you, and you just want a time-out.
I am SO very grateful that my son can be honest with me. Oh, I know. I'm not so naive as to believe that he tells me everything, and nor should he. But when it really counts – we're close enough that he trusts he can tell me the truth and not regret doing so.
Our ride from his school to our house was filled with conversation, observations, lessons and advice. Of course I stressed the importance of not missing anymore school – about not letting people ruin his day. That he can't run away from every problem. About resentments – how futile they are. Metaphors flowed. "Nic, resenting them is like taking poison and expecting them to die!" Concerns were soothed, smiles were exchanged and I felt so very blessed.
No. He's not my little boy anymore. No, I can't save him from the world. But today I could give him a chance to regroup. To feel loved. To take a breath and collect his thoughts and I could take a rare opportunity to share some wisdom and experience with him.
When my grandson or granddaughter calls him years from now having a bad day, I hope he picks them up. Figuratively and literally. And I'm pretty sure he will. Because this young man who I am so lucky to call my son – is a kind-hearted, sensitive, funny, bright, loving soul.
6:00 a.m. Alarm goes off.
6:10 a.m. Take breakfast in to my sleeping teen.
6:30 a.m. Teen has eaten and arisen and is checking his Facebook with 10 minutes left to get ready for school.
6:40 a.m. I see my son out the backdoor, give him a quick hug and he says those words to me. "See you when I get back when you get back".
I stand on the back porch and wave. It's dark outside, so I'm mostly waving at my sons shadowy outline – and it waves back. When I can't see him anymore I go into the house to grab another cup of coffee and watch some more news before getting ready.
7:00 a.m. Get ready myself.
I mentioned yesterday to a friend that I feel like I'm stuck in the movie 'Groundhog Day' lately. And I do. But, this morning routine I'll keep.
7:00 a.m. Blessed to have a job to get ready for!
I sat outside while it was gently sprinkling and sipped my coffee and had such a HUGE wave of gratitude wash over me.
I was pondering recent events and appreciating the scenery and for a sudden second, KNEW all of my needs were, and would be met.
I was aware in one moment of time of how beautiful life is, how blessed I am for my friends and family and that everything is going to be alright.
Little God whisper? Maybe. Seems like a great way to start the day to me!


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If you send bulk messages from WhatsApp, the company can sue you
WhatsApp, in its latest bid to prevent frauds, has decided to take some actions. The company has decided that it will take legal action against companies that are found to be sending bulk messages through Whatsapp with the help of third-party clones. At the moment, WhatsApp does not allow sending bulk messages and it also limits message sending up to a certain limit. However, certain mods for WhatsApp such as GBWhatsApp lets you do that.
Company's spokesperson has said that non-personal use of the platform is not what WhatsApp is intended for. Already, we have heard that WhatsApp has served some cease and desist notices to companies who have violated its regulations using clone apps and other services.
In a post written by WhatsApp, the company said that "Beginning on December 7, WhatsApp will take legal action against those we determine are engaged in or assisting others in abuse that violates our Terms of Service, such as automated or bulk messaging, or non-personal use, even if that determination is based on information solely available to us off our platform,"
This information was posted by WhatsApp on its FAQ or frequently-asked-questions page which is titled as Unauthorised usage of WhatsApp. At the moment, WhatsApp has not revealed what type of legal action they would take in such cases but we do know that actions will be taken.
WhatsApp also published a whitepaper back in February to fight bulk messages and automated behaviour. In the White Paper, the company revealed "We have built sophisticated machine learning systems to detect abusive behaviour and ban suspicious accounts at registration, during messaging, and in response to user reports We remove over two million accounts per month for bulk or automated behaviour – over 75 per cent without a recent user report,"
But a new report reveals that firms are using a tool which costs just Rs. 1000 for bypassing WhatsApp's restrictions to send bulk messages.


The Mission of the United Methodist Men is helping men grow in Christ so others can grow in Christ. We believe that our relationship with God determines our relationship with others and the boundaries of our church's property line will not determine the breadth, scope and reach of our ministry.
A significant part of our ministry beyond fellowshipping and encouraging each other is reaching out to others. Major events within the church include an annual Men's Day and an annual men's cookout. This past year, Men's Day was expanded to include two spirit-filled revival nights. The men's outreach of Mt. Zion United Methodist Church includes supporting the Lawnside School by providing a student designated by the school with a computer, school supplies and assisting with renovations when needed. Additionally, the men of Mt. Zion consistently support the church's Thanksgiving and Christmas outreach campaigns among other ministries.


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Frank Maldarelli, M.D., Ph.D.
Building 535, Room 108E
fmalli@mail.nih.gov
HIV Dynamics and Replication Program
Head, Clinical Retrovirology Section
Dr. Maldarelli heads the Clinical Retrovirology Section, which develops and implements clinical protocols to elucidate mechanisms underlying the emergence of HIV drug resistance in vivo, the dynamics of infection under treatment, and the role of resistance mutations in the efficacy and failure of subsequent treatments. Representing the clinical research arm of the HIV Dynamics and Replication Program (HIV DRP), Dr. Maldarelli is an Attending Physician in the NIH NIAID/CCMD HIV Clinic and has established extensive collaborations between the HIV DRP in Frederick and both the NCI HIV and AIDS Malignancy Branch and the NIAID HIV clinical research program in Bethesda.
Cancer and Viruses
HIV/AIDS and Related Malignancies
HIV Drug Resistance
Data Science and Computational Biology
Clinical Studies of HIV Drug Resistance
The Clinical Retrovirology Section develops and implements clinical protocols to elucidate mechanisms underlying the emergence of HIV drug resistance in vivo, the dynamics of infection under treatment, and the role of resistance mutations in the efficacy and failure of subsequent treatments.
In the first of three projects conducted by the Clinical Retrovirology Section, our goal is to determine the dynamics of viral replication in HIV-infected patients on suppressive antiretroviral therapy (ART). These studies are being extended in clinical trials performed at NIH and elsewhere to determine the levels of viremia when treatment regimens are either simplified or intensified. We are also exploring new strategies to decrease reservoirs of HIV-1 in infected individuals.
In a second research project, we are investigating the genetic structure of HIV populations in infected individuals. We are using the single-genome sequencing technology developed by the Translational Research Section to analyze and understand the accumulation of genetic variation in the gag/pol and env genes of HIV-1 in a number of different patient groups, including chronically infected patients, both naive and on therapy, as well as in primary and early HIV-1 infection. We are complementing existing single-genome sequencing and allele-specific PCR assays with next-generation sequencing and new single-cell assays for cell-associated HIV RNA and DNA. We are determining precise estimates of the roles of population size, genetic drift, selection, and recombination in shaping HIV populations. The goal of this study is to understand the nature of the forces (mutation, selection, drift, recombination) that mold the genetic diversity of virus populations before and after ART is introduced.
The third project is focused on elucidating the mechanisms of persistent viremia in vivo. We are conducting clinical trials of targeted interventions to characterize HIV reservoirs in individuals suppressed on ART. We are determining the role of generalized immune activation and gut-associated lymphoid tissue (GALT) on persistence using nonabsorbable antibiotics to specifically reduce gut bacteria, and studying the effects of specific antigenic activation on HIV using immunization and sampling protocols. We are also investigating the role of target cell number on HIV reservoirs by studying the effects of cytotoxic chemotherapeutics on HIV viremia, and we are investigating the role of innate immunity in HIV persistence by studying the effects of the innate immune modulator interferon alpha 2b.
NIH Scientific Focus Areas
Microbiology and Infectious Diseases
Publication Link
View Dr. Maldarelli's PubMed Summary
View Dr. Maldarelli's ORCID Bibliography
Publication File
View Dr. Maldarelli's Complete Bibliography (December 2021)
Selected Key Publications
Dynamic shifts in the HIV proviral landscape during long term combination antiretroviral therapy: Implications for persistence and control of HIV infections
Anderson EM, Simonetti FR, Gorelick RJ, Hill S, Gouzoulis MA, Bell J, Rehm C, Pérez L, Boritz E, Wu X, Wells D, Hughes SH, Rao V, Coffin JM, Kearney MF, Maldarelli F
Viruses. 12: 136, 2020. [ Journal Article ]
Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors
Patro SC, Brandt LD, Bale MJ, Halvas EK, Joseph KW, Shao W, Wu X, Guo S, Murrell B, Wiegand A, Spindler J, Raley C, Hautman C, Sobolewski M, Fennessey CM, Hu WS, Luke B, Hasson JM, Niyongabo A, Capoferri AA, Keele BF, Milush J, Hoh R, Deeks SG, Maldarelli F, Hughes SH, Coffin JM, Rausch JW, Mellors JW, Kearney MF
Proc Natl Acad Sci U S A. 116(51): 25891-99, 2019. [ Journal Article ]
No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication
Bozzi G, Simonetti FR, Watters SA, Anderson EM, Gouzoulis M, Kearney MF, Rote P, Lange C, Shao W, Gorelick R, Fullmer B, Kumar S, Wank S, Hewitt S, Kleiner DE, Hattori J, Bale MJ, Hill S, Bell J, Rehm C, Grossman Z, Yarchoan R, Uldrick T, Maldarelli F
Sci Adv. 5(9): eaav2045, 2019. [ Journal Article ]
Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo
Simonetti FR, Sobolewski MD, Fyne E, Shao W, Spindler J, Hattori J, Anderson EM, Watters SA, Hill S, Wu X, Wells D, Su L, Luke BT, Halvas EK, Besson G, Penrose KJ, Yang Z, Kwan RW, Van Waes C, Uldrick T, Citrin DE, Kovacs J, Polis MA, Rehm CA, Gorelick R, Piatak M, Keele BF, Kearney MF, Coffin JM, Hughes SH, Mellors JW, Maldarelli F
Proc. Natl. Acad. Sci. USA. 113: 1883-8, 2016. [ Journal Article ]
HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
Maldarelli F, Wu X, Su L, Simonetti FR, Shao W, Hill S, Spindler J, Ferris AL, Mellors JW, Kearney MF, Coffin JM, Hughes SH
Science. 345: 179-83, 2014. [ Journal Article ]
Dr. Frank Maldarelli received his Ph.D. from the City University of New York and his M.D. from Mount Sinai School of Medicine. After completing his residency in internal medicine at The Columbia-Presbyterian Hospital, New York, he joined the Laboratory of Molecular Microbiology at the National Institute of Allergy and Infectious Diseases (NIAID) as a Medical Staff Fellow. In 1998, Dr. Maldarelli joined the HIV Drug Resistance Program (HIV DRP, renamed the HIV Dynamics and Replication Program in 2015) in the National Cancer Institute (NCI) as a Staff Clinician and Head of the In Vivo Biology Group, which was later renamed the Clinical Retrovirology Section. In 2012 he was appointed as a Tenure-Track Investigator, and he was promoted to a tenured Senior Investigator position in 2018. Representing the clinical research arm of the HIV DRP, Dr. Maldarelli has established extensive collaborations between the HIV DRP in Frederick and both the NCI HIV and AIDS Malignancy Branch and the NIAID AIDS clinical research program in Bethesda. He is an Attending Physician in the NIAID/CCMD HIV service, the NCI Liaison to the Leidos HIV Molecular Monitoring Core, and a Scientific Committee Member of the International Workshop on HIV Drug Resistance. He served on the NIAID Institutional Review Board (as Chair and Vice-Chair), NIH Infectious Disease Advisory Board, Scientific Advisory Committee of the American Federation for AIDS Research, and Review Panel for the Henry M. Jackson Foundation for the Advancement of Military Medicine. He was a faculty member of the International Society of Infectious Diseases HIV Training Program, NIH Infectious Disease Consult Service, and Center for Bio-Medical Communications Infectious Disease Board Review Course and a lecturer in the Washington D.C. community outreach PACT Program. His awards include the NCI Leading Diversity Award in 2010, NIH Director's Group Award in 2015, Center for Cancer Research (CCR) Group Award in 2016, and multiple Staff Recognition, NIH Bench-to-Bedside, and Intramural AIDS Targeted Antiviral Program (IATAP) awards. Dr. Maldarelli is a member of a number of committees, and he chairs the CCR Non Human Primate Scientific Review Committee, Data Safety Monitoring Board for the GRAVITY Study, and Tenure Track Selection Committee for Critical Care Medicine. He currently serves on the Editorial Board of the Journal of Virology.
There are no open positions at this time. Check back again later, or take a look at CCR's Careers page.
Postbaccalaureate Fellow (CRTA)
Lindsey Adams, B.S.
Special Volunteer
Matthew Adan, B.S.
Advanced Practice Nurse
Jessica Earhart, M.S.N.L.M., B.S.
Scientist (Contr)
Zehava Grossman, Ph.D.
Kristi Huik, Ph.D.
Associate Research Physician
Chuen-Yen Corey Lau, M.D.
Postdoctoral Fellow (Cancer Prevention Fellowship Program)
Erin Madeen, Ph.D.
Ariana Savramis, B.A.
Postdoctoral Fellow (Visiting)
Thuy Nguyen, Ph.D.
James Virga, B.S.
Mary-Elizabeth Zipparo, B.S.
New Investigator Scholarships, Conference on Retroviruses and Opportunistic Infections
Kristi Huik was awarded a New Investigator Scholarship to present her research findings in the 2020 Conference on Retroviruses and Opportunistic Infections (CROI). CROI scholarship awardees in previous years include Elizabeth Anderson and Camille Lange in 2018 and 2017, Sarah Watters in 2015, and Francesco Simonetti in 2014.
2019 Presentation Award in Microbiology, Annual Biomedical Research Conference for Minority Students
Natalie Lindo received a 2019 Presentation Award in Microbiology for presenting her research findings at the Annual Biomedical Research Conference for Minority Students.
Scholarship Award, International Workshop on HIV Drug Resistance and Treatment Strategies
Kristi Huik was awarded a scholarship to attend the 2018 International Workshop on HIV Drug Resistance and Treatment Strategies in Johannesburg, South Africa, to give an oral presentation on the latest findings of her research project ("Mechanism of Emergence of Resistance of T97A during Dolutegravir Therapy").
Young Scientist Sponsorship, 68th Lindau Nobel Laureate Meeting
Kristi Huik was awarded a full sponsorship by the Estonian Academy of Sciences to participate in the 68th Lindau Nobel Laureate Meeting in June 2018. She received this award based on her outstanding research on the role of host genetic factors in HIV acquisition, HIV drug resistance, and molecular epidemiology of other infections while she was a Ph.D. student at the University of Tartu before joining the Maldarelli lab. The annual Lindau Nobel Laureate Meeting is a prestigious gathering of around 30 Nobel Laureates and 500-600 young scientists — including postdoctoral fellows, Ph.D. students, and undergraduates — who convene to communicate leading issues in physiology and medicine in a forum that includes lectures, panel discussions, poster sessions, master classes, Agora talks, and science walks.
Travel Awards, HIV DRP Think Tank Meeting
Elizabeth Anderson received a $1000 travel award from the HIV DRP for one of the two best presentations by NCI fellows at the 2018 HIV DRP Think Tank Meeting. Francesco Simonetti received this Travel Award for his presentation at the 2014 HIV DRP Think Tank Meeting.
Travel Award, Fall HIV/AIDS & Cancer Virology Think Tank Meeting
Paula Rote won a $1000 travel award for her outstanding talk at the 2017 Fall HIV/AIDS & Cancer Virology Think Tank Meeting. This annual Think Tank meeting on the NIH-Bethesda campus provides a venue for students, postdoctoral fellows, and staff scientists to present emerging work and hypotheses in the field of cancer virology. The Think Tank travel awards are provided by the Center of Excellence in HIV/AIDS & Cancer Virology, Center for Cancer Research, NCI.
Diversity Career Development Program, NIH
Camille Lange graduated from the Diversity Career Development Program (DCDP) at NIH in 2016. DCDP graduates were nominated and selected among a group of talented NIH staff for participation in this program.
Scholarship Award, 2016 Towards an HIV Cure Symposium and 21st International AIDS Conference (AIDS 2016)
Elizabeth Anderson was awarded a scholarship to attend the 2016 Towards an HIV Cure Symposium and the 21st International AIDS Conference (AIDS 2016) in Durban, South Africa. She presented the latest findings of her research project ("Intra-patient, full length analysis of HIV gag genetic variation identifies regions of variability") at both meetings.
2015 NCI Director's Award
Members of the NCI HIV Integration Sites Analysis (ISA) team received a group award at the NCI Director's Award ceremony in November 2015 "for discoveries on HIV survival during antiretroviral therapy, revealing the importance of integration site and clonal expansion." The ISA group award recipients included Stephen Hughes, Andrea Ferris, Shawn Hill, Mary Kearney, Frank Maldarelli, Wei Shao, and Jonathan Spindler (HIV DRP); Francesco Simonetti (University of Milan); John Coffin (Tufts University); John Mellors (University of Pittsburgh); and David Wells, Ling Su, and Xiaolin Wu (Leidos Biomedical Research, Inc.).
NIH Postbac Poster Day Award
Tiffany Tanzosh was honored for presenting one of the best posters on NIH Postbac Poster Day in 2012. Established in 2001, NIH Postbac Poster Day added a judging component in 2011 to highlight the contributions of postbaccalaureate fellows to the NIH Intramural Research Program. Awardees are recognized for having authored posters that score in the top 20% of all posters presented.
Shiva Ambardar
Elizabeth Anderson, Ph.D.
Postdoctoral Fellow, Postbaccalaureate Fellow
Himanshu Batra, Ph.D.
Jennifer Bell, R.N., B.S., C.C.R.C,
Protocol Coordinator
Giorgio Bozzi, M.D.
Infectious Disease Fellow
Margaret Caplan, M.D.
Karoll Cortez, M.D.
Staff Clinician
Francesca Cossarini, M.D.
Kristen Danley, M.D.
Summer Student
Sophie Dean
Gabriella Diaz, R.N., B.S.N.
Monica Gouzoulis, B.S.
Postbaccalaureate Fellow
Junko Hattori, Ph.D.
Shawn Hill, M.S., M.B.A.
Research Biologist
Kristen Kent, B.S.
Daniel Kordella, M.S.
Laure Kouyoudjian, P.A.C.
Nicholas Kovacs, Ph.D.
Natalie Lindo, B.S.
Camille Lange, Ph.D.
Charmaine Peters, M.D.
Carrie Poethke, D.O.
Paula Rote, M.D.
M.D. Student
Francesco Simonetti, M.D.
Rhoda Smith, R.N.
Tiffany Tanzosh, B.S.
Sarah Watters, Ph.D.
Predoctoral Fellow
Eleanor Wilson, M.H.S., M.D.


We are very happy to announce that our leadership simulation, Gamechangers™, was awarded gold in the corporate category at the 2015 Serious Games Conference.
The Serious Play Conference is an annual leadership conference for people who work with designing, managing and implementing games in professional organisations.
Gamechangers is a leadership simulation about strategy execution and stakeholder cooperation in large organisations. It focuses on how to engage stakeholders as you carry out an important strategic initiative.
Read more about Gamechangers here.


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https://www.sheltonherald.com/news/community/article/Former-SHS-teacher-charged-with-Disorderly-13952857.php
Former SHS teacher charged with Disorderly Conduct on student
Published 11:04 am EDT, Wednesday, September 9, 2015
On Sept. 8, 57 year old George Perduta of Kensington turned himself into police for an active arrest warrant. Perduta was charged with Disorderly Conduct and released on a $500 bond. Perduta was given a court date of Sept. 22 in Derby Court.
The arrest came from a complaint that was received in April. A 17 year old female student from Shelton High School reported that she went out to dinner with George Perduta. Perduta was a teacher at Shelton High School when this incident occurred.
The victim claims that Perduta asked about their relationship status during dinner which made her uncomfortable. The victim reported that after dinner Perduta went to kiss her on the lips, but she moved her head down and he kissed her on the forehead.


The Blue Jackets Prospects jumped to 2-0 at the Traverse City tournament according to the CBJ and The Dispatch. Oliver Bjorkstrand had a 5 point game with 2 goals and 3 assists to add to his 1 goal and 1 assist in the first game to illustrate the potential of this young prospect.
The good news is that Bjorkstrand is not at all alone on this team, with Sonny Milano, Kerby Rychel there to help him, while TJ Tynan adds the leadership to the group. It is really exciting to see this prospect group performing so well, and they will match up against the Rangers prospects tomorrow.
Because of the depth on the parent club, many of this group will end up playing in Cleveland this year for the Lake Erie Monsters.
This is a great opportunity for this group to form before the season starts, and it is to be hoped that it yields some significant benefits. Needless to say, following this afternoon's football game, there are going to be fans in Cleveland looking for a winning team to follow. This group of players has an excellent opportunity to establish a winning tradition with the Monsters that will aid the parent club for years to come.
These young players are focused on trying to make the NHL squad, but there isn't much room up there, especially for forwards. These things don't play out on paper, they have to play out on the ice, but there is no shame for a prospect being unable to crack this Blue Jackets line up. But for now, this group of young players is looking VERY strong! Which is a great thing for the CBJ down the road. Keep in mind that there are two expansion teams coming into the league over the next couple of years. These players are going to find opportunity soon. They will be best prepared for it with a good year of AHL play under their belt. It's a good time to be a Jackets fan!