text:
Reaction mass of 4-sulfophthalic acid and 3-sulfophthalic acid
combined repeated dose and reproduction / developmental screening
read-across based on grouping of substances (category approach)
REPORTING FORMAT FOR THE CATEGORY APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
The read across follows Scenario 5 - Qualitatively and quantitatively similar effects are caused by a common compound, which is formed from all category members (as described in the 2017 Read-Across Assessment Framework document).
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
TARGET: Reaction Mass of 4-sulphophthalic acid and 3-sulphophthalic acid (ratio 3:1)
SOURCE: Sulfophthalic acid sodium and ammonium salts
3. CATEGORY APPROACH JUSTIFICATION
Sulphophthalic acid sodium and ammonium salts are different organic salts of a common acid, sulphophthalic acid. The salts dissociate rapidly in the medium (water) to the common sulphophthalic acid anion and to their different counter ions. The counter ions ammonium and sodium do not influence the solubility and the toxicity of the category members.
4. DATA MATRIX
See Read Across document attached to CSR
OECD Guideline 422 (Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test)
- Name of test material (as cited in study report): Produkt SPS
- Test-substance No.: 11/0629-1
- Lot/batch No.: 78522224U0
- Purity: Trisodium 4-sulphonophthalate: 25.5 g/100 g; Trisodium 3-sulphonatophthalate: 7.6 g/100 g; Disodium phthalate: 1 g/100 g; Sulphate: 60.6 g/100 g; Water: 4.8 g/100 g; Sum: 99.5 g/100 g; Determined by 1H-NMR-analysis
- Homogeneity: The test substance was homogeneous by visual inspection
- Storage stability: The stability of the test item under storage conditions over the study period was guaranteed by the sponsor, and the sponsor holds this responsibility
- Storage conditions: Room temperature
- Physical state/ colour: Solid/ white
- Expiry date: December 10, 2012
Wistar
- Source: Harlan Laboratories, B.V.
- Age at study initiation: 12 weeks
- Weight at study initiation: Males: 287 to 348 g; Females: 188 to 222 g
- Housing: individually
- Diet: ad libitum
- Water: ad libitum
- Acclimation period: Eight days under test conditions after health examination. Only animals without any visible signs of illness were used for the study.
- Temperature (°C): 22 ± 3 °C
- Humidity (%): 30 - 70%
- Air changes (per hr): 10 - 15 air changes per hour
- Photoperiod (hrs dark / hrs light): 12/12
oral: gavage
PREPARATION OF DOSING SOLUTIONS:
The dose formulations were prepared daily using the test item as supplied by the Sponsor.
Produkt SPS was weighed into a glass beaker on a tared precision balance and approximately 80% of the vehicle was added (w/v). Using an appropriate homogenizer, a homogeneous suspension was prepared. Having obtained a homogeneous mixture, the remaining vehicle was added. Separate formulations were prepared for each concentration.
Homogeneity of the test item in the vehicle was maintained during the daily administration period using a magnetic stirrer.
- Justification for use and choice of vehicle (if other than water): the test substance was soluble in the vehicle
On the first treatment day samples from the control group (middle only) as well as three samples (top, middle and bottom) of about 0.5 g of each concentration were taken prior to dosing for analysis of concentration and homogeneity. Samples of about 0.5 g of each concentration were
taken from the middle to confirm the stability (8 days at room temperature (20 ± 5 °C)). On 24- Aug-2012, samples were taken from the middle to confirm the concentration. The aliquots for analysis of dose formulations were frozen (-20 ± 5 °C) and delivered on dry ice to Dr. B. Ludwig
(Harlan Laboratories Ltd., Zelgliweg 1, 4452 Itingen / Switzerland) and stored there at -20 ± 5 °C until analysis.
The samples were analyzed by HPLC coupled to an UV detector following an analytical procedure provided by the Sponsor and adapted at Harlan Laboratories. The test item was used as the analytical standard. Analyzed samples were discarded after approval of the data by the
Duplicates were taken of all samples and were stored at Harlan Laboratories Ltd., Füllinsdorf / Switzerland. The samples were discarded after approval of the data.
Males: Minimum 4 weeks
Females: Approximately 6 weeks
Doses / concentrationsopen allclose all
Doses / concentrations 1
1 000 mg/kg bw/day (actual dose received)
yes, concurrent vehicle
- Dose selection rationale: based on 14-day range finder.
- Rationale for animal assignment (if not random): Performed on the fifth day of acclimatization using a computer-generated random algorithm. Body
weights (recorded on the day of allocation) were taken into consideration in order to ensure similar mean body weights in all groups.
Positive control:
CAGE SIDE OBSERVATIONS / DETAILED CLINICAL OBSERVATIONS: Yes
- Time schedule: Twice daily for mortality, Daily cage-side clinical observations (once daily, during acclimatization and up to day of necropsy).
Additionally females were observed for signs of difficult or prolonged parturition, and behavioral abnormalities in nesting and nursing.
Detailed clinical observations:
Once prior to the first administration of the test item (day 6 of acclimatization) and weekly thereafter (in the gestation period on day 0, 6, 13 and 20 post coitum), detailed clinical observations were performed outside the home cage in a standard arena. Animals were observed
for the following: changes in skin, fur, eyes, mucous membranes, occurrence of secretions and excretions, and autonomic activity (e.g. lacrimation, piloerection, pupil size, unusual respiratory pattern). Changes in gait, posture and response to handling as well as the presence of clonic or
tonic movements, stereotypies or bizarre behavior were also reported.
- Time schedule for examinations: Recorded daily from treatment start to day of necropsy.
FOOD CONSUMPTION:
Males: Pre-pairing period days 1 - 4, 4 - 8, 8 - 11 and 11 - 14 and weekly after pairing period.
Females: Pre-pairing period days 1 - 4, 4 - 8, 8 - 11 and 11 - 14; gestation days 0 – 7, 7 - 14 and 14 – 21 and days 1 - 4 of the lactation.
No food consumption was recorded during the pairing period.
CLINCICAL LABORATORY INVESTIGATIONS:
Blood samples were obtained on the day of the scheduled necropsy from 5 males randomly selected from each group. Blood samples from 5 lactating females from each group were obtained on day 5 post partum. Blood samples were drawn sublingually from all animals under light isoflurane anesthesia. The animals were fasted for approximately 18 hours before blood sampling but allowed access to water ad libitum. The samples were collected early in the working day to reduce biological variation caused by circadian rhythms.
Furthermore, an additional blood sample (0.5 mL) was collected into serum tubes for possible future measurement of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). Serum samples were stored at ≤-75 °C. Any samples remaining at finalization of the study report, are
discarded. The assay was performed under the responsibility of R. Draheim at Harlan Laboratories Ltd. (Füllinsdorf) under internal laboratory quality control conditions to ensure reliable test results.
The following hematology parameters were determined:
Complete Blood Cell Count:
Erythrocyte count, Hemoglobin, Hematocrit, Mean corpuscular volume, Red cell volume distribution width, Mean corpuscular hemoglobin, Mean corpuscular hemoglobin concentration, Hemoglobin concentration distribution width, Leukocyte count (total) ,Differential leukocyte count: Platelet count, Reticulocytes
Coagulation:
Prothrombin time (= Thromboplastin time) and Activated partial Thromboplastin time
CLINICAL CHEMISTRY: Yes
The following clinical biochemistry parameters were determined:
Glucose, Urea, Creatinine, Bilirubin (total),Cholesterol (total), Triglycerides, Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Gamma-glutamyl-transferase, Bile acids, Sodium, Potassium, Chloride, Calcium, Phosphorus, Protein (total), Albumin, Globulin, Albumin/Globulin ratio
NEUROBEHAVIOURAL EXAMINATION: Yes
At one time during the study (males shortly before the scheduled sacrifice and females on day 3 post partum) relevant parameters were performed with five P generation males and five P generation females randomly selected from each group. This FOB assessment was conducted
following the daily dose administration. Animals were observed for the following:
• Cage-side observations: faeces-balls, urine and posture as well as resistance to removal.
• Hand-held observations: muscle tone, constitution, skin, pupil size, palpebral closure, lacrimation, salivation, reaction to handling and general abnormalities.
• Open field observations: level of ambulatory activity including rearing (one minute evaluation), unusual body movements (e.g. spasms, convulsions), gait evaluation, behavior, hair coat, respiration, quantity of faeces-balls and urine.
• Reflexes: blinking, palpebral closure, pinna reflex, extensor thrust response, paw pinch, responsiveness to sharp noise, righting reflex and hearing ability (Preyer's reflex).
• Measurements / Counts: hind limb / fore limb grip strength, rectal temperature.
Any abnormal findings were recorded and, where appropriate, graded in severity.
Additionally, locomotor activity was measured quantitatively for the same animals. Activity was measured with an Activity Monitor AMS-0151 (FMI, Germany). Activity of the animals (based on beam count) was recorded for 6-minute intervals over a period of 30 minutes. These data and
the total activity over 30 minutes were reported.
All animals sacrificed were subjected to a detailed macroscopic examination to establish, if possible, the cause of death. Specimens of abnormal tissue were fixed in neutral phosphate buffered 4% formaldehyde solution.
At the scheduled sacrifice, all animals were weighed and sacrificed by an injection of sodium pentobarbital. All P generation animals were exsanguinated.
Dead pups, except those excessively cannibalized, were examined macroscopically.
All parent animals and pups were examined macroscopically for any structural changes, either at the scheduled necropsy or during the study if death occurred.
For the parent animals, special attention was directed at the organs of the reproductive system.
The number of implantation sites and corpora lutea was recorded for all dams with litters. The uteri of apparently non-pregnant females were placed in a solution of ammonium sulfide to visualize possible hemorrhagic areas of implantation sites.
TISSUE PRESERVATION:
The following tissues from all parental males were preserved in neutral phosphate buffered 4% formaldehyde solution:
Prostate, Seminal vesicles with coagulating gland, Testes (in Bouin's fixative), Epididymides (in Bouin's fixative)
The following tissues from all parental females were preserved in neutral phosphate buffered 4% formaldehyde solution:
Ovaries (with oviduct), Uterus (with vagina)
In addition, from all males and females the following tissues were preserved in neutral phosphate buffered 4% formaldehyde solution:
Gross lesions, Brain, Spinal chord (cervical, thoracic, lumbar), Small and large intestines[2] (incl. Peyer's patches), Stomach (forestomach and glandular stomach), Liver, Kidneys, Adrenals, Lymph nodes (axillary and mesenteric), Urinary bladder, Aorta[1], Heart, Thymus, Thyroids and parathyroids, Trachea and lungs (preserved by inflation with fixative and then immersion), Pituitary gland[1], Spleen, Peripheral nerve (sciatic), Bone marrow (femur), Femur with knee joint[1], Mammary gland (male and female)[1], Pancreas[1], Eyes with optic nerve and harderian gland[1], Lacrimal gland[1], Larynx[1], Nasal cavity[1], Esophagus[1], Salivary glands – mandibular, sublingual[1], Skeletal muscle[1], Sternum with bone marrow[1], Pharynx[1]
[1] only examined by histopathology in case of macroscopic findings indicative of potential toxicity
[2] duodenum, jejunum, ileum, colon, caecum, rectum
All organ and tissue samples to be examined by the study pathologist were processed, embedded and cut at an approximate thickness of 2 - 4 micrometers and stained with hematoxylin and eosin. Additionally, the testis was stained by PAS-hematoxylin. Special stains were used at the discretion of the study pathologist.
Testes, epididymides, prostate, seminal vesicles, ovaries, oviduct, vagina and uterus from all animals of the control and high-dose group were examined. The same applied to all occurring gross lesions. The remaining organs/tissues of 5 randomly selected males and females of the control and high-dose group, respectively, were examined histopathologically. Special emphasis was made on the stages of spermatogenesis and histopathology of interstitial cell structure. Histological examination of ovaries was carried out on the females that did not give birth.
Other examinations:
Organ Weights:
At the scheduled sacrifice, the testes and epididymides of all parental males were weighed separately.
In addition, from 5 males and 5 females killed at the end of the study which were selected for hematology and clinical chemistry examination from each group, the following organs were trimmed from any adherent tissue, as appropriate, and their wet weight taken.
Adrenal glands (weighed as pairs), Brain, Heart, Kidneys (weighed as pairs), Uterus (including cervix), Prostate, Liver, Thymus, Spleen, Thyroid (after fixation), Ovaries (weighed as pairs), Seminal vesicles (inclusive coagulating gland)
The following statistical methods were used to analyze food consumption, body and organ weights, clinical laboratory and reproduction data and macroscopical findings:
• Means and standard deviations of various data were calculated.
• The Dunnett-test (many to one t-test) based on a pooled variance estimate was applied if the variables could be assumed to follow a normal distribution for the comparison of the treated groups and the control groups for each sex.
• The Steel-test (many-one rank test) was applied instead of the Dunnett-test when the data could not be assumed to follow a normal distribution.
• Fisher's exact-test was applied if the variables could be dichotomized without loss of information.
Results of examinations
There were no test item-related deaths. All animals survived until scheduled necropsy. No clinical signs were noted in males and females at any dose level. No findings at detailed weekly clinical observation were noted in males and females at any dose level.
CLINICAL SIGNS AND MORTALITY
BODY WEIGHT AND WEIGHT GAIN
MALES:
Pre-pairing and Pairing Periods
There were no effects on mean body weight gain and mean body weights at any dose level and in any study phase.
The overall differences in mean body weight gain at the dose levels of 0, 100, 300 and 1000 mg/kg bw/day were: +15%, +14%, +13% and +14% during the pre-pairing period and +5%, +5%, +5% and +6% during the pairing period (percentages refer to the body weight gain within the period).
FEMALES:
Pre-pairing, Pairing, Gestation and Lactation Periods
No test item-related effects on mean body weight and mean body weight gain were noted. At a dose level of 1000 mg/kg bw/day, statistically significantly higher mean body weights were noted (+6% compared to the control group) at the end of the study. Higher (but not statistically significantly different) mean body weight gain was already noted during the pre-pairing period. This increase was accompanied by higher mean food consumption during the gestation and lactation period. However, in the absence of any other compound-related effect, this minor difference is considered to be rather fortuitous than compound-related.
The overall differences in mean body weight gain at the dose levels of 0, 100, 300 and 1000 mg/kg bw/day were: +8%, +8%, +7% and +9% during the pre-pairing period, +55%, +49%, +54% and +58% during the gestation period and +7%, +6%, +9% and +5% during the lactation period (percentages refer to the body weight gain within the period).
Pre-Pairing Period
There were no effects on mean food consumption at any dose level and in any study phase.
Pre-pairing, Gestation and Lactation Periods
There were no effects on mean food consumption at any dose level and in any study phase. At 1000 mg/kg bw /day, during the gestation and lactation period, mean food consumption was slightly higher (+10% and +15%, respectively) compared to the control group. Also in the pre-pairing
period a trend was observed. Differences in mean food consumption were not statistically significant.
The assessment of the hematology data did not reveal any test item-related effects in males and females at any dose level.
Higher reticulocyte counts were observed in females at 300 mg/kg bw/day, and a lower number of large unstained cells occurred at 100 mg/kg bw/day. In the absence of dose-dependency a compound-related effect can be excluded.
The assessment of the clinical biochemistry data did not reveal any test item-related effects in males and females at any dose level.
Slightly higher urea levels at 300 and 1000 mg/kg bw/day, as well as slightly higher potassium levels at a dose level of 1000 mg/kg bw/day in females were in the range of the historical control data.
NEUROBEHAVIOUR
No findings were noted during the functional observational battery in males or females at any dose level.
Mean body temperatures of males at 1000 mg/kg bw/day were slightly statistically significantly higher than in the control rats. Since the value of 38°C was in the range of the historical control data (37.5-38.6°C) this finding was considered to be incidental.
Locomotor activity was assessed quantitatively in terms of low beam counts in activity monitor. Locomotor activity was not affected by the treatment with the test item in males or females at any dose level.
In males and females no test item-related effects on organ weights were noted.
Absolute testis weights in males at 1000 mg/kg bw/day were statistically significantly higher, confirmed by the values relative to body weight. At this dose level, the testes weight of one male (no. 41) was abnormally high and microscopically a minimal sperm arrest (isolated finding) was observed for this male. Also at 300 mg/kg bw/day, higher absolute (not statistically significant) and relative to body weight (statistically significant) testes weights were noted. All values were in the range of the historical control data however controls at the lower limit and animals treated at 300 and 1000 mg/kg bw/day at the upperer limit. In general, no microscopical correlation to the higher testes weights was noted. Due to these facts, the higher testes weights were considered to be a result of biological variability and not a test item-related effect.
There were no test item-related findings noted at necropsy in males and females.
All gross lesions recorded were considered to be within the range of normal background alterations and showed no dose dependency.
Under the conditions of this experiment, the test item "Produkt SPS" did not induce any test item-related findings in reproductive organs or other organs examined.
The qualitative sperm staging did not reveal any relevant differences in stages of spermatogenesis between control males and males at 1000 mg/kg bw/day. All the findings in reproductive organs were considered to be within the range of normal background lesions which may be recorded in animals of this strain and age.
systemic and local
> 1 000 mg/kg bw/day (actual dose received)
food consumption and compound intake
.No test item-related toxicity findings were noted during 28-days of exposure to male rats . Based on these results, the NOAEL (No Observed Adverse Effect Level) for general toxicity was considered to be >1000 mg/kg body weight/day
There are no oral repeated dose studies on the reaction mass of 4-sulphophthalic acid and 3-sulphophthalic acid (read across target substance). However, an oral repeated dose study is available for the reaction mass of trisodium 4-sulphonophthalate, trisodium 3-sulphonatophthalate, disodium phthalate, and sulphate (read across source substance) and it was used for read-across purposes
The purpose of this study was to generate preliminary information on the possible health hazardslikely to arise from repeated exposure over a relatively limited period of time.The sulphophthalic acid sodium salt reaction mass (read across source substance)was administered to male rats for at least 28 days and to female rats for 14 days.The following dose levels were applied:0(control group), 100, 300, and 1000mg/kg body weight/day. A standard dose volume of 10 mL/kg body weight with a daily adjustment to the actual bodyweight was used. Control animals were dosed with the vehicle alone (water).The following results were obtained:1)all animals survived until scheduled necropsy, 2) No clinical signs were noted in males and females at any dose level, 3) No adverse effects on mean food consumption and mean body weights of males and femaleswere observed at any dose level.No test item-related findings were noted during the clinical laboratory investigations. Based on these results, the NOAEL (No Observed Adverse Effect Level) for general toxicity was considered to be >1000 mg/kg body weight/day.


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Hunter Mahan Calls In From The Deutsche Bank Championship
Filed Under:Deutsche Bank Championship, FedEx Cup Playoffs, Hardy, Hunter Mahan, TPC Boston, Trenni Kusnierek
(Photo courtesy of Steve Saleeba/Elevate Comm.)
BOSTON (CBS) – The world's best golfers have descended upon Norton this week for the annual Deutsche Bank Championship at TPC Boston, which has become a Labor Day Weekend tradition here in New England.
Defending champion Henrik Stenson looks to defend his crown against the best DBC field we've seen in some time, including Hunter Mahan, who spoke with Hardy and Trenni Kusnierek on 98.5 The Sports Hub's Gresh & Zolak program Thursday afternoon.
SEE ALSO: Join The Sports Hub At The DBC!
Mahan is dialed in right now. Or as Hardy puts it, "Out of his mind hitting fairways and greens." His recent hot streak even got him a win at The Barclays last week in what was the first of four events of the FedEx Cup Playoffs.
Mahan can't really explain why he's playing so well, he's just focused right now on hitting his best shot every shot and staying in the moment. Mahan is currently atop the FedEx Cup leaderboard with 3,276 points to his name and three tournaments still to play: the Deutsche Bank, the BMW Championship in Denver and the TOUR Championship in Atlanta.
Once the FedExCup Champion is crowned, the best Americans and Europeans will square off in the Ryder Cup. Mahan hopes his name is called to play for the US.
"It would mean a lot. That's the goal of every European and every American player. Going back to Scotland to play for captain Tom Watson would be a tremendous honor. With the PGA and the win last week I think that puts me in good standing with him. Hopefully this week I can seal the deal."
Sports Hub Events: AT&T Fan Zone At The Deutsche Bank
Mahan, 32, is still chasing that elusive major championship.
He's finished in the top 10 a total of seven times, and he's hoping he can break through next April at The Masters.
Hardy knows just how to help.
"My other broadcasting partner and I have a streak going right now at the Deutsche Bank Championship. If you sit down and talk with us you win a major the next year. If you don't believe me, ask Bubba Watson and Jason Dufner," joked Hardy. "It's happened a couple of times is my point! If, over the course of the weekend, you have the opportunity to sit down with us, I can all but guarantee a major championship next year."
Listen below for Mahan's response, and which major would mean the most to him:
Hunter Mahan Interview
MORE SPORTS FROM CBS BOSTON
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redpajama_set_name: RedPajamaCommonCrawl


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Where is Prichard Colon in 2022? Will the former boxer recover?
Martin Cooper January 6, 2022
Photo by Phelan M. Ebenhack/For The Washington Post via Getty Images
Where is Prichard Colon in 2022? The promising boxer was left in a vegetative state after a 2015 bout with Terrel Williams and underwent an operation last year, prompting interest in his condition.
Who is Prichard Colon?
Prichard Colon Melendez is an American former professional boxer and gold medal winner at the 2010 Panamerican Youth Championship. He was seen as a promising prospect in the sport.
The 28-year-old was born in Maitland, Florida. His parents are Nieves and Richard Colon, a retired serviceman. At the age of ten, his family moved to Puerto Rico so Prichard could represent the island in boxing competitions.
EXPLAINED: What is 'accidental Partridge'?
LIKE & RT to wish Prichard Colon a Happy Birthday! #PBCBirthdays #TeamColon 🇵🇷 pic.twitter.com/K6vvwcORGB
— Premier Boxing Champions (@premierboxing) September 20, 2019
After graduating from high school, Colon started studying business administration at the Universidad del Sagrado Corazon in San Juan, Puerto Rico.
Soon after winning gold at the 2010 Panamerican Youth Championship in the 64kg category, he turned pro with an amateur record of 170–15.
The injury that changed Prichard Colon's life
Three years after turning pro in 2012, Prichard came up against American boxer Terrel Williams at EagleBank Arena in Fairfax, Virginia.
Williams beat Colon, then still a rising prospect, on a ninth round disqualification after Williams knocked Colon down twice and Colon's corner removed his gloves, mistakenly thinking it was the tenth and final round.
"It was a nasty, ugly fight on both sides," wrote Ring TV. The Puerto Rican fighter was docked two points for a low blow by referee Joseph Cooper. Williams had a point removed for rabbit punching.
EXPLORED: Did Jenna Marbles work at Barstool Sports?
Praying for Prichard Colon everyday 🙏🏽🙏🏽🙏🏽 pic.twitter.com/BbDz3bO0eF
— Eddie Chambers (@champfasteddie) October 21, 2015
After the fight, Colon slipped into a coma for 221 days. He was in a persistent vegetative state, confined to a bed and required a wheelchair to move. He suffered a brain bleed from an injury sustained during the bout.
He left the ring under his own power but became dizzy and nauseous in his dressing room, the Guardian reported.
Colon underwent surgery to relieve pressure on his brain after the fight on 17 October 2015.
How is he doing in 2022? Will he ever recover?
A TikTok video resurrected interest in the former boxer. Now, people want to know about Prichard's condition and whether he will ever recover.
The TikTok clip, posted by a user called N1kemo123, was shared in June 2021 and at the time had more than 800,000 likes. "Hope you get well one day Prichard," the user wrote alongside before-and-after clips of the boxer's condition.
So, how is his condition now? Will Prichard Colon ever fully recover? The 28-year-old continues to receive occupational therapy at Brooks Rehabilitation in Orange Park, Florida.
The swelling around his brain required a left hemisphere craniotomy, a removal of part of his skull, to allow the brain to expand and heal.
His mother, Nieves, is now his full-time caregiver. After a visit with a neurologist in September 2017, she was told she should not expect her son to improve beyond an unresponsive wakefulness state (UWS) – previously called the vegetative state.
PROFILED: Who is Ed Litton's wife, Kathy?
Our thoughts and prayers are with Prichard Colon & his family #Pray4Prichard #PrayForPrichard #DiggetTime pic.twitter.com/lbApiR3Ctp
— Golden Boy (@GoldenBoyBoxing) October 20, 2015
People in UWS have a sleep/wake cycle but don't otherwise interact in a meaningful way. However, in March 2018, when at Brooks, it was determined Prichard could communicate with his eyes.
His eyes were calibrated to an augmentative and alternative communication (AAC) device and Prichard was able to answer yes/no questions in English and Spanish at 80 per cent accuracy by looking at his answer choices on the screen, as reported by Brooks.
In June 2018, he began physical occupational therapy. By the beginning of 2019, he could manage some shoulder work, grasp and release pegs, and follow commands. His hands improved and he was able to stand with assistance within one month.
Prichard has since walked about the length of a football field with the help of therapists and some assistive devices. He can also maintain his balance while sitting unsupported for more than five minutes.
Successful surgery
In July 2021, the World Boxing Council (WBC) announced Prichard Colon had undergone more surgery, which had been a success.
"Prichard ended up with serious health consequences after a fight in 2015," the WBC told Boxing Insider.
"In recent weeks it was found a collapse of his skull was pressing on the brain, for which a fragment had to be removed to be replaced by a plate."
Fortunately, the operation went well.
Nieves told the same publication: "The doctor has already come to give the results of my son's surgery, the champion Prichard Colón Meléndez.
"Everything went well. Thank you all for keeping my son in prayers for the huge messages and calls inquiring about us."
We wish Prichard best wishes for his continued recovery.
Martin Cooper
Martin Cooper is a senior editor and writer at The Focus. The man behind the style guide comes from a newspaper and magazine background and has worked in the sports, aeronautical and hospitality industries. While head of production at The Argus he appeared on the Jeremy Vine radio show and worked as a freelancer on the sports desk at The Sunday Times. Martin is also an FA Level 1-qualified coach and took his youth team from division five to division one in two seasons before going out at the top.
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Feb. 13, 2020 / 8:38 AM
British finance minister Sajid Javid quits in Cabinet reshuffle
Don Jacobson
Javid unexpectedly resigned Thursday amid a reshuffling of Prime Minister Boris Johnson's Cabinet. Photo by Will Oliver/EPA-EFE
Feb. 13 (UPI) -- A Cabinet reshuffle by British Prime Minister Boris Johnson Thursday resulted in the unexpected resignation of finance minister Sajid Javid.
Javid resigned from his key government post as chancellor of the exchequer after rejecting an order from Johnson to fire all of his aides. He had previously been expected to keep his job during the Cabinet realignment despite ongoing clashes with Dominic Cummings, Johnson's chief political strategist.
Javid, who has served as chancellor since July when Johnson was first appointed prime minister, was set to deliver the government's first budget within the month. With his resignation he became the shortest-serving British finance chief since 1970.
He was replaced as chancellor by Chief Secretary to the Treasury Rishi Sunak, the government said.
Sunak's appointment is said to be part of an effort to align the treasury more closely with the prime minister's office.
Other key ministers held onto their jobs, including Foreign Secretary Dominic Raab, Cabinet Minister Michael Gove and Home Secretary Priti Patel.
Also sacked Thursday were Business Secretary Andrea Leadsom, Environment Secretary Theresa Villiers and and Housing Minister Esther McVey.
Besides Javid's exit, perhaps the greatest surprise in the Cabinet reshuffle is the firing of Northern Ireland Secretary Julian Smith, who had success securing a deal to end a three-year suspension of the local government.
Britain posts no growth in Q4 amid Brexit issues, election British PM Boris Johnson signs Brexit agreement British chancellor proposes hiking living wage to £10.50, or $13, per hour


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Genesee County ADR Office
900 S. Saginaw Street, 2nd floor
Email: adrclerk@7thcircuitcourt.com
Monday – Friday*
8:00 a.m.- 5:00 p.m.
*Except court closed days.
The Alternative Dispute Resolution office oversees and supports two component programs: case evaluation and mediation. These programs are governed by Michigan Court Rules (MCR) 2,403, 2.404, 2.410, 2.411 and 3.216.
Applications to serve as a case evaluator, a civil mediator or a domestic relations mediator are required. Prior to serving, applicants must be approved by a committee that includes the Presiding Judge of the Civil Division, appointed members of the Genesee County Bar Association and the ADR Clerk.
Presently this office is governed by the court rule requirements of MCR 2.403 and MCR 2.404. Cases that seek money damages are ordered to case evaluation. The ADR Clerk assigns panels, schedules cases and processes the fees and briefs submitted by parties.
The case evaluation panel is comprised of 3 attorneys who review written briefs and hear parties or attorneys orally present their case. The panel members confer, assess the cases and issue a recommended resolution.
The ADR clerk collects case evaluation fess and adjournment fees. Case evaluation fees are $25.00 per attorney evaluator. Checks should be made payable to the attorney evaluators. Fees should be submitted to the ADR Clerk 14 days after receiving notice of the hearing date.
Case evaluation briefs are due 14 days before a scheduled heating. Parties are assessed a late filing fee in the amount of $150.00 if briefs are not filed timely. The $150.00 penalty also applies to cases that are settled or dismissed 14 days prior to case evaluation where summaries were not submitted.
All late fee checks should be made payable to the Genesee County Treasurer and delivered to the ADR Clerk. Late briefs should be delivered directly to the evaluators.
Orders for Adjournments
All orders requesting an adjournment of a case evaluation hearing must address adjournment costs. If costs are assessed or waived by the judge, it must be stated in the order. The ADR clerk must know the amount and the parties responsible for payment. The parties should submit their check(s) to the ADR office. The ADR Clerk will let the judicial staff know that payment has been made.
Approved Case Evaluators
Mediation is a process in which the parties work with a trained neutral to reach an acceptable resolution to the issues involved. Unlike a judicially imposed resolution, the parties seek to find common ground and forge a voluntary settlement. The job of the mediator is help the parties communicate with each other and find mutually beneficial solutions. MCR 2.410, 2.411 and 3.216, governs mediation.
Generally, cases are ordered into mediation during the pre-trial phase. Parties are given 14 days to select a mutually agreeable mediator and notify the ADR Clerk in writing. If the parties cannot agree, the court appoints a mediator from its roster of approved civil mediators.
Mediation must be completed by the discovery deadline noted in the order for mediation. All mediators are required to contact the parties, schedule a mutually agreeable time to conduct mediation and notify the court of the date. Upon completion of mediation, a Mediation Status Report form must be filed with the ADR Clerk. Cases that are not resolved in mediation proceed to case evaluation.
In conjunction with the local Community Resolution Center (CRC), a motion day domestic relations pilot program has been ongoing in the courtroom of Judge David Newblatt. The purpose of this program is to educate judges, lawyers and the public about the benefits of domestic relations mediation.
Approved list of Domestic Relations Mediators


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Who Are the Q?
25.3.2013 by Greg Foster
Concurrent with the controversy of Geert Wilders' tour of Australia, the organisers and sponsors of this event have become objects of media attention, which has led many to ask the question, who are the Q?
They are the Q Society of Australia, a conservative, non-profit association, known (more widely now) for its criticism of Islam and the negative impact of Islamic immigration on Australia.
In their criticisms, they have focused on what they have seen as the inability of Muslims to integrate into Western society. Their campaigns have focused patricularly on what they have seen as the construction of an excessive number of mosques in Australia and the imposition of Halal food onto non-Muslims.
Although the Q Society espouses views and rhetoric on Islam that are characteristically far right, the society holds moderate views on many issues, including but not limited to: friendly relations with Israel, respect for Australian indigenous culture, being open to multiculturalism and even an acceptance amongst its members for gay marriage.
They have sought to position themselves as defenders of Australian values, highlighting their belief in the equality of men and women, a fair go for everyone and the belief that Australian society should remain firmly based on the principles of Western democracy.
In trying to defend these values, they have acted under the pretence of being open to all people, including Muslims but with the firm belief that radical Islam should be no more tolerated in a freedom-loving country than Communism or Fascism.
Though small at present and currently staffed by only volunteers, the Q Society seeks to establish a firm foothold in every state and territory in Australia, with the mission of educating Australians about the dangers of the potential threat of radical Islam in Australia and the impact that it will have on our way of life.


36″ x 48″- 91 x 122 cm, oil paint on linen.It is never to late to find your destination and go after it.
I started my life in a small village in the South of the Netherlands surrounded by water. Sailing was what alleviated the difficulties of hay fever. While moving ever further on to the sea, I became excited about the feeling of limitlessness I saw, being on a vast body of water. The sense of freedom appealed to me and made me happy. I hoped to make a living at sea but as a woman with poor eyesight, the odds were against me.
I decided to try and earn a living as graphic designer and then buy a boat. Working at big companies as an art director was not as satisfying as I thought it would be. The weekends were spent racing across the English channel as crew on various sailboats. Sometimes I went further away and one day in 1985 I saw the most beautiful boat I had ever seen. A sophisticated, elegant, beautiful vessel called Velsheda was participating in a race off the coast of St Malo. My dream was to sail a boat like that but it seemed impossible. This was only for very rich people.
I promised myself to work harder, to make a career and hopefully to get lucky one day, but the dream vanished behind the desk of the office where I had buried myself in work, not realizing I was bored to tears, in the "exciting" world of advertising. When the opportunity came to sail on a windjammer from London to Amsterdam in the Tall ships race, I boarded the Belem. This event provoked in me a deep desire for freedom and adventure. I quit my job and moved to the Caribbean. I couldn't imagine spending my days in the grayness of an unsatisfactory life. It became a long journey into the unknown.
To survive in a strange environment I started decorative painting for people and from there I was asked to paint murals. This led to painting canvasses. I don't think I ever called myself an artist, nor was there a conscious decision to do so. After some painful events in my life, I used the reflection of the images I painted as a way of healing myself and thus the world. It was cathartic and good.
One day, after I painted a large abstract painting inspired by a white Bird of Paradise, I saw the image of the Velsheda again, that day in St Malo. A voice asked me, "What do you really want to paint?" I knew the answer; sailing boats, and especially the J-class. By now the dream of ever being part of sailing the so-called "Greyhounds of the Sea" seemed beyond reach. Painting however was part of my daily life and it allowed me to draw the sailing world into mine. The imagination is a powerful tool. It lifted me up from an undesirable reality to a new world of limitless possibilities. I painted my dream.
I knew I had created the world I live in today and I am taking full responsibility for it. By doing that, I know that I am in control of the rest of my life and I can create anything I want, just like I do as an artist. I can bring every image alive on the canvas, in my imagination and thus in my reality. The picture here shows a person at the helm of a beautiful boat, fully in control of his destiny. The fact that the sun is setting at the end of a long day does not bother him. It is the powerful feeling of moving toward the ever-expanding horizon. It is a happy feeling of moving towards infinite possibilities.
Why is he such an inspiring figure to me? We have nothing in common but our name. My name is Jacobina Trump. This never was a problem in the past, but lately as you can imagine, the reactions of people to my last name have changed. Ten years ago, when I was still married, I used to answer the question "Any kin?" with, "Oh no, I married the right one." Alas, those days are gone. I thought about changing my name, but my original family name has a difficult pronunciation in America and I had already established a website for my art.
My last name is powerful. Not too long ago when the access to a private island was temporary closed due to construction, the guard said to me, "If your name was Trump I would let you through." I laughed and said, "Let me show you my driver's license." These days when almost everybody has something to say about Trump I hear many jokes and comments about my last name.
a playing card which is elevated above its normal rank in trick-taking games. Typically an entire suit is nominated as a trump suit – these cards then outrank all cards of plain (non-trump) suits. In other contexts, the term trump card can refer to any sort of action, authority, or policy which automatically prevails over all others.
I am an American citizen and I am determined to build a fulfilled life in freedom with a bank account that, one day, might trump Trump's. Donald Trump has no more rights than I have except that he was born here and can become a president. That is something I do not aspire to.
The word "trump" derives from "trionfi" or "triumph".
The tarot deck contains a fifth suit, known in gaming as the a-touts or honors and in occult circles as the Major Arcana, which serves as a permanent trump suit in games played with the tarot deck. The suit consists of 22 cards, including a Fool which serves as a highest trump (in Central Europe) or excuses the players from following suit elsewhere.
The Fool is the highest Trump? …now that is interesting news.
Growth can happen in strange ways. I was painting White Birds of Paradise en plein air. I packed my wooden paint box, easel and survival equipment in a backpack and looked for a natural setting to paint my desired object. Now it's getting a little hot outside, but for a while the weather was ideal to do this. I feel that painting outdoors is very spiritual, as the ceiling of the universe gives a feeling of limitless possibilities. Mostly when I go home after such sessions I am tired but I also am fulfilled, as if somebody gave me a precious gift.
I chose the White Birds of Paradise from my subconscious mind as it goes with most subjects. The events that followed were probably also designed by my subconscious mind because they surprised me. I found the flower cut off when I went a third time to capture it in oil paint. To me this was a sign that I needed to go to the studio, stay inside and paint more loose and colorful variations, especially after a client said she'd like to see this style of painting.
I made a series of large semi-abstract paintings, not knowing where I was going with the idea, but enjoying it. Somebody told me that this was the kind of work that could get me into galleries and I wanted to get into a gallery to sell my work. With high expectations of some success in this direction I called photographer Heidemarie Burke who documents all my work. I decided to get the pictures, put them in a magazine and spread the word about this new and exciting course of events.
The next day I started painting sailboats and I haven't stopped since. All the rejections from potential buyers, jobs and other forms of income made sense to me now. When doors keep closing, there is a reason. All these failings are telling me I am supposed to paint sailboats. My world immediately expanded, because this is a niche that not only has defined buyers, it has universal wisdom, romance and beauty. There are galleries devoted to this subject and I can talk easily with potential buyers about my experiences at sea. When I was young I photographed offshore races for major magazines. I am familiar with classic sailing destinations like St Malo or the Azores. It felt like a bridge between where I am and the world I feel I belong to. I am combining the art world with the world of high class adventurers.
It may sound easy and logical, but this caused a deep personal crisis. I realized that in my search to find my niche I was trying to be someone I wasn't. There were legitimate reasons why I always had rejected the idea of being a marine painter. I thought it would be boring to work from photographs, copyrights would cause trouble and there is a lot of competition. Many talented painters dedicated their whole life to marine painting. And yet, I believe I can express my own unique style painting this subject. It's expansion and I'm excited.
Where is the Michelangelo of our time?
I am following artists online who design programs for other artists on how to become wealthy. One is called The Abundant Artist. While I am watching this I think, really? There are many different ways to get attention. You can write, you can scream, you can socialize, you can laugh at everything and you can also say… I can imagine.
I started painting The Dream Weaver in Indianapolis. It was winter and every week I would haul a carload full of wood for my fireplace to keep me warm. I would grill steaks digging a path through the snow to my Weber, sometimes hip-deep. You think -20 is only a number until you have lived it.
I was also trying to figure out what the role of an artist was for myself, and in general. It was not only about me. My question was, how can I enrich the world with the richness I feel inside? Does anybody want this beautiful world? I studied great artists from long ago and from today and everywhere I found that they were rich inside, even if financially challenged. Sure, there are some artists who make it big in the world by giving the public whatever they want. Some were great at marketing. Why do you think copying Mickey Mouse paintings sell for millions?
Watching this made my stomach churn. An artist who copies another artist just to make money loses their integrity. Walt Disney invented the strip characters. Greatness does not flourish in copying a master. Greatness flourishes in imagining your own next step. The world needs authentic thinkers. Therefore to follow a person who tells you what steps to follow so you yourself can become rich and famous is ludicrous. It is already done.
Of course there are skills we artists need to learn. Marketing skills, technical skills – we all learn from the ones who were before us. That is a universal law.
The Dream Weaver is about a person weaving the dream of the tropics. I was in the Stutz Building in DownTown Indianapolis on snowy nights with the orange light shining through the ice on the windows. I was painting my dream. Now I live in the subtropics and I love it. This is where I want to be. I don't really know how I got here. (I think I drove a Penske truck.) But it doesn't matter as this is how imagination works. You visualize, you paint and the next thing you know you live it. This is how the artists of the Old World painted their vision of an airplane, of a canon, of a ship. They visualized it and then they built it on canvas and paper.
The power of an artist is unbelievable. I teach basic drawing skills only. By learning to draw you tap into the right side of the brain and you stimulate creativity.You don't have to become an artist. Our society is focused on using the left side of the brain. I don't believe this linear thinking can solve the problems we face today. The situation in the world is almost unbearable for me to watch. The destruction caused by this kind of thinking is devastating. You don't need to splash paint around to start thinking from the right side of the brain. Drawing triggers the imagination.That is all and it is powerful.
Where is the Michelangelo of our time? Where is the artist who is strong enough to stand up and create a different reality? It never is about growing polarity in politics. Creating a good life is not about politics. It is about who can create a satisfying reality for the inhabitants of planet Earth. It is the Great Master of our time who is making the path of the independent thinker who takes risks instead of trying to stay safe at a cost to others.
Hundreds of years later the drawing of the Flying Machine was picked up by the Warner Brothers, who were stimulated by the imagination of it.


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University of Massachusetts– Located at 653 Amherst Road in Sunderland, MA, North 116 Flats is located just north of the Town of Amherst and the UMass Campus and will provide 150 units of housing, including 38 units of affordable housing, to the Pioneer Valley and Five College Consortium.
The 18-acre property will consist of 150 units of 1-bedroom, 2-bedroom, and 3-bedroom units and will include an expansive 8,000 SF clubhouse complete with strength training and cardio center, yoga studio, multiple private study rooms, community spaces, and onsite leasing and management.
Outdoor amenities include green space, dog parks, outdoor fireplaces, grilling stations, and sports courts. All units will include stone countertops, faux hardwood floors, and in-unit washer/dryers.
Select units will be offered for lease as fully furnished with queen-sized mattresses and 50-inch screen TVs.


You must have visited some forums and discussion groups but they only allow you to post threads or messages but our online chat rooms Pakistani allow you to communicate with each other by fast messaging services.
Here you don't need to get yourself register because our online chat room is without registration.
If you have just joined our website then choose a nickname.
If you want to join new friends in live friendship rooms with online girls and boys then meet people here from the whole world and share your ideas with them.
Here you can talk with people in Pakistani friendship rooms on different topics. You can also invite online girls and boys here from different social networks.


In this post, we are showcasing a full list of premium Creative Travel Logo templates, that we hope will inspire you and give you ideas for creating your own travel logo or if you need a logo for your organization.
Designing travel logos is a challenge; it requires in-depth comprehension of the nature of the business that should be represented. A designer should provide a symbol that is appropriate for the nature of the business or company, like for example an image of helping fellow human being for Red Cross and an image of a chic look for a fashion industry would do the job well. Enjoy and let's go to the list!


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Opinions from the 2018 October Term
Lamps Plus v. Varela, No. 17-988: In a 5-4 opinion authored by Chief Justice Roberts, the Court reversed and remanded a decision from the Ninth Circuit and held that under the Federal Arbitration Act, an ambiguous agreement cannot provide the necessary consent for class-wide arbitration. The decision limits the availability of class-wide arbitration to contracts where it is expressly and unambiguously authorized.
Home Depot U.S.A. Inc. v. Jackson, No. 17-1471: In a 5-4 opinion authored by Justice Thomas, the Court affirmed the Fourth Circuit's holding limiting the removal of class action claims from state to federal court on the basis that neither the general removal provision of 28 U.S.C. §1441(a), nor the removal provision in the Class Action Fairness Act of 2005, permit a third-party counterclaim defendant to remove a class action claim.
Apple Inc. v. Pepper, No. 17-204: In a 5-4 opinion authored by Justice Kavanaugh, the Court affirmed the ruling of the Ninth Circuit and held that consumers who purchased apps for their iPhones through Apple's App Store were direct purchasers from Apple under Illinois Brick Co. v. Illinois and may sue Apple in an antitrust consumer class action for allegedly monopolizing the retail market for the sale of iPhone apps.
Merck Sharp & Dohme Corp. v. Albrecht, No. 17-290: In a 9-0 opinion authored by Justice Breyer, the Court vacated and remanded a Third Circuit decision and held that judges, not juries, should decide whether Food and Drug Administration actions pre-empt state court failure-to-warn class action suits on the basis of "clear evidence" the FDA would not have approved a change to a drug's label.
Nutraceutical Corp. v. Lambert, No. 17-1094: In a 9-0 opinion authored by Justice Sotomayor, the Court reversed and remanded a decision from the Ninth Circuit and held that Rule of Civil Procedure 23(f), providing a 14-day deadline to seek permission for the interlocutory appeal of an order granting or denying class certification, is not subject to equitable tolling.
Frank v. Gaos, No. 17-961: In a per curiam opinion, the Court vacated and remanded the Ninth Circuit's decision upholding a $8.5 million settlement where all net proceeds were to be distributed in a cy pres award with no direct relief to class members. The Court remanded to the courts below to address the plaintiff's standing in light of Spokeo, Inc. v. Robins.
PDR Network, LLC v. Carlton & Harris Chiropractic Inc., No. 17-1705: In a 9-0 opinion authored by Justice Breyer, the Court vacated and remanded the Fourth Circuit's decision concerning whether the Hobbs Act required the district court to accept the Federal Communication Commission's legal interpretation of "unsolicited advisement" under the Telephone Consumer Protection Act. The Court remanded to the court below to address whether the FCC's interpretation was a legislative or interpretive rule and whether petitioners had a prior, adequate opportunity to seek review.
Certiorari Decisions from the 2018 October Term
Behr Dayton Thermal Products, LLC v. Martin, No. 18-472: the Court declined to hear an appeal from the Sixth Circuit concerning whether plaintiffs may obtain issue class certification under Federal Rule of Civil Procedure 23(c)(4) without demonstrating that common issues predominate over individual issues for the entire action under Rule 23(b)(3).
Hagan v. Khoja, No. 18-1010: the Court declined to hear an appeal from the Ninth Circuit concerning a corporate issuer's duty to update its disclosures under Securities and Exchange Commission Rule 10b-5(b).
Retirement Plans Committee of IBM v. Jander, No. 18-1165: the Court agreed to hear an appeal from the Second Circuit concerning whether the "more harm than good" pleading standard can be satisfied in ERISA class actions by generalized allegations that the harm of an inevitable disclosure of alleged fraud generally increases over time.
Intel Corp. Investment Policy Committee v. Sulyma, No. 18-1116: the Court agreed to hear an appeal from the Ninth Circuit concerning whether the three-year limitations period in Section 413(2) of ERISA bars a class action suit when all relevant information was disclosed to the plaintiff by the defendants more than three years before the filing of the complaint and the plaintiff either did not read or did not recall the information.
Rotkiske v. Klemm, No. 18-328: the Court agreed to hear an appeal from the Third Circuit concerning whether the "discovery rule" applies to toll the one-year statute of limitations under the Fair Debt Collection Practices Act.
Emulex Corp. v. Varjabedian, No. 18-459: the Court in a per curiam decision dismissed the writ of certiorari as improvidently granted in this appeal from a Ninth Circuit decision concerning whether Section 14(e) of the Securities Exchange Act of 1934 supports an inferred private right of action.
2018 October Term,2018 OT,2019 Term,certiorari,class action appeals,SCOTUS,supreme court,U.S. Supreme Court
Lamps Plus, Inc. v. Varela: Class Arbitration Must Be Expressly Authorized
Questions Regarding Cy Pres Settlements Remain after Frank v. Gaos
SCOTUS Resolves Circuit Split Regarding American Pipe Tolling


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HHNM Staff
Album Reviews May 11, 2018
Rae Sremmurd's 'SR3MM' Is A Mixed Bag But It's Still Entertaining (Album Review)
By HHNM Staff / 0 Comments
Being a hitmaker is hard. Every time you release a new single it's expected to…
News & Rumors May 10, 2018
Mac Miller & Ariana Grande Have Broken Up
Mac Miller and his girl Ariana Grande have decided to call it quits, multiple outlets…
Album Reviews May 4, 2018
'Beerbongs & Bentleys' Solidifies Post Malone As a Star For Years To Come (Album Review)
If you had asked a music fan in 2015 where they thought Post Malone would…
News & Rumors February 15, 2018
Iggy Azalea's Valentine's Day Wish: Men Should Last Longer In Bed
Iggy Azalea and Tyga were the guests on special "Valentine's Day" episode of MTV TRL…
Nicki Minaj Went Off The Radar from Social Media To Reportedly Focus on New Album
Nicki Minaj's fans have been on a mission to find the rapper who has been…
Music December 28, 2017
Post Malone's 'Rockstar' Remix feat. T-Pain & Joey Badass Surfaces Online
Post Malone has truly had an incredible year. His latest single 'Rockstar' spent several weeks…
News & Rumors December 26, 2017
Cardi B & Offset Dismiss Cheating Rumors with Raunchy Instagram Live Session
Cardi B and Offset have been in the news all week, thanks to the scandal…
Album Reviews November 22, 2017
T-Pain Proves He's Still An Artist To Reckon With on New Album 'Oblivion' (Review)
T-Pain is like that friend you had in high school or college that moved away….
Album Reviews November 2, 2017
Ty Dolla Sign is Truly Unbeatable on New Album 'Beach House 3' (Review)
You have to wonder if Ty Dolla $ign will ever get the respect he deserves….


Over the past 24 hours, crypto markets have been receiving significant amounts of capital coming from fiat currencies. Global market capitalization has increased in nearly $10 billion, or about 8%, with tokens from the top 10 leading the way clearly.
Bitcoin Cash is leading the group of the top 10 cryptos by market capitalization, with a sudden surge towards 16:00 GMT that helped the project add about $500 million in just about one hour. $BCH is now up 20% in the last 24 hours.
Ethereum, EOS, Cardano and Bitcoin SV are performing strong as well. $ETH has seen its price surging over 16%, while EOS is the biggest gainer of the top coins with 22%. ADA and BSV are up over 10%. Bitcoin broke the $3900 just now.
Binance is back on $1.1b+ 24h volume.
The best performing coin of the day this far has been Veritaseum, increasing its market cap by more than 30%, followed by WAX at a certain distance, with gains of about 27%. On the other side of the table, ARK has been unable to hold all of its gains from the last days, losing almost 11% at writing time and therefore becoming the worst performing project of the day (after being the best performing one day ago).
The current bull run is serious enough as to only leave 6 projects in the red area of the table for the first 100 by market capitalization, with 3 of them being stablecoins.
Read more: WAX + ARK up 50%; ETH leads the top 10 up 10% | Is bear season over?


We are situated on 11 London Road, in a beautiful old white building close to the centre of town, opposite Northwood Estate Agents.
There is a pay and display car park (£0.60 per half hour) accessed from the opposite side of the road, a minute walk from the medical centre.
From the A414 North Orbital Rd, you can take the A1081 which merges with London Road, and continue along this heading towards the centre of town. You will find us at the far end of London Road, on the right hand side as you approach a set of traffic lights at the crossroads in the centre of town. The entrance to the pay and display car park will be on your left, just before you reach the White house, immediately after A-Plan Insurance and level with Dominoes pizza opposite.
If you leave the North Orbital Road on the A5103 then follow the road along Watling Street and then up Holywell Hill. Turn right at the traffic lights at the top of Holywell and continue down London Road for 200 meters and the White House will be on your left. The entrance to the pay and display car park is around 100m further down and on your right.
The Train station is a straightforward 20 minute walk from the St Albans Medical Centre. From the station entrance turn right and walk over the bridge down to the traffic lights at the cross-roads. From here turn left down Alma Road. At the bottom of Alma turn right at the roundabout and walk up for about 12 minutes and you will find us at the end on the right.
PLEASE NOTE: We regret that we currently have no access to for those who are entirely confined to a wheelchair. However, our staff are fully trained to assist you with any mobility needs.


Portofino has its headquarter in Guangzhou T.I.T Creative Industry Zone, which lies on the new axis of Guangzhou City. Innovation oriented and centered on the theme of premium private hotel service, Portofino adheres to the tenet of Equality, Mutual Benefit and Joint Prosperity and pursues modern high quality hotel services on the basis of diverse businesses and scientific hotel management.
Portofino enjoys favorable external environment and adopts scientific management mechanism to cultivate an enterprising and creative team of high quality professionals and management staffs, who lead and promote the strategic transformation of the hotel's profiting mode, enhance the competitiveness and added value of the hotel business and achieve perfect combination of social effect, industrial outcome and enterprise profit to make its contribution to the development of China's hotel service.


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Recruitment Officer
If you are looking for a fun, exciting and rewarding career that provides opportunity to travel, make a powerful difference in high school students' lives and are outgoing, motivated and love to sell and make a very good salary then this job is for you! Fulford Preparatory College is looking for three Recruitment Officers as we re-design our Admissions and Recruitment Department. Get in on the ground floor and help build the office, the school and a great career.
Established in 2012, Fulford Preparatory College is an international boarding school with a maximum enrolment of 60 students. We enroll students 15 to 19 years old into one of three streams: i) grade 10, 11 and 12 credits towards the Ontario Secondary School Diploma (OSSD); ii) English as a Second Language (ESL) Foundation, and; iii) University Qualification Year. Our average class size is 10 students and our graduates maintain a 100% university placement rate to their first-choice university. In addition, we offer recreational co-curricular activities and 'boutique' residential living with queen size beds and en suite bathrooms. Located in a former heritage inn in Merrickville, Ontario, previously honoured as Canada's most beautiful village, we are close to Ottawa and Brockville and are adjacent to the Rideau River and Canal system, a UNESCO World Heritage Site.
The Recruitment Officers play a hands-on critical role in the recruitment of students. Their primary function is to develop and implement strategies to sell the school to prospective boarding students and their families, recruiting mission appropriate top-quality international boarding students to the school. The ability to sell, persuade and convince individuals, (agents, educational consultants, parents, students, etc) that we offer the best educational opportunities for the student, along with the ability to build relationships quickly, a warm and endearing personality and a strategic fast thinker are all critical skills; understanding the needs and interests of the student/family/agent and then finding a way to meet those needs through the educational programing we provide. You will be responsible for market research to enhance existing markets and create new ones within your territory. You will be responsible for one of the following three territories:
Latin America and EurAsia
Meet established recruitment and enrolment targets
Set strategic direction to stay ahead of recruitment trends
Maintain existing markets and develop new ones
Research and attend fairs, maintain and develop agent contracts and develop relationships with existing parents for recruitment purposes
Working with the Marketing Coordinator, ensure you have all the necessary marketing and advertising materials required to be successful.
Provide initial contact and follow-up services as needed to students, families and educational consultants
Respond to inquiries in a prompt and professional manner
Interview and assess applicants for admission
Ensure the maintenance, accuracy and integrity of the admissions database and files
Work collaboratively within a small school community
Extensive travel to recruit in your designated territory is required
Qualifications, skills and experience:
Ability to build relationships and trust quickly, and close sales
Familiarity with the high school and/or university admission environment
Proven track record of selling, ideally educational programs and specifically private boarding schools internationally
Target and sales driven, detail and process oriented
Outstanding interpersonal and communication skills
Strong computer and technical skills
Fluency in multiple languages is an asset
University degree in business, education or related field
Only those requested to attend an interview will be contacted.
Start Date: As soon as possible
Compensation: We provide a very competitive compensation package including phone, computer (Surface), luggage for travel, breakfast and lunch daily, RRSP plan and additional pay in lieu of health benefits.
Please forward cover letter and resume to Headmaster, Kevin Farrell: kevinf@fulfordprep.com
Back to Employment Opportunities


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Tag Archives: Easter Ross archaeology
A Newly Discovered Pictish Stone for Easter Ross
by Anne MacInnes
Photographs of all 4 faces of the Conan Pictish stone © HES.
Whilst on a walk close to Dingwall, I came across a site that struck me as being slightly mysterious, atmospheric and with an air of neglect about it. I was immediately fascinated, and started to try and find out more about it.
I established that it was an early religious site, privately owned, and asked the landowner if I could have permission to survey it. This granted, and because of the difficult access, I began to form a plan of just how to carry this out. A specific parking place for one car was established and the survey began.
I followed the methodology used by Susan Kruse at Kiltearn, where I had helped carry out the survey (see blog).
First of all, three of us, sectioned off the site using tapes and this enabled me to draw up plans marking all the visible stones. They were all numbered, and then surveyed and photographed in detail. Inscriptions were carefully copied on to the recording forms, which at times involved a lot of head scratching due to the worn stone. Moss was removed but not lichen as this could damage the stone. Linda helped me almost every day, with Meryl and Beth helping when they could.
The weather was kind in the winter months when this survey was done, and we were struck by the oasis of peace, emerging wildflowers and variety of birdlife with occasional visiting roe deer. A large area of ponticum and invasive sycamore was cleared with chainsaw by Terry Doe, with Linda, Kay, and myself dragging it offsite. Finally a group of nine NoSAS members planetabled the site and did levels to show the footings and platform of a chapel, and Meryl drew this up.
The survey revealed as well as the probable chapel footings, upright headstones in various shapes and sizes, lair markers, tabletombs, graveslabs, some lightly covered by moss.
Most of them looked like this, either blank or with initials carved at the top. All the stones were orientated with their carved faces towards the east.
One day, I was brushing off leaves from a graveslab sitting on the ground, not buried, when I noticed a bit of carving that looked like a foot. Carefully removing a bit more, a leg was attached to this foot! I couldn't believe what I was seeing, so much so that I went to do something else and ignored it. However on my return it was still there and more was revealed. Continue reading →
This entry was posted in Pictish, Strathconon and Ross-shire, Surveying and Recording and tagged #SponsoraPictishStone, archaeology crowdfunding, cauldron, centaur, Class 2 pictish stone, Conan stone, crowdfunding campaign, Dingwall Museum, Double disc and Z-rod, early Christian site Easter Ross, Easter Ross archaeology, Glamis Manse, Hilton of Cadboll, hippocamp, Isabel Henderson, John Borland, Kirsty Cameron, Murthly Pictish Stone, Pictish Arts Society, Pictish carved stone, pictish cross slab, Pictish stone conservation, reuse as grave slab, Serpent and Z-rod, Shandwick stone on October 22, 2019 by nosas.
David's Fort: a Medieval Motte?
by Marion Ruscoe (NOSAS)
In around 2000 Janet Hooper, Allan MacKenzie and I undertook a survey of David's Fort, a rather enigmatic site in Balavil Wood, near Conon Bridge. Our intention was to survey the site, clarify its purpose and investigate the related documentary and contextual information. We did arrange a geophysical survey which was cancelled due to Foot and Mouth, and that was replaced with a later walkover of Balavil Wood. David's Fort itself is scheduled, but there are other features in the immediate area which may be related and which are worthy of notice.
David's Fort aerial photograph by Jim Bone
David's Fort (NH5394 5328; HER MHG8986) is essentially a large earth mound surrounded by a ditch, surrounded by an embankment. The mound and embankment were created by digging out the ditch. It's trapezoidal in shape, and the top of the mound measures approximately 80 x 85 feet. The moat is around 15 feet deep and is partially filled with water. There's no sign of any structures on the top of the mound, but these would probably have been wooden and evidence would not have survived the trees and bracken which have invaded the site.
There is a dip on the west end and a corresponding dip in the embankment with a track running down to the mediaeval road which runs from Tarradale on the Beauly Firth to the ford over the River Conon. It's been assumed that this is where the entrance was, though, since the embankment is considerably lower than the top of the mound, any bridge would either be very sloped, or mounted on a framework which raises the question "why the dip in the embankment and the very obvious path leading from that dip?" The embankment surrounding the mound has been extended for a short distance at three of the corners. The purpose of this is not clear. Water was fed into the moat via a channel leading from a lochan to the east of the site and controlled by a sluice but this channel has been damaged by the embankment which carries the power lines.
Dip in embankment, indicating possible original entry. 1998
This entry was posted in General Archaeology, Medieval, Strathconon and Ross-shire, Surveying and Recording and tagged Allanfearn monastery, Balavil Wood, Bishop Kinkell, Borgie Bridge, Conan House, Conan Mains Farm, Conon Bridge archaeology, david's fort, Dingwall Castle, Easter Ross archaeology, homestead moat, Logiebride Churchyard, medieval archaeology, moated site, motte, North of Scotland Archaeological Society, NOSAS, NOSAS report, Proncy Castle, RCAHMS, recording and surveying, Tigh Diabdh, trapezoidal structure on February 22, 2016 by nosas.


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redpajama_set_name: RedPajamaWikipedia


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Moviesr.net
Netflix Debuts 'Luckiest Girl Alive' Trailer With Mila Kunis & We Can't Wait For This Thriller!
The trailer for "Luckiest Girl Alive" is here.
Kunis, who plays the lead character from the bestselling book of the same name, says, "Ahhh-nee" not "Annie," when pronouncing her name in the trailer.
Kunis plays a former teenager named TifAni, who always felt out of place in her old money prep school. She transforms herself into Ani, "the ultimate New York City insider with a gorgeous, wealthy fiancé (Finn Wittrock), a sexy magazine job, designer clothes and the kind of shiny hair that makes other women swivel on the street," according to a description of the film from Netlix. "But, is Ani's self-proclaimed 'perfect life' really enough to numb the most painful parts of her past?"
After she's asked to participate in a documentary about a violent incident at the prestigious Brentley School that transformed her teenage years, her secret comes out.
The movie is directed by Mike Barker.
Also starring are Connie Britton as Ani's mother, "Succession" actor Justine Lupe as her best-friend, Nell; Jennifer Beals as her editor and mentor; and Scoot McNairy as a high school English teacher from Ani's past.
The adaptation of Jessica Knoll's bestselling novel will be released on Oct. 7.
[netflix] [milakunis] [movie] [thriller] [mystery] [celebrity] [actor] [hollywood] [adaptation] [trailer] [luckiestgirlalive]
'You': Joe Goldberg Becomes The Hunted In Eerie Season 4 Trailer
TV & Movies 10-Jan-2023


I do wonder if the collective thought that the pervasive ambivalence towards paying the price for stopping Hitler et al early on had substantially increased the cost ultimately paid for WW2 accounts for the willingness of our citizens to let the executive branch make those decisions. I have not found much pride taken in the fact that Americans "stood by" while outrageous actions were being pursued by Axis powers in 1939-1941.
Is it possible to find out where else you will be speaking in NY and when your various media interviews will be? I wanted very much to see your talk at Roosevelt House April 3, but it's full up, so I'll have to watch the video. I've greatly enjoyed your books.
Congratulation on your new book. I watched you talking about your new book over the weekend. You were awesome.
Re paragraph 6 and who made the sacrifices…not only our own forces but, as always, the innocent civilians in the middle. Oh how I loved 'Citizens'…sounds like the new one will answer all the questions I had in 'citizens'….WHY don't we get over there!!!!


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Mayor Turner announces Magical Winter Lights as a new sponsor for Houston's HEB Thanksgiving Parade and Reliant Energy's Mayor Tree Lighting
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Leave a Comment / Uncategorized / By Yusi An
Houston – October 27, 2016 – Mayor Sylvester Turner holds a press conference at City Hall to kick-off the 2016 holiday season by inviting Houstonians to participate in the celebration of the 67th Annual H-E-B Thanksgiving Parade and the 97th Annual Mayor Holiday Celebration and Tree Lighting Presented by Reliant, an NRG company.
On behalf of the Mayor's Office of Special Events, Mayor Turner announced this year's sponsors as well as details on what the people of Houston can expect to see at each holiday celebration.
"As my first official Holiday Celebration as Mayor of the Houston, I am privileged to be a part of such a long-standing tradition, and want to thank Reliant and all of our sponsors who have continued to make this event truly memorable."
People Generation, the producing company of Magical Winter Lights, is proud to announce that it joins a number of companies and organizations as an acting sponsor for both holiday events. HEB's Public Affairs Director, Cindy Roberts Garza took to the podium to announce Magical Winter Light's involvement in this year's Thanksgiving parade.
"[People Generation] is bringing the Magical Winter Lights float and is going to feature the multi-cultural take on the traditional holiday light show […] this new float is going to show all the different traditions we celebrate here in our city and throughout the country."
Magical Winter Lights will also partake in the Mayor Holiday Celebration and Tree Lighting Presented by Reliant an NRG company, on Friday, December 2nd. As an official sponsor, Magical Winter Lights will be participating in the annual celebration that is set to feature performances by former Destiny's Child member and Grammy-nominated singer, Michelle Williams, and electro Hip Hop Violinist and Americas Got Talent alumnus, Svet.
"The H-E-B Thanksgiving Parade and Mayor's Holiday Celebration and Tree Lighting are annual traditions for Houstonians. As Magical Winter Lights grows to become another family tradition in the Greater Houston area, we find partnering with the city on these two great events the best way to connect with the local community and the very people we are serving", said Yusi An, president of People Generation and founder of Magical Winter Lights.
The 67TH Annual H-E-B Thanksgiving Day Parade will take place downtown on November 24th at 9 a.m., and will be free and open to the public. Mayor Turner, along with grand marshals, Gold Medalists and Houstonians Simone Biles and Simone Manuel will kick off the event.
Sponsors for the Thanksgiving Day Parade include: H-E-B, Airgas, Hyatt Regency Downtown Houston, Super Bowl Host Committee, Highland Village Shopping Center, Magical Winter Lights, Wells Fargo, McDonalds, Arro App, GOYA Food, First Choice Emergency Room, Mini Piri Academy, Dickens on the Strand, SP+ Parking Kings BierHaus, and Lone Star Ford.
The 97th Annual Mayor's Holiday Celebration and Tree Lighting will be hosted with Mayor Turner and Reliant and NRG Retail President Elizabeth Killinger on December 2nd at City Hall on Hermann Square from 6p.m. to 8 p.m. The event will be open to the public.
Sponsors for the Mayor's Holiday Celebration and Tree Lighting include: Reliant (an NRG company), Cigna, Wells Fargo, Magical Winter Lights, Maggiano's, KHOU-11, the Downtown Management District and the Houston Public Library Foundation.
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Can You Afford to Buy A Home Yet?
How much are you paying in rent today? Have you considered what it would feel like to put that kind of cash towards buying your own home? Well, maybe you can.
How much are you paying in rent today?
According to a recent report, in 2019 Americans paid an average of $1,420 in rent every month. That's a lot of money.
Have you ever considered what it would feel like to put that kind of cash towards a real home? Something you own — and have equity in?
Trading in a world of rent and landlords for a mortgage and a house doesn't have to be complicated. The first (and easiest) step you can take is figuring out what it actually costs to buy a home — and whether or not you can afford one right now.
Let's kick this off by examining aspects of your financial life that affect your ability to purchase a home. Determining how much home you can afford comes down to four financial factors: Income, Savings, Expenses, and Credit.
Income: How Much Do You Make?
Basically, your recurring income establishes a baseline for how much you can afford to pay on a mortgage each month. This includes your salary and any additional payouts you receive from investments. Remember, a mortgage is a long-term commitment (usually 15-30 years), so you'll want to be confident that your income won't fluctuate for a few years while planning.
Savings: How Big Will Your Down Payment Be?
Your savings can be defined as the amount of money you have built up that can be applied to a down payment, closing costs, and other expenses.
NOTE: While you're likely to deplete the bulk of your savings with a big down payment, it's really important to not completely tap your savings. Because most mortgage lenders will want to see you have enough saved up to cover purchasing costs while still leaving some cash in an emergency fund to cover unexpected repairs or lifestyle changes.
Debts & Expenses: What Are Your Other Obligations?
What are your financial obligations each month? Are you actively paying off one or more loans?
Whether it's a monthly car payment, student loans, or your health insurance premiums, you need to tabulate exactly how much you're obligated to shell out each month before the addition of a mortgage. To assess how your mortgage might stack up against the rest of your finances, lenders like to determine your debt-to-income ratio using the 28/36 rule.
To be clear, this isn't a hard-and-fast rule. It's more of a guideline lenders use to evaluate the breakdown of a person's monthly financial obligations.
The 28/36 rule suggests any home-related expenses should never account for more than 28% of your monthly income. And, factoring in everything else, your combined debts and expenses should never exceed 36% of your pretax income.
Without question, your credit score will impact your loan rate. The amount of money you can borrow (and the rate at which you do) to buy a home is primarily affected by your combined debts and credit score. Using a sliding scale of 300 – 850, lenders typically look for a minimum qualifying score in the mid-600's. But, as your score breaks into the mid-700's, your chances of locking in a lower interest rate increase dramatically.
This is your biggest financial hurdle from a savings perspective. And, while some modern lending programs will accept down payments as low as 3% of the home's purchase price, the traditional standard down payment is 20%. Put simply, if you'd like to buy a $200,000 home, a 20% down payment would be $40,000. Again, your down payment can be less than 20%, but you'll likely have to pay "private mortgage insurance" (PMI) on top of your monthly mortgage until you cover the difference and gain equity.
Don't have 20% laying around? The option to put up a smaller down payment works for those who need a home soon, have stable income, but haven't yet had the chance to save up a nest egg for a big down payment.
Expect to pay about 3% of the home's purchase price at closing. That $200,000 home with a full 20% down payment of $40,000 will cost an additional $6,000 with closing costs. With inspection fees for pre-owned homes and property taxes, you might need to budget upwards of 5% of your home's total purchase price.
It's easy to forget this part, but you're going to need to do three things when moving: get there, furnish it, and decorate. Remember, you don't have to do this all at once. A new home doesn't mean you need all new furniture.
Back to savings — make sure you have a few months of mortgage payments stashed away before closing on a new home. You never know what could happen to your employment status.
Another piece of advice is to shop around for home loans. Nearly half of Americans don't, and data suggests that comparing just three different loans almost guarantees you a lower rate, saving you a ton of money compared to if you had settled for option 1.
Taxes vary across the board. They're set by your local county government and are based on the county's assessment of your new property. The difficult part about property taxes is they're subject to fluctuation, either by re-assessment or your local government boosting tax rates.
Unlike some apartment setups, utilities are all on you. That's a given. Where you need to pay attention is the unexpected nature of things … breaking. It's a good idea to keep a rainy day fund for bigger repair jobs. In fact, some lenders will check to see you have enough in savings AFTER purchasing the home to cover potential repairs.
Or should you just keep renting?
Most would be surprised to learn that owning a home is absolutely within their grasp. But, if you're planning a career move away from home, keep renting. Those leases typically only last a year — but, in order to avoid losing money on a home, you'll need to live in it for 2-5 years, or just long enough to regain some equity.
Also, if you map your finances, find your dream home, and determine you have "just enough" money to make it work … wait a little while longer. You'll want a cushion of cash even after the keys are yours.