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Wells Fargo makes donation to support dental practices affected by Hurricane Sandy Diverse perspectives, one mission
Treaty imposes no curbs on amalgam use
By Blog Editor On January 26, 2013 · Add Comment
By Craig Palmer, ADA News staff
The Association commended the prevention focus of the international mercury treaty approved in Geneva Jan. 19.
"Caries, the disease that causes tooth decay, afflicts 90 percent of the world's population, making this a global public health issue," said Dr. Robert A. Faiella, president of the American Dental Association. "The ADA is gratified that the treaty conditions pertaining to dental amalgam protect this important treatment option without restrictions for our patients while balancing the need to protect the environment. It is vital for people throughout the world to continue to have access to a safe, durable, affordable treatment for tooth decay."
Governments approved treaty "exceptions" to restrictions or bans for medical devices "where currently there are no mercury-free alternatives," according to the United Nations Environment Program, which convened the Geneva negotiations among more than 140 nations including the United States:
• "vaccines where mercury is used as a preservative have been excluded from the treaty as have products used in religious or traditional activities;
• "delegates agreed to a phase-down of the use of dental fillings using mercury amalgam."
Dental amalgam is not subject to any restrictions on use. Instead, the treaty calls for phasing down the need for amalgam through increased prevention and other activity. Language in ANNEX C Part II: Products subject to Article 6, paragraph 2 said, "Measures to be taken by a Party to phase down the use of dental amalgam shall take into account the Party's domestic circumstances and relevant international guidance, and shall include two or more of the measures from the following list:
• "setting national objectives aiming at dental caries prevention and health promotion thereby minimizing the need for dental restoration;
• "setting national objectives aiming at minimizing its use;
• "promoting the use of cost-effective and clinically effective mercury-free alternatives for dental restoration;
• "promoting research and development of quality mercury-free materials for dental restoration;
• "encouraging representative professional organizations and dental schools to educate and train dental professionals and students on the use of mercury-free dental restoration alternatives and promoting best management practices;
• "discouraging insurance policies and programs that favor dental amalgam use over mercury-free dental restoration;
• "encouraging insurance policies and programs that favor the use of quality alternatives to dental amalgam for dental restoration;
• "restricting the use of dental amalgam to its encapsulated form;
• "promoting the use of best environmental practices in dental facilities to reduce releases of mercury and mercury compounds to water and land."
"By phasing up global preventive strategies, we can tremendously improve oral health outcomes and by extension overall health outcomes," said Dr. Faiella, the ADA president. "Countries must make concerted efforts to raise awareness and empower healthier behaviors."
The FDI World Dental Federation and its constituency of 200 plus national dental organizations including the ADA and dental specialties and International Association for Dental Research have long supported a phase down approach to the use of dental amalgam accompanied by a "phase up" focus on preventive strategies to reduce caries, the disease that causes tooth decay. The dental organizations also support other treaty measures calling for increased research, development of alternatives to dental amalgam and best management practices that involve capturing and recycling amalgam waste.
The ADA is particularly pleased that the treaty calls for setting national objectives aimed at dental caries prevention and health promotion, Dr. Faiella said. "Long term it is critically important to raise global awareness of the importance of oral health to overall health, including how to prevent dental diseases. Doing so decreases the need for all cavity-filling and other restorative materials including dental amalgam."
The United States took part in the treaty negotiations that concluded with a fifth and final session Jan. 13-19 in Geneva. ADA observers attended the Geneva conference and other sessions convened over a four-year period to prepare a legally binding treaty to reduce mercury emissions and releases to air, water and land. The treaty text will be open for signature at an October 2013 diplomatic conference in Japan. The UNEP expects the treaty to come into force in three to five years. Initial funding "to fast track action" has been pledged by Japan, Norway and Switzerland.
"The ADA appreciates the willingness of the U.S. delegation from the State Department, Food and Drug Administration and Environmental Protection Agency to consider and be guided by the best available scientific information pertaining to dental amalgam," the Association president, Dr. Faiella, said in a statement.
The Association and a coalition of American dental organizations in a June 2012 letter to the State Department urged the U.S. negotiating team "to use the ongoing negotiations…as an opportunity to promote public health here and throughout the world."
The largest non-natural source of mercury in the environment comes from the burning of coal. The treaty also considered other sources such as small-scale gold mining and the Chlor-alkali sector. The negotiations included discussion of mercury-containing products. Based on usage, dental amalgam was last on a list of products that included batteries, measuring devices, electric switches and relays and mercury-containing lamps, meaning light bulbs.
The International Association for Dental Research participated in and contributed to the treaty negotiations, along with the FDI World Dental Federation and the International Dental Manufacturers, "and has advocated for a reduction in the use of dental amalgam (versus a ban) through increased attention to dental prevention and health promotion, increased research and development on alternatives and best management techniques for amalgam waste," said an IADR news release.
In advance of the Geneva negotiations and the treaty's ANNEX C call for "promoting research" on alternatives to dental amalgam, a December 2012 Dental Materials Innovation Workshop identified potential research priorities, according to an IADR workshop summary. The workshop was sponsored by the IADR, King's College London and FDI World Dental Federation and co-sponsored by the World Health Organization and U.N. Environment Program. Proceedings will be covered in greater detail in a scientific peer-reviewed journal, the IADR said.
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Tagged with → amalgam • curbs • imposes • Treaty

redpajama_set_name: RedPajamaCommonCrawl


This graphic is created by the NWS/NCEP Weather Prediction Center (WPC). For more detailed information, please visit the WPC Excessive Rainfall Forecast page.
In the Excessive Rainfall Outlooks, the Weather Prediction Center (WPC) forecasts the probability that rainfall will exceed flash flood guidance within 40 km (25 miles) of a point. Gridded FFG is provided by the twelve NWS River Forecast Centers (RFCs) whose service areas cover the lower 48 states. WPC creates a national mosaic of FFG, whose 1, 3, and 6-hour values represent the amount of rainfall over those short durations which it is estimated would bring rivers and streams up to bankfull conditions. WPC estimates the likelihood that FFG will be exceeded by assessing environmental conditions (e.g. moisture content and steering winds), recognizing weather patterns commonly associated with heavy rainfall, and using a variety of deterministic and ensemble-based numerical model tools.
For more information about this product, please see the documentation on the WPC website.


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President of West Nottinghamshire College's Students' Union Marc Jones (right) and vice-president Kyron Caunt (left) are pictured with Sir Vince Cable at a London college this week.
Former Minister for Business Innovation and Skills, Sir Vince, was one of the leading speakers at the NUS Shaping FE Conference at Hammersmith and Fulham college on Monday (27 March), which Marc and Kyron attended.
Sir Vince is leading a new research project for the National Union of Students called Students Shaping FE which is looking into how major reforms coming for the sector need to be tailored for students. It will also address the introduction of the post-16 skills plan and other changes to the curriculum which affects students.


If you are a mother of many, chances are you sometimes (all the time?) feel overwhelmed by all the housework there is to do. There are many ways to clean house, but here is a little tip for those of you with children.
This can be easier said than done. But here is a little secret.
Little ones are usually thrilled to help you out with something around the house!
Today I had three of my little ones clean the baseboards for me, all over the house. First, I called them all together. I had a very cheerful, upbeat tone as I said, "Look at these baseboards. They are dirty! You are very small and low to the ground, so it is easy for you to clean them. I need you to take these rags and wipe all that dirt off and make them shiny and clean. First, start in the kitchen and wipe all of those, and then go to the next room. They will look so much better!"
I had my six year old also helping, and put her in charge of making sure the littler ones finished one room before going to the next, and to also check their work (I checked it myself later too). She was happy to do this--they all were and felt like they were such a big help. They enjoyed cleaning the baseboards so much that when they were done they decided to wipe off some of the light switches and doors too. I was cleaning other things at this time, also, which encouraged them to work harder.
Check their work afterward, and if they need to do anything over again, tell them in a cheerful voice, such as, "Uh oh! You missed some over here! Come and wipe this dirt away!"
It also helps to clean alongside your children, either on the same task or something else nearby. They will be encouraged to see that Mommy is working hard to clean the house too.
Another secret: Older ones get inspired when they see how cheerfully the little ones clean and might just clean cheerfully too. My eldest was excited to do the task I gave her--which was to wipe down all the kitchen cabinets and drawers.
Do you need help with what chores to do when? I use planners such as The Confident Mom or the Motivated Moms Planner [affiliate links]. I don't have to think about what to do this way--I just go down the ready-made list and check things off when done! I assign chores to my children that they can help me with.
Remember a good attitude about cleaning is catchy. You are blessing your home and your family when you clean it, and helping your children learn this when they help you.
Hello, I think this is wonderful, I can just see the wee ones so excited to help their Momma. I wish I could make little aprons for them. I know I did train my children to help and keep the home. Now, we have three grandsons that we help teach them to keep their rooms and home clean and tidy. I tell them you want to help your Momma, because she has this whole big house to keep clean for all of you.
And they just step right up like little soldiers.


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Log Horizon Volume 4 Review
March 14, 2020 by macksamson, posted in Light Novels, Log Horizon
Last time on Log Horizon, a whole slew of people enjoyed their own beach filler episode. Meanwhile, Shiroe actually does something important and heads to the Ancient Court of Eternal Ice, a castle where the important people of Eastal, the League of Free Cities, meet to discuss political bullcrap. But first, ballroom dancing, and assorted conspiring! During all that, the twins do some combat training in the dungeon known as Forest Ragranda. While they barely manage to survive against some skeletons, Shiroe and his buddies end up… having to attend various social gatherings (disgusting!)! One night, while Akatsuki is having an existential crisis over being a loli, some Li Gan dude shows up to discuss matters with her and Shiroe. This guy is some kind of powerful Sage who knows about the different classes of magic, including some seriously OP classes that can change the entire world in a single use. The Catastrophe that caused the players to be stuck in this world is world-class magic, a World Fraction, and this is the third time it's been used. The first one involved these alv princesses from long ago who attacked mankind as revenge for their people getting wrecked, but they died too. This caused the demihumans to pop into existence, and take the world by storm. Even after creating the first Ancients, humans have been driven into a corner. Right at the end of their rope, the Second World Fraction occurred, but there wasn't enough material left to actually know what happened. But after that, the third one occurred… and here we are. Based on the time scaling, Shiroe realizes that the second World Fraction was at the time of the open beta for Elder Tales (and also, that dying can apparently cause people to lose some of their memories). Back in the forest, the kids discuss the natures of their abilities, and- poof!- finally understand the basics of playing a JRPG! And it shows too; for they have a kick-ass expedition the next day. Oh, and the people at the beach get attacked by fishmen. That's what you get for having a fanservice-y filler episode!
In this volume, the fishmen quickly end up becoming a less vexing threat than anticipated, mainly because they're accompanied by a massive army of goblins. This is an in-game event called The Return of the Goblin King. Basically, this volume is about taking out this threat.
But it's not so easy, thanks to politics. The League of Eastal has no choice but to hire the people from Akiba to fight back the goblins, but it gets complicated for some reason. It's something about "them just exploiting the Adventurers" or something. Based on this, it seems that Log Horizon is no exception when it comes to fantasy politics that waste time more than build the world of the story.
There's good news and bad news with this. The good news is that we get more character development regarding that Raynesia girl and Krusty (whom I didn't mention in the recap because I figured that she'd be written out of the series after this arc). The bad news is that it's boring. Raynesia is your typical "sheltered girl who can't do anything, but then she meets 'the one' and he shows her 'a whole new world in shining shimmering splendor' and she comes out of her shell". It's cool if you like romance, but it's not even as remotely interesting as the one player/tian relationship in Infinite Dendrogram, because those people are actual A.I., as opposed to the People of the Earth, who are humans.
At the very least, the twins and their group are now more than capable of defending themselves. The goblin battles end up going way to smoothly in this volume. I get that it's still early, but even DanMachi had more serious situations going by the fourth volume. Normally, I don't care if there is low tension, but here it felt very boring to read through for whatever reason.
One issue I've been having is that Log Horizon doesn't seem to be very good with giving its characters well-defined movepools. Sometimes, it feels like these characters have moves that they didn't even have before. The writing is still wrought with exposition, and it's getting to the point where it's describing moves that have already been established, as if we were being shown it for the first time.
Back to the low tension topic, the biggest issue with the volume is at the end. Something occurs that doesn't just ruin the tension of the arc, but ruins any sense of tension for the entire remainder of Log Horizon. As established previously, crafting-based classes can use real-world experience to make something that isn't originally programmed to exist in Elder Tales. This includes steam-powered boats, and food that actually has taste. Minor spoiler: Shiroe makes something that completely rewrites the established rules of the world, which makes him eleventy times more Kirito-ish than before, and he was already leaning far toward that extreme at this point. Sure, it's still "technically" following an established rule, but that rule now seems to serve toward justifying any number of Deus ex Machinas that could occur moving forward. Plus, it undermines the worldbuilding that served as Log Horizon's greatest source of appeal.
Holy crap, these scores have been degrading over time. It's now almost as low as my final score for Overlord… which I recently dropped. Things are not looking good on the horizon (no pun intended). Let's see, the next volume's called… Sunday in Akiba? Oh… that sounds like filler. Eff me.
Tagged dialogue, exposition, fantasy, human, light novel, Log Horizon, politics, post apocalyptic, realistic, sci-fi
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Convert Windows .NET Framework / WinForms C# App to a .NET CORE Website / Web Portal on Linux Ubuntu Server with a Few Additions, Logic Changes for Web, Admin Panel and Payment Portal for Subscriptions with Access Control and User Profiles.
I would like to convert my Windows C# .NET / WinForms App t0 run as a .NEW Core Web Portal / WebSite on Linux(Ubuntu).
My App is not very large or complex, but will need a few things added, like a Payment options to access it. For Payment, I will be using PayPal, I also would like to accept BTC and maybe others like WeChat, if able.
There needs to be a way to Check that the Payments where successful, before access is given! Also know if someone Canceled to end their access on time and if someone charges back, to end their access right away!
There will be 3 Subscription models; Basic Sub, Super Sub, VIP Sub; Each will have Permissions to access different Portals / Pages.
Need to add User profiles(Registration).
After They Make a Payment and Become a Subscriber, They will be able to add There "ID", Then it LOCKs and They can ONLY Change it Once every 30 days. When Their Sub Expires they lose all access, until they Pay again.
Right now, this App uses data from Flat files, and those files get updated by another App, within this App.
I will need those flat files and updates to now go to an SQL Server and Data now pulled from there.
Sometimes the data updated is in bad format, you might need to fix the RegEx and you will need to have a way to check & fix those bad lines of input when syncing with SQL. eg. sometimes a field is missing or a ' or " is added from the data, which changes the string logic, small things like that.
An Admin Portal is a MUST! Here I can Run the Data update App or do any Importing, Backup of DB and all that Normal Admin Panel type stuff. Also be able to Edit user profiles, Payment time, Payment options, All Payment Stuff. Some Tabs/Pages Will not be accessible for all users, so I will need Permissions per Page / Tab Maybe like 3 Layers of Subscription Access and Then an Admin Access Level(See All). I Expect this Admin Portal to be Amazing! Have all I Listed and Much more! This is a very critical thing.
Most of the Logs, Output and Errors will need to be shown on the site to the users, like they show in the App, but might need to add more to make it look better and transforms the errors that close the App to display the error message.
If a User leave the site or changes the page there should be a tab or place where they can see the logs or better yet, right there on the same Page / Tab they started the App from.
Everything should keep running for the Users, even if they have closed their browser or got logged out from no action on the Website. - Maybe save the logs in the Database (last 50 - 100) log outputs, then they can view those, other and better ideas on how we could do this are welcome.
Users Will Need a STOP Button, for when they are Running a Long Test and they need to STOP it for any reason; Maybe something like a STOP check before each Loop or Run. Open to more ideas on this, but it's Very Critical.
I would like to turn one of the App Pages into using a Task List, Where you can queue a few different Script Options to Run, one after another. So when you click Start, it will add it to a Task List and Run from that list. When / If you STOP the runs, it will Clean the List and Tasks.
Would like to Organize the Drop-Down List that is created by the Values in the DB, Maybe have then in Groups and Have Options in the Admin List to add a HIDE feature, where some Items are NOT on the Drop-Down List to Choose From.
If you are NOT 100% sure that you can complete this to my 100% satisfactory, Please do NOT place a bid.
I MUST be 100% satisfied and things must be running correctly for this project to be completed and Payments released.
I could convert from .net to .net core but your budget is low with your requirement. Relevant Skills and Experience ASP.NET Core 2.1, C# and SQL Server Proposed Milestones $250 USD - Need to increase budget.
Hello Sir, I have read your requirement and we will happy to work on this project. Stay tuned, I'm still working on this proposal.
Please consider me to work with you. I have years of experience in making sure application is scalable, not merely a copy of existing code.


If you want to start your own business yet you do not know where to actually start then why not consider investing in a BBQ and grill cleaning business in Maine? Do not hesitate about how you can potentially earn from this type of business because it does not entail any high startup cost nor does it require years of experience to be able to grow one. All you need is patience and hard work to be able to reach out to residents within Maine and you are good to start.
Remember that we are not a franchising business which means that you do not have to pay monthly or annual royalty fees. We have also been receiving a lot of service requests from residents in Maine in the past but we are having a hard time reaching out to all of them. We need you to help us market this service to clients who are willing to pay for BBQ and grill cleaning services. You can work at your own hours too and charge fees according to the services you render. We will assist you as you start your BBQ and grill cleaning business and ensure that we will walk you through the entire process throughout your business' lifetime.
Why Start a BBQ Cleaning Business in Maine?
Weather is Great for Outdoor Grilling: Maine is known for having comfortable summer climates. This allows flexibility when desiring to grilling food outdoors. Likewise, winters are not too cold which means that there is potential to offer your grill cleaning services all-year long.
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Talk to us today to find out more about this stellar BBQ cleaning business opportunity in Maine!


Items where Subject is "Medicine > Max von Pettenkofer-Institute"
Fingerle, Volker; Pritsch, Michael; Wächtler, Martin; Margos, Gabriele; Ruske, Sabine; Jung, Jette; Löscher, Thomas; Wendtner, Clemens; Wieser, Andreas (2016): Candidatus Borrelia kalaharica Detected from a Febrile Traveller Returning to Germany from Vacation in Southern Africa.
Zhong, Yu; Anderl, Florian; Kruse, Tobias; Schindele, Franziska; Jagusztyn-Krynicka, Elzbieta Katarzyna; Fischer, Wolfgang; Gerhard, Markus; Mejias-Luque, Raquel (2016): Helicobacter pylori HP0231 Influences Bacterial Virulence and Is Essential for Gastric Colonization.
Funk, Christina; Ott, Melanie; Raschbichler, Verena; Nagel, Claus-Henning; Binz, Anne; Sodeik, Beate; Bauerfeind, Rudolf; Bailer, Susanne M. (2015): The Herpes Simplex Virus Protein pUL31 Escorts Nucleocapsids to Sites of Nuclear Egress, a Process Coordinated by Its N-Terminal Domain.
Spriewald, Stefanie; Glaser, Jana; Beutler, Markus; Koeppel, Martin B.; Stecher, Bärbel (2015): Reporters for Single-Cell Analysis of Colicin Ib Expression in Salmonella enterica Serovar Typhimurium.
Bergström, Joakim H.; Berg, Katarina A.; Rodriguez-Piñeiro, Ana M.; Stecher, Bärbel; Johansson, Malin E. V.; Hansson, Gunnar C. (2014): AGR2, an Endoplasmic Reticulum Protein, Is Secreted into the Gastrointestinal Mucus.
Kakoschke, Tamara; Kakoschke, Sara; Magistro, Giuseppe; Schubert, Soeren; Borath, Marc; Heesemann, Jürgen; Rossier, Ombeline (2014): The RNA Chaperone Hfq Impacts Growth, Metabolism and Production of Virulence Factors in Yersinia enterocolitica.
Maier, Lisa; Barthel, Manja; Stecher, Bärbel; Maier, Robert J.; Gunn, John S.; Hardt, Wolf-Dietrich (2014): Salmonella Typhimurium Strain ATCC14028 Requires H-2-Hydrogenases for Growth in the Gut, but Not at Systemic Sites.
Maier, Lisa; Diard, Médéric; Sellin, Mikael E.; Chouffane, Elsa-Sarah; Trautwein-Weidner, Kerstin; Periaswamy, Balamurugan; Slack, Emma; Dolowschiak, Tamas; Stecher, Bärbel; Loverdo, Claude; Regoes, Roland R.; Hardt, Wolf-Dietrich (2014): Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis.
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Pogoda, Madlen; Bosse, Jens B.; Conzelmann, Karl-Klaus; Koszinowski, Ulrich H.; Ruzsics, Zsolt (2014): A Modified Screening System for Loss-of-Function and Dominant Negative Alleles of Essential MCMV Genes.
Pham, Kieu Thuy; Weiss, Evelyn; Jiménez Soto, Luisa F.; Breithaupt, Ute; Haas, Rainer; Fischer, Wolfgang (2012): CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL.
Stenkova, Anna M.; Isaeva, Marina P.; Shubin, Felix N.; Rasskazov, Valeri A.; Rakin, Alexander V. (2011): Trends of the major porin gene (ompF) evolution. Insight from the genus Yersinia.
Uliczka, Frank; Pisano, Fabio; Schaake, Julia; Stolz, Tatjana; Rohde, Manfred; Fruth, Angelika; Strauch, Eckhard; Skurnik, Mikael; Batzilla, Julia; Rakin, Alexander; Heesemann, Jürgen; Dersch, Petra (July 2011): Unique cell adhesion and invasion properties of Yersinia enterocolitica O:3, the most frequent cause of human Yersiniosis.
Yoo, Jaehyuk; Kang, Jinjoo; Lee, Ha Neul; Aguilar, Berenice; Kafka, Darren; Lee, Sunju; Choi, Inho; Lee, Juneyong; Ramu, Swapnika; Haas, Jürgen G.; Koh, Chester J.; Hong, Young-Kwon (2010): Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus.
This list was generated on Sun Apr 21 20:49:01 2019 CEST.


text:
The extension project of Roissy must be revised in depth, according to Djebbari
The minister for Transport considers that because of the crisis of the Covid-19, this project provides for the reception of 40 million passengers more "no long
30 July 2020 Thursday 17:57 - 62 reads.
The minister for Transport considers that because of the crisis of the Covid-19, this project provides for the reception of 40 million passengers more "no longer justified".
The mega-project expansion of terminal 4 at Roissy-Charles de Gaulle airport, with a capacity of 40 million annual passengers, will be there on the day ? What was the flagship project of the group Aéroports de Paris (ADP) "shall be revised in depth", due to the crisis related to the Covid-19, considered this Tuesday by the minister for Transport Jean-Baptiste Djebbari, on Europe 1.
"The project of the T4 needs to be reviewed in depth," he said, when asked about the necessity of this extension, as the manager of the parisian airports, has announced a return of traffic to pre-crisis levels only between 2024 and 2027, due to the brutal shock of the crisis of the sars coronavirus. "An in-depth review, this means that the project which provided for the home at 2030 from 40 million passengers in more, probably today is no longer justified as it was expected," he said.
Reviews on environmental
"however, there will need accommodations, there will be a need to accommodate new types of traffic, there will need to continue to be able to construct soberly according to the needs of those of the platform," the minister continued. "We are currently investing heavily in the aircraft to hydrogen, we need to develop airport capacity to accommodate the aircraft to hydrogen", he also said.
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For ADP, the objective of the future terminal is to accommodate the attendance of Roissy airport, second airport in Europe behind Heathrow. But this project, at a cost estimated to be between 7 billion and 9 billion euros, has been criticised for the environmental plan. In an opinion rendered at the beginning of July, the environmental Authority (EA) noted that "the equation to solve" between the increase of flights, road traffic, and the respect of the international goals of France in terms of reduction of gas emissions greenhouse effect "is not described nor asked in a comprehensive way".


Slow cooked British beef and British pork, tomatoes, herbs and Chianti, layered with free range egg pasta and a creamy béchamel sauce, topped with a sprinkling of parmesan cheese to finish.
British Beef (17%), Cooked Free Range Egg Pasta (15%) (Durum Wheat Semolina, Free Range Egg, Water, Free Range Egg White), Cows' Milk, British Pork (10%), Tomato (10%), Single Cream (Cows' Milk) (7%), Passata (7%), Onion, Tomato Purée, Chianti Red Wine (3.5%), Parmigiano Reggiano Cheese (Unpasteurised Cows' Milk), Carrot, Mushroom, Garlic Purée, Cornflour, Extra Virgin Olive Oil, Fortified British Wheat Flour (Wheat Flour, Calcium Carbonate, Iron, Niacin, Thiamin), Red Wine Vinegar, Butter (Cows' Milk), Salt, Rosemary, Brown Sugar, Wheat Flour, Oregano, Black Pepper, White Pepper, Porcini Mushroom Powder, Bay.
Produced and packed in United Kingdom using British beef and pork.


03:25:39 <mbalho> rvagg: would it make sense to have levelup and/or leveldown return backpressure in write streams when a put/batch is larger than the write buffer size?
03:49:26 <rvagg> sounds like you need to increase your writebuffer size then!
04:08:26 <ryan_ramage> can I emit more than once for a document?
05:06:59 <ryan_ramage> can the createIndexedStream take a start and end key?
21:48:00 <mbalho> kenansulayman: what are the implications of the background-pause thing for node?


Dear moderator where is Dr Tui?
Dr R Basu, could you help please?
Not producing enough milk for 4 month old baby. What remedies to help?
PE & ED is a common issue for men. Between 40%-50% have it at some time in their life.


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Increasing consumer awareness of food safety issues requires the development of highly sophisticated techniques for the authentication of food commodities. The food products targeted for falsification are either products of high commercial value or those produced in large quantities. For this reason, the present investigation is directed toward the characterization of coffee samples according to geographical origin attributes. In addition, the current examination is focused on the identification of particular marker compounds that compose the volatile and semivolatile aroma fraction of flavoured and dessert coffees. The conducted research involved the development of a rapid headspace solid phase microextraction (HS-SPME) – gas chromatography – time-of-flight mass spectrometry (GC-TOFMS) method for the verification of geographical origin traceability of coffee samples. As opposed to the utilization of traditional univariate optimization methods, the current study employs the application of multivariate experimental designs to the optimization of extraction-influencing parameters. Hence, the two-level full factorial first-order design aided in the identification of two influential variables: extraction time and sample temperature. The optimum set of conditions for the two variables was 12 min and 55 oC, respectively, as directed by utilization of the Doehlert matrix and response surface methodology. The high-throughput automated SPME procedure was completed under optimized conditions by implementing a single divinylbenzene/carboxen/polydimethylsiloxane (DVB/CAR/PDMS) metal fiber with excellent properties of durability, which ensured the complete analysis of coffee samples in sequence. The coffee sample originating from an authentic Brazilian coffee producing region and characterized by rich volatile and semivolatile chromatographic profiles was selected as a reference starting point for data evaluation. The combination of the retention index (RI) system using C8-C40 alkanes and the mass spectral library search was utilized for the confirmation of analyte identity in this reference sample. Twenty-nine volatile and semivolatile compounds selected across the wide range of GC chromatogram were then evaluated in terms of chromatographic peak areas for all samples that are to be submitted to this classification study. The semiquantitative results were submitted to statistical evaluation, namely principal component analysis (PCA) for the establishment of corresponding geographical origin discriminations.


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by Apollonia Kang | Feb 12, 2019 | Blog
Asian American Therapy
Data show that although the Asian community demonstrates strong needs for mental health services, going to therapy is often not considered as an option. As a therapist who grew up in China and now lives in the U.S., I would like to share some insights about the myths contributing to the underutilized mental health services among Asians, and why Asians could benefit from therapy.
The stigma about mental health is still prevalent today. A commonly held belief I grew up with is that you are crazy or there must be something wrong with you to seek therapy. Being in therapy definitely doesn't mean there's something "wrong" with you. In addition to seeking therapy for the treatment of specific disorders, many people who do not necessarily meet any diagnostic criteria are also entering therapy nowadays for personal growth. They take the initiative to explore their identities, strive to gain insights about their relational patterns, and develop the tools to be their best selves.
The avoidance of discussing one's emotional life is prominent in Asian culture. Most Asian parents praise values such as "perseverance", "sacrifice", and "hardworking", and associate the expression of emotions and vulnerabilities as weakness. Moreover, because Asians are often subject to the stereotype of "model minority", many of us feel the immense pressure to prove ourselves and live up to that reputation. For Asian men in particular, verbalizing one's vulnerability stirs up feelings of shame, and they end up suppressing their feelings and stay silent on what bothers them. However, when emotions are not accepted, validated, and addressed in healthy ways, people may develop destructive habits to relieve the pain from bottling up, such as addiction, stonewalling, and hurtful communication, further deteriorating our mental health. Even if our families and friends are trustworthy, we may not feel entirely comfortable revealing everything, fearing that the information might spread through gossip, or that we may be judged and criticized. That's where therapy comes in, as therapy is private and confidential. Therapists aim to provide a safe space for the exploration of difficult and overwhelming feelings, so we nip psychological disorders in the bud, so to speak.
Cultural values are also at play when it comes to seeking therapy. Many Asians consider talking to a stranger about emotional issues as airing their dirty laundry. "Saving face" is an imperative driving force behind the avoidance of therapy. However, the efforts to hide one's emotional and relational issues may worsen the situation, causing more maladaptive behaviors to manifest. Therapy helps us accept that setbacks, failings, conflicts, frustrations, losses, etc., are integral parts of life, and do not imply defeat or flaws. I've seen couples who arrive in therapy too late, as a last-ditch effort to save their relationships. If we can address the tensions and conflicts in their early stages, we have a better chance of rekindling the partnership. Don't wait till things get out of control to ask for help.
Looking for a therapist who can understand your cultural values, and preferably speak your native language could ease the discomfort of being in therapy for the first time. I empathize with the hesitation and struggles when it comes to seeking support. That's why I am passionate about reducing the stigma about mental health and providing therapy in both English and Chinese to empower diverse populations.
Please call me for an Initial Consultation at 312.880.9656.


A troubled U.S. Army officer (Denzel Washington) is ask to review the posthumous candidacy of the first woman (Meg Ryan) to receive a Medal of Honor. During the investigation, he finds himself plunged into an apparent cover-up surrounding her death - and must confront his own tormenting demon in the process.
Reviews for "Courage Under Fire"


Did you know that you can pay 45 Euro for a simple basic shirt? Me, I was surprised. And sort of shocked. Because I really need 5 to 10 shirts right now.
And, yes, at last I found a lot of the cheaper version.


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FOR BOOKING AND INFORMATION, PLEASE CONTACT GARY BIVONA AT 561-212-0339 OR BIGTIMETRIBUTES@HOTMAIL.COM. OR, YOU MAY CLICK HERE TO GO TO OUR CONTACT PAGE.
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NEVER STOP BELIEVIN'
has been rocking stages all over the U.S. and beyond since its inception in 2008. Venues such as Florida's Meyer Amphitheater, Hollywood ArtsPark Amphitheater, Digital Domain Stadium, Roger Dean Stadium and the Daytona Beach Bandshell have recognized NEVER STOP BELIEVIN' as the premiere tribute to Journey, drawing record crowds and delivering hit after Journey hit with unmatched passion, precision and finesse. The band has also traveled far and wide to places such as Santo Domingo, Honduras, Trinidad, Georgia, Louisiana, Michigan, New York, Texas, and Virginia Beach for special shows at historic theaters like the Calumet Theater in Michigan's upper peninsula. Based in South Florida, NEVER STOP BELIEVIN' has the incredible privilege of working with the incomparable Billy D. Lindley on lead vocals, as featured in the video above. Lindley puts his heart and soul into his delivery as Steve Perry in his full regalia and 80's San Francisco splendor. Backed by band members Gary Bivona (keyboards, vocals, musical director), Clint Ettorre (guitar, vocals), Kam Falk (bass, vocals) and Steve Quinto (drums), NEVER STOP BELIEVIN' brings both the look and sound of Journey in their prime years to each and every show, complete with five-part vocals. Don't miss the extraordinary musicianship and showmanship of NEVER STOP BELIEVIN'.
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You find it safe and not a bit threatening to regard your life as it now stands to be focused on arranged and hoped-for outcomes. You have "arranged" to formal teaching for at least another three years, have given little or no thought to how long you'll maintain your private workshops, can't see your way to returning to the Santa Barbara Writers' Conference after changes in its ownership and management visions; your approach to individual lectures or presentations is pragmatic.
There are at least four books you wish to write, thus each of those projects has a hoped-for outcome, to which you add the hoped-for outcome of their publication.
In addition, there are hoped-for outcomes related to living arrangements, health, recreation, study, times with friends, times related to musical events, splendid meals, and a broad, undifferentiated spectrum of outcomes that land indiscriminately on your fancy, much as a mosquito chancing on your arm of a summer's evening.
Beyond all these is the hoped-for outcome of improvement in your craft as a writer, as an editor, and as a teacher.
These hoped-for outcomes or goals are not the entire sum and substance of you at the moment, but they do represent a significant picture of what you are now, on October 16, 2012, if not a significant picture of who you are. Along those lines, you like to think of yourself as a work in progress.
No surprise that such goals and projected or hoped-for outcomes are useful informants when the time comes for you to create characters for your own work or approach the analysis of the characters of other writers in the matter of your teaching, book reviewing, and other nonfiction writing.
Somewhere in the computation of why and what you are, what you think and why you think it, how you write and why you write it, there is a disconnect. You've thought and written about this disconnect before.
When you consider the men, women, and in-betweens you've followed as a loving and trusting reader, you are reminded how their creators, their authors, sent you beyond your comfort zones by making worse consequences than you could have imagined. The unthinkable had come to pass. This neither means nor intends unthinkable events are the exclusive province of story; the unthinkable often makes its presence in real life, shifting, often shattering the lives of those it effects.
Story thus moves you beyond your tolerance for accepting the downward arc of the hoped-for, makes you better able to peer directly into the eyes of the unthinkable as it approaches you in the Trader Joe's parking lot, wanting to know if you've got any spare change. Story has given you a menu of unthinkable things happening to individuals you in some ways know better than you know real, live persons.
Story, as you encounter it and taste of it and feel yourself grow from it, challenges you to bring better, more intense unthinkables to the characters you create, not to fill some temporal standard or dramatic convention but instead to help yourself and, perhaps, some unseen reader accept the real fiction that your story is fiction.
In some ways, particularly sexual, fantasy is about gratification. You're comforted to see that many of your fantasies, in particular the sexual ones, move toward partnerships, mutuality, regard for another. To that extent, fantasy could be seen as an accurate index of one's==your—depth as an individual.
To the extent that dreams and hoped-for outcomes are fantasy, let those dreams and hopes and fantasies focus on the unthinkable as the object to be transcended. Whether we get to the unthinkable and conquer it, or it wags its finger at us and says, Sorry, kid, not this time, we are not settling for the easy out. We are saying we are in life and in story to win.


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Yes, our sales team can provide official quotes for you.However, you must first specify the billing address, shipping address, e-mail address, phone number and shipping method. We cannot create an accurate quote without this information.
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We can ship your order through FedEx, TNT, DHL, or EMS on your account or prepayment. We also ship"freight collect" against your account. You will receive the goods in Next Day, Two Day, or Three Days for domestic shipments, while international shipments typically take shipping companies a few business days to deliver. For items that are not in stock, the delivery schedule will vary based on the item.Please contact our sales team to inquire whether a material is in stock.
We accept purchase orders from customers that have acredit history with us, you can fax, or email the purchase order to us. Please make sure the purchase order has both the company/institution letterhead and authorized signature on it. Also, you must specify the contact person, shipping address, email address, phone number, shipping method.
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According to every specific orders, we will discuss with customer about the suitable payment method, cooperate with each other to better complete the transportation and related transactions.


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Frisk v. Cannon
Court Supreme Court of Minnesota (US)
Writing for the Court PER CURIAM.
Citation 110 Minn. 438,126 N.W. 67
Decision Date 22 April 1910
Parties FRISK v. CANNON & BALCOME et al. SAME v. BALCOME.
110 Minn. 438
126 N.W. 67
CANNON & BALCOME et al.
BALCOME.
Supreme Court of Minnesota.
Appeal from District Court, Ramsey County; Grier M. Orr, Judge.
Action by Hulda E. Frisk against Charles M. Cannon and F. E. Balcome. Verdict for plaintiff as against defendant Balcome, and in favor of defendant Cannon. From the judgment, defendant Balcome appeals; and from the order dismissing the action as to defendant Cannon, plaintiff appeals. Order and judgment affirmed.
Plaintiff was placed by one of defendant physicians on an insulated platform, a conical cap was put above and in front of her head, and electricity was caused to be discharged by a static machine through the cap upon plaintiff's head. Defendant left the room. No attendant was present. Plaintiff's head was seriously burned. It is held that actionable negligence on part of defendant was shown.
[126 N.W. 67]
Richard & Coe, for appellant Frisk.
C. D. & R. D. O'Brien, for appellant Balcome.
PER CURIAM.
Plaintiff and appellant charged the defendants and respondents, as partners engaged in the practice of medicine, with having negligently treated plaintiff with static electricity, to her injury. It was alleged: Plaintiff was placed on an insulated platform connected with the electrical machine. Above and in front of her head was put a conical cap, in a position subsequently described in detail. Static electricity was caused to be discharged from the machine, through the cap, in, upon, and through plaintiff. Defendant then left the room. No attendant was present. After the lapse of eight or ten minutes, plaintiff screamed. Defendant immediately entered the room, and discovered that her head was smoking. Through the negligence of defendant a large portion of the top and sides of plaintiff's head was seriously burned, whereby she was damaged in the sum of $5,000. Defendant admitted the fact of burning, but denied negligence. The case was tried to a jury, which returned a verdict of $1,200 for plaintiff. This appeal was taken from judgment entered against defendant Balcome.
Plaintiff made out a prima facie case of negligence. Plaintiff's only expert testified that, if the cap were brought close to the
head and there was volume enough, there would be a continuous spark and harm would result. His testimony to the effect that the distance the cap was placed from plaintiff's head would determine whether a burn was likely to occur, together with the testimony of plaintiff that it was not adjusted as on former occasions, and also the conduct of defendant in leaving the plaintiff in the room unattended, while the machine was working, for the space of ten minutes, during which time the burn occurred in connection with the other evidence in the case, was sufficient to take the question of defendant's negligence to the jury.
The trial court was justified in concluding that defendants were not partners, and that defendant Cannon was not liable for the negligence of defendant Balcome.
Order and judgment affirmed.
O'BRIEN, J., took no part.
JAGGARD, J.
I respectfully dissent. The evidence in my opinion rebuts the inference of negligence, to which it may be conceded the circumstances gave rise. It appears that this plaintiff had been subjected to the same treatment by the same machine on seven or eight previous occasions without harm. Defendant called a number of well-known experts of the highest character. The effect of their testimony is:...
Whitmore v. Herrick, No. 38636.
...Curtis on Electricity, § 597; San Juan Light & Trans. Co. v. Requena, 224 U. S. 89, 32 S. Ct. 399, 56 L. Ed. 680;Frisk v. Cannon, 110 Minn. 438, 126 N. W. 67; 2 Jones on Evidence, § 184, pp. 182 and 183; Johnson v. Marshall, 241 Ill. App. 80;Loveland v. Nelson, 235 Mich. 623, 209 N. W. ......
Whitmore v. Herrick, 38636
...on The Law of Electricity, Section 597; San Juan L. & T. Co. v. Requena, 224 U.S. 89, 56 L.Ed. 680, 32 S.Ct. 399; Frisk v. Cannon, 110 Minn. 438 (126 N.W. 67); 2 Jones Commentaries on Evidence [205 Iowa 624] (1913) 182, 183, Section 184; Johnson v. Marshall, 241 Ill.App. 80; Loveland v.......
Prewitt v. Higgins
Court of Appeals of Kentucky
...negligence either in selecting or administering the treatment. Miller v. Blackburn, supra; Sweeney v. Erving, supra. Cf. Frisk v. Cannon, 110 Minn. 438, 126 N.W. 67, 28 L. R. A. (N. S.) 262. Injury may result from the use of the drug even when the doctor has proceeded with the utmost care a......
United States State Supreme Court (Kentucky)
...negligence either in selecting or administering the treatment. Miller v. Blackburn, supra; Sweeney v. Erving, supra. Cf. Frisk v. Cannon, 110 Minn. 438, 126 N.W. 67, 28 L.R.A. (N.S.) 262. Injury may result from the use of the drug even when the doctor has proceeded with the utmost care and ......


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Globally Recognized Multiple Sclerosis Expert, Dr. Lawrence "Larry" Steinman, Joins Trethera Scientific Advisory Board
25th May 2021 /in News /by Trethera
Los Angeles, May 25, 2021 —Trethera Corporation (Trethera), a biopharmaceutical company committed to developing novel drugs targeting cellular nucleotide metabolism for the treatment of cancers and autoimmune diseases, is pleased to announce the appointment of renowned autoimmunity researcher Dr. Larry Steinman to its Scientific Advisory Board. Dr. Steinman will be advising Trethera regarding TRE-515 development, a first-in-class compound with the potential to treat multiple sclerosis (MS) and other autoimmune neurologic diseases.
Dr. Steinman is currently a professor of Neurology and Neurological Sciences, Pediatrics, and Genetics at Stanford University and leads a research team focused on autoimmune diseases. He is a recipient of numerous honors and awards, including the John M. Dystel Prize awarded jointly by the National Multiple Sclerosis Society and the American Academy of Neurology for his research on MS, the Charcot Prize for Lifetime Achievement in MS research and the Cerami Prize for Translational Research. Dr. Steinman is also a member of both the National Academy of Sciences, and the National Academy of Medicine. Dr. Steinman coauthored the groundbreaking 1992 Nature article describing Tysabri, a multiple sclerosis and Crohn's therapeutic now approved in over 80 countries and taken by over 200,000 MS patients.
"We are honored and proud to have Dr. Steinman's expertise and inputs with our Scientific Advisory Board," said Dr. Ken Schultz, Trethera Chairman and CEO. "He is a leading authority on autoimmune diseases, with over 40 years' experience treating and researching MS. He joins us at a pivotal period, as we migrate from our preclinical proof-of-concept data and FDA Orphan Drug designation, into clinical development planning. Dr. Steinman's expertise will be invaluable to our efforts to establish TRE-515 as a treatment option for patients fighting this debilitating disease."
"I came to Trethera initially skeptical that TRE-515 could bring value to multiple sclerosis patients beyond the available therapeutic options," said Dr. Steinman. "However, I was won over by the compelling data presented combined with the world-renown team Trethera has put together to advance this work. I am convinced that TRE-515 has the potential to positively impact MS patients and am excited to work with the team as this compound progresses toward the clinic."
Reference: Nature, March 5, 1992, Volume 356.5
About Trethera
Trethera is a preclinical stage privately held biopharmaceutical company dedicated to pioneering the development of novel treatments for autoimmune diseases and cancers. Founded by prominent UCLA scientists, Trethera is led by experienced management and board members.
Trethera's innovative approach to targeting nucleotide metabolism led to the development of TRE-515, an orally taken capsule designated by the FDA as an Orphan Drug. TRE-515 is a first-in-class preclinical stage drug that inhibits deoxycytidine kinase (dCK), the rate-limiting enzyme in the nucleoside salvage pathway, one of two biosynthetic pathways that generate DNA precursors. It is believed that some forms of cancer may be preferentially dependent on the salvage pathway to support tumor growth. Certain autoimmune diseases might respond to TRE-515 treatment. Trethera is developing TRE-515 for use as a monotherapy or in combination, to precisely target a metabolic vulnerability of cancer cells or autoimmune diseases that will transform outcomes for patients.
Note on Forward-Looking Statements
All statements other than statements of historical facts included in this press release that address activities, events or developments that Trethera believes or anticipates will or may occur in the future are "forward-looking statements," which may often, but not always, be identified by the use of such words as "may," "might," "will," "will likely result," "would," "should," "estimate," "plan," "project," "forecast," "intend," "expect," "anticipate," "believe," "seek," "continue," "target" or the negative of such terms or other similar expressions. Although Trethera has a reasonable basis for the forward-looking statements contained herein, Trethera cautions that such statements are based on current expectations about future events and are subject to risks, uncertainties and factors relating to medical and scientific research, all of which are difficult to predict and many of which are beyond Trethera's control, that may cause actual results to differ materially from those expressed or implied by the forward-looking statements in this press release. These potential risks and uncertainties include, without limitation: the extent to which development of any novel cancer therapies or therapies for autoimmune diseases succeeds; whether Trethera would obtain the necessary regulatory approvals to commence human trials or commercialize TRE-515 or any novel therapies resulting from such research; Trethera successfully implementing its growth strategy, including that relating to its disease therapies; the effects of the global Covid-19 pandemic; changes in economic conditions; competition; and risks and uncertainties applicable to the business of Trethera. The statements in this press release speak only as of the date hereof and Trethera does not undertake any obligation to update, amend or clarify these forward-looking statements whether as a result of new information, future events or otherwise. The Company intends that all forward-looking statements be subject to the safe-harbor provisions of the Private Securities Litigation Reform Act of 1995.
https://www.trethera.com/wp-content/uploads/2015/12/trethera_logo-wo.png 0 0 Trethera https://www.trethera.com/wp-content/uploads/2015/12/trethera_logo-wo.png Trethera2021-05-25 00:25:002021-12-14 17:04:27Globally Recognized Multiple Sclerosis Expert, Dr. Lawrence "Larry" Steinman, Joins Trethera Scientific Advisory Board


The main driver of the UK economy is London and its knock on effect in the surrounding South East of England. This is one of the few parts of UK that earns more income than it spends. The current and future world income generators are the big international cities – London, New York, Shanghai, Hong Kong, Singapore etc. etc. They are clusters of high value added service industries supporting the regional management of large multinationals with such things as financial services, legal services, management consulting, marketing, advertising and recruitment. They attract massive international investment and provide talented and educated people with highly paid jobs. This creates wealth which trickles down to workers in the supporting industries and services. Edinburgh is not a major international city, nor a major European city. Neither is Glasgow. There can only be one regional hub and currently that crown belongs to London, making the creation of a second hub nearby very difficult. Do the Scottish Nationalists have a detailed plan as to how they will elevate Edinburgh or Glasgow to the status of other major international cities?
A currency union between an Independent Scotland and the UK could be a bad idea for both parties. The UK wouldn't want an independent Scotland to mismanage its economy to the detriment of the English, Welsh and N. Irish. The three main UK political parties have said they would not allow an independent Scotland to use the pound. Mark Carney, The Governor of the Bank of England, has said that "a durable currency union requires some ceding of national sovereignty" which would negate the notion of Scottish independence if it used the pound. Also, the reasons that Scotland doesn't want to join the Euro should also apply to a currency union with the UK. The recent catastrophic economic collapse of Greece trying to operate within a currency zone shared with Germany is a sobering and relevant example as to why an independent Scotland should not share the Pound. Do the Scottish Nationalists have detailed contingency plan as to how an independent Scotland could operate without the pound?
Scotland's two biggest banks, Royal Bank of Scotland (RBS) and Lloyds have bank assets twelve times the size of its GDP. The equivalent multiple for the rest of Britain is below five; for Ireland on the eve of the financial crisis it was about seven. In another economic meltdown Scotland would struggle to rescue its banks. Do the Scottish Nationalists have detailed plan as to how they will manage their new banking system to avoid the recent problems of other small countries such as Iceland, Cyprus and Ireland?
Scotland would find it difficult to get all 27 of the other member countries to agree admit them into the European Union. Spain for one would not want to admit Scotland, as it would set a precedent for Catalan independence. Spain has already blocked Kosovo's membership bid because it broke away from Serbia. There are other separatist movements within Europe which could cause some other countries to veto Scottish membership. Do the Scottish Nationalists have a plan B for the possibility of independence outside the European Union?
Scotland is seeking independence at the time their North Sea oil reserves are running out and at a time when large shale oil reserves are being discovered in England. Do the Scottish Nationalists have a detailed plan as to how they will manage their future economy without North Sea oil?
→ The 2008 Financial Crisis was Primarily a Failure of Socialism.
While these are important questions that need to be answered before the big day, finding these answers are harder than it may seem as getting straight answers from Salmond and Co. is proving to be a reporters nightmare.
As of the past month or so whole debate is nothing but meaningless bluffs, false claims (from both sides) and a growing rejection of the idea that Scotland can survive as an independent country.
The true answers to these questions are likely to never be 'set in stone' as each party cannot afford to give away any weaknesses, especially Salmond and Co. and for that reason, the Scottish Nationalists continue to shy away from the true answers to these questions, which seems to have them on the run with the No campaign hot on their heels.