Melasma, also popularly called chloasma or pregnancy mask, is a hyperpigmentation of the skin making the skin's color unbalanced. When melasma happens when a woman is pregnant, it is called chloasma. It shows as a dark-colored blotch, usually brown with irregular borders. It is typically found on the facial area particularly the cheeks, chin, forehead, nose and lips. But it is a relatively good thing for it is not malignant, not tender, not itchy and not accompanied with other symptoms but the unsightly patch itself. Gender-wise, women are more involved most especially those that are carrying a child or are taking medication either for birth control or supplying hormones after menopause.
Melasma manifests slowly. Several studies report that they still cannot give the stringent cause of melasma but can only give its most feasible causes based on the cases. The most well-known is the overproduction of melanin when there is overexposure to the sun. The same reason, melanin overproduction, but this time, a different cause – the hormones estrogen and progesterone – is another feasible explanation for melasma growth. Another influential cause is the history of acquiring melasma in the family. Another cause is having a disorder involving the thyroid glands which leads to an excess production of the hormone that stimulates the melanocytes – the cells that produce melanin.
In today's time, anyone can choose from various treatment modalities to accelerate the "removal" of melasma. Utilizing topical creams consisting of hydroquinone, tretinoin, or azelaic acid are the main treatments. Hydroquinone's effectiveness rests on its capacity to stop tyrosinase functioning which then stops the generation of melanin. The available strengths of hydroquinone in topical creams are two percent, four percent and higher than four percent. With rising concentrations, success rises together with the chances of adverse effects. Tretinoin's mechanism, on the other hand, is through the increased manufacture of collagen and the removal of keratin on the skin's epidermis – the topmost layer. But tretinoin cannot beat the strength of hydroquinone. As a result, tretinoin comes in combination with hydroquinone. Azelaic acid's mode of action is the decrease in the normal functioning of the melanocytes and this is proven to be more effective than the two percent concentration of hydroquinone. But all these three have minor negative effects such as skin irritation, itching and redness. Chemical peels are now attainable to help remove the appearance of melasma by mildly exfoliating the skin. The doctor evaluates if he or she would use a light, medium or deep type of chemical peel. Having the same mode of action as chemical peels, dermabrasion exfoliates the skin but with the use of a vacuum and a scraper – a manual process. Another treatment mode is laser therapy but which does not generate successful outcomes and at the same time, increases your risks for acquiring possible complications. However, most of these treatments, especially the use of chemicals or laser, can possibly lead to complications such as scars, tissue death and further skin pigmentation if not properly used. Moreover, they are much more expensive. Therefore, doctors still recommend topical creams containing hydroquinone despite few reported side effects.
But whichever of the aforementioned treatment options you choose, keep in mind that effects are achieved slowly for melasma's development is also a slow process. Lastly, to not waste the work being done by the treatment, stringent avoidance of the sun is recommended.


Land for sale in Worcester County, Massachusetts, recently totaled about $263 million and almost 4,300 acres. It is the county with the most land currently listed for sale in Massachusetts. Worcester County is the largest county in Massachusetts (1,511 square miles). Worcester County is in the Central region. Farms in the area are principally focused on livestock production (classified by the USDA to include cattle, poultry and hog farming). To find more Massachusetts land and rural properties , sign up for Land And Farm's Massachusetts land-for-sale email alerts and never miss out on a new listing again! You can also search Land And Farm to find real estate agents in Massachusetts who specialize in selling land, rural acreage and other recreational property in regions throughout Massachusetts, including farms and ranches for sale in Worcester County.


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Argon 18's Focus on Performance
Argon 18 bikes are known for their ride quality, contemporary design, and high performance – for top pros, local circuit champions, and everyday riders alike. We use a rigorous process of design, engineering, testing, refining, and validating, and apply leading technologies and tools to prioritise premium performance and rider safety. Go behind the scenes at Argon 18 to learn more about what sets our bikes apart.
Carbon Engineering
Like most high-performance bikes, Argon 18 bikes are made from carbon fibre composite. Both performance and safety characteristics of our bikes are determined by the structural characteristics of carbon fibre, and by the precise benchmarking, testing and simulation modeling as part of the structural engineering process. Joffrey Renaud, Lead Composites Engineer, and Pierre Legay, Structural and CFD Analyst, take us behind the scenes to understand a core part of our process.
What are the characteristics of carbon fibre composite?
All "carbon" bikes are actually made of a composite: a mix of carbon fibres in a matrix of epoxy resin. Carbon fibres are bundled into thin layers, or plies, within this epoxy matrix. Carbon fibers are used for their high stiffness and strength along the fiber direction, and for their low density.
How does layup affect our lineup?
Our lineup features three levels of performance in most categories: Pro, Elite and Cyclosportif. Each of these levels has requirements when it comes to the choice of carbon layup, and each bike category also has unique characteristics. An Elite level gravel bike demands a different layup than an Elite triathlon or road race bike, for example. Even though we have three levels of carbon layups that match our levels of performance, the way we use them will differ from one frame to another in each of our model segments.
Our work at the CDCQ
Argon 18 is collaborating with the Composites Development Centre of Quebec (CDCQ) to refine our fabrication processes and expand our hands-on knowledge of carbon engineering and manufacturing. This project involves the production of prototype frames, with our R&D team involved in the process from start to finish: creating the layup, designing all the tools required for fabrication, such as mandrels and layup jigs, laying the plies, testing and validating the resulting frames.
What do we mean by layup optimization?
An optimized design solution provides the best possible result when a constraint is placed on a set of variables. For example, the variables in frame design include the number and orientation of plies in a layup, the materials, and the tube shapes. The constraints come from the specific benchmarks that we want to achieve with the bike, such as specific stiffness targets and strength.
Aero is often seen as the holy grail of cycling: aerodynamic performance influences everything from clothing to components to positioning, and of course the design of the bike itself. What are the main principles of aerodynamics, and how do we address them in our bike design?
Aero Drag: the Basics
There are four major contributors to rider displacement: air resistance, altitude gain resistance, acceleration resistance and mechanical loss. The ratio of the contribution of these four forces changes based on riding conditions. Altitude gain resistance increases as the grade of a climb increases, for example, and air resistance decreases on that same climb as the rider slows down.
CFD is a numerical simulation tool to predict aerodynamic performance. You've probably heard of CFD being referred to as a "virtual wind tunnel", but both CFD and the wind tunnel have their own unique role in the development process. In CFD, we can see how the flow of air - the "fluid" in CFD - behaves around rider and bike frame. This analysis can lead to design changes that improve the flow around fork and frame shapes.
Testing in the Wind Tunnel
There are two parameters we can address to improve the aerodynamic performance of an object: its shape and its frontal area. We can see the effects of adjustments to both of these parameters by measuring the CdA, or drag coefficient. In the wind tunnel, a controlled air flow with known velocity is applied to the rider. Load sensors are used to measure the force applied by the air on the rider, and yaw angles are carefully weighted to reflect real-world conditions.
How does aero testing affect our design process?
Aero performance is one of the key features of our bikes, and is repeatedly measured and evaluated throughout the development process. However, aero is always analysed in conjunction with how new shapes affect stiffness and weight targets. All parameters are evaluated simultaneously, in a holistic approach. We evaluate initial design concepts this way so that we can be efficient in producing design iterations that move us closer to our performance goals across all parameters.
Prototyping is a key stage of our development process where we produce a physical model to validate or further investigate our design intentions. We use prototyping as part of two key processes: our bike development, and our advanced research projects.
There are several major reasons why we produce prototypes as part of bike development:
To test real-world functionality: we test the performance of design features such as integrated cables or component compatibility, or to be sure the bike's assembly will be mechanic-friendly.
To continue performance testing, such as the wind tunnel testing described in our article on aerodynamics, which is often undertaken with a prototype.
To undertake safety testing.
Prototyping as Part of Design Validation
Early looking samples allows us to check the quality of the mould. We will be able to see if the surfaces of the frame are smooth, the tube shapes are accurate, and if the fit with required plastic parts is compatible. We are also able to test artwork at this point, to be sure the final product will be produced true to the design intentions.
Prototyping as Part of Advanced Research
We often use prototyping as part of our ongoing advanced research programs. In this research we may not be working on one specific model, but rather looking to gain new knowledge on the behaviour of certain areas of the bike frame, or further develop our expertise in composite engineering.
The Link to Manufacturing
The expertise we develop with our prototyping techniques means we are able to propose new methods to our partners in our manufacturing facilities based on our own hands-on experience with the techniques of production. This makes our working relationships more efficient, and adds a level of collaboration that helps us provide the best possible products to our riders.
The safety and performance quality of our bikes is our largest priority. Our testing and quality control protocols are among the most rigorous in the industry, and we are constantly adding to or augmenting our test standards to ensure the best possible experience for our riders.
Overall, our testing falls into two main categories: performance requirements and safety requirements. Safety requirements are industry-wide standards. Performance requirements include assessing the benchmarks we set for each bike, such as weight, comfort, handling, stiffness, and aerodynamics, among other performance benchmarks.
Safety requirements are industry-wide standards. Often these are set by ISO guidelines (International Organization for Standardization), although we have developed and implemented additional tests where we feel appropriate.
Testing Protocols
Safety tests take several forms to be sure we test all possible parameters and meet all international safety standards. In static tests, a load is applied to the frame and maintained during a short time. In fatigue tests, a load is applied under repetitive movement. In impact tests, a weighted striker is dropped on the frame, or the frame is dropped with weights on it.
Performance requirements
Performance requirements include assessing the benchmarks we set for each bike, such as weight, comfort, handling, stiffness, and aerodynamics, among other performance benchmarks. Unlike safety tests, these tests produce discretionary results, based on targets that we have set for ourselves.
The final step in our design process is manufacturing, when we enter the production phase and are able to deliver our products to our network of shops and riders around the world. Like most composite bike manufacturers, our bikes are largely manufactured in Asia. However, our team is closely involved in the manufacturing process. Our knowledge of manufacturing has been highly refined with our work with the CDCQ, which allows us to understand how production processes affect and enhance quality and performance characteristics. When we work with factories, we can provide precise information about the layup and desired ride characteristics of the bike, and know that we are working collaboratively with the production team.
Preparing the Mould
Production processes begin with cutting pre-preg, a carbon fiber fabric that has been pre-impregnated with resin, in plies according to the layup of the particular bike. The plies are placed on a mandrel that is composed of a solid part inserted in an inflatable bladder. The mandrel is then placed in the mould. Unique moulds are made for each bike design, as well as size – each size within a model run has its own mould.
Partnerships for Quality Production
Our end-to-end involvement in manufacturing affects more than just our relationship with factories. The constraints of manufacturing influence design. Starting at square one, we design our bikes with manufacturing processes in mind, so that our designs are achievable, and so that the performance attributes we engineer into our bikes are realised in the final product.
Our Holistic Approach
Argon 18's unique products come from our unique approach to the design and production process. Design, simulation, prototyping, testing and manufacturing all work as a cycle to continually deliver the best possible performance for our riders, because we know that you're constantly pushing yourself to perform better… and so are we.
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redpajama_set_name: RedPajamaCommonCrawl


Jorge Sampaoli is the World's Best 2015 !
Copa América champion coach of Chile, Jorge Sampaoli, has added to his trophy cabinet with a convincing win as the IFFHS World's National Coach 2015.
Despite tough opposition from experienced European coaches, football experts from more than 50 countries world-wide had little hesitation in awarding Sampaoli a massive 136 points well ahead of German runner-up Joachim Löw on 57 and England's Roy Hogdson taking third place on 46 points.
The Argentin Jorge Sampaoli, 55 years old, has been coach of the Chile National Team since 2012. He coached for the first time a club, Juan Aurich,in 2002 in Peru, then was in Equator, in Chile where he won the championship with Universidad Chile (2011/2012) leading to his appointment an national coach. He performed well at the World Cup 2014 and won ,for the first time since 99 years ,the Copa América for Chile.
Löw was the outstanding coach last year and won the award in world-wide voting while Hogdson claimed third place for his efficient year with the England team.
Swiss coach, Marcel Koller realized a great jump to rang 4 with the excellent performances of Austria. Michael O'Neill (North Ireland) , Giovanni De Biasi (Albania), Lars Lagerbäck (Iceland) and Chris Coleman entered in the World's Top 10.
Right now I suppose it is Lagerback!


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Q: Datatable Highcharts can anyone help me, im trying to display the chart in diferent columns but its only showing me the data in one.
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db data:
date

fecha	No Conformidades Registradas	No Conformidades Cerradas	1 dia	2 dias	3 dias	4 dias	5 dias	6 dias	7 dias	8 dias	9 dias	10 dias	11 dias	12 dias	13 dias	14 dias	15 dias	+15 dias

JUL, 2014	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

MAY, 2014	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

APR, 2014	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

FEB, 2014	5	2	1	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0

JAN, 2014	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

SEP, 2013	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

AUG, 2013	3	3	0	0	0	1	0	0	0	1	0	0	0	0	0	0	0	1

JUL, 2013	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0

JUN, 2013	1	1	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0

OCT, 2013	4	4	0	0	0	1	1	0	0	1	0	0	0	0	0	0	0	1

fecha	No Conformidades Registradas	No Conformidades Cerradas	1 dia	2 dias	3 dias	4 dias	5 dias	6 dias	7 dias	8 dias	9 dias	10 dias	11 dias	12 dias	13 dias	14 dias	15 dias	+15 dias

A: Well your example seems to work fine, see the demo: http://jsfiddle.net/v7gMP/
 var options = {
    xAxis:{
        categories:[]
    }
};

redpajama_set_name: RedPajamaStackExchange


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Home / All hotel reviews / Park House hotel and spa: a West Sussex secret (but not for much longer)
Park House hotel and spa: a West Sussex secret (but not for much longer)
It's been receiving guests for more than 60 years but Park House hotel and spa is only now making the transition from well-kept local secret to firm fixture on the British country house hotel scene. With a new general manager – Mark Yates, formerly of Harbour Hotels and Careys Manor – and its spa PH2O being shortlisted for the 'Best Boutique Spa' category in the prestigious Good Spa Guide awards, Park House hotel is making a name for itself and, judging by my recent stay there, seems more than up to the task.
Park House hotel has two good-sized swimming pools; one outside and the other in the main spa building which also contains a gym and treatment rooms
Hidden deep in the West Sussex countryside – if you drive up from nearby Goodwood then the journey takes in single-track roads with high hedges and invariably a tractor coming the other way, the easier route is down from Midhurst – Park Hotel hotel isn't vast but manages to pack a lot into the space it has.
At the back of the hotel is a golf course, a bowling lawn, two tennis courts and a croquet lawn
The grounds behind the hotel are surrounded by lush green Sussex countryside and offers two lawn tennis courts, a bowling green, a small but perfectly-formed six-hole golf course, two helipads, and a croquet lawn. The spa has both an indoor and an outdoor pool – the weather was warm enough at the beginning of October for me to swim in the outdoor pool – as well as a jacuzzi, a steam room and sauna and a gym and fitness studio.
The spa (pictured, the indoor pool and hot tub) at Park House hotel was shortlisted for a prestigious Good Spa Guide
However this doesn't mean that you have to work yourself into the ground at Park House hotel. Instead of hitting the gym I opted for an extremely relaxing massage following my swim, had a foot spa which was thoughtfully provided in the changing rooms, before floating back to my room in my fluffy white toweling robe.
There are 12 en-suite bedrooms in the main house, six in the separate South Downs Cottage, two in Polo Cottage and one in Bay Tree Cottage; the cottages can all be hired out for exclusive use, such as for families, wedding parties or country sports enthusiasts.
Our room in South Downs Cottage was immaculate and decorated in a smart, classic style
The bathroom wasn't spacious but was very smart, with underfloor heating, a walk-in shower (on the right) and a range of toiletries
Our room has a cosy sofa and a balcony overlooking the garden below
We stayed in South Downs Cottage and our first floor room was immaculate, with a balcony overlooking the kitchen garden and a very smart bathroom with underfloor heating. Again Park House hotel managed to pack a lot into a compact space, with all the essentials of a good hotel room: coffee machine, desk, TV, plug points everywhere and ample storage space.
Park House hotel was originally run by owners Ione and Michael O'Brien as a home where friends could stay, and gradually evolved into the country house hotel it is today, run by their grandson Seamus. This gives it a warm and cosy feeling, such as in the lounge where people were having afternoon tea, or meeting for pre-dinner drinks, but means some areas feel a little old-fashioned, such as the conservatory where dozens of photos of celebrities from yesteryear adorn the walls. I'd say Park House hotel fits into the traditional hotel category rather than being a modern boutique hotel but that's its charm; that and the very friendly and efficient staff.
The lounge where guests enjoy afternoon tea or pre-dinner drinks
Dinner looked promising from the very start, with clear and well-thought out menu of classic British dishes. We had the cod with wilted spinach and handpicked crab with avocado cream to start, and then both chose the lamb rump, having it with green beans, olives and saffron potatoes which were supposed to accompany the sea trout dish instead: however the kitchen was happy to accommodate.
Handpicked crab with apple and avocado cream starter
A impressively-sized lamb rump with quails eggs and new potatoes
The lamb was perfectly cooked and was the largest helping I'd seen for some time: we just about had room to share the pistachio, chocolate and raspberry souffle before ambling across the gravel driveway to our cottage and bed.
Pistachio souffle with chocolate sauce and raspberry sorbet
Breakfast was just as efficiently cooked and served as dinner, with a good selection of cooked dishes to enjoy from our table overlooking the gardens. When we left, having enjoyed a lengthy walk around the grounds in the early morning sunshine, Park House hotel was a hive of activity, from people arriving for fitness classes to meetings being held in the lounge over morning coffee. Park House might be hidden deep in the heart of the Sussex countryside but its new sense of energy and purpose is already making waves.
Hotel information and to book Park House hotel and spa
Park House hotel and spa
Bepton, Nr. Midhurst
West Sussex GU29 0JB
Check availability and book Park House hotel by clicking here
Compare latest prices and read more reviews of Park House on Tripadvisor by clicking here
If you like boutique country house hotels then you won't want to miss:
Dormy House hotel in the Cotswolds – so snug, you'll never want to leave
Barnsley House hotel and spa – a wonderfully cosy Cotswolds hideaway
Relaxing in grand style in Cotswolds hotel the Hare and Hounds Tetbury
Luxury after lockdown: a Covid secure stay at Fawsley Hall Northamptonshire
UK hotels after lockdown: is it safe to stay in a hotel right now?
Whatley Manor review: a Cotswolds gem revisited (with added oxygen)
An unscheduled stay at former 18th century sugar house, Hotel du Vin Bristol


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