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Transcript Delivers Blow
PUBLISHED: 1:00 PM 27 Nov 2019
UPDATED: 6:46 PM 27 Nov 2019
Transcript Delivers Blow To Dems, Reason For Withholding Aid Destroys Impeachment
Mark Sandy's deposition clearly shows there was no quid pro quo, there was no bribery, and there certainly wasn't anything unscrupulous about this decision.
Adam Schiff keeps looking more and more stupid, partisan, and guilty himself. (Source: CSPAN screenshot)
Although by now, most Americans understand that the impeachment proceeding is a sham, designed to attack and remove the president, another blow was delivered yesterday after the transcript of Mark Sandy's deposition was released.
The information it contains delivers yet another blow to the impeachment frame up orchestrated by congressional democrats. In fact, it outlines very clearly why aid to Ukraine was withheld… and it had nothing to do (like Joe Biden's extortion) with getting something.
Townhall reported:
House Intelligence, Oversight and Foreign Affairs Committees released White House Office of Management and Budget (OMB) official Mark Sandy's deposition transcript on Tuesday. The transcripts reveal aid to Ukraine was put on hold because President Donald Trump was concerned about other countries' failure to provide aid.
Q: Okay. When did you go on leave?
A: I was out of the office starting on Monday, July 8th.
Q: So you did not hear anything about Ukraine security assistance possibly being on hold at any time during the month of June or during that first week of JuIy?
Q: Did you hear of any questions that were being raised by OMB about Ukraine security assistance at the end of June or the beginning of July?
Q: Can you describe what you heard?
A: I heard that the President had seen a media report and he had questions about the assistance.
Q: When did you hear that the President had seen a media report and had questions about the assistance?
A: 0n June 19th.
Q: Do you know what media report that was?
A: I don't recall the specific article.
Q: Who told you that the President had these concerns on these questions?
A: Mike Duffey.
Q: And that was the conversation that you had with Mr. Duffey on June 19th?
A: I believe it was an email.
Q: Okay. Can you describe what that email said?
A: The email expressed an interest in getting more information from the Department of Defense.
Q: And what kind of additional information?
A: A description of the program.
Q: What exactly did Mr. Duffey say, to the best of your recollection, in that email?
A: That the President had questions about the press report and that he was seeking additional information.
Q: Anything else in that email?
A: Not that I recall.
Q: Between JuIy 19th and JuIy 22nd, including July 22nd, did Mr. Duffey provide you any explanation as to why the President wanted to place a hold on Ukraine security assistance?
Q: Did you ask?
Q: And what was the response?
A: He was not aware of the reason.
Q: To the best of your recollection, what precisely dld he say to you when you asked for the reason for the President's decision to place a hold on security assistance?
A: That he was not aware.
Q: He simply said, "I don't know"?
Q: Did he indicate that he was going to try to get more information as to why the President was placing a hold on security assistance?
A: I am pausing because I — there was certainly a desire to learn more about the rationale.
Q: Whose rational?
A: A desire on the pant of Mike Duffey, myself, and other people working on this issue. So I want to answer your question accurately in terms of saying, that desire was acknowledged.
Q: All night. Did Mr. Duffey say that he was going to try to get additional information as to the reason for the hold?
A: Yes. He certainly said that if he got additional information he would share it with us.
Q: Okay. At any point in time, from the moment that you walked into the SCIF to anytime in history, has Mr. Duffey even provided to you a reason why the President wanted to place a hold on security assistance?
A: I recall in early September an email that attributed the hold to the President's concern about other countries not contributing more to Ukraine.
In a joint statement, the Chairman of the House Intelligence, Oversight and Foreign Affairs Committees attempted to spin the testimony.
"The testimonies from Ambassador Reeker and Mr. Sandy continue to paint a portrait of hand-picked political appointees corrupting the official levers of U.S. government power, including by withholding taxpayer funded military assistance to Ukraine, to further the President's own personal political agenda.
"Mr. Sandy confirmed that he was told by the office of Mick Mulvaney, the Acting White House Chief of Staff, that the President himself had directed the hold on security assistance to Ukraine. However, he was provided no other reason or justification for the hold when he was directed to implement it. And in fact, after he raised concerns with OMB leadership and lawyers that the withholding of funding for Ukraine may violate the law, his authority for approving security assistance funding was revoked and given instead to a hand-picked Trump OMB political appointee.
"Finally, we learned from Mr. Sandy that he was first informed in early September—approximately two months after the hold was implemented—that the reason for the hold was due to concerns regarding European countries not paying their fair share of foreign assistance. Given other testimony and the public admission by Mr. Mulvaney that the aid was held to pressure Ukraine to conduct the investigations desired by the President, this constitutes powerful evidence that this justification was concocted as an after-the-fact rationalization to justify the hold."
Rep. Lee Zeldin (R-NY) took to Twitter to slam House Intelligence Committee Chairman Adam Schiff for pushing the quid pro quo theory.
The transcript for OMB's Mark Sandy was just released. The ONLY reason he was ever given why there was a hold on $ to Ukraine was "the President's concern about other countries not contributing more to Ukraine." NOT bribery. NOT quid pro quo or any other WACKY Schiff conspiracy!
— Lee Zeldin (@RepLeeZeldin) November 26, 2019


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Avro 519 byl britský prototyp bombardéru, vzniklý v roce 1916 vývojem z plovákového letounu Avro 510.

Vznik a vývoj
Jednalo se o konvenční dvouplošník s dvoukomorovým systémem mezikřídelních vzpěr a výrazně větším rozpětím horního křídla. Plováky byly nahrazeny kolovým podvozkem ostruhového typu s ližinou mezi nohami hlavního podvozku, křídla byla řešena jako sklopná a letoun byl opatřen svislou ocasní plochou stejného typu jakou užívalo Avro 504B. Počátkem roku 1916 byly Royal Naval Air Service objednány dva jednomístné prototypy, poháněné kapalinou chlazeným motorem Sunbeam Nubian o výkonu 150 hp (112 kW). Tato zakázka byla brzy následována objednávkou Royal Flying Corps na dva dvoumístné prototypy poháněné motorem Sunbeam o výkonu 225 hp (168 kW).

První z exemplářů dvoumístné varianty nesl označení Avro 519A, zatímco druhý, který se ještě podstatněji odlišoval novými nosnými plochami se zvětšeným rozpětím horního i dolního křídla, u obou stejným, ve snaze zlepšit stoupavost typu, obdržel typové označení výrobce Avro 522.

Stroje byly užívány pouze ke zkouškám, a nikdy nebyly operačně nasazeny. Poslední z nich se na letišti ve Farnborough vyskytoval ještě v dubnu 1917.

Podle některých pramenů se v dvacátých letech ve výzbroji 2. peruti Royal Canadian Air Force vyskytl jeden exemplář označený  Avro 522A.

Specifikace (Avro 519)
Údaje dle publikace Avro Aircraft since 1908

Technické údaje
 Osádka: 1
 Délka: 9,98 m (32 stop a 9 palců)
 Rozpětí:  19,21 m (63 stop)
 Výška: 3,56 m (11 stop a 8 palců)
 Nosná plocha: 55,8 m² (600 čtverečních stop)
 Hrubá hmotnost: 1 360 kg (3 000 lb)
 Pohonná jednotka: 1 × řadový osmiválec Sunbeam Nubian
 Výkon pohonné jednotky:  111,8 kW (150 hp)

Výkony
 Maximální rychlost: 121 km/h (75 mph)
 Dostup:
 Stoupavost: 1 m/s (200 stop za minutu)

Výzbroj
 pumy na podtrupových závěsnících

Odkazy

Reference

Literatura

Související články
 Avro 510

Externí odkazy
  Avro 519  na britishaircraft.co.uk

Britské bombardéry
519
Letecké prototypy
Dvouplošníky

redpajama_set_name: RedPajamaWikipedia


The Book Review: Made for Us by Samanta Chase- Feature + Review+ Giveaway! Meet The Shaughnessy Brothers!!
Made for Us by Samanta Chase- Feature + Review+ Giveaway! Meet The Shaughnessy Brothers!!
Made for Us by Samantha Chase is a 2015 Sourcebooks Casablana publication. I was provided a copy of this book by the publisher and Netgalley in exchange for an honest review.
This is the first book in a new series which focuses around the Shaughnessy Brothers. First up , is Aiden, the "go to" guy in the large family of overachievers.
In the years since the death of his mother, Aiden, who took her passing particularly hard, has been the rock of the family. He's built a successful career for himself, helps his father and all his highly successful siblings, but has little time left over to work on his own life. Over the years he has become controlling, staid, an unbending perfectionist, and has garnered a reputation for being difficult to work with.
Enter, Zoe, an interior designer, a transplant from Arizona, grieving the loss of her mother, looking to make a fresh start in North Carolina. When she is told to drop everything and her current client list in order to correct some huge mistakes for Aiden Shaughnessy, she gets a first hand, face to face , introduction to the famous 'dictator'.
I'm not sure where to start here to be honest. Aiden is a very unique character, not unlike a lot of workaholic, highly successful men, who are used to being in charge, barking orders and having them instantly obeyed. But, truthfully, Aiden isn't really the total jerk he appears to be at first glance. He has some difficult inner demons to exorcise. It occurred to me while I was reading this book that Aiden seems to have some kind of personality disorder. It bothered me to the point that I decided to do an internet search and lo and behold I discovered Aiden's symptoms matched, almost to the letter, the co-dependent personality.
He was afraid to let himself be who was, he expected himself to be perfect, he appeared rigid and controlled, he was afraid to let other people be themselves and let things happen naturally, he thought he knew best how things should turn out or how people should behave.
So, while Aiden is not the most likable person in the world, it's obvious he needs specialized help and frankly poor Zoe was not equipped to handle him. Zoe herself is dealing with a lot and Aiden's dark and brooding mood swings are mystifying to her, although Aiden's family is used to it, which is a huge part of the problem. As close as the family appears to outsiders, and as much as they would like to believe they are close knit, they are actually dysfunctional. The youngest child, seventeen year old Darcy, is just as much a victim to Aiden's heavy handed control freak tendencies as Zoe is. Then there is the patriarch of the family who enables Aiden and allows him to rule the family, because it's just easier that way. The other brothers have also found Aiden's leadership to be a relief since it has left them unencumbered with the burden of helping with their father and younger sister, freeing them to pursue their own paths in life.
I do think that if a serious issue is brought into focus in a novel, it might be a good idea to put a name with the face, so that readers will not presume this behavior is typical or normal. I love romance novels and their ability to bring difficult and misunderstood issues into focus, and of course I am a huge believer in the power of love and it's ability to bridge any gap, to heal any wound, to bring forgiveness, hope, and faith to even the most hopeless of situations. But, sometimes love must rely on common sense and that means seeking help from outside sources if need be.
After having said all that, I don't want you to think I disliked the story, because I DID like it! It's an unconventional love story and I love seeing very difficult and trying personalities come to their senses before it's too late. It was good to see Zoe finally get a grand gesture and have a little good come her way for a change.
The best part is that Aiden is not the only one who gets a wake up call, as his entire family will play a role in helping him understand he needs to face the inevitable changes that come in life and will help him see where he needs to make improvements. They all owe Aiden for one thing or another so, it was fun to see them come together to help him for a change.
Another charming aspect of the story was the mild paranormal undercurrent that cropped up from time to time that added a pinch of sentimentality and is a touching way to guide Aiden into understanding it's okay to be with Zoe and their relationship is meant to be.
There is a wonderful and very romantic ending and a happy ever after ,which is why we read these books and it makes it worth all the drama and tears and frustrations. This is a solid start to the series and I'm curious to see whose turn it will be next.


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Conservative Firebrand Candace Owens on Biden's Decline, Derek Chauvin Trial, and Meghan and Harry's Cries for Publicity
Live from Music Row Friday morning on The Tennessee Star Report with Michael Patrick Leahy – broadcast on Nashville's Talk Radio 98.3 and 1510 WLAC weekdays from 5:00 a.m. to 8:00 a.m. – host Leahy welcomed the host of the new evening talk show "Candace," Candace Owens to the newsmakers line to talk about her tweets on the elder abuse of Joe Biden, the trial of Derek Chauvin, and Meghan Markle's cries for attention.
Leahy: On our newsmaker line Candace Owens. Candace, on Wednesday you tweeted, the president of the United States is in severe cognitive decline and the entire world knows it. He gave an orchestrated kind of bizarre speech last night. What was your reaction to that speech?
Owens: I didn't watch even a second of it because I'm not into elder abuse.
Leahy: That's a good line. Your show is really going to be funny Candace. That's a funny line. (Laughs)
Owens: I do not. We have a senile person that's been installed in the Oval Office who was not given a press conference and over 50 days. Everybody in the entire world knows that Joe Biden is in cognitive decline. Everyone has known this since the second he announced that he was running for president of the United States. And the left stream media has done everything they can to protect him and to hide him and it's foolish.
It makes America look weak. and I will not be adding myself to the group of people who are going to pretend that this man is leading our country. He's not. He is a puppet. His strings are being pulled. I'm interested to see how long they are going to go without making him answer any questions from the press.
Leahy: What're your guess of if he will ever hold a real press conference?
Owens: I think the answer is no, you know, I think they used covid-19 as an excuse when he was running obviously when he was nobody was showing up to hear him speak and he just had a couple of cars honking at him in hidden locations. And they don't have an excuse now. So I think that they just keep you know doing what they're doing and pretending that it's completely normal that he's not speaking in front of the press or taking any questions.
It's a terrifying state to be. It's like is this even a real country? There was not a single person and not even the people that are pretending that they don't realize it that go to bed and think this is a man that is a strong leader of this country. It's actually quite sad and it's quite serious and it's bizarre would be probably the correct adjectives.
Leahy: Yeah. I think you're absolutely right about that. Other news of note. You're just so non-controversial Candace. (Owens chuckles) You had another tweet yesterday about the trial of police officer Derek Chauvin in Minneapolis. Will he get a fair trial?
Owens: If he doesn't get a fair trial then I think the implications are scary for the future. And I want to be clear here because people misunderstand I don't think there's a single person in America who thinks that Derek Chauvin is guiltless. Like we all think that Derek Chauvin did not act the correct way that day irrespective of the situation.
There's just no reason when somebody stops moving to remain on their neck for that long. But what we're talking about specifically are the charges that have been trumped up against to appease the public. This is not a third-degree murder charge. It should never have happened a third-degree murder charge. They can't prove it was their degree of murder.
The autopsy shows the longer form of people who have not snippy should go out and look for it to be longer form tape of exactly what happened that day. You know, George Floyd was saying he couldn't breathe long before he got onto the ground. It was clear to me having watched it that he was having a drug overdose. And that it's highly likely given the results that came back in his autopsy report that he put drugs in his mouth to get rid of it when the cops were approaching the vehicle. And he had an overdose.
So Derek Chauvin did not cause George Floyd's death. Unfortunately, the public is being deceived largely by the emotionality surrounding this case. And if he doesn't get charged with third-degree murder, which is likely he won't, based on evidence and we're going to see riots as we've never seen before because people don't understand that he should have never been charged for third-degree murder. So it's unfortunate. And it's almost like a catch-22. I don't see how it's good either way.
Leahy: Last question for you. A former Nashville resident Oprah Winfrey had a special interview with Prince Harry and Meghan Markle where they made a lot of allegations. My first question, will you invite Meghan Markle to be a guest on your new show, Candace?
Owens: As much as I think she'd love that because she's obsessed with getting attention and pretending that she wants privacy, she will not be receiving an invite to my show because I am not looking to highlight a couple that has the audacity to accuse an entire country or to try to import America's obsession with race overseas to England.
It's is just so patently wrong and has upset my family of course on a lot of levels because my husband is English. And I spent a lot of time in England and it's just so not indicative of who they are. And it's just such scapegoating. Such spinelessness. And to Oprah, I don't think we should be calling this an interview. We should be calling this a PR stunt. She didn't ask any hard-hitting questions. She didn't ask them for any proof. She is friends with Meghan Markle.
So pretending this was a no-holds-barred interview is just foolish. Meghan and Harry had the questions long before they were ever asked about them. And they crafted this interview to help them launch their careers in America and a race-obsessed America because the United Kingdom wanted one nothing could do with the narcissist Hollywood-driven couple. But let me tell you how I really feel. (Laughs)
Leahy: I was so glad to see your comments about that because I've studied the difference between a constitutional monarchy and a constitutional republic. I have to say Queen Elizabeth II who's been the queen since 1952 has been a tremendous Monarch in England, in the United Kingdom, and it seems to me that Prince Harry has got some unresolved issues.
Owens: Right.
Leahy: And Meghan Markle making these allegations substantiated allegations is just looking for publicity.
Owens: That's exactly right. And I think the worst part of the entire interview is when she says there were questions surrounding his skin color. She made that seemed like that was something harmful. It is completely harmless. I have a biracial child. If I told you how many times while I was pregnant we were saying, I wonder what color is skin color will be? I wonder how dark he'll be?
Do you think he'll be light? Do you think he'll be dark? such a natural question for excited parents and family members that are trying to envision what your child is going to look like when they're multicultural and multiracial. And she left it absent of context and just said there were questions surrounding his skin color.
I could just see right through her. Look Meghan Markle was a d-list actress. Nobody knew who she was. And today she remains a d-list actress that unfortunately, we all have to know who she is because she keeps inserting herself in this victim narrative that's a never-ending series of victimhood.
Leahy: Candace Owens, her new show "Candace" debuts next Friday.
Special Guest Candace Owens Talks About Becoming a Nashvillian and Her New Show 'Candace'
Live from Music Row Friday morning on The Tennessee Star Report with Michael Patrick Leahy – broadcast on Nashville's Talk Radio 98.3 and 1510 WLAC weekdays from 5:00 a.m. to 8:00 a.m. – host Leahy welcomed conservative political commentator and host of the new show 'Candace' to the newsmakers line to talk about becoming a Nashvillian and her new show "Candace."
Leahy: We are joined on our newsmaker line by that great conservative Candace Owens who's moved to Nashville and has a new talk show coming called "Candace." if you're driving into Nashville today, you can see the Billboards announcing the program. Welcome, Candace.
Owens: Hi!
Leahy: We are delighted that you've moved to Nashville. How do you like it here so far?
Owens: Oh, we are so thrilled. Actually, my husband had always wanted to move to Tennessee and this just ended up lining up. The stars lined up so we couldn't be happier to be here. And what a perfect place to start a family.
Leahy: It is a great place. And of course, we love and I'm sure you'll love the no state income tax. How about that?
Owens: That's the best thing especially coming from Washington D.C. So that is what we call a perk.
Leahy: It sure is. So tell us, Candace, you are now part of the folks at The Daily Wire. I was over there a couple of weeks ago and had lunch with Jeremy the CEO. Great guy, great group. You're launching a new talk show tell us about it called "Candace."
Owens: Yes. I'm so excited. I'm actually going to be the first girl to join the guys over at The Daily Wire. So I get to break that up a little bit. And it was really such a creative process. Jeremy and I came together and said what sort of missing from the media spectrum. There's a lot missing first and foremost. Obviously just allowing conservatives to be in culture has always been problematic.
But we also felt like we were losing sort of the late-night talk show greats. It kind of feels like it died with Jay Leno and now it's sort of everything is so politicized and so polarizing at the expense of the conservative. So we thought why not actually do a live studio audience show that has a late-night vibe and sort of brings something unique to the culture at the same time. And bam! Candace was born.
Leahy: What a great idea I cannot watch any of the other late-night shows. They're just unwatchable, unbearable. I turn it off within like two seconds of seeing it.
Owens: They're also just not funny anymore. It's like they're trying so hard to be offensive and to do everything at the expense of more than half of America. They just sort of lost their touch and they seem to be angry all the time. And that's not to say that my show is going to be all humor. Obviously, I think that I sort of sit somewhere in the middle.
I think humor is the best way to deliver it. Sometimes you just need to deliver the message. And we have so much going on and so many people that feel are unheard. and so to also deliver monologues that are meaningful and hopeful I think is also probably the most important adjective. Because a lot of people are feeling hopeless in today's circumstances. But there's plenty to be hopeful about.
Leahy: I like that hopeful angle. and you're very right. These other late-night talk shows are just not funny. They're just bad to watch. I think your program will be a big big hit. Now, you said something very important. You're going to be taping this before a live audience here in Nashville. Is that right?
Owens: That is correct. And that is something that I think is so exciting.
Leahy: Just you and me here talking now. How can I get tickets?
Owens: (Laughter) You know what? I don't know. I'm telling you there are so many things at The Daily Wire the other day. I was walking through the offices and a girl had on a Candace t-shirt, and I went where do I get one of those? The marketing department knows more than me about these things. But they will be announcing I think this week, you know, the first episode that we're shooting is obviously a smaller crowd.
And then I think that by the end of next week, they're going to launch a link live on the website where you can grab tickets. And now I guess we will be the required stop for every party coming in, every bachelor party, and every bachelorette party will say they've got to go for a live taping of Candace.
Leahy: Oh absolutely now, so this is going to come out once a week on Fridays, is that right when it comes out?
Owens: That is correct. And then we might scale up. We just have so many ideas right now that we're so excited about. We're already in our heads were 10 episodes out. We've already written so much content that we think inevitably we'll end up scaling up the show but we are going to start with just once a week.
Leahy: So the late-night shows have writers do you have a group of writers working with you? So actually I write my own monologues. I am a writer obviously a published author and majored in English and journalism. So I love to write. But it is a collaborative process. They brought in some other writers to kind of go back and forth on ideas.
And that is just such an exciting process. I mean to be in the room and be talking about the topics that I say to them hey, I want to make this entire episode regarding this specific topic. And then we sort of you know, fit in the room and throw around a ball and laugh and come up with funny jokes. Just at one another. So it is a collaborative process but it's being largely led by me.
Leahy: So Candace, here's what I think. I think this is going to be such a big hit that you won't be able to just do it once a week.
Owens: From your mouth to God's ears.
Leahy: Take a look at me right? So I'm 66 years old. I remember listening to Johnny Carson. I remember listening to Jay Leno. I can't listen to any of these other folks. I will watch your program and I will find it interesting and amusing. My guess is it'll be informative but hopeful and funny. That's what you need. That's what you need.
Owens: Right. We just need to not take ourselves so seriously. And at the same time, there are obviously incredibly important issues that are going on. I'm so hopeful that we're going to bring something really unique to listeners. And once again to just sort of say to the world that we're not ashamed to be conservative. I think there's this sort of this feeling that's definitely like being pushed upon us by the mainstream media that we're somehow not allowed to exist.
Leahy: Right.
Owens: And there's so many of us. So it's going to take a little bit of courage. And I want to always inspire that courage amongst my listeners and my followers to say, you know, I'm here, I'm Candace, I'm doing this unapologetically and you should too.
Leahy: So your Twitter account is @RealCandaceO. How can people get your program? Is it part of the daily wire subscription or is it going to be free for a while? How's that going to work?
Owens: Yes. And you definitely want to subscribe to the daily wires? You can go to DailyWire.com/subscribe. You can use my code, which is CANDACE of course. And you are correct that you can follow bits of the show. We have an Instagram handle and a Twitter handle so you can follow me as you mentioned at @RealCandaceO. But you can also follow @thecandaceshow. And of course, if you follow me on social media, I'll be pushing out so much content that it will be very hard for you to miss.
Leahy: So the first show is coming a week from today. It's going to be released a week from today?
Owens: That's correct.
Leahy: So what we'll do is just you and me talking here. We'll talk to Jeremy about this. Just send us a few clips of it like, you know before and we'll play them on the show so people on the radio show will have an idea of the fun that's coming.
Owens: So people have an idea of the fun. This coming absolutely will give you guys a little bit of an exclusive Tennessee deserves the exclusive everything's happening in this state. so we can definitely make that happen.
Leahy: Why is it do you think that so many conservative media outlets and people are moving to Nashville, Tennessee and in Middle, Tennessee?
Owens: Because they're being chased out. (Laughter) The policies of New York and LA are no longer desirable. It's not a place to raise a family. Look at the crime rates that are skyrocketing. What you're really seeing in these coastal cities is just a manifestation of these socialist policies. The socialist thuggery as I like to say that these Democrats come up with and people realize that you just can't live like that.
It doesn't work when you're incentivizing criminality. It doesn't work when you're punishing people as law-abiding citizens. It doesn't work when everything becomes an expense to the law-abiding taxpayer and everything becomes free to people that don't want to pay taxes. People that don't want to have borders and that don't want to have rules. And so the people are fleeing. I think I read the other day that the top two states that people are running to are Texas and Tennessee. And we were itching to get to one or the other and here we are. I'm a Nashville resident and that just feels amazing to say.
Leahy: You are a Nashville resident and we are so happy. And you have a baby. You just had a baby.
Owens: I do. Yes, it's crazy to think that. My son who is half English and half American is going to be raised in Tennessee. It's just an amazing feeling. We always talk about that just being raised around people with good morals and people that I love this country. His name is Georgie. And he is only eight weeks old and he's already a Tennessee resident. How cool is that?
Leahy: That's very cool. You've been out there as a prominent Black conservative woman who's just not taking any guff from the liberals and you've become a target. And you masterfully punch back in a way that is fun to watch. And that's why one of the reasons why you're so popular and why I think your show is going to be such a success. What has changed in your life now that your mom?
Owens: People ask that question and I think that the correct answer to that is that all of these topics just bear more weight to them. And what I mean by that is that you can obviously debate political topics just on the merit of the discussion. But when you have a child you realize that how we decide these debates.
You know who ends up winning these debates is really determining the future of how your children are going to be raised. I often ask myself is my son going to be raised in the same America that I grew up in? And really with the Democrats at the wheel, the answer is no. And so everything becomes so much more severe and you just want to give it your absolute all when it comes to informing listeners and saying to people this is really not okay where we're headed.
And we need to sort of stop this train which is falling off of the tracks at the moment. So I definitely think these discussions have just become so much more real to us. And I definitely want to give it my absolute all to make sure that we don't lose America and we don't lose this country.
Leahy: When we come back after the break with Candace Owens we'll ask the big question, which is did she watch the Joe Biden event last night, and what was her reaction? So Candace, think about that over the break. I'm sure you've thought about that quite a bit.

redpajama_set_name: RedPajamaCommonCrawl


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Robert A. Collins
Known for Joel D. Wynkoop's The Other Side (2011), Past Due (2013), Vater Entertainment Live (2014)
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Clinical Trials About "A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia"
Home » Clinical Trials » Clinical Trials About "A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia"
We list hundreds of Clinical Trials about "A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia" on BioPortfolio. We draw our references from global clinical trials data listed on ClinicalTrials.gov and refresh our database daily.
More Information about "A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia" on BioPortfolio
We have published hundreds of A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia news stories on BioPortfolio along with dozens of A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia Clinical Trials and PubMed Articles about A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia Companies in our database. You can also find out about relevant A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia Drugs and Medications on this site too.
Search Clinical Trials Only by Keyword: Relevance Date
Showing "Phase Single Open label Study Ofatumumab GSK1841157 Patients" Clinical Trials 1–25 of 50,000+
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A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia
Ofatumumab is an IgG1κ fully human monoclonal antibody (mAb) that specifically recognizes an epitope on the human differentiation antigen CD20 molecule. In vitro and in vivo studies demonstrated that ofatumumab depletes CD20 positive (CD20+) B cells through complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC), which results in the antitumour effect. This is an open-label study to evaluate safety, tolerability, efficacy and PK profil...
Study to Evaluate SC Route of Administration of Ofatumumab in RA Patients
This study will examine the safety and tolerability, PK and PD of subcutaneously administered GSK1841157 in patients with RA on stable dose Methotrexate. The study comprises a single dose escalation/de-escalation phase to investigate the minimal efficacious dose based on PD markers with an acceptable safety profile.
Sequential Regimen of Bendamustin-Debulking Followed by Ofatumumab and Ibrutinib in CLL Patients (CLL2-BIO)
A prospective, open-label, multicentre phase-II trial to evaluate the efficacy and safety of a sequential regimen of bendamustine followed by ofatumumab and ibrutinib followed by ibrutinib and ofatumumab maintenance in CLL patients.
An Open-Label Phase 2 Study of Ofatumumab (Arzerra) in Combination With Oral GSK2110183 in the Treatment of Relapsed and Refractory Chronic Lymphocytic Leukemia (CLL)
This is a phase 2, open-label, single institution trial of combination of intravenous (IV) ofatumumab and oral GSK2110183 in patients with relapsed or refractory Chronic Lymphocytic Leukemia (CLL). Patients must have received at least one prior line of therapy containing fludarabine (single-agent or combination therapy). During the initial 6 months Treatment Phase, ofatumumab will be administered weekly for 8 doses, then once every 4 week cycle for an additional 4 doses (dos...
Patients With Relapsed or Refractory Diffuse Large B Cell Non Hodgkin Lymphomas
This is a phase II open label study that looks at the efficacy and toxicity of Ofatumumab monotherapy in patients with relapsed and/or refractory DLBCL. Patients will receive weekly infusions of Ofatumumab of 1000 mg each for 8 weeks (induction phase) followed by continuing the study drugs every other week in subsequent cycles (maintenance phase). Each 4 weeks of therapy will be calculated as one cycle. Treatment will continue until disease progression, toxicity, patient's wit...
Single Agent Ofatumumab Vs. Single Agent Rituximab in Follicular Lymphoma Relapsed After Rituximab-Containing Therapy
This is a multi-center, parallel, active comparator controlled, open-label, randomized (1:1) phase III study of single agent ofatumumab compared to single agent rituximab in subjects with rituximab-sensitive grade 1, 2, and 3A follicular lymphoma that has relapsed at least 6 months after completing treatment with single agent rituximab or a rituximab-containing regimen. Subjects must have attained a Complete Response or Partial Response to their last prior rituximab containing...
Long-Term Extension Study of Ofatumumab in Subjects With Pemphigus Vulgaris
This study is designed as a multi-country, multicenter, open label extension to Phase III trial OPV116910. The primary objective is to provide continued treatment with ofatumumab subcutaneous (SC) for eligible subjects who complete the OPV116910 trial in order to obtain further long term safety and tolerability information in subjects with pemphigus vulgaris receiving ofatumumab SC every 4 weeks (wk).
Ofatumumab in Japanese Patients With CD20 Positive Follicular Lymphoma or Chronic Lymphocytic Leukemia
This is an open-label study to evaluate safety, tolerability, efficacy and PK profile of ofatumumab monotherapy in Japanese follicular lymphoma (FL) or chronic lymphocytic leukemia (CLL) patients. subject will receive ofatumumab 8 weekly infusions.
A Phase 3 Extension Study of Duvelisib and Ofatumumab in Patients With CLL/SLL Previously Enrolled in Study IPI-145-07
A Phase 3 (extension) clinical trial to examine the efficacy of IPI-145 monotherapy or ofatumumab monotherapy in subjects with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) who experienced disease progression after treatment with IPI-145 or Ofatumumab in Study IPI-145-07.
A Phase II Trial of Ofatumumab in Subjects With Waldenstrom's Macroglobulinemia
Given the tolerability and efficacy of ofatumumab in follicular lymphoma and Chronic Lymphocytic Leukemia, and the need to improve therapy for patients with WM utilizing a non-myelosuppressive agent this phase II trial of ofatumumab is being initiated in patients with Waldenstrom's Macroglobulinemia (WM).
Ofatumumab Cardiac Repolarization (QTc) Study in Fludarabine-Refractory Chronic Lymphocytic Leukemia Subjects
Ofatumumab is a fully-human monoclonal antibody that exhibits high binding affinity to an antigen on the surface of B lymphocytes. Antigen engagement by ofatumumab results in maximal B-cell killing through complement-dependent cytotoxicity and antigen-dependent cellular cytotoxicity in both antigen high- and low-expressing cells. Recent research has shown that ofatumumab-dependent B-cell depletion provides clinical benefit to subjects with CD20-positive cancers such as chroni...
A 12 Week Randomized Open Label Parallel Group Multicenter Study to Evaluate Bioequivalence of 20 mg Subcutaneous Ofatumumab Injected by Pre-filled Syringe or Autoinjector in Adult RMS Patients
The primary purpose of this study is to demonstrate pharmacokinetic bioequivalence of ofatumumab injected by Pre-filled Syringe (PFS) versus Auto-Injector (AI) devices and thereby establish a bridge between the ongoing Phase 3 program and the to-be-marketed drug-device combinations
Efficacy and Safety of Ofatumumab Compared to Placebo in Patients With Relapsing Multiple Sclerosis Followed by Extended Treatment With Open-label Ofatumumab
The study will provide efficacy, safety, tolerability and pharmacokinetics data for ofatumumab 20 mg subcutaneous injections every 4 weeks compared with placebo for 24 weeks in patients from Japan and the other countries and also provide the extended efficacy, safety, tolerability and pharmacokinetics data.
PH2 Trial in Patietns With Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) With a Combination of Bendamustine & Ofatumumab
Investigational Drugs: Ofatumumab (Azerra) + bendamustine (Trenda) Route of Administration: Intravenous (IV) Hypothesis: This study is designed to assess the toxicity and overall response rate. Ofatumumab is a fully human monoclonal antibody (A type of protein made in the laboratory that can bind to substances in the body, including tumor cells) that shows promising activity in the treatment of CLL as a single agent. It is thought that by combining it wit...
Ofatumumab With Fludarabine and Cyclophosphamide in B-CLL Patients
To investigate the safety and efficacy of two dose regimes of ofatumumab in combination with chemotherapy in previously untreated patients with B-CLL
Bendamustine in Combination With Ofatumumab, Carboplatin and Etoposide for Refractory or Relapsed Aggressive B-Cell Lymphomas
The Phase I part of the study will apply to identify dose-limiting toxicities (DLT) and to define maximum-tolerated dose (MTD) for a new chemoimmunotherapy combination of bendamustine, ofatumumab, carboplatin, and etoposide in patients with Non Hodgkin's lymphoma whose disease has progressed or has recurred after prior chemotherapy. The Phase II part of the study will be a single-arm, open-label study in which all patients will receive combination bendamustine, ofatumumab, car...
Phase II Study of Ofatumumab Plus ICE or DHAP Chemotherapy Regimen in Relapsed/ Refractory DLBCL
The purpose of this study is to evaluate the safety and efficacy of ofatumumab used in combination with ICE or DHAP salvage chemotherapy regimens in subjects with relapsed or refractory DLBCL who are eligible for autologous stem cell transplant.
Ofatumumab Retreatment and Maintenance Treatment in CLL Patients
The purpose of the trial is to investigate the efficacy and safety of ofatumumab retreatment and maintenance in patients with chronic lymphocytic leukemia who have previously responded or had disease stabilization after ofatumumab in an ongoing trial (Hx-CD20-406).
Ofatumumab Plus Bendamustine in Frontline and Relapsed Chronic Lymphocytic Leukaemia (CLL)
This is a Phase II, open label, single arm, multi-centre study investigating the safety and efficacy of ofatumumab plus bendamustine in subjects with untreated or relapsed CLL. Each subject from the screening phase who is willing to participate in the study and is found eligible according to the inclusion and exclusion criteria will enter the treatment phase and will receive a maximum of 6 Cycles of study treatment (ofatumumab plus bendamustine). All subjects will receive 3 Cy...
Protocol GELLC-7: Ibrutinib Followed by Ibrutinib Consolidation in Combination With Ofatumumab
Based on the promising results obtained with ibrutinib as single agent, the results obtained with ibrutinib in combination with ofatumumab in a previous phase I/IIb study (Jaglowski 2015), and since data from in vitro studies do not support a synergistic effect of the combination of ibrutinib and anti-CD20 mAbs, we propose a chemotherapy-free combined strategy based on ibrutinib monotherapy as front line treatment for patients with CLL, with the addition of a consolidation phas...
Ofatumumab Dose-finding in RRMS Patients
Ofatumumab is a fully human monoclonal antibody that targets a unique epitope on the CD20 molecule on the surface of B lymphocytes. Ofatumumab has been administered to several more than 500 patients in various indications. The purpose of the trial is to investigate the safety (Part A) and the dose response of three doses of ofatumumab compared to placebo (Part B) in subjects with Relapsing Remitting Multiple Sclerosis (RRMS). The dose response as well as the effect of redosing...
Investigating Clinical Efficacy of Ofatumumab in Adult RA Patients Who Had an Inadequate Response to TNF-α Antagonist Therapy
The purpose of this study is to determine the effect of ofatumumab combined with methotrexate in patients with rheumatoid arthritis who have responded inadequately to previous TNF-α inhibitor therapy
A Phase 3 Study of Duvelisib Versus Ofatumumab in Patients With Relapsed or Refractory CLL/SLL (DUO)
A Phase 3 clinical trial to examine the efficacy of IPI-145 monotherapy versus ofatumumab monotherapy in subjects with relapsed or refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL).
Ofatumumab/Methylprednisolone Followed by Ofatumumab/Lenalidomide for Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
The main purpose of this study is to see if the combination of ofatumumab with high dose methylprednisolone followed by additional treatment with ofatumumab and lenalidomide can help people with relapsed or refractory CLL/SLL get rid of their CLL/SLL for a long period of time. Researchers also want to find out if the combination of ofatumumab with methylprednisolone followed by additional treatment with ofatumumab and lenalidomide is safe and tolerable.
Buparlisib and Ofatumumab or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
This phase I trial studies the side effects and best dose of buparlisib when given together with ofatumumab or ibrutinib in treating patients with chronic lymphocytic leukemia that has returned after a period of improvement or does not respond to treatment. Buparlisib and ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as ofatumumab, may block cancer growth in different ways by targeting certain c...
More From BioPortfolio on "A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia"


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George C. Williams and Evolutionary Literacy
Author: Michael P. Cohen
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In this book, a case study of a humanistic reading of an essential evolutionary theorist, George C. Williams (May 12, 1926–September 8, 2010), the author contends that certain classic works of evolutionary theory and history are the most important nature writing of recent times. What it means to be scientifically literate—is essential for humanistic scholars, who must ground themselves with literary reading of scientific texts. As the most influential American evolutionary theorist of the second half of the twentieth century, Williams masters critique, frames questions about adaptation and natural selection, and answers in a plain, aphoristic writing style. Williams aims for parsimony—to "recognize adaptation at the level necessitated by the facts and no higher"—through a minimalist writing style. This voice articulates a powerful process that operates at very low levels by blind and selfish chance at the expense of its designed products, using purely trial and error.
Reading Human Nature
Author: Joseph Carroll
Showcases the latest developments in literary Darwinism, a powerful approach that integrates evolutionary social science with literary humanism.
The Transcendent Dynamic
Author: David Birnbaum
Publisher: New Paradigm Matrix
Summa Metaphysica proposes a comprehensive and integrated metaphysical structure – a new paradigm. Summa I: God and Evil: Religious Man (published 1988) and Summa II: God and Good: Spiritual Man (first launched 2005 online) comprise Birnbaum's Summa Metaphysica series. The author has proposed that one fundamental concept – and one fundamental concept alone – Quest for Potential∞ (recursive to the infinite power) – ignited – and drives – the cosmos – and the integral infinite divine. Building upon his 1988 treatise, in Summa II: God and Good: Spiritual Man (17 years later) the author lays out his overarching metaphysical structure in very significantly greater scope, depth, breadth and texture. Summa III: The Transcendent Dynamic: Secular Man offers a metaphysics for 'Everyman' – de-linked from any spirituality or religious aspects. It might best be classified as 'scientific metaphysics'. It Is anchored In a creative finesse of science and logic. Birnbaum's paradigm is non–linear, as opposed to the linearity of the great bulk of Western philosophy. It is non– circular, as opposed to the circularity of much of Eastern philosophy. Rather, Birnbaum's paradigm is what the author refers to as a "spiral/reflexive" dynamic (elucidated in the text). The author proposes that this Quest for Potential∞ paradigm more elegantly explains the dynamics of the cosmos – and of life, in particular – than alternate propositions. According to Birnbaum, only the full plethora of potentials – and the quest thereof – could have ignited the cosmos. The combined potentials for love, life, intellectuality, spirituality and, indeed, for an infinitely Perfect Divine, ignited, birthed, nurtured, and projected the cosmos onward on its quest towards infinity. 'Extraordinariation,' according to the author, is the overarching goal. Thomas Aquinas wrote Summa Theologica c. 1273 within a Christian context. The Summa Metaphysica series, proposing an original, dynamic, overarching, and integrated metaphysics, is crafted within a Jewish context seven hundred years later.
Reading History Sideways
Author: Arland Thornton
Publisher: University of Chicago Press
European and American scholars from the eighteenth through the mid-twentieth centuries thought that all societies passed through the same developmental stages, from primitive to advanced. Implicit in this developmental paradigm—one that has affected generations of thought on societal development—was the assumption that one could "read history sideways." That is, one could see what the earlier stages of a modern Western society looked like by examining contemporaneous so-called primitive societies in other parts of the world. In Reading History Sideways, leading family scholar Arland Thornton demonstrates how this approach, though long since discredited, has permeated Western ideas and values about the family. Further, its domination of social science for centuries caused the misinterpretation of Western trends in family structure, marriage, fertility, and parent-child relations. Revisiting the "developmental fallacy," Thornton here traces its central role in changes in the Western world, from marriage to gender roles to adolescent sexuality. Through public policies, aid programs, and colonialism, it continues to reshape families in non-Western societies as well.
Encyclopedia of Evolution
Author: Stanley A. Rice
Publisher: Infobase Publishing
Evolutionary science is not only one of the greatest breakthroughs of modern science, but also one of the most controversial. Perhaps more than any other scientific area, evolutionary science has caused us all to question what we are, where we came from, and how we relate to the rest of the universe. Encyclopedia of Evolution contains more than 200 entries that span modern evolutionary science and the history of its development. This comprehensive volume clarifies many common misconceptions about evolution. For example, many people have grown up being told that the fossil record does not demonstrate an evolutionary pattern, and that there are many missing links. In fact, most of these missing links have been found, and their modern representatives are often still alive today. The biographical entries represent evolutionary scientists within the United States who have had and continue to have a major impact on the broad outline of evolutionary science. The biographies chosen reflect the viewpoints of scientists working within the United States. Five essays that explore interesting questions resulting from studies in evolutionary science are included as well. The appendix consists of a summary of Charles Darwin's Origin of Species, which is widely considered to be the foundational work of evolutionary science and one of the most important books in human history. The five essays include: How much do genes control human behavior?What are the ghosts of evolution?Can an evolutionary scientist be religious?Why do humans die?Are humans alone in the universe
Body by Darwin
Author: Jeremy Taylor
We think of medical science and doctors as focused on treating conditions—whether it's a cough or an aching back. But the sicknesses and complaints that cause us to seek medical attention actually have deeper origins than the superficial germs and behaviors we regularly fault. In fact, as Jeremy Taylor shows in Body by Darwin, we can trace the roots of many medical conditions through our evolutionary history, revealing what has made us susceptible to certain illnesses and ailments over time and how we can use that knowledge to help us treat or prevent problems in the future. In Body by Darwin, Taylor examines the evolutionary origins of some of our most common and serious health issues. To begin, he looks at the hygiene hypothesis, which argues that our obsession with anti-bacterial cleanliness, particularly at a young age, may be making us more vulnerable to autoimmune and allergic diseases. He also discusses diseases of the eye, the medical consequences of bipedalism as they relate to all those aches and pains in our backs and knees, the rise of Alzheimer's disease, and how cancers become so malignant that they kill us despite the toxic chemotherapy we throw at them. Taylor explains why it helps to think about heart disease in relation to the demands of an ever-growing, dense, muscular pump that requires increasing amounts of nutrients, and he discusses how walking upright and giving birth to ever larger babies led to a problematic compromise in the design of the female spine and pelvis. Throughout, he not only explores the impact of evolution on human form and function, but he integrates science with stories from actual patients and doctors, closely examining the implications for our health. As Taylor shows, evolutionary medicine allows us think about the human body and its adaptations in a completely new and productive way. By exploring how our body's performance is shaped by its past, Body by Darwin draws powerful connections between our ancient human history and the future of potential medical advances that can harness this knowledge.
From Darwinian Metaphysics Towards Understanding the Evolution of Evolutionary Mechanisms
Author: Momme von Sydow
Publisher: Universitätsverlag Göttingen
"Although Charles Darwin predicted that his theory 'would give zest to ... metaphysics, ' even he would be astonished at the variety of paths his theory has in fact taken. This holds with regard to both gene-Darwinism, a purified Darwinian approach biologizing the social sciences, and process- Darwinism found in the disciplines of psychology, philosophy of science, and economics. Although Darwinism is often linked to highly confirmed biological theories, some of its interpretations seem to profit from tautological claims as well, where scientific reputation cloaks ideological usage. This book discusses central tenets of Darwinism historically as well as systematically, for example the history of different Darwinian paradigms, the units-of-selection debate, and the philosophical problem of induction as basis of metaphysical Darwinism. Crucially the book addresses the Darwinian claim that evolution is governed by an immutable and unrelentingly cruel law of natural selection. Paradoxically, Darwins theory is a static, non-evolutionary theory of evolution. The current book sketches the historical background and provides suggestions that may help to replace this approach by the idea of an evolution of evolutionary mechanisms (see Escher's 'Drawing Hands' on the cover). This view even suggests a tendency to overcome the blindness of the knowledge acquisition of primordial Darwinian processes and allows for some freedom from external environments. This book first develops a radically Darwinian approach, then criticises this approach from within. Even Darwinism has a tendency to transcend itself. Although the book addresses several empirical issues, it does not challenge particular findings. Instead it builds on many insights of Darwinism and provides a proposal for interpreting known empirical evidence in a different light. It should help pave the way for further developing an understanding of nature that transcends Darwinian metaphysics"--Publisher's description.
Author: Peter D. Gluckman
This is the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.
Evolution and Ethics
Author: James G. Paradis
T. H. Huxley (1825-1895) was not only an active protagonist in the religious and scientific upheaval that followed the publication of Darwin's theory of evolution but also a harbinger of the sociobiological debates about the implications of evolution that are now going on. His seminal lecture Evolution and Ethics, reprinted here with its introductory Prolegomena, argues that the human psyche is at war with itself, that humans are alienated in a cosmos that has no special reference to their needs, and that moral societies are of necessity in conflict with the natural conditions of their existence. Seen in the light of current understanding of the mechanisms of evolution, these claims remain as controversial today as they were when Huxley proposed them. In this volume George Williams, one of the best-known evolutionary biologists of our time, asserts that recent biological ideas and data justify a more extreme condemnation of the "cosmic process" than Huxley advocated and more extreme denial that the forces that got us here are capable of maintaining a viable world. James Paradis, an expert in Victorian studies, has written an introduction that sets the celebrated lecture in the context of cultural history, revealing it to be an impressive synthesis of Victorian thinking, as well as a challenge to eighteenth-century assumptions about the harmony of of nature. With Huxley's lecture as a focal point, the three parts of this book unite philosophy and science in a shared quest that recalls their common origins as systems of knowledge. Originally published in 1989. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Science in the Twentieth Century
Author: John Krige
With over forty chapters, written by leading scholars, this comprehensive volume represents the best work in America, Europe, and Asia. Geographical diversity of the authors is reflected in the different perspectives devoted to the subject, and all major disciplinary developments are covered. There are also sections concerning the countries that have made the most significant contributions, the relationship between science and industry, the importance of instrumentation, and the cultural influence of scientific modes of thought. Students and professionals will come to appreciate how, and why, science has developed - as with any other human activity, it is subject to the dynamics of society and politics.
The Edge of Evolution
Author: Ronald Edwards
In this interdisciplinary work, author Ron Edwards offers an innovative rereading of H. G. Wells' "The Island of Dr. Moreau." Edwards utilizes his twenty-five years in biology and the ethics of animal research to examine the bioethical implications of Wells' work and its relevance to contemporary scientific and philosophical discussions. He tackles the myth of human exceptionalism, the notion that we are fundamentally different from the rest of the animal kingdom. We must view ourselves, he argues, not as from animals, but as animals. The approachable tone is suitable for a wide audience of the scientifically curious. At the same time, great care is given to providing an accurate and considered treatment of the technical aspects of the novel, including the scientific plausibility of Dr. Moreau's experiment. Never before have Wells' ideas been examined in such detail by an evolutionary biologist with the author's considerable experience. The implications are far-reaching, touching on key topics in animal rights, evolution, and the relationship between religion and science. Its approachability and dedication to technical accuracy produces a unique perspective on Wells' classic. Anyone with an interest in confronting some of the central issues of human existence through the lens of fiction will be rewarded with an original and thought-provoking work.
Evolution, Morality and the Fabric of Society
Author: R. Paul Thompson
Recent interest in the evolution of the social contract is extended by providing a throughly naturalistic, evolutionary account of the biological underpinnings of a social contract theory of morality. This social contract theory of morality (contractevolism) provides an evolutionary justification of the primacy of a moral principle of maximisation of the opportunities for evolutionary reproductive success (ERS), where maximising opportunities does not entail an obligation on individuals to choose to maximise their ERS. From that primary principle, the moral principles of inclusion, individual sovereignty (liberty) and equality can be derived. The implications of these principles, within contractevolism, are explored through an examination of patriarchy, individual sovereignty and copulatory choices, and overpopulation and extinction. Contractevolism is grounded in evolutionary dynamics that resulted in humans and human societies. The most important behavioural consequences of evolution to contractevolism are reciprocity, cooperation, empathy, and the most important cognitive consequences are reason and behavioural modification.
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Service Life Prediction of Polymeric Materials
Life in Occupied Guernsey
The Nature of Statistical Learning Theory
Stone Fox Bride
England and the Crusades, 1095-1588
Chin Na in Groundfighting
Teaching Embodied
Biographies of Homeopathic Physicians, Volume 17
North Shore Railway [microform]
Small Steps, Big Changes
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Mr Gunjan Sharma > Volterra Fietta > London, England > Lawyer Profile
Volterra Fietta Offices
Volterra Fietta
8 MORTIMER STREET, FITZROY PLACE
W1T 3JJ
Mr Gunjan Sharma
+44 207 380 3531 gunjan.sharma@volterrafietta.com View profile View profile
Counsel at Volterra Fietta
Gunjan Sharma is a highly qualified and experienced New York lawyer who specialises in international dispute resolution and public international law. He represents clients at the highest levels of practice. He is Counsel at Volterra Fietta and joined the firm in October 2018. Previously, Gunjan was a senior associate in the international arbitration and litigation group of Skadden Arps's New York office.
Gunjan's experience includes representing States before the International Court of Justice; representing private entities and States in investor-State arbitrations; and acting as counsel before a wide range of US courts. This includes the US Court of Appeals of the Second Circuit, several federal district courts and the courts of the State of New York. A sovereign State also appointed him as an expert witness on a matter of diplomatic and State immunity before the courts of a European country.
For example, Gunjan was a senior associate in the firm's representation of the Democratic Republic of Congo, Kenya and the United Arab Emirates before the International Court of Justice. Gunjan is also a key member of the teams that: (i) defend the Arab Republic of Egypt in an ICSID arbitration brought by Al Jazeera Media Network; (ii) advise Norgold SE in relation to a wide range of public international law matters; and (iii) successfully defended the Republic of Lithuania in an ICSID arbitration brought by Mr Olegs Roščins regarding measures taken against bank accounts as the result of a money-laundering investigation. In the latter case, following an investigation of the underlying facts by counsel, the firm filed a motion for preliminary dismissal of the proceeding for manifest lack of legal merit under the ICSID Arbitration Rules 41(5) and 41(6), causing the Claimant to abandon its case.
Gunjan's extensive disputes resolution experience is strengthened by a significant level of non contentious and transactional experience. Gunjan routinely advises States and private parties on front-page-news issues of international law. He has advised States as legal counsel during treaty negotiations and on boundary delimitation matters, in both the Caribbean Basin and Africa. He represented the Government of Barbados in its treaty negotiations with the Government of Trinidad and Tobago in relation to a transboundary unitisation agreement. Gunjan also represented the interests of a major company before the US Trade Representative during the TPP and USMCA negotiations. He has also advised clients on numerous issues in over 300 large commercial deals, including in the oil and gas, alternative energy, construction and insurance industries.
Gunjan publishes academic writings and speaks on a wide variety of international legal topics. His work has been cited by a number of influential publications and entities, including the United States Congressional Research Service.
Gunjan obtained a Juris Doctor from the New York University School of Law in 2009. In 2006, he obtained a Bachelor of Science in Foreign Service (International Law, Politics and Ethics), with a Certificate in Asian Studies, from the Walsh School of Foreign Service at Georgetown University, where he was distinguished as a Krogh Honors Medallion Scholar.
Gunjan also has a strong commitment to equality and justice in the criminal justice system. He was a Litigation Fellow at the Innocence Project, a charitable organisation dedicated to exonerating wrongfully convicted individuals by using DNA evidence. As a law student, he worked in Alabama to oppose systemic inequality in the US criminal justice system with the Equal Justice Initiative, an influential charity based in Montgomery, Alabama.
In 2020, the Legal 500 listed Gunjan under the "Rising Star" category for public international law. Peers and clients referred to Gunjan as a "future star in the public international law area for sure" who is "very professional", "quick and very easy in communication" and has "fantastic drafting skills".
New York City Bar Association; London Court of International Arbitration; Association of International Petroleum Negotiators
Member of the New York Bar, First Appellate Division (2010)
New York University School of Law, Juris Doctor (2009)
Georgetown University Walsh School of Foreign Service: Bachelor of Science in Foreign Service (International Law, Institutions and Ethics) (2006); Certificate in Asian Studies (2006); Krogh Honors Medallion Scholar (2006)
London > Dispute resolution > International arbitration
Housing lawyers who are 'absolutely at the highest level', the investment treaty arbitration practice at specialist public international law (PIL) firm, Volterra Fietta represents both states and foreign investors. The firm is also increasingly involved in commercial arbitrations. Robert Volterra
is an investment treaty arbitration expert; Graham Coop focuses on energy, natural resources and infrastructure-related matters; and Peter Flint is 'detail oriented'. Counsel Gunjan Sharma is a PIL and international dispute resolution specialist, while associate Angela Ha is 'very thorough'.
London > Dispute resolution > Public international law
(Rising stars)
Gunjan Sharma – Volterra Fietta
'Without doubt the leading firm in public international law', Volterra Fietta's large PIL practice acts for private entities, states and international organisations across the full range of PIL work, including International Court of Justice (ICJ) cases, maritime boundary claims, and investment treaty and International Centre for Settlement of Investment disputes (ICSID) arbitrations. The firm also fields specialists in state immunity cases, the laws of war and international humanitarian law, along with international human rights, state responsibility, and WTO and international trade law. The 'best public international lawyer around', Robert Volterra
assists with a wide range of PIL issues; Graham Coop is particularly focused on the energy, natural resources and infrastructure sectors; and the experience of recently elevated partner Peter Flint includes acting for governments and commercial parties in international disputes. Recently promoted counsel Gunjan Sharma, and associates Angela Ha and Jehad Mustafa, all have extensive PIL experience.
Public international law - London > Dispute resolution
Rising stars - London > Dispute resolution > Public international law
International arbitration - London > Dispute resolution
Dispute resolution > Public international law
Dispute resolution > International arbitration


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Contest Maleficent: Mistress of Evil
Win 'Maleficent: Mistress of Evil' on Blu-ray
January 6, 2020Ben MK
This winter, go beyond the fairy tale. Angelina Jolie and Michelle Pfeiffer go head-to-head in Disney's Maleficent: Mistress of Evil, and you could win a copy on Blu-ray!
Directed by Joachim Rønning, "Maleficent: Mistress of Evil" carries on the story of Disney's most iconic villain. The years have been kind to Maleficent and Aurora. Their relationship, born of heartbreak, revenge and ultimately love, has flourished. Yet hatred between man and the fairies still exists. Aurora's impending marriage to Prince Philip is cause for celebration as the wedding serves to unite the Kingdom of Ulstead and the neighboring Moors. But, when an unexpected encounter introduces a powerful new alliance, Maleficent and Aurora are pulled apart to opposing sides in a Great War, testing their loyalties and causing them to question whether they can truly be a family. — Synopsis provided courtesy of Walt Disney Studios Canada
Maleficent: Mistress of Evil is now available on Digital HD and is available on 4K Ultra HD, Blu-ray & DVD January 14th.
Via Facebook: LIKE & FOLLOW our Facebook page and leave a COMMENT on the Facebook contest post to name Michelle Pfeiffer's character in the film. Click here to enter.
Via Email: EMAIL thereelroundup@gmail.com using the subject line 'Enter Me to Win Maleficent: Mistress of Evil on Blu-ray', and provide your full name, phone number and mailing address in the body of the email.
Contest open to legal residents of Canada aged 18 years or older at the time of entry, and closes Monday, January 13, 2020 at 11:59 PM Eastern Time. One prize per household. Odds of winning are dependent on the total number of entries received. Winner(s) will be selected at random, and will be contacted via Twitter direct message, Facebook message or email, depending on the method(s) of entry. Should a winner be disqualified or fail to respond in a timely manner in cases where further information is required from him/her to redeem the prize, The Reel Roundup™ reserves the right to draw another winner in his/her place. By participating in this contest, all entrants agree to be bound by these rules and regulations. The Reel Roundup™ accepts no legal liability in relation to the operation of this contest.


Transylvania, a Romanian region, has a long herbalism tradition. In the past, medicinal plants were used for divination and to treat diseases, but over time part of the knowledge was lost.
The elders were the ones mostly still preserving this precious knowledge, which nowadays is being rediscovered thanks to people like Emese Csíki, who in 2006 decided to leave her office job to practice herbalism in the small rural town of Szentábrahám (Avrămești) in Transylvania.
Her herb garden, nicknamed 'Wondergarden', consists of about sixty different medicinal plants, grown with traditional organic methods. Emese and her family live in a 300 year old mansion in one hectare of land, close to nature.
The herbalist job, or "gyógynövénytermesztő" in the local language, is based on respect for the environment and on the principles of sustainable agriculture. The herbs are collected, dried and processed by hand, to prepare wellness teas and traditional Transylvania spices. The ancient knowledge is thus used to appease the taste and to promote wellness.
Bunching onion, hyssop, garlic, dill and cornflower are just some of the spices traditionally used by the Szeklers (Székelyek), subgroup of the hungarian people living in Transylvania, mostly in the counties of Harghita, Covasna and Mureș. Legend says that Csaba, son of the Hun Emperor Attila, led the Szeklers to the Carpathians, where they're still waiting for their protector Csaba to come back.
One of Emese's teas carries her name, but also that of a legendary figure: Emese, mother of Prince Álmos. "Emese's dream" is a delicate and feminine tea, whose rose, calendula, elderberry and linden flower flavours invoke the maternal figure. According to the hungarian legend, Emese saw in her dreams the Turul, a mythological bird similar to a big falcon, who told her that her son would become the founder of a great dynasty.
By contacting Emese on her website or facebook page you can organize guided tours to her herb garden, taste her teas, try the traditional cuisine with spices and learn the techniques of organic farming. From specialists interested in medicinal plants to children wanting to spend a day outdoors, the herbalist's garden offers interesting activities for people of all ages.
Unlike Emese, Csekefalva's herbalist Noemi Moldovan-Szeredai started getting passionate about medicinal herbs when she was in high-school. Her interest in herbalism kept growing while she wandered in the fields looking for plants with a traditional book about regional herbs.
At the end of her studies, she moved to Csekefalva's village in Harghita County in order to follow her profession as a minister. However, she continued pursuing her herbalism hobby.
She collects herbs to make teas and fruits for jams and syrups. Noemi makes jams from her own fruit trees: plum, sour cherry, dogberry, quince, apple, pear, peach, apricot and strawberry.
In 2012 she and her husband decided to plant lavender. Now she produces teas, syrups and jams, that she usually mixes with herbs or fruit like in her apricot and lavender jam. In addition she makes goat milk soaps, closet and drawer sachets, little pillows and essential oils.
Lavender fields and fruit trees maintenance, herbs collection and products making, require a lot of passion, patience and workforce. Noemi believes in herbalism as a good disease prevention measure. She is committed to spread her knowledge in her community and in the surroundings. That is why she often participates in festivals and local markets.
It is possible to plan a visit to see Noemi's garden and lavender fields and to taste her homemade lavender cookies. Tourists or locals can buy her products at events or markets (check the facebook page), after the guided tour or just by contacting her via phone (+400724071268).


For the ninth year, the Aethelmarc Rapier Army got a tic-tac-toe board made of four crossed rapiers. The token can be sewn onto a favor through the heads of the rapiers. On the back, there are nine small roses and one tiny Maltese cross.
Hooray we've all been talking, but let's make sure we're talking about the right thing….
Rozi on So, now what?
Janna on So, now what?


Pio Rahner was born in Offenburg. He lives and works in Bremen. Pio Rahner's works oscillate between conceptual photography and installation-sculpture. One of the main focuses of his practice is balancing his concentration on a specific object with the realization, production and positioning of the object in its surroundings. At bb15 he is preparing a new series that examines the architecture of the space and explores themes of protection and cosiness.


I was using the windows desktop app this morning with several items bid awaiting the close. I opened the first item to edit the bid price, and when I went to save it, the app just sat there with the spinning circle, and never updated. After about 10 minutes, I opened the website in a browser, and that item was GONE from the list. I reentered it on the web with the new price.
"Error receiving data (12002). Operation timed out."
I prefer using the desktop app because it updates the time - If I use the website, it doesn't, and I have to refresh my browser window to do it.


Tried the lychee rose, mango passion, Japanese yuzu and durian. Love them all! The sobert taste refreshing!
I thought that those colourful assortment in display were macarons but they turned out to be softserve ice cream capsules. A machine was used to extract the softserve out and the two glasses of ice cream in the picture was a result of processing from the machine.
We tried the blueberry yogurt and royal earl grey. They were dense and did not melt fast which is unconventional for a softserve. My favourite is the earl grey for its rich aromatic bergamot tea profile.
Not to be mistaken for giant macarons! These capsules contain sugar free gelatos/sorbets to be squeezed out and then twirled onto a cup like a soft serve! Enjoyed the icy fine sorbet texture, very refreshing options! Will be back to try something from the gelato and the yogurt range!


A canonical continuation by Sir Arthur Conan Doyle's son, Adrian Conan Doyle and John Dickson Carr. First published in 1954. I love the cover of this 1976 paperback reprint.
Once again, "The game's afoot!"
Sherlock Holmes and Dr. Watson embark on twelve new detective adventures that have been out of print for more than twenty years.
These strange and surprising cases––only hinted at in the famous earlier chronicles––are recorded at last in full. Here is the good Watson, rushing impetuously to the aid of lovely ladies in distress. And Holmes, taking soothing pleasure from his violin while frustrating Scotland Yard's Lestrade at every encounter.
These are, indeed, cases for the connoisseur. No one could have produced them with the authentic Conan Doyle flavor but Sir Arthur's son Adrian. Writing with one of the world's greatest masters of mystery, John Dickson Carr, he has produced a rare casebook to delight and confound Sherlock Holmes fans the world over!


Scale Computing, the market leader in hyperconverged solutions for midsized companies, has announce unprecedented results in hyperconverged virtual machine IO performance using NVM express (NVMe). The lab tests have achieved mean IO latencies as low as 20 microseconds delivered to a guest virtual machine. The unique architecture of Scale's software defined storage engine (SCRIBE) coupled with highly responsive NVMe drives enables this extraordinary performance.


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Solana-Based Prediction Market Uses DeFi Yields to Finance 'No Loss' Betting
Hedgehog's experimental wagers combine prediction markets with stablecoins, decentralized finance and gamification.
By Marc Hochstein
Sep 28, 2021 at 1:00 p.m. UTC
Updated Sep 28, 2021 at 5:08 p.m. UTC
Marc Hochstein
Marc Hochstein is the executive editor of Consensus, CoinDesk's flagship festival. He holds BTC above CoinDesk's disclosure threshold of $1K; marginal amounts of ETH, XMR and ZEC; an Urbit planet (~fodrex-malmev); two ENS domain names (MarcHochstein.eth and MarcusHNYC.eth); and two NFTs from the metal band Gwar.
Follow @MarcHochstein on Twitter
Hedgehog Markets, a fledgling blockchain-based prediction market platform, is testing a novel type of wager where bettors have nothing to lose, at least in theory.
Known as "no-loss markets," these bets combine prediction markets with several big cryptocurrency trends: decentralized finance (DeFi), stablecoins and "play-to-earn" gaming.
To participate, bettors must put up either $100 or $1,000 worth of USDC, a stablecoin designed to hold its value against the U.S. dollar. In return, bettors receive game tokens, which they can wager in a no-loss market.
Gibraltar-based Hedgehog invests the staked USDC with Port Finance, a decentralized finance (DeFi) lending protocol, where the stablecoins earn interest, like a crypto version of a savings account or certificate of deposit (CD). (Hedgehog and Port both run on the Solana blockchain.)
As in normal prediction markets, participants bet on the outcomes of real-world events, in this case soccer and American football games or cryptocurrency price movements. But whereas in the regular markets those who bet wrong lose money, in the no-loss variant losing bettors recover as much USDC as they put in, when the principal on the DeFi deposit is repaid.
Those who bet correctly, meanwhile, win additional game tokens and are ranked by their return on investment (ROI). The yield earned in the DeFi pool will be paid out as prize money split among those who finish at the top of the competition's "ROI leaderboard." Hedgehog is dangling $5,000 to be divided up among the top bettors at the $100 level and $30,000 for distribution to the champions of the $1,000 tier.
Making it 'fun'
Hedgehog's gamified approach follows the success of Axie Infinity, a game running on the Ethereum blockchain that amassed nearly half a million daily active users in its first year.
Gamification "attracts a larger audience than just large-scale traders," Hedgehog founder George Yu, a former Google software engineer, told CoinDesk. One thing Hedgehog considered was "how do you make it fun for people who aren't necessarily degens" – DeFi slang for high rollers.
If the yield from the DeFi pools falls short of the prize amounts, Hedgehog will make up the difference, said Ariana Fariab, who handles growth for Hedgehog. "If the yield ends up being more, [then that's] great, the prize pools will be larger – all yield goes back to users in the form of prize pools."
To be clear: The principal protection on bettors' deposits will rely on the security of the smart contracts, or the software running on the blockchain.
"Depending on the bug or exploit, it is possible for a nefarious actor to take some or all of the funds stored in Hedgehog's smart contracts," notes a disclaimer on Hedgehog's website.
To mitigate this risk, Hedgehog has hired auditing firm Quantstamp to review the code. However, unlike a traditional bank account, the staked USDC will have nothing like FDIC insurance backing it.
"We are not liable for any theft or loss of your cryptographic tokens or property resulting from your use of the services or participation in any markets," warns Hedgehog's terms of service.
Betting on beliefs
Prediction markets are designed to incentivize people with expertise on a topic to tell the world what they really think is going to happen by betting on consequential things like elections or tropical storms or COVID-19 case counts.
Since bettors have money on the line, they will bet on what they truly believe, and if there is money to be made, bona fide experts will have a strong motivation to participate, the thinking goes.
So far, however, this has remained a niche market, due partly to regulatory constraints.
PredictIt, probably the most popular prediction market, is allowed to operate by a no-action letter from the U.S. Commodity Futures Trading Commission (CFTC) on the rationale that it is run for academic research purposes, and it lets traders bet up to only $850 on any one market. Kalshi, another centralized prediction market, has a full-fledged CFTC license and must notify the agency any time it creates a new market.
Hedgehog, whose official legal name is Futarchy Research Limited, raised $3.5 million in July from investors, including the Solana Foundation and crypto billionaire Sam Bankman-Fried's Alameda Research.
It is one of several crypto-based prediction markets that have sprouted up with the goal of replacing centralized intermediaries with smart contracts. Others include Polymarket, Augur and Gnosis.
Hedgehog Markets is not to be confused with Hedgehog Technologies, a startup that lets traders sync various crypto wallets and exchange accounts to get a bird's-eye view of their portfolios, and recently raised its own seed round.
SolanaPrediction MarketsUSDC