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On Wednesday, April 11, at 12:00 p.m. in Room 433, as part of the Speakers from Practice series, all students are invited to attend a panel discussion exploring "Appellate Advocacy." To attend, RSVP here by noon on Tuesday, April 10. Lunch will be provided.
Join us to hear stories and garner advice from an esteemed panel of practicing attorneys and professors, all of whom have extensive experience in appellate advocacy.
Professor Anne Berleman Kearney, principal of Appellate Consulting Group, has been the primary author of briefs for the prevailing party in cases before the United States Supreme Court, the United States Court of Appeals for the Seventh Circuit, and the Illinois and Wisconsin Supreme Courts. Upon graduation from Harvard Law School, Professor Kearney clerked for U.S. District Judge Nicholas Bua (N.D. Ill.).
Professor Jonathan Koenig, Appellate Division Chief in the U.S. Attorney's Office for the Eastern District of Wisconsin, argues frequently before the U.S. Court of Appeals for the Seventh Circuit. He served as Senior Law Clerk to the Honorable Rudolph T. Randa, District Judge, Eastern District of Wisconsin, and, earlier in his career, he served as law clerk to the Hon. John L. Coffey, Circuit Judge, U.S. Court of Appeals for the Seventh Circuit.
James Goldschmidt, attorney at Quarles & Brady in Milwaukee and Harvard Law School graduate, has argued cases before the Wisconsin Supreme Court and the U.S. Court of Appeals for the Seventh Circuit. Attorney Goldschmidt has also briefed cases before the Ninth Circuit and the Federal Circuit.
Marquette University Law School's Speakers from Practice series brings together members of the Law School community and legal professionals to discuss important topics in professional development and various areas of the law.
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Are the loudest of all New World monkeys. They can be commonly found in Costa Rica. Howler monkey usually vocalizes at dusk and these vocalizations are used to mark territory and communicate with other monkeys.
Is one of the most beautiful and deadly snakes of Costa Rica.
Similar in appearance to a turkey. Male Great Curassow is black with yellow knob while female is orange brown color.


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Iraqi training handed over to next rotation
Task Group Taji Rotation 1 (TG Taji-1) formally handed over responsibility for training Iraqi Security Forces at the Taji Military Complex (TMC) in Iraq to Australian and New Zealand personnel of Rotation 2 on Thursday 3 December 2015.
The Transfer of Authority was recognised with a small parade during which outgoing Commander, Colonel Matt Galton handed over mission responsibilities to incoming TG Taji-2 Commander, Colonel Gavin Keating.
COL Galton praised the work of his soldiers during the past seven months and wished Rotation 2 well.
"We have trained over 3600 Iraqi soldiers which is a significant contribution to help the Iraqi Security Forces build their capacity to defeat Daesh," he said.
COL Keating said his team was well poised to build on the successes of TG Taji-1.
"The first rotation developed the mission from scratch and set a very high standard," he said.
"Rotation 2 will maintain this high standard and further develop Australia and New Zealand's relationship with the Iraqi Army and our Coalition partners."
The parade was attended by US Commanding General of the Combined Joint Forces Land Component Command – Iraq (CJFLCC-I), Major General Richard Clarke.
MAJGEN Clarke said TG Taji-1 had made a significant contribution to the regular Iraqi Army's fight against Daesh.
"You are the ones who have been face-to-face with the Iraqi soldiers who are in the fight right now," he said.
"The 71st and 76th Brigades all came through Taji and were trained by you and now they're driving Daesh out of Ramadi and they could not have done that without you.
MAJGEN Clarke awarded COL Galton with a US Bronze Star medal during the parade for his exemplary command of TG Taji-1.
Also recognised during the parade were a number of Arabic language interpreters who supported Rotation 1.
TG Taji is a combined force of Australian and New Zealand Defence Force (NZDF) personnel consisting primarily of soldiers from the Australian Army's 7th Brigade which is based at Gallipoli Barracks in Brisbane.
The Task Group comprises some 300 Australian Defence Force and 105 NZDF personnel.
Iraqi Security Forces will continue to be trained at the TMC as part of the broader international Building Partner Capacity (BPC) mission.
Training ranges from marksmanship and building clearance techniques to obstacle breaching for squad through to company-level operations.
The BPC mission is one component of the Coalition's contribution to Operation Inherent Resolve which consists of more than 60 nations united in an effort to degrade and ultimately defeat Daesh.
TG Taji's BPC contribution is part of Australia's broader Defence contribution to Iraq and Syria known as Operation Okra and includes a Special Operations Task Group and an Air Task Group
Media note:
Imagery is available at: http://images.defence.gov.au/S20153474http://images.defence.gov.au/S20153474
Vision will be fed to the Canberra Press Gallery.
Defence Media (02) 6127 1999
Other Media release content
International military training - positive test results for COVID-19 returned on arrival to Australia
Australia concludes its contribution to the International Maritime Security Construct
Defence congratulates 2020 Australian War College graduates
Chief of Army congratulates 137th graduating class at Duntroon
Royal Australian Air Force and Royal Air Force formalise cooperation

redpajama_set_name: RedPajamaCommonCrawl


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Il Campionato internazionale costruttori gran turismo 1964, la cui denominazione ufficiale è International Championship for GT Manufacturers , è stata la 5ª edizione del Campionato internazionale gran turismo.

Organizzato e regolamentato dalla Federazione Internazionale dell'Automobile, tramite la Commissione Sportiva Internazionale, per le vetture gran turismo senza limiti di cilindrata suddivise in tre divisioni per ognuna delle quali viene assegnato un titolo assoluto. Si aggiudicano i titoli la Abarth-Simca per la Divisione I, la Porsche nella Divisione II, la Ferrari nella Divisione III.

Quattro prove del Campionato sono valide anche per il Challenge mondiale endurance.

Regolamento
Titoli assoluti
Vengono assegnati tre titoli assoluti .:
Campionato internazionale costruttori gran turismo - Divisione I riservato ai costruttori di vetture GT1.
Campionato internazionale costruttori gran turismo - Divisione II riservato ai costruttori di vetture gran turismo GT2.
Campionato internazionale costruttori gran turismo - Divisione III riservato ai costruttori di vetture gran turismo GT3.

Altri titoli
Vengono inoltre assegnati due titoli riservati ai prototipi:
Trofeo internazionale prototipi gran turismo entro 3.0 litri riservato ai costruttori di prototipi P3.0.
Trofeo internazionale prototipi gran turismo oltre 3.0 litri riservato ai costruttori di prototipi P.

Categorie
Al Campionato partecipano tre categorie di vetture raggruppate in divisioni e sottodivisioni in base alla cilindrata per un totale di 14 classi:
Gran turismo: vetture prodotte in numero minimo di 100 esemplari all'anno senza limiti di cilindrata raggruppate in tre divisioni:
GT1: vetture gran turismo divisione I con cilindrata entro 1.3 litri, ulteriormente raggruppate in tre sottodivisioni (GT1/1, GT1/2, GT1/3)
GT2: vetture gran turismo divisione II con cilindrata entro 2.0 litri, ulteriormente raggruppate in tre sottodivisioni (GT2/1, GT2/2, GT2/3)
GT3: vetture gran turismo divisione III con cilindrata oltre 2.0 litri, ulteriormente raggruppate in tre sottodivisioni (GT3/1, GT3/2, GT3/3)

Sport: vetture biposto con carrozzeria aperta o chiusa e motori con cilindrata massima di 3 litri, progettate e costruite per le competizioni in un numero minimo di esemplari ma dotate degli equipaggiamenti per l'uso stradale, suddivise in classi secondo la cilindrata
Prototipi gran turismo: prototipi di vetture gran turismo con carrozzeria aperta o chiusa, senza un minimo di esemplari costruiti, senza limiti di cilindrata massima e suddivisi in classe:
P3.0: prototipi con cilindrata massima entro 3.0 litri
P: prototipi con cilindrata massima oltre 3.0 litri

Costruttori

Resoconto

Risultati

Classifiche

Campionato internazionale costruttori gran turismo divisione I
 Abarth-Simca

Campionato internazionale costruttori gran turismo divisione II
 Porsche

Campionato internazionale costruttori gran turismo divisione III
 Ferrari

Trofeo internazionale prototipi gran turismo
Entro 3.0 litri
 Porsche

Oltre 3.0 litri
 Porsche

Note

Bibliografia

Altri progetti

Collegamenti esterni

Serie e competizioni motoristiche nel 1964

redpajama_set_name: RedPajamaWikipedia


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Thousands of private tutors in Mulgrave3170 can help improve your grades.


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AAPL Login
Research ArticleRegular Article
Diffusion Tensor Imaging in Mild Traumatic Brain Injury Litigation
Hal S. Wortzel, Marilyn F. Kraus, Christopher M. Filley, C. Alan Anderson and David B. Arciniegas
Journal of the American Academy of Psychiatry and the Law Online December 2011, 39 (4) 511-523;
Hal S. Wortzel
Marilyn F. Kraus
Christopher M. Filley
C. Alan Anderson
David B. Arciniegas
A growing body of literature addresses the application of diffusion tensor imaging (DTI) to traumatic brain injury (TBI). Most TBIs are of mild severity, and their diagnosis and prognosis are often challenging. These challenges may be exacerbated in medicolegal contexts, where plaintiffs seek to present objective evidence that supports a clinical diagnosis of mild (m)TBI. Because DTI permits quantification of white matter integrity and because TBI frequently involves white matter injury, DTI represents a conceptually appealing method of demonstrating white matter pathology attributable to mTBI. However, alterations in white matter integrity are not specific to TBI, and their presence does not necessarily confirm a diagnosis of mTBI. Guided by rules of evidence shaped by Daubert v. Merrell Dow Pharmaceuticals, Inc., we reviewed and analyzed the literature describing DTI findings in mTBI and related neuropsychiatric disorders. Based on this review, we suggest that expert testimony regarding DTI findings will seldom be appropriate in legal proceedings focused on mTBI.
Demonstrating structural and functional brain abnormalities among persistently symptomatic survivors of mild traumatic brain injury (mTBI) remains a challenge in clinical medicine. Physicians, patients, plaintiffs, and attorneys are interested in identifying methods, including technology-based diagnostic tests, that offer unequivocal evidence of mTBI. In this context, neuroimaging modalities such as cerebral single-photon emission computed tomography (SPECT) have been and continue to be entered as objective evidence of mTBI in civil litigation. In a relatively recent publication,1 the Behavioral Neurology and Neuropsychiatry faculty of the University of Colorado School of Medicine performed a Daubert criteria-guided analysis of the literature pertaining to the application of cerebral SPECT to mTBI. Based on that analysis, we discuss the challenges and potential pitfalls surrounding the introduction of this specific form of neuroscientific evidence into mTBI litigation. Our ongoing experience with medicolegal applications of cerebral SPECT imaging as evidence of mTBI reveals that such practices frequently fail to comport with the Daubert analysis and recommendations offered.
Equally concerning is the continued application and commercialization of cerebral SPECT imaging for clinical purposes for which it lacks a sufficient evidence basis. The potential perils of such inappropriate deployment are well articulated in a recent exchange of letters2,3 featured in the American Journal of Psychiatry. Adinoff and Devous2 make the compelling argument that early misapplications of neuroimaging, if left unchallenged, may poison the waters such that when the technology becomes appropriate for meaningful clinical application its history of misapplication creates an untenable barrier to its acceptance in clinical and medicolegal settings: Unfortunately, if previously led astray by unsupported claims, patients and their doctors may be less inclined to utilize scientifically proven approaches once these are shown in the peer-reviewed literature to be effective. It is therefore incumbent on all of us to monitor and regulate our field. We encourage physicians to remain vigilant of unproven approaches practiced by our peers and to immediately report these trespasses to their state medical boards [Ref. 2, p 598].
Litigation, which entails an adversarial environment and is driven largely by the question of compensation can lead to transgressions that involve the misinterpretation and misuse of imaging studies. The charge issued by Adinoff and Devous2 to preserve the scientific merit of emerging technologies thus appropriately falls to the forensic psychiatrist as well.
Subsequent to our analysis of the forensic applications of SPECT in mTBI litigation, newer neuroimaging techniques have been applied in the search for more objective evidence of neuropathology in mTBI. Among the most often discussed of these currently is diffusion tensor imaging (DTI). The application of DTI to mTBI litigation is proceeding despite a paucity of critical analyses of the available data on which its use in this context is predicated. For instance, a publication by Lipton et al.4 is misrepresented in a report indicating that DTI "showed the presence of major areas of structural damage" (Ref. 5) and arguing that DTI can help "identify those patients who should receive rehabilitation earlier when it is more useful to the patient."5 The incorrect implication of such a statement is that group-level DTI findings are presently useful at the single-patient level. Statements of this kind, as well as personal in-court experience by some of the present authors, indicate that attorneys are aware of this neuroimaging technique and are prepared to use it in mTBI-related civil litigation in a manner lacking scientific precision.
At the time of this writing, a rigorous analysis of the peer-reviewed literature surrounding DTI as applied to mTBI or its application to single patients for clinical or forensic purposes has not been published. The challenges surrounding the diagnosis of mTBI, particularly in the context of litigation, and the need for such a review are articulated in an analysis of SPECT previously offered.1 In the service of providing forensic psychiatrists, a review of the points relevant to the forensic application of DTI to mTBI and related litigation, the current paper aims to provide a brief overview of DTI and its application to various neuropsychiatric conditions; a review and summary of the literature describing DTI findings in mTBI; an analysis of that literature guided by criteria established by Daubert v. Merrell Dow Pharmaceuticals, Inc., 509 U.S. 5796; and preliminary recommendations regarding the contexts and manner in which DTI might be incorporated appropriately into legal proceedings related to mTBI.
The overall goal of the following analysis is to evaluate the science of DTI as applied to mTBI and to determine what kinds of evidence are reasonably offered based on that science. As clinician-scientists, our approach is necessarily critical of the methods and interpretations of this literature and cautious about the implications of findings reported therein. We attempt to defend the science of DTI and its application to the study of mTBI against premature medicolegal application or frank misapplication and thereby preserve the scientific integrity and promise of this neuroimaging technique. DTI represents an ever-evolving research technology with powerful research potential that will hopefully lead ultimately to practical clinical applications.
Overview of Diffusion Tensor Imaging
DTI is a relatively new magnetic resonance imaging (MRI)-based data-analysis technique based on the somewhat older and clinically well established technique of diffusion-weighted imaging (DWI). Diffusion of water molecules along a magnetic field gradient reduces the magnetic resonance signal associated with those water molecules. When there is relatively little water diffusion (referred to as 'restricted' diffusion), there is little signal loss from these water molecules along the magnetic field gradient. The resulting display of this signal is intense (i.e., bright), thereby allowing DWI to serve as a marker of disrupted water diffusion in the brain, whether that disruption is due to biomechanical trauma, ischemia, hypoxia-ischemia, or some other cause. DTI is a more refined adaptation of this data analytic technique that allows for the determination of the directionality as well as the magnitude of water diffusion in the brain and more specifically within and between different brain tissue types.7 The degree of restriction of diffusion (or, conversely, the freedom of water movement) is different along (i.e., parallel to) axons from the way it is across axons.8 Water molecules will distribute themselves randomly and in all directions when movement is unimpeded, a phenomenon known as isotropic diffusion. However, in constrained environments, diffusion will predominate in directions of least resistance. Thus, in highly organized (i.e., normal) white matter tissue, the direction of water diffusion is predominantly parallel to axons; this is termed anisotropic diffusion. DTI capitalizes on these properties of water diffusion within the brain, specifically along white matter tracts, and is thereby sensitive to many processes that alter axonal or myelin integrity and hence the diffusion of water along those tracts.8,9
DTI acquires several MR images that are modified in a manner that increases sensitivity to water movement in multiple directions. The data acquired in this manner are combined and matrixed to provide information about the shape of the diffusion tensor (a mathematical term referring to the abstract object created by this matrix) at each voxel (a box-shaped element of the three dimensional space within the image of the brain), giving DTI its name.8 One commonly used measure, the fractional anisotropy (FA) value, is derived from these data. The FA value (which ranges from 0 to 1) reflects the degree to which the diffusion tensor at each voxel is isotropic (assigned a value of 0) or anisotropic (assigned a value of 1). For a more detailed but accessible overview of the fundamentals of DTI, readers may benefit from reviewing Taber et al.8
Traumatic Axonal Injury and Diffusion Tensor Imaging
White matter, which connects various cortical areas with one another as well as to the subcortical structures, brainstem and cerebellum, and the spinal cord, is vulnerable to damage when mechanical force is applied to the brain and particularly to the shearing and straining forces resulting from rotational force and angular acceleration or deceleration.10,–,12 Traumatic axonal injury, more commonly referred to in the clinical literature as diffuse axonal injury (DAI) or, perhaps more accurately, as multifocal axonal injury,13 is a common feature across the spectrum of TBI severity (see Povlishock and Christman11 for a review). Traumatic axonal injury has been described as the consequence of mechanically induced tearing of axons, with subsequent retraction and expulsion of a portion of the axoplasm that forms an axonal retraction ball. Recent evidence, reviewed in detail by Büki and Povlishock,14 suggests that while this classic model may apply to a subpopulation of axons in very severe injuries, traumatic axonal injury is more accurately understood in most cases as a progressive but relatively short-duration event (i.e., one that is measured in days) in which mechanically induced focal axonal alterations evolve through a complex cytochemical cascade to delayed axonal disconnection. White matter injury of this sort occurs diffusely, but predominates in the brainstem, cerebral parasagittal white matter, corpus callosum, and gray-white junctions of the cerebral cortex, especially at the ventral and anterior frontal and temporal lobes.13
Given the frequency of white matter damage in TBI and the ability of DTI to identify alterations of white matter integrity, there is a reasonable theoretical foundation for the application of DTI to the study of TBI and, perhaps, the clinical evaluation of persons with TBI. However, although traumatic axonal injury is a common feature of TBI, it is not an invariable one.15 Additionally, the precise contribution of traumatic axonal injury to the morbidity associated with TBI (in experimental injury models) is difficult to assess, even at the severe end of the injury spectrum.14,16 The functional relevance of traumatic axonal injury (i.e., the effect of this specific type of neuropathology not only on cognitive, psychiatric, and elementary neurologic impairments but also occupational, interpersonal, and other daily activities), as well as the relationship between DTI findings (e.g., alterations in cerebral white matter integrity) in mTBI and functional status are largely still matters of speculation. In addition, alterations of white matter integrity are present in many other neurologic and neuropsychiatric conditions and also appear to be relevant to the spectrum of normal functioning across cognitive, emotional, and behavioral dimensions.17 Accordingly, any account of the relationship between DTI findings in mTBI and functional outcome needs to account as well for the relative contributions of these other common conditions to those findings and their clinical correlates.
A review of all applications of DTI to various neuropsychiatric conditions is beyond the scope of this article. However, brief consideration of this literature will be necessary to address the specificity and limitations of DTI as a marker of traumatic axonal injury in mTBI, as well as the ability of DTI findings to differentiate between traumatic axonal injury, other neurologic and neuropsychiatric conditions, and normal healthy individuals.
DTI Findings in Neurologic and Neuropsychiatric Disorders
White et al.18 performed a review of the literature on DTI used to study psychiatric disorders, including schizophrenia, depressive disorder, anxiety disorders, obsessive-compulsive disorder, attention deficit disorder, autism, and personality disorders. Nearly 100 publications were identified. Results indicated extensive heterogeneity and substantial overlap among these conditions. Positive findings tend to predominate in the cingulum bundle (CB), corpus callosum (CC), and frontal and temporal white matter, regions in which abnormalities are also identified by DTI among groups of subjects with mTBI (review to follow). The authors noted that differences in methodologies, including scanner sequences and imaging processing algorithms, complicate the interpretation of results and that the lack of studies comparing different clinical populations precludes knowledge regarding the specificity of such findings.18 A growing body of literature reflects the breadth of conditions that might exert an impact on white matter integrity and highlights persisting uncertainty regarding the meaning and specificity of DTI findings in these and other conditions.
Paul et al.19 used DTI to compare healthy cigarette smokers with nonsmokers, and reported significantly increased FA within the CC of smokers, results generally at odds with findings of reduced FA with other substances of abuse.19,–,22 Macey et al.23 compared subjects with obstructive sleep apnea with healthy controls and reported multiple regions of reduced FA, including the CC, CB, and internal capsule (IC), among others. There are even studies indicating that early life stress24 and/or parental verbal abuse25 may result in differences in white matter integrity as measured by DTI. In short, investigation of white matter across a broad spectrum of neuropsychiatric conditions using DTI suggests that nonspecific alterations of white matter integrity are the rule and that the locations of these alterations are common to multiple conditions. This observation portends problems for the use of DTI findings for diagnostic purposes, since any such findings will entail a broad differential diagnosis of common neuropsychiatric conditions and especially for diagnostic purposes at the single-subject level.
DTI in the Mild TBI Literature: Review and Commentary
Challenges to the Interpretation and Generalization of Findings From Existing Studies
A PubMed/MEDLINE search, anchored to the terms diffusion tensor imaging, mild traumatic brain injury, and variations on this theme (e.g., mTBI and DTI), was performed. The search yielded 30 results; only those studies reporting findings specifically relating to mTBI were included for further analysis. An overview of the remaining 24 studies is offered in Table 1. As the table indicates, the methodological variation among these studies is extensive, making comparisons between them challenging, at best. With respect to the population under study, the definition of mTBI employed in these studies is highly variable: some studies define mTBI according to the American Congress of Rehabilitation Medicine (ACRM) definition48; others limit mTBI to the mildest form based on a Glasgow Coma Scale49 score of 15, whereas others permit the entire range of mTBI based on this scale (GCS, 13–15); and others employ criteria that depart from these standard definitions of mTBI. Even where standard definitions of mTBI are employed, it is not entirely clear that mTBI as defined by the ACRM is equivalent to that captured by GCS 15, and there are differences in initial injury severity and outcome between mTBI subjects whose GCS scores are 13 to 14 and those with GCS scores of 15.50,51 Between-subject and -group differences within and across these studies necessitate caution when describing findings from any of them as characteristic of persons with mTBI.
DTI and mTBI
As highlighted in Table 1, there also is substantial variability in the times after injury at which these studies were performed, ranging from the day of injury to many years later. As noted earlier, traumatic axonal injury, the neuropathologic consequence of TBI that DTI purportedly indexes, is a progressive event that evolves over the first several days to weeks after TBI.14 Since the DTI studies performed in this population are evaluating white matter changes at different stages of a dynamic neuropathologic process, the heterogeneity of findings between studies is not unexpected. That heterogeneity, driven in part by discrepancies in the time postinjury at which studies are conducted, precludes generalization of findings from any one of them to the entire population of persons with mTBI as a whole.
The approaches to the analyses of DTI data in these studies are also heterogeneous and preclude the development of a common frame of reference for the comparison of findings between studies. For example, some studies calculate apparent diffusion coefficient (ADC) as a measure of white matter integrity, while others use FA for this purpose, and still others use additional measures such as radial diffusivity (RD, reflecting myelin integrity) and axial diffusivity (AD, reflecting axonal integrity) to help determine the contribution of various types of pathology to the FA value. In addition, some studies employ hypothesis-free analyses of the whole brain and apply one of several methods of correction for multiple unplanned comparisons to identify significant findings. Other studies use a region of interest (ROI) method to test specific anatomic or anatomic-clinical hypotheses and to limit the need to perform corrections for multiple unplanned comparisons. However, even within these studies there are methodologic differences with respect to which ROI(s) are targeted, how the ROI is defined, and whether a manual (i.e., hand-traced) versus semiautomated versus automated technique is used.
A related technical problem is the lack of a large normative database, including at least age and gender as foundations for its construction, for each make and model of MRI scanner and for each software version employed on those MRI scanners used to collect DTI data. Normative databases, much as are used to guide the interpretation of serum, urine, cerebrospinal fluid, and other quantitative laboratory assessments, are needed to interpret individual (i.e., single subject or single patient) FA, ADC, or other values for clinical purposes. In the absence of population-based normative databases of these sorts, each institution at which DTI is performed is left to develop and employ their own normative data when attempting to interpret group or single-subject DTI data. The size and normality of subjects included in these databases is highly variable between institutions, rendering the interpretation of any individual DTI result as normal or abnormal based on comparison to local normative data preliminary at best.
In summary, the mTBI and DTI literature available presently is adversely affected by the differences in the definition of mTBI employed and the heterogeneity of injury captured under the term mild TBI; heterogeneity in the time after injury at which persons with mTBI have been studied with DTI; and the lack of a standard, widely used, and generally accepted method for acquiring, analyzing, and interpreting DTI data. In light of these limitations, the diverse and sometimes contradictory results produced by the studies performed to date are not surprising, and they present substantive challenges to their use in nonresearch contexts.
Examples of Specific Problems Translating Studies Into the Medicolegal Setting
Despite the limitations and challenges noted in the preceding section, DTI is a potentially powerful research tool for investigating white matter pathology across a broad spectrum of neuropsychiatric disorders, including mTBI. The work summarized in Table 1 provides foundational research with which to expand our collective knowledge of the strengths and limitations of DTI in this context. In this section, we review and critique select publications with respect to their implications on DTI for single-subject use, particularly in the context of litigation. It is important to note that this review is not intended as a critique of these studies per se but instead on the problems with translating findings from these studies from the group-level research context to that of the individual litigant.
Inglese et al.46 performed DTI histogram analysis and failed to detect any statistically significant differences between early and/or late mTBI participants and controls. However, ROI analysis did reveal significantly increased mean diffusivity (MD) and reduced FA in the CC, centra semiovale (CS), and IC of mTBI participants. This frequently cited study supports the contention that DTI may detect between group differences when comparing mTBI patients with healthy controls, and suggests that DTI is sensitive to white matter damage following such injuries. It does not, however, address the specificity of such findings to mTBI, nor does it suggest that DTI is sensitive to white matter damage at the single-subject level. As for the statistically significant between-group results, the means and standard deviations reveal the potential for substantial overlap in white matter findings between mTBI patients and healthy controls. For instance, MD at the CC splenium for late mTBI participants was .56 ± .07 and .49 ± .04 for controls; all other statistically significant results in this study demonstrate similar overlap between the mTBI and control groups. While the mean ± standard deviation differences between groups may be sufficient to permit statistical discrimination between groups at the α level of .05 or lower, any individual subject with MD values in the range of overlap between these groups cannot be reliably determined to be in one or the other group on the basis of MD value alone.
Kraus et al.7 conducted ROI DTI analysis to characterize white matter integrity across the spectrum of TBI and to examine the relationship between white matter integrity and neuropsychological performance. Although the moderate/severe TBI group demonstrated reduced FA in all ROI, the mTBI group demonstrated significantly reduced FA in the corticospinal tract (CST), the sagittal stratum (SS), and the superior longitudinal fasciculus (SLF). The mTBI group had increased axial diffusivity (AD) in the SS and SLF relative to controls, but not in the whole brain, and no significant differences were found in RD. Kraus et al.7 also examined white matter load, determining the total number or regions with FA values 1 standard deviation below the control mean. Although the mTBI group had an average load of 6 regions in which FA values were reduced, each control subject had an average of 3.6 regions of reduced FA. These observations suggest that DTI is probably very sensitive to white matter pathology following TBI, but they reveal substantial interindividual differences in white matter integrity even among healthy controls. These findings suggest that the specificity of such DTI abnormalities to mTBI, even when as well characterized as in this study, is limited. These observations illustrate well the problem of applying this technique to the examination of individual subject, patients, or litigants. In their article, Kraus et al.7 present scatterplots demonstrating the relationship between neuropsychological domain scores (executive, attention, and memory) versus white matter load for individual study participants. These scatterplots make clear the substantial overlap between the mTBI and control groups and the difficulty of distinguishing control from mTBI. Notably, results from neuropsychological testing in these groups demonstrated similar overlap. Although a trend toward greater impairment in executive function and attention for the mTBI group is reported, no significant differences were found for any neuropsychological domain score.7
Miles et al.40 conducted an investigation to determine if baseline DTI results were predictive of cognitive functioning six months after mTBI. DTI consisted of ROI analysis to determine MD and FA in the CS, the CC (genu and splenium), and the posterior limb of the IC. Patients with mTBI were found to have statistically significant higher average MD and lower average FA when compared with controls. However, baseline DTI failed to reveal any statistically significant correlations with baseline neuropsychological testing, even though 41 percent of the mTBI group was cognitively impaired on baseline testing. For follow-up neuropsychological testing, a single statistically significant correlation was found between baseline FA values and performance on prioritization form B. Notably, of the five mTBI subjects who failed to return for follow-up testing, four were not impaired at baseline testing. In addition, as the authors themselves acknowledged, psychological status and other possible confounds were not assessed.
Rutgers et al.37 performed ROI DTI analysis of the genu, body, and splenium of the CC. Patients with mTBI showed no significant difference in FA, ADC, and number of fibers for the genu, body, and splenium. However, when only those mTBI participants scanned less than three months after injury were compared with the controls, DTI abnormalities were associated with a history of mTBI. The authors suggested that DTI abnormalities in mTBI may be reversible,37 a finding that would comport with an extensive body of literature on the natural history of such injuries.52
Niogi et al.36 conducted an interesting ROI DTI analysis examining the correlation between FA in the anterior corona radiata (CR) and the uncinate fasciculus (UF) with attention and memory function in both healthy controls and mTBI patients. Although the mTBI group demonstrated a wider range of scores for attention, memory, and FA, there was considerable overlap between groups, and both featured correlations between attentional control and FA in the CR, and between memory and FA in the UF. These results suggest that tract-specific variations in white matter integrity for both healthy individuals and mTBI patients can account for variation in performance across specific cognitive domains. The fact that DTI can apparently capture anatomic differences in white matter anatomy that correlate with normal variation in cognitive performance indicates the likelihood of substantial problems regarding the specificity of abnormal findings derived from DTI, particularly at the individual patient level.
Lipton et al.35 performed a retrospective study using whole-brain, voxel-wise DTI analysis to compare participants with cognitive impairment due to mTBI with healthy controls. This group reported an overall shift toward lower FA in mTBI patients, with significantly decreased FA noted in the CC, subcortical white matter, and bilateral IC. A similar study by Lo et al.34 also compared patients with persistent cognitive impairment following mTBI with healthy controls using ROI DTI analysis. They reported decreased FA and increased ADC at the left genu of the CC in mTBI patients and increased FA in the posterior limb of the IC. Both of these studies involve retrospective designs wherein patients were identified based on persisting cognitive impairment, with the presumption that such cognitive deficits were the result of biomechanical trauma induced by mTBI. Relationships between the nature and/or severity of persisting symptoms and DTI findings were not explored. Although Lipton et al.35 and Lo et al.34 demonstrate white matter differences in their respective patient populations compared with healthy controls, given the nonspecific nature of postconcussive symptoms and the small number of subjects included in these studies, the specificity of their findings to TBI, rather than to other causes of postconcussive symptoms (e.g., depression, anxiety, and sleep disorders), remains uncertain and the translation of their findings to diagnosis of mTBI by DTI at the single-subject untenable.
Kumar et al.32 used DTI to examine the CC in the acute period following mild and moderate TBI and correlated neuroimaging findings with neuropsychological testing at six months after injury. All TBI participants experienced a loss of consciousness, and all had demonstrable computed tomographic (CT) findings at the time of injury. A significant decrease in FA in the genu of the CC was observed in the mild and moderate TBI groups; the study authors also observed an increase in RD at the genu and splenium among the mild and moderate TBI groups when compared with the healthy control group. Changes in FA, RD, AD, and MD at various locations within the CC were associated with impaired performance on various elements of neuropsychological testing. The authors concluded that CC abnormalities were more common in the moderate TBI group than in the mTBI group, with a trend toward worse cognitive outcome at six months. They also suggested that RD may prove to be a better marker of axonopathy and myelin breakdown in the early postinjury period. For the purposes of the present discussion, it is crucial to note the atypical nature of the mTBI group in this investigation, all of whom had both loss of consciousness and positive CT imaging; results based on such a study group are not likely to be generalizable to most mTBI patients or litigants. It is hardly surprising that this group of injured subjects separated from healthy controls, and such findings do little to establish the specificity of the DTI results reported. DTI data from this study were acquired during the acute injury period; it remains unclear if such findings persist into the chronic stages of injury. In addition, the authors' proposal of RD as a better marker for acute axonal injury reflects the yet-to-be-determined optimal method for DTI imaging and best metrics as applied to the injured brain.
Lipton et al.4 compared patients with mTBI and matched controls using whole-brain, voxel-wise DTI analysis and neuropsychological assessment, both within two weeks of injury, to determine whether frontal white matter diffusion abnormalities can predict acute impairments in executive function. The mTBI group performed significantly worse on neuropsychological testing, and voxel-wise analysis of FA revealed 15 clusters of significantly reduced white matter FA, 5 of which occurred in the frontal lobes. A significant relationship between three of the frontal FA measurements and neuropsychological tasks was identified, with the most robust relationship for white matter subjacent to the left dorsolateral prefrontal cortex. Although the mTBI group exhibited higher levels of depression, stress, and anxiety, correlation analyses suggested that the association between DTI findings and neuropsychological test performance was independent of such emotional factors.4 This study offers evidence that the frontal lobes and its cognitive functions are indeed vulnerable to acute biomechanical trauma as sustained in mTBI, a finding consistent with a large body of literature describing the well-established natural history of mTBI. However, these results do not facilitate prognosis at the individual subject level, including determinations of who will fail to follow the typical course of complete recovery or why they do so. These authors also discuss the relative advantages and disadvantages of voxel-wise versus ROI DTI analysis, reflecting the persisting controversies surrounding how best to apply this new technology to the injured brain.
Mayer et al.29 performed ROI DTI analysis comparing a group of mTBI subjects in the subacute period with a healthy comparison group. Clinical assessment of attention, working memory, processing speed, executive function, memory, and emotional status was also performed and compared with DTI metrics in terms of accuracy for distinguishing patients from controls. FA in the mTBI group was increased in the CC, left CR, and left UF, and RD was lower in the CC genu, left UF, and left CR. Neuropsychological testing using premorbid intelligence as a covariate did not reveal significant between-group differences. Using binary logistic regression modeling, the authors sought to determine which of their objective measures of deficits, FA or neuropsychological battery, more accurately classified subjects as mTBI versus healthy control. Both models discriminated between controls (65% accuracy) and mTBI patients (66.7%) at slightly above chance levels. The addition of traditional neuropsychological measures of attention, memory, and executive function reportedly helped little, raising accuracy to 60 percent and 71.4 percent, respectively. The addition of right and left FA indices to the model did improve accuracy, but only to 70 and 81 percent, respectively. Notably, even the best model in this recent study suggested substantial error rates when sorting healthy controls from subacute mTBI patients using the combination of DTI and neuropsychological assessment. Levin et al.28 used DTI tractography, ROI, and voxel-based DTI analysis, as well as measures of postconcussion symptoms, posttraumatic stress disorder (PTSD), global distress and depression, and cognition to compare Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) veterans with mild and moderate blast-related TBI to 15 control OEF/OIF veterans, eight uninjured subjects, and 7 with extracranial injury. Given the veteran cases and controls and the mechanism of injury investigated, results from this study may not be generalizable to civilian populations. Nevertheless, it is striking that, despite the application of several DTI analytic techniques and a patient group including several cases of moderate TBI, no group differences in either FA of ADC could be detected. Correlations between DTI findings and symptoms measures failed to achieve statistical significance, and were inconsistent. In this study, DTI failed to identify white matter injury despite persisting symptoms, including difficulties with verbal memory.28 There are several possible ways to interpret these results. Perhaps the long interval between injury and scanning allowed for natural recovery. Alternatively, the sensitivity of DTI to white matter injury following mTBI may be largely dependent on the techniques employed and parameters measured, or may simply not be as robust as previous investigations have suggested. Finally, this study may reveal problems surrounding our present gold standard for detecting mTBI, a clinical history derived from patient self-report. Exposure to biomechanical trauma frequently coincides with psychological trauma, and either may yield subjective experiences akin to feeling dazed, confused, or even unconsciousness.
In a very recent study published by the lab of one of our authors (MFK), Geary et al.27 offered perhaps the most compelling evidence to date of DTI's ability to identify lesions in postacute mTBI yielding measurable neuropsychological impairment. These authors reported a combination of statistically significant differences in FA between mTBI participants and controls, and significant relationships between FA in various ROI and neuropsychological test performance. Although the mTBI group performance on the California Verbal Learning Test-II (CVLT-II) Trial 1 was the only statistically significant between-group difference on neuropsychological testing, FA values in the UF and left SLF accounted for a significant amount of the variance.27 These data provide persuasive evidence that mTBI can produce lasting alterations in white matter integrity with neuropsychiatric implications, supporting the theory behind DTI's application to mTBI and the associated enthusiasm for this application. At the same time, these results are derived from between-group comparisons and reveal the potential for overlap between mTBI patients and healthy individuals on the applicable measures (both DTI metrics and neuropsychological test performance). Readiness for single-subject use, particularly in real-world instances involving a host of potential influences on white matter integrity, has yet to be demonstrated.
Consideration of Daubert Criteria to DTI in Mild TBI
The criteria established in the Daubert,6 General Electric v. Joiner,53 and Kumho Tire Co., v. Carmichael54 cases are intended for flexible application; such an approach will be crucial for courts considering evidence involving DTI, where the potential for variability in equipment, technique, experience level, clinical circumstances, and reporting of results is enormous. Daubert analysis is a judicial exercise to be applied on a case-by-case basis. However, in reviewing the state of the science of DTI as applied to mTBI and its appropriateness for single-subject or forensic application, Daubert criteria may usefully guide review and analysis of the medical literature. The analysis that follows is merely anchored to Daubert criteria and is not intended to supplant the need for the judicial exercise and obviously does not dictate the admissibility of DTI evidence in any given instance.
The first Daubert inquiry asks whether the theory behind and the techniques related to the performance of DTI can be, or have been, tested. On this point, DTI as applied to mTBI fares well. As previously discussed, DTI's remarkable ability to assess white matter integrity makes it a compelling choice for the study of TBI and the known white matter damage associated with such injuries. Indeed, DTI's ability to identify mTBI has already been the subject of considerable scientific inquiry at multiple institutions worldwide.
The second Daubert factor asks whether those theories and techniques have been subjected to peer review and publication. As the above literature review and Table 1 demonstrate, DTI's application to mTBI has been the subject of many peer-reviewed publications to date. However, this second Daubert criterion is arguably far more complicated than it appears and warrants deeper consideration if it is to guide determinations of evidentiary appropriateness. Although each of these studies has been subjected to peer review and publication, the lack of uniform, including some idiosyncratic, definitions of mTBI remains a major problem in the current DTI literature. This problem renders many findings from this literature difficult to compare with one another and hard to translate clinically or medicolegally. Further complicating the interpretation and translation of findings from these studies is the variability in the time after injury at which subjects were enrolled, ranging from hours to years after TBI. In terms of adherence to guidelines, no such guidelines yet exist for DTI and its application to mTBI, a problem in interpreting this body of literature for its quality.
An additional general comment regarding this second Daubert criterion warrants consideration: although DTI findings in mTBI at the group level have been subjected to peer review and publication, there are no studies that demonstrate the ability of DTI to serve as a valid and reliable diagnostic assessment of mTBI at the single-subject (patient) level. Absent any such publication, the forensic expert's need to testify with reasonable medical certainty that an individual litigant's DTI findings are attributable to mTBI is challenged. Thoughtful attention to the different missions and applications of peer-reviewed scientific publications and the court's evaluation of findings presented in those publications as legal evidence is appropriate. Peer reviewers are apt to accept manuscripts that advance the science, even if its application at the individual subject or patient level is not yet achievable; conversely, the court, in the context of mTBI litigation, is generally concerned only with application of that science to the case of the litigant. This review of the DTI and mTBI literature suggests that the research findings published thus far do not translate well from the group to the individual litigant level, and they do not appear to have been intended (by either authors or reviewers) for such translation.
The third Daubert criterion asks whether there is a known or potential error rate for the technique in question. As noted by Hoge et al.,55 attributing cognitive, emotional, behavioral, and physical symptoms to mTBI, rather than posttraumatic stress disorder, depression, or other conditions, in the late postinjury period is challenging, and may not be possible in many cases. Nonetheless, clinical interview and self-reported history remain the gold standard for clinical and research diagnosis of mTBI. In the absence of a biomarker specific for mTBI with which to confirm the history-based diagnosis, definitive determination of error rates (i.e., sensitivity, specificity, positive and negative predictive values) for DTI as a diagnostic assessment for mTBI is not possible presently. Although error rates remain unknown, the preliminary data available from the existing literature portend substantial problems in this regard: The published findings demonstrate substantial overlap in DTI findings (and their correlation with neuropsychological performance) between mTBI and control groups.7,28,29,36,46 Unaddressed in the literature is the extent to which other common neuropsychiatric conditions and environmental factors contribute to the mTBI versus control group DTI differences reported thus far. Also unaddressed is the more difficult and more typical task encountered in real-world patients: attributing DTI abnormalities to mTBI at the single-litigant level, in which mTBI frequently co-occurs with other neuropsychiatric comorbidities and environmental stressor that can affect white matter integrity. In the absence of such studies addressing the interpretation of DTI findings in this very complex real-world setting, the potential error rate of DTI as a diagnostic assessment for mTBI is simply not knowable.
The third Daubert criterion also asks whether standards exist to support quality assurance in the performance of the technology at issue. DTI, and its application to mTBI, is lacking widely accepted and commonly applied quality assurance standards. DTI research and clinical facilities differ substantially in terms of equipment and techniques, and no clear front-runner has established itself as the preferred method for such investigations. In terms of current clinical applications, variability is even more pronounced between institutions that offer DTI and the methods they employ when interpreting clinical data.
The remaining Daubert inquiry asks whether general acceptance of the theory and technique has been achieved in the relevant scientific community. Those performing Daubert analyses must pose the proper inquiry when considering this criterion. While DTI's ability to characterize white matter integrity may meet this bar, the more pertinent set of questions for evidentiary usefulness is whether DTI can identify changes in white matter integrity caused by mTBI; distinguish changes produced by mTBI from those produced by other conditions; absent distinct differences in DTI findings between conditions, parse out the relative contributions of mTBI and other conditions to a given DTI data set; and produce information that informs usefully on any neurologic or neuropsychiatric impairments and functional disability experienced by an individual subject, patient, or litigant. The most accurate answer to this set of questions, based on the present literature in this field, is no. As stated by Bigler and Bazarian, "the newness of the DTI approach indicates the need for more research" (Ref. 56, p 643).
The state of the science suggests that in most instances DTI's evidentiary appropriateness for mTBI litigation will be poor. Well-designed investigations yielding peer-reviewed publications in support of DTI's single subject use for the diagnosis of mTBI do not exist. Error rates remain unknown, but the specificity of alternations in white matter integrity is evidently problematic. Moreover, no standards exist surrounding the technical performance of DTI, or the reporting of its findings. The likelihood that an individual lab providing DTI data to a court in a given case could, at present, rise above the general state of DTI's evidentiary usefulness seems low. Also unlikely is the availability of the expertise needed to critically assess such data on a case-by-case basis to ensure that only appropriate evidence is being entered, or that the entered evidence is delivered in a manner that comports with scientific and ethical requirements.
Given the present state of the literature for DTI as applied to mTBI, the potential for this technology to be misapplied and granted far more evidentiary weight than scientifically justified seemingly exceeds the marginal value of its valid evidentiary applications. While few forensic experts have commented directly on DTI at this point, the potential for misuse of neuroimaging data in courts of law is a well-established concern.1,57,58 The example of functional neuroimaging proves illustrative in this context. The Society for Nuclear Medicine's Brain Imaging Council,59,60 in addressing the use of functional neuroimaging evidence, cautioned that the use of "nonreplicated, unpublished or anecdotal" data are "inappropriate and has ominous implications. This can lead to unsupportable conclusions if introduced as 'objective evidence'uu" (Ref. 57, p 1257). This observation seems particularly relevant to DTI and its presently unregulated state of affairs: The technological aspects and limits of DTI remain inaccessible to many experts and laypersons alike and therefore makes it likely to serve as a vehicle for medicolegal misguidance rather than clinical truth. When used this way in courts, neuroimaging may offer more in the way of jury seduction than clinical science. Because the use of DTI in TBI is predicated on a reasonably compelling and accessible theory, and because the images produced by this technology are so visually spectacular, the seductive power of DTI may be exceptional.
Careful analysis of the DTI in mTBI literature, guided by Daubert criteria, suggests that, presently, the admission of DTI evidence in mTBI litigation is seldom appropriate. Under the best of circumstances, with DTI data generated by highly experienced labs and from patients with clinically unambiguous mTBI, the imaging data may add a quantifiable measure of white matter integrity to the body of evidence describing such patients. However, in these cases DTI would serve as superfluous evidence in support of an otherwise well-established mTBI. More alarming though is the potential use of DTI to prove mTBI in cases wherein other forms of more reliable and accepted clinical evidence fail to uphold, or directly refute, such conclusions. The compelling visual images and promises of objectivity that frequently accompany such presentations of neuroimaging data may serve to seduce rather than educate triers of fact. Until DTI acquisition, analysis, and interpretation techniques are standardized, and the error rates of these techniques with respect to the diagnosis of mTBI by DTI at the single-patient level are established, published in peer-reviewed scientific journals, and generally accepted by the medical field, the authors suggest that case-by-case Daubert analysis should seldom prove favorable to the admission of DTI evidence to establish mTBI.
Admission policies in many courts are relatively liberal, however, and not all jurisdictions apply the same standards; it therefore seems likely that DTI will continue to play a role in mTBI litigation despite the current state of the science. Accordingly, medical experts, courts, and attorneys must prepare themselves for this reality and become familiar with the requirements for ethical reporting derived from other neuroimaging technologies.1,59,60 Offering an exhaustive differential diagnosis for any abnormal DTI finding regarding white matter integrity is an ethically mandated element of expert testimony when such findings are introduced as evidence. Officers of the court should be wary of any expert offering testimony involving definitive relationships between a DTI image and an illness or symptom, or refusing to identify limitations or confounding factors surrounding the study. Experts must be discouraged from claiming too much for this technology, using it to form opinions in isolation of or in conflict with other diagnostic data, or making bold cause-and-effect claims between mild TBI and white matter integrity findings.
If misused and left unchallenged, DTI imaging findings in mild TBI can be misleading. The ethical expert witness will acknowledge this fact, and the court should be prepared to exercise gate-keeping authority when the expert fails to present opinions regarding DTI data in a manner that comports with ethical requirements and scientific realities. DTI is a far too promising emerging neuroimaging technique to allow early misapplications to interfere with the eventual realization of its full potential as a research, clinical, and medicolegal tool.
Disclosures of financial or other potential conflicts of interest: None.
© 2011 American Academy of Psychiatry and the Law
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Linden High School coach of five sports retires after 50 years
Wayne Mehalick was honored Oct. 23 at the final girls soccer game, with his wife and daughter in attendance.
Linden High School coach of five sports retires after 50 years Wayne Mehalick was honored Oct. 23 at the final girls soccer game, with his wife and daughter in attendance. Check out this story on mycentraljersey.com: https://www.mycentraljersey.com/story/news/education/in-our-schools/2019/11/22/linden-nj-high-school-coach-five-sports-retires-after-50-years/4182035002/
Gary Miller, Contributor Published 5:00 a.m. ET Nov. 22, 2019
After 28 seasons of coaching Linden High School girls soccer, it would be understandable to forget some of your players' names. But Wayne Mehalick made sure that wouldn't be the case. He keeps a handwritten list of every girl who has ever played for him.
"Every year I add the names, and it's about five legal-pad pages long," he said. "They tell me, 'Why don't you put them on the computer?' I said, 'What are you crazy?'"
Linden High School girls soccer coach Wayne Mehalick was honored on Oct. 23 at the final game of the season after coaching the team for 27 years. (Photo: ~Courtesy of Linden Public Schools)
But if you start the story of Mehalick's coaching career when he took over the girls soccer program in 1992, you're coming in halfway through the movie. He has been coaching Tigers of one sport or another since 1970.
This year, Mehalick wraps up a 50-year career on the field and in the classroom, where he taught science at LHS from 1972 to 2007. Mehalick was honored Oct. 23 at the final girls soccer game, with his wife and daughter in attendance.
"My wife said, 'You finally left your first wife: Linden,"" he said with a laugh during a recent conversation. "I always loved Linden. I wouldn't trade it for the world. I had a lot of fun. It was a great ride. It went too fast.
"But I knew it was time. I'm going to be 72. It's time to take a break. Play some golf – a lot of golf!"
READ: Linden school principal moves into new position
Athletic Director Steven Viana thanks Mehalick for his unbounded dedication to Linden and especially to his players.
"We're always going to miss him," he said. "It's sad to see someone go from our Linden Athletics family who has been here for 50 years. We thank him. It's tough to say goodbye to someone who was in the district for so long. He was great. A great guy, a great coach."
Linden High School girls soccer coach Wayne Mehalick at his final game, alongside Linden Athletic Director Steven Viana. (Photo: ~Courtesy of Linden Public Schools)
Mehalick and his wife have a home close to the beach in North Myrtle Beach, South Carolina, where he plans to spend a lot more time now.
"I play golf two or three times a week," he said. "Afterward we go out for drinks and sandwiches, listen to bands. They have live beach music all over the place. It's really cool, so we enjoy ourselves."
More than anything, Mehalick's memories revolve around relationships he has made with his players. He didn't want to try to name them for fear of leaving someone out.
"There was always a line between coach and athlete. I'm not your friend," he said. "But the camaraderie was there. They still come back to see me. I have players who are 42 years old coming back. It's fantastic. I love every minute of it."
Viana said Mehalick's dedication to building relationships with his players is what set him apart from many coaches.
"You hire a coach and you expect them to know strategy and you expect them to know X's and O's and to manage a game," he said. "But what Coach Mehalick really specialized in was building relationships and a positive culture. He really taught his players things beyond the playing field. We had a little get-together for him at the end of the season, and generations of his kids came back. It was just incredible. It only happened because of the unique feeling that he gave them."
Wayne Mehalick in 1986 as an assistant coach on the Linden High School football team. (Photo: ~Courtesy of Linden Public Schools)
Mehalick is "Linden born and raised," he said, attending the old School No. 3 on Grier Avenue and Soehl Junior High School. He graduated from Linden High School in 1966, where he was a standout player on the football team as a center.
"We were the last team to use the old field house in '65, then they tore it down and built the new one," he recalled.
He went on to play at Delaware Valley College in Doylestown, Pennsylvania, and had a short semi-pro football career.
But he was destined to return to Linden. He started as a part-time football assistant coach in 1970, before being hired as a teacher in 1972. He stayed on as a football assistant until 1986.
At the start, he assumed he would stick to coaching football, until a well-respected veteran coach gave him some advice.
"Paul Blue is the one who got me involved with girls sports back in 1975," Mehalick recalled. "I told him I didn't want to coach girls sports, but I fell in love with it."
He took over the girls outdoor track team in 1975 and stayed in that position until 1997. He went on to start the girls indoor track program, coaching that from 1988 to 1997. He served as assistant coach for the softball team from 2000 to 2013, then head coach till 2016. And of course, girls soccer.
"I believe I was born to coach women," Mehalick said. "They would do anything. They would run through walls. If you told them to do something, they would do it. It was just marvelous.
"And I always treated women and guys the same, coached them the same. You treat them like athletes. You don't treat them like girls, you don't treat them like guys, you treat them like athletes, because that's what they are. And the best players are going to play."
Wayne Mehalick on his first day of retirement, Oct. 24, after coaching various sports at Linden High School more than 50 years. (Photo: ~Courtesy of Linden Public Schools)
Looking back on 50 years, Mehalick said, "It's all a blur."
"I've been through a lot of superintendents, a lot of principals, athletic directors," he said. "I've seen them come and go."
But then he quickly rattled off the names of all of his athletic directors: Seymour Kaplowitz, Al Jackuks, Frank Catale, Joe Martino, Steve Yesinko, Pauline Pagoulatos and now Viana.
Memories on the field stand out, though details may fade with the years.
He was the offensive line coach on the football team's first state championship in 1985. That was a surprise team that was picked to finish last but surprised everyone to win North Jersey Section 2 Group 3 in head coach Bucky McDonald's first season.
"When Bucky took over, that's when the football team started winning consistently year after year," Mehalick said.
Wayne Mehalick, back row middle, was an assistant coach on the Linden High School football team that won the 1985 North Jersey Section 2 Group 3 championship. (Photo: ~Courtesy of Linden Public Schools)
Whether his teams had winning seasons or not, they always played hard, he said. He recalled what an opposing coach once told him.
"When you play Linden, you better be ready, because you're going to be bleeding when the game is over," he recounted. "There were two ways you could play: You could play with skill or you could play hard. Our motto all these years was: Play hard. We didn't play dirty, but we played hard."
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Passa Sete es un municipio brasileño del estado de Rio Grande do Sul.

Se encuentra ubicado a una latitud de 29º27'12" Sur y una longitud de 52º57'41" Oeste, estando a una altura de 589 metros sobre el nivel del mar. Su población estimada para el año 2004 era de 4.582 habitantes.

Ocupa una superficie de 303,58 km².

Localidades de Río Grande del Sur


Cedar Rapids Baptist Church welcomes Christians and those who seek to connect to Christianity in the Cedar Rapids area.
Cedar Rapids Baptist Church in Cedar Rapids, Iowa is a friendly Christian community where we welcome others to join us in our worship and service to God.
This church page is missing service times. Please click here to help this page visitors by submitting Cedar Rapids Baptist Church Service Times. Thank you!
THANK YOU FOR VISITING CEDAR RAPIDS BAPTIST CHURCH ONLINE!
This church page is missing service times. Please help this page visitors by submitting Cedar Rapids Baptist Church Service Times. Thank you!


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Login to JASON Mission Center
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VSBA Partners with JASON Learning to Enhance K-12 STEM Education in Virginia
December 17, 2015 – The Virginia School Boards Association (VSBA) has identified JASON Learning as a strategic partner to provide effective and affordable science, technology, engineering and mathematics (STEM) curricula to Virginia's 1.3 million public school students.
Founded 25 years ago by the discoverer of the RMS Titanic, famed oceanographer Dr. Robert Ballard, JASON Learning is a non-profit organization that connects students to real science and exploration to inspire them to study and pursue STEM-related careers. JASON Learning links Virginia Standards of Learning aligned STEM curricula with real-life research and exploration and is shown to motivate students to excel in these challenging subjects.
"JASON Learning is showing remarkable results in engaging and educating children in subjects needed for the future," said Dr. Eleanor Smalley, president and CEO of JASON Learning, "Virginia's students bring with them a rich mixture of cultural and economic diversity, family backgrounds, and urban and rural environments. We look forward to inspiring their interest and achievement in STEM, and hopefully look to these subjects as springboards to a potential career."
Three million K-12 students across the nation take part in JASON Learning each year, which has been shown in several district-wide studies to increase interest and achievement in STEM subjects.
"The Virginia School Boards Association is proud to enter into a partnership with JASON Learning," said Gina Patterson, VSBA executive director, "Highly effective STEM instruction is vital as our public schools prepare Virginia's students to be college and career ready, and we believe JASON Learning can support these efforts."
Each comprehensive JASON Learning program includes print and digital materials, hands-on activities, videos and online games for students, as well as lesson plans, implementation tips, professional development and a powerful digital platform for educators. Live, interactive events throughout the year connect JASON participants with inspirational STEM role models, including renowned scientists and other experts in STEM fields. JASON Learning is available at the classroom, school, and division basis for a per student fee.
About JASON Learning
JASON Learning is a 501(c)(3) nonprofit organization founded in 1989 by ocean explorer Dr. Robert D. Ballard. JASON's mission is to transform K-12 STEM teaching and learning by connecting students and teachers with real science, real role models, and real exploration through world-class curriculum, teacher training, online tools, and field programs.
About the Virginia School Boards Association
The Virginia School Boards Association, a voluntary, nonpartisan organization of Virginia school boards, promotes excellence in public education through leadership, advocacy, and support. The Association offers conferences, information, training, and counseling designed to meet the needs of the Commonwealth's educational leaders. Learn more at www.vsba.org.
Copyright 2012-2015 JASON Learning
MONITORWORD


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« Rogue-ish History | Home | A Little Hate Is Good »
More Darkfallout
Matters seem to have gone from bad to worse in the Aventurine vs. Eurogamer affair, which I mentioned the other day in More Dirt Flies. In a lengthy post on the boards, Aventurine gives details and explains why they aren't in favor of a "re-review" of Darkfall.
In a nutshell, since Eurogamer won't pull the review, Aventurine believes the damage has already been done. The 2/10 rating has been picked up by Metacritic, and any new score won't make a difference, since the re-review will take time. Thus:
We don't need a re-review, we need a real review. We know for a fact that the original review is a fraud and yet Eurogamer stands by it. They should keep standing by it then or take it down based on the evidence.
Regarding that evidence, Aventurine as before is basing their stand on a combination of server logs and the flaws/mistakes in the review. They provided Eurogamer with two accounts, and going by the logs, neither Ed Zitron nor the MMO editor for Eurogamer spent much time in the game:
The reviewer's supervisor and MMO Editor for Eurogamer spent 2 minutes in the character creator but didn't create a character. Ed Zitron spent 2 hours 33 minutes logged in the game and the character creator. In this time the reviewer tried 9 different characters. Much of the time was spent creating and deleting these characters. 14 minutes before the reviewer stopped playing Darkfall altogether he said in global chat: "how do I cast spells…..help".
There is much more, and you may want to haul out the old asbestos monitor to read the piece. Aventurine is not happy, and I don't blame them for feeling that way.
Aventurine replies to Eurogamer
5 Responses to "More Darkfallout"
Wavinator	 says:
Scorpia, how much does the reputation of the developer or publisher affect the ratings of a game? Would something like this have ever happened to Microsoft or Epic? I don't know much about Adventurine's clout but I wonder how much the fear of lost revenue is a factor in what can and cannot be said in a review.
Good question, wavinator. Next question? ;)
Seriously, it's really difficult to make a pronouncement. However, I consider it unlikely that any game from a "big name" publisher would receive so low a score.
Aventurine is a small company, and has no "clout" to speak of. They don't have a lot of marketing, either. So low scores at Metacritic is bound to hurt. And, of course, the review at Eurogamer was no help at all.
On the other hand, we have the example of Stardock's Demigod. Some sites jumped in right away and gave it bad press, mainly for the tech problems.
However, Stardock's rep, and their fast response to problems has seen their MC score rise to 8.1 from users, and 7.8 from "professionals".
And this just in: since I was there to check on DG, I looked up Darkfall. They show one "professional" (ahem) review (from Eurogamer) with a 20 (of 100). On the other hand, the user vote is 7.5. So maybe Aventurine will weather this one, if more vitriol doesn't start flying.
What Scorpia failed to mention is that the score of 7.5 from players is based on 216 votes! So which score do you feel is more correct: a score of 20 from ONE review OR a score of 75 (on a 100 point scale) based on 216 votes fron players?
Now, that's a truff one. What do you think , Scropia the All-Knowing?
You can really tell when it's a full moon. As well as who hasn't heard of the Appeal to Popularity fallacy or selection bias. Or who elects to pretend that he hasn't.
Side note: Hey, google ads, good job with the ANTM youtube clip below. I'm sure it's properly licensed and has wide appeal to this site's audience.
grassBlade says:
In general, I agree that big name publishers do better in reviews, in part because of their fanboys.
NWN2's Storm of Zehir is a case in point. The Bioware forums are filled with people glossing over the obvious game bugs (I presume because they are hoping the developers will devote their time on the game editor.)
Someone like M$, however, has to be verrrry careful, since most everyone enjoys jumping on their case.


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Ban Ki-moon Condemns CAR Rebels As President Appeals For Help
UN Secretary General Ban Ki-moon
United Nations Secretary-General Ban Ki-moon has strongly condemned the armed attacks on several towns in the Central African Republic (CAR) perpetrated by the coalition of rebel groups known as 'SELEKA,' and called on all parties to refrain from acts of violence against civilians.
The rebels reportedly captured the northern city of Bambari on Sunday, having earlier seized the area around Bria, and are now said to be advancing toward the capital, Bangui.
"These developments gravely undermine the peace agreements in place and the efforts of the international community to consolidate peace in the Central African Republic," Mr. Ban's spokesperson said a statement issued on Wednesday night.
"The Secretary-General deeply regrets the loss of life and population displacement caused by the fighting," the spokesperson added.
Meanwhile, the president of Central African Republic (CAR) has urgently called on France and other foreign powers to help his government fend off rebels who are quickly seizing territory and approaching the capital.
Speaking to crowds in Bangui, a city of some 600,000, Francois Bozize on Thursday pleaded with foreign powers to do what they could. He pointed in particular to France, Central African Republic's former colonial ruler.
"France has the means to stop (the rebels) but unfortunately they have done nothing for us until now," Bozize said.
But Paris declined to offer any military assistance.
Francois Hollande, the French president, said on Thursday his country wants to protect its interests in Central African Republic and not Bozize's government.
The comments came a day after dozens of protesters, angry about a lack of help against rebel forces, threw rocks at the French Embassy in Bangui and stole a French flag.
About 200 French soldiers are already in the country, providing technical support and helping to train the local army, according to the French defence ministry.
France is encouraging peace talks between the government and the rebels, with the French foreign ministry noting in a statement that negotiations are due to "begin shortly in Libreville (Gabon)".
US officials said on Thursday the State Department was closing its embassy in the country and ordered its diplomatic team to leave.
The US ambassador and about 40 others, including a number of Americans, were flown out of Bangui to Kenya, the officials said.
Central African Republic, a landlocked nation of some 4.4 million people, has suffered decades of army revolts, coups and rebellions since gaining independence in 1960 and remains one of the poorest countries in the world.
The rebels behind the most recent instability signed a 2007 peace accord allowing them to join the regular army, but fighters' leaders say the deal wasn't fully implemented.
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1 thought on "Ban Ki-moon Condemns CAR Rebels As President Appeals For Help"
g e m o says:
what else can da UN do? These days it only condemns every mess around.


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Homepage / News / "Married" to Her Job, Erasmus Coordinator Marks 10th Anniversary at MRU
"Married" to Her Job, Erasmus Coordinator Marks 10th Anniversary at MRU
April 17th, 2015, Mykolas Romeris University (MRU) Erasmus coordinator Ieva Tondrykaitė will have front row seats at the International students' Erasmus Got Talent (EGT) Show.
"Married" to her job at MRU as she says, it wil be yet another day that she's working overtime. This time it's to watch MRU students act, sing and dance in the bi-annual Talent Show.
Although the EGT show is in the evening, she makes it a point to attend all Erasmus student events on campus, no matter what the time.
"I'm often working overtime or taking work home," said the 34-year-old who will celebrate her 10th work anniversary at MRU this June.
When she began working at MRU in 2005 there were 48 Erasmus students for the entire year. The number has now grown to 180 students this semester from about 20 countries.
"I'm the first person that students meet at MRU," she said.
Often she spends many hours in conversation, with newly-arrived students. Sometimes, she must console homesick students.
Ieva said she still receives postcards and messages from former Erasmus students who have now made their way in the world.
On a recent trip to Slovenia, MRU ex-Erasmus students showered her with gifts and gave her a tour of their country.
"I'm married to Romeris (University). My children are my Erasmus students and my Dream Team," she says speaking of the Erasmus Student Network (ESN) MRU Vilnius Team members.
"I couldn't do it without them," she says speaking of the Dream Team mentors, numbering about 50. They meet, greet and welcome International Erasmus Exchange students on campus
When not working, she's taking part in the activities of the Hot Air Balloon Club. She has been up about 20 times in Latvia, Lithuania and Poland.
Ieva also has an extensive collection of books and enjoys reading classics such as "War and Peace" and bestsellers. She is now engrossed in the novel, "Gone Girl," but has not yet seen the movie.
She collects photography albums from each country she visits with information about the country and its sights. Ieva has dozens of such books.


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Home › Reginald Bicornis by artist Julie B
Reginald Bicornis by artist Julie B
Needle Felt Rhino Necklace
(Vegan-friendly Fibers), 1.25", framed to 3.5"
The black rhinoceros or hook-lipped rhinoceros (Diceros bicornis) is a species of rhinoceros, native to eastern and southern Africa. Although the rhinoceros is referred to as black, its colors vary from brown to grey.
The species overall is classified as critically endangered, even though the South-western rhino is classified as vulnerable.
Today, there are various threats posed to the black rhinoceros including habitat changes, illegal poaching, and competing species. Civil disturbances such as war have made mentionably negative effects on the black rhinoceros populations since the 1960s.
Black rhinoceros face problems associated with the minerals they ingest as well. They have become adjusted to ingesting less iron in the wild due to their evolutionary progression, which poses a problem when placed in captivity. These rhinoceros can overload on iron, which leads to build up in the lungs, liver, spleen, and small intestine.
'Akohewili by artist Jon Ching
Hāhā'akialoa by artist Jon Ching
I'iwi Opelu by artist Jon Ching
Hāhā Kiwikiu by artist Jon Ching


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